CarlenLab

A whole-brain atlas of monosynaptic input targeting four different cell types in the medial prefrontal cortex of the mouse

Sofie — Tue, 19 Mar 2019 13:35:07 +0000

Ährlund-Richter S., Xuan Y., van Lunteren J. A., Kim H., Ortiz C., Pollak Dorocic I., Meletis K. and Carlén M.

Nature Neuroscience (2019)

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A hypothalamus-habenula circuit controls aversion

Sofie — Thu, 07 Mar 2019 11:13:43 +0000

Lazaridis, I., Tzortzi, O., Weglage, M., Märtin, A., Xuan, Y., Parent, M., Johansson, Y., Fuzik, J., Fürth, D., Fenno, L.E., et al. (2019). Molecular Psychiatry.

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Reducing pericyte-derived scarring promotes recovery after spinal cord injury

insignjohan — Thu, 22 Mar 2018 00:00:33 +0000

Dias DO, Kim H, Holl D, Solnestam BW, Lundeberg J, Carlén M, Göritz C, Frisén J.

(2018) Cell. Mar 22;173(1):153-165.e22

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An interactive framework for whole-brain maps at cellular resolution

insignjohan — Sun, 21 Jan 2018 00:00:40 +0000

Fürth D, Vaissière T, Tzortzi O, Xuan Y, Lazaridis I, Spigolon G, Fisone G, Tomer R, Deissoerth K, Carlén M, Miller C, Rumbaugh G. Meletis K.

(2018) Nature Neuroscience. Jan;21(1):139-149

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What constitutes the prefrontal cortex?

insignjohan — Fri, 27 Oct 2017 00:00:20 +0000

Carlén M.

(2017) Science. Oct 27; 285(6362):478-82. Review

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New website

insignjohan — Tue, 19 Apr 2016 06:58:52 +0000

Welcome to our new website! The page works just as well on mobile phones as on the computer. The website will be continuously updated with news about our research and so on.

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Post-doctoral position in Stockholm/Sweden

insignjohan — Tue, 19 Apr 2016 06:53:31 +0000

Postdoctoral position in neuroscience at Karolinska Institutet, Stockholm, Sweden.

The laboratory of Marie Carlén, PhD, Department of Neuroscience, Karolinska Institutet is currently accepting applications for postdoctoral positions. The Carlén lab investigates the circuit underpinnings of cognition, with a special interest in the functions of the prefrontal cortex. The research has a strong focus on inhibition, and the role of subtypes of inhibitory interneurons in cognitive processes such as attention. The lab also investigates how subcortical circuitry giving direct input to prefrontal cortex influences activities in this area, and how prefrontal cortex in turn control processing in cortical sensory areas, and ultimately shape behavior.
All projects in the lab are formulated with the aim to shed light on how brain activity and neuronal networks are affected or altered in psychiatric disorders characterized by changed cognition, such as schizophrenia.

Studies are performed using chronic recordings in conjunction with optogenetics in freely behaving transgenic mice or rats, or with acute recordings in head-fixed animals. Circuitry is targeted and traced with advanced molecular and genetic strategies.

We are looking for a highly motivated and skilled experimentalist capable of working independently as well as in close collaboration. Proven experience with single unit electrophysiology, in vivo optogenetics, rodent behavior and computer programming is prioritized, and candidates are expected to have authored high-profile publications using these techniques (at least one first author paper). Expertise in in vivo calcium-imaging or rabies tracing is also highly meriting.

To apply, please submit a letter of intent, CV and contact details of 3 academic references to marie.carlen@ki.se

Job Information

Contract length: 2 yrs with possibility of prolongation
Institution: Karolinska Institutet
Department: Neuroscience

Contact Information

Marie Carlén
Dept of Neuroscience
Karolinska Institutet
Retzius väg 8
171 77 Stockholm
Sweden
Phone +46 8 5248 3043
Email marie.carlen@ki.se

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Prefrontal parvalbumin neurons in control of attention

insignjohan — Thu, 14 Jan 2016 00:00:09 +0000

Kim H, Ährlund-Richter S, Wang X, Deisseroth K, Carlén M.

(2016) Cell. Jan 14:164(1-2):208-218

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Structural foundations of optogenetics: Determinants of chennelrhodopsin ion selectivity

insignjohan — Tue, 22 Dec 2015 00:00:08 +0000

Berndt A, Lee SY, Wietek J, Ramakrishnan C, Steinberg EE, Rashid AJ, Kim H, Park S, Santoro A, Frankland PW, Iyer SM, Pak S, Ährlund-Richter S, Delp SL, Malenka RC, Josselyn SA, Carlén M, Hegemann P, Deisseroth K.

(2015) Proc Natl Acad Sci U S A. 2015 Dec 22

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Book chapter: The Diameter of Cortical Axons and Their Relevance to Neural Computing

insignjohan — Tue, 15 Dec 2015 00:00:52 +0000

Innocenti GM, Carlén M, Dyrby TB.

(2015) Axons and Brain Architecture. Dec 15.

ISBN: 978-0-12-801393-9. Elsevier Inc.

Inlägget Book chapter: The Diameter of Cortical Axons and Their Relevance to Neural Computing dök först upp på CarlenLab.