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          Aaron Carter says he has his own experience with Michael Jackson       Comment   Translate Page      

Aaron Carter talked to TMZ. After a fake Wade Robson twitter account run by someone from Italy tweeted Aaron Carter, Aaron went on a rant to TMZ about how he wanted to punch Wade Robson. Aaron said that Wade must be lying because Wade previously defended Michael and Aaron can't see Michael doing those horrible things since his own experience with Michael was nothing but loving, caring, and innocent. Aaron also said that he slept in the same room as Michael when he was 15, nothing happened, and if it did he would have told the truth because kids blab about everything.

Aaron has now softened his position on Leaving Neverland. He said that he was too aggressive because everyone has their own stories and he wasn't a fly on the wall, so he can't know what actually happened. Aaron says that he actually has his own experience with Michael and will talk about in a book he is writing about his own life. When asked if it includes abuse, Aaron says that you will just have to find out. Aaron says that he will always have Michael's back though even if it's unflattering. Aaron says his own family knows what it is and just never talks about it, but the Jackson family/estate doesn't know. Aaron says he's not worried if it's negative because "do I ever seem worried about what I say and I keep it real as fuck." Aaron's message to the Jackson estate is that "Just stay strong. I love you guys. And even if I say something you guys don't like it's still my truth and you guys will just have to accept it."

Source: YouTube

          Famous home run ball may sell for $750,000      Comment   Translate Page      
Barry Bonds' 762nd and final home run ball will hit the auction block Monday. On Saturday, TMZ Sports reported the record-setting baseball, which is being sold through Goldin Auctions, could reach a sale price of $750,000 after previously being sold for $376,612 in 2008. Bonds' 762 homers represent
          TMZ: Barry Bonds' MLB-Record No. 762 HR Ball Could Sell for $750K at Auction      Comment   Translate Page      
Barry Bonds' 762nd and final home run ball will hit the auction block Monday. On Saturday, TMZ Sports reported the record-setting baseball, which is being sold through Goldin Auctions ...

Read the full article on Bleacher Report...


          Wendy Williams Is On The Hunt For A New Home After Filing For Divorce?      Comment   Translate Page      
It seems that Wendy Williams is moving fast with her split from her husband. Rumor has it she is looking to buy a new place asap. TMZ is reporting that the gossip queen is vetting new homes in Manhattan in an effort to distance herself from her not so better half. The tabloid website is […]
          - Aaron Carter: Doch eine andere Wahrheit?      Comment   Translate Page      
Mit dieser Wendung wird Michael Jacksons Familie sicher nicht zufrieden sein…Schließlich hatte Aaron Carter sich erst vor wenigen Wochen beim „TMZ Live“ für die verstorbene Musiklegende stark gemacht und gesagt, dass er ihn immer unterstützen würde, scheint jetzt aber offenbar eine 180 Grad-Drehung machen zu wollen.
          Victim in Fatal Nipsey Hussle Shooting Arrested for Violating Parole      Comment   Translate Page      

Many have been wondering about the status of the victims involved in the fatal shooting of Nipsey Hussle. One of the victims have been arrested for violating their parole, which is, hanging out with a gang member whom the LAPD recognize as being Nipsey, TMZ reports. A 56-year-old man by the name of Kerry Lathan […]

The post Victim in Fatal Nipsey Hussle Shooting Arrested for Violating Parole appeared first on The Source.


          Suge Knight Thinks Nipsey Hussle’s Neighborhood Loyalty Contributed To His Death      Comment   Translate Page      

Suge Knight Thinks Nipsey Hussle’s Neighborhood Loyalty Contributed To His Death Suge Knight apparently has a lot on his mind while he’s cooped up in jail and the death of Nipsey Hussle is one of them. Latest: Victim Shot In Nipsey Hussle Incident Arrested For His Gang Ties The former producer recently spoke to TMZ […]

The post Suge Knight Thinks Nipsey Hussle’s Neighborhood Loyalty Contributed To His Death appeared first on The Hollywood Unlocked.


          Бушар о материале про ее отдых на пляже: «Настоящие новости»      Comment   Translate Page      
Канадка Эжени Бушар в твиттере прокомментировала статью TMZ о том, как она отдыхала на пляже во Флориде.
          Aaron Carter and Michael Jackson: A look back at how they knew each other      Comment   Translate Page      
Aaron Carter
After Aaron Carter hinted in an interview with TMZ on Thursday that he has a bombshell of his own to drop about Michael Jackson, people have been asking questions about his past relationship with the late pop star and how the two knew each other. It is known that Aaron […]

          miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2.      Comment   Translate Page      

miR-126-3p sensitizes glioblastoma cells to temozolomide by inactivating Wnt/β-catenin signaling via targeting SOX2.

Life Sci. 2019 Apr 10;:

Authors: Luo W, Yan D, Song Z, Zhu X, Liu X, Li X, Zhao S

Abstract
AIMS: The acquired drug resistance has been regarded as a main barrier for the effective treatment of temozolomide (TMZ) in glioblastoma (GBM). MiR-126-3p is commonly down-regulated and exerts tumor-suppressive roles in kinds of human cancers, including GBM. This study was designed to investigate the functions and mechanisms of miR-126-3p in regulating TMZ resistance in GBM.
MATERIALS AND METHODS: qRT-PCR analysis was used to measure the expressions of miR-126-3p and SOX2 mRNA in GBM tissues and cells. Cell viability, colony forming ability and apoptosis were detected to evaluate the effect of miR-126-3p or SOX2 on TMZ resistance. Luciferase reporter experiments were applied to identify the target genes of miR-126-3p. Western blot analysis was performed to determine the protein levels associated with Wnt/β-catenin signaling. TOP/FOP Flash assays were conducted to determine the effects of miR-126-3p or SOX2 on Wnt/β-catenin signaling.
KEY FINDINGS: miR-126-3p expression was decreased in TMZ-resistant GBM tissues and cells. High levels of miR-126-3p enhanced TMZ sensitivity by inhibiting cell viability, reducing colony forming potential and inducing apoptosis. Additionally, SOX2 was identified as a downstream target of miR-126-3p. On the contrary, SOX2 overexpression conferred TMZ resistance of GBM cells. Moreover, miR-126-3p-mediated TMZ sensitivity was reversed following increased expression of SOX2. Furthermore, miR-126-3p-induced inactivation of Wnt/β-catenin signaling was greatly abrogated by SOX2 up-regulation.
SIGNIFICANCE: MiR-126-3p sensitizes GBM cells to TMZ possibly by repressing SOX2 expression and blocking Wnt/β-catenin signaling. This study provides novel targets to overcome TMZ resistance in GBM chemotherapy.

PMID: 30980849 [PubMed - as supplied by publisher]


          Feds Turn Up Heat on R. Kelly in Illinois Over Alleged Sex Trafficking      Comment   Translate Page      
R. Kelly's virtually getting smoked out by the feds in his own backyard as prosecutors frantically look to interview Kelly's associates in connection with their sex trafficking investigation.  Sources close to the case tell TMZ ... federal…


          Dina Lohan and Online Boyfriend Split Before Planned Meetup       Comment   Translate Page      
Dina Lohan's not gonna be meeting her online boyfriend anytime soon -- 'cause he dumped her right before they were set to finally see each other face-to-face ... TMZ has confirmed. Jesse Nadler tells TMZ ... he recently broke up with Dina after they…


          Suge Knight Says Nipsey Hussle’s Devotion To The Hood Made Him A Target      Comment   Translate Page      
Nipsey Hussle‘s tragic death has seemingly united warring gang members and has put a focus on the Los Angeles region and its gang culture as a whole. Suge Knight says that Nipsey’s devotion to the neighborhood he grew up in essentially made him a target as his fame and fortune grew. TMZ reports: Knight tells […]
                Comment   Translate Page      
ESTOS 14 ACTORES LLEVARON SU PELEA AL SIGUIENTE NIVEL
Hollywood puede parecer el lugar perfecto en donde estar; el punto de destino para todos los actores y las actrices en sus comienzos, y la tierra de fantasía de jovencitas y jovencitos, pero la tierra de cuentos de hadas en realidad tiene su propia cuota de malas lenguas, amargura, y contiendas de vida real que trascienden la gran pantalla.

Algunos de los actores simplemente no pueden soportar a sus co-actores; ya sea porque hacen bromas molestas que no son divertidas todo el tiempo, o porque son oportunistas que clavan puñales por la espalda – la lista de asuntos ocasionadores de conflicto pareciera no tener fin. Esta es quizás una vez más que podemos proclamar con añoranza “estrellas; son igual que nosotros” porque los embrollos de oficina no se limitan solo al personal de restaurantes y vendedoras. A lo largo de los años, algunas celebridades de bastante renombre han llevado su mala conducta tan lejos que otros actores se rehúsan categóricamente a aceptar cualquier proyecto que los involucre. La causa de esto es todo desde insultos dementes a conflictos de personalidad. Aquí están algunos de los embrollos de más mala fama entre co-estrellas, y echemos un vistazo a cómo fue que en primer lugar se originaron.
JIM CARREY Y TOMMY LEE JONES
El punto más alto de la carrera cinematográfica de comedia de Jim Carrey podría decirse que fue el periodo en el que protagonizó “Batman eternamente” como el personaje Riddler. Una persona que definitivamente no era un fan del estilo de comedia de Jim Carrey era ni más ni menos que su propia co-estrella, Tommy Lee Jones, quien interpretó a Harvey Dent. Miembros del elenco y del personal técnico e incluso el director, Joel Schumacher, hicieron declaraciones de que Tommy Lee Jones se presentaba todos los días al plató con mala predisposición. En una entrevista en 1996, el director le dijo a Entertainment Weekly que “Jim Carrey fue un caballero, y Tommy Lee se veía amenazado por él. Estoy cansado de defender a actores pagados de más, con privilegios de más”. El punto máximo del embrollo entre Jones y Carrey fue quizás en la noche anterior a que el par tuviera que grabar una escena juntos. Carrey declara que él y Jones se encontraron de casualidad en un restaurante y Carrey caminó hacia Jones para saludarlo. Sin embargo, el actor quedó completamente estupefacto con la respuesta que obtuvo. Carrey le contó a Howard Stern que el otro actor “…se levantó, temblando un poco, y me abrazó y dijo: ‘Te odio. De verdad no me agradas’. Y mi reacción fue: ‘Wow. ¿Qué pasa, amigo?’. Y él dijo: ‘No puedo aprobar tus payasadas’.”. Esa es una línea genial, ¿no les parece?
JULIA ROBERTS Y NICK NOLTE
1994 vio al trágico par de Julia Roberts y Nick Nolte protagonizar la comedia romántica “Uno contra todo”. Desafortunadamente, las dos estrellas no congeniaron para nada en el plató, y sus riñas por pequeñeces detrás de escena definitivamente resonaron en la pantalla como falta de química. Se puso tan feo que el director de la película, Charles Shyer, programó que tantas escenas como fuera posible se grabaron por separado para evitar que las dos estrellas estuvieran cerca el uno del otro. En medio de la filmación de la película, Julia Roberts en una entrevista con New York Times declaró que su co-estrella Nick Nolte era “completamente repugnante… parece que se esfuerza por repeler a la gente”. Nolte reiteró con su propia declaración al decir que “no es lindo llamar a alguien ‘repugnante’. Pero ella no es una buena persona. Todos saben eso.”. La pelea del par definitivamente no murió, ya que tantos años más tarde en 2009 Roberts hizo una imitación vulgar muy memorable de su antigua co-estrella durante una presentación en The Late Show. Para nada se necesitaba a un genio para entender de quién se estaba burlando.
JAMES FRANCO Y TYRESE GIBSON
Fanáticos del drama militar del 2006 “Annapolis” recordarán que se centra en el boxeo para el torneo organizado para oficiales y reclutas de la Academia Naval de los Estados Unidos. Sin embargo, las cosas tomaron un giro desagradable detrás de escena cuando la estrella James Franco llevó las cosas un poco demasiado lejos con su co-estrella Tyrese Gibson. Gibson ha publicado declaraciones en las que dice que Franco fue tan lejos que le metió piñas a su co-estrella durante ensayo para sus escenas de boxeo. Gibson le dijo a la revista Elle: “El tipo me pegaba con todo”, le dijo Gibson a Elle. “Yo siempre decía, ‘James, relájate, amigo. Solo estamos practicando’. Nunca se relajó.”Franco nunca ha admitido haber golpeado a Gibson, pero sí admitió en una entrevista con GQ que “probablemente fui un idiota”. Aunque no tan inclinado hacia las disculpas, Gibson le puso punto final cuando dijo en 2007 que “nunca quiero volver a trabajar con él, y estoy seguro de que él siente lo mismo. Se sintió muy personal. Hartó.”.
WILL SMITH Y JANET HUBERT
Seguramente los fanáticos de “El príncipe del rap en Bel Air” están al tanto de que la actriz que interpretaba a la Tía Vivian tuvo que ser reemplazada a mitad de la serie. Aunque probablemente no saben por qué. La actriz Janet Hubert era la persona original que hacía el papel de tía Vivian al principio, hasta 1993. En 1993 fue reemplazada por Daphne Reid, quien interpretó ese papel hasta que “El príncipe” terminó en 1996. Versiones e informes de parte de allegados al show y de Janet Hubert han dicho que Smith y los miembros más jóvenes del elenco no eran amables con ella en el plató. Ella dijo que los miembros del elenco “… algunas cosas crueles, horribles para mí – eran como niños malos, Will y Alfonso [Ribeiro]”. Sin embargo, Smith tiró esas acusaciones por el piso. En una entrevista de 1993 con una estación de radio, dijo que Hubert tenía una mala actitud en el plató y durante las grabaciones y que “sin importar nada más, para ella, yo simplemente soy el Anticristo”. Hubert no iba a permitir esa declaración sin defenderse, y en 2011, la actriz le dijo a TMZ que ella nunca podría volver a trabajar con Smith. “Nunca habrá un reencuentro… ya que nunca haré nada con un imbécil como Will Smith”, despotricó. “Sigue siendo un ególatra y no ha madurado.”

          Pete Buttigieg to formally launch 2020 presidential run as national buzz grows      Comment   Translate Page      

Pete Buttigieg to formally launch 2020 presidential run as national buzz growsSouth Bend mayor to make announcement at afternoon rally in his hometown against a backdrop of improving poll numbersMayor Pete Buttigieg of South Bend, Indiana, flashes a thumbs-up after speaking at a meet and greet event at MadHouse Coffee on Monday, April 8, 2019, in Las Vegas. Photograph: Bizuayehu Tesfaye/APPete Buttigieg was ready to officially launch his run for the White House on Sunday, against a backdrop of improving poll numbers and increasing national interest. The 37-year-old mayor of South Bend, the fourth-largest city in Indiana, was to make the announcement at an afternoon rally in his hometown.A big day for the openly gay Rhodes scholar Afghanistan veteran broke with a new campaign website, peteforamerica.com, a New York magazine cover – headline, “Wonder Boy” – and an interview with the tabloid website TMZ in which he revealed a love for “classic rock” like Creedence Clearwater Revival and was duly given a guitar.“Mayor Pete didn’t disappoint,” TMZ said, “as he started riffin’ Hey Joe by Hendrix!”On a more serious note, Buttigieg was asked what he would do if he made it to a presidential campaign against Donald Trump, no longer a wildly unlikely scenario, in which homophobia became a factor.“I’m kind of used to that by now,” Buttigieg said. “I’m from Indiana, I’m gay as a … I don’t know, think of something really gay, that’s how gay I am. So I’m used to bullying. I think you confront it initially and then you move on.> I’m from Indiana, I’m gay as a… I don’t know, think of something really gay, that’s how gay I am> > Pete Buttigieg“So when [Trump] does something, not just targeting the LGBT community but all the things about immigrants, putting down working people, people of colour, whoever’s being attacked at that moment, you’ve gotta confront that but you can’t let that be the end of the story.“When he lies or does something wrong you confront that and then you change the channel, change the subject back to you.”Such is the buzz Buttigieg has generated since forming an exploratory committee in January, he has rarely had to change the subject back to himself, unless it has been about his husband Chasten.In a successful effort to stand out from a crowded Democratic field, he has published a well-received memoir, toured TV studios and early voting states and performed impressively as a fundraiser, sailing past the number of donors needed to make the debates.Such success brings with it a merciless spotlight. Some observers point out that third-place polling in Iowa and New Hampshire – behind Bernie Sanders and Joe Biden but ahead of heavyweights like Kamala Harris, Elizabeth Warren and Beto O’Rourke – means little a year away from the primary.Others are beginning to focus on Buttigieg’s record in office: on Saturday CNN published a report headlined: “Pete Buttigieg pushed an aggressive plan to revitalize South Bend. Not everyone felt its benefits.”Pete Buttigieg would be the youngest president ever, at 39, if he were to win in 2020. Photograph: Ethan Miller/Getty ImagesAlso up for debate is whether the mayor’s mix of a strong personal story, hazily expressed progressive priorities and faith-based appeal to middle America may prove too good – or lightweight – to be true.In an interview published on Sunday, Buttigieg told the New York Times he was “focused on the interaction of ‘narrative and politics’ and how parties connect with people beyond policy decrees”.“The story that we tell,” the Times quoted him as saying, “not just about government but about ourselves, and the story we tell people about themselves and how they fit in, really grounds our politics.”The Times found approving voices. Dan Glickman, a secretary of agriculture under Bill Clinton who taught at Harvard when Buttigieg was there in the mid-2000s, said the mayor had developed a “way of articulating a vision which is progressive but not off-putting”.George Lakoff, a Berkeley linguist with whom the young Buttigieg corresponded, said: “He knows how to talk plainly. Usually, Democrats are saying: What are your 10 most important policy areas? And he doesn’t do that.”Buttigieg is undoubtedly having a moment. That meant that in the days before his big launch his expression of support for Ilhan Omar, the Minnesota congresswoman targeted by Trump and Republicans for her remarks about 9/11, was feverishly parsed and debated.“After 9/11,” Buttigieg wrote, “we all said we were changed. That we were stronger and more united … Now, a president uses that dark day to incite his base against a member of Congress, as if for sport. As if we learned nothing that day about the workings of hate.”He added: “The president today made America smaller. It is not enough to condemn him; we must model something better.”The campaign launch in South Bend was meant to begin that process, to present Buttigieg as a young president – he would be the youngest ever, at 39, if he were to win in 2020 – who might bridge America’s deep partisan divide.This week, the Guardian canvassed attitudes to Buttigieg in his home state, particularly among people of similar sincerely held faith, among them supporters of Mike Pence, Trump’s vice-president who is also from Indiana.Buttigieg is an Episcopalian. Pence is an evangelical with Catholic roots. The mayor has been critical of the vice-president’s support for the not notably religious Trump, for the way his Christianity shapes his politics.Curt Smith, president of the Indiana Family Institute and an opponent of same-sex marriage, said of Buttigieg: “I wish he would stop attacking the vice-president’s faith. I think that’s dangerous. But I welcome this conversation about the so-called Christian left.“It’s not a very active force in American public life and I think he could make a major contribution to the discourse in our country … I’d love to open the scriptures and do moral reasoning with people on the other side of the aisle. There hasn’t been anyone to talk to for a very long time.”



          TMZ : Justin Bieber’ın En İyi Prodüksiyonu Yolda!      Comment   Translate Page      

MuzikBuldum.
TMZ : Justin Bieber’ın En İyi Prodüksiyonu Yolda!

TMZ’ye göre, Justin Bieber ve Lil Dicky’nin yeni yayınlanacak olan şarkısının klibine birçok ünlü isim yer alacak ve bu müzik klibi Justin Bieber yaptığı en iyi prodüksiyon olacak! İşte bu müzük klibinde yer alacağı düşünülen ünlü isimler: DJ Khaled, Shawn Mendes, Halsey, Katy Perry ve Adam Levine . Müzik videosunu izleyen kişiler ise, gördükleri en […]

TMZ : Justin Bieber’ın En İyi Prodüksiyonu Yolda!
Neslihan Ünver


          Sasha Banks e Bayley protestaram contra a WWE durante a WrestleMania 35      Comment   Translate Page      
Sasha Banks e Bayley supostamente estavam tentando demonstrar insatisfação durante a WrestleMania 35 em Nova York, quando já sabiam que iriam perder os títulos.

Como informamos anteriormente, Banks se sentiu "surpresa" pela decisão de perder o Womens Tag Team Championship para as The IIconics e supostamente tentou deixar a empresa. Notamos que ela esperava ter um reinado longo com Bayley, mas isso obviamente não aconteceu.

Ryan Satin, ex-TMZ e agora jornalista do Pro Wrestling Sheet, foi ao Twitter hoje e informou que Banks e Bayley estavam no chão do vestiário no Met Life Stadium no domingo como uma forma de protesto, "fazendo com que os funcionários da WWE vissem que elas estavam insatisfeitas" com a perda dos títulos. Também foi notado que elas fizeram "cena" semelhante no hotel da WWE.
          Feds Target R. Kelly’s Camp Over Alleged Sex Trafficking      Comment   Translate Page      
R. Kelly

R&B singer R. Kelly can’t catch a break. New reports claim the crooner has federal heat on his head over alleged sex trafficking. According to reports, the feds are looking to speak to Kelly’s friends and associates. Sources close to the case tell TMZ … federal prosecutors in the U.S. Attorney’s Office for the Northern […]

The post Feds Target R. Kelly’s Camp Over Alleged Sex Trafficking appeared first on SOHH.com.


          Kofi Kingston On WWE Breaking Up The New Day      Comment   Translate Page      

Kofi Kingston reached the top of the WWE mountain at WrestleMania 35 as he defeated Daniel Bryan for the WWE Title. He recently spoke to TMZ Sports and addressed a question that fans have been asking for years about what will happen if The New Day breaks up. Kingston didn’t seem to know why people […]

The post Kofi Kingston On WWE Breaking Up The New Day appeared first on Ringside News | Wrestling News & WWE News, Rumors & Spoilers.




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