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          Stability Testing of Biological Products: 9 Challenges - Technology Networks      Comment   Translate Page      
Stability Testing of Biological Products: 9 Challenges  Technology Networks

The efficacy and safety of a biopharmaceutical product depends on the product's ability to maintain its molecular confirmation. As there is no single assay or ...


          Infographic: AI – The Secret to Sustainable Commerce      Comment   Translate Page      
Artificial intelligence has the ability to streamline business operations by analyzing vast amounts of data to target inefficiencies in the system. The infographic below, courtesy of Noodle.ai, outlines how AI can streamline the supply chain and lead to a more sustainable business and happier customers.
          Presentation Designer-Contract-Clearwater, FL ($27/hr)      Comment   Translate Page      
FL-Pinellas Park, Vaco Tampa is hiring for a client in Clearwater, FL. This is a consulting opportunity and all work must be completed on-site. Someone who can design PowerPoint, Infographics, charts, do graphic/logo design. Understanding of project scope, prioritization, and time management. Willingness to learn, take initiative, work independently, possess flexibility to adapt and troubleshoot. Ability and desire
          Infographic: 15 Mistakes That Could Tank Your Social Media Strategy      Comment   Translate Page      

There are so many ways to underserve your audience. When it comes to social media marketing, we all have a lot to lose and a lot more to gain.

The post Infographic: 15 Mistakes That Could Tank Your Social Media Strategy appeared first on Contently.


          [Infographic] Tổng hợp các nguyên nhân khiến mắt mờ và cách điều trị      Comment   Translate Page      
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          Sled pushing & pulling to enhance speed capability      Comment   Translate Page      
📲The infographics have now their own app!  Available in English, Spanish & French To find out what’s new in sport science 4 infographics / week  24.99€ / year 3-day free trial  Apple: https://itunes.apple.com/fr/app/ylmsportscience/id1409592220?mt=8 Android: https://tinyurl.com/yc3qgxsu 
          Infographic Of The Day: 20 Common Metal Alloys And What They Are Made Of       Comment   Translate Page      

Have you ever wondered where metal comes from, how humans figured out how to make brass, or why rose gold is just a slightly different hue? We've created a comprehensive chart of metals and their alloys: A list of common metal alloys like this can help us answer many questions we have about our metal tools, our everyday lives, and our universe!

Read more ...


          The Media Ignores the Yemen Missile Program. This Infographic Details Everything      Comment   Translate Page      
Randi Nord of Geopoliticsalert.com Sana’a (GPA) – For the past four years, mainstream media outlets have either twisted or completely ignored the US-backed Saudi-led war against Yemen. Yes, Yemen is the world’s worst humanitarian disaster. However, the media also tends to ignore another crucial aspect of the war: the ever-advancing Yemen missile and defense program. The […]
          All Means All      Comment   Translate Page      


Here we are, on the very cusp of Holy Week, so big thanks goes out to the Minneapolis Desk for  sending in this helpful infographic.

Everyone's welcome, except St. Paul, Jesus, and everyone else who's had the backwards, flyover country temerity to think that marriage is somehow confined to men and women.




All means ALL, peasants, so get with the program and hurry up with turning yourselves into sexless drones of the NWO hivemind. 

Think, once the patriarchal oppression of gender's removed you'll be free, at last, to do the will of your bi-coastal elite rulers. Wesley's doubtless turning in his grave.

So to cheer you up, here's this, sent in by our bureau chief in Wales:




You can sign up for a one day course on axe making here. What you do with the axe afterwards is entirely up to you.

Have a beautiful and blessed Palm Sunday.

Your Friend,

LSP

           Comment on An Overview of 2018 Tax Reform Changes [Infographic] by Nate       Comment   Translate Page      
Alissa was extremely helpful, and I am extremely happy TurboTax brought her on to help tax filers like myself this year! Thank you
           Comment on Snap A Pic of These Tax Deductions Photographers Can Take by TurboTaxKasey       Comment   Translate Page      
Hi Raymond, Some of the Meal and Entertainment changes did take effect with the 2018 tax filing. Meals with clients are now limited to 50% deduction. Also, office meals are limited to 50%. There is more information regarding the tax changes for business owners here: https://blog.turbotax.intuit.com/tax-reform/3-key-tax-reform-changes-and-facts-for-self-employed-infographic-42708/ Thanks
           Comment on An Overview of 2018 Tax Reform Changes [Infographic] by Debbie Davis       Comment   Translate Page      
Alissa was FANTASTIC!!!!! All of my issues resolved, I would recommend TurboTax to everyone!!! Could not have done this without them.... Alissa, if you see this, WAR EAGLE!!
          Comment on Top 15 SEO And Internet Marketing Forums To Learn And Promote [Infographic] by acha      Comment   Translate Page      
I love this post.i read your blog fairly often you”re always coming out with some great stuff.i shared this on my Facebook and my flowers loved it keep up the good work . Very Greek and very post. “I think this solution is helpful, and the website is easy to navigate. I think the website provides an organized database to find product reviews.”
          Video Production      Comment   Translate Page      
Video Production
2019-04-033
Implementing Rules and Regulations
Negotiated Procurement - Small Value Procurement (Sec. 53.9)

Description
Greetings from the Commission on Human Rights!

The Commission on Human Rights (CHR), through its Bids and Awards Committee for Goods and Services (BAC-GS), will procure Video Production through Section 53.9 under Negotiated Procurement-Small Value Procurement of the Revised Implementing Rules and Regulations (IRR) of Republic Act (RA) No. 9184 with an Approved Budget for the Contract (ABC) of One Hundred Thousand Pesos (PhP100,000.00) under the approved 2019 Reenacted Budget of the CHR pursuant to the 2019 CHR Annual Procurement Plan (APP).

The detailed technical specifications are as follows:

Description
VIDEO PRODUCTION:

TERMS OF REFERENCE
The Commission on Human Rights is seeking a company to create its videos for their website, social media platform, and campaigns.

Objectives:
Produce standardized videos for events and gatherings;
Provide video materials for targeted audiences; and
Create updated videos that are mass appealing and effective means to broadcast CHR priorities and messages.
User Groups/ Audiences
The intended viewers of the videos include, but are not limited to, the following
The general public
CHR clients
Academia - University professors, lecturers and other academic staff, students, student organizations
Media partners
Civil Society Organizations
Policy makers
Government agencies
Human rights advocates
International human rights coalitions/networks
CHR employees
Scope of work
Pre-production of the videos
Additional Video/Photo Shoot (if needed)
Production
Output
The services required and activities will include:
1.Pre-production:
1.1Creative and Technical Direction of the videos
1.2Storyboard
1.3Identifying platforms/channels for the resolution and aspect ratio
1.4Create assets for motion graphics and animation

2.Additional Photo/Video Shoot:
2.1 Provide additional services for video and photo shoot in case existing material from CHRs database is not enough or materials does not fit to the quality and direction of the videos.

3. Production
3.1 Create Motion Graphics and Animation for the opening/closing sequence transitions, logos and/or infographic data
3.2 Video editing

4. Outputs
4.1 Provide both soft and hard copy of the videos
4.2 Provide outputs for different platforms
- Website
- Presentation
- LED
- Social Media (Facebook and Instagram)

5. Specific responsibilities during the transition phase:
5.1 CHR must provide access to their photo and video database
5.2 An additional scriptwriter may be requested from CHR

SELECTION CRITERIA
The company should be/have:
Proven experience in video and animation production
Strong experience in creative and technical direction
Understanding of End Users needs to match with adequate technical solutions.
Proactive verification by the contractor that CHR, as a client, is satisfied with the service provided.
(Please see attached Terms of Reference)

Your quotation/proposal must be submitted together with the attached reply slip on or before 5:00PM of April 10, 2019 through email address procurement.chr@gmail.com.

Should you have concerns, you may contact the Procurement Division at telefax no. 936-6107 or mobile no. 0917-857-1607.

The CHR reserves the right to reject any and all quotations/bids, to annul the procurement process, declare a failure of bidding, to reject all quotations/bids at any time prior to contract award, or not to award the contract, without thereby incurring any liability to the affected bidder/s, and to accept only the offer that is most advantageous to the Government pursuant to Sec. 41 of the 2016 Revised IRR of RA 9184.

Truly yours,



MS. BABY CATHERINE B. CRUZ
Chief Administrative Officer
Procurement Division



          14k White Gold 1/4 Carat Genuine Diamond Solitaire Necklace      Comment   Translate Page      

$109.99

A classic diamond solitaire necklace is timeless! A round brilliant diamond is set into a 4-prong basket setting pendant.
  • Material: 14k white gold/Sterling silver chain
  • Diamond Shape: Round Brilliant
  • Diamond Carat Total Weight: 0.25
  • Diamond color: H-I
  • Diamond clarity: I1-I2
  • Chain: 18” sterling silver chain
  • Spring ring clasp

Our Fine Jewelry Guarantee

Our fine diamond jewelry selection has been carefully vetted and curated by our in-house diamond specialists. Let our years of experience encourage you to buy with confidence.

  • We guarantee that all fine jewelry products are described accurately. Please pay close attention to color and clarity gradings, as these designations accurately describe the quality of diamonds you will receive. (You can refer to our color and clarity infographic above.)
  • We offer a 30-day return policy on all fine jewelry products. This will allow ample time to have any fine jewelry product inspected by your local jeweler to ensure quality and authenticity—or your money back. We strive for nothing short of 100% customer satisfaction.
    - Note: to be eligible for return, item must be in its original purchase condition, complete with any paperwork or packaging.

We want your Tanga fine jewelry experience to be flawless and stress-free. If you have any questions or concerns, please don’t hesitate to reach out to us.


          Infographic Of The Day: American Lifespans In Decline       Comment   Translate Page      

Not all Americans are seeing their lifespans in decline, though the overall life expectancy is in decline. Obesity is the biggest single factor behind this shift.

Read more ...


          Need a designer and HTML expert      Comment   Translate Page      
Requirements. Colorful visual graphics of your research results & facts, your business data & statistics or anything else. 100% unique and professional work Pure vector file so easy to edit in future Provide you all file format like jpg, png, pdf, etc... (Budget: $250 - $750 USD, Jobs: Graphic Design, Illustrator, Infographics, Logo Design, Photoshop)
          Social Work Care Manager - PRN      Comment   Translate Page      
Posted on: 2019-04-14

You.

 

You bring your body, mind, heart and spirit to your work as a Social Work Care Manager.

 

Your compassion is tangible: patients feel it in the hand they hold. Families feel it in your prayers. Colleagues feel it in your support.  

 

Youre generous with your compassion, your partnerships and especially your voice, because your opinion matters.

 

Youre great at what you do, but you want to be part of something even greater. Because you believe that while individuals can be strong, the right team is invincible.

 

Us.

 

As a Care Manager with us, you will have the opportunity to be involved in the coordination of care and services for patients admitted to Good Samaritan Medical Center / SCL Health who are identified as needing assistance or meeting Care Management criteria.

 

Good Samaritan Medical Center is part of SCL Health, a faith-based, nonprofit healthcare organization that focuses on person-centered care. At our 234-bed Level II Trauma Center, our mission is to bring health and hope to the poor, the vulnerable, our communities and each other. Were especially proud of our people, who helped make us one of Americas 100 Best Hospitals according to Healthgrades.

 

Benefits are one of the ways we encourage health for you and your family. Our generous package includes medical, dental and vision coverage. But health is more than a well-working body: it encompasses body, mind and social well-being. To that end, weve launched a Healthy Living program to address your holistic health. Healthy Living includes financial incentives, digital tools, tobacco cessation, classes, counseling and paid time off. We also offer financial wellness tools and retirement planning.

 

We.

 

Together well align mission and careers, values and workplace. Well encourage joy and take pride in our integrity.

 

Well laugh at each others jokes (even the bad ones). Well hello and high five. Well celebrate milestones and acknowledge the value of spirituality in healing.

 

Were proud of what we know, which includes how much there is to learn.

 

Your day.

 

As a Social Work Care Manager you need to know how to:

 

        Coordinate the care and services for patients identified as needing assistance or meeting Care Management criteria. Collect in-depth information about a patients medical, functional, and social condition, to identify individual needs in order to develop a plan to meet those needs. Work with patient and family/caregivers to determine specific goals and actions based on assessment. Coordinate discharge planning. Execute specific interventions to meet established goals. Organize, integrate and coordinate the necessary resources to accomplish the goals and plan.

        Assess the patients prior level of functioning, access to and/or use of community resources and available support systems. Assist the care team in developing a plan of care which includes, but is not limited to: assuring appropriateness of services and care setting, assuring individualized support and education, determining the need for continued services, planning for discharge, and identifying and connecting patients/families with available community resources if needed. Collaborate with Physicians and other members of the health care team on the patients behalf.

        Identify appropriate admission and continued stay issues. Enhance the quality of patient care through effective and efficient use of resources. Help to identify strategies for reducing length of stay and appropriate utilization of services. Utilize criteria including clinical pathway data and implement strategies to resolve controllable variances.

        Attend, facilitate and participate in rounds and case conferences. Advocate for patient rights. Monitor efficiency and availability of services and evaluate outcomes through variance tracking, data collection.

        Identify needs, facilitate, or provide education to physicians and ancillary departments/nursing units regarding case management, discharge planning process, and roles. Participate in multidisciplinary groups and development of guidelines.

        Promote mission, vision, and values of SCL Health, and abide by service behavior standards.

        Perform other duties as assigned.

 

Your experience.

 

We hire people, not resumes. But we also expect excellence, which is why we require:

 

        Graduate of an accredited school of Social Work, Sociology, or related field, required

        Minimum of one (1) year of clinical experience, required

        At least two (2) years of case management experience in an acute care setting, preferred

        Masters Degree in Social Work (MSW), preferred

        Current Colorado Social Worker license or ability to obtain, preferred

 

Your next move.

 

Now that you know more about being a Social Work Care Manager on our team we hope youll join us. At SCL Health youll reaffirm every day how much you love this work, and why you were called to it in the first place.




          Certified Sterile Processing Tech - SPD      Comment   Translate Page      
Posted on: 2019-04-14

You.

 

You bring your body, mind, heart and spirit to your work as an Instrument Tech in Sterile Processing.

 

Youre great at what you do, but you want to be part of something even greater. Because you believe that while individuals can be strong, the right team is invincible.

 

Us.

 

Good Samaritan Medical Center is part of SCL Health, a faith-based, nonprofit healthcare organization that focuses on person-centered care. At our 234-bed community hospital, our mission is to bring health and hope to the poor, the vulnerable, our communities and each other. Were especially proud of our people, who helped make us one of Americas 100 Best Hospitals according to Healthgrades.

 

Benefits are one of the ways we encourage health for you and your family. Our generous package includes medical, dental and vision coverage. But health is more than a well-working body: it encompasses body, mind and social well-being. To that end, weve launched a Healthy Living program to address your holistic health. Healthy Living includes financial incentives, digital tools, tobacco cessation, classes, counseling and paid time off. We also offer financial wellness tools and retirement planning.

 

We.

 

Together well align mission and careers, values and workplace. Well encourage joy and take pride in our integrity.

 

Well laugh at each others jokes (even the bad ones). Well hello and high five. Well celebrate milestones and acknowledge the value of spirituality in healing.

 

Were proud of what we know, which includes how much there is to learn.

 

Your day.

 

As an Instrument Tech you need to know how to:

 

          Assist the surgical team as one of the primary scrub personnel to provide the proper instruments and supplies during surgical procedures.

          Provide coverage on the night shift as a scrub tech to the main OR

          Properly open the tables for the sterile field in OR

          Properly stock and categorize sterile processing instruments and equipment

          Inventory supplies after surgical procedures are completed

 

Your experience.

 

We hire people, not resumes. But we also expect excellence, which is why we require:

 

          High School diploma or GED is required

          Graduate of a Surgical Technology program is required as this position will cover night shift scrub procedures in the OR

          Certification in Sterile Processing is required

          Basic Life Support (BLS) certification upon hire is required

 

Your next move.

 

Now that you know more about being an Instrument Tech on our team we hope youll join us. At SCL Health youll reaffirm every day how much you love this work, and why you were called to it in the first place.



          Clinical Nurse Educator - RN - Emergency Department - ED      Comment   Translate Page      
Posted on: 2019-04-14

You.

 

You bring your body, mind, heart and spirit to your work as an Emergency Department Registered Nurse Educator.

 

Your compassion is tangible: patients feel it in the hand they hold. Families feel it in your prayers. Colleagues feel it in your support.

 

You know when to move quickly. When to sit quietly. When to laugh loudly.

 

Youre great at what you do, but you want to be part of something even greater. Because you believe that while individuals can be strong, the right team is invincible.

 

Us.

 

Our busy 40-bed Emergency Department sees very high-acuity patients of all demographics and treating more than 42,000 patients/year. Our Emergency Department provides full-service and specialized care, including:

 

        Certified Chest Pain Center

        Primary Stroke Center

        Level II Trauma Center

        Cardiovascular Center of Excellence

        Emergency services for mental and emotional health

        Fast-Track ED for evaluating and treating less serious conditions quickly

        Telemedicine

        Community education trauma and injury prevention as well as CPR/first aid education at local schools and events

 

Good Samaritan Medical Center is part of SCL Health, a faith-based, nonprofit healthcare organization that focuses on person-centered care. At our 234-bed Level II Trauma Center, our mission is to bring health and hope to the poor, the vulnerable, our communities and each other. Were especially proud of our people, who helped make us one of Americas 100 Best Hospitals according to Healthgrades.

 

Benefits are one of the ways we encourage health for you and your family. Our generous package includes medical, dental and vision coverage. But health is more than a well-working body: it encompasses body, mind and social well-being. To that end, weve launched a Healthy Living program to address your holistic health. Healthy Living includes financial incentives, digital tools, tobacco cessation, classes, counseling and paid time off. We also offer financial wellness tools and retirement planning.

 

We.

 

Together well align mission and careers, values and workplace. Well honor each others dignity and surpass the standards we set. Well encourage joy, demand safety and take pride in our integrity.

 

Well laugh at each others jokes (even the bad ones). Well hello and high five. Well celebrate milestones and acknowledge the value of spirituality in healing.

 

Were proud of what we know, which includes how much there is to learn.

 

Your day.

 

As an ED RN Educator you need to know how to:

 

        Provide clinical expertise for patients, families as well as for a variety of health professionals

        Utilize the nursing process for each patient through the nursing assessment, planning, implementation and evaluation

        Assist in coordinating a multi-disciplinary approach to patient care with other members of the care team

        Provide individual and group education to patients and families

        Provide accurate assessments of a patients physical and emotional status, identify learning needs and any unique special requirements needed to facilitate a positive learning environment for the patient and patient support/family

        Provide education, both formal and informal, for patients, families, members of the health care team and the community within the Emergency Department

        Act as a resource person to health care professionals in the Emergency Department

        Consult with physicians regarding patients treatment and educational plans

        Develop communication tools to support effective education and disease management

        Promote mission, vision, and values of SCL Health, and abides by service behavior standards

        Performs other duties as assigned

 

Your experience.

 

We hire people, not resumes. But we also expect excellence, which is why we require:

 

        Bachelors Degree in Nursing, required

        Master's Degree in Nursing, preferred

        Current Colorado RN license, required

        Current BLS, ACLS and TNCC certifications, required

        Current PALS or ENPC certification, required

        Minimum of three (3) years of relevant nursing experience and two (2) years of previous formal education activities, required

 

Your next move.

 

Now that you know more about being an ED RN Educator on our team we hope youll join us. At SCL Health youll reaffirm every day how much you love this work, and why you were called to it in the first place.



          Director of Quality      Comment   Translate Page      
Posted on: 2019-04-14

You.

 

You bring your body, mind, heart and spirit to your work as a Director of Quality.

 

You know how to move fast. You know how to stay organized. You know how to have fun.

 

Youre equally comfortable with leading Quality programs, interpreting and presenting Data, aligning with Performance Excellence initiatives, managing Infection Prevention, Personnel management and oversight, and Fiscal responsibilities.

 

Youre great at what you do, but you want to be part of something even greater. Because you believe that while individuals can be strong, the right team is invincible.

 

Us.

 

Reporting directly to Good Samaritans CNO and CMO, the Director of Quality will also interact with system leaders as the primary owner of quality, infection prevention and performance excellence for the care site.  With approximately 4 direct reports, and additional indirect reports, this leader is accountable for educating stakeholders on all aspects of quality.

 

Good Samaritan Medical Center is part of SCL Health, a faith-based, nonprofit healthcare organization that focuses on person-centered care. At our 234-bed Level II Trauma Center, our mission is to bring health and hope to the poor, the vulnerable, our communities and each other. Were especially proud of our people, who helped make us one of Americas 100 Best Hospitals according to Healthgrades.

 

Benefits are one of the ways we encourage health for you and your family. Our generous package includes medical, dental and vision coverage. But health is more than a well-working body: it encompasses body, mind and social well-being. To that end, weve launched a Healthy Living program to address your holistic health. Healthy Living includes financial incentives, digital tools, tobacco cessation, classes, counseling and paid time off. We also offer financial wellness tools and retirement planning.

 

We.

 

Together well align mission and careers, values and workplace. Well encourage joy and take pride in our integrity.

 

Well laugh at each others jokes (even the bad ones). Well hello and high five. Well celebrate milestones and acknowledge the value of spirituality in healing.

 

Were proud of what we know, which includes how much there is to learn.

 

Your day.

 

As a Director of Quality you need to know how to:

 

        Assure all departments, both clinical and non-clinical, have quality metrics identified, and meet acceptable parameters.

        Review NDNQI indicators and work with Nursing Leadership to assure actions are in place to meet top decile performance nationally.

        Work with contract owners to assure contract quality metrics are identified, reported, with actions taken as needed to remain within parameters acceptable within the industry and organization.

        Lead stakeholders to an understanding of quality in their areas of responsibility.

        Work with CMO to assure Providers receive data in understandable, cogent format.

        Remain current on all quality-related regulatory requirements, to include those required by The Joint Commission, CMS, local, State, and Federal entities.

        Facilitate all logistics of Performance Excellence Committee, and other quality-related meetings.

        Assure updates and Board approval is obtained on mandated annual Quality Plan.

        Assure all quality related items on System Operational Performance Goals are met to the maximum level of achievement.

        Prepare materials for Quality Committee of Board, and other requests. 

        Present data internally to key stakeholders, with corresponding explanations and action plans.

 

Your experience.

 

We hire people, not resumes. But we also expect excellence, which is why we require:

 

        Bachelors Degree in Nursing or equivalent, in healthcare/business administration or related area, required

        Minimum of six (6) years of experience with progressively increasing levels of responsibility in total quality improvement function, required

        Minimum of five (5) years of experience in a leadership role, required

 

Your next move.

 

Now that you know more about being a Director of Quality on our team we hope youll join us. At SCL Health youll reaffirm every day how much you love this work, and why you were called to it in the first place.



          Compnay profile in PPT format      Comment   Translate Page      
I'm looking for a PPT design, we are looking for a clean, visual, less words more pictures and icons (examples attached) (Budget: $30 - $250 USD, Jobs: Graphic Design, Illustrator, Infographics, Photoshop, Powerpoint)
          Compnay profile in PPT format      Comment   Translate Page      
I'm looking for a PPT design, we are looking for a clean, visual, less words more pictures and icons (examples attached) (Budget: $30 - $250 USD, Jobs: Graphic Design, Illustrator, Infographics, Photoshop, Powerpoint)
           Comentario en Cómo evitar estafas si eres freelance #infografia #infographic #emprendedores por Cómo evitar estafas si eres freelance #infografia #infographic #emprendedores       Comment   Translate Page      
[…] Author: alfredovela Go to Source […]
           Comentario en Cómo evitar estafas si eres freelance #infografia #infographic #emprendedores por Cómo evitar estafas si eres freelance #infografia #infographic #emprendedores – Metabuscador de empleo       Comment   Translate Page      
[…] post Cómo evitar estafas si eres freelance #infografia #infographic #emprendedores appeared first on TICs y […]
           Comentario en Redes sociales con más usuarios activos #infografia #infographic #socialmedia por Redes sociales con más usuarios activos #infografia #infographic #socialmedia – Metabuscador de empleo       Comment   Translate Page      
[…] post Redes sociales con más usuarios activos #infografia #infographic #socialmedia appeared first on TICs y […]
          Slaying the Largest Homebuying Myths Today [INFOGRAPHIC]      Comment   Translate Page      
Some Highlights: The average down payment for first-time homebuyers is only 6%! Mortgage interest rates have been on the decline since November! Hop in now to lock in a low rate! 88% of property managers raised their rents in the last 12 months! The average credit score on approved loans continues to fall across many […]
          Infographic Of The Day: American Lifespans In Decline       Comment   Translate Page      

Not all Americans are seeing their lifespans in decline, though the overall life expectancy is in decline. Obesity is the biggest single factor behind this shift.

Read more ...


          The Ketogenic Diet and Its Physiological Effects on the Human Body      Comment   Translate Page      

In this interview, Benjamin Bikman, Ph.D., an obesity and diabetes scientist and associate professor of physiology and developmental biology at Brigham Young University (BYU) in Utah,1 reveals how the ketogenic diet affects your physiology and supports optimal health.

“My main interest early on was looking at how the body adapts to obesity,” he says. “That was my master’s thesis. My master’s degree was exercise science here at BYU … I ended up pursuing a Ph.D. in bioenergetics at East Carolina University, under this wonderful scientist named Lynis Dohm, Ph.D.

His focus had been looking at how lipids cause insulin resistance. That was an interest of mine, because I thought this was starting to explain why and how the body becomes insulin-resistant in the midst of obesity … Insulin resistance is that connection.

During my Ph.D., we were looking at inflammation in people who were losing weight following gastric bypass procedures and how improved inflammation is likely part of the improvements in insulin sensitivity that people see post-bypass.

I followed that up with a post-doctoral fellowship at … the Duke National University of Singapore. They had this focus on cardio metabolic disorders. I … looked at inflammation as a particular mediator there … Then in 2011, my alma mater, BYU, came knocking. They wanted to do more diabetes research, and I fit the requirements … That got me, essentially, to where I am now …

If I really am getting this conviction, based on my own research, that insulin is key to not only diabetes but to almost every chronic disease, what is the best way to control insulin? That was when I insisted on only looking at published human clinical data — not rodents, not cells, not epidemiology, just clinical data.

The low-carb diet was just this very effective way to do that. That then got me interested in asking questions about ketones, which is what my lab is doing … how ketones are regulated by insulin.”

Bikman’s conviction that insulin is a key to health and disease prevention, and that controlling carbohydrate intake is the most effective way to control insulin, led him to start practicing what he’d learned. He went on a low-carb diet about eight years ago. “Sure enough, at middle age, it’s helped me stay healthy,” he says.

Most Americans Are Insulin Resistant

Unfortunately, many, including doctors, still do not understand the influence of insulin on health and disease. The late Dr. Joseph Kraft, former chairman of the department of clinical pathology and nuclear medicine at St. Joseph’s Hospital in Chicago, wrote the book “Diabetes Epidemic and You: Should Everyone Be Tested?”

In it, he presents data that suggests 80 percent of Americans are in fact insulin resistant, or have “diabetes in situ.” Based on data from 14,000 patients,2 Kraft developed a powerful predictive test for diabetes.3 He would have the patient drink 75 grams of glucose, and then measure their insulin response over time, at half-hour intervals for up to five hours.

He noticed five distinctive patterns suggesting that a vast majority of people were already diabetic, even though their fasting glucose was normal. Only 20 percent of patients had healthy post-prandial insulin sensitivity and low diabetes risk. According to Kraft, “Those with cardiovascular disease not identified with diabetes … are simply undiagnosed.”

One of the take-home messages here is that insulin resistance and hyperinsulinemia (a condition marked by excess insulin in your blood relative to your level of glucose) are two sides of the same coin, as they drive and promote each other. In other words, if you have hyperinsulinemia, you are essentially insulin resistant and on your way toward developing Type 2 diabetes.

High Insulin Is a Key Disease Promoter

Both insulin resistance and hyperinsulinemia promote fatty liver and high blood glucose, and both of those in turn promote atherosclerosis. High blood pressure is another side effect of insulin resistance that drives atherosclerosis by placing stress on your arteries.

The effects of insulin resistance are really at the heart of most if not all chronic degenerative diseases. Diabetes, heart disease, cancer and Alzheimer’s are just a few of the most obvious ones. The logical conclusion then would be that addressing insulin resistance is a foundational component of effective health care. Bikman says:

“When I teach this to my students … I put insulin resistance in the core. Around it, I have all these chronic diseases. It’s what I call the ‘wheel of misfortune.’ Really, the most common cancers, prostate and breast cancers, almost always … will heavily express — by six or seven times — the number of insulin receptors. So, insulin is promoting the growth of the tumor.

With dementia, the connection between insulin resistance and Alzheimer’s is so tight that people refer to it as Type 3 diabetes. With sarcopenia, we know that if a muscle becomes insulin-resistant, that actually diminishes insulin’s ability to promote the anabolic production of proteins within the muscle …

We have to have our medical practitioners start appreciating … the utility [of] measuring insulin, because our focus on measuring glucose misses the mark. As someone’s becoming insulin-resistant, their insulin is climbing, but it’s enough to keep their glucose in check.

And because we always look at glucose, we don’t catch the disease until they become so insulin-resistant that no amount of their own insulin is enough to keep the glucose in check. Now, the glucose starts to climb — 10 years later, perhaps — and that’s when we detect the problem. We’re looking at the wrong marker.”

How the Ketogenic Diet Improves Insulin Sensitivity

The question then becomes, how do we treat insulin resistance? As Bikman’s research reveals, the ketogenic diet is part and parcel of the “cure” for this condition.

“For me, the benefit of a low-carb ketogenic diet is that it addresses the endocrine aspect of metabolic health,” Bikman says. “For too long … the message has been completely focused on calorie number.

It is this idea that if you can simply put a person into caloric deficiency, they will lose weight — problem solved … But we know that has long-term consequences … There’s a lasting metabolic damage …

Nevertheless, the power of the low-carbohydrate diet is that it addresses the endocrine component. As important as calorie number is, and I can appreciate the laws of thermodynamics … we cannot ignore the relevance of hormones, especially insulin.”

As explained by Bikman, it’s important to realize that insulin is what dictates what your body does with the energy it has — the energy you consume and the energy you have stored. “Insulin has its strong, capable hands right on the steering wheel of what the body does with the energy that it has available,” he says.

Importantly, research shows your metabolic rate increases as insulin decreases. “To me, that’s the power of the low-carb diet. You’re controlling insulin, and that can start to address all of those chronic diseases,” Bikman says.

The Importance of Cycling High and Low Carbohydrate Intake

For all its benefits though, there are drawbacks to staying in chronic nutritional ketosis. Based on the evidence, I’m convinced one needs to pulse or cycle in and out of nutritional ketosis. Bikman, who is in general agreement with this idea, explains:

“As a scientist, I wish there were longer-term studies to be able to conclusively say you can’t do this long-term or you can. What I’m comfortable saying, with a little bit of speculation, is that … the avoidance of carbohydrates for a prolonged period will create this situation of a relative glucose intolerance.

Now, I’m not going to say that causes insulin resistance. Some people say low-carb [diet] causes physiological insulin resistance … To me, a low-carb diet can create a situation of carbohydrate intolerance. That is reflective of a general and very substantial shift in energy use.

Insulin is down — that means the body is in fat-burning mode. That is the absolute bioenergetic fuel. If insulin is low, you are fueled with fat. That can create a shift where the body becomes almost reluctant to fuel itself with carbohydrates.

That’s where you have instances of someone adopting a low-carbohydrate diet, and then they’ll eat a carbohydrate load and they’ll say, ‘Wow, my glucose levels; it’s like I’ve become diabetic.’ That’s not the same thing. They become glucose-intolerant.

If that’s something someone wants to avoid for whatever reason, then cyclical [keto] is probably the way to go. You kind of spike the glucose from time to time, maybe weekly, whatever would work best for the person … The idea [is] you have that frequent-enough exposure to carbohydrates so that you can maintain that tolerance to the carbohydrates …”

Insulin also suppresses the liver’s ability to produce glucose. It impairs gluconeogenesis. What this means is that if your insulin level is too low for too long, your glucose level can start to rise. While this is not universally true for everyone, it can occur, as it did for me. Cycling in and out of ketosis will help you avoid this paradoxical side effect as well. Bikman notes:

“I’ve heard enough people say that. I think it has to be taken seriously. Nevertheless, glucagon [hormone] starts to climb. Insulin’s main effect is to take glucose from the blood (or any fuel) and push it into the cells. Glucagon does the opposite. Glucagon wants to mobilize fuel from tissues and push it into the blood.

One of glucagon’s main actions is to promote the breakdown of stored glycogen to promote the production of glucose in the liver. In that instance, where insulin has gone too low then, theoretically, glucagon could go too high, and that could increase glucose too much … That’s kind of reflective, perhaps, of that intolerance I mentioned …

With regards to the context of low-carb [causing] glucose to climb over time, it could be due to the lack of insulin, and thus an absence of the inhibition of glucagon production from the pancreas. The pancreas is making too much glucagon. That could potentially be driving up glucose levels.”

The Connection Between Gut Bacteria and Liver Health

Bikman also summarizes how a high-fiber diet helps combat fatty liver disease, which it does by way of influencing your gut microbiome.

“While the human body doesn’t get any energetic benefit from the fiber, the bacteria do. The bacteria are able to use the fiber as fuel. One of the products of that is short-chain fatty acids, [such as] butyrate.

What’s interesting is that as the fiber is being digested by the bacteria to create butyrate, that short-chain fat can get absorbed into the body … [I]t goes right into the portal vein from the gut, right to the liver …

Short-chain fatty acids are so stimulatory with regards to mitochondrial biogenesis … that it actually can combat fatty liver disease. It’s kind of a fun little paradox of using a fat to fight the fat that’s stored in the liver, in the case of fatty liver disease. Nevertheless, that’s an odd little connection between gut bacteria and liver health.”

Butyric acid (butyrate, a short-chain fatty acid produced by bacteria in your gut) is really similar to the ketone hydroxybutyrate, produced by your liver during the conversion of fat into energy.

The primary difference between the two is that hydroxybutyrate isn’t as absorbable. Most of it is used locally by colonocytes (epithelial cells of your colon). In other words, hydroxybutyrate is used for fuel in your gut, while butyrate benefits your liver.

The Mechanistic Target of Rapamycin — A Driver of Ill Health

The mammalian target of rapamycin (mTOR), also known as the mechanistic target of rapamycin, is an incredibly important pathway, as it controls autophagy — your body’s natural clean-up process in which old, damaged cells are eliminated and replaced with new, healthy ones. As such, it also plays an important role in aging and cancer.

In short, to slow aging and reduce your risk of cancer, you want to inhibit mTOR, as this triggers autophagy. When mTOR is activated, autophagy is deactivated, which prevents the recycling of proteins. Alas, chronic suppression of mTOR is not ideal either. Bikman explains:

“What’s important with regards to mTOR … is that because it inhibits autophagy, it is thought to allow proteins and just organelles, parts of the cells, to get old due to things like oxidative damage. As those proteins get damaged, they get old, and then the cell, by extension, gets old.

As the cells get old, so too is the organ, and then the whole body … But … the body has been designed with far too clever a scheme to have something that shouldn’t be there; mTOR is so fundamental to life that you can’t just go in and just slam the breaks on it, because that is death. We have to grow. We have to allow a cell to grow, and tissue to grow.

This idea [is to] optimize or strategically focus on boosting mTOR and letting it come back down to keep the body young, to keep the cells cleaning themselves out through autophagy … Then you inhibit that and allow the body to grow with this cyclical spike of mTOR.

A lot of the focus … among vegetarians … is this idea that you’ve got to avoid animal protein because it spikes mTOR. That’s the wrong way of looking at it … What spikes mTOR the most and the longest? Insulin spikes mTOR far more than amino acids do.”

Insulin Activates mTOR to a Far Greater Degree Than Protein

In other words, sugar/carbohydrates are the No. 1 enemy when it comes to activating mTOR and driving the aging and disease processes. According to Bikman, a direct comparison in tissue shows insulin spikes mTOR three to four times higher than leucine, the amino acid that has the greatest impact on mTOR, raising it the most.

Importantly, while amino acids such as leucine, or protein in general, will spike mTOR for 45 to 90 minutes, after which mTOR dials back down, if you eat lots of starchy, sugary foods, you have chronically elevated insulin and hence chronically activated mTOR, and that’s what’s causing problems.

“If you look at the global breakfast trends, it’s going to be something starchy and sugary. Insulin will come up, depending on the person, [and stay elevated for] two to even four hours; mTOR is active that whole time. Then, right as the insulin is coming down, they have a mid-morning snack.

Of course, it’s another starch and it’s another sugar. Insulin comes up again and it’s up for hours. Of course, as insulin is up, so too is mTOR. That, I submit, is far more pathological — this chronic, every-waking-moment mTOR activation because of insulin, rather than these intermittent spikes of mTOR because of the ingestion of protein.”

The Benefits of Intermittent Fasting

Aside from a ketogenic diet, intermittent fasting — where you do not eat for 16 to 18 hours a day; 12 hours being the absolute minimum — is another effective way to regain your insulin sensitivity and control mTOR.

Basically, while you’re fasting, your insulin will dramatically drop, allowing your body to enter into autophagy and clean itself out. Then, when you refeed, your body deactivates autophagy and starts to rebuild itself.

Dr. Jason Fung, a nephrologist, recently published a case series paper4 on three diabetic patients — all of whom were on high doses of insulin — detailing how intermittent fasting can be used as a therapeutic alternative for Type 2 diabetes.

Of the three patients, two did alternating-day 24-hour fasts, while one fasted for 24 hours three times a week over a period of several months. On nonfasting days, they were allowed both lunch and dinner, but all meals were low in sugar and refined carbohydrates throughout. (The complete manual of the fasting regimen used is described in Fung’s book, “The Complete Guide to Fasting.”5)

Two of the patients were able to discontinue all of their diabetes medications while the third was able to discontinue three of his four drugs. All three also lost between 10 and 18 percent of their body weight. Incredibly, all were able to discontinue their insulin in just five to 18 days. Bikman comments:

“From the context of controlling insulin, there are studies on insulin-resistant people where they are on isocaloric diets, so the same amount of calories, but one is eating them frequently in smaller amounts and one is packing them in a smaller window …

Those on the time-restricted eating schedule … had greater drops in glucose and insulin. That, to me, is the beginning and end. As a guy who sees the relevance of insulin in any chronic disease … I just simply ask, what controls insulin?

Simply give your body a break from eating. Twelve hours should be what everyone does every night of the week, even if they’re eating three full meals. At least get that 12-hour break, for heaven’s sake.

As a professor, I see kids who live on cold cereal. They’re eating three bowls of cereal at midnight. [Then] they have the same three bowls of cereal at 7 or 8 a.m. I hear them, of course. They’re smug, ‘I can eat whatever I want.’ I say, ‘Let’s see how you’re doing in 10 years.’”

The reason you want to avoid eating for 16 to 18 hours is because you cannot effectively deplete the glycogen stores in your liver otherwise. As noted by Bikman, your liver will hold, on average, 100 grams of glycogen, and it takes anywhere between 24 and 48 hours to burn that up.

What this means is that if you’re eating a high-carb diet and want to get into ketosis, you’ll need to totally restrict carbohydrates or fast for at least 24 hours. Once you start running out of glycogen, your ketones will start to rise to take its place as a fuel for your body. Around 48 hours, you’re solidly in ketosis as the glycogen in your liver has been cleared.

On a side note, fasting will also release fat-bound toxins and facilitate detoxification. As noted by Bikman, “as insulin comes down, your urine production starts to increase,” as your kidneys start to flush out toxins.

Industrial Seed Oils — Another Culprit That Drives Disease

The devil’s in the details, of course, and the main problems are caused not only by refined carbohydrates in the Western processed food diet but also by processed seed oils, which Bikman describe as “surprisingly pathogenic.”

“We’ve just started a project in my lab. I’ve got a really sharp undergraduate who’s focusing on the main oxidized product of seed oils,” he says. “When you look at that main omega-6 and how it gets oxidized through this molecule called 4-hydroxynonenal (4-HNE), we’re looking at how it accumulates in muscle cells.

It is forcing these changes in the way the mitochondria are physically put together. Mitochondria love to be very dynamic. They’re long and stringy. They’ll separate often to small pieces then come back together. Not all have a very relevant physiological purpose with regards to cell growth and division.

Yet, in the case of 4-HNE accumulation, that process gets stopped. Now you’ve forced this sustained static state of the mitochondria, which is not healthy for them or the cell. I can’t say anything more about it yet just because we don’t have all the data yet, but it’s coming.”

Ketones — A Surrogate Marker for Insulin

While measuring insulin is really valuable, you need a doctor’s order to test it. Fortunately, there’s a good surrogate marker for insulin, namely your ketone level, because you cannot have high insulin if you have high ketones. In other words, ketones are an inverse indicator of what your insulin is. (One of the best ketone devices I know of is Keto-Mojo, as the strips are only $1 each.)

“That was my initial interest in ketones, because it provided that immediate marker of what insulin is, even in a way that glucose cannot. You can have normal glucose levels and have insulin be elevated. If you’re insulin-resistant, you just need more insulin to keep your glucose normal, so you can’t rely on glucose.

In a way, ketones then become more sensitive as a marker, a surrogate for insulin, than even glucose is. Over time, if someone’s had their insulin levels in control for a sufficient period, their liver is basically burning fat at such a high rate that it’s burning more fat than it needs, and so the body has this very kind of clever release or exhaust valve, which is the production of ketones,” Bikman says.

“We have to account for how energy is consumed, how it is used in the form of creating ATP or just body heat — even that’s relevant in ketosis — but then third, for lack of a better word, this energy wasting, because ketones provide this kind of exhaust valve where the body is burning fat so high that it has more than it needs, and it just starts moving it out of the body, in the breath and in the urine.

That needs to be considered, or at least acknowledged … Once again, insulin dictates what the body does with the energy that it has, including producing ketones and having them basically be wasted from the body.”

When and What to Eat When Exercising

Clearly, your diet is far more important than exercise when it comes to controlling your insulin and overall health. That said, I don’t think you can achieve optimal health unless you integrate exercise. The practical question is, “What and when should you eat when you exercise?” My conclusion is that protein is a necessary component of a post-workout meal, and that it’s best to exercise in a fasted state. Bikman agrees, saying:

“With regards to protein, it is without a doubt relevant to someone doing endurance or resistance exercise. You need to make sure you get enough protein. But it appears to be no magic window with that. Basically, you don’t have to get it 45 minutes or an hour after your workout. Essentially, within a 24-hour window, if you’ve eaten sufficient protein, then you’re okay.

Now, with regards to carbohydrate, there was a very neat study done with college students, where they had them exercise and then their next meal was a carbohydrate-rich meal in one group. In the other group, they fasted through that next meal … The group that ate the high-carb diet … did not have an improvement in insulin sensitivity.

By ending their exercise and then having the next meal be a high-carb meal, that undid the improvements in insulin sensitivity from the exercise itself. That has ramifications, because so often someone gets done exercising and they reward themselves with something like juice at some smoothie joint, or they indulge themselves.

They treat themselves with some carbohydrates thinking, ‘I spent it, so I need to eat it.’ What a shame. They are directly preventing some of the insulin-sensitizing benefit of the exercise, because of what they ate …

Like you, I prefer to exercise fasted … I don’t like having something in my gut when I’m trying to push my blood to my muscles … That blood has to come from the gut.

You basically are creating this little war, this hemodynamic war where during exercise and yet having eaten something, your body is thinking, ‘Wait a minute. I need to be sending blood into my guts to help move this food through the intestines and digest it. But now, my muscles are active, so I’ve got to push the blood to my muscles.’

You’re creating this split, forcing the body to prioritize where the blood wants to go. But if you leave the food in the gut, that’s going to start to develop some gastrointestinal discomfort.”

The Importance of Leucine Post-Exercise

One of the most important protein sources when you’re exercising is the amino acid leucine. Interestingly, and paradoxically, leucine actually activates autophagy, even though it also activates mTOR, which logically says would result in autophagy being inhibited. This paradox likely has to do with the fact that leucine is ketogenic, meaning it can turn into a ketone, and ketones activate autophagy.

Leucine is so effective for muscle building, research cited by Bikman shows just 5 grams of leucine is enough to maximize muscle protein synthesis in people on an otherwise protein-deficient diet. When it comes to leucine supplements, hydroxymethylbutyrate (HBM) is a breakdown product of leucine that you can take. However, it’s more expensive, and according to Bikman’s reading of the literature, it has no added benefits over leucine itself.

“Just leave it on the store shelf. Don’t spend that higher amount. It is more money than leucine. Just stick with the leucine,” he says. “Leucine is one of the so-called ketogenic amino acids. It can, in fact, take that carbon skeleton of the leucine and turn it into a ketone.

Some amino acids are referred to as glycolytic, where they can come in and basically turn into alanine. They can readily turn into glucose as needed. Leucine is one of the ketogenic ones, [which] can turn into ketones, beta-hydroxybutyrate in particular. I’d say that if there’s any benefit to HMB, you’re going to get that anyway, because the leucine is going to become HMB.”

Collagen Does Not Count as a Protein Source

As a general rule, to optimize mTOR, you’ll want to restrict your protein intake to about 0.5 grams of protein per pound of lean body mass (not total body weight), or 1 gram of protein per kilo of lean mass. The elderly may need up to 25 percent more.

When calculating your protein intake, keep in mind you do not need to include collagen in your calculations, as it does not have the full complement of amino acids to be considered a complete protein. Collagen — provided it’s a high-quality, organic grass fed source — is important for the health of your connective tissue, and will help prevent injuries. So, while you don’t want to have excess protein, you almost get a free pass with collagen.

“Collagen [contains] a different bunch of amino acids,” Bikman explains. “One in particular is hydroxyproline, one of the main building blocks for collagen in the body. I’ve had people kind of challenge that idea and say, ‘Well, but when you eat these proteins, even in the form of collagen, it will degrade into the amino acids. The body will just kind of choose whatever amino acids it wants to put back together to make whatever proteins it wants.’

That’s generally true. There is a very neat rat study. We just have to assume the same thing holds in humans. I think it’s a safe assumption here. They had the rats eat a radio-labelled hydroxyproline, so they could basically follow that hydroxyproline around.

Sure enough, it went to the skin and to the connective tissue. They could detect where it was enriched. It was all this connective tissue-rich or collagen-rich tissue in the body. I am an advocate of collagen. The evidence supports it. It’s especially relevant to someone who adheres to a low-carb diet. Vitamin C is called C for collagen.

What’s important is that if you’re eating less vitamin C, it’s comforting to know that you’re fulfilling that need essentially by getting not only the collagen itself from the meat that you’re eating, that connective tissue and that hydroxyproline and the other amino acids relevant to collagen, but also carnitine, which is relevant to the function and production of collagen within the body.

Even a low-carb person, who’s avoiding vitamin C, can rest assured their joints and connective tissues are going to be OK, because they’re actually directly eating what they need rather than having the body make what they need with the help of vitamin C.”


          Infographic Of The Day: American Lifespans In Decline       Comment   Translate Page      

Not all Americans are seeing their lifespans in decline, though the overall life expectancy is in decline. Obesity is the biggest single factor behind this shift.

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          Infographic Of The Day: 20 Common Metal Alloys And What They Are Made Of       Comment   Translate Page      

Have you ever wondered where metal comes from, how humans figured out how to make brass, or why rose gold is just a slightly different hue? We've created a comprehensive chart of metals and their alloys: A list of common metal alloys like this can help us answer many questions we have about our metal tools, our everyday lives, and our universe!

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          Mozambique: Responding Organisations Presence as of 11 Apr 2019      Comment   Translate Page      
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          Tonos de comunicación en Redes Sociales #infografia #infographic #socialmedia      Comment   Translate Page      

Hola: Una infografía sobre los tonos de comunicación en Redes Sociales. Vía Juan Carlos Mejía Un saludo

The post Tonos de comunicación en Redes Sociales #infografia #infographic #socialmedia appeared first on TICs y Formación.


          A 5-Step Strategy to Align Training with Business Goals [Infographic]      Comment   Translate Page      
A 5-Step Strategy to Align Training with Business Goals [Infographic]Can you achieve business goals by aligning them with training? A 5-step strategy on aligning training to business goals revealed in this infographic.
          Integrating Text Messaging into the Entire Hotel Guest Experience      Comment   Translate Page      

Engaged guests are happier guests. In this infographic, we illustrate ways hotels can integrate mobile and text messaging to deliver a higher level of service throughout the guest journey.



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          The Ice Bowl 50-year Anniversary #infographic      Comment   Translate Page      
The Ice Bowl 50-year Anniversary

It would have been a great game if it had been played on a sweltering September afternoon or on a crisp autumn day in November or even indoors, if there were domed football stadiums in 1967.That year, the NFL Championship Game pitted Vince Lombardi’s proud but aging Green Bay Packers, seeking an unprecedented third consecutive title, against Tom Landry’s Dallas Cowboys, an ascending team out for revenge after losing narrowly to the Packers in the ’66 championship game.

          Christmas trees: Festive, fun and flammable #infographic      Comment   Translate Page      
Christmas trees: Festive, fun and flammable

Christmas trees light up our homes, but they also pose a fire hazard. Here are some stats and tips about holiday fire safety.Bournemouth & Poole Tourism is proud to present its popular winter attraction – magical, mystical, memorable and much more! The South’s most celebrated coastal town continues to build its reputation as the ultimate year-round destination with the return of the Bournemouth Christmas Tree Wonderland.

          Why Land Rights Matter #infographic      Comment   Translate Page      
Why Land Rights Matter

USAID designs, tests, and evaluates innovative and cost-effective land and resource governance and property rights approaches around the globe that can be adapted and scaled. In this infographic, we worked with them to showcase just why land rights matter and what U SAID’s land tenure programs show by the numbers. With evidence suggesting that understanding, clarifying and enforcing land rights can have a powerful impact on all members of society, it’s definitely an issue that more members of society need to be educated on.

          2017 Total Solar Eclipse #infographic      Comment   Translate Page      
2017 Total Solar Eclipse

Look out! The astronomical event of the year is coming August 21, 2017. This will be the first total solar eclipse in the continental U.S. in 38 years, and you’ll have to wait until 2024 for another one. Check out this sweet infographic we made to learn more about the eclipse and the best spots to watch it happen.

          Tier 1 ERP Software insight #infographic      Comment   Translate Page      
Tier 1 ERP Software insight

Top Tier 1 ERP vendors handful of statistics infographic gathers interesting facts about global main ERP competitors. Shown data should help you to make a confident decision while planning your next implementation. The fact is that Microsoft Dynamics is the most frequently short listed ERP solution and over-performs the competition in many ways.

          Can My Dog Have #infographic      Comment   Translate Page      
Can My Dog Have

“Can my dog have [insert “people food” item here]?” We’ve all asked our vet/the internet about sharing with our pups at one point or another. (Who can say no to those eyes?) It can be hard to guess which snacks could be harmful to your furry friend, but hopefully this infographic helps!

          How To Make Whiskey #infographic      Comment   Translate Page      
How To Make Whiskey

we were ready to give ourselves a new challenge. For this infographic, we wanted to visualize a process and push ourselves to create a great project in a much shorter amount of time. Plus we got to make an infographic about one of our favorite hobbies.

          Inside The Millennial Mind The Rapid Rise Of New Generation #infographic      Comment   Translate Page      
Inside The Millennial Mind The Rapid Rise Of New Generation

Everyone seems to be talking about Millennials today. It’s not just because they are the largest generation by population size – though that certainly doesn’t hurt. It’s because we’re all fascinated with them – news coverage, political campaigns, and of course, marketers trying to figure out how to reach them. But beyond their size, what is it about this generation that has everyone so captivated? It’s their unique sense of self (for lack of a better word), their surprisingly optimistic outlook on life (despite the harsh economic realities they face), and their less than traditional approach to life stages.

          The 10 Most Populous U.S. Cities Every Decade Since 1790 #infographic      Comment   Translate Page      
The 10 Most Populous U.S. Cities Every Decade Since 1790

The United States Census began in 1790 during a time of major growth across America. As the country developed and people began to spread out, the government used it to better understand the needs of our nation.

The census has been continually changing over the past 220 years, with new questions being added as time goes on. Over time the census began collecting data on social statistics, taxation, religion, crime the census began it asked questions regarding social issues, taxes, religion, crime, health, housing, and more . The U.S. Government is even currently in debate about whether or not the 2020 census should include a citizenship question.

 When the census first began the United States had a population of just under four million people. Today the most populous city in the country, New York City, has a population more than double that of over 8.1 million people. Has your city ever landed in the top ten most populous cities in the nation during a census? Find out now on this data visualization from LibertyCruise.nyc.

          The State of Higher Education, 2019      Comment   Translate Page      
The infographic above was sampled from the organization Third Way’s assessment of the state of higher education in the United States in 2019: This report examines whether US institutions of higher education are successful in educating and preparing the next generation of workers. Specifically, it looks at three critical measures of success: 1) college completion; […]
          Cómo hacer Serigrafía #infografia #infographic #design      Comment   Translate Page      

Hola: Una infografía sobre cómo hacer Serigrafía. Vía Paredro Un saludo

The post Cómo hacer Serigrafía #infografia #infographic #design appeared first on TICs y Formación.


          10 SCARY THINGS ABOUT SPACE      Comment   Translate Page      

10 Scary Things About Space
By Christopher Warner,
Toptenz, 14 April 2019.

Since the dawn of man (and woman), humankind has gazed longingly at the flickering stars high above in search of meaning, guidance, and inspiration. A gradual progression in science and technology has taught us much about our faraway skies - namely, that it’s cold, dark, and tantalizingly mysterious up there. It’s also scarier than Hell.

Nonetheless, it’s hard not to daydream about the outer limits or simply laugh at Captain Kirk and that space lizard in the worst fight scene ever filmed. Although many elements of the final frontier remain elusive, recent discoveries have revealed an array of terrifying threats that will keep even the bravest star warriors hiding under the covers with the lights on at night.

10. Meteor Showers


Imagine cruising along in your Honda or Chevy GUV (Galactic Utility Vehicle) blasting sound waves on the ol’ satellite when suddenly out of nowhere - BLAMMO - you’re blindsided by a huge boulder. Not only is your insurance rate going to skyrocket, but the nearest space side assistance is billions of miles away. Bummer.

Although this scenario may seem like a sci-fi nightmare, a similar occurrence actually occurred on planet earth in 2013 after a meteorite exploded over the Ural mountains in Russia. By the time the dust settled, over 400 people had been injured, underscoring the disturbing reality that cascading debris can strike without warning.

Fortunately, most large falling objects burn up while traveling through the earth’s atmosphere. Space travelers in the future, however, will have to dodge a spate of other potential hazards, including meteors, comets, and asteroids.

9. Black Holes


Q: What traps light, warps time, and operates on a colossal scale but yet can’t be seen? A: Black Holes. True to its enigmatic label, black holes have been mythically confounding ever since Albert Einstein first introduced the notion with his general theory of relativity in 1916.

Recently, astronomers took the first image ever of a black hole via the Event Horizon Telescope, a network of eight linked telescopes around the world. Although many questions still remain unanswered, black holes are characterized by the way they affect nearby debris, stars, and galaxies - and typically form out of the death of a large star called a supernova (more on that that later). Unlike a planet or star, a black hole doesn’t have a surface but rather occupies a region where matter has collapsed on itself. The amount of concentrated mass is such that nothing can escape its gravitational pull - not even light - and certainly not an astronaut who makes a disastrous wrong turn while lost in space.

Black holes exist in many different sizes, and similar to tornadoes, they tend to move around at high speeds, leaving a trail of destruction in its wake. Even a small one in our Solar System would be catastrophic, tossing planets out of orbit and ripping the sun to shreds. Although intrepid explorers will be tempted to visit these dark voids, nothing so far has ever survived a trip to a black hole.

8. Solar Flares


Our sun is a glorious, awe-inspiring star that provides warmth, light and the necessary temperature for precious life to exist. It’s also steadily expanding - and will someday completely destroy earth, torching our beloved planet like a marshmallow that’s been left too long around a campfire. Fortunately, that won’t happen for billions of years, but in the meantime, solar flares are capable of inflicting tremendous damage with little or no warning.

A solar flare is a violent eruption that occurs when stored energy on the sun is suddenly released. This produces another one of those ridiculous hotter-than-Hell numbers, releasing a flash of radiation across the electromagnetic spectrum.

Scientists classify solar flares according to their brightness and in relation to x-ray wavelengths. The largest of categories, X-class flares, are large, disruptive events that can severely damage satellites, wipe out power grids, and basically relegate all “smart” technology to stupid pieces of crap.

7. Eridanus Supervoid


First of all, stop your juvenile snickering. No, this isn’t slang for an epic bowel movement or anything of the sordid kind. The Eridanus Supervoid is believed to be a massive empty section located in the Eridanus Constellation just south of Orion. However, what makes this discovery so intriguing is that it’s not only the largest structure ever observed in the Universe, but it’s missing about 10,000 galaxies - or around 20 percent less matter than other regions. As a result, the oddity could possibly contain an “alternative reality” within this ominous patch of sky.

In 2004, cosmologists at University of Hawaii observed a span stretching 1.8 billion light-years across and located about 3 billion light-years away (1 light year = 5.88 trillion miles). They identified a large Cold Spot on the Cosmic Microwave Background (CMB), a map of the radiation left over from the Big Bang, providing a critical tool to study the origin and development of the Universe at cosmic timescales.

The startling revelation presented a perplexing conundrum: the enormity of the cold spot doesn’t align with our current understanding of how the Universe evolved. While it’s not uncommon to find a few small warm and cold patches on the CMB, cold patches of this magnitude are a head-scratching anomaly. According to one report, it’s “too big to exist.”

6. Fermi’s Paradox


In 1942, an Italian-American physicist named Enrico Fermi led an all-star team of scientists to build the world’s first nuclear reactor. This monumental effort was part of the Manhattan Project, a top-secret U.S. government operation that produced the atomic bomb. Afterward, Fermi shifted his attention and extraordinary acumen on solving another complex subject: why haven’t we detected any other alien civilization despite the billions upon billions of other Earth-type planets that most likely exist?

The theory, which came to be known as “Fermi’s Paradox,” posits how the high probability of extraterrestrial life is contradictory to the lack of fact-based, demonstrable evidence supporting it. Naturally, this school of thought discounts the myriad of claims made by people who have allegedly witnessed UFOs or experienced alien encounters - not to mention phenomenons such as Crop Circles and Cargo Cult Theory.

While it’s tough to argue with a genius of Fermi’s stature (especially with our own limited, reptilian brains), we’re left wondering if it’s more frightening that we’re all alone or that hostile life forms are waiting to devour us like a Great White Shark munching seal snacks. Either way, it’s best to keep that aforementioned light on at night.

5. HyperNova


Many subjects dealing with the cosmos involve an impossible-to-fathom number. A hypernova is one of them. In this instance, the astronomical figure relates to the excessive amount of heat and energy generated from an explosion. But first, let’s review what is known about these fascinating wonders.

Novas are relatively small eruptions that occur in double star systems. When a white dwarf’s gravity pulls material away from a companion star, gas piles up and eventually becomes dense enough to ignite in a spark of nuclear fusion. Next, the Supernova, usually marks the death of a large star and the formation of a neutron star. The heat of a supernova can reach 120 million degrees - a temperature five times that of a nuclear blast.

Finally, a hypernova is an ultra-energetic supernova marking the birth of black holes and the release of intense gamma-ray bursts (GRBs), the most energetic form of light. As the mightiest of the Nova family, hypernovae are 5 to 50 times more energetic than a supernova. Additionally, for sake of completion, “Champagne Supernova“ is a song by the mega pop band Oasis, featuring lyrics of which scientists have yet to decipher the meaning…

4. We’re really, really, really small…


Although mother earth appears to be a gigantic sphere of bottomless oceans and endless roads, we’re relatively puny compared to other planets. How small? In terms of relative scale, Jupiter is 2.5 times larger than all the rest of the planets in the Solar System combined. But if you really want to feel minuscule, look no further than our sun - that big fiery 10,000-degree inferno 93 million miles away.

The Sun’s diameter is 109 times bigger than the rock we call home and is so large that 1,300,000 planet Earths could fit inside of it. While the luminous ball appears to be the largest star in the sky, that’s only because it’s the closest. The #1 star in the universe is the gargantuan UY Scuti, a Red Supergiant with a radius around 1,700 times larger than our sun.

But don’t despair, Earthlings. At least now you know how a ladybug feels, clinging to a thin blade of grass.

3. Rogue Planets


These wandering vagabonds (also known as nomad planets, unbound planets, orphan planets, starless planets, etc.) are objects with enough mass to qualify as planets but orbit a galactic center directly. The Universe, despite its vast expanse, consists of a jam-packed arena of activity that often resembles a well-choreographed dance. But a rogue planet disrupts this flow, stumbling recklessly to the beat of its own rhythmless hum while bumping into other cosmic bodies like a drunken ballerina.

Scientists believe rogue planets may have have been ejected from a previous planetary system or have never been gravitationally bound to another body such as a star. Furthermore, our galaxy (aka the Milky Way) alone may have billions of them.

Interestingly, some rogue planets feature a molten core, which combined with an insulated, cold exterior, could possess subterranean oceans that support life. A team of petrologists from Rice University recently theorized that a rogue planet the size of Mars possibly collided with earth 4.4 billion years ago, and could very well have planted the seeds of life while creating enough debris that later developed into our moon.

2. Space Junk


Ever since the start of the space race, man-made objects have been piling up in what has been politely termed “orbital debris.” But that’s being a little too kind. Let’s just call it what it really is: space junk. A wide range of discarded litter now includes thousands of metal fragments, cameras, spent rocket boosters, and even a complete 1958 U.S. satellite (Vanguard-1) that’s currently the oldest artificial hunk of metal still in orbit.

This overflowing galactic garbage, not unlike our polluted oceans, is rapidly nearing a critical juncture; the consequences could be detrimental for both astronauts and those below running for cover from the falling rubbish. There are currently over 1,700  satellites in operation, yet represents less than 10 percent of debris large enough to track from the ground. An obscene amount of smaller objects could also cause serious damage - and sadly, the number will only to continue to climb.

In just one single action from 2007, China destroyed a decommissioned weather satellite during one of its weapons tests, smashing the object into over 150,000 pieces. However, any attempts to clean up spiraling mess could present even more problems in terms of national security (surveillance equipment) and/or result in conflicts over territorial rights. In short, we’re doomed.

1. Zombie Stars


Just when you think we couldn’t be inundated any more movies, TV shows, and books about bloodsuckers and the undead, the science community has joined the fray with “Zombie Stars.”  Really? What’s next brainiacs, a Frankenplanet? Never mind.

As one might guess, a zombie star is something that won’t die. Ever. The monstrous explosion from a supernova typically glows brightly for a while before the dying star is obliterated into space dust. That is unless, for reasons that have yet to be determined, the star manages to avoid death. Adding to the horror show, the zombie star can become a vampire star by sucking fuel and energy from a nearby star to revive itself.

The most famous zombie (for scientists, anyway) is known as iPTF14hls. The star first appeared in 1954 and was thought to have died over a half century ago - but a discovery in 2014 revealed it’s still alive with no plans of retiring. According to the renowned astronomer, Iair Arcavi, a NASA Einstein Postdoctoral Fellow at the University of California, Santa Barbara (UCSB) and the Las Cumbres Observatory, the star’s inexplicable behavior is the “the biggest puzzle I’ve encountered.”

Yikes. If he’s stumped, folks, all we can do is lock the doors to the space station and hope for the best.

Top image: Artist’s impression of dust formation around a supernova explosion. Credit: ESO/M. Kornmesser.

[Source: Toptenz. Top image added.]

          Tips to Start a Freelance Business      Comment   Translate Page      

freelance

How to start a successful freelance business?

One of the widely popular types of employment nowadays is freelance because it allows organizing one’s schedule and simply being your own boss. Those who are willing to start such business, probably already know about all the perks of this carrier. Here are simple steps to take for launching an impressive carrier.

  1. Know What to Achieve

It is better to see and visualize a final goal first of all. You need to be sure in what you want to achieve, whether it is a full-time freelancing or using it as a tool to get to another goal. You can even make a plan of the nearest steps and conduct research regarding the industry you are interested in. it is also extremely essential to find what sphere is interesting for you and focus on it. Do you like writing? Maybe you are into graphic design? Plan out what can you do and what services can you deliver.

  1. Find your Place and Audience

There is always competition and people willing to charge less. It is more efficient to narrow down your specialty to one particular sphere and become an incredible professional in it. Find the right niche for your talents and try to define your target customers. Who are these people or companies? Why do you want to work with them? How can you interest them?

  1. Choose your Path

There are many ideas and opportunities for freelancers. Some of them choose to work for companies as writers or put their information on a platform providing freelancers with clients. However, if you want to build a successful freelance business it is better to work on your own, create a website promoting your services and invest in marketing.

  1. Learn about Taxes

Depending on the governmental requirements there are several things you need to do. First of all, get a license or permit to provide services regarding the legal requirements of your place of residence. Prepare yourself to separate business and private expenses and pay tax quarterly. It is better to know all the legal details and consult on what exactly should you do.

  1. Make an Inspiring Portfolio

When launching a website it is necessary to have examples of what you can do, whether it is article or pieces of design. You need to promote yourself and interest clients in what you can deliver. It might also be necessary to give a word about yourself, create a resume. You can use resume services or look at the examples online. Put an emphasis on the actual experience and the innovations you’ve made.

  1. Set reasonable price

Do not go for the lowest rate, there will always be someone charging lower. Base the price for your services on a quality. And do not too much exposure projects.

 

Freelancing might seem challenging at first, but with reasonable planning and organization, you can achieve all your goals.


          Infographic ông Phạm Nhật Vũ và các cựu quan chức bị khởi tố vụ AVG      Comment   Translate Page      
Infographic ông Phạm Nhật Vũ và các cựu quan chức bị khởi tố vụ AVG
Cơ quan cảnh sát điều tra (Bộ Công an) khởi tố vụ án Vi phạm quy định về quản lý và sử dụng vốn đầu tư công gây hậu quả nghiêm trọng xảy ra tại Tổng công ty Viễn thông MobiFone - Bộ Thông tin và Truyền thông cùng các đơn vị liên quan từ tháng 7.2018. Đến nay vụ án này đã có 9 người bị khởi tố, mới nhất là ông Phạm Nhật Vũ.
          Improve UI Theme for Refugees Project      Comment   Translate Page      
HI I would like to improve my Analytics Webapp (single page) written in React which covers the Refugees and Migration topic. The UI Design should be improved and enhanced by slightly changing it. It should be modern and captive with focus on the analytics part, in an infographic style manner. Please come with suggestions and improvements on the UI. But do not make a revolution just minimal changes and improvements (icon, structure). The main part of the site seems to me still a bit empty (see KPI's). Some ideas which we had: - Adding Animated Timeline slider (vertical) - Adding some icons visualizing the refugees and population kpis - Adding additional visualization by mouse hovering in the table cell where you can see the icons... ... Thanks! (Prize: 100)
           Comment on The 50 Best Singers From All Genres & Generations [Infographic] by RALUCA       Comment   Translate Page      
WHERE IS MICHAEL JACKSON???
          Egypt: Consultancy for Graphic designer - Nationals Only      Comment   Translate Page      
Organization: UN Children's Fund
Country: Egypt
Closing date: 18 Apr 2019

UNICEF works in some of the world’s toughest places, to reach the world’s most disadvantaged children. To save their lives. To defend their rights. To help them fulfill their potential.

Across 190 countries and territories, we work for every child, everywhere, every day, to build a better world for everyone.

And we never give up.

METHODOLOGY

Duties will entail regular monitoring, follow-up and supervision of the below mentioned tasks.

ACTIVITIES, DELIVERABLES AND TIMELINES, PLUS BUDGET PER DELIVERABLE

Key Tasks

Expected Outputs

  • Conceptualize and develop Communication products to support communication initiatives and requirements.
  • Work closely with the digital team to create and produce social media/website products.
  • Campaigns concepts/ ideas.
  • Provide design and branding support and implementation for UNICEF Egypt's campaigns.
  • Office Publications.
  • Infographic motion graphics videos
  • Communication products delivered in a timely manner including design and branding of print materials such as posters, rollups, banners, back-drops, pop-ups notebooks, folders, cut-outs and toolkits.
  • Quality social media & website products produced such as posts, GIFs, canvas designs, cover photos and message-targeted infographics/factographs.
  • Deliver a minimum of 3 concepts/ideas for each communication campaign requirement and present it to UNICEF Egypt Communication team to select the best principle.
  • Graphic design assets developed for UNICEF Egypt's campaigns, including but not limited to: End Violence Against Children, Early Childhood Development, CRC, etc.
  • Strong, creative designs and solutions are delivered for reports, fundraising documents, coloring books, brochures, flyers, booklets, and other office publications requested by other sections.
  • Create a wide variety of motion graphics videos, including infographics and animated graphics for use across multiple platforms, including Facebook, YouTube and more.
  • Proposed Payment Schedule:

    Monthly basis, upon delivery of monthly report including a log of major activities and progress, achievements, constraints and recommendations.

    QUALIFICATIONS, SPECIALIZED EXPERIENCE AND ADDITIONAL COMPETENCIES

  • Bachelor's degree preferably in Art, Graphic Design, Communications or related fields.
  • Expert knowledge in graphic design and graphic design software, including but not limited to: Adobe Photoshop, Illustrator, InDesign, After effect and Final Cut Pro.
  • Advanced knowledge in concept and creation of specific graphic design assets, including infographics/factographs (for print and digital), data visualization, animation, and interactive presentations.
  • Strong comprehension of work, standards and practices of UN and other International Government/Humanitarian Organizations.
  • Proven ability to deliver under tight deadlines.
  • CONDITIONS OF WORK

    Work will be undertaken from home, and an iMac will be available to use at UNICEF's office whenever needed.

    NOTE FOR CONSULTANTS AND INDIVIDUAL CONTRACTORS:

    Please submit a financial offer along with your proposal, which contains the following information:

    -Fee for services to be provided based on the deliverables in the Terms of Reference.

    UNICEF has a zero-tolerance policy on conduct that is incompatible with the aims and objectives of the United Nations, including sexual exploitation and abuse, sexual harassment, abuse of authority and discrimination. UNICEF also adheres to strict child safeguarding principles. All selected candidates will, therefore, undergo rigorous reference and background checks, and will be expected to adhere to these standards and principles.

    Remarks: Only shortlisted candidates will be contacted and advance to the next stage of the selection process.


    How to apply:

    UNICEF is committed to diversity and inclusion within its workforce, and encourages qualified female and male candidates from all national, religious and ethnic backgrounds, including persons living with disabilities, to apply to become a part of our organization. To apply, click on the following link http://www.unicef.org/about/employ/?job=521387


              Improve UI Theme for Refugees Project      Comment   Translate Page      
    HI I would like to improve my Analytics Webapp (single page) written in React which covers the Refugees and Migration topic. The UI Design should be improved and enhanced by slightly changing it. It should be modern and captive with focus on the analytics part, in an infographic style manner. Please come with suggestions and improvements on the UI. But do not make a revolution just minimal changes and improvements (icon, structure). The main part of the site seems to me still a bit empty (see KPI's). Some ideas which we had: - Adding Animated Timeline slider (vertical) - Adding some icons visualizing the refugees and population kpis - Adding additional visualization by mouse hovering in the table cell where you can see the icons... ... Thanks! (Prize: 100)
              Infographic Of The Day: American Lifespans In Decline       Comment   Translate Page      

    Not all Americans are seeing their lifespans in decline, though the overall life expectancy is in decline. Obesity is the biggest single factor behind this shift.

    Read more ...




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