Newswise Curated News Channel: National Institutes of Health (NIH)

Study Reveals How Fatty Liver Promotes Colorectal Cancer Spread

Cedars-Sinai — Thu, 11 May 2023 17:40:43 EST

Investigators at Cedars-Sinai Cancer found that fatty liver, a condition closely associated with obesity, promotes the spread of colorectal cancer to the liver. Their study, published today in the peer-reviewed journal Cell Metabolism, details the process at the cellular level and could change the way doctors manage the disease in some patients.

Annual Medicare spending could increase by $2 to $5 billion if Medicare expands coverage for dementia drug lecanemab

University of California, Los Angeles (UCLA), Health Sciences — Thu, 11 May 2023 15:35:00 EST

The anti-dementia medication lecanemab and its ancillary costs could add $2 billion to $5 billion in annual Medicare spending if the Centers for Medicare and Medicaid Services (CMS) revise their coverage decision. Currently, the medication is covered only for patients who are enrolled in clinical trials.

Sleep apnea associated with increased risk for long COVID

NYU Langone Health — Thu, 11 May 2023 15:20:02 EST

Sleep apnea may significantly increase the risk for long COVID in adults, according to a study led by the National Institutes of Health's RECOVER Initiative and supported by NYU Langone Health as home to the effort's Clinical Science Core (CSC).

UC Irvine study shows traffic-related air pollution in Irvine weakens brain function

University of California, Irvine — Thu, 11 May 2023 15:10:42 EST

Researchers from the University of California, Irvine have found that exposure to traffic-related air pollution in Irvine led to memory loss and cognitive decline and triggered neurological pathways associated with the onset of Alzheimer's disease.

Second gene implicated in malaria parasite resistance evolution to chloroquine

Texas Biomedical Research Institute — Thu, 11 May 2023 13:40:17 EST

How malaria parasites evolved to evade a major antimalarial drug has long been thought to involve only one key gene. Now, thanks to a combination of field and lab studies, an international research team has shown a second key gene is also involved in malaria's resistance to the drug chloroquine.

Van Andel Institute, Washington University School of Medicine in St. Louis to lead genome center under $140M NIH initiative

Van Andel Institute — Thu, 11 May 2023 13:10:57 EST

Van Andel Institute's Hui Shen, Ph.D., and Washington University School of Medicine in St. Louis's Ting Wang, Ph.D., will co-lead a collaborative project supported by the Somatic Mosaicism across Human Tissues (SMaHT) Network, a new $140 million National Institutes of Health-led effort to better understand the genetic differences between individual cells and tissues in the body.

UT Southwestern researchers discover mechanism responsible for genome rearrangements

UT Southwestern Medical Center — Thu, 11 May 2023 12:45:46 EST

The goal of every dividing cell is to accurately segregate its genome into two genetically identical daughter cells. However, this process often goes awry and may be responsible for a new class of chromosomal abnormalities found in cancers and congenital disorders, UT Southwestern Medical Center scientists report in a new study. The discovery, published in Nature, sheds light on how cancer cells rapidly evolve genomic changes that fuel their proliferation.

Markey Cancer Center study identifies new treatment target for metastatic cancer

University of Kentucky — Thu, 11 May 2023 09:55:14 EST

A new University of Kentucky Markey Cancer Center study reveals more about changes that happen to cancer cells when they metastasize and identifies a promising target for the treatment of metastatic breast cancer.Metastasis is when cancer cells spread from the primary tumor to surrounding tissues and distant organs in the body and is the primary cause for breast cancer mortality.

Next-generation statistical simulator gives medical and biological researchers a benchmarking tool capable of closely mimicking single-cell and spatial genomics data

University of California, Los Angeles (UCLA), Health Sciences — Thu, 11 May 2023 08:00:00 EST

UCLA researchers have developed an "all-in-one," next-generation statistical simulator capable of assimilating a wide range of information to generate realistic synthetic data and provide a benchmarking tool for medical and biological researchers who use advanced technologies to study diseases and potential therapies.

فهم سرعة اتصال الدماغ

Mayo Clinic — Thu, 11 May 2023 07:00:43 EST

في الغالب كان يُعتقد أن سرعة المعلومات المنقولة ما بين مناطق الدماغ تستقر في بداية المراهقة. لقد وجدت دراسة جديدة في مجلة نيتشر نيوروسينس أجراها باحثو مايو كلينك وزملاؤهم من هولندا أن سرعات نقل المعلومات تستمر في الزيادة حتى بداية البلوغ.

Sleep Apnea, Lack of Deep Sleep Linked to Worse Brain Health

American Academy of Neurology (AAN) — Wed, 10 May 2023 16:00:00 EST

People who have sleep apnea and spend less time in deep sleep may be more likely to have brain biomarkers that have been linked to an increased risk of stroke, Alzheimer's disease and cognitive decline, according to new research published in the May 10, 2023, online issue of Neurology(r), the medical journal of the American Academy of Neurology. The study does not prove that these sleep disturbances cause the changes in the brain, or vice versa. It only shows an association.

Behind the Scenes of a Major Genomic Discovery

Mount Sinai Health System — Wed, 10 May 2023 11:00:00 EST

Eimear Kenny, PhD, had just completed undergrad and was working in her first computational genomics job more than 20 years ago when scientists announced the first (nearly) complete sequencing of the human genome--what was considered at the time to be the fundamental blueprint for all humans. The Human Genome Project aimed to map the entire genome in an effort to accelerate the diagnosis and eventual treatment of common and rare diseases.

Using AI to Predict Cardiac Pumping Performance, Minimizing the Need for Invasive Testing

University of California, San Francisco (UCSF) — Wed, 10 May 2023 11:00:00 EST

In a study publishing May 10 in JAMA Cardiology, senior author and UCSF cardiologist Geoff Tison, MD, MPH, and first author Robert Avram, MD, of the Montreal Heart Institute, set out to determine whether deep neural networks (DNNs), a category of AI algorithm, could be used to predict cardiac pump (contractile) function from standard angiogram videos. They developed and tested a DNN called CathEF, to estimate LVEF from coronary angiograms of the left side of the heart.

Rutgers Experts Aim to Uncover Barriers to Conducting HIV Research in Africa

Wed, 10 May 2023 08:00:41 EST

Rutgers Institute for Health researcher, Dr. Ashley Grosso, receives grant from NIH to conduct study on barriers to HIV research in Africa.

Not all statins are created equal

Wyss Institute for Biologically Inspired Engineering at Harvard University — Tue, 09 May 2023 15:05:20 EST

We've all recently gotten a crash-course in drug repurposing, thanks to near-daily news reports about efforts to identify existing medicines that could help treat COVID-19 in the early phase of the pandemic.

UCI researchers discover new drugs with potential for treating world's leading causes of blindness in age-related and inherited retinal diseases

University of California, Irvine — Mon, 08 May 2023 14:05:48 EST

In a University of California, Irvine-led study, researchers have discovered small-molecule drugs with potential clinical utility in the treatment of age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP).

Mount Sinai Researchers Describe Urgent Need for Data on Quality of Care Offered by Medicare Advantage Plans

Mount Sinai Health System — Mon, 08 May 2023 13:30:58 EST

As Medicare Advantage plans enroll more and more patients with serious illness, it is not clear how well the plans take care of these patients, Mount Sinai researchers say in a Perspective piece published today in the New England Journal of Medicine.

Novel Rutgers COVID Vaccine May Provide Long-Lasting Protection

Rutgers University-New Brunswick — Mon, 08 May 2023 13:20:25 EST

Rutgers team that created the new COVID vaccine aims to partner with a pharmaceutical company to launch human trials.

Researchers develop model for how the brain acquires essential omega-3 fatty acids

University of California, Los Angeles (UCLA), Health Sciences — Mon, 08 May 2023 11:10:53 EST

Researchers have developed a zebrafish model that provides new insight into how the brain acquires essential omega-3 fatty acids, including docosahexaenoic acid (DHA) and linolenic acid (ALA), creating the potential to improve understanding of lipid transport across the blood-brain barrier.

A Key Biological Pathway for Multiple Sclerosis Is Uncovered by Mount Sinai Researchers

Mount Sinai Health System — Mon, 08 May 2023 11:00:00 EST

Findings reveal a previously unknown way in which the brain and immune system talk to each other and may identify a new therapeutic target for MS and other brain disorders.

Research aims to uncover genetic and environmental risk factors of nonalcoholic fatty liver disease

Wayne State University Division of Research — Mon, 21 Aug 2023 14:05:59 EST

A $3 million, five-year award from the National Institute of Environmental Health Sciences of the NIH aims to discover and validate the gene Х heavy metal (GXM) interactions in human livers and to understand their role in nonalcoholic fatty liver disease

Nanozymes drive tumor-specific drug delivery while minimizing toxicity

National Institute of Biomedical Imaging and Bioengineering — Wed, 09 Aug 2023 10:35:16 EST

Nanozymes--artificial enzymes that can carry out pre-determined chemical reactions--could selectively activate a cancer drug within a tumor while minimizing damage to healthy tissue in a mouse model of triple negative breast cancer.

Transcription Factors Contribute to Subtypes of Colorectal Cancers

Johns Hopkins Medicine — Thu, 27 Jul 2023 11:05:15 EST

New research in colorectal cancers directed by investigators at the Johns Hopkins Kimmel Cancer Center suggests that expression of transcription factors -- proteins that help turn specific genes on or off by binding to nearby DNA -- may play a central role in the degree of DNA methylation across the genome, contributing to the development of different subtypes of these cancers. Methylation is a process in which certain chemical groups attach to areas of DNA that guide genes' on/off switches.

Why Ongoing Worker Safety Training Is Critical to Effective Disaster Response

Rutgers University-New Brunswick — Wed, 19 Jul 2023 12:00:51 EST

Rutgers is part of a national network of institutions tasked with ensuring workers have the knowledge and skills to stay safe on the job.

Women treated for breast cancer may age faster than cancer-free women

National Institute of Environmental Health Sciences (NIEHS) — Wed, 19 Jul 2023 10:05:26 EST

Women diagnosed and treated for breast cancer have increased biological aging compared to women who remain free of breast cancer, according to a new study by researchers at the National Institutes of Health and their collaborators. Among women diagnosed with breast cancer, the association with faster biological aging was most pronounced for those who received radiation therapy, while surgery showed no association with biological aging. This finding suggests that developing cancer is not what increases the aging effect.

Proteins Predict Significant Step Toward Development of Diabetes

Pacific Northwest National Laboratory — Thu, 29 Jun 2023 11:00:00 EST

Scientists have taken an important step forward in predicting who will develop Type 1 diabetes months before symptoms appear.

Mount Sinai Institute for Exposomics Research Awarded $8.45 Million Grant to Study Environmental Health

Mount Sinai Health System — Tue, 27 Jun 2023 09:00:35 EST

New five-year award will focus on the effects of environmental exposures on health across the lifespan

UC Irvine receives grant to study lead exposure effects on children's learning, behavior

University of California, Irvine — Wed, 14 Jun 2023 13:30:03 EST

The Program in Public Health at the University of California, Irvine has received a five-year, $2.7 million grant from the National Institute of Environmental Health Sciences to research the connection between low-level lead exposure during pregnancy and early childhood and children's school performance and behavior in Santa Ana, California.

Exposure to "forever chemicals" during pregnancy linked to increased risk of obesity in kids

Brown University — Wed, 07 Jun 2023 20:00:01 EST

The risks of exposure to "forever chemicals" start even before birth, a new study confirms, potentially setting up children for future health issues.

Fetal exposure to PCBs affects hearing health later in life

Beckman Institute for Advanced Science and Technology — Mon, 05 Jun 2023 14:35:48 EST

Researchers at the Beckman Institute for Advanced Science and Technology found that early exposure to an environmental chemical called polychlorinated biphenyls, or PCBs, made it more difficult for mice to recover from sound-related trauma sustained later in life.

Air pollution worsens movement disorder after stroke

Hiroshima University — Wed, 10 May 2023 14:45:30 EST

Air pollution has been shown to have a negative effect on the prognosis of ischemic stroke, or stroke caused by reduced blood flow to the brain, but the exact mechanism is unknown. A team of researchers recently conducted a study to determine whether or not increased inflammation of the brain, also known as neuroinflammation, is the main culprit.

Higher lithium levels in drinking water may raise autism risk

University of California, Los Angeles (UCLA), Health Sciences — Mon, 03 Apr 2023 11:00:00 EST

Pregnant women whose household tap water had higher levels of lithium had a moderately higher risk of their offspring being diagnosed with autism spectrum disorder, researchers reported in JAMA Pediatrics.

Black, Latinx Californians face highest exposure to oil and gas wells

University of California, Berkeley — Fri, 24 Mar 2023 16:25:07 EST

More than 1 million Californians live near active oil or gas wells, potentially exposing them to drilling-related pollution that can contribute to asthma, preterm births and a variety of other health problems.

New Study: Abatacept Therapy Offers Promising Results Treating Juvenile Dermatomyositis

George Washington University — Wed, 08 Mar 2023 12:40:35 EST

Juvenile dermatomyositis, a rare but often severe and chronic systemic autoimmune disease, includes a large number of patients who are treatment resistant, requiring long term immunosuppressive therapy. A small open-label study published in Arthritis and Rheumatology shows promise using a targeted biologic therapy called abatacept to treat such patients.

Exposure to green space linked to reduced risk of postpartum depression

University of California, Irvine — Mon, 06 Mar 2023 12:35:36 EST

In an analysis of more than 415,00 electronic health records of healthy, full-term births in Southern California, a team of researchers led by the University of California, Irvine determined that exposure to green space and tree coverage was associated with a decreased risk of postpartum depression among mothers.

Toxic protein linked to muscular dystrophy and arhinia

National Institute of Environmental Health Sciences (NIEHS) — Fri, 17 Feb 2023 14:00:00 EST

Researchers at the National Institutes of Health and their colleagues have found that a toxic protein made by the body called DUX4 may be the cause of two very different rare genetic disorders. For patients who have facioscapulohumeral muscular dystrophy (FSHD), or a rare facial malformation called arhinia, this research discovery may eventually lead to therapies that can help people with these rare diseases.

PFAS Can Suppress White Blood Cell's Ability to Destroy Invaders

North Carolina State University — Wed, 15 Feb 2023 11:05:15 EST

In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst - the method white blood cells known as neutrophils use to kill invading pathogens.

Clemson scientists identify enzyme that reduces diet-induced obesity in humans

Clemson University — Mon, 30 Jan 2023 08:00:00 EST

Clemson University researchers have identified an enzyme and its products in humans that reduce diet-induced obesity.

Exposure to toxic blue-green algae, exacerbated by climate change, shown to cause liver disease in mouse models

University of California, Irvine — Tue, 20 Dec 2022 18:10:32 EST

Algal blooms or cylindrospermopsin, exacerbated by climate change, shown to have a connection with several adverse health effects.

Molecules found in mucus could prevent cholera infection

Massachusetts Institute of Technology (MIT) — Mon, 12 Dec 2022 16:15:59 EST

MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state.

Wake Forest University School of Medicine Awarded $1.9 Million to Study Biomarkers for Chronic Pain

Wake Forest University School of Medicine — Mon, 14 Aug 2023 13:00:41 EST

Chronic pain can be debilitating and can limit the quality of life for the millions who suffer from it. Unfortunately, treatments to manage chronic pain are often ineffective because the functional changes that accompany a disease are not fully understood. Many patients develop chronic pain after surgery, but unfortunately, it is not yet possible to predict which patients are at risk.

Experts: Chronic pain patients who take opioids need better care & coverage

Michigan Medicine - University of Michigan — Mon, 14 Aug 2023 11:45:36 EST

People with chronic pain who take opioids have trouble finding multimodal pain care; insurance and provider education changes are needed, experts say.

New Community Partnership Model Boosts Inclusion of Participants into HIV Cure-Directed Research

Wistar Institute — Wed, 19 Jul 2023 12:05:09 EST

Scientists have long used community advisory boards to engage communities and provide feedback on studies, but this model has limitations. Now, Wistar Institute researchers are sharing how a more inclusive model for community engagement can lead to deeper insights and greater community participation in HIV research.

People with alcohol use disorder impaired after heavy drinking, despite claims of higher tolerance

University of Chicago Medical Center — Sun, 18 Jun 2023 10:00:00 EST

New research shows that drinkers with alcohol use disorder display the same level of fine motor and cognitive impairment as light drinkers when consuming their usual excessive amount.

New Research Reveals Men Die of Overdose at Two-to-Three Times Greater a Rate Than Women in the United States

Mount Sinai Health System — Wed, 14 Jun 2023 20:00:00 EST

Men were significantly more vulnerable than women to overdose deaths involving opioid and stimulant drugs in 2020-2021, according to a new study analyzing data from across the United States.

Reentry Services May Help Stabilize Substance Use Risks After Mass Prison Release

Fri, 02 Jun 2023 11:00:00 EST

Rutgers Institute for Health researchers found that the risk of overdose and death due to substance use didn't increase after a mass prison release.

New research may explain why, despite "the munchies", frequent cannabis users are leaner than non-users

University of California, Irvine — Thu, 01 Jun 2023 16:05:11 EST

Despite getting "the munchies", people who frequently use cannabis are leaner and less prone to diabetes than those who don't. University of California, Irvine researchers have now uncovered a possible explanation for this paradox - and it's not good news.

Do people who use fentanyl test strips practice more overdose risk reduction behaviors than people who don't?

Ohio State University Wexner Medical Center — Wed, 31 May 2023 16:20:05 EST

Leveraging the HEALing Communities Study infrastructure, researchers are testing whether there is an association between fentanyl test strip use and overdose risk reduction behaviors among people who use drugs over a 28-day observation period. The Stay Safe Study will be in Kentucky, Ohio and New York.

Is vaping a new gateway into further substance use? New national study shows adolescent vapers much likelier to use cannabis and binge drink

Taylor & Francis — Thu, 18 May 2023 18:20:11 EST

A new study of more than 50,000 US adolescents across the country indicates that vaping nicotine is strongly linked with an increased likelihood of high levels use of binge drinking and cannabis usage.

Even Worms Get the Munchies

University of Oregon — Thu, 20 Apr 2023 11:00:00 EST

A study, led by University of Oregon neuroscientist Shawn Lockery, points to worms as a useful tool for understanding more about the many roles that cannabinoids naturally play in the body. And it could help researchers develop better drugs that target this system.

School prevalence of stimulant therapy for ADHD associated with higher rates of prescription stimulant misuse among teens

NIH National Institute on Drug Abuse (NIDA) — Tue, 18 Apr 2023 20:30:34 EST

Researchers have identified a strong association between prevalence of prescription stimulant therapy for attention-deficit/hyperactivity disorder (ADHD) and rates of prescription stimulant misuse (taken in a way other than as directed by a clinician) by students in middle and high schools.

In some US schools, 1 in 4 students report misusing prescription stimulants

University of Michigan — Tue, 18 Apr 2023 11:00:00 EST

U.S. middle and high schools with the most students taking prescription stimulants to treat ADHD also had, overall, the highest percentage of students who misused prescription stimulants within the past year.

E-health reduces patient pain, opioids in clinical study

Washington State University — Mon, 03 Apr 2023 12:05:39 EST

An online "e-health" program helped more people with chronic pain reduce their opioid medications and pain intensity than a control group that had only regular treatment in a recent clinical study.

Multiple substance use disorders may share inherited genetic signature

Washington University in St. Louis — Wed, 22 Mar 2023 12:00:00 EST

New research led by Washington University School of Medicine in St. Louis identifies a common genetic signature that may increase a person's risk of developing substance use disorders. The work eventually could lead to universal therapies to treat multiple substance use disorders and potentially help people diagnosed with more than one.

Cannabis use in adolescent years may create reproductive complications in women, according to a UC Irvine study

University of California, Irvine — Tue, 21 Mar 2023 13:00:43 EST

In a new study, University of California, Irvine researchers found that exposure to the compound tetrahydrocannabinol (THC), a component of cannabis, at a young age could lead to depleted ovarian follicles and matured eggs in adulthood by nearly 50 percent.

Stigma-coping intervention empowers people with HIV and drug use to engage in health, substance use care

Boston University School of Medicine — Mon, 20 Mar 2023 15:45:45 EST

A new study from Boston University Chobanian & Avedisian School of Medicine has found that a brief stigma intervention that specifically targets people with HIV who inject drugs was effective in increasing engagement in substance use care as well as improving their ART adherence.

SJU Expert Available for Comment on Black Balloon Day/Opioid Epidemic

Saint Joseph's University — Mon, 27 Feb 2023 15:45:54 EST

Cocaine Use Disorder Alters Gene Networks of Neuroinflammation and Neurotransmission in Humans

Mount Sinai Health System — Fri, 10 Feb 2023 14:00:00 EST

Analysis reveals similar changes in the brain's functioning in both humans and mouse models

Study First to Show Statewide Cannabis-related Deaths in Florida

Florida Atlantic University — Thu, 09 Feb 2023 08:30:28 EST

There has been a 1,107.01 percent increase in the number of people with medical cannabis cards in Florida (2018 to Jan. 27). One key reason is because many people believe cannabinoids - plant derived, medicinal, and synthetic or chemically engineered - are safe to use. A study shows that 386 people died in Florida as a result of cannabis use; of these, 258 cases were caused by synthetic cannabis. Nearly 88 percent were men; 28 percent of deaths were in those ages 45 to 54, compared to 9 percent in those ages 8 to 24. Nearly 99 percent of individuals using cannabis and synthetic cannabis died from accidents.

Overdose deaths involving buprenorphine did not proportionally increase with new flexibilities in prescribing

NIH National Institute on Drug Abuse (NIDA) — Fri, 20 Jan 2023 17:50:36 EST

The proportion of opioid overdose deaths involving buprenorphine, a medication used to treat opioid use disorder, did not increase in the months after prescribing flexibilities were put in place during the COVID-19 pandemic, according to a new study.

Engineers have adjusted the diesel engine to run properly on rapeseed oil

Scientific Project Lomonosov — Wed, 28 Feb 2024 04:05:43 EST

RUDN engineers adjusted the operation of a diesel engine running on rapeseed oil. Typically, the second fuel reduces engine performance, but the authors explained how to adjust it so that vegetable and diesel fuels come close in performance.

Combating fractional spurs in phase locked loops to improve wireless system performance in Beyond 5G

Tokyo Institute of Technology — Mon, 19 Feb 2024 21:05:08 EST

Two innovative design techniques lead to substantial improvements in performance in fractional-N phase locked loops (PLLs), report scientists from Tokyo Tech.

Road features that predict crash sites identified in new machine-learning model

University of Massachusetts Amherst — Tue, 13 Feb 2024 19:05:01 EST

Issues such as abrupt changes in speed limits and incomplete lane markings are among the most influential factors that can predict road crashes, finds new research by University of Massachusetts Amherst engineers.

Japan's electric vehicle transition by 2035 may be insufficient to combat the climate crisis, but there are solutions

Kyushu University — Wed, 07 Feb 2024 10:05:56 EST

Researchers at Kyushu University have found that Japan's current policy of stopping the sale of gas vehicles by 2035 and transitioning only to hybrids and electric vehicles may be insufficient to reduce the country's CO2 emissions and prevent it from reaching its decarbonization target goals.

Pedestrian injuries from falls versus motor vehicle collisions: are we lacking critical policy and interventions?

Columbia University, Mailman School of Public Health — Wed, 31 Jan 2024 17:05:52 EST

Using Emergency Medical Services (EMS) data, researchers at Columbia University Mailman School of Public Health compared the national burden of pedestrian injuries from motor vehicles to that of pedestrian falls occurring on streets and sidewalks and found that the probability of a pedestrian suffering a severe injury is higher for motor vehicle collisions as compared to falls.

The use of biofuels may reduce black smoke emissions of cars by 90%

University of Malaga — Wed, 31 Jan 2024 12:05:56 EST

The UMA participates in an international study with the Future Power Systems Group of the University of Birmingham (UK) that investigates how to reduce pollutant emissions from vehicles without affecting engine performance.

Lifelong learning will power next generation of autonomous devices

Argonne National Laboratory — Wed, 31 Jan 2024 10:05:11 EST

Argonne researchers address challenges scientists face in developing lifelong learning models for autonomous devices, such as self-driving cars, and recommends design principles going forward.

Vehicle networking environment information sharing based on distributed fountain code

Chinese Academy of Sciences — Wed, 31 Jan 2024 07:40:16 EST

Researchers propose a new motion prediction compensation method, which includes a distributed fountain coding scheme, motion prediction model, and information transmission control algorithm, which reduces channel bandwidth resource consumption and improves transmission efficiency.

Key LiDAR sensor elements for autonomous vehicles are now made with our technology

National Research Council of Science and Technology — Wed, 31 Jan 2024 00:00:11 EST

The Korea Institute of Science and Technology (KIST) announced that a team led by Dr. Myung-Jae Lee at the Post-Silicon Semiconductor Institute has developed a "single-photon avalanche diode (SPAD)" that can identify objects at the mm level based on a 40nm back-illuminated CMOS image sensor process.

Karma Automotive drives forward climate innovation with UC Irvine's RADiCal initiative

University of California, Irvine — Thu, 25 Jan 2024 12:05:17 EST

Irvine, Calif., Jan. 25, 2024 -- University of California, Irvine's Resilience and Adaptation Development in California initiative, which deepens university-industry engagement to drive innovation and answer climate challenges, has entered a strategic partnership with Karma Automotive.

Off-road autonomy: U-M's Automotive Research Center funded with $100 million through 2028

University of Michigan — Wed, 24 Jan 2024 11:05:14 EST

The U.S. Army has extended its long-running relationship with the University of Michigan's Automotive Research Center, reaching a new five-year, agreement of up to $100 million to boost work on autonomous vehicle technologies.

Samsung leads again in U.S. patents while Qualcomm leaps into second place; overall grants dip 3.4%

Digital Science and Research Solutions Ltd — Tue, 09 Jan 2024 04:00:00 EST

New 2023 patent data rankings highlight escalating areas of R&D activity, according to an annual patent study by Digital Science company IFI CLAIMS.

More Range for Electric Vehicle Batteries on the Horizon

Pacific Northwest National Laboratory — Wed, 13 Dec 2023 15:05:04 EST

A seemingly simple shift in lithium-ion battery manufacturing could pay big dividends, improving electric vehicles' ability to store more energy per charge and to withstand more charging cycles.

Free electric vehicle charging at work? It's possible with optimum solar

University of South Australia — Tue, 12 Dec 2023 18:05:52 EST

The global surge in electric vehicle sales has prompted an Australian university to explore how it could offer free or nominal EV charging facilities to staff and students by optimising its solar PV system and minimising workplace electricity costs.

Lawrence Livermore and Bay Area startup demonstrate large-scale, cryo-compressed hydrogen storage system for heavy-duty transportation

Lawrence Livermore National Laboratory — Tue, 12 Dec 2023 12:05:44 EST

Lawrence Livermore National Laboratory (LLNL) and Verne, a San Francisco-based start-up, have demonstrated a cryo-compressed hydrogen storage system of suitable scale for heavy-duty vehicles.

MSU joins Indy Autonomous Challenge, partners with Milan team

Michigan State University — Tue, 05 Dec 2023 12:05:17 EST

Michigan State University is racing into the future by entering into a two-year agreement with Politecnico di Milano in Italy, and the University of Alabama to participate in the Indy Autonomous Challenge.

Workplace culture is very different these days. Find out how different by exploring the "In the Workplace" channel

Newswise — Wed, 29 Nov 2023 12:05:50 EST

The latest articles on occupational medicine, workplace culture, and the labor market are in the "In the Workplace" channel on Newswise.

Despite bumpy rollout and 'polarizing style', Cybertruck stokes anticipation

Cornell University — Wed, 29 Nov 2023 12:05:15 EST

Researchers aim to make cheaper fuel cells a reality

SLAC National Accelerator Laboratory — Mon, 13 Nov 2023 14:05:31 EST

The team reduced the amount of expensive platinum group metals needed to make an effective cell and found a new way to test future fuel cell innovations.

New Study Finds Electric Vehicles Are Driven Less Than Gas Cars

George Washington University — Mon, 06 Nov 2023 10:05:28 EST

One of the largest studies to date finds the current generation of EV owners drive far fewer miles than owners of gas vehicles, translating to lower emissions savings from EVs.

NASA uses ORNL supercomputers to plan smooth landing on Mars

Oak Ridge National Laboratory — Thu, 29 Feb 2024 17:05:51 EST

Since 2019, a team of NASA scientists and their partners have been using NASA's FUN3D software on supercomputers located at the Department of Energy's Oak Ridge Leadership Computing Facility, or OLCF, to conduct computational fluid dynamics, or CFD, simulations of a human-scale Mars lander. The team's ongoing research project is a first step in determining how to safely land a vehicle with humans onboard onto the surface of Mars.

CyberShake study uses Summit supercomputer to investigate earthquake hazards

Oak Ridge National Laboratory — Mon, 12 Feb 2024 13:05:21 EST

Researchers at the Statewide California Earthquake Center, or SCEC, are unraveling the mysteries of earthquakes by using physics-based computational models running on high-performance computing systems at the Department of Energy's Oak Ridge National Laboratory. The team's findings will provide a better understanding of seismic hazards in the Golden State.

Argonne training program alumni find success in extreme-scale computing

Argonne National Laboratory — Mon, 12 Feb 2024 10:05:35 EST

Past attendees of the annual Argonne Training Program on Extreme-Scale Computing are thriving in careers across the field of high performance computing.

Direct View of Tantalum Oxidation that Impedes Qubit Coherence

Brookhaven National Laboratory — Mon, 05 Feb 2024 10:05:57 EST

Scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and DOE's Pacific Northwest National Laboratory (PNNL) have used a combination of scanning transmission electron microscopy (STEM) and computational modeling to get a closer look and deeper understanding of tantalum oxide.

UC Irvine scientists make breakthrough in quantum materials research

University of California, Irvine — Wed, 31 Jan 2024 11:05:30 EST

Irvine, Calif., Jan. 31, 2024 -- Researchers at the University of California, Irvine and Los Alamos National Laboratory, publishing in the latest issue of Nature Communications, describe the discovery of a new method that transforms everyday materials like glass into materials scientists can use to make quantum computers.

Bringing supercomputers and experiments together to accelerate discoveries

Argonne National Laboratory — Tue, 30 Jan 2024 16:40:46 EST

Through its Nexus effort, Argonne National Laboratory is working to closely integrate supercomputers with experiments to help researchers keep pace with the ever-increasing influx of scientific data.

Researchers Craft New Way to Make High-Temperature Superconductors - With a Twist

Rutgers University-New Brunswick — Tue, 30 Jan 2024 11:05:01 EST

An international team that includes Rutgers University-New Brunswick scientists has developed a new method to make and manipulate a widely studied class of high-temperature superconductors.

Chemists use the blockchain to simulate over 4 billion chemical reactions essential to the origins of life

Cell Press — Wed, 24 Jan 2024 13:05:05 EST

Cryptocurrency is usually "mined" through the blockchain by asking a computer to perform a complicated mathematical problem in exchange for tokens of cryptocurrency.

New candidate for universal memory is fast, low-power, stable and long-lasting

Stanford University — Mon, 22 Jan 2024 16:05:26 EST

We are tasking our computers with processing ever-increasing amounts of data to speed up drug discovery, improve weather and climate predictions, train artificial intelligence, and much more.

10 researchers receive Argonne Postdoctoral Performance Awards

Argonne National Laboratory — Thu, 18 Jan 2024 10:15:02 EST

10 postdoctoral researchers at the U.S. Department of Energy's (DOE) Argonne National Laboratory were recently recognized at the laboratory's 2023 Postdoctoral Performance Awards, which were presented in a ceremony on Nov. 9.

Using berry phase monopole engineering for high-temperature spintronic devices

Tokyo Institute of Technology — Fri, 05 Jan 2024 13:05:59 EST

Spintronic devices are electronic devices that utilize the spin of electrons (an intrinsic form of angular momentum possessed by the electron) to achieve high-speed processing and low-cost data storage. In this regard, spin-transfer torque is a key phenomenon that enables ultrafast and low-power spintronic devices.

Researchers create first functional semiconductor made from graphene

Georgia Institute of Technology — Wed, 03 Jan 2024 11:00:20 EST

Researchers at the Georgia Institute of Technology have created the world's first functional semiconductor made from graphene, a single sheet of carbon atoms held together by the strongest bonds known. The breakthrough throws open the door to a new way of doing electronics. Video summary: https://www.youtube.com/watch?v=gWUX2OTqkEo

Cosmic lights in the forest

University of Texas at Austin (UT Austin) — Wed, 20 Dec 2023 12:05:26 EST

Like a celestial beacon, distant quasars make the brightest light in the universe. They emit more light than our entire Milky Way galaxy. The light comes from matter ripped apart as it is swallowed by a supermassive black hole.

Computational scientists generate molecular datasets at extreme scale

Oak Ridge National Laboratory — Wed, 20 Dec 2023 11:05:40 EST

A team of computational scientists at the Department of Energy's Oak Ridge National Laboratory has generated and released datasets of unprecedented scale that provide the ultraviolet visible spectral properties of over 10 million organic molecules.

Theta supercomputer set to retire: A look back at its impact on science at Argonne and beyond

Argonne National Laboratory — Wed, 20 Dec 2023 11:05:19 EST

Argonne National Laboratory's Theta supercomputer will be retired at the end of 2023, ending a productive run of enabling scientific breakthroughs in areas ranging from materials discovery to supernova simulations.

Large sequence models for sequential decision-making

Higher Education Press — Fri, 15 Dec 2023 14:05:19 EST

Transformer architectures have facilitated the development of large-scale and general-purpose sequence models for prediction tasks in natural language processing and computer vision, e.g., GPT-3 and Swin Transformer.

Custom software speeds up, stabilizes high-profile ocean model

Oak Ridge National Laboratory — Thu, 14 Dec 2023 16:05:40 EST

Most modern ocean models focus on two categories of waves: a barotropic system, which has a fast wave propagation speed, and a baroclinic system, which has a slow wave propagation speed. To help address the challenge of simulating these two modes simultaneously, a team from DOE's Oak Ridge, Los Alamos and Sandia National Laboratories has developed a new solver algorithm that reduces the total run time of the Model for Prediction Across Scales-Ocean, or MPAS-Ocean, E3SM's ocean circulation model, by 45%.

The A+ Team Tackles AI and Quantum Computing Hardware

Thomas Jefferson National Accelerator Facility — Wed, 13 Dec 2023 16:05:01 EST

A multidisciplinary team led by Jefferson Lab and including imec, NY CREATES, and Cornell University has been selected by DOE to advance a superconducting approach to advanced computer chip technology.

'Tis the season to get vaccinated: How to stay healthy through the holidays

Michigan Medicine - University of Michigan — Wed, 13 Dec 2023 13:05:02 EST

With virus cases rising and the holidays nigh, three expert from University of Michigan Health give their top 12 tips for avoiding or reducing the impact of COVID-19, flu, RSV, pneumonia and whooping cough in adults and kids.

The Evolution and Future of High Performance Computing

Hong Kong Institute for Advanced Study, City University of Hong Kong — Thu, 07 Dec 2023 21:30:06 EST

High performance computing (HPC) stands at the forefront of scientific discovery and commercial innovation, yielding significant economic benefits.

Short On Time? A 15-minute Workout May Help Boost Your Immune System

American Physiological Society (APS) — Fri, 05 Apr 2024 11:30:00 EST

Exercising at moderate intensity for just 15 minutes may be all that is needed to boost immunity by increasing levels of natural killer (NK) cells. Researchers will present their work this week at the American Physiology Summit in Long Beach, California.

UTSW discovers protective 'acid wall' formed by cancer cells

UT Southwestern Medical Center — Mon, 01 Apr 2024 12:05:40 EST

Cancer cells release a significantly more concentrated level of acid than previously known, forming an "acid wall" that could deter immune cells from attacking tumors, UT Southwestern Medical Center scientists show in a new study.

Scientists discover a key quality-control mechanism in DNA replication

Perelman School of Medicine at the University of Pennsylvania — Fri, 29 Mar 2024 11:00:00 EST

DNA replication--which happens when cells divide--is one of the most important processes in all living organisms. In a landmark finding, published today in Cell, scientists identified a multi-protein "machine" in cells that helps govern the pausing or stopping of DNA replication to ensure its smooth progress.

Cell Division Quality Control 'Stopwatch' Uncovered

University of California San Diego — Thu, 28 Mar 2024 14:00:00 EST

UC San Diego biologists have uncovered a quality control timing mechanism tied to cell division. The "stopwatch" function keeps track of mitosis and acts as a protective measure when the process takes too long, preventing the formation of cancerous cells.

Research Demonstrates that Cells Multitask in Bacterial Biofilms

Environmental Molecular Sciences Laboratory - EMSL — Tue, 26 Mar 2024 19:05:39 EST

A team of scientists led an experimental study to determine the relationships between subpopulations of cells within the biofilm of a model microbe, revealing new insights regarding their potential.

Genetically engineered dendritic cells enhance the power of immunotherapy against lung cancer

University of California, Los Angeles (UCLA), Health Sciences — Tue, 26 Mar 2024 10:05:46 EST

The results of a UCLA study suggest that using CXCL9 and CXCL10-producing dendritic cells alongside immunotherapy can be a promising strategy to overcome treatment resistance and improve clinical outcomes for patients with non-small cell lung cancer.

UC Irvine-led study unlocks the secrets of birth defect origins

University of California, Irvine — Thu, 21 Mar 2024 15:05:25 EST

Irvine, Calif., March 21, 2024 - A new study led by the University of California, Irvine has revealed a potential shift in our basic knowledge of the origins of birth defects, which affect about 3 percent of babies born in the United States each year.

First Skeleton-Wide Study of Blood Cell Formation Yields Surprising Findings

Cincinnati Children's Hospital Medical Center — Wed, 20 Mar 2024 12:00:38 EST

Imagine being able to count the different types of blood cells being formed inside the tiny bones of a mouse and pinpointing the strings and clusters of cells within the bone marrow that are responsible for producing specific types of blood cells.

Role in mitochondrial metabolism paints more complete picture of MCL-1 function

St. Jude Children's Research Hospital — Mon, 18 Mar 2024 15:05:38 EST

Scientists at St. Jude Children's Research Hospital have uncovered a metabolic role for cell-survival protein MCL-1, potentially explaining previous clinical trial setbacks.

WashU engineers manage a first: measuring pH in cell condensates

Washington University in St. Louis — Mon, 18 Mar 2024 12:05:49 EST

In a first for the condensate field, researchers from the McKelvey School of Engineering at Washington University in St. Louis, figured out how nucleolar sub-structures are assembled.

We Now Know Why Killer T Cells Lose Energy Inside of Solid Tumors

University of North Carolina School of Medicine — Fri, 15 Mar 2024 11:05:40 EST

Researchers at the UNC School of Medicine have found that a metabolic enzyme called Acetyl-CoA Carboxylase causes T cells to store fat when they are in solid tumors, rather than burning fat for energy.

Nobel Laureate and NASA Astronaut to Speak at American Physiology Summit

American Physiological Society (APS) — Fri, 15 Mar 2024 07:00:27 EST

Nobel Laureate Brian Kobilka, MD, and NASA Astronaut Jessica Meir, PhD, are among the highlighted speakers who will attend the American Physiology Summit, the American Physiological Society's (APS) flagship annual meeting.

Modulation of cellular recycling by calcium ion dynamics across cellular compartments

Chinese Academy of Sciences — Tue, 12 Mar 2024 08:05:09 EST

This study discovers that upon induction of different autophagy processes, mitochondria immediately import calcium and calcium concentrations at the ER membrane start to fluctuate. The major calcium import channel in the inner mitochondrial membrane, mitochondrial calcium uniporter (MCU), is required for mitophagy-inducer-initiated mitochondrial calcium uptake. Inhibiting MCU accelerates mitophagy. In neurons derived from a Parkinson's patient, mitophagy-inducer-triggered mitochondrial calcium influx is faster, which may slow the ensuing mitophagy.

Lung cancer treatment shows promise in tumor models

UT Southwestern Medical Center — Mon, 11 Mar 2024 11:05:35 EST

A molecule has demonstrated its ability to kill tumor cells and incite an immune response in preclinical models of small cell lung cancer (SCLC), according to UT Southwestern Medical Center researchers. The findings, published in Nature Communications, could lead to more successful treatments for SCLC, one of the leading causes of cancer-related deaths in the U.S.

Iron Restriction Keeps Blood Stem Cells Young

Albert Einstein College of Medicine — Fri, 08 Mar 2024 11:05:17 EST

As we age, our hematopoietic (blood-forming) stem cells (HSCs) become less able to produce new red and white blood cells and other vital blood components--contributing to chronic inflammation and accelerating the onset of blood cancers and degenerative diseases.

Slu's Tim Randolph Honored for Discovery of New Diagnostics for Sickle Cell Disease in Underdeveloped Countries

Saint Louis University — Thu, 07 Mar 2024 09:05:07 EST

Researcher Tim Randolph, Ph.D., professor of clinical health sciences at Saint Louis University, has been named a Senior Member of the National Academy of Inventors.

Dive into the future of molecular life sciences at #DiscoverBMB 2024

American Society for Biochemistry and Molecular Biology (ASBMB) — Tue, 05 Mar 2024 09:00:40 EST

Discover BMB, the annual meeting of the American Society for Biochemistry and Molecular Biology will be held March 23-26 in San Antonio. Secure your front-row seat to cutting-edge findings, approaches and technologies in the biological sciences by registering for a complimentary press pass to attend in person or to access press materials electronically.

Simmons Cancer Center awarded nearly $19 million in CPRIT funding

UT Southwestern Medical Center — Mon, 04 Mar 2024 11:05:30 EST

Nine scientists and physicians in the Harold C. Simmons Comprehensive Cancer Center at UT Southwestern Medical Center have been awarded nearly $13 million in grants from the Cancer Prevention and Research Institute of Texas (CPRIT) to support research and prevention efforts on a wide range of cancer issues. UTSW received another $6 million for recruitment efforts.

Cell Division, DNA Repair, and Cancer Progression Closely Tied to CDK9 Dysfunction

Sbarro Health Research Organization (SHRO) — Sun, 03 Mar 2024 20:00:00 EST

Researchers describe a newly-observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth.

Children's Hospital Los Angeles Awarded $6 Million from CIRM to Advance CAR T-Cell Therapies in Children with Recurring Solid Tumors

Children's Hospital Los Angeles — Thu, 29 Feb 2024 18:05:22 EST

Children's Hospital Los Angeles has received a multi-year $6 million award from the California Institute for Regenerative Medicine (CIRM) to develop innovative stem cell approaches to treat children and adolescents with recurrent solid tumors. The Cancer and Blood Disease Institute (CBDI) is a recognized leader in pediatric cancer care and research.

Cedars-Sinai Cardiac and Thoracic Surgery Experts Available for Interviews During AATS Annual Meeting April 27-30

Cedars-Sinai — Thu, 25 Apr 2024 10:05:04 EST

Surgeons from the Smidt Heart Institute at Cedars-Sinai will be attending the American Association for Thoracic Surgery (AATS) Annual Meeting April 27-30 in Toronto and are available to discuss the latest cardiac surgery news and research.

Fan's Fundraiser Benefits Barbra Streisand Women's Heart Center

Cedars-Sinai — Thu, 25 Apr 2024 00:05:32 EST

Ageless and evergreen: The signature lyric that sums up Robin Lipman's reverence for one of the most iconic entertainers of our time. That epic level of fan appreciation would manifest in a fundraising campaign to benefit the Barbra Streisand Women's Heart Center at the Smidt Heart Institute at Cedars-Sinai.

When Studies Conflict: Building a Decision Support System for Clinicians

Perelman School of Medicine at the University of Pennsylvania — Wed, 24 Apr 2024 11:05:05 EST

When one study says a treatment works, but another says it doesn't (or worse), how are clinicians supposed to determine what they should do? A Penn Medicine team recently received funding from PCORI to build a guide system for these situations

Artificial Intelligence Can Evaluate Cardiovascular Risk During CT Scan

Cedars-Sinai — Tue, 23 Apr 2024 15:05:16 EST

A recent study designed and implemented by investigators at Cedars-Sinai found that artificial intelligence (AI) can accurately evaluate cardiovascular risk during a routine chest computed tomography (CT) scan without contrast.

Simulation reveals new mechanism for membrane fusion

UT Southwestern Medical Center — Mon, 22 Apr 2024 14:05:28 EST

An intricate simulation performed by UT Southwestern Medical Center researchers using one of the world's most powerful supercomputers sheds new light on how proteins called SNAREs cause biological membranes to fuse.

Cell Biology: Molecular Code Stimulates Pioneer Cells to Build Blood Vessels in the Body

Karlsruhe Institute of Technology (KIT) — Wed, 17 Apr 2024 07:05:23 EST

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year. A team of KIT researchers has now identified a new cell type in blood vessels responsible for vascular growth.

Annals supplement highlights important new evidence readers 'may have missed' in 2023

American College of Physicians (ACP) — Mon, 15 Apr 2024 17:00:00 EST

A new supplement published in Annals of Internal Medicine highlights important new evidence published in 2023 that readers may have missed.

Exercise Testing Uncovers Cardiovascular Disease Risk Factor in Black Postmenopausal Women

American Physiological Society (APS) — Mon, 15 Apr 2024 15:05:15 EST

UC Irvine-led research team shows importance of under-recognized genetic factor lipoprotein(a) in predicting heart disease in a large multiethnic US population

University of California, Irvine — Mon, 15 Apr 2024 14:00:00 EST

In what is the largest, most ethnically diverse long-term study of a U.S. population, a University of California, Irvine research team found that an under-recognized genetic cholesterol-like particle called lipoprotein(a) can predict future cardiovascular disease.

Gene Expression in Metabolic Heart Disease Differs between Males and Females

American Physiological Society (APS) — Mon, 15 Apr 2024 13:05:20 EST

Covid Vaccines Not Linked to Fatal Heart Problems in Young People, CDC Finds

George Washington University — Mon, 15 Apr 2024 11:05:30 EST

Hypertensive Disorders of Pregnancy Increase Risk of Cardiovascular Death After Giving Birth

Rutgers University-New Brunswick — Thu, 11 Apr 2024 09:05:34 EST

Rutgers Health researchers identify patients at risk for preventable death in the year after pregnancy.

A Pulse of Innovation: AI at the Service of Heart Research

Columbia University School of Engineering and Applied Science — Wed, 10 Apr 2024 16:05:54 EST

Columbia Engineers unveiled BeatProfiler, a groundbreaking new tool-- a comprehensive software that automates the analysis of heart cell function from video data. It's the first system to integrate the analysis of different heart function indicators into one tool, speeding up the process significantly and reducing the chance for errors.

Cleveland Clinic, Tufts University Research Ties Gut Microbial TMAO Pathway to Chronic Kidney Disease

Cleveland Clinic — Tue, 09 Apr 2024 14:00:00 EST

New findings from Cleveland Clinic and Tufts University researchers show high blood levels of TMAO (trimethylamine N-oxide) predicts future risk of developing chronic kidney disease over time.

New Warnings About Heart Pumps Linked to 49 Deaths

George Washington University — Tue, 09 Apr 2024 12:05:28 EST

Ochsner Health Utilizes Groundbreaking Ablation System for Atrial Fibrillation

Ochsner Health — Tue, 09 Apr 2024 11:05:12 EST

The John Ochsner Heart & Vascular Institute brings an advancement in the treatment of heart rhythm disorders to the New Orleans and Gulf South region utilizing a new cardiac ablation procedure, the FARAPULSE Pulse Field Ablation System.

Cardiology team performs novel heart artery repair with newly approved device

UC Davis Health — Mon, 08 Apr 2024 17:05:36 EST

UC Davis Medical Center has become the first hospital in Western U.S. to perform a successful transcatheter tricuspid valve repair procedure with a groundbreaking catheter.

Salt substitution associated with lower risk for all-cause, cardiovascular mortality

American College of Physicians (ACP) — Mon, 08 Apr 2024 17:00:00 EST

A systematic review of 16 randomized controlled trials found that the use of a salt substitute in food preparation was associated with a lower risk for both all-cause and cardiovascular mortality. The analysis is published in Annals of Internal Medicine.

Mountainside Medical Center Recognized for Excellence with ACC Cardiac Cath Lab Accreditation with PCI

Hackensack Meridian Health (Mountainside Medical Center) — Mon, 08 Apr 2024 16:20:22 EST

The American College of Cardiology has recognized Hackensack Meridian Mountainside Medical Center for its demonstrated expertise and commitment in treating patients who come to a cardiac cath lab for care, including diagnostic catheterizations and percutaneous coronary intervention (PCI) procedures

Hackensack University Medical Center Ranked as NJ's Highest-Volume MitraClip Center

Hackensack Meridian Health — Mon, 08 Apr 2024 10:05:11 EST

Hackensack University Medical Center Structural Heart team is among the highest-volume MitraClip groups in the nation, with success rates and outcomes that exceed national averages.

Researchers Uncover Potential Molecular Mechanism behind Caffeine's Benefit to Sleep Deprivation-induced Cognitive Difficulties

American Physiological Society (APS) — Mon, 15 Apr 2024 14:05:47 EST

UC Irvine researchers find new origin of deep brain waves

University of California, Irvine — Wed, 10 Apr 2024 13:05:05 EST

University of California, Irvine biomedical engineering researchers have uncovered a previously unknown source of two key brain waves crucial for deep sleep: slow waves and sleep spindles.

Embracing the Eclipse: Shedding Light on the Importance of Light for our Sleep and Daily Routines

American Academy of Sleep Medicine (AASM) — Fri, 05 Apr 2024 09:20:55 EST

In light of the solar eclipse, the American Academy of Sleep Medicine reminds Americans of the important role light plays in our day-to-day lives and in regulating our sleep/wake cycle.

Nerve stimulation for sleep apnea is less effective for people with higher BMIs

Washington University in St. Louis — Thu, 04 Apr 2024 11:00:00 EST

A sleep apnea treatment known as hypoglossal nerve stimulation is less effective in people with higher body mass indexes (BMIs), according to a new study by researchers at Washington University School of Medicine in St. Louis.

Insomnia Symptoms May Predict Subsequent Drinking in Adults

Research Society on Alcoholism — Thu, 28 Mar 2024 10:00:00 EST

People with symptoms of insomnia may be likely to increase their drinking over time, according to a study published in Alcohol: Clinical and Experimental Research. In the study of adult drinkers, people who had worse insomnia symptoms at the outset of the study tended to increase the amount they drank and the number of times they binge drank during the subsequent year. The researchers found that, even at subclinical levels, insomnia symptoms were a significant predictor of future drinking in adults, suggesting that insomnia symptoms should be addressed to help reduce the risk of problem drinking.

Jet Lag Is a Drag: Why It Happens and How to Avoid It

Baylor University — Mon, 25 Mar 2024 11:05:33 EST

Anyone who has traveled has probably experienced jet lag - that exhausted feeling that comes after long travel and trips. But why do we feel jet lagged and how can we avoid it?

New Research Continues to Support Massage Therapy for Improving Sleep Quality

American Massage Therapy Association (AMTA) — Tue, 19 Mar 2024 12:25:30 EST

It's National Sleep Awareness Month, and the American Massage Therapy Association (AMTA) is sharing the latest research on how massage can improve sleep quality.

Springing forward to Daylight Saving Time can take a toll on your health.

George Washington University — Tue, 12 Mar 2024 09:05:02 EST

Are You Getting Enough Sleep? Probably Not.

Rutgers University-New Brunswick — Fri, 08 Mar 2024 10:05:00 EST

March 15 marks World Sleep Day, an annual call to action from the World Sleep Society to spread awareness of the need to get sufficient sleep to stay healthy. This year's theme is "Sleep Equity for Global Health."

Mount Sinai Sleep Experts Available for Interview on Daylight Saving Time and World Sleep Day

Mount Sinai Health System — Thu, 07 Mar 2024 09:50:47 EST

Mount Sinai Researchers to Develop and Study AI-Powered Models That Identify Risk for Cardiovascular Disease and Treatment Response in Patients With Obstructive Sleep Apnea

Mount Sinai Health System — Thu, 07 Mar 2024 09:05:29 EST

Team studying predictive models for serious sleep condition awarded $3 million NIH grant

Does Stroke Risk Linked to Sleep Apnea Vary by Race?

American Academy of Neurology (AAN) — Wed, 06 Mar 2024 16:00:00 EST

The risk of stroke tied to sleep apnea may vary for Black people and white people, according to a study published in the March 6, 2024, online issue of Neurology(r), the medical journal of the American Academy of Neurology.

University of Michigan Sleep Experts available for interview on Daylight Saving Time, World Sleep Day and more

Michigan Medicine - University of Michigan — Wed, 06 Mar 2024 15:05:15 EST

Experts from the Michigan Medicine Sleep Disorders Centers are available to talk about Daylight Saving Time and World Sleep Day.

Daylight Saving Time Begins This Weekend, Hackensack Meridian Sleep Experts Available On Health Impact, How To Prepare Your Body For The Loss Of Sleep And Why They Want Us To Stop "Springing Forward" To Daylight Saving Time

Hackensack Meridian Health — Wed, 06 Mar 2024 08:05:54 EST

Sleep Medicine experts on the health impacts of Daylight Saving Time

SLU/YouGov Poll: Majority of Missouri Voters Want to Say Goodbye to Switching Their Clocks

Saint Louis University — Tue, 05 Mar 2024 10:05:33 EST

In February 2024, the SLU/YouGov Poll asked 900 likely Missouri voters their preferences on Daylight Saving Time. The poll found that a vast majority of Missouri voters prefer a consistent time throughout the year.

Effects of "Blue Light" on Human Health Still Unclear

Wolters Kluwer Health: Lippincott — Mon, 04 Mar 2024 15:05:47 EST

The International Commission on Non-Ionizing Radiation Protection (ICNIRP) has identified a lack of consensus among public health officials about whether SWL from artificial sources disrupts circadian rhythm, and if so, whether SWL-disrupted circadian rhythm is associated with adverse health outcomes.

Sleep Apnea Symptoms Linked to Memory and Thinking Problems

American Academy of Neurology (AAN) — Sun, 03 Mar 2024 16:00:00 EST

People who experience sleep apnea may be more likely to also have memory or thinking problems, according to a preliminary study released today, March 3, 2024, that will be presented at the American Academy of Neurology's 76th Annual Meeting taking place April 13-18, 2024, in person in Denver and online. The study shows a positive association but did not determine whether sleep apnea causes cognitive decline.

Healthy sleep needs a healthy day: boost exercise to beat your bedtime blues

University of South Australia — Thu, 29 Feb 2024 22:05:40 EST

A world first study from the University of South Australia shows that getting a good night's sleep is tied to how you structure your day, with exercise at the heart of sleep quality.

Springing Forward: How to Navigate Moving the Clock Ahead

Rutgers University-New Brunswick — Thu, 29 Feb 2024 14:05:00 EST

Rutgers circadian rhythm and sleep experts discuss the impact of the time change on mental and physical health

Study Reveals the Impact of Behavioral Health Disorders on Cancer Surgery Outcomes

American College of Surgeons (ACS) — Thu, 29 Feb 2024 11:00:00 EST

Researchers have discovered new insights into the relationship between cancer surgery outcomes and behavioral health disorders (BHDs), publishing their findings in the Journal of the American College of Surgeons (JACS).

Researchers Discover Genetic Locations for Increased Risk of Hidradenitis Suppurativa

University of North Carolina School of Medicine — Wed, 26 Jul 2023 15:05:10 EST

Hidradenitis suppurativa (HS) is a chronic inflammatory follicular disease which causes painful lumps to form under the skin. The lumps typically form in areas where skin rubs together - such as the armpits, groin, and under the breasts. HS can range in severity from occasional fluid-filled abscesses to widespread rope-like scarring, chronic pain, and increase of infection.

Mount Sinai Awarded Prestigious $1.3 Million Grant to Expand Research Training Program in Skin Biology

Mount Sinai Health System — Mon, 03 Apr 2023 08:50:39 EST

The Kimberly and Eric J. Waldman Department of Dermatology at the Icahn School of Medicine at Mount Sinai will expand its research training program in skin biology with support from a five-year, $1.3 million T32 grant from the National Institutes of Health (NIH) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

An extra X chromosome-linked gene may explain decreased viral infection severity in females

University of California, Los Angeles (UCLA), Health Sciences — Thu, 16 Mar 2023 19:25:22 EST

Researchers may have found why viral infections hit males more severely than females. They found that female mouse and human NK cells have an extra copy of an X chromosome-linked gene called UTX. UTX acts as an epigenetic regulator to boost NK cell anti-viral function, while repressing NK cell numbers.

Researchers uncover new cell types involved in osteoarthritis

Michigan Medicine - University of Michigan — Thu, 09 Mar 2023 14:55:39 EST

A Michigan Medicine study has identified a new potential target for treating osteoarthritis - a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.

New Study: Abatacept Therapy Offers Promising Results Treating Juvenile Dermatomyositis

George Washington University — Wed, 08 Mar 2023 12:40:35 EST

Study Finds Lower Risk of Severe Infection and Hospitalization with Belimumab Compared to Oral Immunosuppressants

American College of Rheumatology (ACR) — Tue, 08 Nov 2022 11:50:52 EST

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, found that the biologic B-cell inhibitor belimumab was associated with a lower risk of severe infections and hospitalizations compared to nonbiologic immunosuppressants.

Holding Mycophenolate Mofetil for 10 Days or More May Improve COVID-19 Vaccine Response

American College of Rheumatology (ACR) — Tue, 08 Nov 2022 11:20:11 EST

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, demonstrated that withholding mycophenolate mofetil for 10 days significantly increased antibody response after 2 doses of COVID-19 vaccine, without a significant increase in flares.

Study Finds AAV Characteristics and Treatments Vary Across Lifespan

American College of Rheumatology (ACR) — Tue, 08 Nov 2022 11:05:20 EST

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, demonstrated an association between age of diagnosis and clinical characteristics and treatments in Anti-neutrophil cytoplasmic antibody-associated vasculitis patients.

Novel Study Identifies Key Molecular Players in Rheumatoid Arthritis

University of California San Diego — Mon, 24 Oct 2022 17:05:12 EST

Using a novel systems biology approach, scientists at UC San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis, a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

Scientists ID pathway that triggers mice to scratch when they see others do the same

Washington University in St. Louis — Tue, 04 Oct 2022 11:00:34 EST

Researchers at Washington University School of Medicine in St. Louis have identified a pathway in the brains of mice that is activated when the animals see other mice scratching, but that pathway does not run through the visual cortex.

New UCI-Led Study Reveals Characteristics of Stable Vitiligo Skin Disease

University of California, Irvine — Mon, 06 Jun 2022 16:05:00 EST

A new study, led by researchers from the University of California, Irvine, reveals the unique cell-to-cell communication networks that can perpetuate inflammation and prevent repigmentation in patients with vitiligo disease.

Neural Pathway Key to Sensation of Pleasant Touch Identified

Washington University in St. Louis — Thu, 28 Apr 2022 14:00:00 EST

Researchers from the Washington University Center for the Study of Itch and Sensory Disorders have identified a specific neuropeptide and a neural circuit that transmit pleasant touch from the skin to the brain. The findings eventually may help scientists better understand and treat disorders characterized by touch avoidance and impaired social development.

Piezo1 Possible Key to Supporting Muscle Regeneration in Duchenne Muscular Dystrophy

Perelman School of Medicine at the University of Pennsylvania — Fri, 18 Mar 2022 14:00:00 EST

Tracing the impact of a single protein, Piezo1, Penn researchers found that restoring it in muscles affected by Duchenne muscular dystrophy could improve their ability to heal efficiently

Origin of Rare Disease FOP Rooted in Muscle Regeneration Dysfunction

Perelman School of Medicine at the University of Pennsylvania — Fri, 14 Jan 2022 05:00:00 EST

A mutation in the gene that causes fibrodysplasia ossificans progressiva (FOP) doesn't just cause extra bone growth but is tied to a problem in generating new muscle tissue after injury

Mount Sinai Awarded Prestigious $4 Million Grant to Launch Skin Biology and Diseases Resource-based Center

Mount Sinai Health System — Wed, 20 Oct 2021 08:00:11 EST

The Icahn School of Medicine at Mount Sinai is establishing a Skin Biology and Diseases Resource-based Center (SBDRC), funded by a $4 million grant from the National Institutes of Health and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).

Drug Cocktail Reduces Aging-Associated Disc Degeneration

Thomas Jefferson University — Fri, 03 Sep 2021 05:00:00 EST

Therapies that target aging cells early pave the way to easing back pain

Rheumatoid arthritis treated with implanted cells that release drug

Washington University in St. Louis — Wed, 01 Sep 2021 14:00:00 EST

Researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, deliver a biologic drug in response to inflammation.

Penn Center for Musculoskeletal Disorders NIH Grant Renewed for $4 Million

Perelman School of Medicine at the University of Pennsylvania — Wed, 25 Aug 2021 10:35:03 EST

The United States' longest-running NIH-sponsored musculoskeletal research center will receive $4M to continue its studies of everything from ligament tears to osteoarthritis

'Fortunate Accident' May Yield Immunity Weapon Against Antibiotic-Resistant Bacteria

Johns Hopkins Medicine — Wed, 07 Jul 2021 14:30:01 EST

In what turned out to be one of the most important accidents of all time, Scottish bacteriologist Alexander Fleming returned to his laboratory after a vacation in 1928 to find a clear zone surrounding a piece of mold that had infiltrated a petri dish full of Staphylococcus aureus (S. aureus), a common skin bacterium he was growing.

What makes us sneeze?

Washington University in St. Louis — Tue, 15 Jun 2021 11:00:00 EST

What exactly triggers a sneeze? A team led by researchers at Washington University School of Medicine in St. Louis has identified, in mice, specific cells and proteins that control the sneeze reflex. Better understanding of what causes us to sneeze -- specifically how neurons behave in response to allergens and viruses -- may point to treatments capable of slowing the spread of infectious respiratory diseases.

Tip Sheet: Weight loss drugs and cancer prevention, Fred Hutch at AACR, lymphedema Q&A -- and new vice president and chief nursing officer

Fred Hutchinson Cancer Center — Wed, 03 Apr 2024 18:05:00 EST

SEATTLE -- April 3, 2024 -- Below are summaries of recent Fred Hutchinson Cancer Center research findings, patient stories and other news. If you're covering the American Association for Cancer Research (AACR) Annual Meeting, please see our list of and contact to set up interviews.

Wilmer Eye Institute Awarded More Than $20 Million for Clinical Trial Investigating Genetic Eye Condition

Johns Hopkins Medicine — Wed, 03 Apr 2024 10:00:08 EST

The Wilmer Eye Institute, Johns Hopkins Medicine has received two awards totaling more than $20 million from the National Eye Institute at the National Institutes of Health, both of which will be used for a six-year clinical trial investigating a potential treatment for the most common inherited retinal disease, retinitis pigmentosa.

Curtis L. Cetrulo, Jr., MD, Selected as Lyon Family Chair in Plastic Surgery

Cedars-Sinai — Wed, 03 Apr 2024 01:05:49 EST

Curtis L. Cetrulo Jr., MD, vice chair of Research in the Department of Surgery and director of the Division of Plastic Surgery, has been selected as the General William and Willa Dean Lyon Family Chair in Reconstructive and Plastic Surgery.

One in five people with cancer participate in medical research studies

Fred Hutchinson Cancer Center — Tue, 02 Apr 2024 16:00:07 EST

Researchers from Fred Hutchinson Cancer Center, the American Cancer Society Cancer Action Network and peer institutions released new findings in the Journal of Clinical Oncology showing that when all types of cancer research studies are considered, at least one in five people with cancer in the U.S., or 21.9%, participate in some form of clinical research.

Breakthrough in Triple Negative Breast Cancer Shows Optimal Timing for Immunotherapy

UT Southwestern Medical Center — Mon, 01 Apr 2024 17:05:00 EST

Yale Cancer Center Experts, Scientists to Share Vision and Research at Leading Conference

Yale Cancer Center/Smilow Cancer Hospital — Mon, 01 Apr 2024 14:05:18 EST

The five-day session (April 5-10), themed as "Inspiring Science. Fueling Progress. Revolutionizing Care," will include new findings from Yale Cancer Center researchers.

UChicago Medicine: NCI renews Cancer Center's premier 'Comprehensive' designation amid 50th anniversary celebration

University of Chicago Medical Center — Mon, 01 Apr 2024 10:05:18 EST

A 'Comprehensive Cancer Center' is the top U.S. designation for cancer research and treatment facilities recognized by high-quality research that leads to major shifts in cancer care.

Study explores the future of at-home cancer treatment

Keck Medicine of USC — Thu, 28 Mar 2024 12:00:49 EST

A clinical trial from Keck Medicine of USC will test the feasibility of treating non-small cell lung cancer with immunotherapy provided at home.

Combining Epigenetic Cancer Medications May Have Benefit for Colorectal Cancers and Other Tumor Types

Van Andel Institute — Wed, 27 Mar 2024 14:00:00 EST

A pair of medications that make malignant cells act as if they have a virus could hold new promise for treating colorectal cancers and other solid tumors, reports a study published today in Science Advances.

Gene Therapy Offers Hope for Giant Axonal Neuropathy Patients

UT Southwestern Medical Center — Wed, 27 Mar 2024 12:05:53 EST

A gene therapy developed by researchers at UT Southwestern Medical Center for a rare disease called giant axonal neuropathy (GAN) was well tolerated in pediatric patients and showed clear benefits, a new study reports. Findings from the phase one clinical trial, published in the New England Journal of Medicine, could offer hope for patients with this rare condition and a host of other neurological diseases.

UCI Health celebrates transformational acquisition of four community hospitals

University of California, Irvine — Wed, 27 Mar 2024 10:05:56 EST

UCI Health, the clinical enterprise of the University of California, Irvine, has completed the acquisition of four hospitals and associated outpatient locations from Tenet Healthcare Corporation.

Empowering Minority Cancer Patients: Tips for Advocacy and Support

Rutgers Cancer Institute of New Jersey — Wed, 27 Mar 2024 09:05:27 EST

Mariam F. Eskander, MD, MPH, surgical oncologist in the Gastrointestinal Oncology Program at Rutgers Institute of New Jersey, offers insight and tips for minority individuals navigating a cancer diagnosis and how we can all work together to mitigate cancer disparities.

10 Facts about Head & Neck Cancers

Rutgers Cancer Institute of New Jersey — Wed, 27 Mar 2024 09:05:06 EST

Head and neck cancer is the term used to describe a number of different malignant tumors that develop in or around the throat, larynx, nose, sinuses and mouth.

Friend or foe: A closer look at the role of health care algorithms in racial and ethnic disparities

Perelman School of Medicine at the University of Pennsylvania — Mon, 25 Mar 2024 12:05:48 EST

For years, it was harder for Black patients to secure a coveted spot on the national kidney transplant waitlist because a clinical algorithm was making Black patients appear healthier than they were.

Inflammation-Reducing Drug Shows No Benefit for Dry Age-Related Macular Degeneration in Nih Trial

NIH, National Eye Institute (NEI) — Thu, 21 Mar 2024 11:30:33 EST

The drug minocycline, an antibiotic that also decreases inflammation, failed to slow vision loss or expansion of geographic atrophy in people with dry age-related macular degeneration (AMD), according to a phase II clinical study at the National Eye Institute (NEI), part of the National Institutes of Health.

Inflammation-reducing drug shows no benefit for dry age-related macular degeneration in NIH trial

NIH, National Eye Institute (NEI) — Thu, 21 Mar 2024 11:05:08 EST

ScienceMedia Welcomes Visionary Leaders to Advisory Board, Paving the Way for a New Era of Innovation

ScienceMedia — Thu, 21 Mar 2024 07:05:48 EST

ScienceMedia, a global SaaS provider redefining the landscape of clinical mastery in the biotech and pharma industries, announces the formation of its inaugural advisory board.

Adding ribociclib to hormone therapy reduces the risk of breast cancer recurrence

University of California, Los Angeles (UCLA), Health Sciences — Wed, 20 Mar 2024 17:05:51 EST

A new treatment approach that combines a targeted therapy drug with hormone therapy significantly increased the amount of time a person with stage 2 or 3 HR-positive, HER2-negative early breast cancer lives without the cancer returning, according to a new study co-led by UCLA Health Jonsson Comprehensive Cancer Center investigators.

ATS 2024 Conference Program is Live! Register Now for Scientific Sessions in Pulmonary, Critical Care and Sleep Medicine

American Thoracic Society (ATS) — Tue, 19 Mar 2024 11:05:39 EST

The ATS 2024 International Conference Program is now live! Get ready for a series of dynamic scientific programming with presentations covering AI in thoracic medicine, the basic sciences, research breakthroughs and clinical treatment, as well as spotlighting the next generation of innovators in pulmonary, critical care and sleep medicine.

Chop Researchers Find Branched Chain Amino Acid Supplementation May Aid in Concussion Recovery

Children's Hospital of Philadelphia — Tue, 19 Mar 2024 10:05:20 EST

In the first clinical trial of a targeted pharmacologic therapeutic for mild traumatic brain injury in pediatric patients, scientists have found preliminary evidence that adolescents and young adults with concussion who take a specific formulation of branched chain amino acid (BCAA) supplements after injury experience faster symptom reduction and return to physical activity.