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Analyse unseres Partner-Portals "Economist" - Europäer befürchten ernste Konsequenzen nach Macrons "Hirntod"-Kritik an Nato

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Die Eile Emmanuel Macrons, eine Stütze für die Nato ins Leben zu rufen, könnte die Risse in Europa verstärken. Mit Projekten wie E2I und der Bereitschaft, vorschnell zu handeln und Dinge zu zerstören, könnte sich Macron Trump zum Feind machen.
          

Gastbeitrag von Gabor Steingart - Während von der Leyen feiert, baut Macron seine geheime Europa-Basis auf

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Ursula von der Leyen glaubt, ihre große Zeit habe begonnen, nachdem das EU-Parlament gestern die Kommission bestätigte. Erleichtert rief die Deutsche den Abgeordneten gestern zu: „Let‘s get to work!“ Ihr Problem: Emmanuel Macron ist schon da.Von Gastautor Gabor Steingart
          

[ASAP] Unraveling the Conformations of Backbone and Side Chains in Thermosensitive Bottlebrush Polymers

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Macromolecules
DOI: 10.1021/acs.macromol.9b01021

          

[ASAP] Scaling and Entanglement Properties of Neutral and Sulfonated Polystyrene

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Macromolecules
DOI: 10.1021/acs.macromol.9b01583

          

[ASAP] Impact of Cyclic Block Copolymer Chain Architecture and Degree of Polymerization on Nanoscale Domain Spacing: A Simulation and Scaling Theory Analysis

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Macromolecules
DOI: 10.1021/acs.macromol.9b02015

          

[ASAP] Living Initiator-Transfer Anionic Polymerization of Isocyanates by Sodium Diphenylamide

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Macromolecules
DOI: 10.1021/acs.macromol.9b01523

          

[ASAP] Shape Memory Behavior of Emulsion-Templated Poly(e-Caprolactone) Synthesized by Organocatalyzed Ring-Opening Polymerization

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Macromolecules
DOI: 10.1021/acs.macromol.9b01780

          

[ASAP] Ternary Memory Devices Based on Bipolar Copolymers with Naphthalene Benzimidazole Acceptors and Fluorene/Carbazole Donors

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Macromolecules
DOI: 10.1021/acs.macromol.9b02033

          

[ASAP] Green-Solvent-Processed Amide-Functionalized Conjugated Polymers Prepared via Direct Arylation Polymerization (DArP)

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Macromolecules
DOI: 10.1021/acs.macromol.9b02014

          

[ASAP] Molecular Dynamics in Polystyrene Single-Chain Nanoparticles

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Macromolecules
DOI: 10.1021/acs.macromol.9b02070

          

[ASAP] Defect Removal by Solvent Vapor Annealing in Thin Films of Lamellar Diblock Copolymers

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Macromolecules
DOI: 10.1021/acs.macromol.9b01181

          

[ASAP] Cell Model Approaches for Predicting the Swelling and Mechanical Properties of Polyelectrolyte Gels

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Macromolecules
DOI: 10.1021/acs.macromol.9b01216

          

[ASAP] Kinetics of Anionic Living Copolymerization of Isoprene and Styrene Using in Situ NIR Spectroscopy: Temperature Effects on Monomer Sequence and Morphology

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Macromolecules
DOI: 10.1021/acs.macromol.9b01790

          

[ASAP] Phase-Locked Dynamic and Mechanoresponsive Bonds Design toward Robust and Mechanoluminescent Self-Healing Polyurethanes: A Microscopic View of Self-Healing Behaviors

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Macromolecules
DOI: 10.1021/acs.macromol.9b02089

          

[ASAP] Synthesis of Long-Chain Branched Polyolefins by Coordinative Chain Transfer Polymerization

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Macromolecules
DOI: 10.1021/acs.macromol.9b01705

          

Macron et son remède social...(le matraquage) ...

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Par: Pieds Noirs 9A.. Macron veut détruire la France . Il prend les Français pour ses domestiques .Le fouet est les taxes pour les matraqués .Comme la honte sur nos vieux sur le  supplément  de "CSG"  ...Si l’immigration ne ruinait pas le pays, tous les Français auraient des retraites...
          

New (and New to Us) Materials in October & November 2019

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Collection development activities have always included a mix of purchases, gifts, and rediscovered items - at least during my twenty-years on the job. Items added to the Research Room during October 2019 continue that long tradition.

A memoir is the least objective, most personal form of writing. There have been a string of memorials and memoirs about Pat Conroy since his 70th birthday and quick death from pancreatic cancer in March 2016. Earlier this year we added memoirs about him by Bernie Schein, Pat Conroy: Our Lifelong Friendship and Michael Mewshaw, The Lost Prince: A Search for Pat Conroy. The latest memoir is perhaps the most personal of all. Tell Me A Story: My Life with Pat Conroy by Cassandra King Conroy, 2019 recounts "King-Ray's" life and times as the girlfriend, wife and widow of the Lowcountry's "Prince of Tides."  
 

Ahora, NationBuilder está en el centro de una investigación que implica a organismos europeos y que, aunque a menor nivel, recuerda demasiado al pasado escándalo de Cambridge Analytica.

La Eurocámara pasa en un año de exigir cuentas a rendirlas

Hace un año, el Parlamento Europeo exigió a Mark Zuckerberg que rindiera cuentas ante la Eurocámara (no quedando muy satisfecho con el resultado) a causa del escándalo de Cambridge Analytica, desatado tras hacerse público que la compañía británica de comunicación electoral y minería de datos había extraído de Facebook los datos personales de millones de usuarios.

El legislativo europeo terminaría incluso instando a Facebook a someterse a una auditoría para asegurar la protección de los datos de sus usuarios. Y poco después, llegaría a adoptar nuevas normas destinadas a sancionar a los grupos políticos europeos que hicieran mal uso de los datos personales durante las entonces inminentes Elecciones Europeas de 2019.

Irónicamente, ahora tendrá que ser el Parlamento quien rinda cuentas ante el SEPD (Supervisor Europeo de Protección de Datos), tras saberse que NationBuilder había procesado datos privados de 329.000 personas cuando trabajaba para el legislativo comunitario durante las últimas elecciones europeas.

El Parlamento firmó un contrato de 135.000 euros con NationBuilder, para iniciar un "proyecto piloto" con el objetivo de que esta compañía le ayudase a diseñar una campaña informativa que incitara a los votantes del continente a movilizarse para votar.

Utilizaron para ello el sitio web thistimeimvoting.eu, que permitió recopilar los datos de usuarios interesados en el proceso electoral. Datos (nombres, direcciones de correo electrónico, idiomas preferidos y lugar de residencia) que terminaron siendo alojados y analizados en los servidores estadounidenses de NationBuilder.

Según los representantes de la institución, durante este proyecto, se habría hecho uso únicamente de los "servicios básicos" de la plataforma estadounidense (como gestor de contenidos y envíos de e-mail) y que en ningún momento hicieron uso de funcionalidades que recurrieran a cruzar o compartir datos con terceros.

Según ha aclarado Wojciech Wiewiórowski, adjunto del Supervisor Europeo, las indagaciones sobre este asunto comenzaron en febrero de 2019, y destaca que en el marco de esta investigación, aún en curso, "existe un buen nivel de cooperación" con el Parlamento Europeo. "El Parlamento de la UE continuará cooperando con el SEPD para aclarar cualquier tema pendiente", aclaran desde el servicio de prensa de la Eurocámara.

Vía | Netzpolitik

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La noticia La Eurocámara deberá rendir cuentas por el uso inadecuado de datos personales durante la última campaña electoral europea fue publicada originalmente en Genbeta por Marcos Merino .


          

Macron Urges End To NATO’s Cold War 2.0 With Russia

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via tomluongo: Last week I went through just some of the highlights as to why Russia is becoming a destination for global capital. For years it’s been a little lonely out here ... Read more
          

Sequences of the 16S and 18S gene and pH determination of the Jena Experiment main plots measured in 2010

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Description

In september 2010 bulk soil samples were taken from 82 plots in the Jena Experiment main experiment. Per plot 5 cores of 15 cm depth were taken, pooled and sieved. From the extracted DNA the 16S and 18S rRNA gene was amplified with primer sets 515f/806r and FR 1/FF390. The samples were subjected to Roche 454 automated sequencer and GS FLX system using titanium chemistry (Macrogen Seoul, Korea). The 16S dataset includes bacterial and archaeal sequences, the 18S dataset includes mainly fungal and protist sequences.
Date made available2017
PublisherPangaea
Geospatial point (coordinates in decimal format)50.946100,11.611300

          

第515回「ここぞという時に体調を崩す、がパターンに。。病気と運命、どう考える?」

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これは簡単で、頭の中にヘンなプログラムが入っているだけです。多くの人が今、「自分の考えや性格」だと思っていることは、実は自分の考えではありません。まだウィルスチェックが働かない子供のうちに脳に入れてしまった単なるプログラムに過ぎず、それは運命でもなければ性格でもなく、一生取れない思考でもないんです。



          

Opponents work for referendum on Macron's plan to privatise Paris Airports

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Opponents of a French government plan to privatise Paris Airports sought to step up public support on Saturday for a petition they hope will trigger a referendum that could block the initiative.
          

Une vision micro et macro pour mener efficacement vos campagnes marketing

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  Le Call Tracking est la seule technologie qui assure le suivi des appels téléphoniques entrants :  statut  de l'appel, durée, géolocalis
          

Macron gratte sous !

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  Dans ses projets, Macron veux récupérer tout l’argent pour pouvoir tous les ans apurer son budget. D’un côté, il y a l’argent du chômage de l’autre celui des caisses de retraite, les deux seraient intégrés au budget de l’état. A partir de là il pourra disposer de deux variables d’ajustement pour combler les déficits […]
          

The Times on Macron’s ‘rapprochement’ with Russia: Old Socialist asks the question, is the New Cold war over?

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This screen shot of a Times report from November 29, 2019  The Times has finally caught up with one of its columnist:   The above from November 13, 2019 that links to this Economist interview of November 7, 2019. On … Continue reading
          

Assemblées générales et délégués élus pour la grève jusqu’au retrait !

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Plus personne ne parvient à tenir la liste des communiqués et des déclarations qui appellent « à un premier jour de grève le 5 décembre  », à une « grève reconductible », à une « grève illimitée », à une « grève jusqu’au retrait de la réforme Macron-Delevoye » … Lire la suite
          

Surprisingly Elegant Parasol Mushroom and Red Cage Fungus Costumes Created for Artist’s Mushroom Thesis

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Artist and student Jamie Green created a pair of surprisingly elegant fungi costumes. The first costume is that of a Macrolepiota Procera or parasol mushroom worn by artist Alyssa Russell, which he plans to use as one “small section” of his “very large mushroom thesis”. This series will be featured in my thesis “More Than...

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The post Surprisingly Elegant Parasol Mushroom and Red Cage Fungus Costumes Created for Artist’s Mushroom Thesis first appeared on Laughing Squid.


          

백트, 비트코인 선물 거래량 계속 경신…COO "BTC 성공하려면 실질적인 유용성 필요"

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세계 최대 거래소 그룹 인터컨티넨탈익스체인지(ICE) 산하 비트코인(Bitcoin, BTC) 선물 거래소 백트(Bakkt)의 수석운영책임(COO) 아담 화이트는 비트코인이 성공하려면 실제적인 유용성이 필요하다고 발언했다.

 

아담 화이트 수석은 26일(현지시간) EJ인사이트와의 인터뷰에서 백트가 시장 투기를 일으키지 않는 상품 구축을 위해 노력하고 있으며, 특히 ‘가격발견(price discovery)’과 리스크 헤징 관리에 있어 백트의 선물 계약이 긍정적으로 역할하고 있다고 강조했다.

 

또 이 같은 시장활용 사례 증가에도 비트코인이 '유용성(utility)'을 갖춰야 한다고 주장했다.

 

그는 "비트코인과 같은 디지털 자산이 실제적인 문제를 해결하는 데 사용돼야 한다. 이를 도입(adoption), 유용성(utility)라고 한다"며 "비트코인의 도입과 유용성을 강화하기 위해 별도의 부서를 두고 새로운 상품과 서비스를 개발하고 있다"고 설명했다.

 

수석은 스테이블 코인에 대해 아직 중립적인 입장이라 밝혔다. 그러면서도 "법정화폐를 담보하는 디지털 자산은 흥미로운 분야"라면서 "향후 위상이 더 높아지면 백트 커스터디 솔루션이 지원할 가능성도 고려한다"고 덧붙였다.

 

페이스북이 추진 중인 스테이블 코인 '리브라' 프로젝트에 대해서는 "규제 반발은 당연하다. 리브라는 전례 없이 경계를 확대해가고 있다"고 평가했다.

 

그는 "이러한 프로젝트가 생겨나고 추진되는 흐름 자체가 중요하다"면서 "문제가 있겠지만 현금 등 다른 것들은 할 수 없는 스테이블 코인만이 할 수 있는 부분이 있을 것"이라 전했다.

 

백트(Bakkt)는 암호화폐 선물 거래소로써 새로운 기관투자자를 유입시킬 것이란 큰 기대를 모았다. 지난 9월에는 실물 인도 비트코인 선물 상품을 출시했으며, 올해 안에 현물 인도 상품을 출시할 계획이다. 그 외 비트코인 옵션 상품도 준비 중이다.

 

비록 출발은 저조했지만 지난 몇 주 간 거래량과 미결제약정이 급증하며 각종 기록들을 연달아 경신하고 있다. 실제로 암호화폐 전문 분석업체 스큐(Skew)에 따르면 백트의 비트코인 선물 미결제약정(open interest) 규모는 100만 달러를 돌파했으며 거래량도 꾸준히 증가 중이다.

 

한편 백트 거래량 봇 트위터 계정 백트봇(@BakktBot)에 따르면, 미국 현지시간 기준 27일 백트 비트코인 선물 거래량이 5,6713 BTC로 역대 최고치를 경신했다. 

 

▲ 출처: 백트봇 트위터     © 코인리더스


이와 관련해 유명 암호화폐 전문 애널리스트 알렉스 크루거(Alex Krüger)는 트위터를 통해 "백트 비트코인 선물의 거래량이 대폭 증가하고 있다. 그러나 중점을 두어야할 점은 거래량이 아닌 실물인수도 규모다. 11월 BTC 선물 실물인수도 규모는 11 BTC, 10월은 15 BTC를 기록했다"고 말했다.

 

 

 


          

Do We Live in a Quantum World?

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At some point, the rules of the subatomic give way to the rules of the macroscopic. But how? We're not exactly sure, and it's been a long, strange journey in trying to answer that question.
          

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  Immerhin, nach einer Dreiviertelstunde kommt dann doch eine Frage, die Ursula von der Leyen überrascht. Die neue Kommissionschefin hat bereits über Klimapolitik geredet und die schwierige Migrationsfrage. Es ging um männliche Egos wie Donald Trump und Emmanuel Macron und die Frage, wie sich ihr Verhältnis zu Angela Merkel mit ihrem neuen Job verändere. Die […]

The post Schlaflos in Brüssel appeared first on Bayern Postille.


          

Daniele Franzella, An Inventory Of | Rizzuto Gallery, Palermo

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Testo di Marta Acciaro — Leggiamo sulla Treccani: “inventàrio s. m. [dal lat. tardo inventarium (der. di inventus, part. pass. di invenire «trovare»), propr. «elenco, registro per trovare ciò che è in un dato luogo»]. – 1. Rilevazione, enumerazione e descrizione, capo per capo, di oggetti, documenti e beni esistenti in un momento determinato in un dato luogo”. Rocco Ronchi nel Novembre 2019 ha tenuto un seminario al Macro di […]
          

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The ultimate PvP guide for Hunter. Find out the best specs, optimal rotations, macros and gear you need to become the best Hunter in Classic WoW
          

Mage PvP Guide - Specs, Duel, BG, Gear

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Cortex-M7 Processor Technical Reference Manual

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ARM® Cortex®-M7 Processor
Technical Reference Manual Revision r0p2



About this book ........................................................................................................... vi
Feedback ..................................................................................................................... x

Chapter 1 Introduction
1.1 About the Cortex-M7 processor ............................................................................... 1-2
1.2 Component blocks ................................................................................................... 1-6
1.3 Interfaces ............................................................................................................... 1-10
1.4 Supported standards ............................................................................................. 1-12
1.5 Design process ...................................................................................................... 1-13
1.6 Documentation ....................................................................................................... 1-14
1.7 Product revisions ................................................................................................... 1-15

Chapter 2 Programmers Model
2.1 About the programmers model ................................................................................ 2-2
2.2 Modes of operation and execution ........................................................................... 2-3
2.3 Instruction set summary ........................................................................................... 2-4
2.4 System address map ............................................................................................... 2-5
2.5 Exclusive monitor ..................................................................................................... 2-7
2.6 Processor core registers .......................................................................................... 2-8
2.7 Exceptions ............................................................................................................... 2-9

Chapter 3 System Control
3.1 About system control ............................................................................................... 3-2
3.2 Register summary .................................................................................................... 3-3
3.3 Register descriptions ............................................................................................... 3-6

Chapter 4 Initialization
4.1 About Initialization .................................................................................................... 4-2

Chapter 5 Memory System
5.1 About the memory system ....................................................................................... 5-2
5.2 Fault handling .......................................................................................................... 5-3
5.3 Memory types and memory system behavior .......................................................... 5-5
5.4 AXIM interface ......................................................................................................... 5-6
5.5 AHB peripheral interface ........................................................................................ 5-22
5.6 AHB slave interface ............................................................................................... 5-30
5.7 TCM interfaces ...................................................................................................... 5-33
5.8 L1 caches .............................................................................................................. 5-35

Chapter 6 Memory Protection Unit
6.1 About the MPU ........................................................................................................ 6-2
6.2 MPU functional description ...................................................................................... 6-3
6.3 MPU programmers model ........................................................................................ 6-4

Chapter 7 Nested Vectored Interrupt Controller
7.1 About the NVIC ........................................................................................................ 7-2
7.2 NVIC functional description ..................................................................................... 7-3
7.3 NVIC programmers model ....................................................................................... 7-4

Chapter 8 Floating Point Unit
8.1 About the FPU ......................................................................................................... 8-2
8.2 FPU functional description ....................................................................................... 8-3
8.3 FPU programmers model ........................................................................................ 8-5

Chapter 9 Debug
9.1 About debug ............................................................................................................ 9-2
9.2 About the AHBD interface ........................................................................................ 9-7
9.3 About the FPB ......................................................................................................... 9-8

Chapter 10 Cross Trigger Interface
10.1 About the CTI ......................................................................................................... 10-2
10.2 Cortex-M7 CTI functional description .................................................................... 10-3
10.3 CTI programmers model ........................................................................................ 10-5

Chapter 11 Data Watchpoint and Trace Unit
11.1 About the DWT ...................................................................................................... 11-2
11.2 DWT functional description .................................................................................... 11-3
11.3 DWT programmers model ..................................................................................... 11-4

Chapter 12 Instrumentation Trace Macrocell Unit
12.1 About the ITM ........................................................................................................ 12-2
12.2 ITM functional description ...................................................................................... 12-3
12.3 ITM programmers model ....................................................................................... 12-4

Chapter 13 Fault detection and handling
13.1 About fault detection and handling ........................................................................ 13-2
13.2 Cache RAM protection ........................................................................................... 13-3
13.3 Logic protection ..................................................................................................... 13-6

Appendix A Revisions
          

Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.

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Biomarkers Apo10 and TKTL1: Epitope-detection in monocytes (EDIM) as a new diagnostic approach for cholangiocellular, pancreatic and colorectal carcinoma.

Cancer Biomark. 2019 Nov 15;:

Authors: Saman S, Stagno MJ, Warmann SW, Malek NP, Plentz RR, Schmid E

Abstract
OBJECTIVE: The EDIM (Epitope detection in monocytes) blood test is based on two biomarkers Apo10 and TKTL1. Apo10 is responsible for cell proliferation and resistance to apoptosis. TKTL1 plays a major role in anaerobic glycolysis of tumor cells, leading to destruction of the basal membrane and metastasis as well as in controlling cell cycle. For the first time we analyzed Apo10 and TKLT1 in patients with cholangiocellular (CCC), pancreatic (PC), and colorectal carcinoma (CRC).
METHODS: Blood samples of 62 patients with CCC, PC, and CRC were measured and compared to 29 control patients. We also investigated 13 patients with inflammatory conditions, because elevated TKTL1 and Apo10 have been previously described in affected individuals. Flow cytometry was used to detect surface antigens CD14+/CD16+ (activated monocytes/macrophages). Percentages of macrophages harboring TKTL1 and Apo10 were determined. A combined EDIM score (EDIM-CS: TKTL1 plus Apo10) was calculated. Results were correlated with serum tumor markers CEA and CA19-9.
RESULTS: Patients with CCC had 100% positive EDIM-CS but CEA and CA19-9 were positive in only 22.2% and 70%, respectively. Patients with PC had 100% positive EDIM-CS but positive tumor markers in only 37.5% (CEA) and 72.7% (CA19-9). Patients with CRC had 100% positive EDIM-CS but only 50% positive CEA. EDIM-CS was positive in 100% (62/62) of all cancer patients and in 0% of healthy individuals. Of the individuals with inflammation, 7.7% had a positive EDIM-CS.
CONCLUSION: The sensitivity of the EDIM blood test and the comparison with traditional tumor markers indicate that this new test might improve the detection of carcinomas (CCC, PC and, CRC) and might be relevant for the diagnosis of all tumor entities.

PMID: 31771043 [PubMed - as supplied by publisher]


          

Azithromycin Affords Neuroprotection in Rat Undergone Transient Focal Cerebral Ischemia

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Repurposing existing drugs represents a promising approach for successful development of acute stroke therapies. In this context, the macrolide antibiotic azithromycin has been shown to exert neuroprotection in mice due to its immunomodulatory properties. Here, we have demonstrated that acute administration of a single dose of azithromycin upon reperfusion produces a dose-dependent (ED50 = 1.40 mg/kg; 95% CI = 0.48–4.03) reduction of ischemic brain damage measured 22 h after transient (2 h) middle cerebral artery occlusion (MCAo) in adult male rats. Neuroprotection by azithromycin (150 mg/kg, i.p., upon reperfusion) was associated with a significant elevation of signal transducer and activator of transcription 3 (STAT3) phosphorylation in astrocytes and neurons of the peri-ischemic motor cortex as detected after 2 and 22 h of reperfusion. By contrast, in the core region of the striatum, drug administration resulted in a dramatic elevation of STAT3 phosphorylation only after 22 h of reperfusion, being the signal mainly ascribed to infiltrating leukocytes displaying an M2 phenotype. These early molecular events were associated with a long-lasting neuroprotection, since a single dose of azithromycin reduced brain infarct damage and neurological deficit measured up to 7 days of reperfusion. These data, together with the evidence that azithromycin was effective in a clinically relevant time-window (i.e., when administered after 4.5 h of MCAo), provide robust preclinical evidence to support the importance of developing azithromycin as an effective acute therapy for ischemic stroke.


          

Investment Expert - Global Equities | Brodard Executive Search

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Zurich, Switzerland, Your Responsibilities   Generate the research content on Global Equities for the advisory group  Deliver actionable thematic/macro trade ideas to the Private Bank Develop researc
          

MRQ: Global Macro Methodology (Analyst) | Credit Suisse

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Mumbai, India, We Offer The Risk Division is a highly visible, dynamic area of the firm where you can be an integral part of the decision-making that supports the bank's business. Our responsibilities range from
          

Le prochain livre de Lionel Jospin, une charge contre Macron ?

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Le prochain livre de Lionel Jospin, une charge contre Macron ? 6medias2 dim 01/12/2019 - 20:43
          

La macrorredada de los Mossos, en imágenes

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Más de 700 agentes de los Mossos d'Esquadra realizan desde poco antes de las seis de la mañana de este viernes una macrorredada en varios puntos de Catalunya contra una organización dedicada al tráfico de armas, drogas y blanqueo de capitales. Se prevén numerosas detenciones. 

Seguir leyendo....


          

Golpe a un clan de narcos de Badalona que se blanqueaba comprando casas

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Una macrorredada de los Mossos dEsquadra en Badalona, y en otros ocho municipios de la corona metropolitana, ha desarticulado este viernes una de las redes de tráfico de droga y de armas más importante de Catalunya. El clan familiar al frente de este entramado residía en Sant Roc, Badalona. Ocho de los dieciséis domicilios registrados en este barrio estaban en el mismo bloque, convertido en el tronco principal de la estructura. Pisos con las puertas blindadas que escondían en su interior droga, armas y una cantidad ingente de dinero en efectivo. En algún piso ha aparecido un armario lleno de fajos de billetes. 

Seguir leyendo....


          

03/12 9am-11am: New Approaches for Modelling Expectations in Economics Conference

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When: -

Where: Bank of England, London

This two-day conference brings together researchers from Europe and North America to discuss ways of moving beyond the assumption of “rational expectations”, a central part of macroeconomic modelling for the past forty years.

The conference is sponsored by the University of Warwick, the Bank of England and the ESRC funded network “Rebuilding Macroeconomics”. This year, the two keynote speakers are Sydney Ludvigson from New York University and Laura Veldkamp of Columbia Business School.

A copy of the conference programme is available to view here.

Registration

This conference is open to faculty members from the University of Warwick and MRes students from the Department of Economics who are pursuing topics in macroeconomics.

Registration is required for this conference. Those wishing to attend should send a request to Michelle Scott of the Bank of England (Michelle.Scott@bankofengland.co.uk ) in advance. Places are limited so early booking is recommended.


          

03/12 1pm-2pm: MTWP (Micro Theory Work in Progress) Workshop - Udara Peiris (Moscow)

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When: -

Where: S2.79

Title: Capital Flow Freezes (joint with Anna Sokolova and Dimitrios P. Tsomocos)

Abstract: The post-2008 period focused attention on “twin-crises”. Banking crises may lead to sovereign crises where fiscal vulnerabilities are exacerbated by the extension of support for the banking system. We develop a model where capital inflow is generated by the private sector to finance investment and consumption expenditure. In the event of an economic contraction, the haircut on outstanding debt is negotiated, or bargained, centrally by the sovereign. The volume of debt and haircut rates are inefficient; in anticipation of high rates of default, the interest rates required by the lender may be prohibitively high for borrowers to accept and capital flows may cease as a unique equilibrium outcome. The inability to roll over debt may mean markets may freeze several periods in advance of significantly large downturns in income. Macroprudential policy targeting capital accumulation may prevent such capital flow freezes and implement constrained efficient outcomes.


          

13/02 2pm-3:30pm: Macro/International Seminar - Cynthia Mei Balloch (LSE)

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When: -

Where: S2.79

Title to be advised.

Seminar organisers: Federico Rossi & Marta Santamaria


          

20/02 2pm-3:30pm: Macro/International Seminar - Michael Waugh (NYU Stern)

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When: -

Where: S2.79

Organisers: Federico Rossi, Christine Braun & Marta Santamaria


          

Quantitative Developer (Front Office), VP | Barclays

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London, United Kingdom, Overall purpose of role Develop the desk delivery tools and analytics used by Macro trading desks to perform custom analysis. Drive the design and implementation of the new Omega analytics library
          

Market Risk Macro Desk VP | Azon Capital Markets

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London, United Kingdom, Key Accountabilities Execute strong risk management for market risks: challenging the business as appropriate, whilst facilitating the business to grow in a scalable and controlled manner. Create
          

#32610: Add macro spacing checks to "make check-spaces"

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Let's check macro spacing like we check other keyword spacing.

And let's check for else {.


          

5G : il faut « prendre au sérieux » les risques technologiques, dit Macron

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La 5G va progressivement débarquer en Europe en 2020. La France fait partie des pays qui seront servis, mais il faudra attendre le mois de juin au minimum à cause d’un retard. Une question existe sur la 5G : faut-il avoir des craintes ? Emmanuel Macron et Jens …

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Bonjour Zalandeau. Désolé, je ne te..critique sur Mes pantoufles s’en vont..Rondinaud..s’est fini !..

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Bonjour Zalandeau.
Désolé, je ne te..critique pas, et je ne t'ai jamais, non plus..critiqué, loin de là.. J'ai mis cela pour ta phrase.. Nous descendrons tant que tous les pays de la planète ne seront pas à un niveau supérieur au nôtre... A ce moment là nous les suivrons dans leur ascension... C'est à dire que nous allons repartir de très bas... Fini les conquêtes sociales, fini les 40 heures. On sait très bien que nos dirigeants, tous partis confondus, et ce, comme je l'ai déjà dit et mis, depuis le premier mandat de Mr. François Mitterrand jusqu'à ce Macron, ont tout cassé !.. Je sais également que ce sont eux qui ont fait la part belle au patronat, comme aux grands groupes, grandes entreprises et grands dirigeants. La marge du patronat, comme des grandes entreprises est toujours énorme, et pas besoin de se tourner vers les plus grands du "CAC 40" pour savoir cela, et avec leurs salaires astronomiques, plus le reste.. Tu as raison pour.. Il faut dire aussi que notre patronat est très resté "19ème siècle"... Ce qui ne nous aide pas... Car, surtout avec cette "fausse" mondialisation..voulue, ce qui "marchait" (façon de parler..) avant, ne marche plus de nos jours.. Ce n'est pas que, comme cette entreprise citée "Rondinaud" et seulement pour ces chaussons et/ou pantoufles, loin de là, il y a tout le reste.. Tant que l'on fera tout..faire et réaliser en Chine, et donc..importer de..Chine, on cassera tout, l'économie, avec cette balance inégale entre, d'un côté, les trop grandes importations, et de l'autre..le peu de produits exportés !!! Notre déficit en balance commerciale extérieur est..énorme ! Le plus grand exemple (pas le seul..hélas..) est bien, et peu avant Noël, ce marché, et cette bataille pour la vente de jouets pour Noël, et que ce soit avec "Joué-Club" comme tant d'autres..On veut toujours faire des marges, et toujours aussi, tirer les prix vers le bas, dans ce sens, et donc, au bout du compte..tromper le client, et les acheteurs potentiels, quand à la valeur réel du produit et surtout..prix !!! Il est vrai, également, et tu as raison, et je te rejoint pour cela, en parlant des..frontières, et de..nos frontières..avant on éait protégé, comme les produits au regard de la concurrence, mais à présent, c'est le "Bronx" total, dans ce sens.. C'est l'Europe de Bruxelles qui a voulu cela, pour ce qui est d'abattre les frontières et "nos" frontières, dans le cadre du libre échange,et donc, de la suppression des taxes douanières, tout circule, dans tous les sens, sans contrôle, ni taxes..rien.. Et dans ce cadre, il y a, ne l'oublions pas..la drogue, l'armement,etc.. Il y a, également et..surtout le trafic financier et le flux de ce trafic financier, sans aucun contrôle ni..taxes ou..impositions !!! Pour ce qui est de.. Quant à la parité Franc-Mark, elle a été respectée lors du passage à l'euro... Sauf que nous, cons comme des Français que nous sommes, avons continué l'inflation des coûts et des dépenses somptuaires contrairement aux Boches qui ont été des gestionnaires rigoureux... Pour ce qui est de la..parité Franc-Mark, on ne pouvait pas faire mieux, car notre économie, à ce moment là, et au moment du passage à l'Euro, allait déjà mal, donc, on avait pas de chance !.. Ce sont eux, oui, je dis bien eux..Les Boches, comme tu dis, qui ont eu la part belle et se sont fait une forme de plus-value là-dessus, et pas nous. Car, le Mark et leur Mark était déjà et toujours plus fort, sans oublier la situation économique de l'Allemagne qui était bien plus stable et équilibrée. Il faut savoir qu'au passage à l'Euro, chaque pays membre a eu l'Euro de la valeur de "sa" monnaie d'avant. Ce qui veut dire que..1 Franc c'était 1 Franc, mais le Mark, avec sa valeur, en change, de..3,45 Francs, ce n'est pas pareil. Que dire des anciens pays de l'Est, avec leur monnaie considérablement dévaluée ?..Ils n'étaient jamais "concernés" par cette fameuse ligne rouge à ne pas dépasser, avec ce taux d'endettement imposé à..3% !!! Les allemands et le gouvernement de Bonn, d'alors, ont réussi à faire une entente avec l'Europe de Bruxelles pour cela, et pour eux seuls.. Voilà pourquoi, Nicolas Sarkozy (qui avait été à Bercy avant..) faisait tout pour éviter que la France ne paie plus ou trop vis-à-vis de l'Europe et pour l'Europe, par rapport à l'Allemagne. Il avait toujours essayé et réussi à "jongler" Merkel et essayer de faire payer d'avantage l'Allemagne par rapport à la France, sauf que après, ça ne marchait plus, voilà tout. D'ailleurs Mr. Schaüble, ministre des finances n'était pas du tout d'accord avec ça, ni jamais d'accord là-dessus, et le faisait savoir, haut et fort à Angela Merkel.. Après, il faut savoir, également que Mme. Merkel a réussi, dès le départ, à faire acheter les formes de dettes, en taux d'intérêts, et concernant les taux d'intérêts de l'Allemagne, par l'Europe, ce qui a, de suite, donné un ballon d'oxygène à l'Allemagne et permis à ce que l'économie allemande passe au-dessus de nous. Et on en est..toujours là !!!.. Voilà pour mes dires et ce que je souhaitais rajouter à cela, mais aucune connotation en conflit quelconque entre nous..rien, je te rassure.. Bonne journée à toi, à plus..Denis.
          

Bonsoir Zalandeau. Tu sais, lorsque nous étions à sur Mes pantoufles s’en vont..Rondinaud..s’est fini !..

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Bonsoir Zalandeau.
Tu sais, lorsque nous étions à Berlin, avec mon épouse et nos trois enfants, alors, bien-sûr, à..Berlin ouest, j'étais toujours surpris par les conditions de vie et de travail, côté Berlin est.. De plus, il y avait cette..monnaie, je veux dire..leur monnaie Deutsch-Mark, mais de l'est(Ost-Mark..), côté est, qui me surprenait toujours.. Je disais alors à mon épouse:" on dirait que ces pièces ont été fabriquées à l'emporte-pièces, dans des feuilles de zinc, comme pour les gouttières, mais pas aussi épais, presque un peu, en exagérant, comme des feuilles de cigarettes.. Cela ne me faisait pas rire, comme cela ne me faisait jamais rire, pour leurs conditions de vie et de travail..encore moins. Pour en venir à ceci.. Lorsque nous étions rentrés en France, après, et un peu avant la chute du mur, je disais ceci à mon épouse: "j'espère et j'ose espérer qu'un jour la France ne sera pas comme l'Allemagne de l'Est, en parlant de ça et de cette monnaie..". A l'époque, au change, pour 100 Marks ouest, j'avais, au bas mot..700 Marks ouest, parfois même..750.. on pourra comprendre aisément pour ce que je dis, même si, à cette époque, le "vrai" Deutsch-Mark" de l'Allemagne de l'ouest et R.F.A., il est vrai, valait, au change.. 3,45 francs !.. Jusqu'où peut et sinon..va..descendre la France ? comme tu dis..nul ne le sait.. Par contre, je sens une pente "vertigineuse", dans le sens du..négatif, et à..tout point, et en..tout point.. (cela aussi, ne me fais pas rire..mais pas rire du tout !..) Je ne suis pas d'accord pour ce que tu mets, je cite.. Nous descendrons tant que tous les pays de la planète ne seront pas à un niveau supérieur au nôtre... A ce moment là nous les suivrons dans leur ascension... Par contre, ce qui est vrai, comme pour mon article, c'est que..tout va mal..de plus en plus..mal (sans être..pessimiste, et..je ne le suis pas,mais bon..). Il est à noter que depuis que nous sommes entré dans l'Europe,mais surtout..avec cette "zone" Euro, et donc, après la mise en place de cette "maudite" monnaie, qui n'en est pas une..de plus.;tout a changé, et pas qu'en bien !!! Nous avons été emporté dans un sillage indescriptible et vent de folie, en nous faisant croire et surtout..promettre..Monts et merveilles ! Pour preuve: une baguette, avant..1 Franc,puis, avec cet Euro, et l'Euro..tout court..1 Euro !!! Ce n'est pas pareil, tout de m^me, non ? La baguette d'alors et qui était encore, à la fin, à 1 Franc, passait à 1 Euro, c'est-à-dire..6,55957 Francs d'avant, pour la comparaison, mais bien comparaison réelle, non ?.. Depuis le gouvernement de Sarkozy, je veux dire Fillon, pour ce qui est de son premier ministre d'alors, ce sont bien eux qui ont commencé à tout démonter, sur le plan social, du travail, comme des salaires.. La pilule amère des heures supplémentaires..c'était également eux, avec d'abord les heures "sup" imposables et imposées, puis, peu de temps après, et sur une courte période, les heures "sup"..défiscalisées (pour les patrons..) et non imposables et non imposées pour nous..puis après, de nouveau plus !!!.. La suppression de postes en fonctionnaires, plus de 1500, c'était également eux, avec Fillon, dont pour les policiers (on a vu après ce que cela a donné au moment de ces attentats..). C'est d'ailleurs, sous..Sarkozy, et avec Mr. Fillon à la manoeuvre (aidé en cela par Mr. Eric Woerth, alors à Bercy..)qu'ils avaient commencé à engager le premier "jet" pour la réforme des retraites et sur les retraites..ne l'oublions pas ! Ensuite, c'est sous Hollande que Macron a changé le contenu du "Code du Travail", avec cette fausse Loi dite et appelé El Khomri, en se servant d'elle comme épouvantail à moineaux face à la presse et la vindicte du peuple, puis, en prolongement..Les..Prudhommes !!! Ce qui me "bouffe", de l'intérieur, et ce, depuis..39 ans, c'est..tout cela !!! On est en train de tout "bousiller", tout..foutre parterre, sur le plan du "Code du Travail", des recours en "Prudhomme", des heures de travail, heures normales (soit-disant..35 heures par semaine..7X5..) et augmentées en souhait des patrons comme bon leur semble et en accord avec le gouvernement et les syndicats, et aussi heures supplémentaires, à la demande, et pas seulement au regard du carnet de commandes, ou de périodes tampons..Il y a également les..congés payés..toujours plus..rognés, comme les jours fériés et autre... Mais, on a surtout..désindustrialisé la France depuis plus de 35 ans, et surtout ces..20 et 10 dernières années..A part l'Airbus, et dans une moindre mesure le T.G.V. (qui ne s'exporte toujours pas bien..), que nous reste-il ? et sans parler de l'industrie automobile qui va mal aussi.. On a "bradé" et vendu l'agriculture Française à l'Europe, grâce à Jacques Delors (père de Martine Aubry, maire de Lille..), et après le fameux remembrement voulu par un certain Edgar Pisani et sous Giscard d'Estaing, sans oublier que tout cela, pour l'agriculture, avait commencé bien avant, et au sortir de la seconde guerre mondiale et avec le fameux "Plan Marshall" qu'on se le dise !!! Bon, je m'arrête là, tellement je suis..dégoûté et..écoeuré à la fois... Bonne soirée tout de même, (on va pas se tirer une balle assis dans le coin d'un mur tout de même..), restons calme et surtout "zen", à plus..Denis. P.S.: nos enfants (ceux déjà grands..), comme ceux de tous,ils ont déjà connu le moins bon, et connaîtront le moins bon, quand à nos petits-enfants et ceux de tous, ils connaîtront le pire !
          

CHP Grup Başkanvekili Özgür Özel: "Macron'un ifadeleri hadsizliktir"

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CHP Grup Başkanvekili Özgür Özel, Fransa Cumhurbaşkanı Emmanuel Macron'un Türkiye'nin NATO müttefiklerinden dayanışma beklememesi gerektiğine yönelik sözlerine ilişkin, "Macron’un ifadeleri bir bütün olarak değerlendirilirse hadsizliktir." dedi.


          

JOHN CHUCKMAN COMMENT: TWO KEY NATO MEMBERS CALLING NAMES IN PUBLIC? – FRANCE AND TURKEY – I TAKE IT AS A SIGN OF AMERICA’S DECLINE IN PRESTIGE AND INFLUENCE – A FEW THOUGHTS ABOUT MACRON AND ERDOGAN

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John Chuckman COMMENT POSTED TO AN ARTICLE IN RUSSIA TODAY   “Macron should have his own ‘brain death’ checked before attacking NATO allies, Erdogan says”   It is a bizarre show, two key members of NATO speaking the way they have. I think the fact that it can happen, and openly, provides a further sign […]
          

'Article 5, Not F-35': French Minister Lashes Out at US for Forcing NATO Members to Buy Its Weapon

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Earlier, French President Emmanuel Macron criticised the current state of the alliance, calling it "brain dead" and sparking heated discussions over his comments. Not all of France's NATO allies agreed with its president's account of the state of the military bloc.
          

Macron et les Maires de France : Jean-Frédéric Poisson sur LCI le 20/11

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Les souvenirs d'un Choc qui avait la Baraka

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Il faisait partie des vétérans invités par Emmanuel Macron au dernier 15 août, à la nécropole de
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Resumen del libro «Macroeconomía» de Paul Samuelson y William Nordhaus

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Por: Leticia Luna Vera Durante más de medio siglo, esta obra ha servido como estándar para la enseñanza de economía elemental en las aulas de todo el mundo. Cada nueva edición ha presentado las mejores aportaciones de los economistas acerca de la manera cómo funcionan los mercados y lo que la sociedad puede hacer para […]

La entrada Resumen del libro «Macroeconomía» de Paul Samuelson y William Nordhaus se publicó primero en Emprendices.


          

3 Key Metrics Suggest Bitcoin Price Has Completed Its Macro Bear Cycle

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Key trading indicators suggest that Bitcoin has completed its macro bear cycle and is ready to rocket to $9,000 this week. Whilst the Bitcoin price (BTC) action may seem be

[[ This is a content summary only. Visit my website for full links, other content, and more! ]]
          

[PAID OTHER] Lost Ark Online Bot,Macro or Script

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Im looking lost ark macro script or bot if u selling pm me please or write discord id ill add.(No need fishing bot)
          

EU | Warum nur?

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Die neue Kommissionspräsidentin von der Leyen will das Nachzügler-Dasein der EU beenden, wenn es ums geopolitische Ranking geht, und eine „Sprache der Macht“ pflegen
Warum nur?

Ursula von der Leyen, ab 1. Dezember im Amt, will in Brüssel eine „wahrhaft geopolitische Kommission“ führen, war zuletzt mehrfach zu hören. Europa müsse „die Sprache der Macht“ lernen. Was in der Konsequenz nur heißen kann: Wird die beherrscht, ist davon Gebrauch zu machen. Zu welchem Zweck und wo überall? Und nicht zuletzt – wie? Durch die extensive Machtprojektion einer EU-Militärunion und unter der Voraussetzung, dass geopolitisches Großmachtdenken nun auch für die EU mehr denn je gilt? Ein wenig inspirierter – um nicht zu sagen: restaurativer Ansatz –, der auf Muster zurückgreift, von denen sich die USA im Nahen Osten gerade befreien. Sollte von der Leyen diesen Ansatz verfolgen, wäre weiter zu fragen: Kennt die neue Kommissionspräsidentin den Zustand der EU? Ist der geeignet, sie als Global Player über ihre Wirtschafts- und Handelsmacht hinaus in Szene zu setzen?

Dritter Weg, dritte Kraft?

Seit geraumer Zeit bereits ist der 27-Staaten-Bund alles andere als ein monolithischer Machtblock, mit dem geostrategische Ambitionen bedient werden könnten. Ein unerledigter Brexit ist nicht nur Dauerthema, sondern taugt zur Dauerkrise. Erst jüngst hat der Dissens über eine mögliche EU-Aufnahme Albaniens und Nordmazedoniens gegensätzliche Positionen zu einer fortgesetzten Osterweiterung offenbart. Schließlich setzen Frankreich und Deutschland als EU-Kernstaaten voneinander abweichende sicherheitspolitische Prioritäten, wenn es um die künftige Ausrichtung der EU geht. Präsident Macron will, dass Frankreich als europäische Macht geopolitisch wirksam wird, indem es sich auf europäische Militärmacht – vorrangig eine EU-Verteidigungsunion – stützt. Die soll sich von transatlantischen Zwängen emanzipieren und weitgehend unabhängig von der NATO agieren. Deutschland hingegen ist als europäische Führungsmacht auf geopolitische Relevanz bedacht, ohne sich von der NATO abzusetzen. Im Gegenteil, Kanzlerin Merkel betrachtet – wohl auch als Antwort an Macron – die transatlantische Verankerung mehr denn je als Geschäftsgrundlage deutscher Außen- und Sicherheitspolitik. Sie hat sich dazu am 27. November vor dem Bundestag absolut bekenntnishaft geäußert

Wo will sich von der Leyen bei solcher Polarisierung mit ihrer „Sprache der Macht“ einsortieren? Auf einem dritten Weg als dritte Kraft? Zweifel sind angebracht, dass die Kommission in Gänze ihren Ehrgeiz teilt.

Nach oben offene Eskalationsskala

Die neue Kommissionspräsidentin verfolgt offenkundig vor allem ein Ziel: das Nachzügler-Dasein der EU zu beenden. Sie soll fortan in der Lage sein, um Pfründe und Einflusssphären mitzubieten, im Nahen und Mittleren Osten ebenso wie in der Asiatisch-Pazifischen Region. Verteidigungsministerin Kramp-Karrenbauer hat bekanntlich im Blick auf Deutschland Ähnliches empfohlen. Man solle sich in die aufgeheizte Systemrivalität zwischen den USA und China einklinken. Bleibt zu hoffen – sollte von der Leyen mit ihrer „wahrhaft geopolitischen Kommission“ ebenfalls darauf aus sein –, dass in Brüssel darüber Klarheit herrscht, was das bedeutet – worauf man sich einlässt. Die EU würde nicht als neutraler Akteur in indopazifischen Raum Präsenz zeigen, sondern als Partner der USA, als Partei in einem Konflikt mit einer nach oben offenen Eskalationsskala.

Wieder einmal zeigt sich, was für von der Leyens Begriff von Geopolitik schon als Verteidigungsministerin prägend war. Sie gibt einer räumlichen Dimension den Vorzug, der Suche nach Eingreif- und Einsatzgebieten für ein vor allem militärisches Engagement weltweit. Man denke an ihren Auftritt vor der Münchner Sicherheitskonferenz Ende Januar 2014, als es hieß, Deutschland müsse bereit sein, sich außen- und sicherheitspolitisch früher, entschiedener und substanzieller einzubringen als bisher. Augenscheinlich soll das nun auch für eine EU gelten, die der Maxime gehorcht: Mehr Geopolitik wagen, heißt machtpolitisch wirksam sein.

Nur ein Aufguss

Warum nicht nach all den Erfahrungen, die es mit Geopolitik im 20. und 21. Jahrhundert gegeben hat, einmal einen Ansatz vorziehen, der frei von Herrschaftswillen und machtpolitischem Kalkül ist? Warum nicht angesichts der gescheiterten Syrien-Politik des Westens als EU ein Wiederaufbauprogramm für Syrien auflegen, das keine Vorbedingungen kennt und allein den Menschen in diesem Land zugute kommt? Wo man doch sonst menschenrechtlich unschlagbar sein will.

Weshalb nicht eine Friedensinitiative für den Jemen anstoßen, die Saudi-Arabien in die Schranken weist und sich der Konfliktmoderation durch die Vereinten Nationen anschließt. Warum nicht EU-Aufnahmeverhandlungen mit Albanien und Nordmazedonien ausnahmsweise einmal nicht mit der machtpolitischen Begründung versehen, dass sich sonst Russland und China dieser Länder annehmen?

Statt von einer „Sprache der Macht“ zu schwadronieren, könnte von der Leyen einen anderen Ton anschlagen. Wie wäre es mit einem Bewusstsein dafür, was „geopolitischen Denken“ von Großmächten bis in die Gegenwart hinein alles angerichtet hat – in Indochina, im Irak, in Afghanistan, in Libyen, in Syrien, auf dem Balkan, in Korea, in der Ukraine.

Von Emmanuel Macrons Idee einer „Neugründung Europas“ ist von der Leyen weit entfernt. Was ihr vorschwebt, ist der (wievielte?) Aufguss geopolitischen Denkens. Eine Politik der westlichen Restauration, die von der Realitäten – auch denen innerhalb der EU – schon bald korrigiert werden dürfte.

Lesen Sie mehr in der aktuellen Ausgabe des Freitag.


          

Frankreich | Arbeiten bis zur Verzweiflung

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Die Hälfte von Emmanuel Macrons Amtszeit ist um. Der Druck auf die Menschen ist nur größer geworden
Arbeiten bis zur Verzweiflung

Fisch wird über die Theke gereicht, in der Schlange vor dem Käsestand bekommen die Wartenden ein Glas Wein angeboten, etwas weiter liegen herrliche Waldpilze aus. An diesem sonnigen Herbsttag auf dem überdachten Marktplatz von Pantin scheint das Leben in Frankreich ziemlich normal. Die Gemeinde grenzt nordöstlich direkt an Paris, gehört jedoch zum Département Seine-Saint-Denis. Hier beginnen die Postleitzahlen mit „93“ und so wird auch die Gegend genannt: „Quatre-vingt-treize“, bekannt für den hohen Anteil an Sozialwohnungen, Arbeitslosen und Sozialhilfeempfängern. Die zahlungskräftigen Zugezogenen in ihren flotten Neubauten am Canal de l’Ourcq schicken ihre Kinder lieber in private Bildungseinrichtungen in Paris. Hier, genauer in der Gemeinde Bobigny, verkündete Emmanuel Macron 2016 seine Kandidatur für die Präsidentschaft. Dem Département wurde in einem Parlamentsbericht 2018 bescheinigt: Der Staat ist hier gescheitert, die Republik hat versagt, es fehlt an allem. Als dann Ende Oktober diesen Jahres ein lang erwarteter Aktionsplan der Regierung veröffentlicht wurde, mit dem Versprechen, mehr Personal im öffentlichen Dienst zu rekrutieren, hatte die Aktualität die Politik längst eingeholt.

Völlig erschöpft

Ein paar hundert Meter vom Markt die Straße hinauf, in der Rue Méhul Nummer 30, steht man vor dem grauen, spitz zulaufenden Art-déco-Eingang einer öffentlichen Grundschule. Am Montagmorgen des 23. September ging von hier aus ein Notruf bei der Feuerwehr ein. Die Schuldirektorin Christine Renon hatte sich zwei Tage zuvor in der Eingangshalle in den Tod gestürzt. „Das ganze Viertel stand unter Schock“, erzählt eine Anwohnerin. „Es war furchtbar, zu erfahren, wie sehr sie innerlich unter der Arbeit hier gelitten hat.“ Ihren Leidensdruck beschrieb die 58-Jährige in einem Abschiedsbrief an die Schulbehörde und andere Schulleiter. „Heute, am Samstag, bin ich völlig erschöpft aufgewacht. Nur drei Wochen nach Ferienende“, schrieb sie. „Diese vielen kleinen Nichtigkeiten, die 200 Prozent unserer Zeit beanspruchen. Ich habe kein Vertrauen in die Unterstützung und den Schutz, die unsere Behörde uns bieten müsste.“

Steigende Arbeitsbelastung bis zur Verzweiflung: Geschichten wie die Renons hört man in Frankreich seit Jahren. Wenn Angestellte des öffentlichen Dienstes sich das Leben nehmen, ob Lehrer, Pfleger in Krankenhäusern oder – allein in diesem Jahr 54 – Polizisten, dann geht ein kurzer Aufschrei durch das Land. Ein Land, das unter Dauerstress steht: verängstigt durch Terroranschläge, mit einer sich stark verändernden politischen Landschaft und einer Regierung, die glaubt, der Staat müsse sich zurückziehen, um private Unternehmen und Wettbewerb zu stärken.

„Zwar bestand schon vor Macron ein großer Notstand, aber seit er am Ruder ist, hat sich der Druck noch verschlimmert“, sagt Sabrina Ali Benali. Auf den Caféstuhl im 20. Pariser Arrondissement hievt die zierliche 33-Jährige mit den dunklen Locken einen wuchtigen Rucksack mit kompletter technischer Ausstattung für ihre Nachtschicht. In einer Stunde ist die Mutter, politische Aktivistin und Buchautorin wieder für neun Stunden mobile Notärztin in der Hauptstadt. „Erst gestern war mir zum Heulen zumute“, beginnt sie ohne große Vorrede. „Eine alte Frau mit einem schlimmen Abszess am Bauch, mit Nierenversagen, Diabetes und hohem Blutdruck wollte ich direkt ins Krankenhaus schicken, aber sie ließ sich nicht überreden. Sie habe das mehrmals durch: Stundenlanges Warten, und dann wird man einfach nach Hause geschickt.“

Sabrina Ali Benali erreichten Hunderte Erfahrungsberichte aus Krankenhäusern, seit sie im Januar 2017 auf Youtube ihren Frust herausließ. Elf Millionen Views innerhalb von zwei Wochen erzielte das Video, mit dem sie der damaligen Gesundheitsministerin den Spiegel vorhalten wollte. Ein paar Monate später erschien ihre Analyse der alarmierenden Zustände in dem Buch La révolte d’une interne („Die Revolte einer Assistenzärztin“). Wann immer sie es schafft, demonstriert sie auf der Straße, zuletzt am 15. Oktober an der Seite von Feuerwehrleuten, „mit denen wir ja in einem Boot sitzen“. Mittlerweile streiken über 200 Pflegeeinrichtungen landesweit für mehr Betten und mehr Stellen. Weil Krankenhäuser immer mehr wie Unternehmen wirtschaften sollen, habe sich das Klima verschärft.

Doch darüber hinaus sei es Macrons arrogante, verhöhnende Art, die Benali wütend mache. Als gäbe es Probleme nur, weil man sich nicht genug anstrengt in der Start-up-Nation, die sich der Präsident erträumt. „Jetzt hat er Scheindebatten losgetreten, über das Kopftuch, über Einwanderung. Nur um davon abzulenken, dass er seit den Gelbwesten nichts für mehr soziale Gerechtigkeit getan hat.“ Für ihre dreijährige Tochter wünscht sie sich eine solidarischere Gesellschaft. Aus diesem Grund habe sie noch nicht das Handtuch geworfen. Ein Blick auf ihr Handy: „Hier stehen jetzt schon 67 Einsätze in der App und wir sind elf Ärzte. Das wird sportlich heute!“ Dann schultert sie den schweren Rucksack, startet ihr Auto und braust in die Pariser Nacht.

Am Steuer sitzt auch Alexandra Ferré. Heute hat sie noch anderthalb Stunden von Toulouse zu dem Dörfchen Couthures am Ufer der Garonne vor sich. Jeden Monat legt die resolute junge Frau mit dem schwarzen Bubikopf bis zu 6.000 Kilometer nur im Südwesten Frankreichs zurück. Sie kontrolliert die Belieferung von Transportunternehmen mit Kraftstoffen, eine Männerdomäne, in der sie sich ihren Platz erkämpft hat. Als am 17. November 2018 über 300.000 Autofahrer landesweit protestierten, stand auch Alexandra, gemeinsam mit ihrer Mutter, an einem Kreisverkehr. „Es war das erste Mal überhaupt, dass ich demonstriert habe“, sagt die 31-Jährige. „Wir waren um die 60 Leute. Wir grillten zusammen, wir tranken. Die Menschen zeigten Verständnis für uns, auch wenn einige wegen der Straßensperren genervt waren.“ Die erfahrene Solidarität, die überwundene Scham, die Angst, nicht über die Runden zu kommen, das habe die Leute zusammengebracht.

„So verloren wie wir alle“

Schnell jedoch sei das Engagement schwieriger geworden: „Durch die Medien war die Bewegung stigmatisiert. Man wollte uns weismachen, die Gelbwesten, das seien überwiegend Faschos. Ich hatte Angst vor beruflichen Konsequenzen, wenn ich weiter dabeibleibe“, gesteht sie. Als dann Macron Anfang 2019 die „große nationale Debatte“ lanciert hat, eine Art Promo-Tour in allen Ecken das Hexagons, schien er eine neue Nähe zu seinen Bürgern zu suchen. Zuhören, seine Politik erklären, statt sie nur durchzupeitschen. Nachdem die Regierung die geplante Steuererhöhung auf Eis gelegt hatte, nahm die Beteiligung an den Protesten von Woche zu Woche, von Monat zu Monat ab. Nur ein Dutzend Gelbwesten, der harte Kern, macht in Couthures heute noch weiter. Alexandra sagt: „Macron wirkt für mich irgendwie verloren. So verloren wie wir alle.“ Ein kurzes Zögern. „Oh, jetzt hätte ich fast einen Blitzer übersehen!“ In ihrer Familie seien immer alle Kommunisten gewesen, lacht sie. Dass Marine Le Pens Rassemblement National (RN) so erfolgreich ist, kann sie trotzdem verstehen. Es sei die Wut, dieses diffuse, schwer zu beschreibende Gefühl: „Irgendwie wollen wir Franzosen ja, dass sich etwas verändert, nur weiß keiner, in welche Richtung!“

Samuel Leré ist einer, der weiß, in welche Richtung er Frankreich verändern will. Vor einem Espresso im einst von Intellektuellen wimmelnden Viertel Saint-Germain übergibt er eine Broschüre mit Vorschlägen, deren Ziel es ist, internationale Handelsbeziehungen in den Dienst der Energiewende zu stellen. Große Themen für den freundlich lächelnden 27-Jährigen, der schon in Irland, Litauen und Brasilien gelebt hat. „Ich habe das Glück, jeden Tag gern zur Arbeit zu gehen, etwas Sinnvolles zu machen“, sagt er. In Zeiten von „Fridays for Future“ ist er als einer der Sprecher der Stiftung „Nicolas Hulot – pour la Nature et l’Homme“ viel gefragt. Die große Beteiligung an den Klimamärschen sei ein Zeichen, dass die Klimakrise in den Köpfen der Franzosen angekommen ist. Die Gefahr, Klima- und Sozialpolitik gegeneinander auszuspielen, ist ihm bewusst: „Wir müssen verstehen, dass soziale Gerechtigkeit, wie sie die Gelbwesten fordern, Hand in Hand mit Klimagerechtigkeit geht. Die beiden Anliegen sind keine Gegensätze!“ Samuel ist optimistisch, auch wenn sein Chef, Nicolas Hulot, Macrons Regierung den Rücken gekehrt hat, weil er als Umweltminister nichts gegen Lobbys und den Vorrang der Wirtschaft vor der Umwelt ausrichten konnte. Politik könne noch immer pragmatische Lösungen auf demokratischem Wege finden, ohne Revolution. Die Gelbwesten haben vielleicht gerade noch rechtzeitig die großen Unterschiede zwischen urbaner und ländlicher Bevölkerung deutlich gemacht. Noch sei Zeit zum Handeln. „Meine Familie lebt auf dem Land, auch da setzt ein Umdenken ein. Klar, ich bin immer noch der Paris-intello, der sich über zu viel Plastikverpackungen auf dem Tisch beschwert. Aber wenn man anfängt, miteinander zu reden, ich von meinen Ideen berichte, dann gibt es auch viel Zustimmung, da spielt es gar keine Rolle, welche Partei man gewählt hat.“

Generalstreik am 5. Dezember

Die traditionellen politischen Lager gibt es seit Macron tatsächlich nicht mehr – sieht man von Marine Le Pen ab, der nahezu einzigen Konstante im sich verändernden Parteiengefüge. Eine zersplitterte Linke schafft es kaum, sich zusammenzuraufen. Die Konservativen rudern entkräftet, weil Macron ihnen kaum noch Angriffsflächen bietet. Schließlich ist er, so sagte es der Ex-Parteichef der Konservativen, Jean-François Copé, „der rechte Präsident, den wir nicht erwartet haben“.

Nun liegen weitere zweieinhalb Jahre vor diesem Präsidenten, der angetreten war, um die alte Bipolarität „links vs. rechts“ zu beenden, und stattdessen versucht, eine neue Zweiteilung zu etablieren: „progressiv vs. national“: alle für mich und gegen Le Pen. Damit macht er die anderen politischen Kräfte zu Nebendarstellern. Selbst in Richtung rechts außen blinkt er seit Neuestem, hat nach dem Vorbild Nicolas Sarkozys wieder die Themen Immigration und Kommunitarismus für sich entdeckt. Ein durchschaubares Ablenkungsmanöver von einer anderen Großbaustelle: Mit der Rentenreform will die Regierung 42 Sonderregelungen vereinheitlichen und hat damit nahezu alle Berufsgruppen gegen sich.

„Es wird keine Form der Schwäche oder des Entgegenkommens geben“, ließ er Ende Oktober in Hinblick auf die Reform wissen. Doch die Wut kann auf den Straßen, an Kreisverkehren, in Krankenhäusern und Feuerwehrkasernen jederzeit aufflammen. Am 17. November feiern die Gelbwesten ihren ersten Jahrestag. Sie haben sich dem für den 5. Dezember ausgerufenen Generalstreik der Gewerkschaften angeschlossen. Unbefristet. Dann werden in Frankreich nicht nur die Eisenbahnen stillstehen. Vielleicht erinnert sich Macron nur vage an das Jahr 1995. Damals war er 18, und auch damals ging es um die Reform der Rente. Drei eisige Herbstwochen lang ging nichts mehr, aber im Stillstand war das Land vereint. Am Ende knickte die Regierung Alain Juppés ein, und das Weihnachtsfest verlief friedlich.

Ganz sicher wird Sabrina Ali Benali auch in diesen Tagen nachts durch Paris fahren. 1.000 Kilometer entfernt steuert Alexandra Ferré das Auto an Kreisverkehren vorbei. Mag sein, dort stehen Menschen in gelben Westen und grüßen die Vorbeifahrenden mit einem Glühwein in der Hand. Samuel Leré wird beim nächsten Klimamarsch am 29. November in Paris dabei sein. Dann wird auch der Wochenmarkt in Pantin gut besucht sein. Jetzt schon steht die Straße hinauf, vor der Grundschule, in der Christine Renons starb, ein Bauschild. Demnächst soll die Betonfassade renoviert werden.

Romy Straßenburg ist freie Korrespondentin in Frankreich und hat zuletzt das Buch Adieu liberté. Wie mein Frankreich verschwand veröffentlicht

Lesen Sie mehr in der aktuellen Ausgabe des Freitag.


          

Frankreich | Wir klären das auf der Straße

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Die neuerliche Stärke der feministischen Proteste gegen Femizide ist kein Zufall
Wir klären das auf der Straße

Das sind 137 zu viel: 137 Frauen wurden in Frankreich 2019 bereits von ihren Ehemännern oder (Ex-)Partnern getötet. Ein Meer aus Violett zog deshalb am vergangenen Samstag durch französische Städte, Farbe des Protests von mehr als hunderttausend Menschen gegen diese extremste Form von Frauenhass. Auf den französischen Transparenten standen die Vornamen und das Alter der ermordeten Frauen als Mahnung und Gedenken. Über 70 Organisationen hatten anlässlich des 25. Novembers, des „Internationalen Tags zur Beseitigung von Gewalt gegen Frauen“, zu den Protesten aufgerufen. Frankreich gehört zu den Ländern, in denen überproportional viele Fälle von häuslicher Gewalt zu verzeichnen sind: Im letzten Jahr waren es 220.000, in Deutschland laut Bundeskriminalamt 140.000 Taten.

Französischen Feministinnen ist es gelungen, mit dem Hashtag #noustoutes („Wir alle“) eine mediale Welle ins Rollen zu bringen. Ihr Erfolg war weitaus einschneidender als der in Deutschland initiierte Slogan #keinemehr. Das hat zum einen mit dem Zusammenspiel der immer wieder aufkommenden #metoo-Fälle zu tun. So brach kürzlich auch die prominente Schauspielerin Adèle Haenel, aktuell im Film Porträt einer jungen Frau in Flammen zu sehen, ihr Schweigen über erlittene Belästigung. Zum anderen aber ist „die Straße“ in Frankreich ein Ort, der weit mehr für das Austragen gesellschaftlicher Auseinandersetzungen genutzt wird als in Deutschland.

Seit Monaten machen Bürger ihrem Ärger über herrschende Verhältnisse Luft, ob Gelbwesten- oder Klimabewegung, ob Krankenhausmitarbeiter und Feuerwehrleute, ob Polizisten oder Angestellte des öffentlichen Dienstes. Kaum ein Tag vergeht, an dem keine Demonstration durch Pariser Straßen zieht. Schon in der Gelbwestenbewegung spielten Frauen eine besondere Rolle, weil sie mit einer neuen Selbstverständlichkeit Präsenz zeigten. Eine wiedererwachte Protestkultur.

Dazu kommt, dass feministische Debatten im öffentlichen Diskurs verstärkt sichtbar sind, etwa im Fall der verschärften Gesetzgebung bei Anmache auf offener Straße, die manchen Frauen als überzogen erschien. Nicht zuletzt ist mit der von Macron berufenen Gleichstellungsministerin Marlène Schiappa eine charismatische, junge Politikerin aufgestiegen, der es gelungen ist, den Unzulänglichkeiten bei der Geschlechtergleichheit Gehör zu verschaffen.

Doch die gesteigerte Aufmerksamkeit allein reicht den Aktivistinnen nicht aus. Die meisten zeigten sich enttäuscht, als die Regierung am Montag einen Aktionsplan vorstellte, dem eine mehrere Monate andauernde Aussprache mit VertreterInnen von staatlichen und privaten Organisationen vorausgegangen war. Zwar sieht das Programm vor, Waffen gewalttätiger Männer leichter konfiszieren zu können oder Tätern elektronische Fußfesseln anzulegen. Doch die von Premierminister Edouard Philippe angekündigten Investitionen von 361 Millionen Euro für 2020 bleiben weit hinter der 1 Milliarde zurück, die als eine Art „Marshall-Plan“ zur Bekämpfung von Gewalt gefordert worden war. Immerhin gehören zu den geplanten Maßnahmen auch der Ausbau einer Notruf-Nummer für Betroffene, die psychologische Betreuung von gewalttätigen Männern sowie die Schaffung von 1.000 zusätzlichen Plätzen in Frauenhäusern. Wichtig ist nun, dass die Solidarität und das Selbstbewusstsein der Straße auch in der Privatsphäre der Frauen nachhallen. Dort, wo nur sie selbst „Stop!“ sagen können.

Lesen Sie mehr in der aktuellen Ausgabe des Freitag.


          

3 Key Metrics Suggest Bitcoin Price Has Completed Its Macro Bear Cycle

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Via CoinDebate.com
          

Why are you bullish on Bitcoin? Why do you HODL?

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Bitcoin - The Currency of the Internet     •     December 1, 2019, 11:29 pm
Simple as that. I'm curious submitted by /u/jtwoods [link] [comments]
Bitcoin - The Currency of the Internet     •     December 1, 2019, 2:13 pm
Anyone have any experience taking their income in Bitcoin? I've done a bit of research on potentially using BitWage but would be curious to hear from anyone that's done this. Are there other,…
Cointelegraph.com News     •     December 1, 2019, 3:36 pm
The top performers of the past seven days indicate buying at lower levels. At what levels will they signal a trend change? Let’s analyze the charts
Cointelegraph.com News     •     December 1, 2019, 9:29 pm
Several key metrics like the RSI, MACD, and CME Futures gap point toward a bullish rally for Bitcoin price over the coming week
Crypto New Media     •     December 1, 2019, 9:26 pm
Crypto New Media Press Ripple’s XRP saw its value soar parabolically to an all-time high of almost $ 3.5. This happened during the massive bull run of 2017. Since then the token has lost 92% of its…
https://www.coindebate.com/

          

Next Time Somebody Tells You Crypto Is a Bubble, Show Them This

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Crypto New Media     •     December 1, 2019, 10:08 pm
Crypto New Media Press Travel We spent billions to get from A to B. The International Air Transport Association (IATA) estimates net profits in 2019 at $35.5 billion. I don’t even want to look into…
Crypto New Media     •     December 1, 2019, 10:18 pm
Crypto New Media Press Ethereum’s price action has been strikingly similar to Bitcoin’s over the past several days and weeks, with ETH’s correlation to BTC growing stronger as the volatility seen…
Crypto New Media     •     December 1, 2019, 10:04 pm
Crypto New Media Press Whilst the Bitcoin price (BTC) action may seem bearish to some, the leading digital asset has several bullish indicators that hint towards an imminent recovery. As Bitcoin…
Bitcoin - The Currency of the Internet     •     December 1, 2019, 7:50 pm
So my bircoinqt app has been downloading and syncing the chain for 2 weeks now (I'm only 60% through ...yeah wtf?) My question is should I update to the recently released version now or should I…
https://www.coindebate.com/

          

Trump to Face NATO in Increasing Disarray

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https-::www.newsmax.com:headline:trump-nato-macron-turkey:2019:12:01:id:943955: (https://www.newsmax.com/headline/trump-nato-macron-turkey/2019/12/01/id/943955/) *What was conceived as a celebration for one of the world’s most important military alliances risks becoming a show of disunity -- and...
          

Des Deux Mondes Octobre 2017 Qu Est Ce Que Le Macronisme Franz Olivier Giesbert Richard Millet Philippe Raynaud Jean Paul Clement Michel Delon Sebastien

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Des Deux Mondes Octobre 2017 Qu Est Ce Que Le Macronisme Franz Olivier Giesbert Richard Millet Philippe Raynaud Jean Paul Clement Michel Delon Sebastien
          

ALZHEIMER L'EPIDEMIA SILENZIOSA di Marcello PAMIO Come prevenire e curare la demenza

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ALZHEIMER L'EPIDEMIA SILENZIOSA Come prevenire e curare la demenza di Marcello PAMIO (UNO editori www.unoeditori.com) descrive una delle patologie più tremende che l'uomo abbia mai conosciuto: una malattia silente ma in grado di devastare non una persona ma l'intera famiglia!
Il cervello è l'organo più enigmatico e complesso dell'universo e forse proprio per questo è l'unico del corpo umano il cui funzionamento ancora sfugge alla nostra comprensione.
Le cifre che lo descrivono sono a dir poco astronomiche: in un volume di 1.500 centimetri cubi si racchiudono 100.000 milioni di neuroni che utilizzano fino a 19.000 dei 30.000 geni che compongono il genoma umano.

I neuroni si collegano tra loro formando un miliardo di connessioni per ogni millimetro cubo di corteccia cerebrale. Per non parlare delle cellule gliali di supporto che sono addirittura 10 volte tanto. Eppure questa splendida macchina può andare incontro a declino cognitivo e demenza tra cui il morbo di Alzheimer, la più diffusa patologia sopra una certa età.
I malati di Alzheimer al mondo sono 47 milioni e questa cifra è destinata a raddoppiare ogni 20 anni. Quali sono le cause di questa subdola malattia che lentamente cancella la coscienza? È possibile prevenirla e/o curarla?

A rispondere a queste domande una quindicina tra medici e ricercatori, che oltre a dare la loro interpretazione, propongono interessanti strumenti di intervento e percorsi terapeutici.
Con questo libro scopri: quali potrebbero essere le cause scatenanti della demenza; come poter intervenire preventivamente;
i più interessanti percorsi terapeutici naturali... e molto altro ancora.
Leggi anche altri post sullo stesso argomento:

RISPOSTA ALL'ALZHEIMER di Marwan SABBAGH
Riduci il tuo rischio e mantieni sano il tuo cervello

UNA PALESTRA PER LA MENTE 2 di Donata GOLLIN, Arianna FERRARI e Anna PERUZZI Nuovi esercizi di stimolazione cognitiva per l'invecchiamento cerebrale e le demenze

ATTACCO ALLE MALATTIE DEL CERVELLO di Paolo GIORDO
Prevenire e curare con metodi naturali: sclerosi multipla, Parkinson, Alzheimer, miastenia gravis, SLA, fibromialgia, sindrome da fatica cronica




Marcello Pamio è uno scrittore e insegna nutrizione in diverse scuole di naturopatia. Dal 1999 gestisce il sito internet www.disinformazione.it.
È autore di diversi saggi di successo tra cui ricordo: Il lato oscuro del Nuovo Ordine Mondiale, Manifesto contro la televisione, Diabete, La vita inizia prima della nascita (scritto insieme a Marisa Bettio).
Con Uno editori ha già pubblicato: La fabbrica dei malati, Dietro le quinte, Cancro S.P.A., Il marketing della pazzia, Vaccinazioni.

Leggi 2 estratti da ALZHEIMER L'EPIDEMIA SILENZIOSA Come prevenire e curare la demenza di Marcello PAMIO:

ALZHEIMER: SINTOMI, DIAGNOSI E PREVENZIONE Scopri come si sviluppa e come si può limitare questa malattia neurodegenerativa

UNA MALATTIA SUBDOLA E INVISIBILE

L'Alzheimer, più che una patologia, potrebbe essere interpretato come una sorta di "meccanismo di difesa". La malattia di Alzheimer può essere definita una "patologia neurologica che viene considerata la principale forma di "demenza" che esordisce, tendenzialmente, nella terza età.
Si manifesta con la perdita graduale e progressiva della memoria, delle facoltà intellettive e, nelle ultime fasi, anche del controllo delle funzioni fisiologiche."
Sembra esserci una predisposizione genetica e una frequente associazione con una forte depressione, non risolta, tra i 50 e i 65 anni. Il 7 aprile 2017 è stata resa nota la scoperta:
"l'origine dell'Alzheimer: non è nell'area del cervello associata alla memoria che va cercato il responsabile del morbo. All'origine della malattia ci sarebbe, invece, la morte dei neuroni nell'area collegata anche ai disturbi dell'umore." Prof. Marcello D'Amelio

Una persona malata di Alzheimer o di una patologia psichiatrica grave come la schizofrenia è pressoché immune dal tumore. Il libro strutturalmente è diviso in 2 parti.
Nella prima parte viene spiegato cos'è e cosa non è l'Alzheimer. La seconda parte risponde ad alcune domande come per esempio: "Qual è la causa o le cause dell'Alzheimer?"; "Esiste una cura?".
L'autore ha intervistato una quindicina di medici e ricercatori con lo scopo di inquadrare il fenomeno nella sua complessità e globalità: vuole condividere queste conoscenze non per dare false illusioni ma per mantenere accesa e viva la fiammella della speranza:
"Se infine teniamo conto che per la medicina ufficiale l'Alzheimer è una patologia neurodegenerativa assolutamente incurabile, per la quale non esiste nessuna cura... cosa rischiamo cambiando visione e prospettiva?" Marcello Pamio

Il cervello, esattamente come per un muscolo, va tenuto costantemente in allenamento con stimoli adeguati (letture, immaginazione, visualizzazione, musica, cruciverba, ecc.) alternati a profondo riposo e a una nutrizione corretta.
Il declino cognitivo è una delle maggiori preoccupazioni della popolazione anziana e il morbo di Alzheimer è la maggiore causa di declino cognitivo correlato all'età.
L'Italia è la prima al mondo per numero di casi. Secondo un nuovo studio la malattia potrebbe essere la terza causa di morte negli Stati Uniti. Inoltre le donne sono l'epicentro di questa epidemia: sono donne il 65% dei pazienti.

Il termine "demenza" viene usato per descrivere un declino delle facoltà mentali abbastanza grave da interferire con la vita quotidiana. La perdita di memoria è solo un esempio di tale declino.
Una persona anziana, anche molto vecchia, non per forza di cose deve conoscere la demenza: infatti in certe popolazioni ultracentenarie come gli Hunza la demenza è sconosciuta.
La malattia prende il nome dal dott. Alois Alzheimer (1864-1915), psichiatra e neuropatologo tedesco che per la prima volta ne 1907 ne descrisse i sintomi e gli aspetti neuropatologici.
La diagnosi precoce è molto importante, non esistono farmaci in grado di fermare e far regredire la malattia per cui tutti i trattamenti oggi disponibili puntano solo al contenimento della sintomatologia con risultati scarsi ma inducendo effetti collaterali.

Una perdita di memoria momentanea o dimenticare qualche fatto della vita non significa avere il morbo di Alzheimer o un altro tipo di demenza!
Una vera demenza interferisce negativamente con la memoria, la comunicazione e il linguaggio, la capacità di concentrarsi e di prestare attenzione, il ragionamento, il giudizio e la percezione visiva.
Se si vuole prevenire la demenza o migliorare la condizione mentale in caso di malattia conclamata, è obbligatorio limitare la fruizione da apparecchi televisivi e dalle varie "diavolerie" elettroniche in generale per far posto ad altre attività dinamiche.
La malattia non fa distinzioni e non risparmia neppure le persone ricche, intelligenti e molto famose tra cui: il filosofo Kant, Emil Cioran, attori come Robin Williams, Peter Falk, Rita Hayworth, Lauretta Masiero, Sean Connery; politici come Ronald Reagan, Margaret Thatcher e molti altri.

Gli otto tipi di danni correlati alla frequenza del 5G (nuovo standard di comunicazione cioè la quinta generazione) sono i seguenti: 1) danni cellulari al DNA (rottura del filamento singolo del DNA, rottura del filamento doppio, ossidazione delle basi del DNA);
2) diminuzione della fertilità maschile e femminile, aumento di aborti spontanei, abbassamento di ormoni come estrogeni, progesterone e testosterone; 3) danni neurologici e neuropsichiatrici; 4) apoptosi e morte cellulare;
5) stress ossidativo e aumento dei radicali liberi (responsabili della maggior parte delle patologie croniche); 6) effetti ormonali; 7) aumento del calcio intracellulare; 8) effetto cancerogeno sul cervello, sulle ghiandole salivari e sul nervo acustico.

Oggi la dieta chetogenica (dr. Joseph Mercola) viene sempre più spesso applicata in patologie neurologiche come la depressione, l'Alzheimer, il Parkinson, ecc.: inoltre bere molta acqua è importante per mantenere in salute il cervello.
Una ricerca che studiava i composti attivi nel tè verde ha stabilito che le catechine contenute non solo sono antiossidanti e neuroprotettive ma addirittura stimolano il cervello a produrre più neuroni.
E' stato dimostrato che il tè verde ha implicazioni interessanti nel trattamento delle malattie neurodegenerative come il morbo di Alzheimer, il morbo di Parkinson e di Huntington.
Non esiste la panacea per tutti i mali dell'uomo e infatti per l'Alzheimer ufficialmente non c'è una cura. La cosa migliore da fare è la prevenzione: prima si interviene e migliori saranno i risultati ottenuti.

Se esiste un filo conduttore che lega tutti gli interventi del libro, sicuramente è il consiglio di CAMBIARE QUANTO PRIMA LO STILE DI VITA!
Per adottare uno stile di vita più salutare bisogna imparare a comprendere quali sono i grassi utili al cervello e quali sono dannosi. Secondo il dott. David Perlmutter l'Alzheimer è prevenibile attraverso una dieta appropriata.

Le diete ad alto contenuto di grassi sono associate a un rischio ridotto del 44%. Questa combinazione, pochi zuccheri e carboidrati e molti grassi salubri, è la chiave di lettura per affrontare non solo l'Alzheimer ma anche il diabete e le malattie cardiache!
Il libro di Neal Barnard Super Cibi per la mente ci indica che per gestire al meglio la salute del proprio cervello, oltre alla ginnastica mentale e una corretta alimentazione, bisogna praticare la ginnastica fisica che è importantissima.

Alcune delle mie citazioni preferite da ALZHEIMER L'EPIDEMIA SILENZIOSA Come prevenire e curare la demenza di Marcello PAMIO:

"Più esistenza, meno assistenza!" Dalla prefazione del prof. Ivano Spano
"Tu, i tuoi ricordi e le tue ambizioni non siete altro che il comportamento di un vasto insieme di neuroni e delle loro molecole." Francis Crick
"Un uomo può reputarsi felice se il suo cibo è anche la sua medicina." Henry David Thoreau
"Ogni uomo, se lo decide, può essere lo scultore del proprio cervello."
Santiago Ramon y Cajal, Premio Nobel per la Medicina 1906



Un caro saluto. Raffaele Ciruolo

          

LA SCELTA ANTITUMORE del dott. Giuseppe DI BELLA Prevenzione, terapia farmacologica e stile di vita

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LA SCELTA ANTITUMORE Prevenzione, terapia farmacologica e stile di vita di Giuseppe DI BELLA (Macro edizioni www.gruppomacro.com UNO editori www.unoeditori.com) è un libro indispensabile per saperne di più sul Metodo Di Bella, un valido metodo scientifico osteggiato dal sistema.
Ti spiega in cosa consiste oggi la terapia e quali sono i risultati concreti supportati da una documentatissima letteratura scientifica.
La multiterapia ideata dal prof. Luigi Di Bella (padre di Giuseppe) riscuote ampi e autorevoli riconoscimenti internazionali con innumerevoli testimonianze dei miglioramenti dei malati.

Questo è un libro 4D: ovvero un libro che va oltre la carta. Oltre alle pagine da leggere trovi infatti una serie di contenuti multimediali extra di approfondimento.
All'interno del libro ci sono semplici istruzioni per accedere a questi contenuti da qualsiasi dispositivo: PC, tablet, smartphone e smart-TV.
Leggendo questo volume scoprirai: cos'è la multiterapia dei tumori; qual è realmente l'importanza dell'alimentazione e dell'ambiente per la prevenzione e la cura;
quali sono gli agenti cancerogeni interni all'organismo e quali quelli esterni, che possono essere pericolosi per la nostra salute; le possibilità concrete di abbattere l'incidenza, contrastare l'insorgenza e la progressione del tumore.

Lo scopo è aiutarti a districarti tra le informazioni frammentarie o ambigue e a riconoscere quelle utili a identificare le possibili cause, a prevenire o a guarire dalla malattia.
Nel 1996 (dopo gli esiti positivi del Metodo Di Bella) si arrivò alla nota sperimentazione e al suo falli­mento. Ma la falsificazione della sperimentazione (viziata da anomalie e irregolarità che qui vengono documentate) non ha però portato alla delegittimazione del metodo stesso, che è e rimarrà un documen­tato atto di accusa contro la dittatura terapeutica.
I benefici della multiterapia infatti sono avvalorati da un crescente numero di conferme sulle banche dati medico-scientifiche internazionali.

"Non ho il minimo merito nelle ricerche e nelle scoperte di mio padre, mia unica ambizione è diffondere il Suo Metodo, divulgarne la concezione terapeutica, proseguire nella realizzazione del Suo obiettivo primario:
sollevare dalla disperazione e dalla sofferenza, ridare fiducia, sorriso e speranza a tanti sofferenti disperati, riportando la medicina dall'attuale deriva commerciale e speculativa all'antica dignità di arte etica, ippocratica, spirituale, unica Via che attraverso la Verità porta alla Vita." Giuseppe Di Bella



Giuseppe Di Bella dopo la laurea in medicina presso l'Università di Modena nel 1965 ottiene il diploma di specializzazione in ORL (otorinolaringoiatra) nel luglio 1968 presso l'Università di Bologna. Dal marzo 1967 è iscritto all'Albo dei Medici Chirurghi.
È stato primario di chirurgia maxillofacciale e primario ORL nel 1975. Dal 1975 al 1984 è responsabile del servizio ORL presso l'ospedale di Budrio-Bologna. Poi svolge attività di libero professionista.

Dal 1968 ha svolto circa 15.000 interventi in anestesia generale nell'ambito della specialità ORL. È stato correlatore, col professor Luigi Di Bella, della monografia "Cancro, siamo sulla strada giusta?".
Ha partecipato a moltissimi congressi nazionali e internazionali ed ha all'attivo tantissime pubblicazioni tra cui il libro Il Metodo Di Bella.
È il Presidente della "Fondazione G. Di Bella - ONLUS" per lo studio e il trattamento delle patologie neoplastiche e degenerative.

Leggi l'introduzione del libro LA SCELTA ANTITUMORE di Giuseppe Di Bella e scopri un metodo tanto rivoluzionario quanto scomodo:

UNA FIGURA SCOMODA

I CONTENUTI EXTRA DEL LIBRO LA SCELTA ANTITUMORE:
VIDEO-INTERVISTA AL DOTT. DI BELLA; perché ci furono manifestazioni di piazza che chiedevano che venisse approvato il Metodo Di Bella;
la scientificità della cura: le pubblicazioni sulle riviste internazionali; i retroscena della sperimentazione del Metodo Di Bella: le irregolarità e i criteri di arruolamento;
sperimentazione Di Bella: l'inchiesta di Guariniello; i risultati positivi della multiterapia nonostante il boicottaggio; la precocità della diagnosi e il fallimento della chemioterapia;
la carne: pro e contro; i risultati del Metodo Di Bella oggi: l'efficacia della melatonina... e tanto altro!

Secondo il prof. Carlo Ventura (autore della prefazione) "il cancro non è una singola entità ma un gruppo di patologie correlate.
La sua stessa complessità emerge dalle recenti acquisizioni che vedono in alterazioni della capacità differenziativa e proliferativa delle cellule staminali residenti in ogni tessuto del corpo umano una causa fondamentale nella disseminazione metastatica delle neoplasie, al punto di parlare di "cancer stem cells" per identificare una popolazione probabilmente eterogenea di elementi staminali che ha perso la capacità di garantire il potenziale di autoriparazione dei nostri tessuti trasformandosi addirittura in elementi che promuovono una strada spesso di non-ritorno come la diffusione metastatica...
La prevenzione resta sicuramente una strategia essenziale, un approccio così importante in ambito biomedico da essere considerato sempre attuale e necessario anche quando il progresso della terapia e della diagnosi dovesse arrivare a porre risoluzioni definitive, come si spera accada presto per il problema del cancro."

In questa grande opera di Giuseppe Di Bella vengono affrontati con estremo rigore, chiarezza e modernità i temi della prevenzione primaria e secondaria dei tumori.
L'autore si concentra in particolare sull'importanza e sulla possibilità di effettuare una prevenzione farmacologica dell'insorgenza tumorale.
Egli analizza a fondo le strategie introdotte negi ultimi anni, avendo come target molecolare percorsi specifici. Presenta il Metodo Di Bella spiegandone le basi razionali, i percorsi storici, l'iter travagliato a livello istituzionale, le applicazioni nell'oncologia, i risultati ottenuti.
La scelta antitumore è un libro davvero interessante non solo per gli "addetti ai lavori" ma anche per chi vuole approfondire un problema in crescita e drammatico.

Questo libro nasce dalla profonda e sentita esigenza di far risparmiare a tanti gravi sofferenze e/o sollevarli dal tragico calvario del cancro, assolutamente inimmaginabile per chi non lo ha vissuto.
Ha il dovere morale, l'esigenza etica e scientifica di trasmettere, diffondere e valorizzare un patrimonio unico di conoscenze mediche e acquisizioni scientifiche frutto dell'intera vita del padre di Di Bella, totalmente, appassionatamente dedicata alla ricerca, allo studio e al progresso terapeutico.
Citando Sant'Agostino: "Nessuno può essere veramente amico dell'uomo se non è innanzi tutto amico della verità."
Un eminente medico e ricercatore, Sergio Stagnaro, scienziato noto a livello internazionale, definì il prof. Luigi Di Bella "L'ultimo grande clinico, un gigante in un mondo di nani".

Questo "Metodo" creato oltre 40 anni fa dal prof. Di Bella fu così da lui definito: "Essere essenziale più che l'inattuabile e immaginaria uccisione di tutti gli elementi neoplastici, la realizzazione di tutte le condizioni, note, possibili e non dannose entro determinati limiti, atte a ostacolarne lo sviluppo, fino alla morte per apoptosi, sopratutto attraverso l'intergioco fra i numerosi fattori di crescita.
L'essenziale sta nell'attivare tutti gli inibitori dei noti fattori di crescita alle dosi e con tempestività e tempi opportuni. Il protocollo MDB (Metodo Di Bella) è nato in quest'atmosfera, quella della vita e non dall'intossicazione e morte delle cellule, metodo che asseconda ed esalta le reazioni vitali senza ricercare con precisione statistica le dosi più opportune per uccidere.
Il tumore (dagli stadi iniziali, pretumorali alle fasi avanzate, metastatiche) è deviazione dalla vita normale, per cui occorre riportare le reazioni deviate alla norma attraverso l'esaltazione di tutti quei mezzi che la Fisiologia considera essenziali per la vita...

non esiste né esisterà alcun trattamento chemioterapeutico citotossico (né monoterapia) in grado di prevenire o guarire un tumore ma unicamente un Metodo, una multiterapia razionale e biologica, un complesso di sostanze sinergiche e fattorialmente interattive, singolarmente dotate di attività antitumorale atossica, che sequenzialmente o contemporaneamente agiscano centripetamente sulla miriade di reazioni biologiche della vita tumorale riconducendo gradualmente alla normalità le reazioni vitali deviate dal cancro".

Quindi non c'è una sostanza ma un metodo per la prevenzione e cura del cancro. L'alimentazione è una parte fondamentale per la prevenzione.
Un'alimentazione può essere sbagliata per vari motivi: eccesso o carenza d'introduzione di alimenti (errore quantitativo), un errore qualitativo che altera l'equilibrio nell'apporto di una percentuale di una singola classe di alimenti come ad esempio un eccesso di glucidi (zuccheri) o di lipidi (grassi) o un difetto di proteine.
Oltre alla qualità e quantità dei cibi va considerato il modo di cucinarli. Per essere sana e fisiologica la dieta deve essere equilibrata, mai eccessiva, assolutamente non ripetitiva ma varia, diversificata. Mangia secondo l'insegnamento del prof. Di Bella: "Un po' di tutto e di tutto un po'".

La neoplasia non è una malattia acuta, è una malattia cronica. La neoplasia (dal greco nèos, "nuovo" e plàsis, "formazione" poichè è una nuova crescita) non arriva per distruggerti ma per spingerti a trovare nuovi equilibri di vita perché quelli attuali non ti stanno facendo vivere ma morire lentamente nel cuore, anche se non te ne accorgi.
La malattia non è una punizione, è il risultato di uno stile di vita, di un modo di pensare, di un modo di essere e di affrontare gli eventi della vita.
Il segreto è diventare consapevoli che la chiave del cambiamento, dell'evoluzione, della salute, della felicità è osservare continuamente e dolcemente come ci parliamo e cosa immaginiamo dentro di noi rispetto alle cose che viviamo e trasformarlo sempre in modo più luminoso e pacifico.



Un caro saluto. Raffaele Ciruolo

          

Les fondations d'argile de la Commission von der Leyen

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La Commission présidée par la chrétienne-démocrate allemande Ursula von der Leyen va enfin entrer en fonction dimanche : par 461 voix contre 157 et 89 abstentions (707 présents sur 748 eurodéputés), soit 61% des voix, le Parlement européen a largement investi, mercredi à Strasbourg, le nouveau collège de 27 commissaires qui dirigera l’Union au cours des cinq prochaines années. Mais ce score est en trompe-l’œil : en réalité, jamais une commission n’a disposé d’une base politique aussi fragile et incertaine. Ce qui risque de compromettre son grand dessein, le «Green Deal» censé changer le modèle de développement européen.

Crises

Certes, par rapport à son vote d’investiture de juillet, la présidente de la Commission a sérieusement accru sa marge par rapport à la majorité absolue de 374 voix, un seuil nécessaire pour adopter les textes législatifs en seconde lecture : elle passe de 9 à 87 voix, ce qui lui offre a priori un seuil de sécurité appréciable. Mieux, l’ex-ministre de la Défense allemande a même réussi l’exploit de réunir une majorité plus large que celle obtenue par son prédécesseur, Jean-Claude Juncker, en octobre 2014 (423 voix contre 209 et 67 abstentions), qui était pourtant le candidat choisi par le Parlement à la différence d’Ursula von der Leyen, imposée par le Conseil européen des chefs d’Etat et de gouvernement. «Si le vote avait eu lieu à bulletins secrets, on aurait soupçonné une substitution d’urnes», s’amuse une éminence du PPE, le groupe conservateur, surprise par ce résultat inattendu.

La majorité qui l’a soutenue est constituée, sans surprise, des conservateurs du PPE (Parti populaire européen), le premier groupe politique qui a voté comme un seul homme pour elle, des socialistes (à l’exception d’une voix contre et de 9 abstentions, dont les Français) et de Renew Europe (RE), le groupe où siègent les élus macronistes (4 abstentions malgré tout). Elle a pu aussi compter sur le soutien de 30 eurodéputés eurosceptiques de l’ECR, en particulier ceux du PiS polonais, de 5 Verts et d’une partie du Mouvement Cinq Etoiles italien. Une autre partie de l’ECR a voté contre elle, avec l’ensemble de l’extrême droite, des europhobes britanniques de Nigel Farage, de la gauche radicale (dont LFI) et de 9 Verts. Enfin, la grande majorité des écologistes s’est réfugiée dans «l’abstention constructive», comme l’a expliqué Ska Keller, la coprésidente du groupe. Il est à noter que les deux groupes qui ont explosé façon puzzle sont les eurosceptiques de l’ECR et, dans une moindre mesure, les écologistes.

Le problème est que cette base politique n’est que de circonstance, car elle n’est liée par aucun programme politique, la négociation d’une «feuille de route» entre le PPE, les socialistes, RE et les Verts ayant été interrompue en juillet à la suite du rejet de la candidature de Manfred Weber, la tête de liste (allemande) du PPE, par le Conseil européen des chefs d’Etat et de gouvernement. Si Ursula von der Leyen a obtenu sa majorité, c’est essentiellement pour deux raisons : d’une part la volonté des eurodéputés de ne pas ajouter une crise européenne aux multiples crises politiques qui paralysent une partie des Etats membres (Royaume-Uni, bien sûr, mais aussi Espagne, Italie, Allemagne ou même France). Surtout, les logiques nationales ont corrigé les préventions idéologiques : chacun a voulu confirmer le commissaire de sa nationalité, comme le confiait sans illusion un membre du nouveau collège… Certes, Ursula von der Leyen a fait mieux que Juncker, mais beaucoup moins bien que tous les autres président de la Commission depuis que le Parlement a le pouvoir de les investir.

Tensions

L’hémicycle était d’ailleurs loin d’être plein lors du discours d’investiture de Von der Leyen, jugé par beaucoup de députés «ennuyeux» et «sans inspiration». «On sent de la frustration», juge Raphaël Glücksmann (Place publique), l’indifférence polie manifestée par les députés donnant «le sentiment d’une grande abstention, plus que d’une grande mobilisation». Stéphane Séjourné, le patron de la délégation française de RE, conscient de la démobilisation des eurodéputés, a d’ailleurs passé la session à mobiliser les énergies et à essayer de convaincre les écologistes de revenir sur leur consigne d’abstention. En vain. Or, sans cet apport essentiel, Von der Leyen restera une présidente faible, car sans majorité solide, contrairement à ses prédécesseurs, qui pouvaient compter sur le soutien indéfectible de la grande coalition conservateurs-socialistes. Ainsi, lorsqu’elle présentera ses textes sur le Green Deal, il est quasi-certain que les tensions nationales, surtout entre l’Est et l’Ouest, réapparaîtront, notamment au PPE et du groupe socialiste, des défections que devront être compensées par les Verts qui monnaieront leur vote au prix fort au risque d’accroître les divisions au sein des groupes politiques.


          

Organic Restaurants – NEBRASKA…

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Dazy Maze 521 South 13th St Omaha, NE 68102 402-346-9342 All vegetarian; organic and natural ingredients Dining by Design 6941 Forest Lake Blvd Lincoln, NE 68516 402-327-8880 Mostly organic produce, juice bar www.diningbydesign.com McFoster’s Natural Kind Cafe 302 S 38th St Omaha, NE 68131 402-345-7477 Vegan/macrobiotic friendly, some organic ingredients www.mcfosters.com Open Harvest 1618 South […]

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Organic Restaurants – LOUISIANA…

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Cafe Sunshine 2326 Line Ave Shreveport, LA 71104 318-227-2044 Vegetarian/macrobiotic meals Earthereal Restaurant 3309 Line Ave Shreveport, LA 71104 318-865-8947 Natural/macrobiotic foods Healthy Planet 678 Egan St Shreveport, LA 71101 318-425-0706 Vegan, organic Lulus in the Garden 1015 Washington Ave Apt D New Orleans, LA 70130 504-586-9956 Have 12 acre organic farm Back to the […]

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La doble vessant del dany per radiació: de les estratègies per a reduir-lo al seu ús en l’estudi de l’Aldosa Reductasa en condicions d’estrès oxidatiu.

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En aquest treball el terme dany per radiació, aplicat a sistemes biològics macromoleculars, fa referència a totes les modificacions, tant estructurals com químiques, induïdes pels raigs X en interaccionar amb la mostra experimental. En aquesta Tesi s’ha estudiat el dany per radiació en diferents sistemes biològics macromoleculars en dues vessants oposades. Per una banda, s’han caracteritzat diversos compostos scavenger nous, que poden ser útils per reduir els efectes del dany per radiació en experiments de cristal·lografia de proteïnes i dispersió de raigs X a angles baixos. Per altra banda, els mateixos efectes provocats pel dany per radicació s’han fet servir per a simular, de manera controlada, condicions d’estrès oxidatiu. Els resultats obtinguts en aquesta Tesi s’han distribuït en quatre capítols diferents. En el Capítol 1 es caracteritza la uridina com a compost scavenger en experiments de cristal·lografia de macromolècules a temperatura ambient. El poder mitigador de la uridina contra el dany per radiació en aquesta tècnica assenyala la potència d’aquest compost en els experiments de dispersió de raigs X a angles baixos publicats per Crosas et al. (2017). En el Capítol 2 s’estenen els resultats obtinguts a més nucleòsids i bases nitrogenades en experiments de dispersió de raigs X a angles baixos: 5-metil uridina, citidina, uridina i citosina. Aquests additius, que són els més potents reportats mai en la literatura, permeten mitigar el dany per radiació de manera molt significativa, millorar la qualitat de les dades i la informació continguda en solucions de proteïnes poc concentrades o amb baixos pesos moleculars, fet que estén el rang d’aplicació de la tècnica de SAXS. El Capítol 3 presenta els estudis de dany per radiació fets en cristalls de lisozim crescuts en presència de l’hidrogel peptídic Fmoc-CF, que es mostra com un compost scavenger efectiu contra el dany per radiació en experiments de cristal·lografia de proteïnes a temperatura ambient. A més, es proposa un nou mètode d’escalat de dades que permet corregir l’error sistemàtic provocat pel dany per radiació global a temperatura ambient. Per últim, en el Capítol 4, es presenten els resultats obtinguts en irradiar l’enzim Aldosa Reductasa, d’interès biomèdic en diabetis. Aquests resultats, publicats a Castellví et al. (2019), permeten aclarir quins són els canvis estructurals de la forma activada de la proteïna respecte de la nativa, i aclareixen perquè molts dels inhibidors farmacològics d’aquest enzim perden potència en tests in vivo. ; The term radiation damage in this work is applied to biological macromolecular systems and is defined as the structural and chemical modifications induced by X-rays when interacting with the sample under study. This PhD Thesis approaches the effects of the radiation damage in biological macromolecules in two very different ways. In one side, several new scavenger compounds have been characterized to mitigate the radiation damage effects in macromolecular crystallography and small-angle x-ray scattering, which in turn may enlarge the scientific cases in which these techniques can be used. In the other side, the effects produced by the radiation damage are used to mimic oxidative stress conditions in protein solutions. The results obtained in this Thesis are distributed in four chapters. In chapter 1 nucleoside uridine is characterized as a scavenger compound in macromolecular crystallography experiments at room temperature. The scavenging effect of uridine against radiation damage in this technique is in line with the high scavenging power in small angle x-ray experiments reported by Crosas et al. (2017). In chapter 2 the results are extended to more nucleosides and nitrogenous bases in small angle x-ray experiments. These additives, 5-methyl uridine, cytidine, uridine and cytosine, have the highest scavenging power ever reported, improve significantly the quality of the data and the meaningful information obtained in SAXS experiments, allow extending the technique to low molecular weight protein and to highly diluted protein solutions. Chapter 3 characterizes and assesses the radiation scavenging properties of composite lysozyme crystals grown in the hydropeptidic Fmoc-CF gel in macromolecular crystallography experiments at room temperature. Moreover, we propose a new method to scale the crystallographic data which corrects the systematic error induced by global radiation damage at room temperature. Finally, chapter 4 studies the effect of irradiation on aldose reductase, an enzyme which has a biomedical interest in diabetes. The study, which is published in Castellví et al. (2019), identifies the structural changes of the activated form of the protein with respect to the native form, and clarifies the reason why many drugs targeting the protein had their potency decreased in in vivo tests.
          

EVROPA: Je Emmanuel Macron ruský agent?

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Během společné tiskovky s generálním tajemníkem NATO Stoltenbergem 28. listopadu porušil francouzský prezident hned několik tabu a zneklidnil i nás.
          

A new vaccine strategy to combat viral infections in European-farmed finfish /

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La indústria aqüícola és un sector en creixement dinàmic i una font d’aliment d’alta qualitat en un context de decreixement dels estocs d’espècies salvatges i de necessitat d’assolir una seguretat alimentaria global. Les malalties víriques són encara una gran amenaça per a la producció de peixos i manquen estratègies terapèutiques antivirals. Normalment, les vacunes disponibles al mercat són en format de virus inactivats i només es dirigeixen a unes poques espècies de peixos amb un alt valor comercial. D’altra banda el procés de producció i administració de vacunes és car ja que requereix una administració individualitzada per injecció. En aquest escenari el desenvolupament de noves vacunes, eficaces i pràctiques que siguin adequades per a la vacunació massiva és una prioritat per a la indústria. En aquesta tesi hem abordat el problema utilitzant nous biomaterials per buscar estratègies innovadores. Hem produït de forma nanostructurada proteïnes virals antigèniques com a cossos d’inclusió bacterians (CI), produïts en Escherichia coli. El principal atractiu dels CI com a vacunes per a l’aqüicultura, és que són barats, segurs i estables in vivo sense necessitat d’encapsulació, a diferència de les proteïnes recombinants solubles. Proporcionen un reservori de proteïnes biològicament actives que s'alliberen lentament. En aquesta tesi les hem produït de tres virus rellevants per l’aqüicultura europea: la soca emergent del virus de la necrosi nerviosa (VNNV, RGNNV/SJNNV) que afecta els peixos de conreu marins mediterranis i els virus de la necrosis pancreàtica viral (IPNV) i de la septicèmia hemorràgica viral (VHSV), els quals afecten a salmònids. Presentem una caracterització completa de la producció i la resposta immune a tres nanopartícules fetes de proteïnes virals antigèniques de cada un dels virus: la proteïna C del VNNV, la proteïna VP2 de la càpside del IPNV i un fragment de la glicoproteïna G del VHSV. Demostrem que les tres nanopartícules són internalitzades per les cèl·lules hepàtiques del peix zebra (ZFL) utilitzant citometria de flux i microscòpia confocal. Utilitzant qPCR, demostrem que les nanopartícules tenen propietats immunostimulants in vitro, evocant una resposta immunitària innata anti-viral tant en ZFL com en cultius primaris de macròfags de truita. També demostrem que el peix zebra pot internalitzar les nanopartícules a través de l’epiteli de l'intestí el que suposa una prova de concepte per l’administració oral de les vacunes. En cap cas es van observar efectes tòxics in vivo ni en els assajos de citotoxicitat in vitro. En dos models in vivo utilitzant llenguado senegalès (S. senegalensis) i truita irisada (O. mykiss), demostrem que les proteïnes virals nanoestructurades VNNV-CNP i VHSV-G-frg16NP, quan s'injecten per via intraperitoneal (i. p. ), poden generar anticossos antivirals específics que ens indiquen que hem induït protecció. A més, mostrem que les IgMs anti-VHSV que es produeixen en truita tenen capacitat neutralitzant i que, després d’una infecció amb el virus, la supervivència dels peixos vacunats és coherent amb la protecció observada. Amb el llenguado senegalès es van realitzar també estudis d’expressió gènica i es va comparar la resposta d’anticossos després d’una administració i. p. i una administració oral utilitzant un nou mètode d’intubació. Els nostres resultats mostren que la via oral pot generar anticossos anti-virals, però ha de ser optimitzada per evitar una resposta de tolerància. Concloem que aquest nou enfoc per produir vacunes per espècies de peixos d’interès comercial desenvolupat en el marc d’aquesta tesis doctoral, mostra resultats molt prometedors. ; The aquaculture industry is a sector of dynamic growth, providing a high quality food source in the context of diminishing wild fish stocks and the need for global food security. Viral diseases are a major threat to finfish production and therapeutics are still lacking. Typically, commercially available vaccines are in the format of inactivated virus and are targeted to only a few, high market value fish species. The production and delivery process is expensive, with individual administration via injection. In this scenario, developing new, effective, practical vaccines which could be suitable for mass vaccination is a priority in the industry. In this thesis we have drawn on recent work in biomaterials science to seek innovative strategies. We have nanostructured antigenic fish viral proteins as bacterial inclusion bodies (IBs), produced in Escherichia coli. The attractiveness of IBs as a vaccine design for aquaculture is that they are cheap, safe and stable in vivo without encapsulation, in contrast to soluble proteins. They provide a reservoir of biologically active protein which is slowly released. Here we target three viruses relevant in European finfish farming: The emergent reassortant strain of viral nervous necrosis virus (VNNV strain RGNNV/SJNNV) affecting Mediterranean marine farmed fish, and infectious pancreatic necrosis virus (IPNV) and viral haemorrhagic septicaemia virus (VHSV), both affecting salmonids. We present a comprehensive study of the production and immune response to three protein nanoparticle IBs made of antigenic proteins from each virus, VNNV coat protein C, IPNV capsid protein VP2 and a VHSV glycoprotein G fragment. We demonstrate the three nanoparticles are taken up by zebrafish liver cells (ZFL) using flow cytometry and confocal microscopy. Using qPCR, we show the nanoparticles have immunostimulant properties in vitro, evoking an anti-viral innate immune response in ZFL and primary trout macrophage cultures. We also demonstrate by oral gavage that zebrafish can take up the nanoparticles through the intestine as a proof of concept for oral delivery. No toxic effects were observed in vivo nor in an MTT cytotoxicity assay in vitro. In in vivo farmed fish models using Senegalese sole (S. senegalensis) and rainbow trout (O. mykiss), we report the nanostructured viral proteins VNNV-CNP and VHSV-G-frg16NP, when injected intraperitoneally (i. p. ), can raise specific, antiviral antibodies, as a surrogate of protection. Moreover, we show the anti-VHSV IgMs raised in trout are neutralizing, and upon infectious challenge with the virus, survival of vaccinated fish is consistent with protection. In Senegalese sole we also performed immune gene expression studies and compared the antibody response for i. p. and oral delivery using a novel oral intubation method. Our findings show the oral route can raise anti-viral antibodies but needs to be optimized to avoid a tolerance response. We conclude this new approach to develop practical vaccines for farmed fish holds promise.
          

Stimulation of Glioma-Associated Microglia/Macrophages effector phagocytic synapse towards tumor clearance in glioma /

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Glioblastoma (GBM) es el tumor más agresivo dentro de la clasificación de gliomas y actualmente no tiene cura. Dado que hasta el 30% de las células en GBM son microglia y macrófagos (GAMMs desde ahora, por sus siglas en ingles), decidimos estudiarlos para ayudar en el diseño de posibles futuras inmunoterapias. El primer gran descubrimiento de esta tesis es la presencia de GAMM en las pseudo-empalizadas (PPs, por sus siglas en inglés) in GBM humano. Estas estructuras se cree que pueden contribuir a la capacidad de invasión del tumor, por lo que el papel de los GAMM en este microambiente puede ser crucial. En concreto, describimos que los GAMMs viajan a través de las PPs hacia su foco necrótico, de forma inversa a las células tumorales. Además, los GAMMs parece que ganan persistencia celular, es decir que viajan de forma directa, bajo las condiciones hipóxicas de las PPs y se desplazan de manera haptotáctica, siendo las fibras GFAP+ su sustrato para avanzar. Al llegar al área necrótica, cambian su fenotipo y fagocitan material del tumor, incluyendo fragmentos GFAP+ y núcleos celulares. En segundo lugar, en cultivos celulares hemos inducido la translocación de NF-κB p65 para aumentar la facogitosis de células de glioma (C6) por parte de microglia primaria de rata. Además, por medio de líneas celulares inmortalizadas (BV-2 y GL261) hemos descrito una serie de supuestos pasos que pueden ser importantes en el proceso de fagocitosis, así como la distribución de determinados receptores (CD11b y CD16/32) durante estas etapas. Asimismo, describimos la distribución de Iba-1 en los procesos de interacción fagocítica en modelos animales de glioma. Por último, hemos probado dos estrategias de inmunoterapia en un modelo murino de GBM (ratones C57/BL6 inyectados con células GL261 intracranealmente), descubriendo que estas inmunoterapias tienen efectos distintos: mientras la neutralización de CD47 pareció no ser efectiva, neutralizar SIRP1α parece ser beneficiosa. Así, los animales del grupo denominado CD47 no mostraban un aumento de su supervivencia comparados con los ratones control, incluso mostraban pérdida de peso, indicador de que la terapia pueda producir efectos secundarios sistémicos. Por otro lado, el bloqueo de SIRP permitió el incremento del peso corporal de los animales durante el experimento, y, de hecho, disminuyó el número de células en el centro del tumor incrementando la capacidad fagocítica de los GAMMs en las zonas periféricas de invasión, sin interferir en su capacidad de infiltrar en el tumor. En conclusión, esta tesis contribuye a una mejor comprensión de la función de los GAMMs en GBM y su capacidad fagocítica intrínseca, posiblemente ayudando al desarrollo de nuevas herramientas terapéuticas para luchar contra este tumor. ; Glioblastoma (GBM) is the most aggressive form of glioma and currently has no cure. Given that around 30% of the cells within the tumor are microglia/macrophages (glioma- associated microglia/macrophages or GAMM from now on), we decided to study them in order to shed light in possible future immunotherapies. The first discovery during this investigation was the presence of GAMM in pseudopalisades (PPs) of human GBM. These structures are thought to be very important in the contribution of the tumor invasiveness, therefore the knowledge of the role of GAMMs here might be crucial. Particularly, GAMMs were found to be traveling through the PPs towards the necrotic focus, contrasting with the tumor cells. Moreover, the myeloid cells seem to gain cellular persistence with the hypoxic gradient and travel in a haptotactic manner using the gradient of glioma cells as a cue. When they reach the necrotic focus, they shift their phenotype and phagocytose tumor material, including GFAP+ fragments and nuclei. Secondly, by means of cell cultures we achieved to translocate p65 NF-κB and promote phagocytosis of tumor glioma cells (C6) by primary microglia. Moreover, using cell lines (BV-2 and GL261) we described the putative steps of phagocytosis and the distribution of some receptors (CD11b and CD16/32) involved in the process of phagocytosis. Importantly, the distribution of Iba-1 in interacting GAMMs was also defined in the animal models. Finally, we tested two immunotherapy strategies in a immunocompetent GBM animal model (C57/BL6 intracraneally inoculated with GL261 cells), and discovered that both immunotherapies have different outcomes: while CD47 neutralizing antibody seemed to be non-effective, neutralizing SIRP1α had a beneficial outcome. This way, anti-CD47 treated animals did not have any increase on survival rate than control groups; and they showed decreased bodyweight throughout the experiment, suggesting that the therapy had some systemic side effects. On the other hand, blocking SIRP1α allowed the increase of the bodyweight of the animals throughout the experiment, and decreased the cellularity of the tumor core by increasing the phagocytic activity of GAMM at the peripheral area of tumor invasion without interfering in their infiltration capacity. In all, this thesis contributes to a better understanding of the role of GAMMs in GBM and the intrinsic phagocytic capacity they can play, possibly helping in the development of immunotherapeutic tools to fight this fatal tumor.
          

New Arrival Stock 23 November 2019

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佳能公布多款RF卡口无反镜头专利

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近日,佳能在日本公布rf 16-35mm f4、rf 20mm f2、rf 35mm f1.8、rf 35mm f2、rf 35mm f2.8、rf 45mm f2.8镜头专利,专利编号为2019-204115。截至目前,佳能rf卡口系统仅拥有一款非l级别定焦镜头:rf 35mm f1.8 macro is stm。

佳能rf 16-35mm f4镜头专利详情:

  • 焦距:16.48 24.02 33.75mm
  • 光圈:4.12
  • 半画角:52.70 42.01 32.66
  • 像高:21.64mm
  • 镜头全长:117.64 109.16 110.13mm
  • 后焦距:11.50 19.17 29.63mm

佳能rf 20mm f2镜头专利详情:


继续阅读全文 佳能公布多款RF卡口无反镜头专利
          

Mes: spinge al default. Il Governo non ha mandato a firmare, riconosca la funzione del Parlamento

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FILE PHOTO: European Flags flutter outside the European Commission's headquarters ahead of the European Union leaders summit, in Brussels

Il Meccanismo europeo di stabilità (Mes) non è nel programma sul quale il Governo Conte ha avuto la fiducia di Camera e Senato. Il Pd eviti forzature. Sul Mes, il Parlamento italiano non “si è svegliato tardi”. Al contrario, il 19 Giugno scorso, ha impegnato in modo molto chiaro il governo a “render note alle Camere le proposte di modifica al trattato ESM, elaborate in sede europea, al fine di consentire al Parlamento di esprimersi con un atto di indirizzo e, conseguentemente, a sospendere ogni determinazione definitiva finché il Parlamento non si sia pronunciato.” Come noto, il Parlamento non è stato chiamato a pronunciarsi nel merito. Non vi può essere stata, quindi, nessuna determinazione definitiva, né può esservi il 13 Dicembre. Senza ulteriori drammatizzazioni, il governo riconosca che non ha avuto e non ha il mandato per firmare il Trattato. Si impegni per riaprire il negoziato, in stretto rapporto con gli altri due capitoli del “pacchetto”: l’Unione bancaria e lo strumento di bilancio per l’euro-zona. Poi, si metta il Parlamento nelle condizioni di fare un’approfondita valutazione complessiva.

Nella discussione del Mes, è autolesionistica la rappresentazione alimentata da parte dell’intellighenzia progressista e dal Pd come scontro tra europeisti responsabili, da una parte, e irresponsabili sovranisti o inaffidabili populasti dall’altra; tra chi vuole salvaguardare la continuità dell’Italia nella Ue e nell’eurozona e chi vuole rompere. Va, invece, valutato il testo del Trattato e il contesto politico e macroeconomico nel quale opererà, nel tentativo di stare nel gorgo europeo con un minimo di autonomia culturale e politica e attenzione alle fasce sociali più deboli.

In estrema sintesi, il testo, per Paesi in condizioni di finanza pubblica come l’Italia, elimina le possibilità di sostegno finanziario senza dover ristrutturare il debito pubblico, quindi determina un enorme rischio di default che si auto-avvera. La ristrutturazione del debito pubblico non è più un evento possibile, ma improbabile, estremo, da scongiurare con ogni mezzo (dal “whatever it takes”, all’Omt e relativo programma di aggiustamenti strutturali): diventa, invece, uno strumento ordinario, previsto e disciplinato con tanto di clausole (le single limb Cacs) per evitare anche a larghe maggioranze di risparmiatori al dettaglio di bloccare l’offerta di tagli al capitale investito.

Gli articoli più pericolosi sono il 13 e il 14, integrati dall’Annex III, del testo ridefinito: rispetto alla versione in vigore, l’Italia è esclusa anche formalmente dalla linea di credito precauzionale (Precautionary Conditioned Credit Line), ma è di fatto esclusa anche dalla seconda linea di credito (Enhanced Conditions Credit Line), poiché per l’attivazione di quest’ultima è previsto un debito sostenibile e la capacità di ripagamento dei prestiti, la cui valutazione è affidata esclusivamente al board del Mes.

Gli articoli 13 e 14 sono diretta conseguenza di alcuni punti della premessa: il punto 12), dove è scritto che “il Mes può facilitare il dialogo tra un Paese membro e i suoi creditori privati, su basi volontarie, informali, non vincolanti, temporanee e riservate”; il punto 12A) dove, come ricordato sopra, è affermata la responsabilità esclusiva del Mes stesso a valutare la capacità di un Paese di ripagare il prestito ricevuto (in altri termini, la Commissione europea ha l’ultima parola sulla sostenibilità del debito pubblico di chi è in difficoltà, ma è il Mes, in realtà, a decidere se il malcapitato può ricevere aiuto senza ristrutturare il suo debito pubblico); il punto 12B), dove è prevista “in casi eccezionali, un’adeguata e proporzionata forma di coinvolgimento del settore privato quando è concesso il supporto finanziario per la stabilità”. Insomma, come è stato efficacemente sottolineato da Vladimiro Giacchè, Presidente del CER, in audizione in Commissione Bilancio alla Camera, viene definito un quadro da “Comma 22”: si predispone un efficace meccanismo di sostegno finanziario per i Paesi in difficoltà di finanza pubblica per evitar la ristrutturazione del debito; ma se sei un Paese in difficoltà di finanza pubblica, non puoi accedere al meccanismo finanziario a causa delle condizionalità ex ante. Allora, qual è il senso di policy del revisionato Trattato: innalzare la funzione disciplinante dei mercati finanziari in aiuto alle normative del Fiscal Compact aggirate nella loro efficacia dalla cosiddette clausole di flessibilità.

Ma c’è il backstop per le banche in difficoltà, insistono dal Mef. Vero. Ma per l’Italia, è una “protezione” virtuale, a parte il fatto che, più che una generosa concessione a noi, è una potenziale garanzia alle banche tedesche già salvate una volta dai contribuenti nazionali ed europei prima dell’avvio del bail-in. Come ha descritto qualche giorno fa il noto bocconiano anti-europeista prof Alessandro Penati, il backstop scatterebbe soltanto dopo aver azzerato azionisti, obbligazionisti subordinati e senior e i depositi bancari per la porzione superiore ai 100.000 euro: in sostanza, dopo un cataclisma che per noi implicherebbe, comunque, inesorabilmente, la ristrutturazione del debito pubblico.

Oltre al testo, rileva il contesto. Il testo è un fiammifero acceso vicino a un lago di benzina: ossia, la prospettiva di stagnazione economica, l’innalzamento dei tassi di interesse e inflazione zero. È pessimismo esagerato? Purtroppo, no. Perché? Primo elemento di contesto: siamo prigionieri di un’agenda di cronica anemia di domanda aggregata, determinata dalla resistenza a invertire la rotta di politica economica di fronte agli impedimenti strutturali alle esportazioni. Il mercantilismo praticato da un quarto di secolo in forma estrema dalla Ue e dall’eurozona determina, inevitabilmente, i dazi del Presidente Trump. Sarebbe necessaria e urgente una svolta keynesiana per alimentare la domanda interna attraverso investimenti pubblici per la riconversione ecologica dell’economia, ma la neo-Presidente della Commissione europea ha ribadito, subito dopo la “fiducia” data dal Parlamento di Strasburgo alla sua Commissione, il no senza se e senza ma all’esclusione dal calcolo del deficit della spesa green in conto capitale.

Secondo elemento di contesto: le pressioni tedesche e della cosiddetta “Lega anseatica” per invertire il segno della politica monetaria della Bce. La scorsa settimana, Moody’s ha rivisto da stabili a negative le valutazioni prospettiche per le banche tedesche in relazione alla loro scarsa redditività causata, in primo luogo, dai previsti tassi di interesse negativi. Insomma, il dopo Draghi, nonostante la resistenza di Ms Lagarde, va verso la fine del Quantitative easing e il ripristino della “normalità”.

Terzo elemento di contesto, la restrizione, più o meno accentuata, delle possibilità acquisto di titoli sovrani da parte delle banche, condizione posta da Berlino per il completamento dell’Unione bancaria. Qui, siamo di fronte al concreto esempio della definizione di stupidità di Carlo Maria Cipolla: una siffatta Unione bancaria sarebbe meglio perderla che trovarla, perché determinerebbe non soltanto un innalzamento dei tassi di interesse su titoli di debito pubblico, in particolare per noi, ma aumenti di capitale per l’intero mondo bancario, incluse le malmesse banche tedesche.

In conclusione, è vero quanto sostiene il Ministro Gualtieri: aspetti negativi erano inclusi anche nella versione del Mes ancora in vigore. È vero anche che, le proposte iniziali di Germania e Paesi nordici erano ancora più pericolose in quanto prevedevano ufficialmente un’automatismo per la ristrutturazione del debito. Ma sono argomenti deboli. “Poteva andare peggio, accontentiamoci”, è un principio-guida perdente e deleterio per l’interesse nazionale, come hanno dovuto riconoscere, ex-post, per il bail-in tanti sedicenti europeisti responsabili. Nella fase storica in corso e alla luce degli evidenti fallimenti dell’agenda mercantilista europea, sia sul versante dell’economia reale che di finanza pubblica, sarebbe necessaria un’inversione di rotta. O, almeno, non peggiorare il terreno di gioco. Invece, il Trattato revisionato conferma e aggrava un impianto insostenibile per l’Italia, ma anche per i paesi core, a partire dalle banche della virtuosa Germania.


          

Solo con l'economia circolare si può fare una politica industriale innovativa e inclusiva

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Economia circolare, innovazione sociale, occupazione: questo è il circuito virtuoso, tra economia della conoscenza e sviluppo territoriale partecipato (Community-led Local Development), verso cui la Cgil ha, da diverso tempo, impegnato tutte le sue strutture.

Abbiamo iniziato a occuparci di economia circolare ben ventidue anni fa. Era il 23 aprile 1999 e nella Sala Santi avevamo invitato i principali centri di ricerca tra cui il Fraunhofer-Institut für Systemtechnik und Innovationsforschung (ISI) di Karlsruhe e gli studiosi che si occupavano di ciò che allora definivamo “economia dei cicli chiusi”. La chiusura dei cicli produttivi, di energia e dei rifiuti, fin da allora, la consideravamo strumento e strategia verso la coesione sociale e territoriale, la qualità della vita e del lavoro in Italia e in Europa.

Nel corso di quella conferenza internazionale, ci ponevamo le seguenti domande, a cui ancora oggi stiamo cercando di dare risposta attraverso tutta la nostra attività negoziale, sia a livello nazionale che decentrato: è possibile coniugare la competitività e l’occupazione con la necessità di far fronte alle sfide ambientali? Quale modello di sviluppo adottare da opporre a quello di mera crescita economica? Quali sono le condizioni che permettono l’implementazione di questi modelli e di questi processi? Quali sono le implicazioni? Quali sistemi regolativi adottare a sfondo di questi processi?

Fin da allora, mettevamo in discussione i tradizionali modelli di crescita economica basati su processi di produzione lineari, dissipativi di risorse materiali e immateriali, ragionando sulla necessità di nuovi modelli di sviluppo basati sulla chiusura dei cicli dei materiali e delle risorse. Nell’economia circolare, quindi, identificavamo i principi per ridefinire la crescita e, quindi, un nuovo modello di sviluppo che implicasse il graduale disaccoppiamento dell’attività economica dal consumo di risorse non-rinnovabili e dalla produzione di rifiuti favorendo una transizione verso fonti di energia rinnovabile e la valorizzazione e rigenerazione del capitale economico, naturale e sociale.

Passare da modelli produttivi basati sulla “produzione-consumo-eliminazione” rapida e lineare dei beni, a delle strategie tecno-economiche fondate su cicli di “riutilizzo-riparazione-ripristino” dei prodotti e delle risorse, significava, per noi, passare da innovazioni di “bassa via” - che fanno leva principalmente sui costi di produzione, tra cui il lavoro - a un’“alta” via dell’innovazione che facesse perno sulla qualità dei prodotti e dei processi.

La sfida era notevole: strategie di politica industriale volte all’economia circolare implicano orientare gli attori socio-economici a ridefinire le regole dell’organizzazione del lavoro, del sistema tecnologico e della produzione, dei rapporti a monte e a valle l’impresa e tra le aziende delle diverse filiere industriali.

È passato molto tempo da allora, e la crisi economica e sociale prodotta dai cambiamenti climatico, richiede da parte dei governi - e di corpi intermedi come il sindacato - analisi lucide e una decisa assunzione di responsabilità di fronte a una situazione mondiale sempre più complessa.

Durante anni in cui la discussione di politica economica e monetaria si è polarizzata sulle alternative tra Stato (dirigismo) e Mercato (concorrenza), avvertiamo la necessità di passare da una logica industriale dell’efficienza, del dirigismo e della competitività sfrenata, a una logica post-industriale volta ai benefici per gli utilizzatori, all’innovazione economica e sociale e a un cambiamento strutturale e istituzionale che faccia perno sulla collaborazione interistituzionale e la partecipazione sociale.

In questa prospettiva, intendiamo l’innovazione come cambiamento strutturale e come processo di apprendimento interattivo o collettivo, all’interno delle imprese, nei cluster territoriali, nelle reti/filiere produttive e, in generale, a livello sociale/istituzionale per creare nuove produzioni in una cornice strategica di “alta via all’innovazione”.

L’economia circolare si inquadra quindi, per noi, in una più generale strategia di politica economica orientata ai cittadini, al territorio, alle persone. Al modello della politica Ue centrata sulla politica monetaria e dei bilanci pubblici, riteniamo indispensabile, su scala europea e nazionale, far leva su un terzo strumento di politica economica che è la politica “industriale”.

Nel tempo, le strategie e gli strumenti della politica industriale sono mutati al variare delle diverse fasi di sviluppo (fordismo, specializzazione flessibile, coproduzione, co-creazione) e degli approcci di tipo politico (dirigismo o competizione). La strategia di politica industriale che, per noi, può far da cornice allo sviluppo dell’economia circolare nei nostri territori fa contestualmente leva sulle reti di centri di competenza, sui milieu locali di innovazione, sulle smart specializations, sull’infrastrutturazione smart delle nostre filiere produttive.

Da Nord a Sud d’Italia, possiamo contare su svariati esempi, in cui le nostre strutture confederali tra modelli di produzione lineare di beni e servizi hanno sostenuto l’importanza di quella circolare: a La Spezia e a Livorno, ad esempio, le Camere del Lavoro locali hanno sostenuto la realizzazione di un biodigestore anaerobico volto a migliorare il recupero di risorse dai rifiuti, fino ad arrivare da ultimo alla distribuzione (gratis, o a tariffe molto agevolate a seconda dei casi) dell’energia prodotta dal recupero del biogas ai cittadini e alle imprese locali.

A Ravenna abbiamo proposto, alla discussione pubblica, la realizzazione di un impianto di captazione nell’area industriale del petrolchimico di Ravenna per “catturare” l’anidride carbonica prodotta dai siti industriali. Così come, a livello nazionale, nell’audizione parlamentare sul decreto cosiddetto “Crescita” (Decreto-legge n. 34 del 30 aprile 2019 - Misure urgenti di crescita economica e per la risoluzione di specifiche situazioni di crisi) il 9 maggio 2019, abbiamo presentato una Piattaforma unitaria in cui esprimevamo l’esigenza di prevedere maggiori investimenti pubblici e una nuova politica industriale che sostenesse la domanda interna e non l’offerta, orientata al sostegno delle nuove filiere strategiche – soprattutto legate alla green economy, all’economia circolare e allo sviluppo sostenibile – per incrementare anche gli investimenti privati, le competenze e le professionalità, l’occupazione e i salari.

Qui, tuttavia, vorrei inquadrare queste iniziative in una cornice più generale: quella della negozialità della politica industriale e dell’innovazione a livello territoriale. Come noto, l’obiettivo generale delle politiche industriali è quello di orientare l’economia verso direzioni “condivise” dal punto di vista economico (favorendone l’efficienza), sociale (dando risposta a bisogni sociali incoraggiando eguaglianza equità e inclusione), ambientale (assicurando la sostenibilità), politico (proteggendo particolari interessi nazionali) di contesto (istruzione, conoscenze, infrastrutture, materie prime, indispensabili per lo sviluppo di nuovi settori.

Posto che tali obiettivi non possano essere raggiunti dai comportamenti privati degli operatori sui mercati e, soprattutto perché la loro complessità implica la possibilità che essi siano in conflitto tra loro, le politiche industriali presuppongono una condivisione multiattoriale tra Stato, Mercato e Società dello sviluppo socio-territoriale e richiedono la presenza di istituzioni che abbiano le competenze e gli strumenti per realizzarle.

Mai come oggi, gli orientamenti e l’implementazione delle politiche industriali sono caratterizzate da alti livelli di complessità e capziosità, in quanto coinvolgono diversi attori sociali e comunità con valori, interessi, significati e prospettive spesso divergenti. La loro caratterizzazione value-driven mette quindi in discussione l’applicazione dei tradizionali approcci problem solving che, ai vari livelli istituzionali, dal macro al micro, tendono alla centralità delle decisioni.

Quando, come Cgil, parliamo di politiche industriali volte ai cittadini, ai territori e alle persone, facendo perno sulla collaborazione interistituzionale e sulla partecipazione sociale, ci riferiamo a un modello di governance multilivello della politica industriale che promuova un’economia inclusiva e circolare a partire dai nostri territori. Il nostro modello di intervento è dunque implementabile a partire dalla negozialità territoriale dell’innovazione.

Soprattutto negli ultimi 35 anni, il modello di sviluppo mainstream conta su modalità di accumulazione estrattive e tarate sul breve periodo. Le sue principali leve - liberalizzazione dei mercati di beni e servizi e dei mercati finanziari, la liberalizzazione del mercato del lavoro, i processi di privatizzazione – hanno acuito la disconnessione dell’azione economica dalle esigenze della riproduzione sociale: innanzitutto dal lavoro, strumento identitario ma anche medium fondamentale della distribuzione del reddito e della cittadinanza sociale; dai tempi lunghi della riproduzione sociale, a beneficio di dinamiche di massimizzazione del rendimento del capitale nel breve periodo; una disconnessione, infine, dallo spazio (dai luoghi, dai territori) della riproduzione sociale, rincorrendo la continua ricomposizione delle catene del valore su scala globale al fine del dumping sociale (riduzione dei costi del lavoro e di elusione dei vincoli regolativi nazionali e regionali).

In Italia, ad esempio, in un contesto cioè tradizionalmente connotato dalla diffusione della piccola e media impresa, la regolazione dei processi è definita in ragione di esigenze di accumulazione “estrattiva” e finance-based, poste dalle imprese-guida a fornitori e sub-fornitori attraverso dinamiche di estrazione di valore sul piano della regolazione e dell’organizzazione del lavoro.

Sotto questo profilo, soprattutto a partire dagli anni Novanta, la riorganizzazione delle catene di valore globale ha prodotto posizioni di comodo nel trattamento del lavoro: i processi di disintegrazione verticale sono infatti avvenuti frammentando i processi di produzione in una miriade di soggettività giuridiche diverse attraverso forme di elusione istituzionale con la quale i datori di lavoro potessero estrarre valore aggiunto aggirando vincoli e sottraendosi alle proprie responsabilità.

Questa transizione neo-liberista, breve-periodista e di natura “estrattiva”, offre un contesto che sta potenzialmente dequalificando le persone a praticare scambi simmetrici win win in cui le parti che collaborano, possano - tutte - trarne vantaggio. Nella misura in cui la disuguaglianza materiale isola le persone, la frammentazione del lavoro rende più superficiali i contatti con l’altro, l’insicurezza sociale e la complessità della crisi climatica ed economica sta innescando l’angoscia per il cambiamento e, in generale, le differenze tra le persone sono ridotte e omologate al pensiero unico del profitto e della profittabilità.

A questo modello “estrattivo” di risorse, consci delle sfide economiche e sociali derivanti dalla crisi climatica e ambientale globale, a livello territoriale, dalla più piccola Camera del Lavoro del sud d’Italia alla Camera del Lavoro Metropolitana di Milano, la Cgil sta opponendo un modello di politica industriale inclusivo e circolare attraverso processi di negozialità “generativa e capacitante”: attraverso alleanze strategiche, specie con università e centri di ricerca, attraverso la contrattazione formale e informale, iniziative e progetti, stiamo avviando sul territorio procedure e pratiche in cui negoziamo e condividiamo, in primis, una visione di futuro.

Nei territori in cui il nostro Sindacato sta sostenendo strumenti e pratiche di economia circolare e di innovazione sociale, sono stati, innanzitutto, attivati processi e progetti che stanno “riconoscendo”, connettendo e gradualmente portando “a sintesi” innanzitutto i valori e gli interessi in gioco diversamente attribuiti dagli attori sociali alle risorse e alle vocazioni del proprio territorio.

In questa cornice, le nuove tecnologie digitali diventano “abilitanti” di nuove relazioni territoriali e di empowerment sociale, specie laddove il sindacato riesce a ripensarsi e a riconoscersi il nuovo ruolo che è chiamato a svolgere per far fronte alle sfide socioeconomiche.

In materia di politica industriale e di innovazione, in molti territori, il ruolo che giochiamo travalica il perimetro tradizionale sindacale di rappresentanza e rappresentatività: l’uso intelligente e generativo delle reti digitali, infatti, sta creando nuovi spazi di azione negoziale confederale, in cui stanno prendendo forma relazioni sociali multiattoriali di condivisione delle risorse, delle conoscenze e dei problemi da affrontare per creare (e propagare) significati, progetti e percorsi condivisi.

Nel modello di relazioni industriali di rappresentazione diffusa degli interessi a livello territoriale, l’utilizzo sindacale delle nuove tecnologie digitali, in molti casi, allarga la rete di relazioni della confederalità territoriale aprendola anche a nuovi attori, a nuove figure di rappresentati a livello urbano e a una nuova rappresentanza di bisogni, configurando modalità comunicative partecipate, con lo scopo di condividere, e poi, di assumere di volta in volta, decisioni e strategie, creando nuovi spazi di interlocuzione, di condivisione e di progettualità con gli altri stakeholders locali.  

Laddove si stanno restringendo gli spazi di governance locale delle politiche del lavoro e dello sviluppo, queste iniziative sembrano sostituire con efficacia i tradizionali strumenti dei contratti d’area e i patti territoriali di una stagione concertativa ormai al tramonto.

Ormai da decenni può dirsi conclusa la fase propulsiva del fordismo, capace di combinare alta occupazione e crescita del Prodotto Interno Lordo dei nostri Paesi grazie all’aumento della produzione e degli investimenti mirati solo su l’offerta e perseguita ad alti costi ambientali. Così come è cresciuta la percezione sociale degli effetti di questa crescita sfrenata, che ha portato al superamento dei limiti invalicabili delle risorse del nostro pianeta e alla perdita di diversità biologica, della stabilità climatica di cui non si possono più negare gli effetti retroattivi sui sistemi economici e sociali a tutte le latitudini del globo.

Un modello di politica industriale volto ai cittadini, ai territori e alle persone richiede, dunque, da parte di un corpo intermedio come il Sindacato, di perseguire l’innovazione socio-territoriale uscendo dai tradizionali spazi di rappresentanza e rappresentatività sindacale che facevano perno strettamente sulla fabbrica infra muros e sui settori produttivi.

Si tratta, da parte nostra, di aprirsi a tutta la filiera dei diritti di cittadinanza e del lavoro negoziando circuiti virtuosi di economia circolare, innovazione sociale e occupazione affinché le capacità immaginative e progettuali dei nostri territori, verso un futuro inclusivo e solidale, possano esprimere il loro potenziale.


          

Erdogan török elnök reagál Macron kijelentéseire

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Macron francia elnök az agyhalál megnevezéssel sokkolta a NATO partnereit. A reakciók széles skálán mozognak “átgondolt” és “aggódó” reakciók között. Erdogan török elnök most új aspektusokat ad hozzá, és reagál Macron kijelentésére. A francia államfő, Emmanuel Macron Törökország szíriai támadásának kritikája után, Recep Tayyip Erdogan török elnök kollégáját “agyhalottnak” nevezte. “Először ellenőrizzük a saját agyad […]
          

Mitakon Creator 85mm f/2.8 1-5X Super Macro Lens Announced

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ZyOptics has announced the Mitakon Creator 85mm f/2.8 1-5X Super Macro lens for various mounts including Canon EF, Nikon F,…

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New and altered geographic names of Te Tau ihu

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On 1 August 2014 a number of new or altered geographic names took effect as a result of the following Treaty Claims settlements:

More information about, and exact location of, these places can be found on Land Information New Zealand's Gazeteer or the GIS maps produced by Nelson City Council, Tasman District and Marlborough District Councils. History, orgin and meaning information about the names has been taken from the LINZ Gazeteer. More complete information about the cultural associations iwi have with places and resources throughout the top of the south can be found in the Te Tau Ihu Statutory Acknowledgements, 2014 [PDF] (Nelson City Council, Tasman District Council, Marlborough District Council).  A statutory acknowledgement recognises the particular cultural, spiritual, historical and traditional association of an iwi with an identified site/area and is one form of redress [PDF] required by the Te Tau Ihu Settlement Act(s).

Nelson/ Tasman/ Marlborough Sounds/ Marlborough
Nelson (see also Tohu Whenua - Sites of Significance)
  • Pikimai/ Church Hill
    Church Hill, Nelson Cathedral. A Ngāti Kōata pa site. Was also locally known as Church Hill.
    pikimaiAC449.jpgMabel Annesley, after Barnicoat, John Wallis (1814-1905). Early State of Church Hill, 1842. Pencil drawing on paper, with watercolour wash. The Nelson Provincial Museum, Bett Collection: AC449.
    Click image to enlarge
  • Horoirangi / Drumduan
    A hill at 657 m east of Glenduan approximately 14 km northeast of Nelson City. Ngāti Kōata states that this is the highest peak at back of Glenduan and refers to the ascending from the heavens, and has cultural associations for Ngāti Kōata. Ngāti Kuia: Peart, in Old Tasman Bay (p. 125) translates Horoirangi as ‘Washing of the sky.” This is the highest peak at the back of the Glenduan. Its name derives from the description of when the clouds envelope Horo-i-rangi, which is a sign of bad weather.
  • Rotokura / Cable Bay
    A bay adjacent to Pepin Island between Ataata Point and Fall Cove approximately 16 km northeast of Nelson City. Te Atiawa and Ngāti Tama note that there is an old pā site at the Pepin Island end of the causeway and Rotokura was named as it provided ethereal reflections of the tall native trees, great solitude and peace of mind.
  • Tasman Bay / Te Tai-o-Aorere
    Ngāti Tama and Te Atiawa state that; this is the name the Bay was known by our tipuna; this name is recorded in historical evidence for the Tribunal; sometimes Te Tai-o-Aorere is called Te Tai Tapu which is a mistake as Te Tai Tapu is Golden Bay;Te Tai-o-Aorere is the ancient name for Tasman Bay and Manawhenua iwi continue to use the name today Ngāti Kuia history: Ko Maungatapu te maunga Ko Mahitahi te Awa Ko Te Tai-Aorere te Moana Ko Whakatu te Marae Ko Ngāti Kuia te Iwi Ngāti Kuia have lived on the shores of Te Tai-o-Aorere and it forms part of our pepeha and identity.
  • Te Punawai Pā
    South east of Haulashore Island. Old Ngāti Koata pa site on hill side and down to beach to left of Richardson Street (i.e. towards the Port).
Tasman
  • Golden Bay/ Mohua
  • Wharepapa / Arthur Range
    Ngāti Tama notes that Wharepapa is a sacred ancestor, providing a historical and spiritual link to the natural world. Wharepapa is the highest maunga in the takiwa and a vital link to the spirits. Ngātii Rarua history: the highest peak of these ranges is Tu Ao Wharepapa and is one of the two sacred maunga for the manawhenua of Motueka. Its significance is embodied in the pepeha “Ko Tu Ao Wharepapa te maunga, ko Ngāti Rarua te iwi….”. Important source of the plant Nei Nei which was used to manufacture the wet weather capes worn by our tupuna. Also a number of sacred caves or tomo are situated within this maunga.
  • Pourangahau / Mount Robert
    A hill at 1421 m adjacent to Lake Rotoiti on Robert Ridge approximately 4.5 km southwest of St Arnaud. Ngāti Apa Tribunal evidence says that Pourangahau translates as a standing place for the “posts of research”. From here, Ngāti Apa were able to look over the sacred lake of Rotoiti.
  • Mangatāwhai
    Intersection of Tophouse/ Korere Tophouse Road. Ngāti Kuia Tribunal evidence states that Mangatawhai translates as ‘place of many trails’. This area was where many of the trails connecting Nelson, Marlborough, West Coast and Canterbury connected.
    Mountarthurtdc.jpgMount Arthur from Tapawera. Tasman District Council
    Click image to enlarge
  • Paratītahi Tarns
    Between Mt McRae and Peanter Peak, SE Lake Rotoiti. Ngāti Apa Tribunal evidence states that the proposed names mean ‘Purpose in life’. Ariki children were taken here in summer time to be washed, before presentation to the people in life.
  • Pikikirunga/ Canaan Downs
    Off Takaka Hill. Te Atiawa and Ngāti Tama state that Pikikirunga is named after a taniwha and the traditions of karanga. Wainui Caves say Ngararahuarau gave the first karanga and when he died he exploded and his scales were embedded in the hills. Was locally known as Canaan Downs.
  • Pukekoikoi Hill                
    Nr Tapu Bay, SW of Kaiteriteri. Te Atiawa and Ngāti Tama state that: this is a significant area for Te Atiawa. The tipuna called the hill by this name (it is recorded in J.D. Peart, 1937, Old Tasman Bay, p. 128). Pukekoikoi was renowned for its use of koikoi as more practical rākau to use when learning the blocks, the attack and the defensive movements of mau rākau.
  • Te Araruahinewai
    Confluence of Maitland Creek/ Motueka River. Headwaters of the Motueka, which is called – Te Ara Ruahinewai - meaning "Lead us from the hinterland to Tasman Bay" – where the marriages between the hapu were consecrated to enable safe travel.
  • Hinemoatū / Howard River
    A river flowing from the confluence of Hodgson Stream and Tier Stream into the Buller River, approximately 13 km west-northwest of Lake Rotoiti. Ngāti Apa Tribunal evidence describes Hinemoatū as a Ngāti Apa ancestress; mother of Tama, a great mokopuna of Tarakaipa.
  • Maniniaro / Angelus Peak
    A hill at 2075m at the western end of Angelus Ridge in Travers Range approximately 7.5km southwest of Lake Rotoiti. Ngāti Apa Tribunal evidence states that this is the accompanying lake to Roto Maninitua – both are the footpaths of Ngāti Apa’s dead, as they fly back to touch the shores of Hawaikinui, Hawaiki.
  • Maungakura / Red Hill
    A hill at 1791 m on Red Hills Ridge near the upper reaches of Motueka River Right Branch approximately 26 km northeast of St Arnaud. Ngāti Apa Tribunal evidence states that Te Huarau was a taniwha, a kaitiaki, and he and she kept the Maungakura safe from harm.
  • Motuareronui / Adele Island
    An island north of Fisherman Island separated from Te Waipounamu by Astrolabe Roadstead, approximately 5 km northeast of Marahau. Ngāti Tama and Te Atiawa state that whanau korero says that Motuareronui is the big island of the swift moving clouds. Ngāti Rarua describes this as a large tongue shaped island.
  • Poukirikiri / Travers Saddle
    A saddle approximately 1.5 km south of Mount Travers in St Arnaud Range, between East Branch Sabine River and the upper end of Travers River, approximately 19km southwest of Lake Rotoiti. Ngāti Apa Tribunal evidence states that this is the pathway to our sacred mountain of Kehu (Kehu Peak) – a guide to our elders and protector of the last swimming place of our spirits before they return to Hawaiki.
  • Pukeone / Mount Campbell
    A hill at 1330 m east of Wharepapa / Arthur Range between Riuwaka River South Branch and Pokororo River approximately 13 km west of Motueka. Te Atiawa notes that Pukeone (meaning sandy hill) is where Te Atiawa carried the sand to the top of the hill to signal to whanau. The brown area today marks where the fires used to be. Pukeone is highly significant to Te Atiawa. Ngāti Rarua history: there is korero regarding the origins of the name Pukeone and one theory advances that it is a tupuna name from early times perhaps belonging to one of Rakaihautu’s party. The translation of Sand Hill however can be related to the practice of carrying sand to the summit of the maunga where signal fires were lit to tell of special occasions. The fires burning on top of Pukeone could be seen as far as away as Whakapuaka. A fire was lit on Pukeone following Wakefield’s acceptance of Nelson as a settlement site.
  • Rākauroa / Torrent Bay
    A bay approximately 10 km northeast of Kaiteriteri. The Anchorage is within the bay. Ngāti Tama notes that, as the name implies, the area was wealthy with trees and Ngāti Tama and Te Atiawa established ship building operations there after their arrival in the rohe. This name was also recorded in Peart's Old Tasman Bay and other documents. Ngāti Apa Tribunal evidence translated this as a type of tree. Rakauroa was the name of the bay, with many Ngāti Apa occupation areas.
  • Riuwaka River (was Riwaka River – also note Riuwaka River North & South Branches)
    A river flowing generally east from the confluence of Riuwaka River North Branch and Riuwaka River South Branch east of Wharepapa / Arthur Range into Tasman Bay / Te Tai-o-Aorere approximately 5 km north-northeast of Motueka. Te Atiawa states that this is: taonga wairua; Puketapu hapū have tribal accounts of relationships with the river; rivers are tapu; the mouth of the river is named after the tekoteko on top of Te Āwhina, which in turn were named after the tipuna who discovered Antarctica (Hui Te Rangiora); Riwaka is a spelling error and the “u” changes the meaning ; Riuwaka is the place that Hui Te Rangiora landed and was named by him because of its natural features.; Riuwaka is documented in Old Tasman Bay (Peart). Ngāti Rarua history: traditionally named the Riuwaka River – Riu is the name for the bilge of a waka or basin where water would gather. In this instance it is a reference to the puna or pools where the river emerges from within Papatuanuku. There are a series of pools below the Riuwaka resurgence and each pool has specific cultural purpose for the manawhenua iwi.
  • Rotomairewhenua / Blue Lake
    A lake west of Franklin Ridge and north of Rotopōhueroa / Lake Constance in Spenser Mountains approximately 25km southwest of Lake Rotoiti. Ngāti Apa Tribunal evidence states that this name means ‘Lake of peaceful lands’. This lake was used for the cleansing of male bones.
  • Rotomaninitua / Lake Angelus
    A lake at 1650 m on Robert Ridge in Travers Range adjacent to Bristol Pass and Hinapouri Tarn, approximately 6km west-southwest of Lake Rotoiti. Ngāti Apa Tribunal evidence states that this is the resting place of our spirits. When we depart this life into the next, Roto Maninitua refers to directing our wairua through to be washed, to bathe and to swim inside and underneath the snow, or should it be summertime, inside and underneath the mountain.
  • Rotopōhueroa / Lake Constance
    A lake below Franklin Ridge in Spenser Mountains approximately 26km southwest of Lake Rotoiti. Ngāti Apa Tribunal evidence, translates this name as the ‘long calabash’. This lake was used for the final cleansing of the bones of our female tipuna, before they were entrusted to be stored in and around Ngāti Apa’s sacred places in the Sabine Valley.
  • Separation Point / Te Matau
    A coastal point between Whariwharangi Bay and Mutton Cove extending into Golden Bay / Mohua approximately 18 km northeast of Takaka. Te Matau is an ancestral name and important to Ngāti Tama and Te Atiawa as it is one of the boundary markers between Onetahua and Motueka. The name was changed by D’Urville, but iwi still refer to this name and old title deeds support the name Te Matau. Te Atiawa Tribunal evidence also recorded this name (see A Riwaka Nga Hekenga p. 117, Tribunal casebook Northern South Island Inquiry). Ngāti Kuia and Ngāti Apa note that Peart in Old Tasman Bay translates the name as meaning the fish hook of Maui. It was the western most point of the tukuwhenua and an occupation area. An older name for this place is Te Matau-a-Maui.  Ngāti Rarua history: This translates as The Hook and represents the Eastern most point of Golden Bay and the Western tip of Tasman Bay. It was an area surrounded by a number of settlements of the local manawhenua iwi.
  • Te Horowai / Speargrass Creek
    A stream flowing from Robert Ridge approximately 1 km northeast of Rotomaninitua / Lake Angelus into Buller River approximately 8 km northwest of St Arnaud. Rangitāne and Ngāti Apa Tribunal evidence states that Ngāti Apa ancestor, Te Horowai, is buried here.
  • pupusprings.jpgPupu Springs - Karen Stade
    Click image to enlarge
    Te Kauparenui / Gowan River
    A river flowing north from Lake Rotoroa at Rotoroa (locality) into the Buller River approximately 1 km east of Gowanbridge. Ngāti Apa tribunal evidence translates Te Kauparenui as “The Great Division”.Te Kauparanui refers to the great earth rending that closed and formed the lake we have today and that in another lifetime Te Kauparenui shook and shook so hard that it created a huge tidal force that created the river of the Gowan.
  • Te Mamaku / Ruby Bay
    Te Atiawa and Ngāti Tama note that, as the name implies, the black tree fern was once plentiful and provided resources to the iwi. This was a pa site, an occupational reserve, a kai basket, and there was a waka landing site at McKee Domain. This was also a trading beach.
  • Te Waikoropupū River
    A stream flowing from the northern end of Walker Ridge generally northeast into Takaka River approximately 1 km northwest of Takaka. Spelling alteration from Waikoropupu River (“Te” and macron added to a recorded name). The English meaning for Te Waikoropupū is the bubbling spring waters. Te Atiawa and Ngāti Tama state that the river is in the sacred valley for Te Atiawa, outlined in evidence in Te Atiawa Tribunal hearing at Motueka. Ngāti Rarua translates this name as “Bubbling Waters” and notes that this is the home of the kaitiaki Huriawa who was responsible for keeping the waterways of Mohua clear and pristine. The waters have been utilised for many sacred occasions, such as blessings, cleansing and revitalisation of the unwell. Manawhenua iwi always offer karakia before entering this sacred place.
  • Tokangawhā / Split Apple Rock
    A rock just off the coast of Towers Bay adjacent to Tokongawha Point, approximately 2 km north of Kaiteriteri. Ngāti Tama and Te Atiawa note that the split is one of the boundary markers.
Marlborough Sounds
  • Te Aumiti / French Pass
    A strait between Rangitoto ki te Tonga / D’Urville Island and Te Waipounamu, northeast of Current Basin approximately 1 km northeast of French Pass (Anaru). Ngāti Kōata states that Te Aumiti is of significance to Ngāti Koata, who have many cultural historical stories and korero associated with Te Aumiti. Ngāti Kuia translates Te Aumiti as “The current that is swallowed.” This was the place where the Shag guardian of Kupe drowned. The story of the naming sets up part of the oral map for navigating the waters and the customs behind it. The full name is “Te Aumiro o te Kawau a Toru”.
  • Whareātea Bay (Durville Island).
    Misspelled name of bay/area on the north east side of Rangitoto ki te Tonga / D’Urville Island. Was also locally known as Whareata Bay.  
  • Tory Channel / Kura Te Au
    A strait separating Arapaoa Island from Te Waipounamu, extending generally east-west from Dieffenbach Point in Queen Charlotte Sound / Tōtaranui to West Head and East Head in Cook Strait. Te Atiawa and Ngāti Tama note that this: was an important mahinga kai and settlement site for Te Atiawa; was the Te Atiawa main highway; Te Atiawa continually monitor and defend this waterway today in Environment courts; Kura Te Au separates Arapaoa Island from the mainland in the Marlborough Sounds. Kura Te Au is named because of the red colour of the sea imparted by a variety of plankton and the  multitude of the crustacean krill; Kura Te Au is place where Kupe killed the giant wheke and the blood ran through the channel. Kurahaupo and Rangitāne note that this means “the red current”. When Kupe killed Te Wheke o Muturangi, the octopus bled into the current there, turning it red. The name also denotes the red Krill found all around the outer Sounds which is eaten by octopus and whales (hence the whaling presence) and is part of the Kupe oral map.
  • Whakakitenga Bay
    A bay adjacent to Wairangi Bay, at the northeast end of Squally Cove in Marlborough Sounds. Ngāti Koata state that the name Whakitenga bay was a misspelling; Whakakitenga Bay is the correct spelling.
  • Matapihi Bay (1km NE of Okiwi Bay)
    Bay north of Okiwi Bay at the foot of Matapehe.
  • Meretoto/ Ship Cove (Queen Charlotte Sound)
    cookwebberq.s.Sound.jpgWebber, John (1751-93). View in Queen Charlotte's Sound. London : Boydell, 1809 (oils from a sketch made on Cook's Third Voyage). Alexander Turnbull Library. B-098-015
    Click image to enlarge
    Te Atiawa and Ngāti Tama note that this cove is of significance as it is: of historical importance to previous iwi and Te Atiawa; Wahi Tapu; a burial site; tauranga waka. This is the original name, with reference to the bloody mere Rangitāne: Meretoto is the place where the first interaction between Cook's crew and Rangitāne Tupuna, such as Te Rangihouhia and Kahura first took place. Was also locally known as Ship Cove and was named Ship Cove (Meretoto) on NZ topographic maps.
  • Omhuri
    An isthmus separating Whakitenga Bay and Elaine Bay in Tennyson Inlet. Reported to be where Te Rauparaha and his taua entered into the Nelson region rather than travel around through Te Aumiti (French Pass)
  • Arapaoa Island
    An island adjacent to Tory Channel / Kura Te Au and Queen Charlotte Sound / Tōtaranui approximately 14 km northeast of Picton. Te Atiawa and Ngāti Tama note that this island is the location of traditions of Kupe but highly significant to Te Atiawa. Kupe finally dispatched whekenui with a massive Arapaoa (downwards blow) to its head. It is the spiritual home of Te Atiawa, with many Kaimoana sites, many papakaianga, fortified Pa sites, whaling sites, cultivation sites, waka landing, building waka, repairs. Arapawa is a spelling error. Ngāti Kuia Tribunal evidence notes that Ara means ‘to rise’ and ‘paoa’ is to strike with a weapon. The Island was named after Kupe’s rising stroke which killed the octopus Te Wheke o Muturangi. It features in waiata and stories of the iwi.
  • Greville Harbour / Wharariki
    A harbour on Rangitoto ki te Tonga / D’Urville Island extending generally northwest from Wharairiki Bay to between Ragged Point and Two Bay Point. Historical name of cultural association. Wharariki being the name of a particular type of red flax, with minimal fibre, which is an important taonga to Ngāti Koata people.
  • Matapara / Pickersgill Island
    An island in Queen Charlotte Sound / Tōtaranui adjacent to Arapaoa Island and Blumine Island (Oruawairua). Te Atiawa’s close association with Matapara / Pickersgill Island is through ancestry, conquest and customary occupation. This motu, like many others in Totaranui, was a strategic point for warfare, occupation and contains wāhi tapu for the iwi. The foreshore surrounding Matapara / Pickersgill Island was utilised for both offshore fishing and for preparation. Matapara / Pickersgill Island was a roosting and nesting place for the little blue penguin and the shag. It was also known for its kohekohe and tawa forest. During the turn of the century the island was used for harvesting of wheat crops, speargrass and cocksfoot. Matapara is the traditional name for the island and has been used by whanau and hapu since the conquest of Totaranui by Te Atiawa.
  • Pelorus Sound / Te Hoiere
    Ko Matua Hautere te Tangata, Ko Kaikai-a-waro te taniwha, Ko Te Hoiere te Waka, Ko Ngāti Kuia te Iwi Ngāti Kuia notes that Inskull in Place Names of Marlborough (p. 55) translates this name as a type of tree, and it was the name of the waka, captained by Matua Hautere, which brought Ngāti Kuia to the area. It was guided here by their two kaitiaki, Kaikaiawaro and Ruamano. It forms a substantial part of Ngāti Kuia identity, history and place of occupation. Ngāti Toa history: Te Hoire is the traditional name given to Pelorus Sound by Ngāti Toa; the sound was renamed by Lieutenant P. Chetwode after the ship he commanded: the HMS Pelorus. Pelorus Sound was an area of concentrated Ngāti Toa occupation and control; the iwi were considered to be the ‘direct owners’ of the Sound, as well as the connected valley and river, in the 1830s and 1840s. Ngāti Toa first came into possession of the region following their conquest during 1829 and 1830. According to historian W.J. Elvy, at the time of Te Rauparaha’s raids, Ngāti Kuia held the Pelorus Sounds and the valley. The invaders, however, “cleaned up the districts pretty thoroughly, reducing the survivors to slaves, or forcing them to hide in the mountainous fastness of the hinterland.” Hopai Pa located in Crail Bay, is one famous battle site at which Ngāti Toa were victorious . Two Ngāti Toa pa, the Canon point pa, and Te Akaroa pa, are located at Port Ligar. Another site of significance was the stream mouth at Clova Bay, which was given the name Totaranui. This was a landing site for waka that crossed from Omere on the Wellington South Coast, and was used extensively during the invasion and conquest of Te Tau Ihu.
  • Queen Charlotte Sound / Tōtaranui
    Te Atiawa and Ngāti Tama state that: Totaranui waterways are the veins of Te Atiawa, each and every bay is highly significant to Te Atiawa; Totaranui is the original Te Reo name; Totaranui was bountiful inTotara. Following a series of taua 1827–1830, Ngāti Toa established themselves at a number of locations in the Marlborough Sounds, including Queen Charlotte Sound. There were a number of Ngāti Toa pa sites in Totaranui, including Te Rei o Karaka pa at Karaka Point, and Ngakuta Point Pa. Ana-o-koha, located in the Dieffenbach point area, is the site of an historic battle, at which Ngāti Toa successfully repelled and defeated an attempted ambush . Another site of significance is Ship Cove, an important tapu area where the daughter of Te Pehi Kupe is buried. Colonel Wakefield, while collecting signatures for the Treaty of Waitangi in 1840, encountered a large Ngāti Toa group.
Marlborough
  • Waikārapi Lagoon
    Was Vernon Lagoon near Blenheim. Waikārapi refers to the series of channels and weirs (Pa-tuna) built around the wider lagoons area to trap the various species of fish and birds that frequented the wetlands. This was specifically identified in the map of the Wairau drawn by Ihaia Kaikoura and copied by Ligar in 1847. Was locally known as Vernon Lagoon.
  • Hikurangi/ Goulter Hill
    4km Southwest of Renwick
  • Vernonlagoon1.JPGWaikārapi Lagoon. Colin Davis, Department of Conservation, South Marlborough Area Office
    Click image to enlarge
    Kahuroa Hill
    11km NE of Havelock, nr Pelorus Sound Ko Kahuroa te Maunga, Ko Te Hoiere te Awa, Ko Ruapaka te Kainga, Ko Ngāti Kuia te Iwi. The name means the long cloak and comes from the mist which shrouds it. Ngāti Kuia Tribunal evidence states that this maunga has an urupa on it and forms part of waiata, and stories. It is above the Ngāti Kuia land at Ruapaka, and forms part of the pepeha for the whanau of that place. The name means the long cloak and comes from the mist which used to shroud it. It is part of the Ngāti Kuia pepeha for the Ruapaka Kainga.[ Notes for Polynesian Society, Smith; and Ngāti Kuia evidence, Moses.]
  • Otauira Pā               
    On the shore of Robin Hood Bay, South of Port Underwood. Rangitāne Tribunal evidence records that this site translates as ‘Water rushes.’ This was an occupation and fishing area. Otauira is the Rangitāne Pa site at the mouth of the Waikutakuta stream where Ihaia Kaikoura drew the map of the Wairau for Ligar in 1847.
  • Te Ana-o-Rongomaipapa Bay
    Between Rarangi and Whites Bay. Rongomai Papa was the Rangitāne Tupuna who established Pukatea Pa and  ambushed and killed the giant flying Taniwha Ngarara Huarau. The cave that he hid in is still visible to the present day - Te Ana o Rongiomai Papa. [Tuiti Macdonald MP wrote this story for S.Percy Smith in 1906.]
  • Te Ope-a-Kupe Rock
    A rock near Port Gore. Te-Ope-a-Kupe was named by Kupe and means the group of kupe. It is a tauranga waka what was used by him for his waka Matahourua and succeeding generations of his descendants. Ngāti Kuia korero states that this was one of the landing places of Matua Hautere and his waka Te Hoiere, Te Whakamana and his waka Te Ara-a-Tawhaki and Tukauae and his waka Tahatu. There is is a rock at the site which our people says has his foot print which shows where he and his crew got of his waka. This place is still used today as a safe anchorage by Ngāti Kuia.
  • Te Pokohiwi / Boulder Bank
    Between Wairau River and White Bluffs. According to Inskull Te Pokohiwi translates as the “shoulder” and this name refers to the shape and position of the Bank. Was also locally known as Boulder Bank.
  • Ōhinemahuta River
    A stream flowing from Richmond Range near Mount Sunday into Wairau River approximately 4 km northwest of Renwick. Old Rangitāne/Ngāti Mamoe name of place where Tupuna Hine Mahuta lived hence – Ōhinemahuta.
  • Ōpaoa River
    A river flowing from the confluence of Omaka River and Ruakanakana Creek approximately 2 km northeast of Renwick generally east into Wairau River at Wairau Bar. Ngāti Rarua translates this as Smoking River, which can be described as the mist or fog rising off this particular river giving the appearance of smoke hanging over the water. This awa along with the Wairau was an important food resource and integral part of day to day life for Ngāti Rarua. Rangitāne notes that Inskull in Place Names of Marlborough (p. 54) translates ‘Paoa’ as smoke – ‘smoky river’. There are several different explanations for the name. This place was very swampy and the river became murky with the appearance of smoke. It is also known as the place of the grey teal. The tupuna Paoa had a pa there and the place was named after him.
  • Ōraumoa / Fighting Bay
    A bay east of Te Whanganui / Port Underwood approximately 17km east south-east of Picton. Ngāti Toa history: Fighting Bay, located on the Eastern Coast of Te Tau Ihu was a very important Ngāti Toa tauranga waka. It was located in close proximity to the concentrated Ngāti Toa settlement at Port Underwood, and provided a site from which Ngāti Toa could travel directly across Te Moana o Raukawa to the South Coast of Wellington. It was the site of a battle with Ngai Tahu and hence its name. Rangitāne history: Raumoa was the name of a Rangitāne ancestor who lived in the Wairau and travelled to this place for special seafood hence the name O-Raumoa, - the place of Raumoa.
  • Pukatea / Whites Bay
    A bay approximately 1 km northeast of Rarangi where Pukatea Stream flows into Te Koko-o-Kupe / Cloudy Bay. Ngāti Rarua records that this was the first landing place of the Ngāti Rarua taua in the fight for Wairau. It was also a former fishing reserve of Rarua, Toa and Rangitāne, and a campsite and mahinga kai site. Rangitāne history: Puketea translates as a type of tree. This was where a Kurahaupo tupuna killed a taniwha. It was an occupation and fishing area.  Pukatea was a traditional tauranga waka and was used by Te Rauparaha and his allies during the invasion of Te Tau Ihu in 1827 (Inskull). This site was taken as a reserve in the 1950s.
    whitesbay1.jpgSouthern end of Cook Strait's telegraph cable - Whites Bay 1871, Marlborough Museum, 0000.900.0735
    Click image to enlarge
  • Ruakanakana Creek
    A stream flowing near Renwick into Omaka River (was known as Gibsons Creek). Ruakanakana Creek is the place where weirs were dug to trap Lamprey eels (kanakana) on their annual migration – hence Rua Kanakana or pit of the Lampreys.
  • Takapōtaka / Attempt Hill
    A hill at 729 m on Rangitoto ki te Tonga / D’Urville Island approximately 8 km north-northeast of Te Aumiti / French Pass. This was the name of the hill prior to European settlement.
  • Te Anamāhanga / Port Gore
    A bay between Cape Lambert and Cape Jackson adjacent to Cook Strait approximately 3 km northeast of Endeavour Inlet This name translates as ‘Twin bays’. Te Huataki of Rangitāne landed here. Ngāti Kuia and Ngāti Apa also lived here.
  • Te Hoiere / Pelorus River (see Pelorus Sound above)
  • Te Koko-o-Kupe / Cloudy Bay
    A bay approximately 15.5km north-east of Blenheim extending from Robertson Point to White Bluffs/Te Parinui o Whiti and eastwards into Cook Strait. Ngāti Rarua history: The scoop of Kupe. The place that was scooped out or formed by legendary explorer Kupe. Rangitāne translates this name as the scoop of Kupe. Kupe’s waka went aground at Wairau (Vernon) Lagoons. Ngāti Toa history: The wider Cloudy Bay region, encompassing both the Wairau and Port Underwood, was an extremely significant area to Ngāti Toa. Ngāti Toa was acknowledged to have possession of this Bay and it was a location of concentrated occupation. Ngāti Toa had both residences and cultivated lands in Cloudy Bay. Cloudy Bay was also an important centre of the thriving whale industry. The population did decrease in the late 1840s, however Ngāti Toa did maintain their occupation of Cloudy Bay. Ngāti Rarua history: This name originates from the time of Kupe and his infamous pursuit of the octopus Te Wheke o Muturangi. The name literally translates as the Scoop of Kupe meaning the place or area that was scooped out or formed by Kupe.
  • Te Tara-o-Te-Marama / Mount Freeth
    A hill at 625 m approximately 3 km southwest of Picton. Te Atiawa and Ngāti Tama note that this was the maunga used for the whanau in the area; Ko Tara o te Marama – meaning ‘it is the peak of the moon’ (‘tara’ as in Taranaki). Rangitāne note that Insull’s Place names of Marlborough (pp. 47 & 51) translates this as ‘Moonlight mountain’. At a certain time of the year the rising moon follows the gradient of the maunga.
  • Te Whanganui / Port Underwood
    Ngāti Rarua: Te Whanganui means the large harbour. Ngati Toa: This was the largest and most concentrated area of Ngati Toa settlement in Te Tau Ihu; their interests in Port Underwood were based upon both conquest and effective occupation. According to Dieffenbach there were approximately 400 Ngāti Toa living in the ‘Cloudy Bay’ area. This community was led by Nohorua, Te Kanae and Rawiri Puaha and was centred on the mission and whaling industry. A pa and urupa were located on Horahora Kakahu Island in Te Whanganui. This is a very important historical and cultural site as this was the location at which a number of Ngāti Toa chiefs signed the Treaty of Waitangi.
  • Tokomaru / Mount Robertson
    A hill at 1036 m on Robertson Range approximately 6 km southeast of Picton. Ngāti Toa history: Tokomaru is a site of cultural significance. It is recognised as being te maunga o Ngāti Toa ki roto i te Wairau. Ngāti Rarua history: Sacred mountain for Ngāti Rarua within the rohe of Wairau. The name has origins within pre Aotearoa settlement and relates to a peak of the same name in Hawaiki. Translation refers to a toko or pole used within a tuahu or shelter erected on the summit of this peak that gives maru or shelter and protection over the whenua or plains of Wairau. Its significance to iwi is immense and is enshrined within the pepeha “ Ko Tokomaru te pae maunga, ko Ngāti Rarua te iwi…”.
  • Tūtūmāpou Hill
    A hill at 319 m south of Te Hoiere / Pelorus River approximately 1.5 km west of Canvastown and 10 km west-southwest of Havelock. Ko Tutumapou te Maunga Ko Te Hoiere te Awa Ko Te Hora te Pa Ko Ngāti Kuia te Iwi The Ngāti Kuia translation means the bird snare (Tutu) in the mapou tree. The mountain was a regular food source of kereru for Te Hora Pa, which still in use today. It is part of the Ngāti Kuia pepeha for Te Hora Marae.
  • Waikutakuta / Robin Hood Bay
    A bay southwest of the entrance to Te Whanganui / Port Underwood approximately 10 km southeast of Picton. Ngāti Rarua describes this as the place of the water rushes. It was a former site of large Māori settlement, and an extensive cultivation site. This was the name used by Ngāti Rarua for Robin Hood Bay. However, the original name may only relate to a feature or natural marker within the Bay. The name Waikutakuta is recorded in a waiata tawhito of Ngāti Rarua titled “Ka kati i te karaka”. Ngāti Toa history: Robin Hood Bay, located in the south of Port Underwood was an area of concentrated Ngāti Toa occupation. The settlements of Cloudy Bay and Port Underwood were predominantly coastal, at locations such as Robin Hood Bay, however inland areas were heavily utilised for various resources. In the 1830s Te Rauparaha had a home in Robin Hood Bay, which he visited and occupied during the whaling season each year. Te Rongo, wife of Te Rangihaeata, is said to be buried at Robin Hood Bay. She was killed at Wairau during the 1843 incident.

2014

Tohu Whenua - sites of significance

A Nelson City Council produced series of videos on landmarks and sites of significance, produced to celebrate Te Wiki o te Reo Māori 2019


          

Comment on Working with vtkDataArrays: 2019 Edition by Allison Vacanti

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re: compile times, binary size -- these are definitely the bane of generic code! The vtkArrayDispatch utility helps quite a bit in that regard. Even if only using AOS arrays, there are a number of dispatchers that pare down the list of generated functor implementations. For example, <code>DispatchByValueType<Reals></code> only generates paths for float/double arrays, and <code>Dispatch2SameValueType</code> takes two arrays but only generates paths where the arrays have the same value type. By using the vtkDataArrayRange utilities, the same implementation can be used for both the optimized, known-type paths and a slower fallback path using vtkDataArray. This makes it much easier to just specialize an algorithm for common arrays without having to maintain two implementations of the same algorithm. This helps developers limit the number of generated optimized paths without sacrificing functionality. Together, these provide quite a bit more flexibility and control over codegen than the older GetVoidPointer/vtkTemplateType macro system.
          

CPU PCB computer board blue glow macro

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Download CPU PCB computer board blue glow macro Wallpapers from WallpaperFool.com
          

AMENDEMENTEN 1 - 20 - Ontwerpverslag Macrofinanciële bijstand aan het Hasjemitisch Koninkrijk Jordanië - PE643.221v01-00

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AMENDEMENTEN 1 - 20 - Ontwerpverslag Macrofinanciële bijstand aan het Hasjemitisch Koninkrijk Jordanië
Commissie internationale handel
Luisa Regimenti

Bron : © Europese Unie, 2019 - EP
          

Nato fejrer 70 år med debat om hjernedød

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Nato fejrer 70 år i næste uge, og var fødselaren et menneske og dødelig, var det nok på tide at overveje pension. Men ligefrem "hjernedød", som den franske præsident, Emmanuel Macron, har ka…
          

¿Qué es la economía naranja del presidente Iván Duque?

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La economía colombiana no atraviesa un buen momento y el mundo lo sabe. Las agencias calificadoras de riesgo están al borde de declarar la deuda colombiana como deuda basura debido a las inestabilidades macroeconómicas del país. La dependencia del petróleo y demás materias primas hacen que muchos economistas y analistas financieros se pregunten para dónde […]

La entrada ¿Qué es la economía naranja del presidente Iván Duque? se publicó primero en Muy Financiero.


          

Guillaume Tabard: «Une alliance implicite avec Darmanin à la métropole» de Lille

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CONTRE-POINT - Martine Aubry, candidate à un quatrième mandat, sait qu’elle devra composer avec ses puissants voisins macronistes.
          

Logitech G402 Hyperion Fury FPS Gaming Mouse with High Speed Fusion Engine (910-004069) $19.99

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Logitech G402 Hyperion Fury FPS Gaming Mouse with High Speed Fusion Engine (910-004069) $19.99 free shipping with Amazon Prime
  • World's fastest gaming mouse: Fusion Engine technology and 1MS report rate enables tracking speeds of up to 10 meters/second (420 ips)
  • 8 programmable buttons: Customize your gaming experience and save button settings to the onboard memory
  • 4 on-the-fly DPI settings: Shift instantly from pixel precise targeting to lightning fast maneuvers (250 to 4000 DPI)
  • 32-bit Arm Processor: Powers incredible tracking speeds; allows you to save and playback your macros
  • Lightweight, streamlined design: Optimal weight, shape and feel for absolute gaming comfort and fast, furious swipes

          

Review Motorola One Macro: miopia, astigmatismo e boa autonomia [análise/vídeo]

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Já deu o prazo de vida de uma semana e a Motorola tem mais um smartphone da risco Motorola One. Ele é o Motorola One Macro e que tem porquê principal recurso uma lente que faz fotos em modo macro. Além do novo recurso fotográfico, leste celular troca o processador Snapdragon por um Mediatek, tem […]
          

色々なシーンに活躍してくれるSUPREME★シュプリーム パーカー コピー無地生地フード付きスウェットシャツスーパーコピーコットン生地ストレスを軽減

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お洒落に着られて、大人らしくセンス良く、着回し抜群の実力派SUPREMEパーカーコピーです。 http://www.pabrand.com/ 着るだけでお洒落に一歩差のつく着回しを叶えて、品質にこだわり、より良いものづくりに能的なデザイン・耐久性・素材・縫製といったひとつひとつに抜群のアイテムです。supreme パーカー コピー 通販 http://www.pabrand.com/brand-172.html 無地なので合わせやすく色々なコーディネートが楽しめます。 商品番号:pab2018SUP-WT078LY 品  番:pab2018SUP-WT078-1 ブランド:シュプリーム SUPREME 市場価格: 8640円 販売価格: 7200円 http://www.pabrand.com/product-93172.html ▼メセッジ▼ ◆ポイント◆ ◆※この商品の素材感とサイズ感の特性上、若干の誤差がございます。 ◆いらっしゃいませ!paburanndo@gmail.comへ ◆新規会員登録すると、最安いサービスが表示されます。 ◆当店ではお買い物の注意はご注文のアイテムがあれば、お客様にぜひご注文確認してくれメールで連絡させていただいております。 ◆当店ではお問い合わせについてはメールアドレスのかげでサーバーにてご迷惑をおかけしました、申し訳ございません。 ◆お買い物の前に問い合わせ場合にはpaburanndo@gmail.comまでご連絡くださいませ。 http://golfcopy.com/wnumsr/ エルメス偽物 ブランド 販売 http://lyze.jp/wassupp/diary/1/ http://smithggg.2339049.n4.nabble.com/template/NamlServlet.jtp?macro=user_nodes&user=6276
          

Japanese Food Adventures In LA

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Well, we've got some strange, but fun Japanese foodie events happening soon. We have a rice lecture. Yes, a real rice lecture and tasting. We also have a LACMA sending off its Japanese art exhibit, Every Living Thing: Animals in Japanese Art with both a special tour and dinner celebrating the subject. And it happens to be Vegan.


Sat, Nov 23, 2pm or 4pm
JAPAN HOUSE Salon, Level 5
6801 Hollywood Blvd.
Los Angeles, CA 90028
Free, Must RSVP

*Yes, really a rice tasting

Since 1971, the Japan Grain Inspection Association has conducted rice taste sensory tests on a national scale, ranking each regional variant through rigorous scientific assessment to determine the best tasting rice every year. (*) This workshop features a lecture led by the National Agricultural Research Organization of Japan (NARO) in which participants will learn about Japanese short-grain rice and its regional variants, and the best way to cook rice and how to pair side dishes to complement its flavor.
Following the lecture, participants will join in a professional-level sensory test of rice, sampling four types of cooked white rice. Participants will also receive a souvenir as a small token of appreciation to take home.


Saturday, December 7, 2019 | 10 am–4 pm
Japanese American Cultural & Community Center
244 S. San Pedro St. Los Angeles
$90 JACCC MEMBER | $100 GENERAL

LEARN TO MAKE YOUR OWN JAPANESE NEW YEAR TRADITIONAL OSECHI!
Yoko Maeda Lamn, founder of Hakko, returns to JACCC’s culinary team to create several traditional Japanese New Year dishes. Learn the craft of regional styles of soups and vegetable-based dishes with explanations of the historical basis on this traditional cuisine.
Saturday, December 7, 2019 | 10 am–12 pm
Japanese American National Museum  

244 S. San Pedro St. Los Angeles
$80

Make soba using fresh, stone-milled artisanal flour from Japan and authentic soba tools. This soba will be served in the classic way: cold with fresh soy-based dipping sauce, toppings, and spices. 
Soba is a type of noodle traditionally made from buckwheat flour, or a combination of buckwheat and wheat flours. In Japan, many people celebrate special occasions by eating soba. For example, many celebrate New Year’s Eve by eating toshikoshi soba or when moving into a new residence, people will serve their new neighbors hikkoshi soba.

Sun, Dec 8, 2019 5:30 pm–8 pm 
Smidt Welcome Plaza  |  LACMA 
$100 LACMA members, $134 LACMA members with wine-tasting; $110 general public, $144 general public with wine-tasting


Start this fun evening with a tour of the exhibition Every Living Thing: Animals in Japanese Art, which celebrates one of the most distinctive aspects of Japanese art: the depiction of animals. Underpinned by Japan's spiritual heritage of Shintō and Buddhism, the Japanese reverence for nature—and the place of animals within that realm—is expressed in a variety of artworks. You will find artistic representations of animals real and imagined, including lions, dogs, cats, fish, insects, dragons, and phoenixes. Learn about the various roles animals have played in Japanese culture.
Then move to Ray’s & Stark Bar to enjoy a creative vegan Japanese dinner specially designed by executive chef Phillip Martin, featuring seasonal ingredients. The vegan menu is inspired by the Buddhist ritual of releasing captured animals that was practiced in Japan.



          

Senior Data Analyst - William E. Wecker Associates, Inc. - Jackson, WY

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Ideally, an excellent working knowledge of Base SAS, SAS/STAT, SAS SQL, and advanced SAS DATA step and macro programming on a UNIX and Windows platforms;
From William E. Wecker Associates, Inc. - Mon, 22 Oct 2018 06:14:12 GMT - View all Jackson, WY jobs
          

Milli Savunma Bakanı Hulusi Akar’dan NATO’ya çağrı

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NATO’nun 70. kuruluş yıl dönümüne denk düşen Londra toplantısı öncesi Euronews’da yayınlanan makalesinde Akar, Türkiye’nin NATO’ya karşı tüm yükümlülüklerini yerine getirdiğini ancak NATO müttefiklerinin Türkiye’yi Suriye sınırında 'YPG-PKK ile mücadelede' yalnız bıraktığını söyledi.

Milli Savunma Bakanı Hulusi Akar, Salı günü Cumhurbaşkanı Recep Tayyip Erdoğan’ın da katılacağı NATO liderler toplantısı öncesinde yaptığı açıklamada, Türkiye’nin NATO’ya karşı tüm yükümlülüklerini yerine getirdiğini ancak NATO müttefiklerinin Türkiye’yi Suriye sınırında "YPG-PKK ile mücadelede yalnız bıraktığını" söyledi. 

NATO'nun 70. kuruluş yıl dönümüne denk düşen Londra toplantısı öncesi Euronews'da yayınlanan makalesinde Akar, "NATO, dünyada terörün tüm tezahürleriyle ortadan kaldırılmasında kilit bir öneme sahiptir. Ancak bu mücadele tam kararlılıkla gerçekleştirilmelidir. Aksi takdirde terörle mücadele tümden sorgulanır hale gelebilir" dedi.

Zirvenin Macron'un NATO'nun beyin ölümü yaşadığı tartışmalarının ardından yapılacağını anımsatan Akar, "Gerilimin yüksek olduğu geçen yılki NATO liderler zirvesinden de akıllarda kalan NATO'nun ömrü ve faydalı olmaya devam edip etmeyeceği yönündeki tartışmalardı. Ancak bu yılki zirveye yaklaştığımız şu günlerde tartışma konularından biri de Türkiye. Bazı çevreler, ulusal güvenliğimiz için attığımız adımları - örneğin Suriye'nin kuzeyindeki son operasyonumuzu - NATO ittifakını hiçe saydığımızın kanıtı olarak gösterme çabasında. Tabii bu iddialar, mantık dışı ve konuya ilişkin gerçeklerin saptırılmasından başka bir şey değil" dedi.

'TÜRKİYE NATO'YA KARŞI YÜKÜMLÜLÜKLERİNİ YERİNE GETİRDİ'

Akar, Türkiye'nin, bir üye ülkenin yapabileceği en anlamlı biçimde NATO'ya karşı yükümlülüklerini yerine getirmeyi sürdürdüğünü, Kore Savaşından Balkanlara, Afganistan'a kadar askerlerimizin dünyanın her yerinde NATO görevlerinde, harekâtlarında ve tatbikatlarında yer aldığını, insani misyonlarda kilit rol oynadığını söyledi.

NATO müttefiklerinden gelen tepkileri son derece haksız ve anlaşılmaz bulduğunu kaydeden Akar yazısını şöyle sürdürdü: "Çünkü Türkiye bugüne kadar güvenlik ve terörle mücadeleye büyük bir ciddiyetle yaklaşmış, bu mücadelesini etkinlikle, aynı zamanda NATO müttefikleri ile en üst düzeyde koordineli biçimde yürütmüştür. Türkiye, yıllardır "Suriye'de DEAŞ'e Karşı Koalisyonun" askeri çabalarında en önde yer almıştır. DEAŞ ile göğüs göğüse çarpışan tek NATO ordusu, Türk Silahlı Kuvvetleridir. Bu mücadelede imkânlarımızı ve bölgede terörle mücadele operasyonlarında kilit rol oynayan İncirlik üssümüzü koalisyonun hizmetine açtık.

'NATO AİLESİ BİZİ YAKINDAN TANIMAKTA, BİRLİKTE PLANLAR YAPTIK'

NATO ailesi bizi yakından tanımaktadır. Birlikte planlamalar yaptık, dünyanın her yerinde operasyonlarda, sahada birlikte çalıştık. Her gün istihbarat paylaşıyor, terörle mücadele çabalarımızı koordine ediyoruz. Aslında en ideali, bu ittifakın bizimle birlikte hareket etmesi, Türkiye'nin ciddi güvenlik kaygılarına birlikte çözüm araması ve bizim yanımızda durması olurdu. Tek başına başlatmak zorunda kaldığı Barış Pınarı Harekatında Türkiye; masum sivillerin, tarihi ve kültürel yapılar dâhil altyapının zarar görmemesi için, ülkedeki kırılgan durumun kötüleşmemesi için her türlü önlemi almıştır. Sonuçta Türkiye, Suriye halkının acılarını dindirmek için en büyük yükü omuzlamış bir ülkedir".

'LOS ANGELES NÜFUSUNA DENK SURİYELİ KARDEŞİMİZİ AĞIRLIYORUZ'

Batılı okuyucuların kafasında daha somut bir imaj oluşturması için yazısında Türkiye'nin yıllardır misafir ettiği Suriyelilerin sayısını da Amerika'nın Los Angeles şehrinin nüfusuyla örneklendiren Akar, "Los Angeles nüfusuna denk düşen 4 milyona yakın Suriyeli kardeşimizi - ki bu arada bunlardan yüz binlercesi YPG terör örgütünün zulmünden kaçan Kürt kardeşlerimizdir - ülkemizde ağırlıyoruz. Türkiye'nin Suriyeli sığınmacıların eğitimi, sağlığı ve barınması için bugüne kadar harcadığı para 40 milyar dolardır. Biz, Suriye'de daha fazla yıkımın ne sonuçlar doğuracağının herkesten daha fazla bilincindeyiz ve bu yüzden de Suriye'ye barış ve istikrarın gelmesini istiyoruz. Operasyona başladıktan sonra teröristlerin bölgeden çekilmesi için iki kez harekâta ara verdik ancak YPG'li teröristlerin ihlalleri hala sürmektedir. Türkiye'nin mücadelesi Kürtlerle değildir ve bizim daha önceki harekatlarımız bunu hiçbir şüpheye yer bırakmayacak biçimde göstermiştir" dedi.

'TÜRKİYE OLARAK BİZ BURADAYIZ VE MÜTTEFİKİZ'

Milli Savunma Bakanı Akar, yazısını şöyle bitirdi: "Türkiye Avrupa'daki yaygın tabirle "kirli banyo suyunu tahliye ederken sudaki bebeği feda etmeyecek" yani önemsediği değerleri koruyacaktır. Bu anlamda Türkiye, NATO içinde tüm yükümlülüklerine bağlıdır. Hem mali katkılarımızla hem de kahraman askerlerimizin çabalarıyla bu yükümlülüğümüzün arkasında durmaktayız. Aynı zamanda önümüzdeki yıllarda ittifakın, gerçek misyonuna ve ilkelerine bağlı, her bir müttefikin güvenlik ve emniyetinin sigortası olan daha güçlü ve sağlıklı bir birliğe doğru evrileceğini umuyoruz. NATO, değişen zamanlara ve ortaya çıkan ihtiyaçlara cevap verecek esnekliğe sahip, güçlü ve çevik bir örgüt olduğunu göstermiştir. Türkiye olarak biz buradayız ve müttefikiz.".


          

Contre les violences faites aux femmes, le projet de Décidons Paris !

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L’inaction des pouvoirs publics contre les violences faites aux femmes et les féminicides, ça suffit ! Alors que les associations réclamaient 1 milliards contre les féminicides, les annonces d’Édouard Philippe ce lundi restent largement insuffisantes. Une fois de plus, Emmanuel Macron qui prétendait faire de cette question une priorité du quinquennat, se soumet finalement à une…
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L’article Contre les violences faites aux femmes, le projet de Décidons Paris ! est apparu en premier sur Décidons Paris !.


          

Commentaires sur Listes communautaires : Macron prépare la partition musulmane de la France ! par ANTI-CENSURISLAMIQUE

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Macron refuse (une fois de plus) de se mettre à dos ses petits protégés!
          

Commentaires sur Macron prépare une chaîne Arte bis franco-algérienne payée par la France : pour défendre l’Algérie du FLN ? par MEDHIAPARTHEiDiSLAMIQUE

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Comme si Europe1 (Qatar), Euronews (Egypte), Arté (Iran), FranceTVinfo (Maghreb) ne suffisaient pas!
          

Commentaires sur Les propos peu diplomatiques d’Emmanuel Macron sur l’OTAN par MEDHIAPARTHEiDiSLAMIQUE

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Tant Macron, l'OTAN qu'Erdogan sont les amis des Terroristes islamistes D'ailleurs c'est ce derniers qui a ouvert en grand les portails de l'Europe à ces Terroristes islamistes qui ont causé le massacre le soir du vendredi 13 novembre 2015 au Bataclan!
          

Introducing Biology's newest faculty

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Newsletter issue:
People:
Neda Bagheri
Alejandro Rico-Guevara
Kristiina Hurme
Jeff Rasmussen
Adam Steinbrenner
Julie Theriot

Welcome to UW Biology's newest faculty members! These renowned scholars and researchers come from all across the country and have added tremendous expertise to the UW Biology community. A special thank you to the Washington Research Foundation, Jodi Green, Mike Halperin, Walt Halperin, Margaret Hall, and the late Ben Hall for making these hires possible!

Here is a brief look at the newest members of the UW Biology community:

Neda Bagheri
Assistant Professor
WRF Distinguished Investigator

Education:

PhD in Electrical Engineering from UC Santa Barbara
Postdoc in Biological Engineering from MIT

Expertise:

My lab—aptly named the MOdeling DYnamics of Living Systems (MODYLS) Lab—employs tools across engineering and applied math to help explain unintuitive biological observations and to gain fundamental insight. My primary areas of expertise include systems biology, dynamical systems, and control theory. An exciting application of our research that integrates skills across these domains involves predicting emergent dynamics within and among cell populations using multi-scale, multi-class computational models.  

Most fascinating research discovery:

Understanding how the context of the microenvironment shapes cell decisions.

Accolades:

NSF CAREER Award, National Science Foundation Directorate for Engineering

Distinguished Speaker for the Accelerated Discovery Forum at IBM Research-Almaden and Keynote Speaker at multiple international conferences

Mindlin Foundation Public Lecture at University of Washington

Cornew Innovation Award, Northwestern University Chemistry of Life Processes

Extracurricular:

  1. If not a Biology professor, I would be: Hiking above tree line.​
  2. Favorite hobbies:​ I love being outside—hiking, cycling, climbing—and playing ultimate frisbee.​
  3. What is one thing you will never do again? Learn how to drive a motorcycle through trial and error. (Take a class!)
  4. What motivates you to work hard? I love to enable, promote, and empower the next generation of citizens and thought leaders.
  5. If you could choose to do anything for a day, what would it be? Paraglide across the alps (with proper instruction and safety, of course)

Kristiina Hurme
Lecturer, full-time

Education:

B.A. Princeton University
Ph.D. University of Connecticut

Expertise:

I’m a Behavioral Ecologist that has studied parental care, territoriality, male-male combat, vocal communication, mating and courtship in frogs, birds, and fish throughout the Neotropics. In zoos I designed enrichment for monkeys and frogs, and used positive reinforcement to train monkeys and sea lions, skills that I am now using to study wild hummingbirds!

Most fascinating research discovery:

For my dissertation, I studied maternal care in a neotropical frog, Leptodactylus insularum, in Panama. These large frog mommas often care for schools of 1000s of tadpoles in temporary ponds. I found that they reached metamorphosis surprisingly quickly, growing from egg to juvenile froglet in about two weeks! In order to grow and develop so fast, these tadpoles were constantly active and foraging. This activity attracted a lot of attention from predators, such as fishing spiders and herons, and I found that the only schools that survived to metamorphosis had a mother guarding them. These courageous moms not only fought off predators (even my hand!), but also communicated with the schools, guiding them to safe foraging areas. Some males have large and muscular arms with thumb spines (intrasexually selected weapons), and the only males I observed breeding were huge and covered in battle scars.

Accolades:

I received Honorable Mention for the Graduate Student Teaching Excellence Award at the Ecology and Evolutionary Biology Department, University of Connecticut.

Our recent paper on Intrasexually Selected Weapons was selected as the cover of the latest volume (five issues) of Biological Reviews: onlinelibrary.wiley.com/loi/1469185x/year/2019

Extracurricular:

  1. If not a Biology professor, I would bean artist, a zookeeper, a scientific illustrator, a wildlife film maker – something that allows me to observe and appreciate the natural world and share it with others.
  2. What is your favorite book? “My Family and Other Animals”, by Gerald Durrell. Growing up as a young naturalist on a Greek Island – what a dream!
  3. What is your proudest accomplishment? Working as a team with my husband Alejandro. In life, raising our daughters, Sierra and Aurora. In research, training wild hummingbirds to voluntarily drink from intimidating experimental setups, resulting in a stress-free way to measure behavior and physiology. Check out the PBS nature documentary “Super Hummingbirds” for examples!
  4. What are your hobbies? Fencing, anything related to horses, nature photography, exploring nature with two little kids.
  5. What makes you happy? Seeing the “aha” moment in students, sharing a love and enthusiasm for biology and observation of the natural world, showing students cool and surprising animal behaviors, often with the help of David Attenborough!
  6. Why did you choose to work at UW Biology? I fell in love with the department because of how everyone prioritizes excellence in teaching biology and collaborates on assessing how students learn! I am so excited to be in a place where I will be supported and encouraged!

Jeff Rasmussen
Assistant Professor
WRF Distinguished Investigator

Education:

2011, Ph.D., Molecular and Cellular Biology, University of Washington, Seattle, WA
2002, Sc.B., Computational Biology, Brown University, Providence, RI

Expertise:

I am broadly interested in cell and developmental biology, in particular how cells adopt and maintain specific shapes. My lab uses zebrafish to gain molecular and cellular insights into the development and repair of somatosensory neurons, which are some of the largest and most complex cells in the body. Somatosensory neurons build enormous and elaborate peripheral axons that innervate the skin to detect pain and touch. Our current focus is on understanding interactions between these somatosensory axon endings and the various specialized cell types they encounter in the skin.

Most fascinating research discovery:

As a graduate student, I discovered that cells within the worm embryo could fuse with themselves to form tiny, single-cell tubes in the shape of a donut.

Accolades:

2018, Hilde Mangold Postdoctoral Presentation Award, Society for Developmental Biology (SDB) 77th Annual Meeting, Portland, OR

2013—2016, Postdoctoral Fellow, Jane Coffin Childs Memorial Fund

2007—2010, Predoctoral Trainee, NIH Training Grant in Developmental Biology, University of Washington

Extracurricular:

  1. If not a Biology professor, I would be: pursuing something artistic.
  2. What are your hobbies? Playing soccer, running, and eating vegetarian food.
  3. What makes you happy? A sunny day in Seattle.
  4. Why did you choose to work at UW Biology? For the opportunity to work with fantastic colleagues and great students.
  5. What is your morning routine? I make breakfast for my kids, give my daughter a big hug when I drop her off at preschool, run to campus and enjoy a big mug of green tea while thinking about science.
  6. If you could choose to do anything for a day, what would it be? You mean I get to choose my superpower? Teleportation! That way I could visit the Wonders of the World without any lines.

Alejandro Rico-Guevara
Assistant Professor
Walt Halperin Endowed Professor
WRF Distinguished Investigator

Education:

Biologist - Universidad Nacional de Colombia
PhD- University of Connecticut, Miller Fellow- UC Berkeley.

Expertise:

I perform theoretical and empirical research on Behavioral Ecophysics, which I define as the study of organismal mechanisms (e.g. physiology, biomechanics) and their explicit links to biotic and abiotic interactions. My recent discoveries on nectar collection and intrasexually selected weapons revive questions on how animals balance caloric gain and expenditure, and on foraging theory in light of both exploitative and interference competition. I have focused on the most specialized vertebrate pollinators, hummingbirds, and working on such a data-rich mutualistic system opens the door to quantitative (e.g. energetics) and comparative (e.g. other nectarivores) assessments of trade-offs between energy optimality and fighting proficiency in nature.

Most fascinating research discovery:

How hummingbirds actually drink, associated adaptations in their feeding apparatus, and deviations under opposing selective pressures (e.g. bills as weapons).

Accolades (2-4 maximum):

Frank A. Pitelka Award for Excellence in Research, International Society for Behavioral Ecology. behavecol.com/awards-1

Kimberly G. Smith Outstanding Student Paper Award, Organization for Tropical Studies, 7th Annual Competition. tropicalstudies.org/research

Best Doctoral Dissertation, Greg and Mona Anderson Award, Department of Ecology and Evolutionary Biology, University of Connecticut. eeb.uconn.edu

Best Oral Presentation Award, IV Colombian Zoology Congress (selected among 2000 presentations). vccz.aczcolombia.org

Extracurricular:

  1. If not a Biology professor, I would be: Most likely I would have looked for an occupation that would have kept me in touch with nature and being outdoors: a farmer, a birdwatching guide, a park ranger, a mountain rescue responder, a scuba instructor, something like that. To some degree, I’ve tried all of the above at different stages of my life!
  2. What makes you happy? Being with my loved ones, but it doesn’t really matter what I’m doing (from hanging out in my grandma’s house for lunch, to family fencing being beaten by my in-laws!). Especially treasuring day-to-day unrepeatable moments with my wife, Kristiina, and watching our little fledglings, Sierra Annaleema and Aurora Delta, grow.
  3. Why did you choose to work at UW Biology? Because of the supportive and collaborative spirit, world-class academic excellence, its integrative approaches, the strong emphasis both in research and teaching, its interdisciplinarity, and the tight links with the Burke Museum, highlighting the importance of science communication, among many other reasons!
  4. What is your favorite childhood memory? Going on weekend trips and vacations with my parents and sisters, regardless if it was to stop on the side of the road, or going to the closest river to cook on a campfire, and all the way to when we were able to “meet the sea”. My dad is a naturalist at heart, and we have had tons of fun exploring nature together. I’m a biologist because of him!​
  5. What motivates you to work hard? A deep desire to understand the mysteries of life. Whether that means doing careful lab experiments and developing home-made devices, or spending a lot of time in the field chasing elusive behaviors; the motivation is always to go beyond the limits of our knowledge. And now supporting others to pursue similar dreams!

Adam Steinbrenner
Assistant Professor
WRF Distinguished Investigator

Education:

BS Tufts University
PhD UC Berkeley

Expertise:

My lab studies the plant immune system.  Plants defend themselves from pests and pathogens (bacteria, fungi, herbivores, etc) by detecting molecular signatures of attackers.  We are interested in receptor proteins that recognize different types of pests and how these receptors evolve in both nature and agriculture.  We hope that better understanding plant defenses will inform and inspire strategies to reduce pesticide use and develop sustainable pest control.

Most fascinating research discovery:

In my most recent position at UC San Diego, we identified a plant immune receptor that detects peptides in larval oral secretions (i.e. caterpillar spit).  Interestingly, this receptor gene is unique to the genomes of certain legume crop species such as bean and black-eyed pea, suggesting they have a unique defense strategy against attacking insects.

Accolades:

HHMI Postdoctoral Fellow 2016-2019

NSF Graduate Research Fellow 2010-2015.

Extracurricular:

  1. What is your favorite book? Team of Rivals by Doris Kearns Goodwin, Master of the Senate by Robert Caro, Anna Karenina by Leo Tolstoy
  2. What are your hobbies? Running, Hiking, Fermentation + gardening projects at home
  3. Why did you choose to work at UW Biology? UW Biology has an incredibly integrative atmosphere that fits my research style.  I try not to stay too focused on a single topic or technique, but look for links across molecular biology, genomics, and evolution/ecology.  I’m looking forward to growing my lab’s connections in the department and across campus.
  4. What is your favorite childhood memory? My mother was a landscape designer and I grew up visiting gardens and arboretums around Philadelphia.  I especially loved identifying trees and observing them across the seasons.  It is fun to see paperbark maples around Seattle – one of my old favorites from the east coast!
  5. What was your favorite subject in school? History and Political Science.  It is fascinating to learn about other societies, institutions, norms.
  6. What’s the most interesting thing you can see out of your office or kitchen window? The Space Needle view from 5th floor LSB is fantastic​
  7. What motivates you to work hard? Beyond the day to day joy of experiments, it is motivating to know that basic findings in biology can eventually translate into amazing applied breakthroughs.  In a recent example, the set of tools for CRISPR-mediated genome editing originated from observations and experiments in basic microbiology / RNA biochemistry.  The previous generation of genome editing molecules, TALENs, were originally identified from bacterial pathogens of plants that used similar proteins to manipulate their hosts.

Julie Theriot
Professor
Benjamin D. Hall Endowed Chair in Basic Life Sciences

Education: 

BS Biology and Physics, Massachusetts Institute of Technology
PhD Cell Biology, University of California, San Francisco

Expertise

The research of our group explores the mechanics and dynamics of cell self-organization and movement in a variety of cells ranging from bacteria to fish skin cells.  Our current work focuses on three areas:  1) the actin-based motility of intracellular bacterial pathogens such as Listeria monocytogenes, 2) the whole-cell crawling of epithelial cells and leukocytes, and related processes such as phagocytosis in macrophages, and 3) the dynamics of cellular organization in bacteria and diatoms.  A strength of our work is its highly interdisciplinary nature, bridging cell biology, microbiology, and biophysics.  By studying diverse questions in diverse biological systems, using both bottom-up approaches (biochemical reconstitution, single-molecule force measurements, mathematical modeling) and top-down approaches (genetic and pharmacological perturbations, quantitative video-based analysis of cell movement, shape, and mechanical coupling), we aim to develop a broad conceptual understanding of the organizational rules that give rise to large-scale cell structure and coordinated movement. 


          

Private And Central Bank Digital Currencies

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from the Atlanta Fed

-- this post authored by Larry Wall,

The Atlanta Fed recently hosted a workshop, "Financial System of the Future," which was co-sponsored by the Center for the Economic Analysis of Risk at Georgia State University. This macroblog post discusses the workshop's discussion of digital currency, including Bitcoin, Libra, and central bank digital currency (CBDC). A companion Notes from the Vault post provides some highlights from the rest of the workshop.

Read more ...


          

When the sewers get blocked: sanitation labour in urban India

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Teaser: 
On World Toilet Day, we bring to light the labour of India’s sewer workers - those who do the unclean work that a Clean India relies on.
Photo credit: Sharada Prasad

November 19th is World Toilet Day. India's massive five-year all-hands-on-deck Clean India Mission to construct latrines for all has just ended. The Government reports that 100 million additional toilets have been constructed via this campaign; these are mostly not connected to waterborne sewer systems. Just over 30% of India's urban population has access to sewers, though most city plans include elaborate plans for sewerage. Sewers are supposed to be underground and unseen, and are not supposed to need manual labour to dispose of the waste. But sewers get blocked and have to be unblocked, overflow and have to be cleaned out, break and have to be repaired. Several cities have introduced mechanisation to fix major blockages and to avoid people having to jump into the sewer system when problems arise, but sewer management remains quite a challenge.

The sewers are often densely networked, the pipes are old, the streets are narrow. Water and Sewerage Boards are just overwhelmed with the number of demands and complaints they get on a daily basis, and they can't be everywhere at once. Deaths of sewer workers in India's cities continue to occur. Sewers continue to be unblocked with makeshift equipment such as bamboo poles and iron rods; accumulated silt often needs to be cleaned out by hand or shovel. And so human labour, which in this case is inevitably Dalit labour, keeps India's sewers flowing. Technically, this is not "manual scavenging". But what is it, then? On this World Toilet Day, we bring to light the labour of India's sewer workers – those who do the unclean work that a Clean India relies on. We tell their stories through the voice of Sharada Prasad, who followed the men as they worked.

Sriramulu and Narasimhulu

August 2019. The afternoon in Hyderabad has not been tempered by the rains. I'm walking around, looking for sanitation workers. Narrow streets, dense settlements and old sewer lines are a recipe for sewer blockages. I see them: four men lifting a large slab of concrete to gain access to the drain underneath. The homeowner connected to the drain is with them, too. Once the slab is pried open, all four peer into the hole.




SPACE
THE ANTHOLOGY: 
FIVE STUDIO ALBUMS, B-SIDES, AND RARITIES (6CDs)
(Edsel Records)

Available NOW!



Space was the first – and, so far, only - “Multi-Dimensional Cinematic Technicolor Pop Band”. Hailing from Liverpool, it’d be easy to compare them to The Beatles, OMD, The La’s, The Icicle Works, Deaf School, Echo & The Bunnymen, Yachts, and any other great band that came from that small but influential part of the world.  However, Space sounds nothing like any of those artists... or anyone else for that matter. To be honest, their uniqueness bas been both a blessing and a curse. Ask Space fans what the band means to them and most of the time, each answer will be different. However, a band that always challenges itself - and musically evolves with each album release - may not be as appealing to a mass commercial audience. Space is a band ten steps ahead of the charts and it doesn’t seem that anyone has quite caught up with them yet.

Some artists are content to focus on one genre at a time but not Space. In any given song, you will find guitarist/bassist/vocalist Tommy Scott crooning a melody inspired by the ‘60s, keyboardist FrannyGriffiths exploring different eras of Electronica, guitarist/vocalist Jamie Murphy bashing out some power chords and classic Rock ‘n’ Roll-influenced riffs/licks, and solid rhythms from bassist Yorkie Palmer, and drummers Andy Parle and Leon Caffrey providing simple yet sophisticated rhythms. Surprisingly, they all remain on the same musical page and everything fits together perfectly. On the surface, Space is a slightly odd but undeniably melodic Pop band but peel away the layers and you’ll discover a band like no other. Oh, and did I mention that they have a very wicked sense of humor? Space most certainly threw out the Pop and Rock rule books and just did whatever the hell they wanted.


Space’s career is now being celebrated with a six CD box set from Edsel entitled THE ANTHOLOGYwhich contains their first five studio albums – including their previously unreleased third album LOVE YOU MORE THN FOOTBALL - as well as a slew of non-album tracks. While the band has a seemingly endless supply of remixes and single edits, this box set's bonus material wisely overlooks them and focuses on the more desirable non-album songs.  For collectors and Space novices alike, this box set is a brilliant introduction to a musical career that continues to surprise fans this very day.


SPIDERS (1996) is the band’s debut album and the only full-length released in the States. The band’s enormously popular “Female Of The Species” is their best-known track in the U.S. but the album includes plenty of gems that are just as adventurous as that fantabulous single. “Dark Clouds” is a sweeping Dance/Rock tune with Disco influences and flourishes of Flamenco added into the mix. “No One Understands” sounds like a Prog Rock tune recorded on a carousel. “Neighborhood” explores the darker side of life with such musical glee. And that is just a tip of the iceberg. One of the most engagingly eclectic albums to ever spawn some equally delightful UK hit singles.  (Disc One contains the album plus six bonus tracks)


TIN PLANET(1998) is even better. Slightly moving away from their tendency to experiment, the band turns up the melodic hook quota and offers a more refined – but still unique – approach to their music. “Avenging Angels” sounds like it could have been a James Bond theme and remains one of their finest moments. “The Ballad Of Tom Jones” is a twisted love song featuring a duet between Tommy and Cerys Matthewsfrom Catatonia. “Be There” has quirky verses but a chorus that could fit onto a ‘60s Easy Listening compilation. “The Unluckiest Man In The World” has a Madness swagger and swings like a Sinatra classic. “Bad Day’s” is quite beautiful, influenced by classic Glen Campbell but turned completely on its head with some twanging guitar and quirky lyrics. “Disco Dolly” is Punk Rock Electronica. TIN PLANET is a big step forward for the band and is a classic Pop album on almost every level. (Disc Two contains the full album plus six bonus tracks including their classic cover of “We Gotta Get Out Of This Place”)


LOVE YOU MORE THAN FOOTBALL (2000) is their legendary unreleased third album. Due to problems with the label, the album was shelved. Although a few tracks have surfaced on various ‘hits’ collections, this is the first time the full album has been released physically. Sounding like a kinder, gentler TIN PLANET,it is a shame that the album was never released because it surely would have given the band a few more hits. Mostly produced by Edwyn Collins, the album offers up a buffet of great tracks. While Franny is certainly providing plenty of atmosphere, the album is far less electronic and even more focused on classic songwriting than ever before. The previously-released “Diary Of A Wimp” is an absolute Pop classic and should have been a massive hit.  “Good Times” is yet another melodic gem, an optimistic anthem with some Hawaiian sweetener added to the mix. “Gravity” is a moody anthem with a soaring chorus. “Raymond” finds the band exploring Rockabilly. “Supersonic Jetplane” and “Despise” are delightfully delicious. “Juno 54” is a Disco-influenced instrumental with some vocals floating in and out of the mix. The only misstep is opening the album with “Everybody In The Madhouse”, a fine Techno-driven rocker that seems wildly out of place on the album. LOVE YOU MORE THAN FOOTBALL is their most accessible and rewarding album and the fact that it remained unreleased for 19 years is a travesty. A truly magnificent album that deserves to be heard. (Disc Three features the original album with no bonus tracks.)


SUBURBAN ROCK ‘N ROLL(2004) finds the band bloodied and bruised from the experience with their previous label, yet not even close to being broken. The first release after the departure of Jamie Murphy, this is an album that is a little darker than their previous releases yet they rebound with a great batch of songs. Still traveling down many musical paths at the same time, the album was produced by Stephen Lironi,who twiddled the knobs for SPIDERS. SUBURBAN ROCK ‘N ROLL isn’t SPIDERS, Part 2, though. The album is melodic, clever, and created by a band that still has plenty to say. More personal than their previous releases, this is an album that should have been heard by more people. However, working within the limitations of an independent label, the album didn’t reach as wide of an audience as their first two albums. With that being said, there are plenty of Space nuggets to be found here including “Zombies”, “Paranoid 6Teen”, “Punk Rock Funeral”, “20 Million Miles From Earth”, and the title track. Space survived the record industry and more than proved their worth on this platter. Sadly, they disappeared shortly after the album’s release. (Disc Four includes the entire album plus four bonus tracks including “Play The Songs”, one of those songs that are so good, you wonder why it didn’t make the album.)


ATTACK OF THE MUTANT 50FT KEBOB (2014) sees the return of Tommy and Franny with a new Space line-up and another set of cracking tunes. Ten years is a long time between albums but this release sounds like the natural follow-up to SUBURBAN ROCK ‘N ROLL. However, the lyrics make it seem like there may have been a few LSD trips into the world of ‘50s monster movies during their decade away. Song titles like “She’s In Love With The Boy In A Bodybag”, “Guest List To Hell”, “Day Of The Dead”, and “Attack Of The Mutant 50ft Kebab” seem to take the songs into previously uncharted territories. In reality, the band has already played with these types of lyrical images in the past but they seem to more prominent on the album. With Rock, Indie Rock, Ska, and Pop on display, this is just as wonderfully strange as their previous albums and a marvelous return for a band that still deserves your love and affection. (Disc Five contains the full album – in slightly different order than the original release – plus two bonus tracks.)


Disc Six in this box set contains additional non album tracks including cuts taken from their pre-Franny debut EP as well as songs from their online MUSIC FOR ALIENSseries. And yes, all of the tracks are must-have additions to your Space collection.
  
The Space story didn’t end there. There is a 2017 album entitled GIVE ME YOUR FUTURE that is not included in this box but has proven to be difficult to track down (I’m STILL looking for it - Spaz). Hopefully, we can look forward to more music from a band that has been overlooked here in the States. This box set should change things. Stop what you are doing and spin some Space!

Your pal,
Stephen SPAZ Schnee





          

L’actionnaire Casil Europe continue de piller les caisses de l’aéroport Toulouse-Blagnac !

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Mais que font donc M. Macron et son allié M. Moudenc ? Mardi 5 novembre, Casil Europe a donc réussi son nouveau hold-up, la répartition…

L’article L’actionnaire Casil Europe continue de piller les caisses de l’aéroport Toulouse-Blagnac ! est apparu en premier sur Archipel Citoyen.


          

Archipel Citoyen soutient le mouvement de grève dans les structures hospitalières

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Le jour où Emmanuel Macron et Jean-Luc Moudenc s’apprêtent à matérialiser leur convergence de pensée libérale, Archipel Citoyen tient à soutenir les personnels de santé…

L’article Archipel Citoyen soutient le mouvement de grève dans les structures hospitalières est apparu en premier sur Archipel Citoyen.


          

macroprolactin and prolactin?

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Forum: HORMONE REPLACEMENT THERAPY- Low Testosterone Treatment, Anti-Aging Posted By: jjsevens Post Time: 11-30-2019 at 06:39 PM
          

How To Disable Macros In MS Office Word And Excel?

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The developers in tech companies, when releasing a program design their applications in such a way that their users can get the most hassle-free computing experience. This is the reason that you find many apps to be very easy to use and include many shortcuts, which make their use worthwhile. These shortcuts are called macros, […]

The post How To Disable Macros In MS Office Word And Excel? appeared first on Silicophilic.


          

Substituted Co(II) and Cu(II) metallophthalocyanines from new Schiff base containing pyrrole units: Synthesis, characterization and investigation of photocatalytic activity on 2,3-dichlorophenol oxidation (October, 10.1007/S10847-019-00949-Z, 2019)

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Title: Substituted Co(II) and Cu(II) metallophthalocyanines from new Schiff base containing pyrrole units: Synthesis, characterization and investigation of photocatalytic activity on 2,3-dichlorophenol oxidation (October, 10.1007/S10847-019-00949-Z, 2019)
Author(s): Aktas Kamiloglu, Ayse; Saka, Ece Tugba; Acar, Irfan
Source: JOURNAL OF INCLUSION PHENOMENA AND MACROCYCLIC CHEMISTRY, NOV 13 2019
Document Type: Correction; Early Access
          

We didn mistrust Kennedy the way we did Nixon

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28 trombonists play 'bohemian rhapsody

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Vì sao các tổng thống Pháp không di chuyển bằng tàu tốc hành TGV?

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Năm 2016, truyền thông Pháp phát đi hình ảnh Emmanuel Macron, khi ấy là ứng viên tranh cử tổng thống, dùng tầu siêu tốc TGV để di chuyển. Hình ảnh này sẽ không bao giờ được tái hiện trong suốt nhiệm kỳ của ông. Đơn giản là vì tất cả các đời tổng thống Pháp chẳng bao giờ hoặc gần như không bao giờ dùng tầu TGV. Nhật báo kinh tế Les Echos giải thích.
          

Tổng thống Thổ Nhĩ Kỳ : Nguyên thủ Pháp « chết não, nghiệp dư »

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Tổng thống Thổ Nhĩ Kỳ Recep Tayyip Erdogan hôm qua 29/11/2019 đã chỉ trích thô bạo đồng nhiệm Pháp Emmanuel Macron, cho rằng nguyên thủ Pháp đang « trong tình trạng chết não ».
          

Dzień otwarty_05.12.2019 r.

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W czwartek, 05.12.2019 r. zapraszamy rodziców i opiekunów na spotkania z wychowawcami i nauczycielami.

godz. 16.00 klasa "0"C

godz. 17.00 klasy IV - VIII oraz "0"B
godz. 18.00 klasy I - III

Na stołówce w godz. 16.45 – 18.45 będzie dyżur firmy PrimaSort. Chętne osoby zapraszamy do rozmów z przedstawicielami ajenta.

Na parterze swe miejsce będzie miało stoisko kiermaszu świątecznego zorganizowane we współpracy z Radą Rodziców. Przypominamy, że całkowity dochód rozpocznie zdobywanie środków na rzecz WOŚP. Czekamy na Was !

Na parterze znajdzie się też punkt Rady Rodziców - prezydium zaprasza do współpracy, przypomina o dobrowolnych składkach i podkreśla , że zebrane fundusze służą tylko i wyłącznie dla naszych dzieci.

Przydział sal na spotkania z wychowawcami


          

Progress is slow.....

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Following on from my single bowl cosy last week, my hand permitted me to make three more on Sunday. Sewing was not an issue, but cutting was! The pressure required of my left hand, to hold the cutting ruler in place was uncomfortable after a few cuts. 
I think though if I am careful I might be able to get back to making up the blocks for my down in the garden quilt. LOL No promises, you know how the mood can change, for no apparent reason. LOL
Once I had given up in my wee room I returned to the sitting room and decided to try a little crochet. I didn't want to push my wrist and thumb, so only worked two very slow rows, but progress was made and I have done a little more each day since. Although I'm taking it very slowly, I am enjoying my crochet again.
 While I was sewing and crocheting on Sunday, Tony was fishing with his dad and brother. They stayed out longer than usual as the fishing was slow, but did eventually come home with a good catch. 
They had their usual haul of Blue cod
 and sea perch or Jock Stewart as the skipper calls them.
Tony caught a tarakihi 
and a species new to him known as a leather jacket.
(All these pictures were taken off the WWW and are not mine!)
That's all my news for today. Later, after a few chores I may crochet, or I may continue with my blue stitchery.
First a trip into town to purchase felt for the back of my stitched owl. 





          

Delevoye, chargé par Macron de la réforme des retraites, annonce l’importation de 50 millions de migrants musulmans en Europe pour sauver les pensions des Boomers

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Vous devez lire ça si vous voulez survivre
          

La City pronostica que en 2020 el dólar podría superar los $100 pero perderá contra la inflación

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Los principales bancos creen que el primer año de Alberto Fernández mantendrá la volatilidad macro, pero con un dólar que empezará a funcionar como "ancla"
          

Honor Launches View30 5G Smartphones: 6.57-Inch, Kirin 990, 40MP

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Honor has introduced its View30-series smartphones that bring the latest mobile technologies its parent company Huawei has to offer, including the top-of-the-range SoC, a triple-module camera, as well as 5G connectivity, in a rather democratically priced package. Honor’s V30 family consists of two base modes — the V30 and the V30 Pro — that are set to be available in various RAM/storage configurations.

Traditionally aimed at younger consumers, Honor’s phones feature a body with eye catching paint job that promises to be appreciated by the target audience. In case of the View30 and View30 Pro, we are dealing with the so-called Aurora nano texture paint as well as Ocean Blue, Galaxy Black, Icelandic Frost, Sunrise Orange colors. Both handsets come with a 6.57-inch FullView IPS display featuring a 2400x1080 resolution and a punch hole for two of its selfie cameras, which we will discuss later.

Honor’s View30 family contains two base models that have generally the same functionality, yet are slightly different in terms of internal hardware. The V30 is based on HiSilicon’s Kirin 990 SoC accompanied by the Balong 5000 5G modem. By contrast, the V30 Pro version features HiSilicon’s Kirin 990 5G application processor with an integrated 5G modem.

Without any doubts, 5G support is the key selling feature of the new smartphones, yet it is implemented a different way in case of the View30 and the View 30 Pro models - the choice of producing essentially the same device, both with 5G capability and also with very similar SoCs is a quite odd product development choice.

The regular V30 sports 6 GB or 8 GB of RAM, 128 GB of storage, while the V30 Pro is paired with 8 GB of RAM and 128 GB or 256 GB of storage. 

Moving on to imaging capabilities of the smartphones, the Honor View30-series handsets are equipped with a triple-module rear cameras, comprising of a 40 MP Sony IMX600 main module with OIS, a 12 MP ultra-wide camera, and a 3x optical zoom 8MP zoom module. Both models also have a 32 MP selfie camera which is complemented by an 8 MP wide-angle module. As we would expect from late 2019 cameras, they come with ‘AI-enhanced’ software designed to improve quality and simplify usage.

Speaking of software, it is necessary to mention that Honor's View30 Series handsets use Google's Android 10 with the company's Magic UI 3.0.1, but without Google Play and other Google services.

Rounding out the package, the new handsets naturally feature 4G/LTE, Wi-Fi 5, Bluetooth 5.1, navigation, a USB 2.0 Type-C port, a side-mounted fingerprint reader, a 4,100 mAh battery that can be charged using a wired or wireless charger supporting SuperCharge, wireless reverse charging support. 

Since Honor brand does not produce ultra-high-end devices that would compete against flagship smartphones from Huawei, they a few of the more premium features. The View 30 handsets thus are not dust and water resistant, they do not feature a Nano Memory slot, and, as mentioned above, are not equipped with DCI-P3-capable OLED displays, instead relying on a more traditional IPS LCD screen.

Honor View 30 Series
  View30 View30 Pro
SoC HiSilicon Kirin 990
2x Cortex-A76 @ 2.86 GHz
2x Cortex-A76 @ 2.09 GHz
4x Cortex-A55 @ 1.86 GHz

+ Balong 5000 5G modem
HiSilicon Kirin 990 5G
2x Cortex-A76 @ 2.86 GHz
2x Cortex-A76 @ 2.36 GHz
4x Cortex-A55 @ 1.95 GHz

 
GPU Mali G76MP16 @ 600MHz Mali G76MP16 @ 600MHz
DRAM 6 GB or 8 GB LPDDR4X 8 GB LPDDR4X
  128 GB 128 GB or 256 GB
Display 6.57" FullView IPS LCD
2340 x 1080 (19.5:9)
96% NTSC
400 PPI
Size Height 162.7 mm
Width 75.8 mm
Depth 8.9 mm
Weight 213 grams
Battery Capacity 4100 mAh (Typical)
40 W charging
Wireless Charging 27 W charging + reverse charging
Rear Cameras
Main 40 MP Sony IMX600
f/1.6 aperture w/OIS

Laser Focus Sensor
Telephoto 8 MP
f/2.4 aperture

3x optical zoom
Wide 12 MP 1.4μm pixels
f/2.2 aperture w/OIS

109° Super-wide Angle

"Pro-grade videography", Macro images
Front Camera 32 MP selfie camera
f/2.0 aperture

AIS Super Night mode
Bokeh effect

8MP wide angle selfie camera
f/2.2 aperture

105°Super-wide Angle
I/O USB 2.0 Type-C
Wireless (local) 802.11ac (Wi-Fi 5),
Bluetooth 5.1
Cellular 5G NR: N1/N3/N41/N77/N78/N79
4G TD-LTE (Type C):B34/B38/B39/B40/B41 (2515~2675MHz)
4G FDD LTE: B1/B2/B3/B4/B5/B7/B8/B12/B17/B18/B19/B26
3G WCDMA: B1/B2/B4/B5/B6/B8/B19
CDMA (Primary or secondary cards): BC0 (only supports China Telecom in Mainland China and Macao)
2G GSM: B2/B3/B5/B8
Splash, Water, Dust Resistance -
Dual-SIM 2x nano-SIM
Launch OS Android 10 with Magic UI 3.0.1

without Google services
Launch Price 6 GB + 128 GB: CNY 3,299
($405 w/o VAT)
8 GB + 128 GB: CNY 3,899
($479 w/o VAT)

Characteristically for Honor and its parent company these days, the View30 and View30 Pro will initially be available only in China. The price of the former will start at CNY 3,299 ($405 w/o VAT), whereas the price of the latter will begin at CNY 3,899 ($479 w/o VAT). Given positioning of the phones, it does not really make sense to convert their prices to other currencies as they will be priced in accordance with local market realities

Related Reading:

Source: Honor


          

[Solved] Get parent name when printing child menu items

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Hello,

I am trying to write a twig file to print menu (main--menu.html.twig). My menu and sub-menu links are showing, but I need to get the name of the menu item after I get into

{% macro submenu_links(items, attributes, menu_level) %}
  {% import _self as menus %}

Say I have Menu structure like 

-Cars

-- BMW

-- Toyota

- Bikes

-- Harley

-- Yamaha

Now when I get into Submenu of cars using the code above in main--menu.html.twig, I want my menu item to print like "Toyota (Car)". So how can I get the name of the parent Menu item (car) when printing subMenu item (Toyota) ?

Drupal version: 

          

Trump a NATO. Smrť? Šándor veľa naznačil. A krútil hlavou nad trestom pre Rusko

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Francúzsky prezident Emmanuel Macron vyhlásil o NATO, že sa nachádza v stave „mozgovej smrti“. Bezpečnostný poradca Andor Šándor si nie je istý, či už nenastal čas NATO pochovať, osobne by si to vraj neprial, ale isté slabiny v Aliancii vidí. NATO podľa jeho názoru prestalo plniť svoje tri základné ciele a navyše jeden z jeho členov – Turecko – porušil princípy, na ktorých Severoatlantická aliancia stojí. Všetko s tichým súhlasom prezidenta USA Donalda Trumpa.
          

Central Bank Governor Complains To The Economist Over Exclusion Of Hungary’s Macroeconomic Data

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National Bank of Hungary (MNB) governor György Matolcsy has written a letter to The Economist protesting the exclusion of Hungary from a list of macroeconomic indicators the newspaper regularly publishes, the central bank said on Monday. Matolcsy complained in the letter that The Economist has not published selected macroeconomic indicators from Hungary since April 25, […]

The post Central Bank Governor Complains To The Economist Over Exclusion Of Hungary’s Macroeconomic Data appeared first on Hungary Today.


          

Le règne du style « En même temps » à l'Élysée

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Si Emmanuel Macron cherche encore son Jack Lang cote culture, cote arts decoratifs, il n'a pas encore trouve son Pierre Paulin. Le style Macron existe-t-il ?
          

"Agyhalott" - durván beszólt Erdogan a francia elnöknek

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Recep Tayyip Erdogan török elnök pénteken Isztambulban - néhány nappal a decemberi NATO-csúcsértekezlet előtt, amellyel a katonai szövetség megalapításának 70. évfordulóját is tervezik ünnepelni - arra szólította fel francia hivatali kollégáját, Emmanuel Macront, hogy vizsgáltassa ki magát, nem agyhalott-e, miután a francia elnök november elején a
          

2019-10412 - Stagiaire - Chargé(e) Etudes Statistiques - Data - Digital H/F

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Métier : Systèmes d'informations/Matériels, Télécom & Réseaux
Type de contrat : Convention de stage
Description du poste :
Rattaché(e) au service Maintenance en Ligne, et sous la responsabilité de votre maître de stage, vos missions consisteront à : Créer les requêtes sous SAP/BI4 nécessaires au suivi et à l’organisation de notre activité Mettre en place, suivre, analyser et diffuser des indicateurs de performances ponctuels ou permanents Enrichir notre portail Intranet Mettre en place des outils de suivi d’activité (Commandes hors magasin Air France, Cahier de consignes digital…)

Vous êtes étudiant(e) en 4eme ou 5eme année d’Ecole d’ingénieur en informatique et vous recherchez un stage d’une durée de 6 mois dans un environnement dynamique au cœur de la maintenance en ligne de CDG. Vous êtes curieux(se), dynamique, imaginatif(ve) et aimez travailler dans un cadre pluridisciplinaire   Vous avez de bonnes capacités d’écoute, d’analyse et de synthèse   Vous êtes méthodique, rigoureux(se) et possédez de bonnes qualités relationnelles Vous maîtrisez SAP/BI4, Microsoft OFFICE et outils numériques associés ainsi qu’Excel, les macro VBA et les bases de données. Vous avez un bon niveau d'anglais (lu, parlé, écrit)   Conformément aux engagements pris par Air France dans son accord 2018-2020 en faveur de l’emploi des personnes en situation de handicap, nos contrats sont ouverts à tous.
Site : ROISSY CHARLES DE GAULLE
Niveau d'études min. requis : Bac + 4 / 2ème année grande école
Langue / Niveau :
Anglais : 3 - Confirmé

          

BoG introduces new denominations

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The Bank of Ghana (BoG) has introduced two new higher denominations of the Ghana notes and a coin to complement the existing currencies in circulation.

The new denominations are the hundred and two hundred Ghana cedi notes and a two cedis coin that are expected to be in circulation from Monday, December 2, 2019.

Features

The size of the new GH¢100 is 157mm x 80mm and is predominantly grey in colour with turquoise highlights. The main image at the back of the GH¢100 banknote is Ghana’s Parliament Chamber with the secondary image of the Parliament building.

The GH¢ 200 is predominantly terracotta with red grey highlights with the seat of Government, the Jubilee House, as the main image at the back.

The GH¢2 coin has the image of the Ghana Coat of Arms on the front with the Jubilee House at the back, both embossed on silver with gold around it like a fence.

Convenience and efficiency
Speaking at the launch of the currencies, Governor of the Bank of Ghana, Dr Ernest Addison, said the introduction of the new denominations was to complement the existing series to ensure customer convenience and bring about efficiency in the printing of currency to generate savings for the country.

Dr Addison said high levels on inflation and currency depreciation in the past had eroded some of the gains of the redenomination in 2007.

Deadweight burden

Dr Addision said the deadweight burden reflected in high transaction cost had re-emerged. This set of high denominations will address the increased transaction cost in a high valued transactions in a cash-based economy.

“These new higher value denominations will only restore partially the dollar value of the higher denomination of GH¢200 to about US$40”.

“This may not be quite close to levels in 2007, but high enough to significantly reduce the deadweight burden and high transaction cost in making high-valued purchases in a cash-based economy like Ghana,” Dr Addison said.

“This is why we continue to pay attention to enhancements in the structure, security features and management of cash within the economy. This will stay with us for some time”, he added.

Currency reforms

As part of the currency reforms, the central bank in May this year upgraded some of the currency to enhance the security features of the banknotes in the context of an evolving technological landscape.

Analysts have urged the central bank to be cautious on the circulation of the higher denominated banknotes.

The Governor said it was normal practice in all jurisdictions for central banks to periodically review the structure of their currencies with the view to ensuring that they were aligned with macroeconomic conditions and demand.

He cautioned that the introduction of the high value is not a shift away from the country’s policy of pursuing a cashless society and promoting the use of electronic modes of payments.

“While vigorously pursuing financial inclusion by accelerating the migration to e-payment platforms, we are also mindful of the relevance of cash in our day-to-day dealings. Undeniably, cash still remains the preferred medium of payment by the large informal sector in the country”, he said.

High depreciation

In 2007, when the country redenominated its currency, GH¢50 was equivalent to $50 but 12 years on, the same GH¢50 is now worth only $9.

It has depreciated by more than 80 per cent.

In a bid to restore some of the lost parity to the dollar, the central bank has introduced the highest banknote of GH¢200, which is four times the previous highest denomination. But not even a fourfold increase in the highest denomination could restore the parity it had in 2007.

Not solution to depreciation

A Senior Economist at Databank, Mr Courage Martey, agrees that the structure of the banknote should align with the needs of the people who use it for their daily transactions, but cautioned that the higher denominations should be limited in supply and in circulation as the introduction of higher denominations will not tackle the fundamental problems of the persistent high inflation and the perennial currency depreciation.

“As long as these fundamental issues are not addressed, we could be coming back to introduce yet another set of higher denominations in the next decade”, he said.

Mr Martey suggested to the country’s economic managers to keep an eye on low inflation and a stable Ghana Cedi.
“If we don't achieve these fundamental correction in the economic indicators, the real value of these new higher denominations will be eroded and we will have to come back to introduce even higher notes”, he said.


          

BoG maintains policy rate at 16%

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For the fourth time this year, the Monetary Policy Committee of the Bank of Ghana (BoG) has maintained the policy rate at 16 per cent.

The decision to maintain the rate was as a result of some threats to both  inflation outlook and economic growth.

This was announced by the Governor of the Bank of Ghana (BoG), Dr Ernest Addison, while addressing the media after the 91st Monetary Policy Committee (MPC) meeting in Accra.

 He added that the threats to inflation were broadly balanced hence the need to maintain the policy rate at 16 per cent.

He said the committee noted the synchronized growth slowdown across advanced economies and its potential spillover effects on emerging markets and developing countries.

“In addition to subdued inflation, recent assessments indicate that the global economy is in a low growth, low interest rate environment. Major central banks have, therefore, shifted towards accommodative monetary policy stance which will likely persist until signs of growth emergence or inflation pick-up becomes evident.

“These developments have triggered favourable global financing conditions as investors search for yield in emerging markets and frontier economies with strong fundamentals, underscoring the need to further consolidate the macroeconomic gains and to position the economy to benefit from the favourable external financing conditions,” he stated.

Inflation

Mr Addison noted that the three readings of inflation since the release of the rebased Consumer Price Index by the Ghana Statistical Service showed that inflation had remained below its central path of eight per cent.

He said headline inflation declined from 7.8 per cent in August 2019 to 7.6 per cent in September, and had since inched up to 7.7 per cent in October on the back of the recent upward adjustment in administrative prices of electricity and water.

Looking ahead, he said, inflation was projected to stay within the medium-term target of 8±2 per cent over the forecast horizon.

Commodities

On the international commodities market, Dr Addison said data showed that crude oil prices fell by 3.8 per cent on a year-to-date basis to close at an average of US$59.8 per barrel for October 2019.

He said the decline was on account of investor concerns about the unrelenting US-China trade tensions and continued build-up in US crude inventories.

He noted that gold prices also slipped marginally to $1,490.9 per fine ounce after trading above the $1,500 per ounce for two successive months on the back of dovish monetary policy stance by major central banks.

“On a year-to-date basis, gold prices gained 18.9 per cent. The average price of cocoa increased by 11.2 per cent to settle at $2,475 per tonne in October 2019. This was mainly supported by increased third quarter grinding data which serves as proxy for demand,” he stated.

Trade account

He said the favourable commodity price developments, together with increased production volumes, impacted positively on the trade account.

In the period January to September 2019, exports stood at $11.7 billion  while imports started recovering, reaching $10.0 billion.

These developments resulted in a further improvement in the trade surplus which stood at $1.68 billion, compared with $1.56 billion in the same period in 2018.

Current transfers improved, resulting in a further lowering of the current account deficit to $829.5 million, compared to a deficit of $1.0 billion  in the same period of 2018.

Gross International Reserves (GIR) increased by $1.67 billion to$8.70 billion as of November 15, 2019, providing cover for 4.2 months of imports. This compares with the end-December 2018 position of US$7.02 billion which is equivalent to 3.6 months of import cover.


          

La plus grosse bulle obligataire de tous les temps vient d’atteindre un nouveau sommet historique à 56 540 milliards $ !!

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La folie monétaire se poursuit ! La plus grosse bulle obligataire en 800 ans d’histoire continue d’enfler inexorablement. Rappelez-vous qu’en 2017, le marché obligataire mondial avait progressé de 5200 milliards de dollars, soit le PIB du Japon. En ayant gagné près de 6088 milliards de dollars depuis le début de l’année 2019, la capitalisation obligataire mondiale vient d’atteindre un nouveau sommet historique à 56 540 milliards de dollars. Cette progression suit la forte baisse des indicateurs avancés de la conjoncture économique. En outre, face à la dégradation macroéconomique mondiale, Draghi et Powell soutiennent artificiellement l’économie à base de dette, encore et toujours. Vous pensez vraiment qu’on puisse régler un problème d’endettement en émettant davantage de dettes ? Les banquiers centraux sont-ils devenus fous ? Le crash arrivera à un moment où ça va être le plus violent !! Selon Alan Greenspan, la plus grande bulle obligataire de tous les temps est sur le point d’éclater ! Pento: « L’éclatement de cette énorme bulle obligataire aura des conséquences dévastatrices » Source: Holger Zschaepitz A l’attention des lecteurs du site BusinessBourse Nous sommes à la veille d’un tournant majeur dans l’économie mondiale. Le moment est venu d’acheter de l’Or avant qu’il ne [...]

The post La plus grosse bulle obligataire de tous les temps vient d’atteindre un nouveau sommet historique à 56 540 milliards $ !! appeared first on BusinessBourse.


          

Presidente da República e Comandante Supremo das Forças Armadas apresenta condolências ao seu homólogo francês

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Ao tomar conhecimento do trágico acidente que vitimou ontem treze militares franceses no Mali, pertencentes à Operação Barkhane, que visa combater grupos extremistas naquela região, o Presidente da República e Comandante Supremo das Forças Armadas apresentou condolências, em nome de todos os Portugueses, ao Presidente da República Francesa, Emmanuel Macron, expressando a sua solidariedade para com os familiares e amigos destes militares do Exército Francês.


26.11.2019
          

Musicvideo Background Video

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ATMODEPTH posted a photo:

Musicvideo Background Video

www.youtube.com/channel/UCE1NXclMkHA8G1TBtI6d9kw Musicvideo background video is a video as background. Madewith CryengineV. #Musicvideo, #Video, #Art ___ [SECTION] ATMODEPTH About Part ___ Some Information About ATMODEPTH: ATMODEPTH is an indie game developer, photographer, artist and blogger. Main creations are Indie games, photography, videos, music, art, tutorials and blogs. ATMODEPTH work focuses on creativity, art, research, science fiction, fantasy and entertainment. The videos cover gaming and tech solutions along with some weird funny things. ATMODEPTH is the creator of the game ATMOTECH, an action-adventure-jump-and-run-game with open world and roll play elements which was achieved with Cryengine and got released as early access on Steam in 2018. ATMODEPTH photography covers nature, landscapes, graphic and abstract elements as much as simple macro motives and illustrations. The blogs feature multiple subjects. Everybody can stay in touch via different websites, networks and blogs. 1.) Contact: bit.ly/2ZaZSUX www.youtube.com/channel/UCE1NXclMkHA8G1TBtI6d9kw twitter.com/ATMODEPTH 2.) Legal: This Page Might Include Ads. ATMODEPTH Gives No Warranties Or Professional Advice. In No Event Shall ATMODEPTH Be Liable For Any Damages Arising From The Use Of This Content. ATMODEPTH Takes No Responsibility For Any Content. All Rights Reserved. 3.) Donate: bit.ly/30dXlXt bit.ly/2ZaZTZ1 bit.ly/30bZ8w1 Signature: #indiegamedev, #photography, #videos, #music, #art, #tutorials, #blogging #gaming, #actionadventure, #scifi, #fantasy, #creativity, #sounds, #education, #entertainment, #fun bit.ly/2ZiW4Bm www.youtube.com/channel/UCE1NXclMkHA8G1TBtI6d9kw twitter.com/ATMODEPTH


          

ATTENTI A PARLARE DI “NUOVA IRI”

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Radio Articolo Uno, 29 novembre 2019 – Si evoca spesso il ritorno ad una nuova IRI, un tema di grande rilevanza che si fa strada man mano che le crisi industriali si intensificano. Bisognerebbe però ricordare che l’esperienza delle partecipazioni statali di massa è legata a una fase storica caratterizzata da assetti macroeconomici e finanziari […]
          

La Cumbre del Clima dejará 148 M € en Madrid

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La Puerta de Alcalá, el palacio y la fuente de Cibeles se iluminarán de verde todas las tardes y noches desde la inauguración, este lunes, de la Cumbre del Clima, que se prevé que deje unos ingresos de 148 millones de euros en la ciudad, hasta que termine esta gran cita internacional de la Organización de Naciones Unidas (ONU). Como informó HOSTELTUR en La Cumbre del Clima, un desafío de 25.000 congresistas para Ifema, el encuentro prevé la participación de 25.000 personas de casi 200 países.


La campaña publicitaria en torno al evento ocupa diversos soportes exteriores con los logos y lemas de la cumbre desplegados en 200 marquesinas y más de 1.200 banderolas, y con carteles de las actividades de Madrid Green Capital, según explica el Ayuntamiento de la capital en una nota.

Además, se han tematizado para la ocasión los puntos de información turística, en los que se distribuye la Guía de Madrid en formato digital y en tres idiomas, inglés, francés y español.

La Cumbre será un reto organizativo y de seguridad para Madrid. Foto: Efe.

En esta iniciativa se han implicado algunas de las compañías integradas en el Foro de Empresas por Madrid, la plataforma de colaboración público-privada liderada por el Consistorio. Es el caso de Mahou o de Telefónica, empresa esta última que, también este lunes, vestirá su sede de verde con iluminación led.

Cada uno de los viajeros gastará 265 euros generando un impacto directo de 73 millones, a los que habría que sumar los ingresos derivados del alquiler de instalaciones y los indirectos, hasta un cómputo total de 148 millones.

La Cumbre del Clima de la ONU "encumbrará a Madrid como destino de turismo de negocios, como un gran centro de organización de congresos y convenciones, y supone un refrendo en la capacidad de Madrid de organizar un macroevento internacional", añade el Ayuntamiento.

Ifema destina a la cumbre seis pabellones completos y 100.000 metros cuadrados de superficie, cifras que suponen la mitad de la extensión del recinto y un 25 % más de lo previsto.


          

Apps para viajar por la España vacía, hoteles circulares, redes sociales...

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Estas son las noticias de Innovación que debe asegurarse de conocer antes de empezar la nueva semana. Feliz domingo.


El Patrimonio de la Humanidad en España, bajo la lupa del smart data

España cuenta con 50 sitios declarados Patrimonio de la Humanidad por la UNESCO y su reputación online media alcanza una nota de 9,23 puntos sobre 10, según reflejan las opiniones compartidas en la red por 1,2 millones de viajeros. Sin embargo, las páginas web oficiales de dichos destinos "tienen en general un posicionamiento discreto".

Redes sociales: herramientas sexys que no lo dicen ni lo dan todo

Responsables de marketing de tres cadenas hoteleras y una compañía aérea española coincidieron que hoy las redes sociales son herramientas irremplazables si se quiere un contacto real con los clientes. Son “tremendamente atractivas” porque permiten obtener datos, transformarlos en personalización y generar retorno; sin embargo “no dan toda la información” y se vuelve indispensable recurrir a intermediarios.

Qué puede aprender el turismo de la innovación en otros sectores

Los expertos coinciden en que, en líneas generales, el turismo va por detrás de otros sectores en su proceso de digitalización. De ahí el interés por escuchar a los responsables de grandes empresas financieras, energéticas y sanitarias, entre otras, reunidas por Forbes para compartir su experiencia.

Tecnología para mejorar la experiencia turística de las familias

Echar mano de consejos de la población local para elegir mejor entre diferentes opciones y ahorrarse así un dinero; encontrar fácilmente actividades para niños con información actualizada de horarios y precios; saber qué farmacias o parques infantiles existen cercan... Cuando una familia viaja, las incertidumbres y el gasto pueden llegar a dispararse. Y con el fin de mejorar la experiencia del turismo familiar, se ha puesto en marcha un proyecto tecnológico que se desarrollará en los destinos de Costa Daurada y Terres de l'Ebre, en Cataluña.

Una app de viajes en caravana para ayudar a la España vacía, premio CETT

Una app que impulsa los viajes en caravana bajo el lema "Descubre micropueblos, vive macroexperiencias" ha sido la ganadora en la quincena edición de los Premios Emprendedores a la innovación turística. Dichos galardones son concedidos por la facultad de Turismo CETT, adscrita en la Universidad de Barcelona.

El Gran Meliá Palacio de Isora está considerado como uno de los hoteles más sostenibles en España.

Los hoteles más circulares del mundo… y algunos son españoles

El turismo en general, y más concretamente el sector hotelero, está cada vez más concienciado de la necesidad de aplicar los principios de la economía circular a su actividad para ser sostenible en el tiempo y por ende más competitivo. También porque los clientes son asimismo conscientes de que el mundo no puede continuar con una economía lineal como hasta ahora, por lo que demandan cada vez más un comportamiento más responsable por parte de la industria. Una industria en la que encontramos algunos ejemplos de buenas prácticas a seguir, enumerados por Manuel Aguirre, socio fundador de la consultora Sostinendo, en las jornadas del Seminario INTO que se están celebrando esta semana en Palma.


          

Dicas para quem vai fazer um dia a Estrada Nacional 2

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Após já muitas semanas, e antes que a memória comece a desvanecer, seguem algumas dicas da recente experiência para ajudar quem um dia queira fazer a aventura da EN2 de bicicleta.


1. Sozinho ou em grupo?

Na minha opinião fazer a EN2 sozinho não será uma experiência agradável, a não ser que se queira fazer numa de isolamento e introspecção pessoal.

A par já será interessante para ter uma companhia, repartir os custos e até partilhar a experiência no seu todo.

Nós fizémos num grupinho de 3 e acho que foi o ideal, pois acaba por ser uma boa convivência social de apoio, confraternização e até a repartição de custos é mais simples.

Se calhar mais que 3 já seria logisticamente mais complicado gerir ritmos, vontades e alojamento... a não ser que houvesse um grande alinhamento prévio nesse grupo.

2. Duração

Cada pessoa ou grupo terá o seu ritmo, que dependerá muito da forma física e calendário disponível, pelo que o meu conselho é baseado na experiência recente desta nossa viagem.

Nós fizémos em 6 dias a rolar, mas dado que para chegar ao ponto de partida em Chaves tivémos de tirar outro dia para essa viagem acaba por ser 7 dias para este percurso.

O que aconselho, partindo de Lisboa, será que quem queira e possa tire apenas a tarde de sexta de "féria" e apanhe o autocarro para Chaves de forma a começar a viagem no Sábado seguinte e assim fazer a viagem em 8 a 9 dias a rolar, de Sábado a Domingo.

Desta forma poderão fazer a viagem de forma mais vagarosa e apreciando os cantos e recantos do interior de Portugal, fazendo até distâncias mais curtas para quem não esteja em tão boa forma física.

E assim apenas necessitar de 5 dias e meio úteis de folga do trabalho.

3. Transportes

Lisboa > Chaves : Autocarro

Nós fomos os 3 de Lisboa para Chaves pela Rede de Expressos.

Recentemente a Rede Expressos passou a cobrar pelo transporte de bicicletas (e outros equipamentos desportivos como pranchas de Surf) e eu acho isso muito bem!

Antes ficava um pouco ao critério do motoristas e de haver muita ou pouca bagagem normal se a bicicleta podia ou não embarcar no dito autocarro. Agora assim é um custo de um serviço pelo que tem meessssmo de levar a bicicleta como bagagem. O custo do bilhete da bicicleta são apenas 5€!

Convém comprar com antecedência para garantir o lugar para a bicicleta...


"Quero fazer uma viagem com a Rede Expressos/Renex e tenho uma bicicleta para transportar. Posso viajar?
Sim, pode. O transporte de bicicletas ou pranchas de surf implica um acréscimo no preço do bilhete de 5 euros. Apenas é permitido o transporte mediante a compra prévia, exclusivamente online, mediante o pagamento da referida taxa. Dada a limitação de espaço, é permitido um total de quatro unidades, entre bicicletas e pranchas de surf, por veículo. Estas devem estar em condições de viajar sem provocar danos nas restantes bagagens ou volumes, sendo obrigatório desmontar a roda da frente, colocando-a sobre o quadro e estando o respetivo conjunto embalado numa caixa ou bolsa preparada para o transporte. Se não houver espaço para mais bicicletas no horário escolhido, a célula de seleção de viagem com bicicleta não estará disponível. Depois de adquirir o bilhete, o passageiro deve apresentar-se para embarque, com a sua bicicleta/prancha de surf, com uma antecedência mínima de 15 minutos antes da saída. Outras bagagens especiais: serão aplicáveis os mesmos preços e condições a todos aqueles equipamentos e acessórios de desporto e/ou lazer equiparáveis, similares aos descritos anteriormente e que, pelas suas dimensões e/ou características, devam ser transportados no porão do autocarro. Estas bagagens devem estar em condições de viajar sem provocar danos nas restantes bagagens ou volumes, sendo obrigatório o respetivo embalamento para o transporte."

https://www.rede-expressos.pt/faq

Faro > Lisboa : Comboio Intercidades

No nosso último dia de viagem a rolar chegámos a Faro com alguma pressa para ainda conseguirmos o regresso no Domingo, pois como país civilizado temos muito poucos comboios a ligar pontos relevantes do país.

Os comboios intercidades permitem o transporte de bicicletas, sem desmontar nem embalar, num máximo de duas por cada carruagem, o que num dia como domingo estávamos apreensivos se iriamos ou não conseguir embarcar. Felizmente chegámos a tempo e horas à estação e lá comprámos as passagens para o regresso a Lisboa. Não se paga para transportar a bicicleta, mas é preciso na compra do bilhete indicar que se pretende levar uma bicicleta para reservar o espaço da mesma.


"O transporte de bicicletas é gratuito.

Comboios Intercidades das Linhas do Norte (Lisboa – Porto / Guimarães / Braga / Viana do Castelo), Beira Alta, Beira Baixa, Alentejo (Lisboa Oriente / Évora) e Sul

As carruagens de 2ª classe destes comboios Intercidades possuem suportes específicos para o transporte de bicicletas tradicionais, permitindo o transporte de 2 bicicletas por carruagem.

Condições particulares:

  • Apenas é permitido o transporte de uma bicicleta tradicional por passageiro;
  • O peso da bicicleta deve ser igual ou inferior a 15 kg;
  • O transporte de bicicletas está condicionado à disponibilidade dos lugares destinados a esse efeito - lugares 15 e 17 das carruagens de 2.ª classe nos comboios Intercidades da Linha do Norte (Lisboa-Porto/Guimarães/Braga/Viana do Castelo) e lugares 12 e 18 das carruagens de 2ª classe nos comboios das Linhas da Beira Alta, Beira Baixa, Alentejo (Lisboa Oriente/Évora) e Sul. No caso destes lugares já não se encontrarem disponíveis, apenas é possível transportar bicicletas se as mesmas se encontrarem dobradas ou desmontadas e acondicionadas no espaço disponível para bagagem, não sendo admitida mais do que uma bicicleta por passageiro.
  • Os suportes existentes nas carruagens não possuem cadeados."
https://www.cp.pt/passageiros/pt/informacao-cliente/informacao-util/transporte-bicicletas


4. Alojamento

Acampar versus Hóteis/Pensões/Alojamento Local

Desde o início que este grupo de jovens quarentões decidiu que não se queriam sujeitar a essas delícias e maravilhas do campismo, há quem goste e nada contra, mas não queriamos levar toda essa parafernália a pesar na bicicleta e gastar tempo a montar e desmontar a tenda todos os dias.
#CicloturismoEmHotéis era o mote... Traveling light :)

Marcações e reservas

Nesta aventura, à excepção do alojamento em Chaves que previamente reservamos online pelo Booking, todos os remanescentes alojamentos foram sendo marcados no próprio dia à medida que nos iamos aproximando da localidade que consoante o nosso ritmo definíamos como objetivo de meta.

Obviamente dado o tempo limitado que tinhamos para a travessia sabiamos mais ou menos quais seriam as etapas e os destinos diários, mas fomos ajustando os mesmos e assim sem termos os alojamentos previamente marcados estavamos mais libertos dessa obrigação de rolar para lá chegar.

Portanto o conselho que deixo é terem um macro-plano de intenções de etapas diárias e fazerem em andamento as reservas dos alojamentos quando se aproximam o suficiente para decidir a meta do dia.

Nós reservamos quase tudo via app móvel do Booking, excepto o alojamento no parque de campismo de Castro Verde que fizémos por chamada telefónica.

Hotel + Alojamento Local + Parque de Campismo

Em Chaves ficámos num pequeno e antigo hotel num quarto triplo e com pequeno-almoço, cada um pagou nem chegou a 13€... :)

Nos restantes dias fomos pernoitando em alojamento local, e pagámos entre os 50€ e os 80€, o que a dividir por três acaba por não ser nenhum exagero.

A última noite foi nos bungalows do parque de campismo de Castro Verde que são basicamente casas, não sei porque lhes chamam bungalows.

Apenas no alojamento local em Góis as bicicletas não pernoitaram connosco e ficaram numa garagem, de resto vieram sempre connosco para as casas/quartos.

Calhou pelo menos uma vez a cada um dormir na sala, sendo que eu fui o último no parque de campismo e a cama era enorme - azar, não tenho culpa de ter calhado uma boa cama na sala no último alojamento :)

Todos nós ressonávamos, pelo que dica importante: levar tampões para os ouvidos! Deu-me muito jeito...

5. Refeições

Felizmente no nosso grupinho ninguém era esquisitinho com a comida o que nos permitiu mais uma vez repartirmos as refeições principais de almoço e de jantar, diminuindo assim os custos. Como muitas vezes no interior as doses são generosas pediamos quase sempre apenas dois pratos e chegava bem para os três.

Apenas os pequenos-almoços e as refeições ligeiras que iamos consumindo ao longo do caminho eram pagas em separado pois nem todos comiamos o mesmo. Também parámos várias vezes em supermercados e afins para comprar frutas, barrinhas e líquidos.

Muitas vezes enchiamos as nossas garrafas de água em torneiras de cafés e restaurantes, infelizmente não conseguimos encher nas fontes e fontanários pois estavam quase todos secos. Recordo no entanto que bebemos sofregamente em Vila de Rei, numa das poucas fontes que encontrámos, e que jorrava uma água deliciosa ao travo.

Portugal é tem um manacial gastronómico fenomenal, os Italianos e Franceses tem a fama toda mas a nossa comida típica e regional é algo de agradar aos deuses. Deliciámo-nos opiparamente de Norte a Sul. E constatámos que os preços aumentam à medida que se desce por Portugal a baixo.

Fomos bastante constantes nas bebidas... ao almoço era sempre vinho branco, que escorrega como refresco, e à noite era tinto para dormirmos ainda melhor.

Comemos os pratos regionais e os do dia, dividindo as despesas as refeições completas oscilaram entre os 6€ (!!!) e os +-18€. E comemos como Abades! Como Reis! Como Imperadores!

(razão pela qual ao fim de tanto km e caloria queimada acabei quase com o mesmo peso com que comecei a travessia da EN2)

6. Trajeto

A EN2 é sem dúvida uma atração turística que está sub-aproveitada... diria mesmo que está muito mal aproveitada.

Está mal divulgada, apesar do push pré-eleições do atual primeiro-ministro que falou e promoveu a EN2 como foco turístico esta deveria ter muito mais foco.

Tem má sinalização, mesmo má, em Vila Real quase que entrávamos numa auto-estrada pois tem uma placa com fundo branco a apontar para a mesma entrada da auto-estrada. Há muitos troços interiores com pouca ou nenhuma sinalização, obrigando-nos várias vezes a recorrer a mapas e aos telemóveis.

Tem pouco apoio e informação, e até um suposto passaporte com os tais carimbos para validar as passagens é desmotivante (nós nem nos preocupamos com isso, as fotos e videos são prova mais que suficiente), com os locais fechados ou até não assinalados, uma série de bandeiras sobre a EN2 mas com um grafismo que mal se nota a quem passa.

Portanto o meu conselho é estudar previamente o mapa e os pontos de maior dificuldade já identificados por muitos outros peregrinos.

Uma das coisas que fizémos, e que se pudesse voltar atrás não faria, foi fazer o antigo trajeto da EN2 pela IP3 durante ali uns 4 kms... basicamente é proibido e até mais ou menos perigoso apesar de ter uma berma considerável, mas os energúmenos de carro e camiões que ali ao lado passavam faziam questão de apitar e fazer razias como que a fazer-nos pagar pela ousadia de ali circular. Neste troço depois de Santa Comba Dão tem de se fazer uns kms numa estrada alternativa que não é a EN2, é o meu conselho a quem um dia fizer o trajeto... que se lixe o traçado original, em 738 kms não são um pouco de kms que tiram o mérito!

Há muitas zonas do trajeto que são idilicas, outras nem por isso. Muitas são sossegadas e seguras, outras nem por isso. Muitas tem berma larga e bom piso, outras nem por isso.

No fim de todo trajeto o sentimento de vitória, de realização, de felicidade acaba por minimizar estes troços menos agradáveis, mas... há zonas que não é para "pessoas sensíveis". E muito menos para famílias, com crianças mais pequenas.


7. Bagagem

Esta foi a minha primeira experiência em cicloturismo e até pensava que ia demasiado leve... mas afinal até levei foram coisas a mais.

Primeiro estando nós em Portugal e não num qualquer local inóspito há sempre comércio que nos acuda quando precisamos de algo, como por exemplo protetor solar que me esqueci e depois comprei.

Levei roupa a mais que não usei, e quiça me faltou uma camisola mais quentinha.
A meio da viagem comprei mais uma tshirt, pois se durante o dia ia secando a roupa que lavava de véspera - os boxers, meias e camisola e calções almofadados, já tshirt para usar depois da viagem à noite não dava para lavar...

Levei boxers e meias que não usei pois como ia lavando e secavam facilmente com o vento ou no estendal ao sol nas paragens para almoço.

Dependendo da estação que escolherem para a viagem aconselho irem o mais leve possível.

Lista do que eu levei:
- bolsa de higiene pessoal;
- boxers e meias para X dias / 2 - ir lavando e secando;
- camisola e calção - eu levei 2 conjuntos de ciclismo leves que ia lavando alternadamente;
- calças para usar de manhã cedo quando está fresquinho, e à noite para ir jantar fora;
- camisola/casaco para usar de manhã cedo quando está fresquinha e à noite;
- capacete, dado que ia atingir velocidades e locais que não conhecia;
- chapéu, eu usei debaixo do capacete;
- óculos: escuros e outros transparentes;
- 2 conjuntos de luzes traseira e dianteira;
- impermeável: andei a carregar a semana toda e só usei quando saí do comboio em Lisboa e chovia copiosamente, safou-me nos ultimos 20 minutos da viagem!
- carregador USB com três saídas;
- cabos USB Mini e USB-C;
- dois pares de sapatilhas, umas calçadas na pedalada e outras para a noite - ms facilmente se pode levar apenas um par;
- Telemóvel;
- Relógio;
- phones: usei duas vezes na viagem mas não é algo que me agrade, ir de phones na estrada, mas dá jeito para as viagens de autocarro e comboio!

Coisas que levei mas não usei, ou podia ter abdicado:
- power bank : não usei mas convêm ter;
- chinelos : levei e só usei nos alojamentos, mas podia não ter levado;
- calções de banho : levei mas não usei;
- toalha : levei e não usei;
- coluna de som USB : não usei;
- cabos elásticos;

Não levei mas devia ter levado:
- luvas, pois de manhã estava mesmo muito frio!


...


Não é uma aventura fácil mas também não é impossível!
É uma epopeia pessoal! Só é preciso decidir ir e... ir!

Boa viagem e boas pedaladas!



Post retirado do blog da viagem na EN2: https://estradan2.blogspot.com/


          

Una app de viajes en caravana para ayudar a la España vacía, premio CETT

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Una app que impulsa los viajes en caravana bajo el lema "Descubre micropueblos, vive macroexperiencias" ha sido la ganadora en la quincena edición de los Premios Emprendedores a la innovación turística. Dichos galardones son concedidos por la facultad de Turismo CETT, adscrita en la Universidad de Barcelona.


Dicha app se llama Vanwoow y se trata de un proyecto puesto en marcha por Auxi Piñero, Manuel Guisado, Javier Guisado y Ana Margarita Galindo.

Según explica el CETT, "esta aplicación quiere hacer frente a una problemática creciente, como es la despoblación, a través del cooperativismo y aprovechando el auge de personas que viajan en caravana", apunta Narcís Coll, presidente de la Fundación CETT.

"Se trata de un proyecto sostenible, que utiliza la cooperación y la economía social solidaria para ofrecer una experiencia turística nueva y de calidad. Unos valores que compartimos plenamente y queremos seguir promoviendo en beneficio del sector y de la sociedad en su conjunto”, añade Narcís Coll.

Según explica el CETT, "la innovación, la sostenibilidad y la aplicación de las tecnologías son, precisamente, algunos de los valores que el jurado ha tenido en cuenta a la hora de otorgar los premios".

Vanwoow se presenta como una "plataforma colaborativa digital de turismo responsable que une a micropueblos con viajeros itinerantes para luchar contra la despoblación rural"

Programa de ayuda

Los otros dos premiados han sido los siguientes:

  • Elisabet Cots, por el proyecto Avinturat, "el primer market place especializado que tiene como objetivo agrupar la oferta de enoturismo de Cataluña y que basa su desarrollo en la promoción de un enoturismo responsable y sostenible".
  • Luz Alvarado y Joan Sanz, por Chartok.com, "un software de operaciones y comunicación interna pensada para los hoteles y que se basa en el concepto de ‘employee journey’, a través del cual se quiere conseguir aumentar los ingresos, optimizando los procesos internos y reforzando la cultura corporativa".
Entrega del primer premio a los impulsores del proyecto Vanwoow

Los tres proyectos premiados recibirán como premio "recursos económicos, un programa de mentoring con profesionales del sector y la gestión de contactos con posibles inversores", según informa la Fundación CETT.

Los premios cuentan con la colaboración de la Diputación de Barcelona y de la Obra Social “La Caixa”.


          

NEUROARTE AL MACRO DI ROMA: “INSIDEOUT”, FOCUS SU NICOLA DUSI GOBBETTI

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L’innovativa corrente sarà protagonista, il 4 Dicembre, di un incontro con l’artista Nicola Dusi Gobbetti organizzato dall’Università La Sapienza in collaborazione con il CUI di Arezzo Ingresso gratuito Gradita registrazione
          

VBA Excel – Affecter une macro à un bouton de commande

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Si vous voulez un bouton personnalisable, vous utiliserez un bouton de commande et non un Read more

Cet article VBA Excel – Affecter une macro à un bouton de commande est apparu en premier sur Médiaforma.


          

Pasticceria naturale e macrobiotica

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Pasticceria naturale e macrobiotica

150 ricette di dolci e leccornie da tutto il mondo

È un libro con una forte impostazione macrobiotica, per cui se siete sostenitori di questa filosofia alimentare ritroverete molti dei suoi concetti.

Diciamo subito in positivo che il libro è un bel tentativo di ribaltare in chiave salutistica il concetto di dolce in favore di una pasticceria che utilizzi il più possibile gli aromi naturalmente dolci degli alimenti limitando l'uso di dolcificanti esterni, in particolare quelli accusati apertamente di portare notevoli danni all'organismo, se consumati in eccesso, come il comune zucchero bianco da tavola.

Si aggiunge poi un bel ricorso ai prodotti integrali, come la farina, con tutti i notevoli benefici che le fibre portano con se, l'abbondante presenza della frutta sia fresca che secca non consumata mai abbastanza, un buon uso di spezie per intensificare naturalmente la componente dolce delle ricette.

Purtroppo il tutto finisce qui e iniziano le note dolenti, intanto uno stupefacente ricorso in quasi tutte le ricette al sale, un elemento raramente indispensabile in pasticceria e a nostro modo di vedere molto più nocivo e pericoloso del tanto demonizzato zucchero.

L'utilizzo molto frequente delle margarine vegetali che per quanto non idrogenate non sono certo il massimo della salubrità, molto più sensato ricorrere al puro olio interpretando in chiave più moderna la pasticceria, e per fortuna in alcune ricette questo avviene.

Ma la critica più forte è alle tante inesattezze presenti nelle ricette, in diversi casi mancano i pesi specifici di alcuni ingredienti, non vengono spiegati con la dovuta attenzione passaggi chiave che poi possono determinare il fallimento della ricetta finale, ci sono evidenti errori di proporzioni che fanno immaginare chiaramente risultati ben poco convincenti.

Un giudizio suffragato dalle prove di alcune ricette che abbiamo effettuato.
Sullo sfondo rimane poi un impostazione alimentare profondamente nord Europea, crediamo difficilmente riportabile nel contesto del gusto Italiano, in particolare nel caso dei dolci, tasto molto sensibile e sentito.

Onestamente nel complesso siamo rimasti abbastanza delusi, un peccato perché l'editore ha in catalogo ottimi libri che abbiamo anche recentemente recensito.
Se possiamo permetterci un modesto parere consiglieremmo all'editore una maggiore attenzione in fase di revisione prima della pubblicazione finale dei testi.

Acquista il libro on-line


          

Più sani senza grano

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Più sani senza grano

Nuove prospettive e conoscenze su: allergie ai prodotti derivati dal grano, celiachia e intolleranza al glutine

È un libro interessante e molto ben documentato che chi ha a che fare con il problema della celiachia, sia che sia coinvolto in prima persona, sia che ne occupi per lavoro o dovere farebbe bene a consultare.

Certo il titolo forse non è proprio il massimo, si immagina così che il grano sia una specie di sostanza tossica da evitare a prescindere da tutto e potrebbe allontanare chi in prima battuta non si interessa al problema glutine.
Invece scorrendo le tante pagine si ritrova un'attenta analisi del problema e del ruolo del glutine all'interno dell'alimentazione, una chiara esposizione delle piante che non lo contengono, utili indicazioni per ovviare al suo consumo, le soluzioni pratiche per alimentarsi senza.

Per altro non ci si sofferma solo sulla celiachia vera e propria ma si allarga il discorso a diverse presunte forme di intolleranza al glutine soffermandosi sui sintomi diversi, sulle possibili diagnosi, sulle conseguenze a lungo termine, sulle terapie applicabili.
Alcune cose lasciano un po' più perplessi e ricondurre al solo glutine la responsabilità di molte insofferenze dell'organismo crediamo sia un po' troppo riduttivo, però bisogna ammettere che i riscontri degli ultimi studi confermano diverse tracce descritte nel libro.

E tutto sommato provare un periodo di alimentazione senza glutine non è una cosa difficile e impossibile come si potrebbe pensare, le alternative sono molte e molto gustose, si tratta solo di avere un po' di costanza, verificare la reazione dell'organismo e da qui trarre le proprie conclusioni personali.
In questo tipo di patologie, infatti, è sempre bene ricordare che esiste prima di ogni altra cosa la componente soggettiva di ogni individuo e che ognuno di noi reagisce in maniera diversa e diversificata alle terapie strettamente alimentari.

Detto questo giudichiamo il libro in positivo, dalla sua c'è la chiarezza dell'esposizione del problema, l'analisi delle soluzioni, le alternative applicabili e molto altro.

Fa anche molto piacere verificare la grande bibliografia che fa di supporto alle tesi esposte, rimane solo la cattiva abitudine di piegare la storia ai propri interessi cercando di suffragare le proprie tesi affermando con assoluta certezza le vicende di un passato alimentare.
Vicende che invece andrebbero suffragate con dati più oggettivi e soprattutto meno localizzati a singoli contesti.
Ma questa è una cattiva abitudine di molti autori poco avvezzi a verificare con oggettività le fonti storiche e consultarsi con un bravo esperto di storia dell'alimentazione, un po' come si fa quando ci si consulta con un bravo medico per il problema della celiachia.

Acquista il libro on-line


          

GALPÕES 150 M2 PIRAJÁ/VALÉRIA, PÉ DIREITO 8M,, ATRÁS DO MACRO DA BR 324, EM...

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2100
GALPÕES 150 M2 PIRAJÁ/VALÉRIA, PÉ DIREITO 8M,, ATRÁS DO MACRO DA BR 324, EM CONDOMÍNIO FECHADO, SEGURANÇA 24 HORAS, GALPÕES NOVOS, EXCELENTE PARA DIVERSAS ATIVIDADES, RUA ASFALTADA, TRANSPORTE NA PORTA, DISTANDO CERCA DE 500 METROS DA BR 324,...
1 banheiros 1500 m2 1 BRL/m²
Fri, 29 Nov 2019 11:05:34 -0500
          

Intralesional Oncolytic Versus Systemic Immunotherapy for Advanced Metastatic Melanoma

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ABSTRACT

Purpose: The purpose of this article is to review the intralesional oncolytic versus systemic immunotherapy patient outcomes for advanced metastatic melanoma and attempt to inform treatment guidelines for this unique population.

Method: A PubMed literature search was conducted with search terms advanced metastatic melanoma, oncolytic intralesional therapy, and systematic immunotherapy. Fifty-six pertinent articles were retrieved and serve as the basis for this clinical review.

Results: A combination of intralesional treatment modalities and systemically-administered immunomodulatory agents have been proposed as a promising avenue for the treatment of metastatic melanoma.

Conclusion: Tumor immunotherapy is becoming an appealing strategy among different therapeutic options of unresectable and metastatic melanoma. Several clinical trials demonstrated the efficacy and tolerable toxicity of systemic immunotherapy by Ipilimumab, CTLA-4 inhibitor, and anti-programmed death receptor-1 antibodies, Nivolumab and Pembrolizumab, in patients with advanced melanoma. The combination of Ipilimumab with Nivolumab marked the beginning of a new era for melanoma immunotherapy. Whereas, nivolumab and pembrolizumab show more preferable safety profile than ipilimumab, and greater efficacy and improved prognosis in melanoma patients. The unique intralesional oncolytic therapy with Talimogene laherparepvec that genetically modified to target tumor cells, and boost the antineoplastic immune response through release of tumor-derived antigens (TDA) and granulocyte-macrophage colony-stimulating factor (GM-CSF), significantly improved the treatment-related grade IIIB/IIIC/IVA of advanced melanoma. Further clinical analysis of combinative immunotherapy is needed to determine the safety, tolerability, and efficacy for patients with regional or distant metastatic melanoma, especially accompanied by the visceral disease that cannot be adequately addressed by surgery.

Keywords: T-VEC (Talimogene laherparepvec), Ipilimumab, Pembrolizumab, Nivolumab, Intralesional Oncolytic Therapy, Systematic Immunotherapy, Advanced Metastatic Melanoma.


          

Earlier Detection of Prediabetes in Reducing the Burden of T2D in America

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Type 2 diabetes (T2D) is one of the most common and costly chronic diseases faced worldwide, and is a significant problem in the United States (U.S.).1 According to the CDC, in 2015, 30.3 million Americans had diabetes.2 Another 84.1 million had prediabetes, a condition that usually leads to T2D within five years.2 The total estimated cost of T2D in 2017 was $327 billion, including $237 billion in direct medical costs and $90 billion in reduced productivity.3 How do we win the war against T2D? We must focus on the importance of screening and prevention. Over 90% of people in the U.S. with prediabetes remain undetected. Prediabetes is associated with the simultaneous presence of insulin resistance and beta cell dysfunction, abnormalities that start before glucose changes are detectable.4 Observational evidence shows associations of prediabetes with early forms of nephropathy, chronic kidney disease, neuropathy, diabetic retinopathy, and increased risk of macrovascular disease.4 Prediabetes, or impaired glucose tolerance (IGT) and/or impaired fasting glucose (IFG), puts one at higher risk for developing T2D.5 Recognizing high-risk people is mandatory but the question arises on how to recognize normal people who are at risk for T2D in their future. The oral glucose tolerance test (OGTT) has been the mainstay for diagnosing diabetes for decades, but the U.S. has gotten away from it as a screening tool. With earlier detection of impaired fasting glucose and impaired glucose tolerance by using the OGTT for screening, the burden of T2D in the U.S. will be significantly reduced. Earlier detection in the dysfunction of glucose metabolism will identify those who are already on the path to diabetes, and will allow for earlier interventions, which will improve the morbidity and mortality of lives long term and will save billions of dollars lost in the treatment of T2D.


          

Así es la nueva Telefónica: cinco líneas de actuación que marcarán su futuro

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Así es la nueva Telefónica: cinco líneas de actuación que marcarán su futuro

Tras el Consejo de Administración celebrado en Barcelona, Telefónica, con su presidente ejecutivo José María Álvarez-Pallete al frente, ha detallado las medidas aprobadas que llevarán a cabo para construir lo que la propia compañía denomina "la nueva Telefónica".

Este nuevo plan de acción de Telefónica, que comprende cinco líneas de actuación principales, gira alrededor de tres ejes: priorizar los mercados donde Telefónica puede ser relevante y crecer con un modelo sostenible a largo plazo; impulsar las oportunidades de mayor potencial de crecimiento afianzando el valor de las infraestructuras; y aumentar la agilidad y la eficiencia. Veamos una por una esas cinco medidas.

Cuatro mercados clave

Mercados Clave

En la actualidad, España, Brasil, Alemania y Reino Unido constituyen los principales mercados para Telefónica; de hecho, aunque a cierre del tercer trimestre de 2019 el Grupo estaba presente en 14 países, estos cuatro concentraban 218,1 millones de accesos (el 63% del total) y el 80% de ingresos, Oibda y flujo de caja operativo (OpCF).

Asegura Álvarez-Pallete que, en los últimos años, han reforzado su posicionamiento en esos cuatro países, tanto orgánica como inorgánicamente, pero son mercados de gran dimensión y con un gran potencial de crecimiento, por lo que han decidido concentrar en ellos sus inversiones.

Eso sí, bajo la dependencia del consejero delegado de Telefónica, Ángel Vilá, se mantiene a los cuatro responsables de estos mercados: Emilio Gayo (España), Christian Gebara (Brasil), Mark Evans (Reino Unido) y Markus Haas (Alemania). En cuanto a las consecuencias del Brexit, Telfónica ha reiterado que Reino Unido continuará siendo un mercado clave para la compañía; de hecho, será el primer país donde desplegará su 5G comercial.

Segregación de Hispanoamérica

Hispam

Hace ya 30 años que Telefónica decició apostar por Latinoamérica y sus operaciones allí han supuesto un motor de crecimiento para la compañía. Sin embargo, Álvarez-Pallete reconoce que, en los últimos años, "las condiciones particulares en estos mercados" han mermado su contribución por distintos motivos (entorno macro y regulatorio, mayor presión competitiva, una escala insuficiente o la volatilidad de las divisas) y, como consecuencia, sus operadores en esos países "se han debilitado".

Es por ello que Telefónica ha decidido adoptar un "spin-off operativo", o lo que es lo mismo, un nuevo modelo para sus operaciones en Hispanoamérica, que pasan a gestionarse como una unidad autónoma con un equipo dedicado. Esta unidad aglutinará los negocios de Telefónica en todos los países de Latinoamérica donde hoy opera, salvo Brasil: México, Colombia, Ecuador, Venezuela, Perú, Argentina, Uruguay y Chile.

Esto conllevará la revisión del portafolio de activos en Hispanoamérica con el objetivo de modular su exposición a la región y crear las condiciones para maximizar su valor. En este sentido, Álvarez-Pallete reconoce que están abiertos a "contemplar todas las opciones", incluyendo posibles ofertas, y que "si es necesario reducir nuestra exposición, la reduciremos".

Lanzamiento de Telefónica Tech

Tech

Para impulsar el crecimiento en los servicios de mayor potencial, nace Telefónica Tech, una nueva unidad que reunirá la propuesta de valor para el segmento B2B, enfocándose en tres negocios: ciberseguridad, IoT y Big Data, y cloud, áreas en los que, de forma agregada, la compañía asegura que está creciendo en ingresos por encima del 30% anual.

Telefónica Tech integrará las unidades globales dedicadas actualmente al desarrollo y prestación de estos servicios, y contará con los equipos comerciales de cada país para su venta. Con ello, además, pretenden exportarlos mediante alianzas a otros países en los que no están presentes y generar más de 2.000 millones de euros de ingresos adicionales en el año 2022.

Creación de Telefónica Infra

Infra

Otra unidad de nueva creación, que nace con el 50,01% de Telxius como primer activo, es Telefónica Infra, que englobará las participaciones accionariales del Grupo en vehículos de infraestructuras de telecomunicaciones. El objetivo de ello es potenciar el valor de los activos de la compañía y desarrollar modelos alternativos de despliegue de infraestructuras que aceleren el crecimiento.

En palabras de Álvarez-Pallete, "Telefónica Infra ambiciona ser una de las mayores unidades de infraestructuras de telecomunicaciones del mundo, preparada para canalizar la explosión del tráfico". Esta unidad les permitirá incorporar posibles socios y tendrá un equipo gestor que se centrará en el desarrollo y monetización de torres, sistemas de antenas distribuidas, data centers -incluido EDGE-, proyectos greenfield de fibra y cables submarinos, etc.

Nuevo modelo operativo

Centro Corporativo

Con el fin de ganar agilidad y acelerar la ejecución de su estrategia, Telefónica ha decidido evolucionar su modelo operativo hacia un planteamiento más sencillo, transparente y ágil con los clientes. Esto implica adaptar el funcionamiento del centro corporativo para focalizarse en aquellas actividades que aportan un valor diferencial a todas las unidades de la nueva Telefónica (operadoras, Telefónica Tech y Telefónica Infra).

De esa forma, pretenden eliminar algunas duplicidades existentes con las estructuras de los países, reducir la complejidad, mejorar la eficiencia y maximizar las sinergias entre todas las unidades, así como impulsar los planes de simplificación y digitalización de las operaciones.

También se simplifica el organigrama de la compañía, de manera que las unidades operativas de los cuatro grandes mercados van a seguir dependiendo del consejero delegado, Ángel Vilá, incluyendo la filial de tecnología (Telefónica Tech) y la de infrastructuras (Telefónica Infra), mientras que Telefónica Hispam pasa a depender de la directora financiera, Laura Abasolo.


          

Dónde comprar el Huawei Nova 5T más barato: comparativa mejores ofertas con operadores

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Dónde comprar el Huawei Nova 5T más barato: comparativa mejores ofertas con operadores

Los operadores siguen fortaleciendo sus catálogos de móviles a plazos de cara a la campaña de navidad y tras incorporar los Samsung Galaxy A40, A50 y A70, el Sony Xperia 10 o varios modelos de Xiaomi, llega ahora otro de los smartphones aspirante a superventas en gama media/alta por su equilibrio entre especificaciones y precio, el Huawei Nova 5T.

Destacado por su cámara principal cuádruple de 48 megapíxeles (f/1.8) + 16 megapíxeles (13 mm, ultra gran angular) + 2 megapíxeles (macro) + 2 megapíxeles (profundidad), el Hauwei Nova 5T es un Android 9.0 con pantalla de 6,26 pulgadas (412 ppp), procesador HiSilicon Kirin 980 de ocho núcleos a 2.5 GHz, 6 GB de RAM, almacenamiento de 128 GB no ampliables, sensor de huella lateral, 4G de hasta 600 Mbps, NFC, batería de 3.750 mAh con carga rápida 22W y una cámara frontal de 32 megapíxeles (f/2.0).

Huawei Nova 5T con Movistar, Vodafone y Orange con auriculares de regalo

Comenzaremos con un resumen donde comparamos en igualdad de condiciones el precio definitivo disponible en cada operador en el que ya se encuentran sumados el pago a plazos, la cuota de la tarifas respectiva y el IVA para los tipos de consumo más habituales.

Yoigo será el operador donde comprar el Huawei Nova 5T a plazos más barato aunque también el único donde habrá que pagar un pago final una vez terminada la permanencia si quieres quedarte con el teléfono. Sin pago final, Vodafone y Orange comparten prácticamente el mismo precio final aunque Vodafone incluye dos mini altavoces bluetooth de regalo.

Comparativa Precios A Plazos Del Huawei Nova 5t Con Tarifas De Movistar Vodafone Orange Y Yoigo

Más allá de la comparativa de precios, si estás interesado en conocer los detalles concretos que cada operador aplica en el pago a plazos, sus posibles comisiones y todas las combinaciones de tarifas disponibles, os dejamos con un resumen específico de cada operador:

Con Movistar, podrás comprar el Huawei Nova 5T sin comisión con pago a plazos de 33,33 euros mensuales durante un año, pero si aumentas las mensualidades, se aplican la correspondiente comisión como se refleja en la siguiente tabla:

Precios Huawei Nova 5t A Plazos Con Tarifas Movistar

En Vodafone, además de incluir los dos mini altavoces de regalo, el precio más reducido se aplica únicamente a las tarifas con datos ilimitados, con o sin fibra.

Precios Huawei Nova 5t A Plazos Con Tarifas Vodafone

En Orange también vemos como el precio del Huawei Nova 5T más reducido corresponde cuando va asociado a las tarifas Love Medio, Love Intenso o tarifas Go desde 28 GB.

Precios Huawei Nova 5t A Plazos Con Tarifas Orange

Aunque como comentábamos al comienzo, Yoigo será el operador donde comprar el Huawei Nova 5T más barato, el precio más reducido se da únicamente con el combinado de fibra y móvil más completo. Con las tarifas de 30 y 40 GB, el precio final es más similar al ofrecido en Vodafone y Orange.

Precios Huawei Nova 5t A Plazos Con Tarifas Yoigo

          

Prevención de catarros y resfriados

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Prevención de catarros y resfriados
Infecciones víricas de las vías respiratorias superioresTodos los años las patologías o infecciones víricas que afectan a las vías respiratorias superiores (IVRS) (gripe, resfriado, faringitis, bronquitis) provocan entre la población…

Aunque son patologías agudas normalmente autolimitadas en el tiempo (con una duración, en general, no superior a 7 días), suponen un problema de salud pública de primera magnitud, no sólo por su incidencia en el sistema sanitario sino también porque constituyen las causas más frecuentes de bajas laborales y escolares.

Del impacto social y sanitario de los procesos víricos respiratorios nos dan una idea los datos del Ministerio de Sanidad: la proporción de población afectada durante las epidemias anuales oscila entre el 5 y el 15% en poblaciones grandes, y es superior al 50% en grupos de población cerrados, como establecimientos escolares o asilos. Según el Sistema de Vigilancia de la Gripe en España (SVGE), en la campaña de 2018-2019 se atendieron 490.000 casos de gripe en atención primaria, con 35.300 hospitalizaciones confirmadas (de las que 2.500 requirieron ingreso en UCI), y se produjeron 6.300 defunciones atribuibles a la gripe.

Su transmisión se produce por vía aérea, a través de gotas en aerosol cargadas de virus (procedentes de secreciones nasales, bronquiales o saliva): las «gotas de Flügge», y los «corpúsculos de Wells», minúsculas gotitas que son emitidas con la tos, los estornudos o simplemente al hablar, y que alcanzan una dispersión de hasta 1 metro desde el emisor. Este mecanismo permite una abundante y rápida propagación de los virus en el entorno. Se produce también una autoinoculación nasal o conjuntival a través de las manos contaminadas o pañuelos reutilizables.

El principal factor predisponente que facilita la proliferación y diseminación de los virus responsables son las bajas temperaturas del invierno, que provocan una ralentización del sistema inmunitario humano, una reducción de la movilidad de los cilios de la nariz y una disminución del calibre de los vasos sanguíneos que irrigan la mucosa nasal. Otros factores que facilitan la infección son: fatiga excesiva, estrés emocional, alteraciones rinofaríngeas alérgicas o fase intermedia del ciclo menstrual.

En los climas templados, las epidemias estacionales de estos virus de vías respiratorias se producen sobre todo durante el otoño e invierno, mientras que en las regiones tropicales pueden aparecer durante todo el año, produciendo brotes más irregulares. La gripe se difunde en una comunidad en un tiempo de 6 a 8 semanas. Por lo general son los niños quienes introducen los virus en el hogar, y el índice de afectación secundaria depende de la edad del individuo y de su estado inmunitario. Dicha propagación suele ocurrir en forma de epidemia y se produce en dos niveles: el primero en el entorno familiar, y el segundo en lugares cerrados e instituciones semicerradas.

32 EF581 PROFESION PREVENCION CATARROS tabla 1Entre las posibles complicaciones de las IVRS destaca por su morbimortalidad la neumonía, producida por infecciones bacterianas secundarias pulmonares (es más frecuente en ancianos, pacientes con cardiopatías previas, enfermedades pulmonares crónicas o inmunodeprimidos), así como las bronquitis, faringitis, sinusitis y otitis. Los niños padecen resfriados a menudo, suelen tener el primero en su primer año de vida y, a los 6 años, son especialmente propensos a padecerlos. En Europa, los niños pequeños tienen una media de 5-8 infecciones por año, desde septiembre a finales de abril, sufriendo otras complicaciones como la otitis media (tabla 1).

32 EF581 PROFESION PREVENCION CATARROS tabla 2Gripe y resfriado, ¿es importante diferenciarlos?
La gripe y el resfriado son patologías agudas de origen vírico y, en condiciones normales, autolimitadas en el tiempo (generalmente duran 1 semana). Ambas tienen en común una sintomatología similar, una alta incidencia y un abordaje terapéutico sintomático (tabla 2).

Los síntomas más típicos del resfriado común, o catarro, son la ausencia de fiebre o fiebre baja e inflamación y edema de las vías respiratorias superiores (nariz, garganta, tráquea, laringe, senos paranasales), ojos y oídos. Suelen ir acompañados de inapetencia y sensación de malestar general. Todo ello se traduce en frecuentes estornudos, congestión nasal, rinorrea acuosa y picor de garganta. Al evolucionar la sintomatología, las secreciones nasales adquieren una consistencia espesa, incluso purulenta, y aumenta la producción de tos.

Los síntomas y signos característicos de la gripe son: escalofríos, sudoración y fiebre de inicio brusco con malestar y dolores musculares generalizados (acompañados de debilidad y fatiga), y dolor de cabeza, tos seca y dolor de garganta. La fiebre y los dolores musculares suelen persistir unos días, aunque la congestión y la falta de energía pueden durar varias semanas. La convalecencia suele ser larga, durando el malestar general, la astenia y la tos hasta 2 semanas.

Un resfriado requiere unos pocos días de reposo, y puede mitigarse con algún medicamento que amortigüe los síntomas más marcados del cuadro. Por el contrario, una gripe puede tener un desarrollo y unas secuelas más importantes, que requieren un diagnóstico médico y unos cuidados más precisos para evitar complicaciones en personas predispuestas, como ancianos, niños, enfermos crónicos, etc. (figura 1).

32 EF581 PROFESION PREVENCION CATARROS figura 1

Las IVRS agudas son las consultas más frecuentes en la farmacia comunitaria en las estaciones de otoño e invierno, por lo que la valoración por parte del farmacéutico comunitario de criterios de posible gravedad o de situaciones especiales de riesgo que obliguen a la derivación al médico será fundamental para su adecuada resolución. Dicha actuación consiste inicialmente en evaluar la banalidad o no del proceso catarral, valorando los síntomas que el paciente presenta para decidir si es mejor aconsejar la derivación al médico. En caso de no existir motivos para ello, se indicarán las medidas terapéuticas (farmacológicas y no farmacológicas) más adecuadas en función de las características individuales del paciente, aliviando los síntomas y teniendo en cuenta que existen determinados pacientes en situaciones especiales para los cuales el tratamiento farmacológico puede estar desaconsejado, o en quienes su utilización debe realizarse con precauciones específicas. Además, es necesario proporcionar consejo farmacéutico para la prevención del contagio.

Prevención de las IVRS
El farmacéutico comunitario dispone hoy de un amplio arsenal terapéutico para ayudar a mejorar el estado de los pacientes y aliviar los síntomas asociados a estas enfermedades respiratorias, siempre que no se presenten complicaciones asociadas que requieran la derivación al médico.

Existen, además, una serie de medidas de carácter profiláctico que son aconsejables en los pacientes afectados. Se trata de medidas higiénico-preventivas que no sólo contribuyen a aliviar las molestias, sino que además permiten prevenir y reducir la transmisión de los virus entre personas y el autocontagio.

Medidas preventivas

  • Evitar el contacto con las personas afectadas al menos durante los 2-4 primeros días del proceso. Autoaislarse en caso de malestar, fiebre u otros síntomas gripales.
  • Lavarse frecuentemente las manos, con jabón y agua caliente o gel desinfectante.
  • Evitar los locales cerrados o mal ventilados y los lugares donde se reúnen muchas personas.
  • Evitar los cambios bruscos de temperatura y las aglomeraciones, y no salir de lugares con calefacción a zonas de frío sin abrigarse.
  • Evitar el consumo de tabaco y alcohol, ya que suponen un sobresfuerzo para el sistema inmunitario y las vías respiratorias.
  • Utilizar pañuelos desechables y eliminarlos a continuación.
  • Tapar nariz y boca al toser y estornudar, lavándose siempre después las manos.
  • Evitar frotarse los ojos después de sonarse o estornudar.
  • Seguir una dieta sana y equilibrada rica en frutas y verduras que proporcione un aporte vitamínico y mineral completo.
  • Por su carácter antioxidante, el consumo de vitamina C (en dosis de 1 g diario), pese a ser controvertido, tiene una amplia aceptación y algunas evidencias de su efectividad.
  • Mantener una buena hidratación (zumos de frutas, infusiones, agua, caldos, etc.), pero sin exagerar.
  • Evitar el estrés. Parece ser un factor importante de descenso en la actividad del sistema inmunitario, lo que nos hace más propensos a enfermar.

32 EF581 PROFESION PREVENCION CATARROS 2Medidas paliativas

  • Humidificar el ambiente adecuadamente. Es fundamental para mantener la humedad en las vías respiratorias y aumentar la fluidez de la mucosidad.
  • Reposo en cama, con la cabeza elevada, pero evitando un excesivo abrigo.
  • Aumentar la ingesta de líquidos (sobre todo caldos de verduras y zumos de frutas) ayudará a fluidificar las secreciones respiratorias.
  • Recomendar la utilización de vaselina para los labios y la nariz enrojecida.
  • Hacerse vahos de vapor para evitar la congestión nasal (humidificadores).
  • Evitar las pastillas de regaliz, ya que producen sequedad y, en algunos casos, pueden alterar la presión arterial.

Coadyuvantes no farmacológicos para los diferentes síntomas

  • Congestión nasal: el tratamiento de elección para niños, embarazadas e hipertensos es el suero fisiológico o el agua de mar.
  • Dolor de garganta: debemos recomendar hacer gárgaras, un remedio casero con una cucharada de sal en un vaso de agua tibia.
  • Estado febril, malestar general: hacer reposo en cama en una habitación fresca y no muy seca, con ropa ligera, y evitar esfuerzos, cambios bruscos de temperatura y ambientes cargados. Mantener una buena hidratación.
  • Estornudos/rinorrea: debemos recomendar el uso de pañuelos desechables, y que el paciente se lave frecuentemente las manos y evite frotarse los ojos. Se puede emplear vaselina o alguna crema hidratante para la nariz irritada y los labios.
  • Dolor de oídos: se puede aliviar aplicando calor local o instilando unas gotas de aceite de oliva.
  • Tos: emplear demulcentes, recomendar la ingesta abundante de líquidos y las gárgaras con agua tibia salada, y evitar los ambientes cargados. Existen algunas evidencias del efecto beneficioso de la miel, aunque no se debe utilizar en niños menores de 1 año.
  • En general, es recomendable humidificar el ambiente, aunque no debe añadirse al agua mentol, eucalipto, etc., pues no hay evidencia de ningún beneficio. Es preferible realizar inhalaciones o vahos de vapor simplemente con agua o suero fisiológico.

Inmunomoduladores y otros
Además de las medidas preventivas citadas, que podemos considerar clásicas o tradicionales, en los últimos tiempos han surgido nuevos conceptos que abren posibilidades, aunque no en todos los casos se dispone de evidencia científica contrastada. A ciertas sustancias presentes en vegetales y hongos se les atribuyen propiedades modificadoras de la respuesta biológica, potenciadoras y estimulantes del sistema inmunitario que podrían ser útiles en el tratamiento y prevención de ciertas enfermedades, entre las que se encuentran las IVRS.

En el caso de los hongos, sus propiedades parecen tener su origen en su contenido en germanio, que se relaciona con la actividad del interferón en el organismo, sustancia que éste genera como elemento fundamental del sistema inmunitario. Entre estos hongos, de los que se están estudiando sus posibles propiedades inmunomoduladoras, se encuentran los ascomicetos y basidiomicetos: Agaricus blazei (A. brasiliensis, A. subrufescens), Ganoderma lucidum, G. pfeifferi, Inonotus obliquus, Lentinula edodes, Coriolus (Trametes) versicolor, Hericium erinaceus, Ophiocordyceps (Cordyceps) sinensis, Pleurotus ostreatus, Rozites caperata, Sparassis crispa, Tremella mesenterica y T. fuciformis.

32 EF581 PROFESION PREVENCION CATARROS 3Ganoderma lucidum es un hongo al que la terapéutica actual dedica especial interés. Usado desde hace mucho tiempo por la medicina oriental, en la literatura científica se encuentran numerosos artículos en los que se estudian sus componentes bioquímicos y sus propiedades farmacológicas en los más diversos campos de la farmacoterapia. En el basidiocarpo, micelio y esporas de G. lucidum se encuentran más de 400 compuestos bioactivos que incluyen triterpenoides, polisacáridos (glucanos), nucleósidos, esteroides y oligoelementos con actividad antioxidante, antirradicales libres, inmunomoduladora, hipolipemiante, hipoglucemiante, antihipertensiva, analgésica, antiinflamatoria, antiviral (incluyendo anti-VIH), antibacteriana, hepatoprotectora, inductora del sueño, etc.

Estudios in vitro e in vivo sugieren que los polisacáridos de G. lucidum (PSGL) estimulan las células inmunes, incluidos los linfocitos B, linfocitos T, células dendríticas, macrófagos y linfocitos citolíticos (células NK: natural killer). Existen también algunos estudios in vivo que muestran el incremento de los mecanismos de defensa en animales y humanos.

Un reciente ensayo clínico mostró que suplementos alimenticios de salvado de arroz fermentado con Lentinula edodes lograban un incremento significativo de la producción de interferón gamma, pero no aumentaban la efectividad de las células NK. Por otro lado, en estudios sobre algunas especies como Ganoderma lucidum (reishi) o Lentinula edodes (shiitake), se demuestra que el sistema inmunitario de un organismo sano no se ve afectado por los metabolitos de estos hongos. Sólo actúan cuando las defensas están bajas, por ello se consideran tanto reguladores como potenciadores del sistema inmunitario.

Para estos macromicetos se proponen a menudo nuevas aplicaciones y se publican resultados de investigaciones que parecen aportar elementos de interés en el campo de la farmacoterapia, aunque no siempre con las garantías de fiabilidad y validez exigibles para su traslado a la práctica clínica, algo que se señala a menudo en algunas revisiones y metaanálisis. Los propios autores de los trabajos incluidos en los metaanálisis reconocen en muchos de ellos que los resultados no son concluyentes o tienen escasa significación clínica, a pesar de presentar significación estadística, y en muchos casos se trata de ensayos en los que el elemento fúngico se ha utilizado como coadyuvante de un tratamiento con un fármaco convencional.

Entre las especies vegetales cuya utilidad en la prevención y tratamiento de las IVRS se ha estudiado en los últimos años tenemos: Aster spathulifolium, Echinacea spp., Panax ginseng, Pelargonium sidoides, Pinus thunbergii, Punica granatum, Rhodiola rosea, Schisandra chinensis y Thuja orientalis.

La raíz y el rizoma de equinácea contienen polisacáridos, compuestos poliacetilénicos y fenólicos de actividad inmunoestimulante. Se trata de un mecanismo no específico: se ha observado que estimula in vitro la producción de citocinas que tienen capacidad de activar los linfocitos, incrementando la fagocitosis y la actividad de las células efectoras. También origina a partir de macrófagos y linfocitos la producción de factor de necrosis tumoral e interferones de actividad antitumoral y antiviral. Se utiliza en la profilaxis de IVRS y como coadyuvante en tratamientos quimioterápicos. Panax ginseng parece tener también una acción inmunoestimulante. Thuja orientalis, Aster spathulifolium y Pinus thunbergii incrementarían la resistencia a la infección vírica en las células del tracto respiratorio. Ensayos con extracto polifenólico de Punica granatum muestran una inhibición de la replicación del ARN viral, potenciando el efecto antiinfluenza de oseltamivir.

Parece existir evidencia, aunque limitada, de la eficacia de Pelargonium sidoides ante infecciones víricas de las vías respiratorias y sus complicaciones: rinosinusitis, faringitis, bronquitis, etc., debido a las propiedades antivirales, antibacterianas y mucolítico/expectorantes del extracto etanólico de su raíz. El mecanismo parece relacionarse con una modulación de la respuesta inmune no específica del huésped por estimulación en la liberación del factor de necrosis tumoral alfa (TNF-α), interferón β (INF-β) e interleucinas, y un incremento de la actividad de las células NK.

Iota-carragenina es un polímero de galactosa sulfato obtenido de algas rojas marinas de la familia Rhodophyceae que, administrado por vía nasal al 0,12%, forma una película protectora e hidratante sobre la mucosa que es eficaz frente a diversos virus (rinovirus humano, virus sincitial respiratorio, coronavirus, adenovirus, virus parainfluenza e influenza). Los ensayos in vitro e in vivo en humanos indican que esta barrera física interfiere en la adhesión de los virus del resfriado en las células de la mucosa nasal, disminuyendo la carga viral en más de un 90%. Ensayos clínicos recientes muestran que este mecanismo de acción puede ser de utilidad en la prevención de la infección viral y el contagio, así como en el alivio de los síntomas de gripe y resfriado.

32 EF581 PROFESION PREVENCION CATARROS 4Probióticos, prebióticos y suplementos
Existe cierta evidencia (aunque inconsistente debido a la heterogeneidad en la metodología de los ensayos) sobre el papel de los probióticos en la prevención de las IVRS. En un metaanálisis que incluye 10 ensayos clínicos, se concluye que el número de participantes que sufrieron uno o más procesos de este tipo es menor que en los grupos placebo. En los dos ensayos de mejor calidad los microorganismos administrados eran Lactobacillus casei DN-114001 y Lactobacillus rhamnosus GG.

Algunos estudios (reflejados en varios metaanálisis) constataron que la administración oral o intranasal de diversas sales de zinc (gluconato, acetato o sulfato) reduce el número de episodios de resfriados en niños, y acorta la duración y reduce la severidad de los procesos respiratorios en adultos (aunque no en niños), en dosis que oscilan entre 4,5 y 23,7 mg. En los estudios se observaron algunos efectos adversos, como sabor desagradable y náuseas, y anosmia en la aplicación intranasal.

Se ha ensayado el uso de un espray bucal con glicerol y tripsina frente a placebo en la prevención y tratamiento del resfriado común en voluntarios sanos que fueron inoculados con rinovirus (46 individuos en el grupo tratado). Los resultados mostraron una reducción de la carga viral en la orofaringe y una disminución de la duración de los síntomas en las personas que los experimentaron.

Diversos estudios ponen de manifiesto el interés en ciertos hongos medicinales para la prevención o tratamiento de enfermedades comunes y recurrentes en la población infantil. Destacan las conclusiones sobre los extractos de Hericium erinaceus (melena de león) ricos en compuestos activos como las herinacinas, con demostrada actividad neurológica; o los betaglucanos, capaces de modificar la composición de la microbiota intestinal, entre otras funciones. Las alteraciones en la composición de la microbiota intestinal están relacionadas con el desarrollo de obesidad y trastornos metabólicos asociados, así como con la aparición de múltiples patologías. Igualmente, el desequilibrio en la microbiota intestinal puede contribuir a la aparición de varias desregulaciones metabólicas, lo que provoca inflamación en el intestino, el hígado o el cerebro, así como a procesos que regulan el metabolismo energético.

Los prebióticos (betaglucanos) presentes en los hongos medicinales como Hericium erinaceus pueden estimular el crecimiento de la microbiota beneficiosa en el mantenimiento de la salud. Además, estos prebióticos de origen fúngico pueden inhibir la proliferación de patógenos –al aumentar el crecimiento de bacterias probióticas en el intestino y modular el sistema inmunitario–, lo que representa una nueva estrategia de valor en la prevención de múltiples patologías.

El pequeño tamaño de las muestras, la no identificación en muchas ocasiones de los principios activos existentes en los extractos vegetales o fúngicos (falta de estandarización) y las diferencias metodológicas, con defectos en la selección y aleatorización de los individuos incluidos, son sesgos que afectan a muchos de los ensayos citados, que intentaban demostrar estas acciones preventivas o paliativas de los síntomas asociados a las IVRS. Creemos, por tanto, que se necesitan estudios más amplios, rigurosos y profundos para alcanzar resultados convincentes en un campo que apunta a interesantes beneficios para la salud de la población.

32 EF581 PROFESION PREVENCION CATARROS tabla 3Vacunación (tabla 3)
La medida preventiva más importante en la actualidad sigue siendo la vacunación antigripal, especialmente entre la población con patologías que suponen un riesgo de sufrir complicaciones, aunque sólo es efectiva contra el virus influenza y no frente a los virus causantes del resfriado, ya que el amplio número de especies víricas implicadas impide en este caso confeccionar una vacuna eficaz.

Cada año la Agencia Española de Medicamentos y Productos Sanitarios recoge las normas que deben seguirse con respecto al cambio de cepas en las vacunas de la gripe para la campaña anual, siguiendo la última recomendación de la Organización Mundial de la Salud (OMS) para la situación europea del año correspondiente. Para la campaña 2019-2020, la composición corresponde a las cepas de gripe que se supone afectarán a la población española en esta temporada: A/Brisbane/02/2018 (H1N1) pdm09, A/Kansas/14/2017 (H3N2) y B/Colorado/06/2017 (linaje B/Victoria/2/87).

Durante años, las vacunas contra la gripe se han formulado con una composición trivalente: dos virus de la gripe A (H1N1 y H3N2) y un virus de la gripe B, a elegir entre los dos linajes diferentes que existen de virus B, aunque ambos están en circulación durante la mayor parte de las temporadas. Las vacunas tetravalentes para esta temporada deberán incluir el virus B/Phuket/3073/2013 (linaje B/Yamagata/16/18). Al agregar otro virus B a la vacuna, se espera conseguir un mayor grado de protección contra los influenza-virus circulantes.

La vacunación es gratuita en los centros de salud, siempre que sea dentro del periodo de campaña de cada año, pero también se puede adquirir en las farmacias con receta médica. Deben vacunarse los mayores de 65 años, las personas con alto riesgo de sufrir complicaciones en caso de padecer gripe, y las personas en contacto con estos grupos de alto riesgo, ya que pueden transmitírsela: enfermedad crónica cardiovascular o pulmonar, diabéticos, enfermedad renal o hepática crónica, inmunodeprimidos, embarazadas, trabajadores de centros sanitarios o geriátricos, policías, bomberos, protección civil, etc.

Una vez administrada la vacuna, la protección eficaz comienza después de 7 o 10 días y dura hasta 6 meses, lo que hace necesario repetir anualmente la vacunación. Aunque la efectividad de la vacunación parece ser muy variable (25-80%), en función de la edad, el grado de inmunocompetencia y la coincidencia de los componentes de la vacuna con los virus de la temporada, todas las organizaciones e instituciones nacionales y supranacionales recomiendan su empleo.

El farmacéutico comunitario (además de vacunarse por pertenecer a un grupo de riesgo, al tratarse de un profesional sanitario en contacto con pacientes de riesgo a los que puede transmitirla) debe participar en campañas de difusión y promoción de la vacunación antigripal entre los usuarios de su farmacia.

Lamentablemente, en España la cobertura de vacunación es reducida: no llega al 50% en los grupos de riesgo. En la campaña pasada, de 2018-2019, se alcanzó el 56% en mayores de 65 años y sólo el 39,8% en médicos y enfermeros. Un porcentaje insuficiente, ya que la OMS recomienda que al menos el 75% de los incluidos en grupos de riesgo se vacunen frente a la cepa del virus de cada año.

Algunas Sociedades Científicas y Colegios de Farmacéuticos han ofrecido a las Autoridades Sanitarias estatales y a las comunidades autónomas la colaboración en las campañas anuales con la administración de las vacunas por parte de los farmacéuticos comunitarios en las farmacias españolas, como se hace con notable éxito en otros países, pero no se obtuvo una respuesta favorable.

La utilidad de la administración de la vacuna de la gripe estacional en las farmacias comunitarias (por parte de farmacéuticos acreditados y formados específicamente) viene avalada por los excelentes resultados obtenidos en muchos países de nuestro entorno: Canadá, Australia, Reino Unido, Irlanda, Dinamarca, Suiza, Francia, Portugal, etc., donde han conseguido elevar de manera notable la tasa de cobertura de vacunación.

Por otro lado, un reciente trabajo de nuestro grupo de investigación ha demostrado que la opinión de que la farmacia comunitaria debe ser un punto de administración de la vacuna antigripal es ampliamente mayoritaria entre los usuarios de la farmacia (85% de los encuestados) y también entre los propios farmacéuticos comunitarios, que en un 68% están dispuestos a recibir la formación adecuada y a realizar la administración de las vacunas antigripales en sus farmacias.

Bibliografía
Abrams GD, Bishop JE. Effect of the normal microbial flora on gastrointestinal motility. Proc Soc Exp Biol Med. 1967; 126: 301-304.
Allan GM, Arroll NB. Prevention and treatment of the common cold: making sense of the evidence. CMAJ. 2014; 186(3): 190-199.
Andrés-Rodríguez, NF. Os fungos na terapéutica. Mykes. 2016; 19: 105-136.
Andrés-Rodríguez NF, Botana-Rey A, Crespo-Suárez M, Iglesias L, Pouso-Alcalde C, Rey F, et al. Gripe y resfriado. En: Andrés-Rodríguez NF, et al. [Coordinadores]. Guía para el Servicio de Indicación Farmacéutica. Vigo: Cofano, 2016; 175-188.
Andrés-Rodríguez NF, Mera-Gallego R, Piñeiro-Abad A, Acuña-Ferradanes A, Mera-Gallego I, García-Rodríguez P, et al. Vacunación antigripal en la farmacia comunitaria: opinión de pacientes y farmacéuticos. Farmacéuticos Comunitarios. 2018; 10(3): 15-24.
Bisen PS, Baghel RK, Sanodiya BS, Thakur GS, Prasad GB. Lentinus edodes: a macrofungus with pharmacological activities. Curr Med Chem. 2010; 17(22): 2.419-2.430.
Choi JY, Paik DJ, Kwon DY, Park Y. Dietary supplementation with
rice bran fermented with Lentinus edodes increases interferon-γ activity without causing adverse effects: a randomized, double-blind, placebo-controlled, parallel-group study. Nutr J. 2014;
13: 35.
Chu TTW, Benzie IFF, Lam CWK, Fok BSP, Lee KKC, Tomlinson B. Study of potential cardioprotective effects of Ganoderma lucidum (Lingzhi): results of a controlled human intervention trial. British
J Nutr. 2012; 107: 1.017-1.027.
Clarsund M, Fornbacke M, Uller L, Johnston SL, Emanuelsson CA. a randomized, double-blind, placebo-controlled pilot clinical study on ColdZyme® mouth spray against rhinovirus-induced common cold. Open J Resp Diseases. 2017; 7: 125-135. Disponible en: https://doi.org/10.4236/ojrd.2017.74013
De Diego Calonge F. Hongos medicinales. Madrid: Mundiprensa, 2011.
Eccles R, Winther B, Johnston SL, Robinson P, Trampisch M, Koelsch S. Efficacy and safety of iota-carrageenan nasal spray versus placebo in early treatment of the common cold in adults: the ICICC trial. Respir Res (Lond). 2015; 16: 121.
Food and Drug Administration. El resfriado y la gripe: prevención, síntomas y tratamientos. Disponible en: https://www.fda.gov/consumers/articulos-en-espanol/el-resfriado-y-la-gripe-prevencion-sintomas-y-tratamientos (último acceso: 29/9/2019).
Hao Q, Lu Z, Dong BR, Huang CQ, Wu T. Probiotics for preventing acute upper respiratory tract infections. Cochrane Database Syst Rev. 2015; (9): CD006895.
Íñiguez Vázquez I, Rubial Bran D, Matesanz Fernández M, Rigueiro Veloso MT, Casariego Vales E. Gripe. Guías de Práctica Clínica Fisterra, 2013. Disponible en: http://www.fisterra.com/guias-clinicas/gripe/ (último acceso: 27/9/2019).
Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, et al. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015; 2: CD007259.
Lindequist U, Kim HW, Tiralongo E, Van Griensven L. Medicinal Mushrooms [Editorial]. J Evid Based Complementary Altern Med. 2014. Article ID 806180. DOI: 10.1155/2014/806180.
Lizogub VG, Riley DS, Hegefr M. Efficacy of a Pelargonium sidoides preparation in patients with the common cold: A randomized, double blind, placebo-controlled clinical trial.
Explore J Sci Heal. 2007; 3(6): 573-584.
Ludwig M, Enzenhofer E, Schneider S, Rauch M, Bodenteich A, Neumann K, et al. Efficacy of a carrageenan nasal spray in patients with common cold: a randomized controlled trial. Respir Res (Lond). 2013; 14: 124.
Ministerio de Sanidad, Consumo y Bienestar Social. La gripe. Disponible en: https://www.mscbs.gob.es/ciudadanos/enfLesiones/enfTransmisibles/gripe/home.htm (último acceso: 28/9/2019).
Mousa HA. Herbal therapies for prevention and treatment of influenza and influenza-like illness. J Infect Dis Therapeutics 2015; 215.
Organización Mundial de la Salud. Gripe (estacional). Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/influenza-(seasonal) (último acceso: 27/9/2019).
Organización Mundial de la Salud. Questions and Answers. Vaccine effectiveness estimates for seasonal influenza vaccines. February 2015. Disponible en: http://www.who.int/influenza/vaccines/virus/recommendations/201502_qanda_vaccineeffectiveness.pdf (último acceso: 28/9/2019).
Pérez Roncero L. Atención farmacéutica en síndromes menores. Gripe y resfriado. El Farmacéutico. 2015; 526: 36-42.
Pleschka S, Stein M, Schoop R, Hudson JB. Actividad de un extracto de equinácea purpúrea frente a los virus de la influenza H1N1, H5N1 y H7N7. Revista de Fitoterapia. 2009; 9(2): 115-124.
Ríos-Cañavate JL. Ganoderma lucidum, un hongo con propiedades inmunoestimulantes. Revista de Fitoterapia. 2008; 8(2):
135-146.
Sapena Grau J, Picó Sirvent L, Morera Inglés M, Rivero Urgell M. Betaglucanos de Pleurotus ostreatus en la prevención de infecciones respiratorias recurrentes. Acta Pediátrica Española. 2015; 73(8): 186-193.
Servizo Galego de Saúde (SERGAS). Campaña de vacunación antigripal 2019. Instrucción. Disponible en: https://www.sergas.es/Saude-publica/Instrucion-campa%C3%B1a-vacinacion-antigripal (último acceso: 2/10/2019).
Sistema para la Vigilancia de la Gripe en España (SVGE). Impacto de la epidemia de gripe en España 2018-2019. Disponible en: http://vgripe.isciii.es/inicio.do (último acceso: 1/10/2019).
Suárez-Arroyo IJ, Rosario-Acevedo R, Aguilar-Pérez A. Anti-tumor effects of Ganoderma lucidum (Reishi) in inflammatory breast cancer in in vivo and in vitro models. Plos One. 2013; 8(2): e57431.
Xu Z, Chen X, Zhong Z, Chen L, Wang Y. Ganoderma lucidum polysaccharides: immunomodulation and potential anti-tumor activities. Am J Chin Med. 2011; 39(1): 15-27.


          

2019 : Best dressed male politicians in the world

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You have probably already heard about the importance of dressing well. How we dress affects the way we THINK, FEEL, ACT and the way others react to us. This is especially true for politicians who undergo public scrutiny and are often representative of their nations. 1.Emmanuel  Macron is a French politician serving as President of France... Continue Reading →
          

2019-11-19 - 191119

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Josh Sudweeks posted a photo:

2019-11-19 - 191119

Random macro before bed.


          

Brief aus Paris an Putin: Macron weicht wieder von antirussischem NATO-Konsens ab

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Preview Ein Brief von Macron an Putin, in dem er vorschlägt, die russischen Angebote eines Moratoriums von Mittelstreckenraketensystemen ernsthaft zu überprüfen, ist an die Öffentlichkeit gekommen. Das weicht von der bisherigen NATO-Rhetorik grundsätzlich ab.
          

Hundreds Enjoy Thanksgiving Feast Courtesy of Generous Community

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More than 350 Sussex County families will be able to enjoy a Thanksgiving turkey with all the trimmings this year, thanks to the generosity of local businesses, churches and individuals who donated voluminous amounts of food for Project Self-Sufficiency participants this November.  Agency staff and volunteers recently bagged hundreds of frozen turkeys, along with fresh produce, cans of cranberry sauce, vegetables, stuffing mix, dinner rolls, and freshly baked pies and distributed them to local families. 
 
Al & Alessandra Kash, Kate & Michael McNamara, and John Mathews


This year, 2,000 pounds of fresh vegetables were provided by longtime Project Self-Sufficiency volunteer Michael McNamara and his family in recognition of McNamara’s recent birthday.  “My whole family is involved,” noted McNamara, who has supported the organization for more than 30 years.  “Not only is it my birthday, not only is it my wedding anniversary, but Thanksgiving is my favorite holiday.   All you have to do is be grateful and share what you have.  I have been fortunate in my life, so I am sharing this with my whole family.   We’re all in it together.”
 
Colleen Duffy, First Presbyterian Church of Newton

The First Presbyterian Church of Newton Youth Group, along with help from the congregation, donated 200 freshly baked apple and pumpkin pies.  The supplies for the pie baking were donated by the congregation and the apples were donated by Race’s Farm in Blairstown.  “This is our twelfth year baking pies for Project Self-Sufficiency,” noted Colleen Duffy, Associate for Family Nurture at the First Presbyterian Church.  “It has become a beloved tradition and teaches the kids the importance of sharing God’s love with those in need in our community.”
 
Al & Alessandra Kash, John Mathews

Fresh fruit was supplied by John Mathews, Hinkley Auto Sales, and retired Project Self-Sufficiency staff member and current volunteer, Stephanie Sumpman.  Frozen turkeys were donated by the ad hoc group of approximately 20 men and women known loosely as the College of Knowledge; the donation was spearheaded by Project Self-Sufficiency Leadership Council member Roy Knutsen.  The group meets at Kathy’s restaurant in Fredon and has supported everything from baseball teams to the local fire department. 
 
Volunteers from Mars and Selective Insurance

“The generosity of our friends and neighbors towards Project Self-Sufficiency participants is deeply appreciated during the holiday season,” commented Deborah Berry-Toon, Executive Director of Project Self-Sufficiency.  “We have a lot to be thankful for this year.”

Project Self-Sufficiency has provided services to families in the New Jersey counties of Sussex, Warren and Hunterdon for more than 30 years.  Programs include career guidance, computer training, help with obtaining a high school diploma, parenting skills classes, legal assistance and education, financial workshops, health education, childcare and family activities.  The agency offers help around the holidays, formal dresses during prom season, and assistance with emergency basic needs, such as food and clothing to its participants.  Most services are free, and many are open to the public. 

To donate, or to find out more about the programs and services available at Project Self-Sufficiency, call 973-940-3500 or 844-807-3500, or visit www.projectselfsufficiency.org.

          

40000 gegen Macron

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Hansgeorg Hermann. Brennende Barrikaden, demolierte Fahrzeuge, Wolken aus Tränengas und schwere Hiebe mit dem Polizeiknüppel – das 53. Protestwochenende der «Gilets jaunes» in Frankreich war erneut von Gewalt geprägt, mit zahlreichen Opfern auf Seite der Demonstrant*innen.
          

Frankreichs Gewerkschaften mobilisieren

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In Frankreich will Präsident Macron eine Rentenreform im grossen Stil durchführen mi dem Ziel, die Renten zu kürzen und das Rentenalter zu erhöhen. Am 5. Dezember kommt es zur ersten landesweiten Mobilisierung gegen das neoliberale Vorhaben der Macron-Regierung. Weitere werden wohl folgen.
          

Guédiguian fustige Macron, l’architecte d’une «restauration du capitalisme»

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Le réalisateur de Gloria Mundi qui sort en salles mercredi a déploré le discours du président de la République devant les étudiants amiénois jeudi.
          

Több francia katona meghalt Maliban

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Emmanuel Macron francia államfő közölte, hogy a legnagyobb tisztelettel adózik az áldozatok emlékének, akik a terrorizmus ellen harcoltak a Száhel-övezetben.
          

Militaires tués au Mali : comment se déroulera l’hommage national aux Invalides

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Ce lundi 2 décembre 2019, entre 15h et 17h, Emmanuel Macron présidera l’hommage national aux 13 militaires morts au Mali le 25 novembre, en présence de nombreux Palois. Un hommage national à ne pas confondre avec un deuil national La cérémonie d’hommage, présidée par Emmanuel Macron ce lundi 2 décembre 2019, honorera la...
          

3 Key Metrics Suggest Bitcoin Price Has Completed Its Macro Bear Cycle

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Several key metrics like the RSI, MACD, and CME Futures gap point toward a bullish rally for Bitcoin price over the coming week
          

Brigitte Macron : ce surnom très flatteur que lui vaut son travail à l'Élysée !

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Depuis mai 2017, et la prise de fonction d'Emmanuel Macron à l'Elysée, sa femme, Brigitte, reste invariablement populaire. Surnommée la "Jane Fonda Française " par la presse étrangère, la...

Lire la suite de la news sur Public.fr


          

A Concise Guide to Macroeconomics - What Managers, Executives, and Students

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Sigma 70-300 mm f/4-5.6 Nikon F mount - 89

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Predám teleobjektív Sigma 70-300 mm f/4-5.6 DG Macro vo veľmi zachovalom stave, bez poškodenia. typ objektívu : teleobjektív min. ohnisková vzdialenosť : 70 mm max. ohnisková vzdialenosť : 300 mm svetelnosť pri min. ohniskovej vzdialenosti : f/4 ...
          

The impending end of a mania

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via Crescat capital Macro Imbalances There is a laundry list of dangerous assets bubbles in the global financial markets today that have built up over a record long US economic expansion: Highest ever global debt to GDP levels; A passive investing and ETF craze that has led to historic lofty US equity valuations across a … Continue reading "The impending end of a mania"
          

Au sein de La République en Marche, une lente mais inquiétante érosion des troupes

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En moins de 24 heures, deux députées ont quitté le mouvement fondé en 2017 par Emmanuel Macron.
          

Bras de fer entre Marcheurs et Républicains autour de la liste Béchu

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Les Républicains lancent une offensive pour récupérer des maires qui appelaient à soutenir Emmanuel Macron avant l'été.
          

Exhumation d'une conversation privée avec Macron : François Ruffin réfute toute duplicité

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François Ruffin et Emmanuel Macron avaient convenu en septembre 2016 de la "stratégie" de communication à adopter l'un contre l'autre dans le dossier Ecopla.
          

En 2018, les voyages en avion d'Emmanuel Macron ont coûté 7,9 millions d'euros

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Le président de la République a voyagé en avion pendant près de 800 heures, soit environ 67 heures de vol par mois.
          

Grève du 5 décembre : une majorité de Français soutiennent le mouvement

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Selon un sondage publié ce mardi, 64% des Français jugent qu'Emmanuel Macron "comprend mal" les "difficultés sociales".
          

Ursula Von der Leyen, une proche de Merkel adoubée par Macron

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Proche d'Angela Merkel, Ursula von der Leyen prend dimanche la présidence de la Commission, forte d'une image d'Européenne convaincue mais déjà éprouvée par une procédure de confirmation difficile, elle va devoir convaincre.

Elle a été le joker du couple franco-allemand quand toutes les autres options ont échoué dans les jours qui ont suivi les élections européennes de mai.

Son accueil au sein des institutions européennes a été plus que frileux. Le Parlement européen ne lui a donné sa confiance qu'à une courte majorité de neuf voix.

Puis trois de ses commissaires candidats ont été retoqués par les eurodéputés, un record, bousculant la procédure de confirmation et l'empêchant de prendre ses fonctions début novembre, comme prévu.

Ursula von der Leyen a finalement retrouvé le sourire mercredi, obtenant une large majorité pour son nouveau collège de commissaires, avant de prendre enfin les rênes de la Commission dimanche.

Soutenue par le président français Emmanuel Macron, cette francophile est appréciée par Paris, notamment en raison d'une bonne coopération sur les questions de défense franco-allemande.

A la tête de l'armée allemande pendant près de six ans, cette femme énergique de 61 ans fut un temps considérée comme la dauphine toute désignée de la chancelière Angela Merkel, qui l'a nommée ministre dans chacun de ses quatre gouvernements (2005-2019).

Une série de scandales ont cependant éclaboussé la Bundeswehr et son ministère pendant son mandat. Si bien que dans un sondage du quotidien Bild au printemps, les Allemands avaient fini par la considérer comme l'une des deux ministres les moins compétents du gouvernement.

- Carrière spectaculaire -

Malgré cette image écornée, Ursula von der Leyen est arrivée à Bruxelles, la ville qui l'a vue naître et grandir jusqu'au début de l'adolescence, avec un atout important: la confiance de Paris et Berlin, à l'heure où M. Macron et Mme Merkel semblaient ne pouvoir s'entendre sur rien.

Outre l'allemand, la responsable politique parle couramment le français et l'anglais. Elle a perfectionné cette dernière langue en Californie, où son mari a enseigné pendant plusieurs années dans la prestigieuse université de Stanford.

La carrière politique de "Röschen" (petite rose), son surnom en famille, est spectaculaire, même pour la fille d'un baron de la politique régionale allemande, Ernst Albrecht.

Ce n'est en effet qu'en 2002, après les Etats-Unis, qu'elle se lance pour un mandat local dans la région de Hanovre. Trois ans plus tard elle était ministre du Travail.

Femme énergique et tenace --certains la diront cassante--, ce caractère a eu du mal à passer dans le monde très masculin de l'armée.

Elle s'est aussi mise à dos une partie de la hiérarchie militaire pour avoir dénoncé des "faiblesses" et un "esprit de corps mal placé", après l'arrestation en 2017 d'un officier soupçonné de préparer un attentat contre des étrangers.

La ministre a aussi été soupçonnée un temps en 2015 de plagiat de son doctorat, un sujet très sensible en Allemagne qui a causé la chute de plusieurs responsables politiques.



- Médecin mère, ministre -

Elle a été la première femme à occuper le poste prestigieux de ministre de la Défense. A ce poste, elle a aussi multiplié les visites aux forces allemandes en Afghanistan ou en Irak.

Médecin de formation, elle est mère de sept enfants. Dans un pays où il reste difficile pour une femme de concilier carrière professionnelle et famille, elle fit régulièrement la Une des magazines avec sa progéniture, au point d'être accusée de l'instrumentaliser.

Au sein du parti chrétien-démocrate (CDU), elle s'est opposée à son propre camp sur certains dossiers, réclamant par exemple des quotas de femmes au sein de la direction des grandes entreprises.

Dans un pays frappé de vieillissement avec une natalité en fort déclin, Ursula von der Leyen reste aussi la "mère" du salaire parental dont peuvent bénéficier les Allemands pendant les 14 mois suivant une naissance.


          

گلکسی A51 سامسونگ با دوربین ماکرو 5 مگاپیکسلی

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شرکت سامسونگ در پی آن است که بزودی یک میان رده جدید به نام Galaxy A51 را معرفی کند. اسمارتفونی که از طراحی نسل جدید برخوردار بوده

نوشته گلکسی A51 سامسونگ با دوربین ماکرو 5 مگاپیکسلی اولین بار در موبایلستان. پدیدار شد.


          

FEELING CHRITMASSY WITH SOME FROSTY MACRO PHOTOGRAPHY

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Today is all regarding the crunch of icy leaves and frosted grass under my feet. My strategies for landscape digital photography had all gone out the home window today when I saw this frosted banquet for the eyes in front of me. I had weakened, I had no choice however to choose up that macro […]
          

EUR/USD. Preview of the week. Lagarde in the European Parliament, the "vendetta" of China and Nonfarm

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Bears of the euro-dollar pair again tested the ninth figure on Friday in spite of fairly strong data on the growth of European inflation. The last trading day of the week and month was indicated by abnormal price movements: the strong downward impulse faded before it started. In the last hours of the trading week, many market participants took profits without risking leaving open positions for the weekend. Therefore, EUR/USD traders closed November within the 10th figure. The pair began trading on the first day of December at the same positions. The fundamental background for the dollar is still controversial - the dollar is keenly reacting to news from the front of US-Chinese negotiations, and the euro is torn between good macroeconomic reports and the dovish intentions of ECB members.

Not many important macroeconomic statistics are expected for the EUR/USD pair during this trading week (with the exception of the ISM and Nonfarm manufacturing index). The main focus of the market will be focused on the dynamics of the development of US-Chinese trade relations and on the comments of Federal Reserve and ECB officials. Geopolitics will also play a role in determining the growth or decline of anti-risk sentiment in the foreign exchange market.

analytics5de4bd285e3b3.jpg

First of all, we are talking about the situation in Hong Kong, where the confrontation between anti-Chinese protesters and the city administration continues. Yesterday, police dispersed several thousand anti-government protesters, ending a brief lull after local elections. Last week, Trump signed bills in support of protesters, and this fact provoked a negative reaction from Beijing. Chinese officials promised Washington to retaliate, but so far these threats have not been translated into reality. Traders had the hope that the political conflict would not affect the negotiation process between the United States and China - all the same, the effects of the trade war are felt both by the United States and China. This intrigue may be resolved this week, especially in light of the approaching December 15, when next duties should come into force over Chinese imports.

If we talk about the planned speeches of the "top officials" of the central bank, which are important for EUR/USD traders, then we should highlight today's speech by the head of the European Central Bank Christine Lagarde. At 12:00 (London time), she will announce a report to members of the Committee of the European Parliament on economic and monetary issues. Since the topic of the report is directly related to monetary policy, the market will show particular interest in it. Let me remind you that in her recent speeches, she called on EU countries to bet on investments, thereby stimulating economic growth in the eurozone. Given the existing split in the ECB camp (in September, some regulator members opposed the resumption of QE), this Lagarde rhetoric was indicative: judging by everything, it will continue to exert verbal pressure on the EU countries - primarily Germany and the Netherlands - urging them to use surplus of their budgets.

She can also comment on data published on Friday on the growth of European inflation. Contrary to negative forecasts, the consumer price index rose in November, reaching 1.0% from the previous value of 0.8% (growth forecast was at 0.7%). Core inflation also showed a positive trend, rising from 1.1% to 1.3%. This is the best result in the last six months. In this context, Lagarde's personal position regarding this inflationary dynamics, as well as her comments on the moods among the members of the European Central Bank, are also of interest. The euro will receive some support if the essence of the rhetoric is reduced to a wait-and-see attitude.

ECB board member Benoit Coeure is set to speak (December 3) this week, who unexpectedly joined the dissidents at the September meeting, speaking out against the resumption of the stimulus program. Fed official Randall Quarles, who takes the post of vice chairman of oversight in the Federal Reserve, will speak on December 4.

As for macroeconomic reports, it is worth noting the ISM manufacturing index will also be published today during the US session. Previous releases of this indicator put pressure on the dollar: the index has been below the 50th mark since August, marking the worsening situation in this area. According to preliminary forecasts, a slight recovery of the indicator is expected today (from 48.3 to 49.2 points). This will put quite strong pressure on the US currency if the index declines, especially in light of the uncertain prospects for the US-Chinese dialogue.

Over the course of two days (December 2 and 4), we will also find out the importance of European PMI indices in the manufacturing and services sectors. But we are talking about final estimates, which, as a rule, coincide with the initial data. Therefore, these releases are unlikely to affect the dynamics of the EUR/USD pair.

The most important day of this week is Friday, when Nonfarm will be published. The greenback will receive significant support if the real data corresponds to preliminary forecasts. Thus, the unemployment rate should remain at the previous level - 3.6% - against the background of a fairly strong increase in the number of employees (+190 thousand). But a separate line is worth noting here, the growth rate of the average hourly wage. Analysts expect the indicator to recover - in annual terms, it should grow to a three percent mark, and in monthly terms - to 0.3% (after falling to zero). If salary data is in the green zone, it will be difficult for the EUR/USD bulls to keep their positions occupied by that moment.

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In general, the euro-dollar pair continues to trade within the range of 1.0970-1.1090: last week the bears could not push the lower boundary of this band, while the bulls could not even squeeze to the middle of the 10th figure. This week, the struggle between sellers and buyers will erupt with renewed vigor, even despite the relatively empty economic calendar.

The material has been provided by InstaForex Company - www.instaforex.com

          

Feedback review on diet

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Not sure of the macros but I've been sucking this down recentl and wanna get some feedback from you bro's and sisters 5 egg whites + one whole egg scrambled with a handful of mushrooms 1/2 a cup...
          

Five Books to Supplement Teaching Undergraduate Economics, by Nathanael Snow

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I’ve been teaching economics to undergraduates for almost a decade, and I always find primary textbooks to be too insufficient and dry to consider a course complete. So, as many professors will do, I assign supplemental books to help students make a different connection between the ideas we use in the classroom and their everyday lives or intellectual pursuits.

These books represent my personal favorites over the whole undergraduate curriculum that I have taught, rather than the best for any specific course.

 

  1. Arnold Kling, The Three Languages of Politics. (Editor’s Note: There’s an EconTalk for that!)

Used in Introduction to Economics for non-majors.

Economics often, and particularly in macroeconomics, intersects with politics. The appropriate role of a political economist is to demonstrate to the public in deliberation the relevant opportunity costs of alternative sets of rules. But it won’t matter what the political economist says if the public in deliberation are talking past one another. Kling provides a framework for understanding why public discussion falls apart, and he offers solutions. I use a class exercise in which each student presents a political issue from a perspective different from her own, seeking to use the language of the assigned political group so effectively that someone from that group would not identify the speaker as an impostor. This “Ideological Turing Test” as proposed by Bryan Caplan is expanded upon by Kling. Students learn the difference between positive and normative arguments, and how to converse in diverse groups like the classroom.

 

  1. Thomas Sowell, Basic Economics.

Used in Intermediate Microeconomics.

Armen A. Alchian and William R. Allen, in the primary text for my Intermediate Microeconomics class, Universal Economics, quote Alain A. Enthoven saying “The economic theory [most policy makers use] is the theory most of us learned as sophomores.” Students need to internalize economic intuition, the economic way of thinking, more than models and mathematical formulas. Sowell’s book is appropriate for anyone with a good high school education who wants to understand the world around them through an economic lens. Sowell provides colorful examples for every principle, though I would have been happier if he had included footnotes.

 

  1. Richard Whately, Easy Lessons on Money Matters: For the Use of Young People.

Used in Principles of Microeconomics.

The particular scholar will recall Richard Whately for having coined the term “catallactics” to describe the study of exchanges. Economists such as Francis Edgeworth, Ludwig von Mises, F.A. Hayek, and James Buchanan have claimed “catallactics” as a proper constraint on the field of study for the political economist. In Easy Lessons Whately popularizes the fundamental principles of economics for children in grade school. Though written almost 200 years ago the lessons on money, exchange, commerce, coin, value, wages, rich and poor (income distribution), capital, taxes, letting and hiring (factors of production), and interference with men’s dealings with one another (constitutions and regulations) demonstrate Whately’s proto-marginalist mastery of the economic perspective. I first assigned this to students in my History of Economic Thought course who then heartily recommended it for Principles of Microeconomics classes.

 

  1. Russ Roberts, The Choice: A Fable of Free Trade and Protectionism. (Editor’s note: There’s an #EconlibReads for that!)

Used in Principles of Macroeconomics.

Roberts’ narrative of television manufacturing in the United States has started to feel a bit dated. However, it remains in my opinion the best way for students to learn the ramifications of protectionism for prosperity and choice. I also use Roberts’ The Price of Everything to help students learn the importance of spontaneous orders, but The Choice is my choice between the two, especially as protectionism again has entered the public debate.

 

  1. Arnold Kling, Specialization and Trade. (Editor’s note: There’s an EconTalk for that, too!)

Used in Macroeconomics.

Kling appears twice on my list because he explains complex interactions with the clarity and iterative persistence necessary to penetrate reluctant minds with alien conceptions—to paraphrase Herbert Spencer. This is perhaps the happy byproduct of Kling’s many years’ teaching economics to high school students. Most of this book is a pedestrian walk through the fundamental principles of economics, explained as a fundamental framework for understanding the world rather than as a social science capable of falsifiability, as in physics. Lurking beneath Kling’s argument is a focus on the consequences of creative destruction in advanced economies. Kling’s lesson reaches its zenith in chapter 9, a long read, but the most innovative in the book. Structural dis-coordination that results from dynamic change may require different responses than the more familiar frictional unemployment experienced in earlier stages of development. The Fed does not have as much power as its supporters and critics would attribute to it. Kling’s book provides an important contrast to the mainstream presentation of macroeconomic principles, and is especially appropriate for the skeptical and curious student.

 

 

Nathanael Snow is an Assistant Teaching Professor of Economics at Ball State University. 


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De Marck Zuckerberg a Amancio Ortega: dónde viven y cuánto cuestan las casas de cinco de los hombres más ricos del mundo

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De Marck Zuckerberg a Amancio Ortega: dónde viven y cuánto cuestan las casas de cinco de los hombres más ricos del mundo

La lista Forbes 400 nos ha vuelto a mostrar recientemente quiénes son algunos de los hombres más ricos del mundo. Una lista en la que, para entrar, es necesario tener una fortuna mayor que 2.100 millones de dólares y en la que en 2019 se han mantenido a la cabeza el fundador y CEO de Amazon, Jeff Bezos, y Bill Gates en segunda posición. Los dos, además, tienen otra cosa en común y es que son vecinos. Algo que nos ha llevado a preguntarnos: ¿dónde y cómo viven los que más tienen?

Bill Gates

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La pequeña localidad residencial de Medina en Washington (Seattle) es uno de los códigos postales más ricos de todo el país norteamericano. Allí viven unas 3.000 personas con una renta per cápita media que ronda los 190.000 dólares al año. Siendo así, no es de extrañar que el valor medio de las casas sea de casi 2,8 millones de dólares. La del dueño de Microsoft es tan famosa que tiene hasta su propia página de Wikipedia.

Se trata de una mansión valorada en 127 millones de dólares que se llama Xanadú 2.0 en honor a la del personaje principal de la película Ciudadano Kane y que cuenta con 6.000 metros cuadrados construidos.

Residence Of Bill Gates

En 1998, Gates pagó dos millones de dólares por todo el terreno. A los 300 obreros que trabajaron en su construcción les llevó un total de siete años y 63 millones de dólares construir la casa, fabricada con madera de pinos Douglas de más de 500 años de antigüedad.

Tiene un total de 24 baños, 6 cocinas, diversos aparcamientos con capacidad para 23 coches, una biblioteca con 20 sofás y un salón capaz de albergar hasta 150 comensales en una cena o 200 personas de pie en un cóctel. Todo ello, además, de gimnasio con vestuarios separados para hombres y mujeres, baño de vapor, cine de estilo Art Deco con aforo para 20 personas y una casa de invitados de 176 metros cuadrados, por nombrar algunas prestaciones.

Bill Gates House 2015

La piscina (olímpica) también cuenta con su propio edificio y está dotada con un equipo de sonido que permite escuchar música dentro del agua. Aunque más estrafalario aún resulta que la cama elástica también tenga su propio cuarto, con techos de diez metros de altura, o que la arena de la playa se la traigan todos los años del Caribe.

Jeff Bezos

Jeff bezos

Por su parte, Jeff Bezos ha situado su casa en Medina cerca de la sede central de Amazon y a solo un kilómetro de la de Gates. Se trata de un terreno de más de dos hectáreas que alberga una casa principal de más de 2.600 metros cuadrados y una cabaña de campo de 400. Las dos cuentan con 5 dormitorios y 4 baños. La propiedad le costó a Bezos 10 millones de dólares cuando la compró en 1998, está situada a orillas de lago Washington y cuenta con 94 metros de costa.

Aunque el magnate, cuya fortuna valora Forbes en 135.600 millones de dólares, es famoso también por poseer otras muchas y espectaculares propiedades. Por un lado, tiene una villa de estilo español, de más de 20 millones de dólares, en Beverly Hills (Los Ángeles). Esta mansión dispone de siete habitaciones, el mismo número de baños, pista de tenis, piscina, cuatro fuentes y garaje con seis plazas.

Bezos Beverly Hill

Cambiando de estilo, compró un rancho en Van Horn, Texas, de más de 10.000 metros cuadrados y, en 2017, adquirió la casa más grande de Washington DC, que era un antiguo museo textil reconvertido en vivienda de lujo. Por ella pagó 23 millones de dólares, a los que habría que sumar los 12 que les costó reformarla. La reforma supuso construir 11 habitaciones, 25 cuartos de baño, cinco salas de estar, dos ascensores y un solarium.

Bezos Museo

Además, tiene diversas propiedades en los mejores rincones de Nueva York. Empezó en 1999 adquiriendo tres edificios de apartamentos en el Upper West Side. Una construcción, con espectaculares vistas a Central Park, que es un emblema del Art Decó. La última transacción en Manhattan la ha llevado a cabo este mismo año con un ático triplex y los dos pisos vecinos por 72 millones de dólares. Si el empresario uniera las tres viviendas tendría una sola de casi 1.600 m2 y 12 habitaciones.

Está ubicado en la Quinta Avenida y tiene vistas al Madison Square Park, gimnasio, simulador de golf, sala de juegos y una sala de cine. La vivienda también cuenta con varias terrazas al aire libre. Están decoradas con vegetación en las paredes y disponen de camas balinesas, tumbonas para tomar el sol.

jeff bezos

Warren Buffet

Warren Buffett

Warren Buffett es uno de los hombres más rico del mundo. Más concretamente, está posicionado el tercero en la lista de Forbes. Inversor y empresario, su fortuna está valorada en 87.000 millones de dólares. A pesar de ello, vive en la misma casa desde 1958, una mansión, más modesta que las anteriores, situada en un barrio tranquilo de Omaha (Nebraska). Buffett la compró, en su momento, por 31.500 dólares, lo que supone un 0,001% de su patrimonio. Aunque, según datos de Bussiness Insider, en la actualidad estaría valorada en unos 652.600 dólares.

Casa Warren Buffet 4 Jpg 231334169

La vivienda de 610 metros cuadrados, fue construida en 1921 y cuenta con 5 dormitorios, 3 baños, jardín y se encuentra vallada y protegida por cámaras. La razón por la que nunca se ha mudado es, como él mismo declaró en una famosa declaración recogida en un documental de la BBC, porque en ella es feliz y solo se mudaría si pensara que en otro lugar iba a ser más feliz.

Mark Zuckerberg

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La casa de Mark Zuckerberg, el cuarto en la lista Forbes 400, es una propiedad de 500 metros cuadrados, más sencilla que las de Bill Gates y Jeff Bezos. Se encuentra en la exclusiva zona de Edgewood Drive, en Palo Alto (California), a menos de 10 minutos en coche de la sede de Facebook en Menlo Park.

Casa De Mark Zuckerberg 768x576

Zuckerberg la adquirió por 5,6 millones de dólares en 2011. Una compra a la que ha ido sumando las casas que la rodean por motivos de privacidad y para poder decidir personalmente quiénes son sus vecinos. Se trata de cuatro casas por las que pagó 24 millones de dólares.

Interior

Dispone de cinco habitaciones, la misma cantidad de baños y una piscina de agua salada. Aunque una de las partes más atractivas de la casa es su perímetro ya que dispone de un gran jardín al aire libre, ideal para organizar fiestas y eventos.

Mark Zuckerberg House Palo Alto

El interior de la casa se compone de suelos de madera y muebles sencillos y tradicionales, con una decoración bastante austera. No obstante, a pesar de su sencillez, la vivienda cuenta con un pabellón de entretenimiento, chimenea, barbacoa y spa.

Jardin

Amancio Ortega

Amancio Ortega

Según el ránking de las personas más adineradas del mundo que realiza anualmente Forbes, Amancio Ortega es el sexto hombre más rico del mundo y la primera fortuna de España.  La misma publicación ha estimado su fortuna en 63.200 millones de euros. No obstante, el empresario es conocido por su estilo de vida relativamente sencillo. Un reflejo de ello se encuentra en sus propiedades.

Tras su separación de Rosalía Mera en 1986 se instaló en un dúplex con vistas a la playa de Orzán en el barrio de clase media de Zalaeta (A Coruña). Un barrio al que se le conoce popularmente como "Zaraeta" por el gran número de ejecutivos y mandos intermedios de Inditex que viven en él.

Actualmente, Amancio Ortega reside en su casa de O Parrote, también en el centro de A Coruña, donde se celebró la boda de su hija Marta con Carlos Torretta. Se trata de un edificio de cuatro plantas, con una superficie construida de más de 3.000 metros cuadrados, que data de principios del siglo XIX y que fue rehabilitado por el empresario.

Vista Aerea De La Zona Donde Estan La Casa De Ortega Y El Club Nautico Google

Con un singular valor arquitectónico por su amplio frente, sus inmensas puertas de arco y por sus tres galerías, es uno de los edificios que conforman la emblemática fachada marítima de galerías de A Coruña. Además, Amancio Ortega cuenta también con una residencia familiar en el Pazo de Anceis, en una zona rural a las afueras de la ciudad.

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No ha trascendido por cuánto dinero podría haber adquirido el empresario sus propiedades pero la zona de O Parrote es conocida por tener los alquileres más caros en el centro de la ciudad. Según un estudio de la Federación Galega de Empresas Inmobiliarias el precio por metro cuadrado del vecindario casi duplica la media de la ciudad de 7,3 euros.

Fotos | Google Maps, NBC, Wikipedia, The Backyard, Instagram de jmrey42.


          

VuhDo (v3.109-alpha-1)

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Change Log:
--------------------
Version 3.109


Known issues:
-- BfA stat squish cleanup still a work in progress
-- AOE Advice spell equations need complete overhaul
-- Some text providers need changes to better display small numbers
-- Debuff tooltips are currently bugged when using ElvUI
-- Deselect 'VuhDo Options > Panels > Tooltips > Tooltips > Debuffs'
-- In 8.2.0 Blizzard removed the ability to play sounds by file path
-- If you have LibSharedMedia installed make sure it is up to date
-- You may need to reselect your sound options in VuhDo for debuffs


Bugfixes:


Improvements:
-- Added string localization for Korean (koKR)


--------------------------------------------------------------
Version 3.108


Known issues:
-- BfA stat squish cleanup still a work in progress
-- AOE Advice spell equations need complete overhaul
-- Some text providers need changes to better display small numbers
-- Debuff tooltips are currently bugged when using ElvUI
-- Deselect 'VuhDo Options > Panels > Tooltips > Tooltips > Debuffs'
-- In 8.2.0 Blizzard removed the ability to play sounds by file path
-- If you have LibSharedMedia installed make sure it is up to date
-- You may need to reselect your sound options in VuhDo for debuffs


Bugfixes:
-- Fix deletiion of debuff blacklist entries added by spell ID


Improvements:


--------------------------------------------------------------
Version 3.107


Known issues:
-- BfA stat squish cleanup still a work in progress
-- AOE Advice spell equations need complete overhaul
-- Some text providers need changes to better display small numbers
-- Debuff tooltips are currently bugged when using ElvUI
-- Deselect 'VuhDo Options > Panels > Tooltips > Tooltips > Debuffs'
-- In 8.2.0 Blizzard removed the ability to play sounds by file path
-- If you have LibSharedMedia installed make sure it is up to date
-- You may need to reselect your sound options in VuhDo for debuffs


Bugfixes:
-- Real fix for 8.2 bug preventing moving of the VuhDo Options frame


Improvements:


--------------------------------------------------------------
Version 3.106


Known issues:
-- BfA stat squish cleanup still a work in progress
-- AOE Advice spell equations need complete overhaul
-- Some text providers need changes to better display small numbers
-- Debuff tooltips are currently bugged when using ElvUI
-- Deselect 'VuhDo Options > Panels > Tooltips > Tooltips > Debuffs'
-- In 8.2.0 Blizzard removed the ability to play sounds by file path
-- If you have LibSharedMedia installed make sure it is up to date
-- You may need to reselect your sound options in VuhDo for debuffs


Bugfixes:
-- Safer sound playback for profiles created w/ old versions of LSM
-- Workaround for 8.2 bug preventing moving of the VuhDo Options frame


Improvements:


--------------------------------------------------------------
Version 3.105


Known issues:
-- BfA stat squish cleanup still a work in progress
-- AOE Advice spell equations need complete overhaul
-- Some text providers need changes to better display small numbers
-- Debuff tooltips are currently bugged when using ElvUI
-- Deselect 'VuhDo Options > Panels > Tooltips > Tooltips > Debuffs'
-- In 8.2.0 Blizzard removed the ability to play sounds by file path
-- If you have LibSharedMedia installed make sure it is up to date
-- You may need to reselect your sound options in VuhDo for debuffs
-- VuhDo Options frame cannot be moved due to a bug introduced in 8.2


Bugfixes:
-- Fix auto loading of profiles w/o a key layout on spec change


Improvements:


--------------------------------------------------------------
Version 3.104


Known...

Description:
--------------------
Get VuhDo release v3.108 now with support for patch 8.2.5 Rise of Azshara!

To get started read the updated guide over at Icy-Veins.
----

Keep those feature requests and bug reports coming!
Please file GitLab issues to report any bugs or to make feature requests.
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What is VuhDo? VuhDo is a raid monitor similar to CTRaidAssist or Blizzards built-in raid frames. Basically this is about displaying the health of raid members in form of clearly arranged bars. VuhDo is primarily directed to healing classes, but will make use to almost any other class. Moreover several healing spells or other actions can be asserted to mouse clicks on those bars (Click-Heal).

What VuhDo can do:
1.Display all relevant informations about your raid members
-Life,
-Mana, other types of power
-Debuffs
-Range
-Incoming Heal
-Aggro
-Threat
-H