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Дни научного кино ДНК

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Департамент общего образования Томской области информирует о проведении с 25.11 по 29.11 2019 года масштабного просветительского проекта «Дни научного кино ДНК», проводимого по инициативе Фестиваля актуального научного кино ФАНК. Проект поддерживает Министерство науки и высшего образования Российской Федерации.

Проект создан: для того, чтобы познакомить с современным научным кино как можно больше зрителей, пробудить в них интерес к науке, а возможно, и вдохновить на собственные исследования. Партнерами проекта выступают: телеканал «Наука», Русское географическое общество, телеканал «Discovery Channel», Международный фестиваль Зеленого Документального Кино ECOCUP, Международный фестиваль Academia Film.Olomouc, Европейская Академия Научного Кино.

В рамках Дней научного кино в региональной «Точке кипения - Томск» пройдут показы и обсуждение фильмов с экспертами.

Место проведения: Пространство коллективной работы «Точка кипения Томск» пр. Ленина. 26, 2 этаж. (Вход с ул. Аркадия Иванова). Участие бесплатное.

 

Пространство «Точка кипения — Томск» является одной из площадок проведения масштабного просветительского проекта «Дни научного кино ДНК», проводимого по инициативе Фестиваля актуального научного кино ФАНК. Проект поддерживает Министерство науки и высшего образования Российской Федерации.

Проект создан для того, чтобы познакомить с современным научным кино как можно больше зрителей, пробудить в них интерес к науке, а возможно, и вдохновить на собственные исследования. Партнерами проекта выступают: телеканал «Наука», Русское географическое общество, телеканал "Discovery Channel", Международный фестиваль Зеленого Документального Кино ECOCUP, Международный фестиваль Academia Film Olomouc, Европейская Академия Научного Кино.

В рамках Дней научного кино в региональной «Точке кипения - Томск» пройдут показы и обсуждение фильмов с экспертами:

 

Фильм «Изобретая будущее» (12+)

25.11.2019 (понедельник) 18:30-20:30 ч.

Регистрация: https://leader-id.ru/event/29809/

Описание: Документальная лента рассказывает о том, как выглядит современная наука для исследователей, которые совсем недавно встали на путь научных открытий, а как частные инициативы превращаются в рабочие проекты благодаря личным амбициям, усердной работе и поддержке близких людей.

Вместе с тем у создателей фильма получилось провести ещё и социокультурное исследование: на примере своих героев они демонстрируют, как семейные привычки, особенности человека, образ жизни и политическая среда формируют взгляды неравнодушных подростков и. их активную общественную позицию. Наука становится захватывающим приключением c открытым финалом. Сможет ли новое поколение дать человечеству надежду на осознанное будущее?

 

Фильм «Разум, сердце и душа» (12+)

  1. (среда) 18:30 — 20:00 ч.

Регистрация: https://leader-id.ru/event/29840/

Описание: Шесть преподавателей математики si физики желают поделиться красотой своих исследований. Они организуют конкурс с надеждой вдохновить художников на создание новаторских произведений, основанных на современной науке. Для оценки результатов было приглашено жюри из шести экспертов в области искусства, моды и архитектуры.

Можно подумать, что в отличие от красоты математической художественная красота может быть оценена без полного понимания. Неожиданно математическая строгость сменяется художественной, и уверенность учёных в красоте собственных, исследований вступает в противоречие с мировоззрением современных художников.

 

Фильм «Привет, робот!» (16+)

  1. (четверг) 18:30-20:30 ч.

Регистрация: https://leader-id.ru/event/29842/

 

Описание: Роботы-гуманоиды — это новые существа на нашей планете. Они работают на стойках регистрации, в торговых центрах и шеф-поварами ресторанов. Сегодня они приходят и в нашу личную жизнь.

«С искусственным интеллектом вы должны общаться простыми и короткими предложениями», — такой совет Дали Чаку, когда он забирал своего нового робота- партнера Гармонию прямо с заводского конвейера. А на другом конце света, в Токио, сын подарили Сакурайе милого робота Пеппер, чтобы она чувствовала себя менее одинокой.

Как мы будем жить вместе с искусственным интеллектом? Что мы выиграем, что потеряем? Документальный фильм показывает паше будущее.

 

Фильм «Вы доверяете этому компьютеру?» (12+)

29.11.2019 (пятница) 18:30-20:30 ч.

Регистрация: https://leader-id.ru/event/29843/

Описание: «Ваш компьютер знает о вас больше, чем ваша мама», —утверждают эксперты в фильме Криса Пайна «Доверять этому компьютеру?». И к их мнению стоит прислушаться: в фильме смялись изобретатель Илоп Маек, футуролог Реймонд Курцвсйл, режиссёр Джонатан Нолан и многие другие. Фильм без лишних эмоций суммирует всё, что нам известно о плюсах и минусах развития искусственного интеллекта. А он сейчас внедрён везде — от ноутбуков до робототехники, от военных дронов до рекламы в вашем фейсбуке, от которой вы не знаете, куда деться. Человеческие возможности, судя по последним изобретениям, огромны, но еще больше возможности машин, которые теперь могут самообучаться, В фильме Маек говорит: «Однажды все диктаторы умрут, мо их место может занять бессмертный диктатор, от которого не спастись». Режиссёр посвятил киноленту Стивену Хокингу, который утверждал, что однажды человечество окажется под угрозой вымирания из-за своей гонки за супермашинным интеллектом. Или суперинтеллсктуальной машиной»

К участию приглашаются организованные группы (5-7 человек) из числа обучающихся 8-11 классов занимающихся и/или интересующихся научной деятельностью по технологическим, естественно-научным, социальным дисциплинам, а также занимающихся научно-техническим творчеством.

В случае участия организованными группами просьба направить список участников с указанием ФИО, учреждения и класса, а также сопровождающего в свободной форме на эл. почту: boilingpoint.tonisk@vandex.ru

Место проведения: Пространство коллективной работы «Точка кипения - Томск» (пр. Ленина, 26, 2 этаж. Вход с ул. Аркадия Иванова).

Контактное лицо: Валенсия Раевская, +7 (923) 403-87-48

Участие в ДНК сугубо добровольное. Приветствуем мотивированных участников: педагогов, школьников и их родителей. Участие бесплатное.


          

Legacies – “It Will All Be Painfully Clear Soon Enough”

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THE RACE TO CLOSE THE MALIVORE PORTAL — After deciding that leaving town would be for the best, Hope (Danielle Rose Russell) gets pulled back in after Josie (Kaylee Bryant) comes up with a risky plan to close the Malivore portal.  Elsewhere, Alaric (Matthew Davis) and Dorian (guest star Demetrius Bridges) make an alarming discovery […]
          

Over 10,000 evacuated in Turin, Italy over British bomb dropped during WWII

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Preview A discovery of a 500-pound British WWII bomb prompted an urgent evacuation of thousands of people from the historic center of the Italian northern city of Turin, while tens of thousands more were told to stay put.
Read Full Article at RT.com
          

Bee Happy Jumbo Plush

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This Weeks ALDI Finds

each $29.99 *

Description

  • Bear, Dinosaur, Narwhal, Llama or Bulldog
  • These super-cuddly, kid-sized animals are made from 100% Polyester, which makes them great for physical and imaginative play
  • Durable construction allows children to wrestle and play with the animals safely, which encourages the development of motor skills and plenty of fun
  • Ages 3+
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 51297

          

Bee Happy Plastic Animal Set

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This Weeks ALDI Finds

each $6.99 *
25 pieces

Description

  • Dinosaur, Jungle, Ocean or Farm
  • Dinosaur: 17 dinosaurs, 4 rocks, 2 logs and 2 trees
  • Jungle: 17 jungle animals, 2 tree logs, 4 rocks and 2 trees
  • Ocean: 17 sea animals, 4 sea grasses, rock, and 3 coral reef
  • Farm: 16 farm animals, feeding tray, 4 trees and 4 fences
  • Pieces are made of sturdy plastic and are easily stored in the bucket with a handle for portability
  • Sets provide hours of imaginative play
  • Ages 3+
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 57216

          

Bee Happy Truck Transporter with Cars

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This Weeks ALDI Finds

each $18.99 *

Description

  • Includes 14 die-cast cars
  • Carries up to 44 cars
  • Carrier has ample storage on both sides that holds up to 22 cars (44 cars total) and fits most toy car brands
  • Includes built-in ramp in the head of the truck
  • Includes 10 standard die cast cars, 4 premium die cast cars, semi-truck, 2 traffic cones, 2 barricades, stop sign, and traffic barrel
  • Each car has a unique printed design, which is great for any car collector
  • Ages 3+
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 57214

          

Bee Happy 12" Squishmallows

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This Weeks ALDI Finds

each $7.99 *

Description

  • Regular and holiday varieties
  • Collect all 7 styles: Cat, Owl, Unicorn, Dinosaur, Penguin, Moose or Santa
  • Each Squishmallow is 100% Polyester, which makes them soft and cuddly
  • Surface clean only
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 13123

          

Bee Happy 26" Pillowchum

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Upcoming ALDI Finds

each $14.99 *

Description

  • Opens to size 26” x 29” x 8"
  • Red Panda, Dinosaur, Pegacorn, Hamster, Llamacorn or French Bulldog
  • Soft and cozy stuffed pillow is 100% Polyester
  • Opens as a pillow and folds as sitting plush toy
  • Surface clean only
  • Ages 3+
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 44402

          

Bee Happy 18" Doll

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Upcoming ALDI Finds

each $19.99 *

Description

  • Collect all 3: Ballerina, Party Host or Outdoorsy Girl
  • Compatible with leading brands
  • Match your doll with the coordinating ALDI Children's Holiday Pajamas
  • Poseable and has a soft torso
  • Eyes open and close
  • Soft, long hair that can be brushed and styled
  • Ages 3+
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 13392

          

Bee Happy 52 pc Magnetic Tiles

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Upcoming ALDI Finds

each $19.99 *

Description

  • 30 squares and 22 triangles
  • Tiles are assorted colors
  • Encourages creative thinking, color training and coordination
  • Ages 3+
  • Our Bee Happy Beeliefs: We believe that quality products and toys should be accessible to all children. We believe in the joy of accomplishment. We believe in the joy of discovery. We believe in the joy of play. We believe a happy child makes a happy family.
  • Product Code: 8347

          

Used Land Rover Discovery Sport Elmsford NY 10523

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Land Rover Discovery Sport HSE

You can expect a lot from the 2019 Land Rover Discovery Sport With less than 10,000 miles on the odometer, this 4 door sport utility vehicle prioritizes comfort, safety and convenience. Under the hood you'll find a 4 cylinder engine with more than 200 horsepower, providing a smooth and predictable driving experience. Well tuned suspension and stability control deliver a spirited, yet composed, ride and drive The engine breathes better thanks to a turbocharger, improving both performance and economy. The following features are included: an automatic dimming rear-view mirror, a headlight cleaning system, tilt and telescoping steering wheel, power door mirrors and heated door mirrors, blind spot sensor, an overhead console, and leather upholstery. Rear passengers enjoy the seat heating functionality, keeping them warm during the winter months. Audio features include an AM/FM radio, and 17 speakers, providing excellent sound throughout the cabin. Side curtain airbags deploy in extreme circumstances, shielding you and your passengers from collision forces. Our team is professional, and we offer a no-pressure environment. We'd be happy to answer any questions that you may have. Call now to schedule a test drive.


          

Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification

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Application of patient-derived liver cancer cells for phenotypic characterization and therapeutic target identification

Castven, D., Becker, D., Czauderna, C., Wilhelm, D., Andersen, J. B., Strand, S., Hartmann, M., Heilmann-Heimbach, S., Roth, W., Hartmann, N., Straub, B. K., Mahn, F. L., Franck, S., Pereira, S., Haupts, A., Vogel, A., Wörns, M. A., Weinmann, A., Heinrich, S., Lang, H., Thorgeirsson, S. S., Galle, P. R. & Marquardt, J. U., 2019, In : International Journal of Cancer. 144, 11, p. 2782-2794 13 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Primary liver cancer (PLC) ranks among the most lethal solid cancers worldwide due to lack of effective biomarkers for early detection and limited treatment options in advanced stages. Development of primary culture models that closely recapitulate phenotypic and molecular diversities of PLC is urgently needed to improve the patient outcome. Long-term cultures of 7 primary liver cancer cell lines of hepatocellular and cholangiocellular origin were established using defined culture conditions. Morphological and histological characteristics of obtained cell lines and xenograft tumors were analyzed and compared to original tumors. Time course analyses of transcriptomic and genomic changes were performed using next-generation sequencing (NGS). Key oncogenic alterations were identified by targeted NGS and cell lines carrying potentially actionable mutations were treated with corresponding specific inhibitors. PDCL fully resembled morphological features of the primary cancers in vitro and in vivo over extended period in culture. Genomic alterations as well as transcriptome profiles showed high similarity with primary tumors and remained stable during long-term culturing. Targeted-NGS confirmed that key oncogenic mutations such as TP53, KRAS, CTNNB1 as well as actionable mutations (e.g. MET, cKIT, KDR) were highly conserved in PDCL and amenable for individualized therapeutic approaches. Integrative genomic and transcriptomic approaches further demonstrated that PDCL more closely resemble molecular and prognostic features of PLC than established cell lines and are valuable tool for direct target evaluation. Our integrative analysis demonstrates that PDCL represents refined model for discovery of relevant molecular subgroups and exploration of precision medicine approaches for the treatment of this deadly disease. This article is protected by copyright. All rights reserved.

Original languageEnglish
JournalInternational Journal of Cancer
Volume144
Issue number11
Pages (from-to)2782-2794
Number of pages13
ISSN0898-6924
DOIs
Publication statusPublished - 2019

Bibliographical note

This article is protected by copyright. All rights reserved.


          

Proteomic profiling of the thrombin-activated canine platelet secretome (CAPS)

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Proteomic profiling of the thrombin-activated canine platelet secretome (CAPS)

Cremer, S. E., Catalfamo, J. L., Goggs, R., Seemann, S. E., Kristensen, A. T. & Brooks, M. B., 2019, In : PLoS ONE. 14, 11, e0224891.

Research output: Contribution to journalJournal articleResearchpeer-review

Domestic dogs share the same environment as humans, and they represent a valuable animal model to study naturally-occurring human disease. Platelet proteomics holds promise for the discovery of biomarkers that capture the contribution of platelets to the pathophysiology of many disease states, however, canine platelet proteomic studies are lacking. Our study objectives were to establish a protocol for proteomic identification and quantification of the thrombin-activated canine platelet secretome (CAPS), and to compare the CAPS proteins to human and murine platelet proteomic data. Washed platelets were isolated from healthy dogs, and stimulated with saline (control) or gamma-thrombin (releasate). Proteins were separated by SDS-page, trypsin-digested and analyzed by liquid chromatography and tandem mass spectrometry (MS). CAPS proteins were defined as those with a MS1-abundance ratio of two or more for releasate vs. unstimulated saline control. A total of 1,918 proteins were identified, with 908 proteins common to all dogs and 693 characterized as CAPS proteins. CAPS proteins were similar to human and murine platelet secretomes and were highly represented in hemostatic pathways. Differences unique to CAPS included replacement of platelet factor 4 with other cleavage products of platelet basic protein (e.g. interleukin-8), novel proteins (e.g. C-C motif chemokine 14), and proteins in relatively high (e.g. protease nexin-1) or low (e.g. von Willebrand factor) abundance. This study establishes the first in-depth platelet releasate proteome from healthy dogs with a reference database of 693 CAPS proteins. Similarities between CAPS and the human secretome confirm the utility of dogs as translational models of human disease, but we also identify differences unique to canine platelets. Our findings provide a resource for further investigations into disease-related CAPS profiles, and for comparative pathway analyses of platelet activation among species.

Original languageEnglish
Article numbere0224891
JournalPLoS ONE
Volume14
Issue number11
ISSN1932-6203
DOIs
Publication statusPublished - 2019

          

South Country Central School District Board Notes – May 22 Business Meeting

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At the commencement of the May 22 Board of Education business meeting, President Cheryl A. Felice called for a moment of silence in recognition of Memorial Day and for those who gave their lives to assure our rights as Americans. The first order of the meeting was for district clerk Christine Flynn to administer the oath of faithful performance to Cameron Trent, who was voted as a trustee to the Board of Education for a two-year term, ending on June 30, 2021. Mr. Trent said being elected to the Board has been a “humbling experience” and that he is ready to get to work. The meeting’s agenda was followed out of order to accommodate presentations, including Kreamer Street Elementary School students’ report about the school’s new STEAM Lab. Members of the Kreamer Kingdom STEAM Lab Commission were on hand, but student representatives from grades K-3 explained to the trustees and Superintendent of Schools Dr. Joseph Giani what it has meant to have the pilot program in place. In addition, the Board and Kreamer Street Principal Sean Clark honored science teacher Gina Benzie, who was named a 2019 recipient of the Suffolk Section of the Science Teachers Association of New York State (STANYS) Elementary Level Science Teacher of the Year for having promoted the enhancement of science education with distinction. During Dr. Giani’s report, he congratulated Fine Arts Chairperson Suzette Fandale and Music Chairperson James Uzzi on the excellent Districtwide Fine and Performing Arts Show. Dr. Giani and the trustees congratulated the students on their excellent work, and trustee Chris Picini added that the annual event is a “tradition” with his family. Dr. Giani and President Felice also congratulated trustee election candidates Melissa Aruta, E. Ann Hayes and Clyde Parker who were elected to the Board of Education, commencing July 1, 2019 for a three-year term. Dr. Giani also announced that the 2019-2020 proposed budget and additional propositions were overwhelmingly approved and thanked the community for their support. Center for Environmental Education and Discovery Co-Founders Rebecca Muellers and Tom Pelletier also started a dialogue about the organization’s school program opportunities. The environmental organization is interested in being a future resource for the district. The trustees also approved the Board meeting calendar for the 2019-2020 school year, as well as nine probationary appointments. In other business, the Board approved a Tax Anticipation Note (TAN) resolution, not to exceed $21 million, which will allow the District to borrow funds for the purpose of covering expenses in the short-term, until the receipt of tax monies from the Town, which is expected to begin in late December 2019. The next Board of Education meeting will be held on June 12.
          

Professions: Revit MEP Senior Solutions Specialist - Houston, Texas

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We have been retained to lead a search for a Revit MEP Senior Solutions Specialist. You can be based in the Houston area or anywhere in the US that is near a major airport. Position Summary This role is a trusted technical advisor to our clients in providing technical expertise and strategic insight for a diverse Architecture, Engineering, Construction, and Building Owner customer base. Examples of services include BIM and Revit Consulting, Training, Mentoring, Solutions Development, Discovery, Opportunity Qualification, and Workflow Analysis and Design. Product knowledge of applications in the Autodesk AEC Collection and BIM 360 is desired as well as specific knowledge of BIM requirements, BIM processes and workflows, and Revit. While this is primarily a technical services provider position, you will be expected to provide pre-sales support for our team of Account Advisors as well. This role will be centered primarily on servicing our Mechanical, Electrical and Plumbing (MEP) customers, and will require experience in that field. Attraction for this position -- Deepen and increase the value of your skills-- Work with the latest technology and sophisticated users-- Work from a home office most of the time except when visiting customers-- Company is committed to ongoing training and certification-- Progressive team culture and better quality of life-- Stable, growing company with strong leadership Desired Experience and Qualifications: 4+ years of experience using Autodesk Revit MEP Strong engineering knowledge and experience in HVAC design Experience with AutoCAD, AutoCAD MEP, Navisworks is not required but is a plus Travel 25-35% may be required, but you will also use remote desktop sharing technologies to deliver consulting services and pre and post-sales support remotely whenever possible. Next Steps This is a fun, upbeat high-tech environment with sharp co-workers. For priority consideration please submit your resume. Qualified candidates will be sent additional information including the company name. All inquiries will be kept in confidence. This will be an outstanding opportunity for the right person! ()
          

SCCSD Board Notes Feb. 27 Meeting

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The Board of Education held its second business meeting of the month, commencing with a hearty congratulations to the boys basketball team, who won the league championship, and for the flawless high school performances of “Rent.” During the Superintendent report, Dr. Joseph Giani reminded the community that voting times for this year’s school budget and trustee election on May 21 have been expanded to 6 a.m. to 9 p.m. He also reported that the Frank P. Long Intermediate School window and door project is in full swing with completion set for April. The Board approved the consolidated 2019-2020 school calendar, which will have a start date for the new school year on Sept. 4, two whole weeks off at the winter recess and one snow day built in. March 25 is the start of the District’s pre-kindergarten program registration. Information on how to register is on the District website. Trustee Di Santo said she would like to see members of the community take a closer look at becoming involved in the District’s advisory committee meetings scheduled for March 4-7. The next round of meetings will be held on June 3-6 for finance and facilities, health and safety, strategic planning and teaching and learning. Locations and times are posted on the District website. President Felice discussed inviting CEED, the Center for Environmental Education and Discovery, to meet with the superintendent and discuss joint programming. Trustee Picini asked the District to educate the community about the Momo Challenge. Halfway through YouTube videos for children like “Peppa Pig” and “Fortnite,” a scary image pops up which encourages children to harm themselves. The Board agreed parents should receive communication about this menacing and potentially dangerous challenge, and a letter from Dr. Giani has since been posted to the website. Dr. Anthony Griffin said he had the opportunity to visit Brookhaven Elementary School and saw three things: a school of love, laughter and learning.He noted that even though the state has labeled the school one that needs improvement and support, this is not what he saw on his tour. “This is not who we are,” he said, and he appreciates the letter that was sent to the staff from Dr. Giani. High school teacher Gaetano Greco and school counselor teaching assistant Daniel Jarmon were recognized for their selfless efforts in cleaning off staff cars of snow during a recent snow storm. The next business meeting will be held on March 13 at 7:30 p.m. with a budget presentation on curriculum and instruction.
          

SCCSD Board Notes Feb. 6 Business Meeting

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The South Country Board of Education met for its first business meeting of the month on Feb. 6 with much discussion about the impending 2019-2020 district budget. During the superintendent’s report, Dr. Joseph Giani announced that he and Board President Cheryl A. Felice attended the 15th annual Legislative Breakfast held at Longwood High School on Feb. 2. He also announced that the district will participate in the Children’s Writing and Illustration Competition and Crayon Collection Drive, sponsored by the CEED Center for Environmental Education & Discovery and in conjunction with the second annual Bellport and Brookhaven Children’s Book Festival. Dr. Giani also congratulated the 15 student wrestlers from the high school varsity wrestling team who qualified to compete in the Suffolk County Section II Tournament, being held at Suffolk County Community College on Feb. 9-10. Assistant Superintendent for Finance and Management Services Dr. Sammy Gergis gave an overview of the tax levy limit and revenue during the district’s second budget presentation. He noted that in the first governor’s budget run, the district stands to receive $56.7 million in aid, which is approximately $419,000 less than last year. Dr. Gergis also calculated through an eight-step process the projected tax levy for the 2019-20 school year, totaling $62,240,685, which is a 3.36 percent increase and $2,022,996 more than last year. At this time, the projected 2019-20 spending plan totals $129,171,139. He also noted that these numbers will change throughout the budget process. The Board and Dr. Giani also discussed the budget brochure in terms of its compliance with the Voting Rights Act. The Board also passed a Capital Reserve Resolution to expend no more than $2.3 million from the existing 2016 Capital Reserve Fund to replace the exterior vestibule and all windows at Kreamer Street Elementary School. The resolution, which will not affect the taxpayer, must be approved by voters and will be placed on the ballot during the 2019-20 district election to be held on May 21. The Board will meet on Wednesday, Feb. 27, at 7:30 p.m. when Dr. Gergis will give a budget presentation on general support, operations and maintenance, security, utilities, transportation, employee benefits, debt service, fund transfers and capital expenditures.
          

Legal: Litigation Attorney 2+ years (9895) - Houston, Texas

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Job Description:Prominent Houston area law firm has a fantastic opportunity for an experienced litigation attorney to join their firm. Qualifications:Candidates must have a strong academic background, good writing skills and 2-5 years of litigation experience. Legal research, discovery, mediations, client/witness interviews, and trial preparation experience required. Strong organizational, reasoning, research and persuasive writing skills required. Excellent written and verbal communication skills. Sound judgment. Attention to detail. Courtroom experience (both motion practice and trial). Flexibility, composure and the ability to prioritize and handle urgent tasks when needed as well as the ability to remain composed and professional while dealing with complex matters. Commitment to professional ethics and client confidentiality. Strong client-service skills. Ability to work both independently and as part of a team. The firm handles commercial litigation, insurance defense, personal injury, oil & gas, and appeals. Experience in any of these areas is strongly preferred. ()
          

Empire State Grant awarded to South Country CSD

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The district, in conjunction with the Economic Opportunity Council of Suffolk, Inc. was awarded an Empire State Afterschool Program grant. Totaling $560,000 a year for four years, the grant will support an afterschool program at Bellport Middle School for 300 students in grades 6-8 and will run three hours a day for five days a week. The opening date of the program is projected for later this fall. In addition, 50 high school students will be provided afterschool programming through the Boys and Girls Club of the Bellport Area. “The district appreciates this generous grant, which will provide a much-needed service to students in our community and which will fill a gap for students and their parents who need alternatives for afterschool hours,” Superintendent of Schools Dr. Joseph Giani stated. Economic Opportunity Council of Suffolk, Inc. Director of Youth and Adolescent Services Cynthia Amato explained that the grant will provide vocational, recreational and educational preventative programming. As an Economic Opportunity Council of Suffolk, Inc. partner, the Suffolk County Police Department will also provide education on violence prevention and the risks of drug use and addiction. In addition to a designated homework hour with tutors in core subjects, participants will select from a host of activities, including science, technology, engineering and mathematics (STEM), cooking, dance, music/audio club, music/DJ mix club, special events for students and families, and social-emotional and healthy living activities. Through the Leaders of the Future/STARS (Students Taking an Active Role in Society) clubs, participants will also learn leadership skills and take on community service projects. SAVVY Me program activities will also promote self-discovery and understanding. “With increased afterschool participation through enrollment, we aim to improve academics and attendance, as well as foster parental involvement,” Amato said.
          

Board of Education Commendations

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Bellport High School Students and Varsity Girls Volleyball Coach Larry Auth were recognized at the January 8th Board of Education meeting in honor of their achievements in Art and Athletics.. Superintendent of Schools, Joseph Giani and Board President, Chris Picini, presented certificates to the following students and Coach Auth: Art Danielle Rose, recipient of the South Bay Art Association Scholarship Award. Rachel Saur, recipient of the Brookhaven National Laboratory Discovery Award. Athletics Mariah Jno-Charles - All County, Girls Cross Country Connor Cipp - All County, Football Arella Guirantes - All County, Volleyball Connor Haverty - All County, Football Chris Swenson - All County, Boys Cross Country Athletics - NYSAHPERD Suffolk Zone Award Matt Posch - NYSAHPERD Suffolk Zone Award Nina Puglisi - NYSAHPERD Suffolk Zone Award Girls Varsity Volleyball Coach Larry Auth - 300 Victories for Girls Varsity Volleyball
          

Bellport High School Art Department News

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Ms. Suzette Fandale, Art Chairperson of the South Country Central School District is pleased to announce that several Bellport High School students displayed their artwork at the opening to the 2013-2014 show season. A reception was held recently at the Bellport Community Center where students from 11 local high schools competed in the 26th Nita Elder Student Scholarship Art Exhibit. Over 200 works were displayed. Two Bellport High School students received awards. Danielle Rose received the South Bay Art Association Scholarship Award and Rachel Saur was the recipient of the Brookhaven National Laboratory Discovery Award.
          

The Elderflower Fields magic grows with Elderflower Field Midlands in 2020!

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Elderflower Fields Midlands, 29-31 May 2020, Stanford Hall, Leicestershire. WIN a Family Weekend Ticket to Elderflower Fields Midlands at the bottom of this post worth £300! Elderflower Fields is all about families trying new things and after eight years of fantastic feedback the So Sussex team are excited to take on the challenge of a second wild family adventure. 2020 will see the launch of Elderflower Fields Midlands at the stunning rural location of Stanford Hall. Nestled on the edge of the river Avon this Grade 1 listed stately home is surrounded by 700 acres of gardens and grounds and the perfect location for the Elderflower Fields magic to grow. Lying where Leicestershire meets Warwickshire and Northamptonshire in the heart of England, Stanford Hall offers the perfect spot for families to escape and discover the delights of this unique part of the country. So Sussex are working with local activity providers, performers, nature experts and food vendors to build a rich programme of sports, arts and environmental content for children that Elderflower has become so well known for. A weekend of discovery, activity and family adventure Elderflower Fields is now recognised as one of the leading family festivals in the […]

The post The Elderflower Fields magic grows with Elderflower Field Midlands in 2020! appeared first on Mini Travellers - Family Travel & Family Holiday Tips.


          

7 Ways You Know You're Listening to Holy Spirit and Not a Religious Spirit

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"Yet many of the rulers also believed in Him. But because of the Pharisees they did not confess Him, lest they be put out of the synagogue. For they loved the praise of men more than the praise of God" (John 12:42-43).

When Jesus revolutionized His nation with the gospel of the kingdom, He was continually questioned and criticized for His visionary initiatives and unorthodox methods. The Pharisees were the politically correct referees who sought to silence His voice and penalize any advancement of His message.

Knowing that their power and influence were losing ground, their religious mindsets could not comprehend or celebrate the very truths that could set them free from their own man-made bondage.

It is just like the accuser of the brethren to threaten and attack anyone who exposes his lies and demonstrates the true nature of our heavenly Father. Our spiritual adversary seeks to use control, fear and condemnation in order to keep us trapped in our flesh and disconnected from the life-giving power of God's Spirit.

This religious spirit is still active today, speaking into the ears of many unsuspecting believers, trying to block any kingdom advancement and fresh expression of the Holy Spirit. Preying on our fears and self-doubts, this demonic influence will stop at nothing to keep us bound to religious systems and the expectations of man.

This spirit is manifesting again today, not only in our national politics, but in many of our church pulpits and social media platforms. This counterfeit authority is still speaking, trying to draw us away from all that the Father is accomplishing in this hour. The enemy resists any true work of the Spirit and subverts any attempts at bringing the supernatural realities of heaven to earth.

It is the Holy Spirit who we must recognize and embrace if we are to partner with heaven's purposes and see radical transformation happen in our culture. It is the Holy Spirit who will lead us into truth and keep us on the path to victory. It is His voice that we can trust to rightly discern the Father's activities and discern the enemy's schemes.

"But when the Spirit of truth comes, He will guide you into all truth. For He will not speak on His own authority. But He will speak whatever He hears, and He will tell you things that are to come" (John 16:13).

The first step in getting free of any religious spirit is to recognize its presence and purpose. If we understand the redeeming nature of the Father's heart and His highest purposes for our lives, we can rightly discern which voice to listen to in order to open wide the gates for the King of glory to come in.

Prayerfully consider these comparisons and see if you recognize any pattern in your own life:

  1. The religious spirit is like an older brother who follows you around, criticizing your every move and whispering endless doubts that cause you to shrink back in fear. The Holy Spirit is like a loving father who is always two steps ahead, taking your hand and gently leading you on a path of discovery.
  2. The religious spirit gets bent out of shape when the rules aren't followed. The Holy Spirit gets excited when creative expression imagines the possibilities.
  3. The religious spirit berates you for missing the mark. The Holy Spirit inspires you to aim higher next time.
  4. The religious spirit tells you to "stay in the lines!" The Holy Spirit tells you to "go explore!"
  5. The religious spirit wants credit. The Holy Spirit celebrates others.
  6. The religious spirit debates everything you do. The Holy Spirit dares you to climb higher.
  7. The religious spirit is a task master that is never satisfied with your efforts and always asking for more. The Holy Spirit is your greatest cheerleader, drawing out the best in you, even when you make mistakes.

Your journey is meant to be one of freedom, joy and a never-ending sense of wonder and awe. Even through the trials, setbacks and personal weaknesses, the Holy Spirit always sees a way through and will empower you to keep moving.

Your destiny is ahead of you, not behind you. It's not about "adding up," but jumping in! It's redemption, not religion, that brings life to the dead and wholeness to the broken.

As we determine to follow Jesus' example and listen to the Holy Spirit instead of a politically correct religious spirit, we can be assured of fulfilling the Father's purpose.

In the end, it's not whether or not we get it "right." It's about who we travel with and discovering the endless possibilities of heaven inside of us that the flesh can never reach.

"So then, beloved ones, the flesh has no claims on us at all, and we have no further obligation to live in obedience to it. For when you live controlled by the flesh, you are about to die. But if the life of the Spirit puts to death the corrupt ways of the flesh, we then taste his abundant life. The mature children of God are those who are moved by the impulses of the Holy Spirit" (Rom. 8:12-14, TPT). {eoa}

Wanda Alger is a field correspondent with Intercessors for America. She ministers with her husband in Winchester, Virginia. Follow her blog at wandaalger.me.


          

World AIDS Day: Spain makes research breakthrough in fight against HIV virus

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As events take place on World AIDS Day on Sunday to highlight the global fight against the HIV/AIDS epidemic, Spanish doctors have made an exceptional discovery that could revolutionise research. Roughly 150,000 people are infected with HIV in the European country, which has been recognised in medical journals for important contributions to the fight.   is also one of the most advanced in the fight against HIV.
          

Joyn+ startet heute

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Heute startet Joyn Plus, der Premiumservice des Streamingdienstes Joyn, den ProSieben.Sat1 und Discovery im Juni in einem 50:50-Joint-Venture ins Leben gerufen haben: Joyn Plus startet mit Originals und Kampfpreis. Bisher ging ja nur schauen mit Werbung, ein Account mit Abo schafft nun Abhilfe. Das Abo soll 6,99 pro Monat kosten und liegt damit deutlich unter […]
          

Dexphot malware uses fileless techniques to install cryptominer

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Microsoft Corporation yesterday revealed its discovery of a polymorphic malware that uses fileless techniques to execute a cryptomining program on victimized machines. Dubbed Dexphot, the malware was first observed in October 2018 when Microsoft detected a campaign that “attempted to deploy files that changed every 20 to 30 minutes on thousands of devices,” according to…

The post Dexphot malware uses fileless techniques to install cryptominer appeared first on SC Media.


          

THE NEXT TITAN – Nigeria’s Entrepreneurial Reality TV Show

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The Next Titan Reality TV Show - Elsieisy Blog

For so many years, the media space in Nigeria has been populated to the point of over saturation with unwholesome and unhealthy content which do not particularly strive to discover, develop and harness the right value system, culture and principles which lend to a quest for true self-discovery with a potential to be a catalyst […]

Elsieisy's blog


          

Mobile Fix - November 29

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Sports

In a world where content gets more and more important Sports has a special role. Live sports remain an anchor for broadcasters, although we are seeing highlights (especially goals) grow in importance as social content. Axos report on the new players gaining ground, with DAZN doubling subscribers and ESPN+ seems to be doing well too. The Athletic has hoovered up talent in the UK and this interview with the founder is good insight into building modern media brands.

Evidence of the rising value of sports comes from PE firm Silver Lake investing $500m into Man City owners - and the deal was brokered by Talent Agent Ari Emanuel

The logic behind these high valuations is the belief that more viewers will watch the games online and it’s no surprise that UEFA are exploring a move into Champions League streaming. Just as Netflix and Disney have gone DTC, the football model of selling to broadcasters looks to be reaching a ceiling. And the ultimate prize is pay to view games; My Sky subscription is good value in December with 3 Leeds games but big clubs - like Leeds - know they would profit from going direct.

China

I am convinced that Live Selling is going to be huge for DTC. QVC is an amazing business and in China we are seeing this take off - although sometimes there are problems. With discovery for DTC a huge issue, could this be a solution? Is anyone doing this in the UK or US?

Transition...Read More

          

Litigation Associate Attorney - New Mexico-Albuquerque

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Albuquerque office of our client seeks litigation associate attorney with 3-6 years of experience. The candidate should have significant experience drafting pleadings, dispositive motions, and discovery. Experience in the following practice areas will be given preferential consideration: commercial litigation, consumer finance and creditor rights, mortgage lending and servicing, real estate, bankruptcy, and banking.The candidate must possess strong research and writing skills.
          

Egypt unveils mummies of lion cubs, cats and crocodiles in rare find

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Discovery of lion cubs and cat mummies in Egypt sheds light on ancient animal worship.
          

Building a Next-Gen Sous Vide Machine for Today’s Kitchen

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For this episode of Art of the Kickstart, we caught up with Zalmi Duchman, the CEO of Mellow Duo. After finding success in the food tech industry for over 15 years, specifically in that of fresh meal delivery services, learn how and why Duchman invested in Mellow and guided its development into what it is today. Also, learn why he decided to use Kickstarter to help bring Mellow’s second-generation product to life. Topics Discussed and Key Crowdfunding Takeaways How Duchman evolved the brand and the product after learning about it via ProductHunt, eventually investing in the business Why he chose Kickstarter to grow the business while maintaining Mellow’s original community What led to the campaign’s initial success within the first 24 hours of launch How Duchman discovered Enventys Partners and why he chose them as their industry-specific crowdfunding marketing agency Links Mellow Duo on Kickstarter Good to Great Sponsors Art of the Kickstart is honored to be sponsored by The Gadget Flow, a product discovery platform that helps you discover, save, and buy awesome products. The Gadget Flow is the ultimate buyer's guide for cool luxury gadgets and creative gifts. Click here to learn more and list your product - use coupon code ATOKK16 for 20% off! Art of the Kickstart is honored to be sponsored by BackerKit. BackerKit makes software that crowdfunding project creators use to survey backers, organize data, raise additional funds with add-ons and manage orders for fulfillment, saving creators hundreds of hours. To learn more and get started, click here. Transcript
          

Как оптимизировать TCP/IP - соединения

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Привет уважаемые читатели блога. Оплата соединения с Интернет любима  всеми провайдерами, которые не могут  обеспечить надлежащую скорость обмена. Если бы  все злоключения ограничивались одной скоростью (или  полным отсутствуем таковой). Так нет же – соединение может быть нестабильным, часто обрываться, а то и не работать совсем - некоторые сайты могут не грузиться, ругаясь на загадочную ошибку "TTL Bug". Конечно, лучше всего – сменить провайдера, но это не всегда возможно.
Поэтому лучше уж самим настроить  параметры  TCP/IP - соединения  на  максимальную
производительность, что дает прирост скорости обмена и избавляет от большей части разрывов. Остаются лишь фатальные сбои и зависания самого провайдера, побороть которые с клиентской стороны принципиально невозможно.
О параметрах  конфигурации TCP/IP для Windows XP читайте  далее

Первое с чего нужно начать это - попытаемся устранить разрывы TCP - соединений
(не путать с разрывами модемных соединений!). Они довольно многочисленны и разнообразны, а причиной их возникновения может быть и провайдер, и один из маршрутизаторов в длинной цепочке передачи пакетов, и сам удаленный сервер, с которым, собственно, и установлено соединение.
И начнем с провайдера - модем не бросает трубку, но все установленные соединения вдруг обрываются и после этого ни к одному серверу подключиться не удается.
Положение спасает лишь реконнект – отключение от Интернет и повторный вход вновь.
Мало того, что это медленно, к тому же есть риск нарваться на глухую "стену", если
освободившийся телефонный номер мгновенно займет другой клиент (особенно если у провайдера острый недостаток входных номеров).
Такие разрывы могут происходить и эпизодически, и по несколько раз в час, а то и в минуту.
Причина их возникновения, скорее всего, в том, что у провайдера неправильно настроен DHCP - сервер.
Тот самый, что выдает пользователям IP - адреса, потому что он выдает их не насовсем, а
на некоторое время. Если клиент (точнее операционная система)
по каким-то там причинам  не успеет продлить срок аренды, его IP-адрес будет отнят.
А когда же, наконец, клиент "проснется" и пошлет повторно запрос DHCP - серверу, тот выдаст еще один IP - адрес, и вроде бы все ничего, только вот не хочет понимать  Windows этого. Она ожидает получения IP - адреса всего лишь один разна стадии подключения к
провайдеру. Получить-то IP - адрес Windows  получает, но вот включить его в таблицу маршрутизации "забывает", и ни один отправляемый пакет не может уйти дальше своего компьютера. И тут уже надо самому исправлять положение.

Вначале необходимо в сеансе MS - DOS запустить утилиту ipconfig


(входит в штатную поставку Windows) и посмотреть какой у нас IP - адрес.
Если он выглядит как "0.0.0.0" – значит, DHCP-сервер - висит глухо.
Если же IP равен "127.0.0.1" – сети напрочь нет, и тут что-то посерьезнее.
А вот любое другое значение указывает на верный IP - адрес, который необходимо добавить в  таблицу маршрутизации, передав его утилите route из штатной поставки Windows следующим образом: "route.exe ADD 0.0.0.0 MASK 0.0.0.0 Ваш IP METRIC 1".

Попробуйте установить соединение с каким-нибудь сервером, – теперь все должно заработать.
Однако восстановить соединение без реконнекта - это только полдела.
Хорошо бы устранить и причину этих разрывов - ведь не все же сервера поддерживают докачку, а частые разрывы создают большие проблемы.
 Приходится выкручиваться самостоятельно, но на клиентской стороне очень мало, что можно
сделать, да и то, только если Вы не разработчик или программист..

Еще один неприятный момент это - ошибка "TTL bug", приводящая к
невозможности установки соединения. Дело в том, что во избежание засорения сети "Летучими Голландцами", то есть, попросту говоря, зацикленными пакетами, каждый из них имеет ограниченный срок существования, указанный в заголовке и измеряемый количеством промежуточных узлов, которые может посетить пакет. Если пакет не будет доставлен за это время, он "прибивается" очередным маршрутизатором c посылкой отправителю соответствующего  уведомления.

Чем больше транзитных узлов расположено между отправителем и получателем, тем дольше пакеты добираются из одного конца в другой. К счастью, время жизни пакета (аббревиатура TTL так и расшифровывается Time To Live – время жизни) очень легко изменить: запустите Редактор Реестра, (Пуск - Выполнить - regedit)


предварительно скопировав (сохранив)  сам реестр, и откройте ветвь:
HKEY_LOCAL_MACHINE \ SYSTEM \CurrentControlSet \ Services \ Tcpip \ Parameters \ DefaultTTL - для ОС Windows NT\2000




и HKEY_LOCAL_MACHINE \ System \ CurrentControlSet \ Services \ VxD \ MSTCP \ DefaultTTL   для Windows 9x, – она-то и управляет сроком жизни пакетов. По умолчанию он равен 32 узлам(я поставил 64, как видите), но, как показывает практика, в некоторых случаях этого явно недостаточно и стоит увеличить его, по крайней мере, вдвое. (Можно и больше – но от этого лучше не станет, хотя и хуже – тоже). После внесения изменений в реестр следует перегрузиться, заново войти в сеть и проверить, возымело ли это какое-то действие.

Еще один момент это надо включить опцию с интригующим названием:
Распознавание Черной Дыры – "Black Hole Detect".
Для чего она нужна? А вот для чего –  Windows, стремясь увеличить скорость передачи данных, пытается вычислить  максимальный  размер  пакета,  который  бы  обрабатывался  пересылающими  его маршрутизаторами без разрезания. 
Разрезание (или, говоря профессиональным языком, фрагментация) ощутимо снижает скорость соединения, особенно если пакет дробится на две неравные половины.
Например, пусть компьютер клиента пытается передать пакет размером в 576 байт,
но один из маршрутизаторов в цепочке "умеет считать" только до 512, и разрезает пакет на два, причем во второй попадает "хвостик" из 64 байт, плюс заголовок, занимающий от 40 и более байт. В итоге – КПД второго пакета составит всего лишь 50%, что очень нам не нужно
Какая у Вас скорость передачи данных читайте далее

Если Windows видит, что избежать фрагментации не удастся, она уменьшает размер пакета так, чтобы он без проблем прошел сквозь все маршрутизаторы одним куском. Но не проще было бы сразу задать минимальный размер? Нет, и вот почему: чем меньше пакет, тем выше накладные расходы на его пересылку (заголовок тоже ведь занимает место) и тем больше пакетов требуется переслать для передачи того же объема информации.

Умение Windows подбирать максимальный размер нефрагментируемого пакета всем хорошо известно, да только вот – не всегда это работает. Некоторые, не слишком демократичные маршрутизаторы, получив слишком длинный (по их мнению) пакет с пометкой "не фрагментировать", прибивают его на месте безо всяких уведомлений! Windows же, не подозревая, что посланный ею пакет погиб, ждет отклика от сервера.
Долго ждет… А затем, так и не дождавшись, вновь посылает тот же самый пакет. И все повторяется! Вот этот-то маршрутизатор и называется "Черной дырой".

Запустите "Редактор Реестра" и откройте ветвь HKEY_LOCAL_MACHINE \ System \ CurrentControlSet \Services \ VxD \ MSTCP для Windows 95\98 и
HKEY_LOCAL_MACHINE \ System \ CurrentControlSet \
Services \ Tcpip \ Parameters для Windows NT\2000.

Найдите или при необходимости создайте двоичный параметр:  
PMTUBlackHoleDetect для Windows 95\98 и
EnablePMTUBHDetect для Windows NT\2000.


Теперь присвойте ему значение "1" и перегрузитесь.

                                   Теперь об оптимизации соединения.

Автоматическое определение подходящего размера пакета не всегда увеличивает скорость соединения, нередко оно ее уменьшает, подчас весьма значительно, –автоматическое определение занимает какое-то время, увеличивая накладные расходы и снижая КПД.
Имеет смысл попробовать найти оптимальное значение вручную.

Первым делом необходимо указать Windows, что требуется использовать не максимально возможный, а заранее оговоренный размер пакета.
Для этого установите значение ключа PMTUDiscovery (EnablePMTUDiscovery) в ноль.


Затем задайте желаемый размер пакета.
По умолчанию он равен 576 байтам – это значение по стандарту должны поддерживать все маршрутизаторы, – да только кто эти стандарты соблюдает? Вот и встречаются узлы, обрабатывающие пакеты размером не более 512, 522, 556,… байт.
В принципе, можно поставить 500 и не мучатся с проблемой выбора, но разве не интересно самому подбором байтов оптимизировать соединение до конца?
От чего зависит скорость TCP/IP-соединений читайте  далее

Размер пакетов для Windows 95\98 задается ключом MaxMTU, находящимся в той же самой ветке реестра,что и предыдущие ключи.
С Windows NT\2000 посложнее: чтобы выяснить местоположение ключа MTU
необходимо определить идентификатор используемого адаптера.
Перечень всех адаптеров компьютера содержится в ключе Adapters ветки HKEY_LOCAL_MACHINE \ System \ CurrentControlSet \ Services \ Tcpip\ Parameters.  
Как правило, большинство персональных компьютеров обходятся лишь одним адаптером
контроллером удаленного доступа (нет, это не плата расширения, это драйвер такой) и
проблемы выбора нужного идентификатора не стоит.
Идентификатор же, – это такое длинное малопонятное число, например: 20692835-7194-467A-A2DC-0FAE23F0A70D.
Запоминаем (записываем) его и открываем ветку HKEY_LOCAL_MACHINE \ SYSTEM \ CurrentControlSet \Services \ ИдентификаторАдаптера \ Parameters \ Tcpip

(В Windows 2000HKEY_LOCAL_MACHINE \SYSTEM \ CurrentControlSet \ Services \  Tcpip \ Parameters \Interfaces \ ИдентификаторАдаптера


Среди всего прочего здесь должен находиться только что запомненный идентификатор адаптера, а в нем – ключ MTU, содержащий в себе максимальный размер пакета в байтах. Если такого ключа нет, его необходимо создать.
Тип ключа MTU в обоих случаях соответствует двойному слову (DWORD).

Еще один параметр оптимизации -- размер TCP - окна.
Чем "шире" окно, тем выше производительность, но, в то же время, больше издержки на повторные пересылки: случись какой сбой, – не до конца заполненное окно очистится и придется его "набивать" с самого начала.
К тому же, баловство с неумеренно широкими окнами часто приводит к образованию заторов в сети: промежуточные узлы не успевают обрабатывать сыплющийся на них поток пакетов и начинают жутко тормозить. Причем, не только у виновника несчастья, но и у других ни в чем не повинных пользователей.
Ширина TCP-окна должна быть кратна размеру пакета за вычетом длины заголовка и превосходить его по крайне мере в четыре-шесть раз. В некоторых случаях наивысшая производительность достигается при ширине окна в 10 х -12 х (где х – размер пакета без заголовка, называемый так же "квиком").
 Размер заголовка непостоянен и варьируется от 40 до 60 байт, – не забывайте об этом при
поиске оптимальной ширины окна!

Для изменения размеров окна откройте ветвь реестра:
HKEY_LOCAL_MACHINE \ System \
CurrentControlSet \ Services \ VxD \ MSTCP для Windows 95\98 
и HKEY_LOCAL_MACHINE \ System \CurrentControlSet \ Services \ Tcpip \ Parameters
для Windows NT\2000. Найдите или при необходимости
создайте двоичный параметр (двойное слово, DWORD):
DefaultRcvWindow-- для Windows 95\98
и TcpWindowSize для Windows NT\2000.



Присвойте ему желаемое значение (например "3680", если размер пакета, заданный ключом MTU, равен 500 байт: (500 – 40) * 8 = 3/600) и перегрузитесь.
 Посмотрите, как изменилась скорость соединения.  
Если она возросла, увеличьте ширину окна еще на один квик (не байт!),
если уменьшилась, – сузьте окно, а если осталась без изменений, – расширьте окно на пару квиков. Так, в конце концов, будет найдено оптимальное значение. Многие знатоки утверждают, что оптимальное значение ширины окна зависит от загруженности провайдера и сильно колеблется в течение суток.
Как снять ограничение TCP/IP соединений читайте  здесь  
Помимо вышеупомянутых опций реестр Windows содержит множество других значений, относящихся к TCP/IP, но обо всем рассказать в одной статье нереально.
Дальше будем эту тему тему расширять и обновлять.

          

Product Designer

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MI-Dearborn, Responsibilities: Maintain a user-centered approach in design perspective and practice Work as a collaborative team member with business partners, developers, and fellow designers Lead products from discovery and framework through iterative development and delivery Facilitate and lead design thinking sessions/workshops with various technical and non-technical stakeholders Help product managers ass
          

Pharmacy Technician | Vanderbilt Health

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Nashville, Tennessee, Description Day Shift - Pharmacy Technician Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating a
          

Pharmacy Technician - 100 Oaks Outpatient Pharmacy | Vanderbilt Health

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Nashville, Tennessee, Description Pharmacy Technician - 100 Oaks Outpatient Pharmacy Discovery Vanderbilt University Medical Center: Located in Nashville, T
          

Pharmacy Technician Trainee | Vanderbilt Health

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Nashville, Tennessee, Description Pharmacy Technician Trainee Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a
          

백트, 비트코인 선물 거래량 계속 경신…COO "BTC 성공하려면 실질적인 유용성 필요"

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세계 최대 거래소 그룹 인터컨티넨탈익스체인지(ICE) 산하 비트코인(Bitcoin, BTC) 선물 거래소 백트(Bakkt)의 수석운영책임(COO) 아담 화이트는 비트코인이 성공하려면 실제적인 유용성이 필요하다고 발언했다.

 

아담 화이트 수석은 26일(현지시간) EJ인사이트와의 인터뷰에서 백트가 시장 투기를 일으키지 않는 상품 구축을 위해 노력하고 있으며, 특히 ‘가격발견(price discovery)’과 리스크 헤징 관리에 있어 백트의 선물 계약이 긍정적으로 역할하고 있다고 강조했다.

 

또 이 같은 시장활용 사례 증가에도 비트코인이 '유용성(utility)'을 갖춰야 한다고 주장했다.

 

그는 "비트코인과 같은 디지털 자산이 실제적인 문제를 해결하는 데 사용돼야 한다. 이를 도입(adoption), 유용성(utility)라고 한다"며 "비트코인의 도입과 유용성을 강화하기 위해 별도의 부서를 두고 새로운 상품과 서비스를 개발하고 있다"고 설명했다.

 

수석은 스테이블 코인에 대해 아직 중립적인 입장이라 밝혔다. 그러면서도 "법정화폐를 담보하는 디지털 자산은 흥미로운 분야"라면서 "향후 위상이 더 높아지면 백트 커스터디 솔루션이 지원할 가능성도 고려한다"고 덧붙였다.

 

페이스북이 추진 중인 스테이블 코인 '리브라' 프로젝트에 대해서는 "규제 반발은 당연하다. 리브라는 전례 없이 경계를 확대해가고 있다"고 평가했다.

 

그는 "이러한 프로젝트가 생겨나고 추진되는 흐름 자체가 중요하다"면서 "문제가 있겠지만 현금 등 다른 것들은 할 수 없는 스테이블 코인만이 할 수 있는 부분이 있을 것"이라 전했다.

 

백트(Bakkt)는 암호화폐 선물 거래소로써 새로운 기관투자자를 유입시킬 것이란 큰 기대를 모았다. 지난 9월에는 실물 인도 비트코인 선물 상품을 출시했으며, 올해 안에 현물 인도 상품을 출시할 계획이다. 그 외 비트코인 옵션 상품도 준비 중이다.

 

비록 출발은 저조했지만 지난 몇 주 간 거래량과 미결제약정이 급증하며 각종 기록들을 연달아 경신하고 있다. 실제로 암호화폐 전문 분석업체 스큐(Skew)에 따르면 백트의 비트코인 선물 미결제약정(open interest) 규모는 100만 달러를 돌파했으며 거래량도 꾸준히 증가 중이다.

 

한편 백트 거래량 봇 트위터 계정 백트봇(@BakktBot)에 따르면, 미국 현지시간 기준 27일 백트 비트코인 선물 거래량이 5,6713 BTC로 역대 최고치를 경신했다. 

 

▲ 출처: 백트봇 트위터     © 코인리더스


이와 관련해 유명 암호화폐 전문 애널리스트 알렉스 크루거(Alex Krüger)는 트위터를 통해 "백트 비트코인 선물의 거래량이 대폭 증가하고 있다. 그러나 중점을 두어야할 점은 거래량이 아닌 실물인수도 규모다. 11월 BTC 선물 실물인수도 규모는 11 BTC, 10월은 15 BTC를 기록했다"고 말했다.

 

 

 


          

PARSHAS TOLDOS 5780

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STAM TORAH
PARSHAS TOLDOS 5780
“THE FIRE WITHIN”

            An Israeli journalist once asked a ba’al teshuva who he felt was greater, the little Yerushalmi children in Me’ah Shearim who have never had exposure to contemporary society, or he, who had reformed his entire life? The journalist assumed that the ba’al teshuva would reply that he is greater because he had left behind surroundings and familiarity of his youth in order to adopt a Torah lifestyle. However, the ba’al teshuva replied that in his opinion the Yerushalmi children are greater: “I experienced the trappings and pleasures of the outside world, and I am starkly aware that it’s ultimately empty and meaningless. To me, it’s clear that Torah provides true meaning and a life of direction and purpose. But those Yerushalmi children have no way of knowing that. To them the allure of the outside world still seems exciting and tempting. The fact that they maintain their beliefs anyway requires faith and dedication that are beyond me.”   

          The prophet Yeshaya conveyed to the nation that G-d was displeased with their Service to Him: “G-d said: Since this people has drawn close, with its mouth and with its lips it has honored Me, yet it has distanced its heart from me; their fear of me is כמצות אנשים מלומדה - like rote of human commands.”[1]
          One of the greatest challenges we face is to maintain a level of excitement and passion when doing mitzvos and serving Hashem, particularly regarding those mitzvos we perform on a daily basis. When a young man dons his tefillin for the first time shortly prior to his bar mitzvah, he is extremely excited and proud. But with time that excitement wanes and becomes a matter of rote, especially during those mornings when he is tired. 
          When Yitzchak and Rivka davened for a child the Torah states, “And Hashem heeded hiscries, and his wife Rivka conceived.”[2] Rashi explains that Hashem listened to the prayers of Yitzchak more than to the prayers of Rivka, because the prayers of a righteous person who is the child of a wicked person[3], cannot compare to the prayers of a righteous person who is the child of a righteous person[4].
          The words of Rashi are surprising. One would think that one born and raised among heretics who pulled himself up by the bootstraps to become a devout believer is greater than one born into a reputable upstanding home. In addition, the gemara[5]states, “In the place where one who has repented stands, the most perfectly righteous cannot stand.” If so, why was Rivka’s prayers not as poignant, if not more poignant, than those of Yitzchak?
          Rabbi Sholom Schwadron zt’l related that one day a man was standing next to the marketplace minding his own business watching people busily shopping. Suddenly, he felt two hard jabs at his chest. As he looked up angrily to see who had punched him, he realized that he was in the middle of saying Shemone Esrei and had just recited the beracha, Selach Lanu.[6]
          Rabbi Simcha Wasserman zt’l explained that a person who decides to revolutionize his life by adopting a Torah lifestyle that was completely unfamiliar to him, reaches spiritual levels that even surpasses the most righteous individuals, who did not have to undergo such struggle to achieve that connection. Still, one who repents generally does so because he felt internal strife and emptiness. He was searching and yearning for meaning and knew that something had to change in his life. It was that journey and self-discovery that led him to a path of Torah and mitzvah observance.
          One born into a home of Torah values however, never knew of anything different. For that person, it is a greater challenge to appreciate the privilege he was been born into, as a Torah observant Jew. One who has been davening three times a day, repeating the same words all his life, inevitably has a more difficult time finding meaning in his prayers. That is why the sincere prayers of one born into a home of righteousness, are greater than the prayers of one raised in a home that does not practice Torah values. One who developed an appreciation for prayer looks forward to the thrice daily opportunity for connection, and therefore it is not as great of a challenge for him to daven. One who was trained in it from youth, can maintain his callow understanding of prayer throughout his life, and never develop that appreciation for the greatness and opportunity of prayer. For him to do so, requires overcoming habit and rote, which is always a formidable challenge.[7]   

          In the daily Shema we recite: “And these matters that I command you today shall be upon your heart.”[8]The Medrash comments that each day a person should feel as if that day G-d commanded him to perform the mitzvos.[9]
          Shema is the mantra of every Jew. The custom is to recite Shema in the presence of an infant boy the night before his b’ris milah. Just before a person leaves this world, if he has the ability, he recites Shema. Twice a day, every day, morning and evening, a Jew recites Shema, and then repeats it again just before he retires for the night. 
          It is therefore particularly in the Shema recitation that we are commanded to maintain a sense of freshness and excitement for Avodas Hashem. We should never take for granted the message of Shema. Just as the world does not run on automatic pilot, but is renewed by G-d each day, so must our Service to Him be performed with renewed vigor and excitement each day.
         
          In days of old, a watchman was stationed at all railroad crossings. He would sit at the top of a tower next to the crossing. If he would see a horse and buggy traveling toward the crossing as a train was speeding down the track, he would wave a flaming torch in all directions to warn the conductor.
          One cloudy day, the watchman saw an oncoming train rapidly approaching the crossing just as a horse and wagon slowly made its way across the tracks. The watchman grabbed his wooden stick, raced to the top of the tower, and began waving it in all directions. But no matter how vigorously he waved the stick the train would not slow down. Moments later, the train crashed into the horse and buggy causing significant devastation and loss of life.
          The watchman was forced to stand trial in court with serious allegations leveled against him, which included involuntary manslaughter. When the charges were announced the watchman was indignant. “I did my job. I waved that torch as hard as I could. It was the conductor who should be charged for not adhering to the warning!” The prosecution sharply replied, “It doesn’t matter how much you waved the stick. You neglected to fulfill your primary duty, which is to light the stick before you start waving it. If there is no fire atop the stick, the conductor won’t see it, so how can he understand its message?!”
          Prayer is incredibly powerful, and its words are incredibly poignant. But words recited without emotion cannot compare with those recited passionately. The concentration and fervor we have while praying is the fire that propels those words to far greater heights.[10]
          The Sages explain that “G-d desires heart”[11]. It’s not merely about what we do, but also how we do it. That is true all of our actions, especially prayer.
          The prophet Yechezkel informed the nation:  “I will give you a new heart and put a new spirit within you; I will remove the heart of stone from your flesh and give you a heart of flesh.”[12]Our task is to seek that sense of freshness and excitement in the mundane and not allow what we do to become a matter of rote.
          The sad truth of life is that we often don’t appreciate our greatest gifts. But it doesn’t have to be that way. With a little bit of reflection, we can elevate every day and savor the blessings we are granted.

          “Hashem heeded his cries”
          “These matters that I command you today shall be upon your heart.”

Rabbi Dani Staum LMSW
Rebbe, Heichal HaTorah, Teaneck, NJ
Principal, Ohr Naftali, New Windsor NY



[1] Yeshaya 29:13
[2]Bereishis 25:22
[3] The righteous Rivka was the daughter of the wicked Besuel
[4] The righteous Yitzchok was the son of the righteous Avrohom
[5]Berachos 34a
[6] The custom is that we strike our chests twice when reciting that beracha. Rabbi Schwadron was humorously depicting how we often pray as if on autopilot, allowing our mouths to recite the familiar words out of habit, while our minds are completely elsewhere.  
[7]It is truly inspiring to watch the manner in which ba’alei teshuva daven with intense concentration.
[8] Devorim 6:6
[9] Sifrei, Devorim 31
[10]Rabbi Aharon Lopianski notes that it is not always as important to understand the meaning of every single word as it to understand the general gist of what one is saying. When one has a general understanding of the words it is far easier to relate to them and to maintain concentration.
[11]  זוהר, רעיא מהימנא ג', כי תצא רפא, סנהדרין קו:
[12]Yecheskel 32:26


          

2019 Mercedes Benz GLC Facelift India Launch on December 3

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2019 Mercedes Benz GLC Facelift, unveiled at the Geneva Motor Show in March, will rival the likes of BMW X3, Audi Q5, Volvo XC60, and Land Rover Discovery Sport.
          

Findmypast Announces Dundee & Angus Collection Partnership

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I received this information from Findmypast today:

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FINDMYPAST ANNOUNCES DUNDEE & ANGUS COLLECTION PARTNERSHIP
OVER 6 MILLION RECORDS RELEASED ON FINDMYPAST, MANY FOR THE FIRST TIME ONLINE
        Findmypast publish largest online collection of Dundee historical records
        Multiple archives come together to give a comprehensive picture of life in one of Scotland’s most notable areas, searchable by name  for the first time
        Includes original photographs of individuals and long forgotten scenes of the past, birth, marriages and deaths, tax records, electoral registers and more
        Release builds on Findmypast’s rapidly expanding collection of Scottish records, now one of the largest available online
Dundee, Scotland - November 29th 2019
Leading British and Irish family history website, Findmypast, is proud to announce a new online collection spanning nearly five centuries of Dundee and Angus history. Published in association with Leisure and Culture Dundee, University of St Andrews Library and DC Thomson, this vast archive of historical documents and original photographs provides researchers worldwide with the opportunity to discover their connections to the City of Discovery in unprecedented detail, for the first time online.
Dundee based Findmypast has scanned in full colour from paper originals where possible, and created a full name index.  This new release brings together millions of complementary records from multiple institutions, which, when placed alongside existing Findmypast Scottish collections, forms one of the most comprehensive collections of genealogical records from any area of the UK online.
These records give names, dates, residences, occupations and document life events of the people of Dundee and Angus, also including photographic records of streets and people, a goldmine for social and family historians alike. They contain some of the oldest photographs in existence, taken in the 1840s and showing parts of the city long since lost to redevelopment.
A particular highlight is a set of 50 images of ‘Dundee Old & New’ commissioned by the Dundee Police after the Improvement Act of 1871. This photographic album illustrates the changing landscape of a Victorian burgh in the firm grip of the Industrial Revolution through a unique ‘then and now’ perspective even at that time. When used alongside tenancy and electoral records of the people who lived in these streets released at the same time and going back to as early as 1823, a detailed picture of the people of Dundee can be seen, rich and fertile ground for tracing ancestors who stood on those cobblestones.
These exciting new records include:
       Fully indexed images of more than 23,600 Obituaries from local Dundee newspapers ranging from 1869-2018, added to a national Scottish collection of over 600,000.
       2 million Valuation Rolls 1823-1938 for the county of Dundee & Angus
       Hundreds of thousands of indexed records of baptismmarriage & burial from across Dundee & Angus 1562-1855.
       Portrait photographs of 318 male and female employees of DC Thomson who enlisted during the Second World War.
       Over 5,000 comprehensively indexed original photographs of Dundee & Angus dating 1844-2010.
Myko Clelland, Scottish Licensing Manager at Findmypast said ‘As a company with strong local roots, we’re thrilled to be working with partners to create one of the most comprehensive record collections for any area in the UK. We’re bringing so many different records together to give a detailed picture of the changing face of Dundee and Angus through its most transformative centuries, for the first time online. This is a unique chance to discover for ourselves the role that our ancestors played in history, allowing those connected to the area to uncover new stories, wherever they are in the world.’
Dr Erin Farley, Library & Information Officer at Leisure and Culture Dundee said ‘The Local History Centre at Dundee Libraries has been committed to helping people from Dundee and further afield discover their family histories for decades, and we are excited to offer library members access to this brilliant range of records, and new ways to search genealogical collections. We’re looking forward to hearing the stories that our members discover about their families, and finding out how our collections connect to others in Dundee and Angus.’
Rachel Nordstrom, Photographic Collections Manager of the University of St Andrews Library said ‘As the Home of Scottish Photography St Andrews played host to many great photographers over the past 180 years, and the University archives does indeed hold a great number of photographic images from across Scotland which we could draw from for this exciting and engaging initiative. We’re delighted to bring our collections to a new audience and give them new life through Findmypast for their local, national and international family heritage researchers. The images shared through this project are from some of the most notable photographers of the 19th century, and their portrayal of local life, landscape and architecture complements these newly published records while giving a view of what life was like for our forebears.’
David Powell, Archive Manager at DC Thomson said ‘DC Thomson share our Dundee Headquarters with Findmypast and we're excited that holdings from our own corporate archives can contribute to such a comprehensive online collection. It's fitting that the names and faces of those who walked through these same Meadowside doors are now having part of their own stories told online for researchers to link with other available records to broaden their knowledge.’
By improving access to these rich documents and making them searchable for the first time, Findmypast provides family historians from around the world with even more opportunities to discover their Dundee & Angus ancestors. Researchers can now uncover details of their families past and add new generations to their family tree with greater ease than ever before.
With today’s release building on existing records from The National Archives, Scottish Catholic Archives, British Library, Tay Valley Family History Society, and more from the area, together with the publication of almost 10 million records from Scotland since January, (many exclusive and nowhere else online), Findmypast is cementing their reputation as the home of British & Irish family history, creating one of the most useful genealogical resources online for Scottish research.
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Disclosure:  I have a complimentary subscription to Findmypast, and have accepted meals and services from Findmypast, as a Findmypast Ambassador.  This has not affected my objectivity relative to Findmypast and its products.

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Copyright (c) 2019, Randall J. Seaver

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Scenic Eclipse Crew Profile:

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LATTE was recently a guest aboard Scenic Luxury Cruises & Tours’ Discovery Yacht, Scenic Eclipse, where we sailed the Caribbean Sea visiting ports in Jamaica, Guatemala, Honduras, Belize and Mexico. We took the opportunity to speak with a number of crew and personnel while on board to learn more about their cruise industry background, their reason for joining Scenic Eclipse in its inaugural season, and some of their favourite ports and parts of the World’s First Discovery Yacht.

The post Scenic Eclipse Crew Profile: appeared first on LATTE Luxury News.


          

Scenic Eclipse Crew Profile: Strawberry Mae Besin

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LATTE was recently a guest aboard Scenic Luxury Cruises & Tours’ Discovery Yacht, Scenic Eclipse, where we sailed the Caribbean Sea visiting ports in Jamaica, Guatemala, Honduras, Belize and Mexico.

The post Scenic Eclipse Crew Profile: Strawberry Mae Besin appeared first on LATTE Luxury News.


          

Discovery Geometric Single Light Large Ceiling Pendant

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Discovery Geometric Single Light Large Ceiling Pendant

Discovery Geometric Single Light Large Ceiling Pendant

Discovery CG0642 Geometric Discovery Geometric single light large ceiling pendant in an antique brass finish. This abstract ceiling pendant with an angular design displays an abundance of geometric shapes which form the open frame of the pendant. A classic touch is added with the antique brass finish. Height adjustable at the point of installation. This product code is CG0642. Smaller versions are available to match.


          

Discovery Geometric Single Light Medium Sized Ceiling Pendant

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Discovery Geometric Single Light Medium Sized Ceiling Pendant

Discovery Geometric Single Light Medium Sized Ceiling Pendant

Discovery CG0641 Geometric Discovery Geometric single light medium ceiling pendant in an antique brass finish. This abstract ceiling pendant with an angular design displays an abundance of geometric shapes which form the open frame of the pendant. A classic touch is added with the antique brass finish. Height adjustable at the point of installation. This product code is CG0641. A smaller and a larger size are available to match.


          

Discovery Geometric Single Light Ceiling Pendant in Antique Brass Finish

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Discovery Geometric Single Light Ceiling Pendant in Antique Brass Finish

Discovery Geometric Single Light Ceiling Pendant in Antique Brass Finish

Discovery CG0640 Geometric Discovery Geometric single light ceiling pendant in an antique brass finish. This abstract ceiling pendant with an angular design displays an abundance of geometric shapes which form the open frame of the pendant. A classic touch is added with the antique brass finish. Height adjustable at the point of installation. This product code is CG0640. Larger sizes are available to match.


          

Elstead Lighting Bronx Single Light Tiffany Style Table Lamp

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Elstead Lighting Bronx Single Light Tiffany Style Table Lamp

Elstead Lighting Bronx Single Light Tiffany Style Table Lamp

Discovery CG0655 Bronx Discovery Bronx single light Tiffany style table lamp with crystal detail. Timelessly styled with neutral colours, this Tiffany style table lamp exudes elegance. The domed shades has tones of brown and cream throughout, whilst the lower edges of the pattern are inset with crystal detail, providing an unexpected sparkle. The curvaceous base has a classic antique brass finish. This product code is CG0655.      


          

Discovery Aviary Single Light Globe Pendant in Polished Nickel Finish

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Discovery Aviary Single Light Globe Pendant in Polished Nickel Finish

Discovery Aviary Single Light Globe Pendant in Polished Nickel Finish

Discovery CG0372 Aviary Discovery Aviary single light ceiling pendant in polished nickel finish. The globe shaped shade of this ceiling pendant makes it a noticeable addition for any suitable room. The modern polished chrome frame of the shade swirls and criss crosses resembling the beauty of a traditional aviary.  Height adjustable at the point of installation. This product code is CG0372.


          

Discovery Aviary Single Light Ceiling Pendant in Polished Nickel Finish

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Discovery Aviary Single Light Ceiling Pendant in Polished Nickel Finish

Discovery Aviary Single Light Ceiling Pendant in Polished Nickel Finish

Discovery CG0371 Aviary Discovery Aviary single light ceiling pendant in polished nickel finish. The elongated shape of the shade makes this ceiling pendant a noticeable addition for any suitable room. The modern polished chrome frame of the shade swirls and criss crosses resembling the beauty of a traditional aviary.  Height adjustable at the point of installation. This product code is CG0371.


          

Discovery Aviary Single Light Oval Ceiling Pendant in Polished Nickel Finish

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Discovery Aviary Single Light Oval Ceiling Pendant in Polished Nickel Finish

Discovery Aviary Single Light Oval Ceiling Pendant in Polished Nickel Finish

Discovery CG0370 Aviary Discovery Aviary single light ceiling pendant in polished nickel finish. The oval shaped shade of this ceiling pendant makes it a noticeable addition for any suitable room. The modern polished chrome frame of the shade swirls and criss crosses resembling the beauty of a traditional aviary.  Height adjustable at the point of installation. This product code is CG0370.  


          

Discovery Endeavour 3 Light Ceiling Pendant in Polished Nickel Finish

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Discovery Endeavour 3 Light Ceiling Pendant in Polished Nickel Finish

Discovery Endeavour 3 Light Ceiling Pendant in Polished Nickel Finish

Discovery CG0433 Endeavour  Discovery Endeavour 3 light ceiling pendant in polished nickel finish. A fabulous addition for any home, this polished nickel ceiling pendant is designed with history in mind. The nautical influences are apparent with tension detailing at the top of the central domed shade. A frosted glass diffuser softens the light creating an even illumination. Height adjustable at the point of installation.  This product code is CG0433. A single light version is also available to match.


          

Discovery Endeavour Single Light Ceiling Pendant in Polished Nickel Finish

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Discovery Endeavour Single Light Ceiling Pendant in Polished Nickel Finish

Discovery Endeavour Single Light Ceiling Pendant in Polished Nickel Finish

Discovery CG0431 Endeavour  Discovery Endeavour single light ceiling pendant in polished nickel finish. A fabulous addition for any home, this polished nickel ceiling pendant is designed with history in mind. The nautical influences are apparent with tension detailing at the top of the domed shade. A frosted glass diffuser softens the light creating an even illumination. Height adjustable at the point of installation.  This product code is CG0431. A 3 light version is also available to match.


          

Discovery Astronomer 2 Light Wall Fitting in Polished Chrome Finish

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Discovery Astronomer 2 Light Wall Fitting in Polished Chrome Finish

Discovery Astronomer 2 Light Wall Fitting in Polished Chrome Finish

Discovery CG0553 Astronomer Discovery Astronomer 2 light wall fitting in polished chrome finish with smoked glass globe shades. This spectacular wall fitting displays a striking ensemble of smoked glass globe shades attached to a linear polished chrome frame. The random arrangement of the globes invites curiosity whilst making its mark as a stunning additon for any suitable room. This product code is CG0553. Matching lamps and a ceiling light are available in the Astronomer collection.


          

Discovery Astronomer 3 Light Table Lamp in Polished Chrome Finish

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Discovery Astronomer 3 Light Table Lamp in Polished Chrome Finish

Discovery Astronomer 3 Light Table Lamp in Polished Chrome Finish

Discovery CG0552 Astronomer Discovery Astronomer 3 light table lamp in polished chrome finish with smoked glass globe shades. This spectacular table lamp displays a striking ensemble of smoked glass globe shades attached to a linear polished chrome stem. The random arrangement of the globes invites curiosity whilst making its mark as a stunning addition for any suitable room. Operated by an in-line rocker switch. This product code is CG0552. Matching floor lamp, ceiling fitting and a wall light are available in the Astronomer collection.


          

Discovery Astronomer 8 Light Floor Lamp with Polished Chrome Finish

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Discovery Astronomer 8 Light Floor Lamp with Polished Chrome Finish

Discovery Astronomer 8 Light Floor Lamp with Polished Chrome Finish

Discovery CG0551 Astronomer Discovery Astronomer 8 light floor lamp in polished chrome finish with smoked glass globe shades. This spectacular floor lamp displays a striking ensemble of smoked glass globe shades attached to a linear polished chrome stem. The random arrangement of the globes invites curiosity whilst making its mark as a stunning addition for any suitable room. Operated by a foot switch. This product code is CG0551. Matching table lamp, ceiling fitting and a wall light are available in the Astronomer collection.


          

Discovery Astronomer 7 Light Ceiling Pendant in Polished Chrome Finish

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Discovery Astronomer 7 Light Ceiling Pendant in Polished Chrome Finish

Discovery Astronomer 7 Light Ceiling Pendant in Polished Chrome Finish

Discovery CG0550 Astronomer Discovery Astronomer 7 light ceiling pendant in polished chrome finish with smoked glass globe shades. This spectacular ceiling light fitting displays a striking ensemble of smoked glass globe shades attached to a linear polished chrome frame. The random arrangement of the globes invites curiosity whilst making its mark as a stunning centre piece for any suitable room. Height adjustable at the point of installation. This product code is CG0550. Matching lamps and a wall light are available in the Astronomer collection.


          

Discovery Sketch Single Light Ceiling Pendant in Antique Chrome Finish

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Discovery Sketch Single Light Ceiling Pendant in Antique Chrome Finish

Discovery Sketch Single Light Ceiling Pendant in Antique Chrome Finish

Discovery CG0620 Sketch Discovery Sketch single light ceiling pendant with antique copper finish. This modernistic ceiling pendant is striking in it's design. The geometric shapes of the cage shade add interest and a sense of curiosity to this ceiling light, whilst the antique copper finish provides a sense of individuality from the usual ceiling light colours. Height adjustable at the point of installation. This product code is CG0620. A larger version is available to match.


          

Discovery Sketch Single Light Large Ceiling Pendant in Antique Copper Finish

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Discovery Sketch Single Light Large Ceiling Pendant in Antique Copper Finish

Discovery Sketch Single Light Large Ceiling Pendant in Antique Copper Finish

Discovery CG0621 Sketch Discovery Sketch single light large ceiling pendant with antique copper finish. This modernistic ceiling pendant is striking in it's design. The geometric shapes of the cage shade add interest and a sense of curiosity to this ceiling light, whilst the antique copper finish provides a sense of individuality from the usual ceiling light colours. Height adjustable at the point of installation. This product code is CG0621. A smaller version is available to match.


          

Discovery Dresden Single Light Tiffany Style Table Lamp with Grey Detail

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Discovery Dresden Single Light Tiffany Style Table Lamp with Grey Detail

Discovery Dresden Single Light Tiffany Style Table Lamp with Grey Detail

Discovery CG5011 Dresden Discovery Dresden single light tiffany style table lamp with grey colouring and crystal detail. This charming Tiffany style table lamp is an ideal addition for any home. The neutral main colour is accented by the grey rim and inset with crystal detail adding an unexpected sparkle to this adorable lamp. This product code is CG5011 Also available in other colour tones.


          

Discovery Dresden Single Light Tiffany Style Table Lamp with Blue Detail

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Discovery Dresden Single Light Tiffany Style Table Lamp with Blue Detail

Discovery Dresden Single Light Tiffany Style Table Lamp with Blue Detail

Discovery CG5010 Dresden Discovery Dresden single light tiffany style table lamp with blue and cream colouring and crystal detail. This charming Tiffany style table lamp is an ideal addition for any home. The neutral main colour is accented by the blue rim and inset with crystal detail adding an unexpected sparkle to this adorable lamp. This product code is CG5010 Also available in other colour tones.


          

Discovery Bobbin Single Light Ceiling Pendant in Matt Black Finish

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Discovery Bobbin Single Light Ceiling Pendant in Matt Black Finish

Discovery Bobbin Single Light Ceiling Pendant in Matt Black Finish

Discovery CG0543 Bobbin Discovery Bobbin single light ceiling pendant in a matt black finish. This modern ceiling pendant has a cylindrical shaped shade, with a stylish matt black frame and a clear glass surround which allows maximum light output. Ideal for either a modern or more traditional property.  Height adjustable at the point of installation. This product code is CG0543. Also available in a polished chrome finish.


          

Discovery Bobbin 2 Light Ceiling Pendant in Matt Black Finish

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Discovery Bobbin 2 Light Ceiling Pendant in Matt Black Finish

Discovery Bobbin 2 Light Ceiling Pendant in Matt Black Finish

Discovery CG0541 Bobbin Discovery Bobbin 2 light ceiling pendant in a matt black finish. This modern ceiling pendant has a drum shaped shade, with a stylish matt black frame and a clear glass surround, which allows maximum light output. Ideal for either a modern or more traditional property.  Height adjustable at the point of installation. This product code is CG0541. Also available in a polished chrome finish.


          

Discovery Bobbin Single Light Ceiling Pendant in Polished Chrome Finish

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Discovery Bobbin Single Light Ceiling Pendant in Polished Chrome Finish

Discovery Bobbin Single Light Ceiling Pendant in Polished Chrome Finish

Discovery CG0542 Bobbin Discovery Bobbin single light ceiling pendant in polished chrome finish. This modern ceiling pendant has a cylindrical shaped shade, with a polished chrome frame and a clear glass surround which allows maximum light output. Ideal for either a modern or more traditional property.  Height adjustable at the point of installation. This product code is CG0542. Also available in matt black finish.


          

Discovery Bobbin 2 Light Ceiling Pendant in Polished Chrome Finish

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Discovery Bobbin 2 Light Ceiling Pendant in Polished Chrome Finish

Discovery Bobbin 2 Light Ceiling Pendant in Polished Chrome Finish

Discovery CG0540 Bobbin Discovery Bobbin 2 light ceiling pendant in polished chrome finish. This modern ceiling pendant has a drum shaped shade, with a polished chrome frame and a clear glass surround which allows maximum light output. Ideal for either a modern or more traditional property.  Height adjustable at the point of installation. This product code is CG0540. Also available in matt black finish.


          

Discovery Endeavour 3 Light Ceiling Fitting in Antique Brass Finish

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Discovery Endeavour 3 Light Ceiling Fitting in Antique Brass Finish

Discovery Endeavour 3 Light Ceiling Fitting in Antique Brass Finish

Discovery CG0432 Endeavour  Discovery Endeavour 3 light ceiling pendant in antique brass finish. A fabulous addition for any home, this antique brass ceiling pendant is designed with history in mind. The nautical influences are apparent with tension detailing at the top of the central domed shade. A frosted glass diffuser softens the light creating an even illumination. Height adjustable at the point of installation.  This product code is CG0432. A single light version is also available to match.


          

Discovery Dresden Single Light Tiffany Style Table Lamp with Red Detail

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Discovery Dresden Single Light Tiffany Style Table Lamp with Red Detail

Discovery Dresden Single Light Tiffany Style Table Lamp with Red Detail

Discovery CG5009 Dresden Discovery Dresden single light tiffany style table lamp with red and cream colouring and crystal detail. This charming Tiffany style table lamp is an ideal addition for any home. The neutral main colour is accented by the red rim and inset with crystal detail adding an unexpected sparkle to this adorable lamp. This product code is CG5009 Also available in other colour tones.


          

Discovery Dresden Single Light Tiffany Style Table Lamp with Brown Detail

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Discovery Dresden Single Light Tiffany Style Table Lamp with Brown Detail

Discovery Dresden Single Light Tiffany Style Table Lamp with Brown Detail

Discovery CG5008 Dresden Discovery Dresden single light tiffany style table lamp with brown and cream colouring and crystal detail. This charming Tiffany style table lamp is an ideal addition for any home. The neutral main colour is accented by the brown rim and inset with crystal detail adding an unexpected sparkle to this adorable lamp. This product code is CG5008 Also available in other colour tones.


          

Discovery Dresden Single Light Tiffany Style Table Lamp with Green Detail

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Discovery Dresden Single Light Tiffany Style Table Lamp with Green Detail

Discovery Dresden Single Light Tiffany Style Table Lamp with Green Detail

Discovery CG5007 Dresden Discovery Dresden single light tiffany style table lamp with green and cream colouring and crystal detail. This charming Tiffany style table lamp is an ideal addition for any home. The neutral main colour is accented by the green rim and inset with crystal detail adding an unexpected sparkle to this adorable lamp. This product code is CG5007 Also available in other colour tones.


          

Arkfeld on electronic discovery and evidence

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Find this book at the following location at the Wisconsin State Law Library, Dane County Legal Resource Center, or Milwaukee County Legal Resource Center: Treatise
          

Arkfeld's best practices guide for electronic discovery and evidence

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Find this book at the following location at the Wisconsin State Law Library, Dane County Legal Resource Center, or Milwaukee County Legal Resource Center: Treatise
          

Pretrial discovery: strategy and tactics

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Find this book at the following location at the Wisconsin State Law Library, Dane County Legal Resource Center, or Milwaukee County Legal Resource Center: Treatise
          

Wisconsin discovery law and practice

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Find this book at the following location at the Wisconsin State Law Library, Dane County Legal Resource Center, or Milwaukee County Legal Resource Center: Reference, Treatise, MCLL, DCLL
          

Cannot install DIGI ME firmware on DIGI ME4

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We have used Digi Me DC-ME-01T for many years (this is 2 Mb flash part). Recently they said our part will be replaced by Digi Me4 and gave us some samples. However, when using same Digi Discovery tool to install firmware we get following message: Unable to update firmware. Image does not support this hardware.
I downloaded latest Digi Discovery tool but it made no difference.
Thanks in advance for your help.
Felix
Spellman High Voltage
          

A Brief Look at Crime 11/18 – 11/24

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Judge sets $5,000 bail for woman police say killed husband over illegal gambling The woman police say stabbed her husband in Quincy following the discovery of an illegal basement gambling operation is being held on $5,000 cash bail. Huixian Liu was arraigned in Norfolk Superior Court Thursday after a grand jury indicted her for manslaughter […]
          

Co2 - Virage sur l'aile pour Land Rover

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En attendant une gamme 100 % électrifiée programmée pour 2022, Land Rover propose son Discovery Sport équipé de la micro-hybridation. Pour réduire - un peu - ses émissions de CO2.
          

Workshop details announced for SMi's AI in Drug Discovery Conference 2020

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SMi Reports: Robert Young from Blue Burgundy to lead AI in Drug Discovery 2020 workshop in March 2020.
          

OPENNMS-OPENNMS-165 has FAILED : Updated by Bamboo Administrator

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Changes by Bamboo Administrator

OPENNMS-OPENNMS-165 has the following 10 changes:

Jesse White made the following changes at 27 Nov 2019, 11:16:14 AM
with the comment: NMS-12412: Fix a number of problems with Drools in alarmd
* Fix flapping between clear & unclear rules
* Limit # of queued actions - help prevent OOM
* Only add alarm facts to the Drools session once the related transacation has been succesfully flushed
  * This fixes flapping tests and intermittent errors related to inconsistent database states
* Fix exception handling in fire thread

  • core/test-api/alarms/src/main/java/org/opennms/core/test/alarms/driver/AlarmdDriver.java
  • core/test-api/alarms/src/main/java/org/opennms/core/test/alarms/driver/Scenario.java
  • opennms-alarms/daemon/pom.xml
  • opennms-alarms/daemon/src/main/java/org/opennms/netmgt/alarmd/AlarmLifecycleListenerManager.java
  • opennms-alarms/daemon/src/main/java/org/opennms/netmgt/alarmd/AlarmPersisterImpl.java
  • opennms-alarms/daemon/src/main/java/org/opennms/netmgt/alarmd/drools/AlarmService.java
  • opennms-alarms/daemon/src/main/java/org/opennms/netmgt/alarmd/drools/DefaultAlarmService.java
  • opennms-alarms/daemon/src/main/java/org/opennms/netmgt/alarmd/drools/DroolsAlarmContext.java
  • opennms-alarms/daemon/src/main/java/org/opennms/netmgt/alarmd/drools/ManagedDroolsContext.java
  • opennms-alarms/daemon/src/test/java/org/opennms/netmgt/alarmd/AlarmLifecycleListenerManagerIT.java
  • opennms-alarms/daemon/src/test/java/org/opennms/netmgt/alarmd/AlarmLifecycleListenerManagerSnapshotTest.java
  • opennms-alarms/daemon/src/test/java/org/opennms/netmgt/alarmd/AlarmdIT.java
  • opennms-alarms/daemon/src/test/java/org/opennms/netmgt/alarmd/drools/DroolsAlarmContextIT.java
  • opennms-alarms/integration-tests/src/test/java/org/opennms/netmgt/alarmd/itests/AlarmdBlackboxIT.java
  • opennms-base-assembly/src/main/filtered/etc/alarmd/drools-rules.d/alarmd.drl
  • opennms-base-assembly/src/main/filtered/etc/jmx-datacollection-config.xml
  • opennms-model/src/main/java/org/opennms/netmgt/model/OnmsAlarm.java

Chandra Gorantla made the following changes at 26 Nov 2019, 8:35:45 AM
with the comment: NMS-12385: Handle exclude-range in Discovery definitions (#2807)
* NMS-12385: Add location to exclude range and fix exclude-range handling in definitions

exclude-range now supports specifying location.
If exclude-range is in definitions it inherits location from definition.

* NMS-12385: Handle review comments

* NMS-12385: Handle review comments

  • core/lib/src/main/java/org/opennms/core/utils/LocationUtils.java
  • opennms-config-api/src/main/java/org/opennms/netmgt/config/api/DiscoveryConfigurationFactory.java
  • opennms-config-model/src/main/java/org/opennms/netmgt/config/discovery/ExcludeRange.java
  • opennms-config-model/src/main/resources/xsds/discovery-configuration.xsd
  • opennms-config/src/main/java/org/opennms/netmgt/config/DiscoveryConfigFactory.java
  • opennms-config/src/test/java/org/opennms/netmgt/config/DiscoveryConfigFactoryTest.java
  • opennms-provision/opennms-provision-persistence/src/test/java/org/opennms/netmgt/provision/persist/MockDiscoveryConfigurationFactory.java
  • opennms-webapp/src/main/java/org/opennms/web/admin/discovery/ActionDiscoveryServlet.java
  • opennms-webapp/src/main/java/org/opennms/web/admin/discovery/DiscoveryScanServlet.java
  • opennms-webapp/src/main/webapp/admin/discovery/add-er.jsp
  • opennms-webapp/src/main/webapp/admin/discovery/edit-config.jsp
  • opennms-webapp/src/main/webapp/admin/discovery/edit-scan.jsp

Jesse White made the following changes at 25 Nov 2019, 4:20:00 PM
with the comment: Saturday Night's Alright

  • .circleci/config.yml

Bamboo Administrator made the following changes at 26 Nov 2019, 11:17:47 PM
with the comment: [bamboo] Automated branch merge (from foundation-2019:6459da6557fe5d5576faff013858dd3180cf4784)

Jesse White made the following changes at 22 Nov 2019, 12:23:09 PM
with the comment: Perform code coverage weekly instead of nightly.

  • .circleci/config.yml

Bamboo Administrator made the following changes at 28 Nov 2019, 11:36:12 PM
with the comment: [bamboo] Automated branch merge (from foundation-2019:2c71eac0f35d79741f638dcc1da0a220663880b9)

Jesse White made the following changes at 26 Nov 2019, 8:53:51 PM
with the comment: Merge pull request #2822 from OpenNMS/jw/weekly-coverage
Perform code coverage weekly instead of nightly

Bamboo Administrator made the following changes at 29 Nov 2019, 4:35:54 PM
with the comment: [bamboo] Automated branch merge (from release-25.1.1:7187fae380dd35e9d3e990f8ddec52ee0febb542)

Chandra Gorantla made the following changes at 27 Nov 2019, 2:16:48 PM
with the comment: NMS-12396: Handle SNMP profiles by default in NodeScan (#2824)
* NMS-12399: Add more exception checks for snmp errors

* NMS-12396: NodeScan should process snmp profiles by default

Even when SNMP service is not detected, try to get agent config
from profiles in order to scan the node for SNMP interfaces.

* NMS-12396: Add test for scanning node without SNMP service

  • opennms-provision/opennms-provisiond/pom.xml
  • opennms-provision/opennms-provisiond/src/main/java/org/opennms/netmgt/provision/service/DefaultProvisionService.java
  • opennms-provision/opennms-provisiond/src/main/java/org/opennms/netmgt/provision/service/NodeInfoScan.java
  • opennms-provision/opennms-provisiond/src/main/java/org/opennms/netmgt/provision/service/NodeScan.java
  • opennms-provision/opennms-provisiond/src/main/java/org/opennms/netmgt/provision/service/ProvisionService.java
  • opennms-provision/opennms-provisiond/src/test/java/org/opennms/netmgt/provision/service/NodeInfoScanIT.java
  • opennms-provision/opennms-provisiond/src/test/java/org/opennms/netmgt/provision/service/NodeScanIT.java
  • opennms-provision/opennms-provisiond/src/test/java/org/opennms/netmgt/provision/service/ProvisionerIT.java
  • opennms-provision/opennms-provisiond/src/test/java/org/opennms/netmgt/provision/service/ProvisionerTest.java
  • opennms-provision/opennms-provisiond/src/test/java/org/opennms/netmgt/provision/service/SnmpExceptionValidatorTest.java
  • opennms-provision/opennms-provisiond/src/test/resources/requisition_snmp_primary_but_no_service.xml
  • opennms-provision/opennms-provisiond/src/test/resources/testScanWithoutSnmpService.xml

Jesse White made the following changes at 28 Nov 2019, 9:54:25 AM
with the comment: Merge pull request #2831 from OpenNMS/jw/more-alarms
NMS-12412: Fix a number of problems with Drools in alarmd

The build has 0 failed tests and 7974 successful tests.


          

Jet Connections: ELO Related Albums 1979-80

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#1,497: With the back to back success of "Out Of The Blue" (1978), "Discovery" (1979) and "Xanadu" (1980) under their belts, Jeff Lynne and the Electric Light Orchestra (ELO) were at their commercial peak as the seventies lapsed into the eighties both in terms of record and ticket sales. Everything they released charted whether it was a single, a new album, a compilation or even a boxed set. This was, of course, good news for both the band and their label since 1975: Don Arden's Jet Records.

ELO were still regarded as a septet by many fans at this time, even though their studio recordings began to revolve around Jeff Lynne, Bev Bevan, Richard Tandy and Kelly Groucutt. It was during this time that various members of ELO's string section began to release albums via Jet (when distributed by CBS) in their own right and/or with side projects. Four albums were issued in total (and a number of singles too, the subject of a future KJS/elobf article) and although only one of the quartet charted, they did and still do generate interest in the ELO fan base for avid vinyl collectors ...

Louis Clark ~ "(per-spek-tiv)n." (1979) ~ JETLP218
Surprising non-charting orchestral outing by the ELO arranger with a little help from his friends including Roy Wood and former Wizzard saxophonist Nick Pentelow.

Violinski ~ "No Cause For Alarm" (1979) ~ JETLP219
Mik Kaminski and his blue violin brigade featuring ex-ELO bassist Mike de Albuquerque crept into the UK Top 50 at #49 with their debut album. Lead single "Clog Dance" (JET136) also made the UK Top 20, peaking at #17.

Wilson Gale & Co. ~ "Gift Wrapped" (1980) ~ JETLP223
ELO cellist Melvyn Gale teamed up with Frank Wilson for this hard to find album with Hugh McDowell also contributing.

Violinski ~ "Stop Cloning About" (1980) ~ JETLP232
Their second album featured "Silent Love" which would likely have been another hit single as Radio 1's "Record of the Week" but for an "account problem" with the Jet label.

It's worth noting that during the Jet Records period between 1975 and 1983, every record released by individual members of ELO (other than those noted above by Mik Kaminski and Violinskidid not trouble the charts. That list includes the solo singles "Doin' That Crazy Thing" (1977) by none other than Jeff Lynne (UP36281/SJET102) and "Let There Be Drums" (JET777) by Bev Bevan! You may also enjoy perusing these elobeatlesforever (elobf) articles on similar subject matter ...

Louis Clark: Get Some Perspektiv
When Jeff Lynne Was Doin' That Crazy Thing
JET777: Bev Bevan's Heavy Headliner
Jet Records Discography

*** Until next "Time" in the elobf universe ... KJS ... 24-Nov-2019 ***

          

Paul Revere Heritage Commission Administrative Assistant

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Paul Revere Heritage Commission Administrative Assistant

           

DEFINITION

Position provides assistance and support services to the Paul Revere Heritage Commission (PRHC). Work includes administering programs and policies; preparing reports and correspondence; responding to inquiries, requests, and complaints; maintaining and updating files and records; preparing for and attending PRHC meetings (and Annual or Special Town Meetings as requested), taking and transcribing minutes of meetings, and providing follow up for meetings; and performing a variety of administrative and support responsibilities as assigned by the PRHC Chairman.

ESSENTIAL FUNCTIONS

The essential functions or duties listed below are intended only as illustrations of the various type of work that may be performed. The omission of specific statements of duties does not exclude them from the position if the work is similar, related, or a logical assignment to the position.

  • Provides administrative, secretarial and clerical assistance to the PRHC; drafts and distributes agenda, prepares for and posts notices and agenda of open meetings and executive sessions consistent with Open Meeting Law, and attends PRHC and (as needed) committee meetings and Annual or Special Town Meetings, takes and transcribes minutes of meetings, and provides follow up for meetings; prepares correspondence and reports; and maintains records for office.
  • Retrieves information from files or other sources to assist Commission or its committees in their deliberations.
  • Helps to prepare slide presentations for PRHC meetings or Annual or Special Town Meetings.
  • Conducts research from online public sources, data banks, museums or third parties on topics helpful to the PRHC.  
  • Schedules and arranges for hearings as needed and informs individuals of hearing information.
  • Schedules use of shared event space on the second floor of the Paul Revere Mill.
  • Maintains and keeps current all information on the PRHC’s home page and Laser Fiche sections on the Town website and social media.
  • Maintains appropriate records of all PRHC expenses and sources of income.
  • Maintains hard copy and online files of all public statements by or relating to the PRHC and the Paul Revere Museum of Discovery & Innovation, including news articles, photographs, video or other source material. 
  • Answers inquiries from the public or forwards inquiries to the appropriate PRHC member for response. 
  • Performs similar or related work as required. 


SUPERVISION RECEIVED

Employee works under the general supervision of the PRHC Chairman. The employee plans and prioritizes work in accordance with standard practices and training. Policy problems or changes in procedures are discussed with the Chairman, but ordinarily the employee plans the work, lays it out and carries it through to completion independently. Work is generally reviewed only for technical adequacy, appropriateness of actions or decisions, and conformance with policy or other requirements; the methods used in arriving at the end result are not usually reviewed in detail. The Chairman provides additional, specific instruction for new, difficult or unusual assignments, including suggested work methods.  The employee refers unusual situations to the supervisor for advice and further instructions. 



ACCOUNTABILITY

The nature of work assures that errors are usually detected in succeeding operations.  Consequences of errors, missed deadlines or poor judgment may include time loss caused by back checking by others and slowdowns in the processing of the work.  Errors are generally confined to a single department, such as billing or accounting errors and/or failure to check a subordinate’s performance.



JUDGMENT

The work involves numerous standardized practices, procedures, or general instructions that govern the work and in some cases may require additional interpretation.  Judgment is needed to locate, select and apply the most pertinent practice, procedure, regulation or guideline.



COMPLEXITY

The work consists of simple, routine or repetitive tasks and/or operations with few variations in well-known or established procedures, as well as tasks that require creativity and resourcefulness in achieving a desired outcome without a fixed process or procedure to guide the work.  



NATURE AND PURPOSE OF CONTACTS

Relationships are primarily with co-workers and the public, involving frequent explanation, discussion or interpretation of practices, procedures, regulations or guidelines in order to render service, plan or coordinate work efforts, or resolve operating problems.  Other regular contacts are with service recipients and employees of outside organizations.  More than ordinary courtesy, tact and diplomacy may be required to resolve complaints or deal with hostile, uncooperative or uninformed persons.  



CONFIDENTIALITY

Employee has access to some confidential information in the performance of his or her duties.



EDUCATION AND EXPERIENCE

Associate Degree in Business Administration is required. Bachelor degree in Business Administration preferred. Candidate should have two (2) years of advanced business or secretarial training, and three (3) years of relevant work experience or an equivalent combination of education and experience.


KNOWLEDGE, ABILITY, AND SKILLS

Knowledge: Knowledge of PRHC regulations, policies and programs and department operations; knowledge of office management principles and practices and computer systems and equipment used by the department.

Abilities:  Ability to manage multiple tasks, meet deadlines, and pay careful attention to details despite interruptions; ability to maintain confidential information; ability to work independently. 

Skills: Administrative, project management, record keeping, bookkeeping, secretarial, research (online/data base), computer (excel, word, power point), organizational, verbal and written communication and customer service skills.



WORK ENVIRONMENT

The work environment involves everyday discomforts typical of offices, with occasional exposure to outside elements. Noise or physical surroundings may be distracting, but conditions are generally not unpleasant.  Incumbent may be required to work beyond normal business hours in response to emergency situations or to attend evening meetings.



PHYSICAL, MOTOR, AND VISUAL SKILLS

Physical Skills

Minimal physical demands are required to perform most of the work.  The work principally involves sitting, with intermittent periods of stooping, walking, and standing.  May be required to lift objects such as files, boxes of papers, office supplies, and office equipment weighing up to 30 pounds. 

Motor Skills

Duties are largely mental rather than physical, but the job may occasionally require minimal motor skills for activities such as moving objects, using office equipment, including but not limited to telephones, personal computers, handheld technology, and other office equipment. 


Visual Skills

Visual demands require routinely reading documents for general understanding and analytical purposes and viewing a computer monitor. 


          

Researchers discover stellar black hole too large for science to explain

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A team of scientists based in China announced the discovery of a stellar black hole so large that science currently lacks an explanation for it.
          

Snakes had legs, cheek bones 100 million years ago

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The discovery of the fossilized remains of an ancient primitive snake species suggests rear-legged snakes living during the Cretaceous Period still had a cheek bone.
          

Efficient and Scalable Functional Dependency Discovery on Distributed Data-Parallel Platforms

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Functional dependencies (FDs) play a very important role in many data management tasks such as schema normalization, data cleaning, and query optimization. Meanwhile, there are ever-increasing application demands for efficient FD discovery on large-scale datasets. Unfortunately, due to huge runtime and memory overhead, the existing single-machine FD discovery algorithms are inefficient for large-scale datasets. Recently, distributed data-parallel computing has become the de facto standard for large-scale data processing. However, it is challenging to design an efficient distributed FD discovery algorithm. In this paper, we present SmartFD, which is an efficient and scalable algorithm for distributed FD discovery. First, we propose a novel attribute sorting-based algorithm framework. Next, to discover all the FDs grouped by a given attribute, we propose an efficient distributed algorithm Attribute-centric Functional Dependency Discovery (AFDD). In AFDD, we design an Fast Sampling and Early Aggregation (FSEA) mechanism to improve the efficiency of distributed sampling and propose a memory-efficient index-based method for distributed FD validation. Moreover, AFDD employs an attribute-parallel method to accelerate the pruning-and-generation of candidate FDs. Furthermore, we propose an adaptive switching strategy between distributed sampling and distributed validation based on the unified time-based efficiency metric. Also, we employ a distributed probing based method to make the switching strategy more accurate. Experimental results on Apache Spark reveal that SmartFD outperforms the state-of-the-art single-machine algorithm HyFD and the existing distributed algorithm HFDD with 3.2×–44.9× and 2.5×–455.7× speedup respectively. Moreover, SmartFD achieves good row scalability and column scalability. Additionally, SmartFD has sub-linear node scalability.
          

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Bones discovered in Valley Road, Fawkham, as forensics team searched building site

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Bones discovered at a building site earlier today are not human, police have now said.

The discovery of what were feared to be human remains, were found at about noon at the site in Valley Road, Fawkham.

Now police have said there are no suspicious circumstances surrounding the find.

Officers have now left the scene and the site has been locked up.

The bones were discovered at a cottage by a worker digging a new road.

A search team who have been looking for missing mum Sarah Wellgreen had been at the location for most of the day.

Andy Saunders from Kent Police said: "Police were called at 12.15pm to a report that bones had been discovered at a building site in Valley Road, Fawkham.

The site has now been locked up
The site has now been locked up

"Officers attended the scene and following inquiries, it has been determined that there is no suspicious circumstances surrounding the discovery."

Read more: All the latest news from Dartford


          

Bluewater waiter found dead in flat above Reliance Fish Bar in Gravesend

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A waiter may have been dead for close to a week before his body was found above a fish and chip shop.

Neighbours in Paolo Corona's bedsit in Queen Street, Gravesend became concerned by a smell coming from his room, an inquest heard today.

Queen Street, Gravesend
Queen Street, Gravesend

The waiter's body was found "in a state of decomposition," at around 5am on September 1 and paramedics were called.

Paramedics called for police assistance after discovering drug paraphernalia next to Mr Corona's body.

A police report filed by Det Sgt Neil Martin revealed the neighbour was "too distressed" to re-enter Mr Corona's bedsit in Queen Street, Gravesend, after making the discovery.

Judging by receipts found in his home, police decided Mr Corona was last seen on August 26.

He was supposed to work a shift at Tapas Revolution in Bluewater that day, but did not show.

A needle and bag of heroin found next to Mr Corona led police to conclude the death was drug related.

The 36-year-old, who was born in Gemona del Friuli in north east Italy, was found to have alcohol, cocaine, and heroin in his system, along with THC, one of the active components of cannabis.

Dr Anna Rycroft said Mr Corona's "widespread, extensive decomposition," made it impossible to take readings of the amount of each drug in his system.

Coroner Roger Hatch said: "Having regard to evidence from the officer I propose to record that the death of Paolo Corona was drug related."

For more information on how we can report on inquests, click here

Read more: All the latest news from Gravesend


          

This *hot* trick can charge an EV battery in just 10 minutes

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Electric cars could make a huge dent in the world’s greenhouse gas emissions. But they still make a tiny 2 percent of cars on the road today. A big speed bump they face is the hour or so it takes to charge. That could change, thanks to a new discovery by Pennsylvania State University researchers. They have come up with a technique to charge lithium battery in just 10 minutes for 200 to 300 miles of driving. An electric car that can be charged in the time it takes to fill a gas tank could jumpstart the EV market. “The…

This story continues at The Next Web
          

Michelle Yeoh Wanted to Do Section 31 Before Star Trek: Discovery Even Aired

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In the flurry of Star Trek news over the past few months, the upcoming Section 31 spinoff starring Michelle Yeoh has been somewhat lost in the shuffle. In a recent interview, some of the lead Trek people talked a bit about how things have been going on that front and shed some light on the show’s development.

Read more...


          

Bilingual All Inclusive Director of Guest Experience Operations - CALA Regional...

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Here’s To Your Journey with Marriott International is the world’s largest hotel company, with more brands, more hotels and more opportunities for associates to grow and succeed. We believe a great career is a journey of discovery and exploration. So, we ask, where will your journey take you? The CALA Regional Office located at 1200 S. Pine Island Road, Plantation, FL 33324 is currently hiring a Bilingual All Inclusive Director of Guest Experience Operations. Responsibilities... DOE
          

Mealey's Litigation Procedure - Discovery In Disability Suit Is Not Warranted, California Federal Judge Determines

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OAKLAND, Calif. - A California federal judge on Nov. 25 denied a disability claimant's request to conduct discovery after determining that the claimant failed to prove that additional evidence is necessary to conduct an adequate de novo review (Natalya Vigdorchik v. Liberty Life Assurance Company of Boston, et al., No. 19-3891, N.D. Calif., 2019 U.S. Dist. LEXIS 204512).
          

Citrus Greening on the Move in Southern California

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A quarantine has been declared following the discovery of citrus greening (HLB) in a single tree in an unincorporated area of San Bernardino County near Montclair, reports the California Department of ...
          

The 2019 ASRS Conference, Part 2

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by Carmen and Loren Seibold  |  25 November 2019  | Dr. Tihomir Lazic. Newbold College “Truth as Koinonia: The Essential Role of the Church in God’s Self-Revelation” This paper suggests the Trinity as a way of modeling the discovery of truth in the church.  While Adventists are proud of themselves for having such a dynamic […]
          

Новые телеканалы кабельного телевидения в г. Кемерово!

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Уважаемые абоненты кабельного телевидения в г. Кемерово!
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4 декабря 2019г. в перечне телеканалов аналогового кабельного телевидения произойдут изменения. На смену телеканалам Discovery, Inc.* придут новые телеканалы спортивной и познавательной тематики, а также телеканалы Дом кино и Мама.

          

2018 27.500 Chilometri 34.600 euro

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Land Rover Discovery 2. 0 TD4 SE AUTOM. 180 CV Usato anno 2018 Fuoristrada / SUV 27500 km Autoradio Servosterzo Alzacristalli Elettrici Regolazione...
          

2019 15.500 Chilometri 37.700 euro

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Land Rover Discovery 2. 0 TD4 SE DYNAMIC AUTOM. (180 CV ) Usato anno 2019 Fuoristrada / SUV 15500 km Autoradio Servosterzo Alzacristalli Elettrici...
          

2018 19.900 Chilometri 44.900 euro

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Land Rover Discovery 5 2. 0 SD4 SE 4X4 AUTOM. (241CV) PANORAMA LED Usato anno 2018 Fuoristrada / SUV 19900 km Autoradio Servosterzo Alzacristalli...
          

Kommentar zu Holger Strohm / Demokratie in Gefahr / Was ist aus Deutschland geworden? von muktananda13

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@Drusius DIE WELT Älteste Schriftzeichen der Welt in China gefunden Veröffentlicht am 23.04.2003 Von wom 8600 Jahre alte Ritzungen in Schildkrötenpanzern Anzeige Forscher des Brookhaven National Laboratory in New York haben bei Ausgrabungen in Jiahu in der chinesischen Provinz Henan Grabbeigaben gefunden, die 8600 Jahre alte Schriftzeichen enthalten. Es handelt sich um Schildkrötenpanzer mit Einritzungen. Damit wären diese Zeichen mehr als 2000 Jahre älter als Schrifttafeln aus Mesopotamien (im heutigen Irak). Diese galten bislang als älteste Belege für schriftliche Dokumente. Die Archäologen fanden auf den Schildkrötenpanzern in 24 Gräbern insgesamt elf verschiedene Zeichen. Sie zeigen Symbole, die unter anderem sehr stark an die Darstellung von Augen und Fenstern erinnern. Die Forscher halten diese Symbole und andere Ritzungen für Schriftzeichen, weil sie auch jenen Zeichen stark ähneln, die Jahrtausende später während der Shang-Dynastie genutzt wurden und für "Augen" und "Fenster" standen sowie für die Zahlen acht und 20. Erstaunt und etwas verunsichert sind die Forscher allerdings durch die Tatsache, dass zwischen den jetzigen Funden und der Shang-Kultur 5000 Jahre ohne bekannte Schriftzeichen liegen. © Axel Springer SE. Alle Rechte vorbehalten. AUßERDEM: Tontafeln von Tărtăria Denkmal nahe der Fundstätte. Übersetzung der Inschrift: Tărtăria 5500 v.Chr.: Die erste schriftliche Nachricht in der Geschichte der Menschheit Die Tontafeln von Tărtăria sind drei kleine Tontafeln (möglicherweise Amulette), die im Jahre 1961 in der Ortschaft Tărtăria entdeckt wurden, die heute ein Teil der Gemeinde Săliștea (Kreis Alba) in Rumänien ist. Sie zeigen Vinča-Zeichen, die wichtigste regionale Variante des Donauschrift genannten Zeichensystems, das auch als alteuropäische Schrift bezeichnet wird (auch wenn die Einordnung des Zeichensystems als Schrift umstritten ist). Die Zeichen werden der prähistorischen Vinča-Kultur zugeordnet. Die Tontafeln werden auf etwa 5500–5300 v. Chr. datiert,[1] wurden jüngst allerdings als mögliche Fälschung bezeichnet.[2] Sie werden im Muzeul Național de Istorie a Transilvaniei (Nationalmuseum der Geschichte Siebenbürgens) in Cluj-Napoca (Klausenburg) verwahrt.[3] Inhaltsverzeichnis 1 Die Entdeckung 2 Literatur 3 Weblinks 4 Einzelnachweise Die Entdeckung 1875 entdeckten Archäologen bei Ausgrabungen in Turdaș viele Gegenstände mit bisher unbekannten Symbolen. 1961 entdeckte eine Forschergruppe des Nationalmuseums in Cluj unter der Leitung von Nicolae Vlassa die drei hier beschriebenen Tontafeln.[4] Einer 2013 veröffentlichten These zufolge könnten die Tontafeln von Tărtăria eine Fälschung sein.[2] Literatur A. Falkenstein: Zu den Tafeln aus Tartaria, in: Germania 43 (1965) 269–273. Harald Haarmann: Writing from Old Europe to Ancient Crete - A Case Study of Cultural Continuity, in: The Journal of Indo-European Studies 17 (1990) 251-277. Dominique Jongbloed: Civilisations antédiluviennes. Bilan de 2.500 ans de recherches, Alphée ed. 2011. Gheorghe Lazarovici, Fl. Drasovean & Z. Maxim 2000 The Eagle – the Bird of death, regeneration resurection and messenger of Gods. Archaeological and ethnological problems. Tibiscum, 57–68 Gheorghe Lazarovici, Fl. Drasovean & Z. Maxim 2000 The eye – symbol, gesture, expresion.Tibiscum, 115–128 Gheorghe Lazarovici, Marco Merlini: New archaeological data referring to Tărtăria tablets, in: Documenta Praehistorica XXXII, Department of Archeology Faculty of Arts, University of Ljubljana, Ljubljana 2005, S. 205–219 (online, PDF). Marco Marlini: La scrittura è natta in Europa?, Roma 2004. Marco Merlini: The Sacred Cryptograms from Tărtăria. Unique or Widespread Signs? Putting the Asserted Literate Content of the Tablets under Scrutiny, in: Fifty Years of Tărtăria Excavations. Festschrift in Honor of Gheorghe Lazarovici, Sebastopol/Kalifornien 2014, S. 73–119. Janos Makkay: The Late Neolithic Tordos Group of Signs. Alba Regia 10 (1969) 9–50. Janos Makkay: Early Stamp Seals in South-East Europe. Budapest 1984. Emilia Masson: L' écriture dans les civilisations danubiennes néolithiques. Kadmos 23,2 (1984) 89-–123. Zoia Maxim: Neo-eneoliticul din Transilvania. Bibliotheca Musei Napocensis 19. Cluj-Napoca 1997. Marco Marlini, Gheorghe Lazarovici: Settling discovery circumstances, dating and utilization of the Tărtăria tablets (PDF; 10,8 MB). In: Acta Terrae Septemcastrensis. Band: VII. 2008. Lucian Blaga University of Sibiu. Vladimir Milojčić: Die Tontafeln von Tartaria (Siebenbürgen), und die Absolute Chronologie des mitteleuropäischen Neolithikums, in: Germania 43 (1963) 266–268. Iuliu Paul: Vorgeschichtliche untersuchungen in Siebenburgen. Alba Iulia 1918 (Inhaltsverzeichnis online). Nicolae Vlassa: Contribuții la Problema racordării Neoliticul Transilvaniei, 1976, S. 28–43, fig. 7–8. Winn Milton McChesney: The signs of the Vinc̆a Culture, University Microfilms, 1973. Shan M. Stroemfeld Winn: Pre-writing in Southeast Europe: The Sign System of the Vinča culture. BAR 1981. Weblinks Commons: Tontafeln von Tărtăria – Sammlung von Bildern, Videos und Audiodateien Fundstücke der Vinča-Kultur (Memento vom 6. Juni 2009 im Internet Archive) Vinca symbols bei omniglot.com, inkl. Font ein weiterer Font (Vinča symbols) Eric Lewin Altschuler: The Number System of the Old European Script Einzelnachweise Harald Haarmann: "Geschichte der Schrift", C.H. Beck, 2002, ISBN 3-406-47998-7, S. 20. Erika Qasim: Die Tărtăria-Täfelchen – eine Neubewertung. In: Das Altertum, ISSN 0002-6646, Bd. 58, 4 (2013), S. 307–318. Photos from Romania – The Tartaria tablets. www.romaniaphotos.ro, abgerufen am 29. März 2015 (englisch). Alasdair W. R. Whittle, Europe in the Neolithic: The Creation of New Worlds, Cambridge University Press, 1996, S. 101.
          

Gene discovery in fruit flies could help search for new treatments for mitochondrial disease

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Scientists have identified a protein in fruit flies that can be targeted to reverse the effects of disease-causing mutations in mitochondrial genes. The discovery could provide clues about how to counteract human mitochondrial diseases, for which there is currently no cure.
          

Silencing retroviruses to awaken cell potential

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Silencing of retroviruses in the human genome is a crucial step in the production of induced pluripotent stem cells (iPSCs) from somatic cells. Researchers led by a team from the University of Tsukuba have now identified a protein that controls retrovirus silencing, allowing the production of high quality iPSCs that could be used in applications ranging from stem cell therapy and organ regeneration to drug discovery.
          

Land Rover Discovery Td5 Workshop

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Land Rover Discovery Td5 Workshop
          

World's oldest comma shrimp was way ahead of the curve

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Scientists have discovered the world's oldest "comma" shrimp, a tiny crustacean shaped like its punctuation namesake. The 90-million-year-old creature fills in a major evolutionary gap for a family of marine animals now found in abundance around the planet, according to researchers from Yale and the University of Alaska. The discovery appears in the journal Proceedings of the Royal Society B. Eobodotria muisca [Credit: Javier...

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Black hole nurtures baby stars a million light years away

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Black holes are famous for ripping objects apart, including stars. But now, astronomers have uncovered a black hole that may have sparked the births of stars over a mind-boggling distance, and across multiple galaxies. Credit: X-ray: NASA/CXC/INAF/R. Gilli et al.; Radio NRAO/VLA; Optical: NASA/STScIIf confirmed, this discovery, made with NASA's Chandra X-ray Observatory and other telescopes, would represent the widest reach ever seen...

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Modelling diastolic dysfunction in induced pluripotent stem cell-derived cardiomyocytes from hypertrophic cardiomyopathy patients

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Abstract
Aims
Diastolic dysfunction (DD) is common among hypertrophic cardiomyopathy (HCM) patients, causing major morbidity and mortality. However, its cellular mechanisms are not fully understood, and presently there is no effective treatment. Patient-specific induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) hold great potential for investigating the mechanisms underlying DD in HCM and as a platform for drug discovery.
Methods and results
In the present study, beating iPSC-CMs were generated from healthy controls and HCM patients with DD. Micropatterned iPSC-CMs from HCM patients showed impaired diastolic function, as evidenced by prolonged relaxation time, decreased relaxation rate, and shortened diastolic sarcomere length. Ratiometric Ca2+ imaging indicated elevated diastolic [Ca2+]i and abnormal Ca2+ handling in HCM iPSC-CMs, which were exacerbated by β-adrenergic challenge. Combining Ca2+ imaging and traction force microscopy, we observed enhanced myofilament Ca2+ sensitivity (measured as dF/Δ[Ca2+]i) in HCM iPSC-CMs. These results were confirmed with genome-edited isogenic iPSC lines that carry HCM mutations, indicating that cytosolic diastolic Ca2+ overload, slowed [Ca2+]i recycling, and increased myofilament Ca2+ sensitivity, collectively impairing the relaxation of HCM iPSC-CMs. Treatment with partial blockade of Ca2+ or late Na+ current reset diastolic Ca2+ homeostasis, restored diastolic function, and improved long-term survival, suggesting that disturbed Ca2+ signalling is an important cellular pathological mechanism of DD. Further investigation showed increased expression of L-type Ca2+channel (LTCC) and transient receptor potential cation channels (TRPC) in HCM iPSC-CMs compared with control iPSC-CMs, which likely contributed to diastolic [Ca2+]i overload.
Conclusion
In summary, this study recapitulated DD in HCM at the single-cell level, and revealed novel cellular mechanisms and potential therapeutic targets of DD using iPSC-CMs.

          

#Casting marito e moglie per nuovo programma tv su #Discovery

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Casting nuovo programma televisivo in onda prossimamente su rete nazionale. AAA PER UN NUOVO PROGRAMMA SU CANALE DISCOVERY CERCASI MARITO E MOGLIE DISPOSTI A DIVERTIRSI E A FARE UNA NUOVA ESPERIENZA...
          

Emergent Quasicrystalline Symmetry in Light-Induced Quantum Phase Transitions

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The discovery of quasicrystals with crystallographically forbidden rotational symmetries has changed the notion of the ordering in materials, yet little is known about the dynamical emergence of such exotic forms of order. Here we theoretically study a nonequilibrium cavity-QED setup realizing a zero-temperature quantum phase transition from a homogeneous Bose-Einstein condensate to a quasicrystalline phase via collective superradiant light scattering. Across the superradiant phase transition, collective light scattering creates a dynamical, quasicrystalline optical potential for the atoms. Remarkably, the quasicrystalline potential is “emergent” as its eightfold rotational symmetry is not present in the Hamiltonian of the system, rather appears solely in the low-energy states. For sufficiently strong two-body contact interactions between atoms, a quasicrystalline order is stabilized in the system, while for weakly interacting atoms the condensate is localized in one or few of the deepest minima of the quasicrystalline potential. F. Mivehvar et al., Phys. Rev. Lett. 123, 210604 (2019)
          

Stimulation of Glioma-Associated Microglia/Macrophages effector phagocytic synapse towards tumor clearance in glioma /

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Glioblastoma (GBM) es el tumor más agresivo dentro de la clasificación de gliomas y actualmente no tiene cura. Dado que hasta el 30% de las células en GBM son microglia y macrófagos (GAMMs desde ahora, por sus siglas en ingles), decidimos estudiarlos para ayudar en el diseño de posibles futuras inmunoterapias. El primer gran descubrimiento de esta tesis es la presencia de GAMM en las pseudo-empalizadas (PPs, por sus siglas en inglés) in GBM humano. Estas estructuras se cree que pueden contribuir a la capacidad de invasión del tumor, por lo que el papel de los GAMM en este microambiente puede ser crucial. En concreto, describimos que los GAMMs viajan a través de las PPs hacia su foco necrótico, de forma inversa a las células tumorales. Además, los GAMMs parece que ganan persistencia celular, es decir que viajan de forma directa, bajo las condiciones hipóxicas de las PPs y se desplazan de manera haptotáctica, siendo las fibras GFAP+ su sustrato para avanzar. Al llegar al área necrótica, cambian su fenotipo y fagocitan material del tumor, incluyendo fragmentos GFAP+ y núcleos celulares. En segundo lugar, en cultivos celulares hemos inducido la translocación de NF-κB p65 para aumentar la facogitosis de células de glioma (C6) por parte de microglia primaria de rata. Además, por medio de líneas celulares inmortalizadas (BV-2 y GL261) hemos descrito una serie de supuestos pasos que pueden ser importantes en el proceso de fagocitosis, así como la distribución de determinados receptores (CD11b y CD16/32) durante estas etapas. Asimismo, describimos la distribución de Iba-1 en los procesos de interacción fagocítica en modelos animales de glioma. Por último, hemos probado dos estrategias de inmunoterapia en un modelo murino de GBM (ratones C57/BL6 inyectados con células GL261 intracranealmente), descubriendo que estas inmunoterapias tienen efectos distintos: mientras la neutralización de CD47 pareció no ser efectiva, neutralizar SIRP1α parece ser beneficiosa. Así, los animales del grupo denominado CD47 no mostraban un aumento de su supervivencia comparados con los ratones control, incluso mostraban pérdida de peso, indicador de que la terapia pueda producir efectos secundarios sistémicos. Por otro lado, el bloqueo de SIRP permitió el incremento del peso corporal de los animales durante el experimento, y, de hecho, disminuyó el número de células en el centro del tumor incrementando la capacidad fagocítica de los GAMMs en las zonas periféricas de invasión, sin interferir en su capacidad de infiltrar en el tumor. En conclusión, esta tesis contribuye a una mejor comprensión de la función de los GAMMs en GBM y su capacidad fagocítica intrínseca, posiblemente ayudando al desarrollo de nuevas herramientas terapéuticas para luchar contra este tumor. ; Glioblastoma (GBM) is the most aggressive form of glioma and currently has no cure. Given that around 30% of the cells within the tumor are microglia/macrophages (glioma- associated microglia/macrophages or GAMM from now on), we decided to study them in order to shed light in possible future immunotherapies. The first discovery during this investigation was the presence of GAMM in pseudopalisades (PPs) of human GBM. These structures are thought to be very important in the contribution of the tumor invasiveness, therefore the knowledge of the role of GAMMs here might be crucial. Particularly, GAMMs were found to be traveling through the PPs towards the necrotic focus, contrasting with the tumor cells. Moreover, the myeloid cells seem to gain cellular persistence with the hypoxic gradient and travel in a haptotactic manner using the gradient of glioma cells as a cue. When they reach the necrotic focus, they shift their phenotype and phagocytose tumor material, including GFAP+ fragments and nuclei. Secondly, by means of cell cultures we achieved to translocate p65 NF-κB and promote phagocytosis of tumor glioma cells (C6) by primary microglia. Moreover, using cell lines (BV-2 and GL261) we described the putative steps of phagocytosis and the distribution of some receptors (CD11b and CD16/32) involved in the process of phagocytosis. Importantly, the distribution of Iba-1 in interacting GAMMs was also defined in the animal models. Finally, we tested two immunotherapy strategies in a immunocompetent GBM animal model (C57/BL6 intracraneally inoculated with GL261 cells), and discovered that both immunotherapies have different outcomes: while CD47 neutralizing antibody seemed to be non-effective, neutralizing SIRP1α had a beneficial outcome. This way, anti-CD47 treated animals did not have any increase on survival rate than control groups; and they showed decreased bodyweight throughout the experiment, suggesting that the therapy had some systemic side effects. On the other hand, blocking SIRP1α allowed the increase of the bodyweight of the animals throughout the experiment, and decreased the cellularity of the tumor core by increasing the phagocytic activity of GAMM at the peripheral area of tumor invasion without interfering in their infiltration capacity. In all, this thesis contributes to a better understanding of the role of GAMMs in GBM and the intrinsic phagocytic capacity they can play, possibly helping in the development of immunotherapeutic tools to fight this fatal tumor.
          

Discovery 690 Service

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Discovery 690 Service
          

First Theme Park on the West Coast Powered by Solar is Six Flags Discovery Kingdom

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Sage CRM 2019 R2: Multiple workflow paths for the same entity

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This article has been prompted by a question from a customer. They need for their users to capture Opportunity 'quick facts' to start the sales process. In their case, their contacts may wish to buy a 'product', a 'service' or a 'combined' solution. Depending on the prospect's interest then the sales process needs to go down a distinct path with other information needed to be captured. And it may be possible to 'jump' to another workflow later on.

I've assumed that for this article you know a little about Sage CRM's workflow processes. The Sage Support & Training YouTube channel has some good short videos that explain workflow.

We have perhaps 3 basic options for the workflow design at this point.

  • Single Branched Workflow Process
    • This would start the workflow with a single Primary Rule that governs the initial creation of the opportunity. The workflow would then branch depending on the data that was captured. This approach could become very complex very quickly.

  • Separate Workflow Processes (Primary Rules)
    • This would present a user with 3 separate options to create and manage the opportunity. But it would require the user to have foreknowledge of the process that needs to be followed.
  • Separate Workflow Processes (Transition Rules)
    • This option doesn't use workflow to create the opportunity but once the opportunity is captured with the key information then the opportunity can be attached to a particular workflow.

Sage CRM's supports the idea of branched workflow but in this case, where key information needs to be quickly captured and that key information needs to be used to determine the workflow it is most appropriate to use 3 separate workflows.

This approach does not use a 'primary rule' to start the workflow but rather 3 separate workflows that each start with a Transition Rule. This means that the data would be captured using the basic New Opportunity page. The screens that make up this page (OpportunityFilterBox, OpportunityDetailBox etc) can be simplified to capture on the key information that the customer needs.

Once the opportunity record is created and saved it is not yet attached to a workflow process (The oppo_workflowid field would be null). But transition rules within the workflow definition can be linked to the 'start' state and so be able to be visible to a user looking at an opportunity record not yet associated with a workflow.

What that means is that potentially 3 separate buttons could appear on the new Opportunity Summary screen inviting the user to follow either the 'Software' or 'Services' or 'Combined' sales workflows. (And example of this is provided in the default Opportunity Workflow that causes Accept or Reject buttons to appear for new opportunities converted from Leads).

But if the aim for the customer is to only be presented with a single option then this could be done because the transition rules have a JavaScript condition box that can look at the data in the record and see whether the conditions that allow the button to display are satisfied. So if in the 'oppo_saletype' field the user has selected 'Software' then only the workflow button for Software Sales workflow would be displayed.

It is possible to jump workflows so if the user has made a mistake and it turns out that after further discovery the prospect needs a 'Combined' solution then this can be made to reset the workflow and go down another path.


          

The latest Christmas must-haves on Air France Shopping

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In preparation for the holiday season, Air France is unveiling its Christmas selection to exclusively discover on airfranceshopping.com. The little globetrotters' travel kit. To inspire a desire for discovery and adventure, Air France Shopping is teaming up this winter with Bonton, French kids clothing brand, and unveils the ideal travel kit for little globetrotters. This small suitcase for kids comprises a night mask, a baggage tag, a soft blanket and a set of storage pouches. In a n...

Read the full story at https://www.webwire.com/ViewPressRel.asp?aId=250699


          

Agilent Receives Multiple Life Science Industry Awards for Innovation

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Agilent Technologies, Inc. (NYSE: A) announced today that it has received two Life Science Industry Awards (LSIA) for 'Most Innovative New Products in 2019' from BioInformatics Inc. Since 2002, the LSIA have recognized manufacturers of the 'tools of science' that help advance biological research and drug discovery. The Agilent products were the Magnis NGS Prep System, which received a Silver Award in the genomics category, and the xCELLigence RTCA eSight, which received a Bronze Award...

Read the full story at https://www.webwire.com/ViewPressRel.asp?aId=250698


          

Hospitality & Tourism: Host/Hostess - Gaylord Texan Resort & Convention Center (17001TDF) - Grapevine, Texas

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Heres To Your Journey with Gaylord Gaylord is one of Marriott Internationals 30 renowned hotel brands. As the worlds leading hospitality company, we offer unmatched opportunities for associates to grow and succeed. We believe a great career is a journey of discovery and exploration. The Gaylord Texan Resort & Convention Center, located at 1501 Gaylord Trail, Grapevine, TX, 76051 is currently hiring a Host/Hostess. Responsibilities include: Greet guests and determine the number in their party. Seat guests by finding a clean, available table; pulling out chairs; placing clean/current menu in front of guest, etc. Guide guests through the dining rooms and provide any needed assistance. Move and arrange tables, chairs, and settings and organize seating for groups with special needs. Ensure place settings are appropriate and each guest has a napkin, clean silverware, and any other item that is part of the standard place setting. Check menus to ensure they are current, clean, plentiful, and wrinkle-free. Maintain cleanliness of work areas throughout the day, practicing clean-as-you-go procedures. Monitor dining rooms for seating availability, service, safety, and well being of guests. Follow all company and safety and security policies and procedures; report accidents, injuries, and unsafe work conditions to manager; and complete safety training and certifications. Ensure uniform and personal appearance are clean and professional, maintain confidentiality of proprietary information, and protect company assets. Welcome and acknowledge all guests according to company standards. Speak with others using clear and professional language, and answer telephones using appropriate etiquette. Develop and maintain positive working relationships with others, support team to reach common goals, and listen and respond appropriately to the concerns of other employees. Ensure adherence to quality expectations and standards. Stand, sit, or walk for an extended period of time. Move, lift, carry, push, pull, and place objects weighing less than or equal to 10 pounds without assistance. Perform other reasonable job duties as requested by Supervisors. To apply now, go to: marriott.taleo.net/careersection/2/jobdetail.ftl?job=17001TDF Marriott International is consistently recognized as an employer of choice globally by FORTUNE magazine, DiversityInc and Great Places to Work Institute, among others. Visit marriott.com/careers to learn more about our workplace culture and career opportunities. So, we ask, where will your journey take you? Marriott International is an equal opportunity employer committed to hiring a diverse workforce and sustaining an inclusive culture. Marriott International does not discriminate on the basis of disability, veteran status or any other basis protected under federal, state or local laws. ()
          

Patient Care Programs Coordinator ~ Vanderbilt Eye Institute | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient
          

New 2020 Online Collage Workshop

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START 2020 WITH A NEW ONLINE CREATIVE COLLAGE WORKSHOP

Start the new year off with a new online collage workshop hosted by artist and author Randel Plowman. Whether it's gaining a new skill level or technique, challenging yourself artistically or simply seeing what dedication and commitment can produce, this workshop is for you. This 52 week long workshop is a personal journey that can offer an opportunity for self-discovery and personal growth. During this online collage workshop participants will be challenged to create a series of collages every week for the next 52 weeks. 
During this year-long online collage workshop participants can work at their own pacewhile sharing their work with others in the group, as we move along from project to project. Those taking the course will be presented with a weekly theme or technique to enhance artistic skills and help with overall technique and design skills. Personal weekly feedback on each week's work will be given.

Some things featured in this workshop
  • weekly prompts and exercises
  • downloadable video demos and projects
  • ability to share your work with others in the group
  • weekly feedback on each project
  •  online group exhibit based on a title or theme
  • group collage exchange
  • online classroom
  • demos

Some projects featured include: Week 5: Exploring Color Relationships, Week 16: Kurt Schwitters Style Collage, Week 18: Creating A Montage Using Dry Glue Technique, Week 21: Art of DécollageWeek 38: Tarot Card Collage, Week 47: Picture Consequence Exchange and more.  

This new year long online workshop starts Saturday, JANUARY  18, 2020 and will continue through January 25, 2021The workshop is only $180. A basic material list will be provided after signing up.

Space is limited for this workshop, so sign up early.   

Randel Plowman received his M.F.A. in printmaking from University of Wisconsin-Madison and his B.F.A. from Northern Kentucky University. He has exhibited in solo and juried exhibitions throughout the United States; in addition, his work appears in many public and private collections in North America and abroad, his work has been cited in numerous publications, including The New York Times and USA Today; been featured in The Paris Review, How Designmagazine, Artist Magazine and Somerset Studio. He is the author of two books, Masters: Collage, and The Collage Workbook: How To Get Started And Stay Inspired
Have a question or comment? Contact me at randelplowman@hotmail

Price $180

Cyber Monday Special ! Save $20 

Only $160
 

          

Black Friday Science-Geek Deals: The Best Gifts for the Awesome Nerds in Your Life

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Here's a look at some of Live Science's favorite Amazon deals for that science geek in your life, from a curious child to a spouse who can't get enough of the Discovery Channel.
          

18,000-Year-Old Puppy Discovered in Siberian Permafrost

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By Mandy Froelich / Truth Theory Scientists are puzzled by a recent discovery in Siberia. An 18,000-year-old puppy, believed to be just two months old when […]

The post 18,000-Year-Old Puppy Discovered in Siberian Permafrost appeared first on TruthTheory.


          

Astronomy in Shakespeare: How Many of His Plays Were Influenced by the Stars

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comet shooting across the galaxy

Read Time: 5 minutes Why would Shakespeare be interested in the stars? He lived in a time of great astronomical discovery. Which plays do you think reference the stars?

The post Astronomy in Shakespeare: How Many of His Plays Were Influenced by the Stars appeared first on Schooled By Science.


          

Article: Q&A with Tyler Treat on Microservice Observability

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Tyler Treat attempts to disambiguate the concepts of Observability and Monitoring. He discusses how the complexity of elastic systems produces more unknowns that require a discovery-based approach. InfoQ recently sat down with Treat to discuss the topics of observability and monitoring, and he shares some challenges and best practices when introducing observability concepts.

By Tyler Treat, Matt Campbell
          

Research Associate, Protein Purification, Discovery Biology - IGM Biosciences - Mountain View, CA

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Our lead product candidate, IGM-2323, is a bispecific T cell engaging IgM antibody targeting CD20 and CD3, and we plan to initiate a Phase 1 clinical trial for…
From IGM Biosciences - Sun, 01 Dec 2019 15:17:23 GMT - View all Mountain View, CA jobs
          

Star Trek - serial o Sekcji 31. Na jakim etapie są prace nad spin-offem Discovery?

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W sieci pojawiły się nowe informacje odnośnie zapowiadanego spin-offa serialu Star Trek: Discovery. to serial z 2017 roku, który przedstawił nam postać Philippy Georgiou (w tej roli ). To właśnie ona będzie główną bohaterką zapowiedzianego jakiś czas temu spin-offa, który nie ma jeszcze oficjalnego tytułu. Wiemy jedynie, że całość ma traktować o Sekcji 31, czyli tajnej organizacji używającej...

Zobacz pełną treść wpisu w serwisie naEKRANIE.pl


          

Post Doctoral Fellow | Eisai Inc.

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Cambridge, Massachusetts, Current Postdoctoral Fellowship Opportunities Successful translation of findings from analysis of human data into the wet lab and back is a foundation of G2D2’s approach to drug discovery. A particula
          

Podcast Strategies For Pandora - The Podcast Report Episode #150

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If you have no plan for Podcast discovery, don’t complain if your Podcast isn’t discovered.

Pandora just might be able to help with that.  Even if it doesn't, you still need to pay attention.  

Shownotes links, conversation and more here - http://ThePodcastReport.com/150.

Pandora now does Podcasts - and Paul Colligan examines what this means to Podcasting, and his clients, on this episode (150) of The Podcast Report.

If you want to listen to the full episode, you'll have to visit http://ThePodcastReport.com/Pandora on a mobile device.

Want the Top Ten List - send "TopTen" to (503) 966 8066.

It's pretty exciting to have this Pandora only episode of The Podcast Report.  If you get a chance, please consider telling someone about it. 


          

Exxon knew — and so did coal

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This story was originally published by HuffPost and is reproduced here as part of the Climate Desk collaboration.

“Exxon knew.” Thanks to the work of activists and journalists, those two words have rocked the politics of climate change in recent years, as investigations revealed the extent to which giants like ExxonMobil and Shell were aware of the danger of rising greenhouse gas emissions even as they undermined the work of scientists.

But the coal industry knew, too — as early as 1966, a newly unearthed journal shows.

In August, Chris Cherry, a professor in the Department of Civil and Environmental Engineering at the University of Tennessee, Knoxville, salvaged a large volume from a stack of vintage journals that a fellow faculty member was about to toss out. He was drawn to a 1966 copy of the industry publication Mining Congress Journal; his father-in-law had been in the industry and he thought it might be an interesting memento.

Cherry flipped it open to a passage from James R. Garvey, who was the president of Bituminous Coal Research Inc., a now-defunct coal mining and processing research organization.

“There is evidence that the amount of carbon dioxide in the earth’s atmosphere is increasing rapidly as a result of the combustion of fossil fuels,” wrote Garvey. “If the future rate of increase continues as it is at the present, it has been predicted that, because the CO2 envelope reduces radiation, the temperature of the earth’s atmosphere will increase and that vast changes in the climates of the earth will result.”

“Such changes in temperature will cause melting of the polar icecaps, which, in turn, would result in the inundation of many coastal cities, including New York and London,” he continued.

Cherry was floored.

“It pretty well described a version of what we know today as climate change,” said Cherry. “Increases in average air temperatures, melting of polar ice caps, rising of sea levels. It’s all in there.”

In a discussion piece immediately following Garvey’s article, Peabody Coal combustion engineer James R. Jones noted that the coal industry was merely “buying time” before more air pollution regulations came into effect. “We are in favor of cleaning up our air,” he wrote. “Everyone can point to examples in his own community where something should be done. Our aim is to have control that does not precede the technical knowledge for compliance.”

Climate change is not Cherry’s area of study, but he was struck by how the tone of the articles differed from the way many fossil fuel companies talk about climate change today. Rather than engage in denial, the articles offered a fairly straightforward acknowledgment of the emerging science. (This reporter is also a writer for UT’s Tickle College of Engineering, where Cherry teaches.)

As Cherry did some of his own digging, he soon realized his discovery could be the first evidence that the coal industry was aware of the impending climate crisis more than half a century ago — a finding that could open mining companies to the type of litigation that the oil industry is now facing.

Decades of denial

While Peabody Energy, the largest private-sector coal company in the world and the largest producer of coal in the U.S., now acknowledges climate change on its website, it has been directly and indirectly involved in obfuscating climate science for decades. It funded dozens of trade, lobbying, and front groups that peddled climate misinformation, as The Guardian reported in 2016.

As recently as 2015, Peabody Energy argued that carbon dioxide was a “benign gas essential for all life.”

“While the benefits of carbon dioxide are proven, the alleged risks of climate change are contrary to observed data, are based on admitted speculation, and lack adequate scientific basis,” the company wrote in a letter that year to the White House Council on Environmental Quality.

At the heart of big coal’s denial campaign was Fred Palmer, who served as Peabody’s senior vice president of government relations from 2001 to 2015. In 1997, Palmer founded the Greening Earth Society, a now-defunct industry front group that argued that burning fossil fuels was good for the planet. The group was based in the same office as the Western Fuels Association, a consortium of coal suppliers and coal-fired utilities that Palmer also ran.

“Every time you turn your car on and you burn fossil fuels and you put CO2 into the air, you’re doing the work of the Lord,” Palmer told a Danish documentary team in 1997. “That’s the ecological system we live in.”

Asked for comment, a Peabody spokesperson told HuffPost:“Peabody recognizes that climate change is occurring and that human activity, including the use of fossil fuels, contributes to greenhouse gas emissions. We also recognize that coal is essential to affordable, reliable energy and will continue to play a significant role in the global energy mix for the foreseeable future. Peabody views technology as vital to advancing global climate change solutions, and the company supports advanced coal technologies to drive continuous improvement toward the ultimate goal of near-zero emissions from coal.”

Palmer, who did not respond to HuffPost’s request for comment, continues to carry the torch. He now works as an energy policy adviser to The Heartland Institute, a Chicago-based think tank whose climate denial is so severe that even ExxonMobil abandoned funding it and its climate denial efforts a decade ago. In 2011, leaked memos showed that the institute paid contrarian scientists like Craig Idso, founder of the Center for the Study of Carbon Dioxide and Global Change, $11,600 a month to promote carbon dioxide as beneficial to the environment.

The group sits at the heart of a broader right-wing misinformation network funded in large part by hedge fund billionaire Robert Mercer and his daughter, Rebekah, both Republican mega-donors who backed President Donald Trump and financed projects such as Breitbart News and Cambridge Analytica, the data firm considered key to Trump’s 2016 win. Palmer’s daughter, Downey Magallanes, was a top policy adviser at Trump’s Interior Department before joining oil giant BP in September 2018.

All of this was taking place well after climate change had become a commonly understood idea in the scientific community. A 1965 report from President Lyndon Johnson’s Science Advisory Committee was the first from the White House to address climate change (and is likely what precipitated the Mining Congress Journal article). “The climate changes that may be produced by the increased CO2 content could be deleterious from the point of view of human beings,” it warned. In 1988, NASA scientist James Hansen testified to Congress about what was then known as the “greenhouse effect.” And in 1992, the United Nations established the Framework Convention on Climate Change, an international treaty to begin addressing the problem.

But as this consensus emerged, so too did a wave of industry-funded climate denial via vast, shadowy networks of front groups, public relations campaigns, and scientists for hire.

Pulling back the curtain

In 2015, journalists at InsideClimate News, the Los Angeles Times, and Columbia University exposed internal ExxonMobil documents showing that the company’s scientists had a deep understanding of climate change even as Exxon worked publicly to downplay that science.

Twenty state attorneys general launched an “Exxon Knew” campaign, which eventually led to communities across the country filing at least 14 legal challenges against Exxon and other fossil fuel companies. One lawsuit, from the New York state attorney general’s office, went to trial on October 22 and focuses on how the company accounted for the costs of potential future regulations on climate change. The Massachusetts attorney general filed another suit on October 24, this time claiming the company had engaged in deceptive advertising and misled investors about the systemic financial risks to its business posed by fossil fuel-driven climate change. Earlier this month, two of Hawaii’s biggest municipalities sued Exxon and other big oil companies to recoup the costs of adapting to rising seas and more violent storms.

Evidence of what fossil fuel companies knew about climate change and when is critical to the legal strategy of those seeking damages for carbon dioxide emissions. If fossil fuel companies were aware of their products’ harmful effects on the planet, they could be held liable for damages.

Legal liability boils down to four factors, said David Bookbinder, chief counsel for the Niskanen Center, which is representing counties in Colorado that have filed suits: one, whether the defendants knew that their products would cause climate change; two, what they told or did not tell the public about the consequences of using their products; three, the extent of injuries caused by climate change; and four, whether the defendants’ actions have led to a portion of those injuries. What the plaintiffs in these suits can prove remains to be seen.

What we do know is that coal, when burned, has by far the biggest climate footprint of any fossil fuel, producing more carbon dioxide per unit than oil or gas. In the U.S. alone, coal produced 65 percent of the power sector’s planet-warming emissions. The 1966 article in the Mining Congress Journal certainly raises questions about what the coal industry knew at the time.

Robert Brulle, a professor emeritus of sociology and environmental science at Drexel University, authored a recent paper that suggests the coal industry must have known quite a bit, given how prominently it positioned itself in the climate denial movement.

Brulle researched 12 major groups and coalitions that argued against mandatory regulation of carbon dioxide from 1989 to 2015 — which he calls the “climate change countermovement.” That countermovement included 2,000 different businesses, political or social groups, as well as other organizations, but Brulle found that 179 core organizations belonged to multiple coalitions. Coal companies and predominantly coal-burning utilities were the most prevalent. He describes oil and gas companies as “more of a marginal player” by comparison.

“The coal mining industry — the utilities that were burning it for electricity, along with the railroads who were hauling it — and manufacturing industries like steel were the first corporate forces to become climate deniers and try to block action on climate policy,” said Kert Davies, founder and director of the Climate Investigations Center. “They fought the hardest because they had the biggest existential threat.”

Where do we go from here?

In the aftermath of the 1973 oil embargo, Exxon and other oil giants leased large parcels of land for coal mining with the goal of manufacturing synthetic fuels and lowering U.S. dependence on the Middle East.

Some previously released documents show that Exxon’s scientists began advising that the world phase out coal as a fuel as early as 1979. In one scenario, the Exxon scientists concluded that non-fossil fuels would need to be substituted for coal beginning in the 1990s to keep carbon dioxide levels below atmospheric concentrations of 440 parts per million. In 1999, Exxon merged with Mobil, and by 2002, ExxonMobil had dumped its coal assets.

Meanwhile, the coal industry tried to reinvent itself with the concept of “clean coal.” This as-yet-undelivered promise that carbon capture and other technological advances could lower coal’s environmental impact has been around for decades but resurged in the early 2000s as regulations seemed imminent.

The biggest proponent of this idea was the American Coalition for Clean Coal Electricity, a coal front group that spent $35 million on public relations campaigns in 2008 alone, seeking to influence the election. A year later, ACCCE was caught sending Congress fraudulent letters opposing federal climate legislation and pretending to be from veterans, women’s, and civil rights groups. The incident led many members to leave the organization, but Peabody remains a member to this day.

“Its whole mission was to stop climate regulations but pretend that they were in favor of clean coal, which, of course, doesn’t exist,” said Davies.

Peabody Energy filed for bankruptcy protection in 2016, the same year carbon dioxide levels hit 400 parts per million. Eight other coal companies have filed for bankruptcy this year. Even as the Trump administration has promised a coal resurgence and rolled back Obama-era regulations, the industry’s profitability continues to experience a downward slide. If the slogan “Coal Knew” ever does take off, it’s unclear who’ll be left to sue.

This story was originally published by Grist with the headline Exxon knew — and so did coal on Nov 29, 2019.


          

What Is The Most Exciting - Non iTunes - Option For Podcast Discovery? The Podcast Report Episode #6

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We've been talking about Podcast discover since day 1. There has always been this dream that if we build it, they will in fact come. What is the most exciting - non iTunes - option for Podcast discovery?


          

HomePWN y ataques de Replay BLE: Una demo en BlackHat Europe 2019 (Parte 2 de 2)

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En la primera parte de este artículo vimos cuál era la demo que queríamos realizar para lograr capturar las tramas de apertura de un SmartLock enviadas por BLE para poder hacer un ataque de Replay o de reutilización de paquetes. Este tipo de ataques se aprovechan de que son mensajes estáticos que no caducan y pueden utilizarse de forma repetida.

Figura 9: HomePWN y ataques de Replay BLE: Una demo en BlackHat Europe 2019
(Parte 2 de 2)

En la primera parte vimos cómo era la trama que se enviaba al SmartLock por BLE cuando la capturamos usando la herramienta BTLEJack, que nos permite acceder a las tramas de red que se envían por medio del protocolo BlueTooth Low Energy. Ahora vamos a ver la demo completa.

HomePWN BLE Replay Attack

En este apartado vamos a ver la demo paso a paso. Lo primero es tener HomePwn corriendo. Vamos a hacer uso de 3 módulos:
• Discovery/ble 
• Ble/read-characteristics 
• Ble/write-characteristics
Hay otro módulo que puede ser de gran utilidad en un momento determinado y es el de capture/bluetooth-scapy y capture/bluetooth-tcpdump. Estos módulos permiten capturar el tráfico bluetooth del equipo donde se ejecuta HomePwn.

Figura 10: Módulo discovery/ble en HomePWN

Con el módulo de discovery/ble podemos hacer el descubrimiento de dispositivos BLE con cierta información alrededor. Información como:
• Si es conectable el dispositivo. 
• El tipo de dirección (random, public...) 
• El manufacturer. 
• La bmac o dirección Bluetooth. 
• La intensidad de señal. Distancia al dispositivo.
Una vez ejecutamos el módulo y se realiza la búsqueda podemos obtener el listado de dispositivo con las características que se han encontrado. Dependiendo del entorno y del valor del rssi que configuremos podemos obtener un gran listado de dispositivos. Esto hay que tenerlo en cuenta.

Figura 11: Listado de dispositivos descubiertos

La información de la bmac es importante ya que para poder conectarnos y leer las características del dispositivo debemos hacer uso de ella. Ahora, cargamos el módulo ble/read-characteristics. Este módulo proporciona la posibilidad de listar las características y las propiedades de éstas.

Como se puede ver en la imagen, haciendo uso de la bmac, se puede ejecutar el módulo. Si conociéramos el UUID de alguna característica, podríamos acertar más fácilmente con el objetivo. El atributo type debe coincidir con el atributo AddrType del módulo anterior.

Figura 12: Módulo ble/read-characteristics

El módulo conecta y obtiene el listado de características y handles asociados. Esto es fundamental para el ataque de replay, ya que debemos conocer dónde se puede escribir, dónde se lee, dónde se puede subscribir al dispositivo, etcétera.

Figura 13: Información de características de un dispositivo descubierto por BLE

Si nos fijamos en la última característica, vemos que es de escritura sin respuesta, esto quiere decir que el comando es enviado a la característica, pero no se llevará a cabo ninguna respuesta. Si observamos el UUID de la captura de Wireshark obtenida con BTLEJack en la primera parte de este artículo podemos ver justamente que coincide. Parece que hemos encontrado la característica utilizada por la aplicación para poder escribir el código y abrir el SmartLock.

Figura 14: Módulo de ble/write-characteristic

El módulo ble/write-characteristic nos permite podemos escribir la información, previa conexión. En este caso, se configura la bmac, el UUID que hemos obtenido en el módulo anterior, se configura el comando que se quiere enviar a través del atributo data y e se proporciona el tipo de encode. Para este caso tenemos dos tipos de encode: HEX o ASCII.

La demo en vídeo

A continuación, os dejamos un vídeo de la demo completa para que podáis verla en ejecución. El ataque de Replay es llevado a cabo gracias al uso de HomePwn. El mundo del BLE tiene muchas posibilidades y esperamos ir añadiendo funcionalidades en el futuro.

Figura 15: Demo de BLE Replay Attack con HomePWN para abrir un SmartLock

Esperamos que os resulte de interés una de las demos que trataremos en BlackHat Arsenal 2019 y si estáis por ahí no dudéis en pasaros. Además, el próximo viernes estaré en Cybercamp 2019 con un taller de BLE y una charla sobre ATT&CK y alguna sorpresa. Tenemos una semana intensa como se puede ver. Esperemos estar mucho tiempo al pie del cañon en el equipo de Ideas Locas.

Saludos,

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- HomePwn y ataques de Replay BLE: Una demo en BlackHat Europe 2019 (1 de 2)
- HomePwn y ataques de Replay BLE: Una demo en BlackHat Europe 2019 (2 de 2)
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Autor: Pablo González Pérez (@pablogonzalezpe), escritor de los libros "Metasploit para Pentesters", "Hacking con Metasploit: Advanced Pentesting" "Hacking Windows", "Ethical Hacking", "Got Root" y “Pentesting con Powershell”, Microsoft MVP en Seguridad y Security Researcher en el equipo de "Ideas Locas" de la unidad CDO de Telefónica.

          

Introducing Biology's newest faculty

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Newsletter issue:
People:
Neda Bagheri
Alejandro Rico-Guevara
Kristiina Hurme
Jeff Rasmussen
Adam Steinbrenner
Julie Theriot

Welcome to UW Biology's newest faculty members! These renowned scholars and researchers come from all across the country and have added tremendous expertise to the UW Biology community. A special thank you to the Washington Research Foundation, Jodi Green, Mike Halperin, Walt Halperin, Margaret Hall, and the late Ben Hall for making these hires possible!

Here is a brief look at the newest members of the UW Biology community:

Neda Bagheri
Assistant Professor
WRF Distinguished Investigator

Education:

PhD in Electrical Engineering from UC Santa Barbara
Postdoc in Biological Engineering from MIT

Expertise:

My lab—aptly named the MOdeling DYnamics of Living Systems (MODYLS) Lab—employs tools across engineering and applied math to help explain unintuitive biological observations and to gain fundamental insight. My primary areas of expertise include systems biology, dynamical systems, and control theory. An exciting application of our research that integrates skills across these domains involves predicting emergent dynamics within and among cell populations using multi-scale, multi-class computational models.  

Most fascinating research discovery:

Understanding how the context of the microenvironment shapes cell decisions.

Accolades:

NSF CAREER Award, National Science Foundation Directorate for Engineering

Distinguished Speaker for the Accelerated Discovery Forum at IBM Research-Almaden and Keynote Speaker at multiple international conferences

Mindlin Foundation Public Lecture at University of Washington

Cornew Innovation Award, Northwestern University Chemistry of Life Processes

Extracurricular:

  1. If not a Biology professor, I would be: Hiking above tree line.​
  2. Favorite hobbies:​ I love being outside—hiking, cycling, climbing—and playing ultimate frisbee.​
  3. What is one thing you will never do again? Learn how to drive a motorcycle through trial and error. (Take a class!)
  4. What motivates you to work hard? I love to enable, promote, and empower the next generation of citizens and thought leaders.
  5. If you could choose to do anything for a day, what would it be? Paraglide across the alps (with proper instruction and safety, of course)

Kristiina Hurme
Lecturer, full-time

Education:

B.A. Princeton University
Ph.D. University of Connecticut

Expertise:

I’m a Behavioral Ecologist that has studied parental care, territoriality, male-male combat, vocal communication, mating and courtship in frogs, birds, and fish throughout the Neotropics. In zoos I designed enrichment for monkeys and frogs, and used positive reinforcement to train monkeys and sea lions, skills that I am now using to study wild hummingbirds!

Most fascinating research discovery:

For my dissertation, I studied maternal care in a neotropical frog, Leptodactylus insularum, in Panama. These large frog mommas often care for schools of 1000s of tadpoles in temporary ponds. I found that they reached metamorphosis surprisingly quickly, growing from egg to juvenile froglet in about two weeks! In order to grow and develop so fast, these tadpoles were constantly active and foraging. This activity attracted a lot of attention from predators, such as fishing spiders and herons, and I found that the only schools that survived to metamorphosis had a mother guarding them. These courageous moms not only fought off predators (even my hand!), but also communicated with the schools, guiding them to safe foraging areas. Some males have large and muscular arms with thumb spines (intrasexually selected weapons), and the only males I observed breeding were huge and covered in battle scars.

Accolades:

I received Honorable Mention for the Graduate Student Teaching Excellence Award at the Ecology and Evolutionary Biology Department, University of Connecticut.

Our recent paper on Intrasexually Selected Weapons was selected as the cover of the latest volume (five issues) of Biological Reviews: onlinelibrary.wiley.com/loi/1469185x/year/2019

Extracurricular:

  1. If not a Biology professor, I would bean artist, a zookeeper, a scientific illustrator, a wildlife film maker – something that allows me to observe and appreciate the natural world and share it with others.
  2. What is your favorite book? “My Family and Other Animals”, by Gerald Durrell. Growing up as a young naturalist on a Greek Island – what a dream!
  3. What is your proudest accomplishment? Working as a team with my husband Alejandro. In life, raising our daughters, Sierra and Aurora. In research, training wild hummingbirds to voluntarily drink from intimidating experimental setups, resulting in a stress-free way to measure behavior and physiology. Check out the PBS nature documentary “Super Hummingbirds” for examples!
  4. What are your hobbies? Fencing, anything related to horses, nature photography, exploring nature with two little kids.
  5. What makes you happy? Seeing the “aha” moment in students, sharing a love and enthusiasm for biology and observation of the natural world, showing students cool and surprising animal behaviors, often with the help of David Attenborough!
  6. Why did you choose to work at UW Biology? I fell in love with the department because of how everyone prioritizes excellence in teaching biology and collaborates on assessing how students learn! I am so excited to be in a place where I will be supported and encouraged!

Jeff Rasmussen
Assistant Professor
WRF Distinguished Investigator

Education:

2011, Ph.D., Molecular and Cellular Biology, University of Washington, Seattle, WA
2002, Sc.B., Computational Biology, Brown University, Providence, RI

Expertise:

I am broadly interested in cell and developmental biology, in particular how cells adopt and maintain specific shapes. My lab uses zebrafish to gain molecular and cellular insights into the development and repair of somatosensory neurons, which are some of the largest and most complex cells in the body. Somatosensory neurons build enormous and elaborate peripheral axons that innervate the skin to detect pain and touch. Our current focus is on understanding interactions between these somatosensory axon endings and the various specialized cell types they encounter in the skin.

Most fascinating research discovery:

As a graduate student, I discovered that cells within the worm embryo could fuse with themselves to form tiny, single-cell tubes in the shape of a donut.

Accolades:

2018, Hilde Mangold Postdoctoral Presentation Award, Society for Developmental Biology (SDB) 77th Annual Meeting, Portland, OR

2013—2016, Postdoctoral Fellow, Jane Coffin Childs Memorial Fund

2007—2010, Predoctoral Trainee, NIH Training Grant in Developmental Biology, University of Washington

Extracurricular:

  1. If not a Biology professor, I would be: pursuing something artistic.
  2. What are your hobbies? Playing soccer, running, and eating vegetarian food.
  3. What makes you happy? A sunny day in Seattle.
  4. Why did you choose to work at UW Biology? For the opportunity to work with fantastic colleagues and great students.
  5. What is your morning routine? I make breakfast for my kids, give my daughter a big hug when I drop her off at preschool, run to campus and enjoy a big mug of green tea while thinking about science.
  6. If you could choose to do anything for a day, what would it be? You mean I get to choose my superpower? Teleportation! That way I could visit the Wonders of the World without any lines.

Alejandro Rico-Guevara
Assistant Professor
Walt Halperin Endowed Professor
WRF Distinguished Investigator

Education:

Biologist - Universidad Nacional de Colombia
PhD- University of Connecticut, Miller Fellow- UC Berkeley.

Expertise:

I perform theoretical and empirical research on Behavioral Ecophysics, which I define as the study of organismal mechanisms (e.g. physiology, biomechanics) and their explicit links to biotic and abiotic interactions. My recent discoveries on nectar collection and intrasexually selected weapons revive questions on how animals balance caloric gain and expenditure, and on foraging theory in light of both exploitative and interference competition. I have focused on the most specialized vertebrate pollinators, hummingbirds, and working on such a data-rich mutualistic system opens the door to quantitative (e.g. energetics) and comparative (e.g. other nectarivores) assessments of trade-offs between energy optimality and fighting proficiency in nature.

Most fascinating research discovery:

How hummingbirds actually drink, associated adaptations in their feeding apparatus, and deviations under opposing selective pressures (e.g. bills as weapons).

Accolades (2-4 maximum):

Frank A. Pitelka Award for Excellence in Research, International Society for Behavioral Ecology. behavecol.com/awards-1

Kimberly G. Smith Outstanding Student Paper Award, Organization for Tropical Studies, 7th Annual Competition. tropicalstudies.org/research

Best Doctoral Dissertation, Greg and Mona Anderson Award, Department of Ecology and Evolutionary Biology, University of Connecticut. eeb.uconn.edu

Best Oral Presentation Award, IV Colombian Zoology Congress (selected among 2000 presentations). vccz.aczcolombia.org

Extracurricular:

  1. If not a Biology professor, I would be: Most likely I would have looked for an occupation that would have kept me in touch with nature and being outdoors: a farmer, a birdwatching guide, a park ranger, a mountain rescue responder, a scuba instructor, something like that. To some degree, I’ve tried all of the above at different stages of my life!
  2. What makes you happy? Being with my loved ones, but it doesn’t really matter what I’m doing (from hanging out in my grandma’s house for lunch, to family fencing being beaten by my in-laws!). Especially treasuring day-to-day unrepeatable moments with my wife, Kristiina, and watching our little fledglings, Sierra Annaleema and Aurora Delta, grow.
  3. Why did you choose to work at UW Biology? Because of the supportive and collaborative spirit, world-class academic excellence, its integrative approaches, the strong emphasis both in research and teaching, its interdisciplinarity, and the tight links with the Burke Museum, highlighting the importance of science communication, among many other reasons!
  4. What is your favorite childhood memory? Going on weekend trips and vacations with my parents and sisters, regardless if it was to stop on the side of the road, or going to the closest river to cook on a campfire, and all the way to when we were able to “meet the sea”. My dad is a naturalist at heart, and we have had tons of fun exploring nature together. I’m a biologist because of him!​
  5. What motivates you to work hard? A deep desire to understand the mysteries of life. Whether that means doing careful lab experiments and developing home-made devices, or spending a lot of time in the field chasing elusive behaviors; the motivation is always to go beyond the limits of our knowledge. And now supporting others to pursue similar dreams!

Adam Steinbrenner
Assistant Professor
WRF Distinguished Investigator

Education:

BS Tufts University
PhD UC Berkeley

Expertise:

My lab studies the plant immune system.  Plants defend themselves from pests and pathogens (bacteria, fungi, herbivores, etc) by detecting molecular signatures of attackers.  We are interested in receptor proteins that recognize different types of pests and how these receptors evolve in both nature and agriculture.  We hope that better understanding plant defenses will inform and inspire strategies to reduce pesticide use and develop sustainable pest control.

Most fascinating research discovery:

In my most recent position at UC San Diego, we identified a plant immune receptor that detects peptides in larval oral secretions (i.e. caterpillar spit).  Interestingly, this receptor gene is unique to the genomes of certain legume crop species such as bean and black-eyed pea, suggesting they have a unique defense strategy against attacking insects.

Accolades:

HHMI Postdoctoral Fellow 2016-2019

NSF Graduate Research Fellow 2010-2015.

Extracurricular:

  1. What is your favorite book? Team of Rivals by Doris Kearns Goodwin, Master of the Senate by Robert Caro, Anna Karenina by Leo Tolstoy
  2. What are your hobbies? Running, Hiking, Fermentation + gardening projects at home
  3. Why did you choose to work at UW Biology? UW Biology has an incredibly integrative atmosphere that fits my research style.  I try not to stay too focused on a single topic or technique, but look for links across molecular biology, genomics, and evolution/ecology.  I’m looking forward to growing my lab’s connections in the department and across campus.
  4. What is your favorite childhood memory? My mother was a landscape designer and I grew up visiting gardens and arboretums around Philadelphia.  I especially loved identifying trees and observing them across the seasons.  It is fun to see paperbark maples around Seattle – one of my old favorites from the east coast!
  5. What was your favorite subject in school? History and Political Science.  It is fascinating to learn about other societies, institutions, norms.
  6. What’s the most interesting thing you can see out of your office or kitchen window? The Space Needle view from 5th floor LSB is fantastic​
  7. What motivates you to work hard? Beyond the day to day joy of experiments, it is motivating to know that basic findings in biology can eventually translate into amazing applied breakthroughs.  In a recent example, the set of tools for CRISPR-mediated genome editing originated from observations and experiments in basic microbiology / RNA biochemistry.  The previous generation of genome editing molecules, TALENs, were originally identified from bacterial pathogens of plants that used similar proteins to manipulate their hosts.

Julie Theriot
Professor
Benjamin D. Hall Endowed Chair in Basic Life Sciences

Education: 

BS Biology and Physics, Massachusetts Institute of Technology
PhD Cell Biology, University of California, San Francisco

Expertise

The research of our group explores the mechanics and dynamics of cell self-organization and movement in a variety of cells ranging from bacteria to fish skin cells.  Our current work focuses on three areas:  1) the actin-based motility of intracellular bacterial pathogens such as Listeria monocytogenes, 2) the whole-cell crawling of epithelial cells and leukocytes, and related processes such as phagocytosis in macrophages, and 3) the dynamics of cellular organization in bacteria and diatoms.  A strength of our work is its highly interdisciplinary nature, bridging cell biology, microbiology, and biophysics.  By studying diverse questions in diverse biological systems, using both bottom-up approaches (biochemical reconstitution, single-molecule force measurements, mathematical modeling) and top-down approaches (genetic and pharmacological perturbations, quantitative video-based analysis of cell movement, shape, and mechanical coupling), we aim to develop a broad conceptual understanding of the organizational rules that give rise to large-scale cell structure and coordinated movement. 


          

Brewing up Biology lessons

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Newsletter issue:
Fields of interest:
People:
Alexander Paredez

Walk into one of Biology’s teaching labs next quarter and you might find a group of students hovering over a beer kettle. A strange sight for the casual observer, but an all too familiar experience for Biology students taking BIOL/BIOC 495: Fermentation Biology. Led by Alex Paredez (UW Biology) and Justin Kollman (Biochemistry), BIOL 495 introduces students to beer brewing and wine making. Since its inception last year, Fermentation Biology has turned into one of Biology’s most popular courses – filling up instantaneously within minutes of registration.

Alex first started brewing beer as an undergraduate at UC San Diego. When the UCSD Craft Center offered a brewing class, he signed up and made his first foray into science. Paredez remarks, “the truth is, my initial interest in research was motivated by wanting to learn how to culture beer yeast.” And so, armed with his home-brewed beer, he offered a six-pack to his genetics professor, who gave him his first research position. Though Alex started off interested in beer brewing, his interests soon expanded to studying the intestinal parasite Giardia lamblia. The Paredez lab studies how Giardia’s cytoskeleton mediates parasite attachment to the host intestine and the signaling pathways that regulate parasite transmission. The unifying goal is to identify therapeutic strategies to clear infection. Never forget: “In wine there is wisdom, in beer there is freedom, in water there is Giardia.”

Even though Alex is now a UW Biology Professor, he hasn’t forgotten about his undergraduate days. He still brews beer on occasion and runs a wine making co-op where people can chip in and assist with turning two tons of grapes into ~1,200 bottles of wine. So, when Ben Wiggins suggested he start a beer brewing class, Alex was more than excited to get started. But not without first recruiting a colleague and fellow brewer, Justin Kollman from UW Biochemistry, to help out.

In BIOL 495, students start by learning the history of brewing. In fact, it was Louis Pasteur’s initial interest in fermentation – determining that fermentation was caused by living microorganisms – that eventually led to the discovery of germ theory. Using what he learned from his fermentation experiments, he discovered new species of bacteria and made advances in vaccination techniques.

Students then jump quickly into the biology behind the process. Beer brewing involves everything from microbes to metabolic biochemistry, so students learn a wide breadth of topics including:

  • Microscopy, solution-making, cell counting, calculations, and other basic lab techniques
  • The enzymatic process that turns starch into sugar for fermentation
  • How the fermentation process leads to the intriguing flavors found in beer and wine
  • The effect of different yeasts on the same base brew
  • The ecology of wine fermentation – studying the community composition of microbes and how it changes with different inputs and environments

While most of the class is in the lab, the final project is brewed in the Life Sciences Building, where students can enjoy their hard work and share their homemade brews with others.

Alex and Justin also expose students to the industry side of brewing. Last year, students visited Magnuson Brewery to see how professionals handle fermentation and do business. For this year’s course, Alex and Justin hope to bring in more guest speakers so students can learn from industry experts. They are also planning to take the course a step further by teaching food fermentation.

Overall, both Alex and Justin say the most valuable thing about the course is the application of basic biological topics. The course gives students a reason to care; they’re not just learning the processes, but are learning why they’re important as well. Justin teaches introductory biochemistry, but loves teaching this course because it makes the practical applications of biochemistry clear. And above all, beer brewing is fun! BIOL 495 maintained 100 percent attendance last year, and many students say it was the best course they’ve taken at the University of Washington.

When registration for BIOL 495 opens for Winter 2020, you can be sure the seats will be snapped up quickly. Learning Biology is always fun - made even more so by passionate faculty members and a few hard-earned brews.


          

Infographic Of The Day: The Race To Invest In The Space Economy

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Today's infographic highlights the exciting journey humans have taken into outer space and the economic boom across industries as a result of this quest for discovery.

Read more ...


          

GE Additive on taking additive manufacturing from discovery to industrialisation

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GE Additive's Chief Technology Officer Christine Furstoss talks to TCT about new products and how the company is making additive manufacturing more repeatable.
          

Ulf Fernström (1915-1985) and his Contributions to the Development of Artificial Disc Replacements.

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INTRODUCTION: Artificial disc replacements, which serve the function of separating vertebrae to allow for proper spinal alignment, can help treat debilitating low back pain in patients who have failed other conservative methods of treatment. A Swedish surgeon, Ulf Fernström, was the pioneer of artificial disc replacement, and his contribution in the form of Fernström balls dramatically altered spinal surgery and technique by showing the proper technique and implant that should be used for areas requiring motion in many planes.

HISTORY OF THE ARTIFICIAL DISC: Ulf Fernström created his artificial disc inspired by the movement of the hip and knee joints. His implants attempted to restore disc spacing and articulation in patients who had failed conservative measures of treatment. Fernström balls were the first implants of their kind and represent the first attempt at artificial disc replacement. However, many surgeons and researchers questioned Fernström balls, claiming that their lack of elastic properties could damage patients.

CONCLUSIONS: Of the wide range of implants on the market for the intervertebral disc space, all designs and applications of products stem from the initial discovery made by Fernström, thus making him a pioneer in disc replacement.


          

Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk-A re-analysis of eight GWASs.

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PURPOSE: mRNA degradation is an important regulatory step for controlling gene expression and cell functions. Genetic abnormalities involved in mRNA degradation genes were found to be associated with cancer risks. Therefore, we systematically investigated the roles of genetic variants in the general mRNA degradation pathway in lung cancer risk.

EXPERIMENTAL DESIGN: Meta-analyses were conducted using summary data from six lung cancer genome-wide association studies (GWASs) from the Transdisciplinary Research in Cancer of the Lung and additional two GWASs from Harvard University and deCODE in the International Lung Cancer Consortium. Expression quantitative trait loci analysis (eQTL) was used for in silico functional validation of the identified significant susceptibility loci.

RESULTS: This pathway-based analysis included 6816 single nucleotide polymorphisms (SNP) in 68 genes in 14 463 lung cancer cases and 44 188 controls. In the single-locus analysis, we found that 20 SNPs were associated with lung cancer risk with a false discovery rate threshold of

CONCLUSION: The CNOT6 rs2453176 SNP may be a new functional susceptible locus for lung cancer risk. © 2016 Wiley Periodicals, Inc.


          

Tutor - FSC Slapton

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Field Studies Council (FSC), Slapton, Nr Kingsbridge, Devon, £17,260 - £19,697 pa. Imagine a job where you can use your environmental knowledge every day, helping to shape the minds of the new generation; a job where you work as part of a team in the great outdoors, inspiring others and developing passions for the future. Teaching with FSC gives you a role with both challenge and opportunity, and a chance to start young people on a journey of discovery that can last a lifetime. FSC are looking for people with a curiosity for the world around u...
          

Farm Discovery Coordinator - N Hampshire (Self employed)

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The Country Trust, Home based (Basingstoke/Reading/Rushmoor area), £120/day. Please note we do not accept CVs without a completed application form Location: Homebased (Basingstoke/Reading/Rushmoor Area) Working particularly with schools in Basingstoke, Reading, Newbury, Rushmoor and potentially Crawley, and farmer hosts in the surrounding area. Host farms ideally to be within an hour’s travel. Reports to: Farm Discovery Manager Main purpose of the role: To organise and deliver an agreed number of visits for the Country ...
          

Area Programme Manager

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Groundwork South, Hastings, East Sussex, £36,000 - £40,000 pa. Role: Area Programme Manager Ref: SS09 Salary: £36,000 - £40,000 Hours: 37.5 hours per week Contract Type: Permanent Location: Hastings County Council Offices, Discovery Centre, Combe Valley Countryside Park Operational Area: East & West Sussex with potential expansion into Kent ROLE DESCRIPTION: At community charity, Groundwork South, we are changing places, changing lives across the South of Engla...
          

Materials Discovery

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Materials Discovery

Ytterligare sökbara ISSN (elektroniska): 2352-9245

Tidskrift

Titlar
  • Materials Discovery
Ytterligare sökbara ISSN (elektroniska)2352-9245
Scopus-ID21100782433

          

Land Rover Discovery Sport 2016 Wiring Diagram

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Land Rover Discovery Sport 2016 Wiring Diagram
          

Chet Raymo, “The Mystery of Life? I Don't Know”

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“The Mystery of Life? I Don't Know”
by Chet Raymo

“Albert Einstein said, "Theories should be as simple as possible, but no simpler." At first glance, this may sound like a Zen koan, or a paradox. In fact, it is a profound statement that says more than volumes of philosophy. But first, a bit of background.

From the dawn of time, people have resisted saying "I don't know." They looked instead for explanations in tribal tradition, sacred books, or the supposed wisdom of shamans, priests and prophets. The most common cover-up for ignorance is to invoke divinity. A storm that devastates a village is "an act of God." A child taken by disease at a young age is divine punishment for a parent's sin. And so on.

Superstitions too have their origin as a cover for ignorance. I lost my wallet because a black cat crossed my path. My lover left me because Venus was in the wrong house of the zodiac. I won at the roulette table because I was holding my lucky rabbit's foot. In every case a reluctance to say, "I don't know." No admission that the cause of an event might be unknown or unknowable. Traditionally, people have divided explanations into true and false. In general, truth is what we believe. Falsehood is what everyone else believes, if different. Einstein's remark suggests another attitude towards knowledge.

On the one hand, we have reliable theories, characterized by the simplicity with which they explain experience. Not absolute truths, but provisional truths that work well for the time being and are open to revision. For example, Newton's theory of gravity qualifies as reliable knowledge because of the way a few simple equations explain everything from the motion of planets, to the fall of an apple, to the flow of the tides. With Newton's equations we can predict the return of a comet- Halley's Comet, say- to the day, hour, second, hundreds of years in advance. That's reliable knowledge.

The theory of evolution by natural selection explains with almost self-evident simplicity the diversity and interrelatedness of life on Earth as revealed in the fossil record and in the genes. That's reliable knowledge. That's knowledge as simple as we can make it. Beyond that, according to Einstein, we must be humble enough to say "I don't know." Those three little words, "I don't know," are completely modern. They are the essence of the scientific way of knowing, and they set the person of scientific temperament apart from every other people who have gone before- and from most people who are alive today.

Beneath reliable knowledge Einstein draws a line. Don't suppose we know what we don't know, he suggests. Don't make up fictions- gods, spirits, superstitions, the influence of the stars, lucky charms- to explain things for which we have as yet no reliable explanation.

As simple as possible, but not simpler. The physician/essayist Lewis Thomas wrote: "The greatest of all the accomplishments of 20th-century science has been the discovery of human ignorance." He was talking about the recognition that there is an entire universe below Einstein's bottom line about which we know nothing, and about which we should be willing to admit that we know nothing.

Those three little words- "I don't know"- are used far too infrequently by teachers, politicians, religious leaders, even philosophers. With the presumption of knowledge where no reliable knowledge exists goes righteousness. Righteousness breeds pogroms, jihads and crusades. Righteousness flies airplanes into skyscrapers and holds children hostage in schools. Righteousness presumes to forcibly impose on others what we think they want or need.

If science has given one great gift to the world- greater than the wonders of technology, greater than modern medicine, greater than flights to the moon and planets- it has given us permission to say "I don't know." How did life evolve from non-life? I don't know. What is consciousness? I don't know. What started the big bang? I don't know. Why did my father die at a relatively young age of cancer? I don't know. Why do bad things happen to good people? I don't know.

As simple as possible, but no simpler. Ironically, it is when we give up thinking we know it all that we begin to acquire reliable knowledge. When we think we know everything, thinking stops.”

          

“Optical Illusions Show How We See”

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 “Optical Illusions Show How We See”
by Beau Lotto

"Editors note: R. Beau Lotto is founder of Lottolab, a hybrid art studio and science lab based in London, England. Lotto gave a popular talk at the TED Global conference in Oxford, England, in July 2009. In the video, Lotto shares some surprising optical illusions - and explains the deep brain science behind them. Here, Lotto explains why our eyes try to fool our brains."

"Seeing lightness and color are the simplest sensations the brain has. And yet even at this most basic level we never see the light that falls onto our eyes (called the retinal image) or even the real-world source of that image. Rather, neuroscience research tells us that we only ever see what proved useful to see in the past. Illusions are a simple but powerful example of this point. Like all our perceptions, we see illusions because the brain evolved not to see the retinal image, but to resolve the inherent "meaninglessness" of that image by continually redefining normality, a normality that is necessarily grounded in relationships, history and ecology.

Which is why we innately find regularities in information and reflexively imbue those regularities with value. But it is the value, not the information itself we see. So, tomorrow morning when you open your eyes and look "out into" the world, don't be fooled. You're in fact looking in. You're not seeing the world; you're seeing a world... an internal map of value-relations derived from interactions within a particular, narrow context.

Another essential point about illusions implied in my TED talk is that they reveal our amazing capacity to entertain mutually exclusive internal realities simultaneously. For instance, while looking at one of my color illusions (say the multicolored cube) you're aware of one reality: that two tiles look very different, while simultaneously being aware of an opposite reality: that the two tiles are in fact physically the same. This capacity to be an observer of yourself is phenomenal and possibly unique to humans. Indeed, to literally "see yourself see" is in my view the principal act of consciousness, which has the power to transform one's view of the world and of oneself.

The importance of the above observations stemming from my own work and that of others transcend neuroscience. They show us in an explicit (and I hope engaging) way that our senses are not "fragile," as many would have you believe. They show us instead that we are not outside observers of nature defined in isolation. We are instead indivisible from nature, defined by the trial and error process of interaction, a process in which we can choose to become active agents (but too often choose not to).

Understanding this point is I believe critical to personal and social well-being, since the typical barrier to a deeper insight into oneself and others is the overriding, but necessarily false impression that what "I" see, what "I" hear and what "I" know is the world as it really is. But, by "seeing yourself see," in other words by actively exploring how your thoughts, feelings, beliefs and even the colors you see reflect your physical, social and cultural ecology, only then is it possible to understand the source of coherence and conflict within and between individuals. Put another way, only by accepting my own humanity can I accept the humanity of others. "Seeing myself see" creates the opportunity for this acceptance. Illusions, then, were not the point of my talk, but simply a tool for encouraging this process.

Resolving uncertainty is essential to our survival. Hence our fear of ambiguous situations is palpable- e.g., the inability to resolve sensory conflict between the eyes and ears can result in nausea (like seasickness). And yet it is only by embracing the unknown within education, science, art and most importantly within our own private lives that we will find new routes to more enlightened ways of seeing and being.

Thus, courage not confidence is at the heart of this process of actively redefining normality, which is the route to compassion and creativity. Encouraging this process by celebrating uncertainty is the raison d'etre of my work, from the science of human and bee perception, to the art of translating images into music, to the design of a glass windmill for primary schools, to the creation of the "My School" educational program (a framework for teaching and architecture that directly supports creativity, community choice and compassion), even to giving a talk at TED. By providing relevant, tangible and accessible frameworks for others to take part in the process of discovery, I hope - in a very modest way - that my work will help foster a more empathetic view of nature and human nature."

          

"Holidays aren’t just our history. They’re our present. They show us the way forward."

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In Front Page Magazine, Daniel Greenfield wrote,
Thanksgiving teaches us two values that lefties hate: gratitude to a higher power and coexistence.

...Days of thanksgiving were not unique in American history. But Thanksgiving as a paradigm of man’s relationship with G-d, and man’s relationship with man, is part of American exceptionalism. It’s how English, Scottish, French, and Dutch settlers were able to come together. And how waves of German, Irish, Jewish, Swedish, and Italian immigrants joined them to make the United States of America.

It’s why, despite the weight of history, African-Americans, Mexicans, and American Indians could all meet around a common national table in thankfulness and fellowship even in a divided nation.

...The real lesson of Thanksgiving is not that history isn’t complex, or that oppression doesn’t exist, but that oppression is not the most powerful force in human history. Fellowship and gratitude are. Politeness and civility are not a white supremacist conspiracy. They are the ways that we live together.

Assuming that we want to live together.

Thanksgiving doesn’t mean that we don’t have fundamental differences. The pilgrims and the Indians certainly did. They don’t mean that we have never fought and will never fight again. Only that we will not fight in this moment, that we will appreciate our common humanity, and the higher power that blesses us with prosperity and peace. If we can’t do that even for a moment, then we can’t coexist.

...Columbus Day has become a casualty in many parts of the country. Thanksgiving is next. And then the Fourth of July. Each of those days plays a vital role, not only in the nation’s history, but in its present. They’re part of an ongoing journey, of discovery, coexistence, and independence that has not ended.

Holidays aren’t just our history. They’re our present. They show us the way forward.

...Thanksgiving is a weapon that shatters the politics, history, and economic theorems of the Left. That weapon is the transcendence of gratitude. The politics of radicalism are fueled by outrage. Nothing is ever forgotten or forgiven. There is never a moment’s peace. Not even at the dinner table.

But Thanksgiving reminds us that we don’t have to be prisoners of the past. That our conflicts, past and present, personal and national, can be set aside if we choose faith and love, even for a moment.

...Thanksgiving liberates us from that prison, as it liberated the ancestors of our nation. Americans are not the prisoners of history. We make our own history. We transcend our past and build our future.

That is the power of Thanksgiving. It frightens the Left. And it should.

Thanksgiving, from its earliest days, had the power to unite a nation. The greatest weapon of the radicals is division. They amplify the divisions of family and nation, breaking us apart and driving the wedges deeper. But the true power of Thanksgiving can defeat them and reunite a nation.
Read more here.
          

Moctezuma II - Aztekernas domedagsprofet

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Den sista härskaren av det mäktiga Aztekriket. En krigsherre vars magkänsla vid mötet med de spanska conquistadorerna ledde Amerikas största civilisation rätt ner i avgrunden.

Vill du veta mer om Moctezuma II? Här är några av de böcker som legat till grund för avsnittet: Aztecs - An Interpretation av Inga Clendinnen  The Discovery and Conquest of Mexico av Bernal Diáz del Castillo The Aztec world av Elizabeth M. Brumfield & Gary M. Feinman                                                                                                                                Cortés och aztecernas underkuvande av Blacker, Irwin R.                                                                                    Cortés och Montezuma av Collis, Maurice Redaktionen för detta avsnitt består av: Cecilia Düringer - programledare och manus Adrian Boberg - manus och research Navid Bavey- scenuppläsare Samuel Lindberg -  ljuddesign och slutmix Tove Palén - producent Medverkar gör också Daniel Andersson docent i religionsvetenskap vid Göteborgs universitet.
          

‘For Sama,’ Renee Zellweger Win Big at British Independent Film Awards

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Syrian documentary “For Sama” was the big winner at the British Independent Film Awards on Sunday, taking home four awards for its sobering portrayal of how the ongoing war in Syria affects the women who live there.

“For Sama,” directed by Aleppo resident Waad al-Kateab with Edward Watts, follows al-Kateab through five years of her life as she gets married and gives birth to her daughter, Sama, all while the city crumbles around her. The film won BIFAs for Best British Independent Film, Best Director, Best Documentary, and Best Film Editing, adding to an awards list that includes The Golden Eye for Best Documentary at the 2019 Cannes Film Festival and Grand Jury Award for Best Documentary at the SXSW Film Festival.

Other winners include Best Actress Oscar contender Renee Zellweger, who won a BIFA for her performance as Judy Garland in the biopic “Judy.” The Best Actor award went to Josh O’Connor for his performance in the Harry Wootliff romance “Only You.”

Armando Iannucci’s “The Personal History of David Copperfield,” which premiered at TIFF and will be released in theaters in 2020, won for Best Screenplay and Best Supporting Actor for Hugh Laurie. Bong Joon-ho’s “Parasite,” which is seeing buzz build around it for a Best Picture Oscar nomination, won for Best International Independent Film

Read the full winners list below:

The Richard Harris Award for Outstanding Contribution by an Actor to British Film

Kristin Scott Thomas

Special Jury Prize

Amanda Nevill

Best British Independent Film

“For Sama”

Best Director

Waad Al-Kateab, Edward Watts (“For Sama”)

Best Screenplay

Armando Ianucci, Simon Blackwell (“The Personal History of David Copperfield”)

Best Documentary

“For Sama”

Best Actress

Renee Zellweger (“Judy”)

Best Actor

Josh O’Connor (“Only You”)

Best Supporting Actress

Ruthxjiah Bellenea (“The Last Tree”)

Best Supporting Actor

Hugh Laurie (“The Personal History of David Copperfield”)

Most Promising Newcomer

Sam Adewunmi (“The Last Tree”)

The Douglas Hickox Award (Debut Director)

Harry Wootliff (“Only You”)

Debut Screenwriter

Emma Jane Unsworth (“Animals”)

Breakthrough Producer

Kate Byers, Linn Waite (“Bait”)

The Raindance Discovery Award

“Children of the Snow Land”

Best Casting

Sarah Crowe (“The Personal History of David Copperfield”)

Best Cinematography

Benjamin Kracun (“Beats”)

Best Costume Design

Suzie Harman, Robert Worley (“The Personal History of David Copperfield”)

Best Editing

Chloe Lambourne, Simon McMahon (“For Sama”)

Best Effects

Howard Jones (“A Shaun the Sheep Movie: Farmageddon”)

Best Make-Up & Hair Design

Jeremy Woodhead (“Judy”)

Best Music

Jack Arnold (“Wild Rose”)

Best Production Design

Cristina Casali (“The Personal History of David Copperfield”)

Best Sound

David Bowtle-McMillan, Joakim Sundstrom, Robert Farr (“Beats”)

Best British Short Film

“Anna”

Best International Independent Film

“Parasite”

Related stories from TheWrap:

Graham Norton to Host 2020 BAFTA Film Awards

Jane Fonda Accepts BAFTA Award as She's Arrested

BAFTA Los Angeles Names Matthew Wiseman as New CEO


          

‘E.T. the Extra-Terrestrial': What Has the Cast Been Up to Since E.T. First Phoned Home? (Photos)

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“E.T. the Extra-Terrestrial” came back into our lives over Thanksgiving courtesy of a new holiday ad from Comcast’s cable and internet provider Xfinity.

In the spot, E.T. travels to Earth to reunite with a grown-up Elliott and his new family. Henry Thomas, the actor who originally played Elliott in the 1982 film, is now a married 40-something father of two.

It’s been more than 35 years since E.T. first came to Earth and change Elliot’s and his family’s life. Since E.T.’s back to check in on his old friend, but what have the actors been up to since E.T. phoned home?

Henry Thomas (Elliot)

Thomas has had a steady career since his breakout role as Elliot in Steven Spielberg’s 1982 hit. He worked with Martin Scorsese in “Gangs of New York,” and most recently played the young version of Hugh Crain on Netflix’s “Haunting of Hill House.”

Drew Barrymore (Gertie)

Barrymore of course rode her role as Elliot’s adorable little sister to super stardom and a storied career with iconic performances in films such as “Scream,” “Never Been Kissed” and “Whip It,” which she also directed. Barrymore has spent a lot of time recently producing, including an executive producer credit on the new “Charlie’s Angels.” Her Netflix show “The Santa Clarita Diet” wrapped up its final season in March 2019.

Robert MacNaughton (Michael)

MacNaughton continued to act throughout the 80s following “E.T.,” appearing in “I Am the Cheese” and the TV series “Vietnam War Story.” It was 27 years until he returned to the screen, with roles in “Frankenstein vs. the Mummy” and “Laugh Killer Laugh” in 2015.

Dee Wallace (Mary)

After playing the maternal figure in “E.T.,” Wallace went on to star in “Cujo” and a host of other films. She’s worked with Rob Zombie on a number of occasions. Wallace has also had guest appearances on TV shows such as “NCIS” and “You’re the Worst.” Wallace is still acting, recently appearing in Rob Zombie’s 2019 film “3 From Hell.”

Peter Coyote (Keys)

Coyote has since acted in such films as “Patch Adams,” “Erin Brockovich,” and “A Walk to Remember.” He’s had guest appearances on “Law and Order,” “NCIS,” and “Blue Bloods.” In 2020 he’s set to appear as Robert Mueller in the TV mini series “A Higher Loyalty” on CBS.

Related stories from TheWrap:

Apple Orders Follow Up to 'Band of Brothers' and 'The Pacific' From Tom Hanks and Steven Spielberg

Steven Spielberg and Alex Gibney's Docuseries 'Why We Hate' Gets Premiere Date From Discovery (Exclusive)

Steven Spielberg's 'West Side Story' Offers First Look at Ansel Elgort, Rachel Zegler and the Rival Gangs


          

1998 Discovery Motorhome Battery Wiring Diagram

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1998 Discovery Motorhome Battery Wiring Diagram
          

george james: Executive Director/Vice President Business Development EU - CRO - Ref.: CH181119DM

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Our global CRO client supports their customers in the discovery and development of future therapeutics. Through comprehensive discovery and technology platforms, peer-recognized scientific leadership and expertise in oncology, immunology, infectious disease, neurosciences, fibrosis, cardiovascular and metabolic disease, they work collaboratively to rapidly advance programs from target through to preclinical selection and beyond.


          

Researchers use machine learning tools to reveal how memories are coded in the brain | Mind & Brain - Science Daily

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NUS researchers have made a breakthrough in the field of cognitive computational neuroscience, by discovering a key aspect of how the brain encodes short-term memories, notes Science Daily.

These findings indicate that stable short-term memory information exists within a population of neurons with dynamic activity.
Photo: National University of Singapore
The researchers working in The N.1 Institute for Health at the National University of Singapore (NUS), led by Assistant Professor Camilo Libedinsky from the Department of Psychology at NUS, and Senior Lecturer Shih-Cheng Yen from the Innovation and Design Programme in the Faculty of Engineering at NUS, discovered that a population of neurons in the brain's frontal lobe contain stable short-term memory information within dynamically-changing neural activity.

This discovery may have far-reaching consequences in understanding how organisms have the ability to perform multiple mental operations simultaneously, such as remembering, paying attention and making a decision, using a brain of limited size.
The results of this study were published in the journal Nature Communications on 1 November 2019...

The researchers are currently extending these studies to explore of how multiple brain regions interact with each other with the objective of transferring and processing different types of information.
Read more... 

Additional resources  
Journal Reference:
  1. Aishwarya Parthasarathy, Cheng Tang, Roger Herikstad, Loong Fah Cheong, Shih-Cheng Yen, Camilo Libedinsky. Time-invariant working memory representations in the presence of code-morphing in the lateral prefrontal cortex. Nature Communications, 2019; 10 (1)  
  2. DOI: 10.1038/s41467-019-12841-y 
Source: Science Daily

          

Full Time Job - Information Technology Librarian

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Job no: 493111
Work type: Faculty- Librarian
Location: UMBC Campus
Categories: Library


Responsibilities:

As part of the Library Information Technology Services (LITS) division, the I.T. Librarian oversees the daily operations of IT support and AV services for staff computing as well as AV deployment in the Library & Gallery. Works closely with DolT in management of the Library's public computing and AV resources. This position works collaboratively in a diverse and inclusive environment with librarians and staff, both inside and outside of the Library & Gallery, to implement effective and equitable technological solutions including assistive technologies and to identify current and emerging technologies to meet the evolving needs and expectations for an academic library environment. Assesses and documents condition and use of technologies in the building; makes recommendations on existing and emerging technology and resources based on gaps in meeting user needs and emerging trends. The IT Librarian is responsible administering and maintaining library applications including, but not limited to, ILLiad, CONTENTdm, Connexion, Ares, Aleph, and EBSCO Discovery Services (EDS). In addition, the IT Librarian supports efficient use of technology for employees in the Library & Gallery including through management and training for various systems, development of best practices for document management and use of cloud systems, and development of procedures and training for other topics as needed. The position also assists with the coordination and continued development of local digitization projects and with defining and implementing the Library & Gallery's digital preservation strategy. This position also manages and maintains servers for storage and backups. Other duties as assigned.


Required Minimum Qualifications:

  • Requires a Master's degree from an ALA-accredited library school or information science program
  • Knowledge of computer workstations, networking, and computer security.
  • Knowledge of web client and server applications, databases, and Web programming environments.
  • Knowledge or experience working with integrated library systems and the application of technology to enhance effectiveness in library operations.
  • Demonstrated knowledge of technology trends, standards, information technology best practices, and issues in academic libraries.
  • Demonstrated working knowledge of information technology principles, processes, systems and standards, including operating systems, systems security, wireless networking, and digital initiatives and emerging web technologies.
  • Demonstrated experience in progressively responsible supervisory positions, managing multiple priorities.
  • Excellent communication skills (verbal and written)
Preferred Qualifications:


  • Background in computer science or related field
  • Demonstrated experience with system administration and network administration.
  • Experience working with digital repositories or working to develop projects that support locally digitized scholarly content.
  • Experience leading projects or implementing new technologies, preferably in an academic library environment.
  • Experience with Ex Libris products
Screening of Applications Begins:

Review of application materials will begin December 20, 2019 and will continue until the position is filled.


Salary & Benefits:

Position is a 12-month library faculty appointment at anticipated rank of Librarian II. Minimum salary: $65,000, comprehensive benefits. 

The successful candidate will be expected to meet library and university requirements for reappointment, promotion, and permanent status, as outlined in part 6.6 of the Faculty Handbook - http://provost.umbc.edu/faculty-handbook/.

Hours:


This is a full time (40 hrs/wk) position, Monday to Friday.

UMBC is an Affirmative Action/Equal Opportunity Employer. Applications from women, minority group members, veterans and individuals with disabilities are encouraged to apply.


As required by the 1986 Immigration Act, be prepared to present acceptable documentation upon hire showing your identity and that you are a U.S. citizen or an alien who is authorized to work.

Apply here.


          

Keeping Allergen Names Clear and Defined

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The World Health Organization/International Union of Immunological Societies (WHO/IUIS) Allergen Nomenclature Sub-Committee was established in 1986 by leading allergists to standardize names given to proteins that cause IgE-mediated reactions in humans. The Sub-Committee's objective is to assign unique names to allergens based on a critical analysis of confidentially submitted biochemical and clinical data from researchers, often prior to publication to preserve consistency. The Sub-Committee maintains and revises the database as the understanding of allergens evolves. This report summarizes recent developments that led to updates in classification of cockroach group 1 and 5 allergens to animal as well as environmental and occupational allergens. Interestingly, routes, doses, and frequency of exposure often affects allergenicity as does the biochemical properties of the proteins and similarity to self and other proteins. Information required by the Sub-Committee now is more extensive than previously as technology has improved. Identification of new allergens requires identification of the amino acid sequence and physical characteristics of the protein as well as demonstration of IgE binding from subjects verified by described clinical histories, proof of the presence of the protein in relevant exposure substances, and demonstration of biological activity (skin prick tests, activation of basophils, or mast cells). Names are assigned based on taxonomy with the abbreviation of genus and species and assignment of a number, which reflects the priority of discovery, but more often now, the relationships with homologous proteins in related species.


          

Legal: First Party Property Attorney (Miami) - Miami, Florida

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Lydecker Diaz, LLC, a statewide full-service law firm is seeking a first- third year associate attorney to handle defense of first party property damage lawsuits for its Miami office. The position requires the ability to adhere to deadlines, multi-task and handle a high volume of cases. Must be detail oriented, self motivated and a self-starter. Court appearances and taking of depositions will be required. Travel to various courthouses and other locations is expected. Florida Bar admission is required. Excellent benefits. Salary commensurate with experience. Responsibilities-- Managing cases from inception to post-trial Attending hearings, depositions, mediations, and trials Preparing pleadings, discovery demands, discovery responses, motions, and other litigation documents Preparing reports to insurance carriers regarding case status and ongoing activities Ability to prioritize work load based on deadlines-- Ability to be work efficiently and write succinctly-- YourMembership. Keywords: Attorney, Location: Miami, FL - 33131 ()
          

Untempted by the Consequences

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“The women are up to something in Convocation,” the dons of St. John’s College, Oxford, were warned. “We have to go and vote them down.”

The women at issue were led by a young philosopher named G.E.M. (Elizabeth) Anscombe, who was then a tutor at Somerville, one of the oldest women’s colleges at the University of Oxford. Anscombe had come to Somerville in 1946 on a research fellowship. At that time she was a student of Ludwig Wittgenstein, who entrusted her with the translation of his Philosophical Investigations, which appeared in 1953, two years after his death. Now, in 1956, Anscombe was opposing the university’s decision to grant an honorary degree to former U.S. President Harry Truman.

Speaking on the floor of Convocation to her colleagues on May 1, 1956, Anscombe said that her opposition to granting Truman’s degree was based on his responsibility for dropping the atomic bombs on Hiroshima and Nagasaki in 1945. “If you do give this honor,” she asked, “what Nero, what Genghis Khan, what Hitler, or what Stalin will not be honored in the future?” In response, a representative of the Hebdomadal Council, then the university’s chief executive body, argued that Anscombe had overstated Truman’s responsibility. “A great many people were involved in the responsibility of the manufacture and delivery of the bomb,” he told the faculty, “and we cannot select one man as being solely responsible, even if his was the signature at the bottom of the order for the bomb to be dropped.”

Anscombe’s cause was doomed to fail. Reports in the Manchester Guardian and the Times of London claimed that no other faculty echoed her dissenting vote, though subsequent reports indicate that three or four had joined her—and Anscombe later dedicated the pamphlet “Mr. Truman’s Degree,” in which she explained the rationale for her opposition, “with respect, but without permission, to the others who said ‘Non placet.’” In the speech she gave to her colleagues on the day of the vote, she acknowledged that these voices were not going to prevail, saying that she had “no ambition or hope to carry the House with me in this, but my hope is that this honorary degree will not be offered without opposition being expressed.”

Truman received his degree at the university’s Encaenia ceremony on June 20, 1956. In a speech awarding the degree, the Chancellor praised him as “most staunch of allies, direct in your speech and in your writings, and ever a pattern of simple courage.” Anscombe, who had concluded her pamphlet with the warning that she herself “should fear to go” to Encaenia “in case God’s patience suddenly ends,” had kept away from the ceremony, telling the Guardian that she “would spend the day working as usual.”

 

The influence of Wittgenstein on Anscombe’s philosophical writing is immense, in both substance and style.

The protest against Truman was hardly Elizabeth Anscombe’s first foray into public controversy. As an undergraduate in 1939, just a year after entering the Catholic Church under the tutelage of the Dominican friars at Oxford, Anscombe and her friend Norman Daniel published a pamphlet titled “The Justice of the Present War Examined: A criticism based on traditional Catholic principles and on natural reason.” It presented “the results achieved in a series of open discussions held at Oxford both before and after” Britain’s declaration of war against Nazi Germany in September of that year. Anscombe and Daniel concluded that the war against Germany was unjust, partly because it would involve the deliberate massacre of civilian populations.

“We have it,” they wrote, following Thomas Aquinas, “that no one may be deliberately attacked in war, unless his actions constitute an attack on the rights which are being defended or restored. To deny this will be to assert that we may attack any one anywhere, whose life in any way hinders the prosecution of the war, or in any way assists our enemies; and such a conclusion is as immoral as to be a reductio ad absurdum in itself.”

Anscombe and Daniel’s pamphlet did not receive anything like the attention of her protest against Truman seventeen years later, which was picked up by the Associated Press and covered in newspapers across the United States and other parts of the world. (A report from Reuters, under the headline “WOMAN DON FAILS TO HALT TRUMAN DEGREE TO OXFORD,” mistakenly gave her first name as “Gladys” rather than “Gertrude.”) The pamphlet did, however, make enough of an impact that in 1940 the Archbishop of Birmingham wrote to a priest at Oxford complaining that Anscombe and Daniel had it “printed and brought out without submitting it to ecclesiastical authority,” and inquiring as to whether they were “deliberately taking a line opposed to that of the hierarchy of this country.”

Despite the need for some sort of military action against Nazi Germany, Anscombe and Daniel were clearly right on two very important points. First, the war that Britain actually waged against the Axis Powers did involve attacks that were targeted directly at civilian populations and, second, a war carried out by such means does violate a central principle of the church’s just-war teaching. It is possible that the war could have been fought without deploying these tactics, and it might have been just if it had been. But Anscombe and Daniel were correct in predicting that it would not be waged in that way. Acknowledging that “to some their arguments may seem temerarious,” they aimed in their pamphlet “to make the Christian tradition clear, to examine the mind of the Church in a rational and scientific manner.”

While Anscombe and Daniel’s 1939 pamphlet was addressed exclusively to fellow Catholics and Christians, Anscombe’s protest of 1956 had a quite different audience. Indeed, in writing her pamphlet “Mr. Truman’s Degree,” Anscombe saw that many of her Oxford colleagues were prepared to accept a conclusion that she and Daniel had presented as a reductio ad absurdum. These philosophers endorsed a doctrine that Anscombe came to call consequentialism, according to which there are no kinds of action—such as murder, rape, torture, and adultery, for example—that any person is prohibited from doing regardless of the situation he or she is in. According to this doctrine it can be right to “attack any one anywhere,” as long as the balance of the consequences speaks strongly enough in favor of it. Faced with a group that found this conclusion acceptable, Anscombe needed to try a different tack.

 

It was as an Oxford undergraduate that Anscombe met her husband, a fellow Catholic convert named Peter Geach, at a Corpus Christi procession in 1938. They married three years later, and during the first few years of marriage they lived apart from one another. Geach worked in a pine forest as a conscientious objector to World War II while Anscombe studied at Oxford and Cambridge. During this time they had two children—the first of seven they would have together, despite often working at universities in separate cities.

Anscombe became a student of Ludwig Wittgenstein shortly after arriving at Cambridge on a research fellowship in 1942, during which time Geach was engaged in forestry work. Wittgenstein was by then a major figure in the world of philosophy, having published his influential Tractatus Logico-Philosophicus two decades earlier. Many students at Cambridge were extremely devoted to him. The Oxford philosopher Gilbert Ryle would later describe the reverential atmosphere at Wittgenstein’s lectures as “pedagogically disastrous for the students and unhealthy for Wittgenstein himself.” But Anscombe’s own view of this dynamic was quite different. In her remembrances of Wittgenstein, she described the attention he would pay to his students as he helped them work through philosophical questions. “Wittgenstein very often seemed to understand one’s philosophical thought and problems better than one did oneself,” she wrote. “One would say what one thought—then he would amplify it, make it seem more convincing, carry it deeper—and then undo it.”

As a teacher Wittgenstein was notoriously unaccommodating for female students, but he quickly took a liking to Anscombe and would refer to her, affectionately, as “old man.” In his biography of Wittgenstein, The Duty of Genius, Ray Monk writes that on one occasion, when Wittgenstein found that there were no other women students remaining at his lecture, he turned to Anscombe and said, “Thank God we’ve got rid of the women!” A letter that he wrote in 1945 in support of Anscombe’s application for a research fellowship characterized her as “undoubtedly, the most talented female student I have had since 1930, when I began to lecture; and among my male students only eight, or ten have surpassed her.” It was not long before Anscombe would surpass those eight or ten as well.

The influence of Wittgenstein on Anscombe’s philosophical writing is immense, in both substance and style. Both of them attend closely to ordinary speech and other forms of human expression and interaction, and reject the demand that philosophy deliver a theory to resolve the questions that we face. While Anscombe presented arguments for straightforward conclusions in many of her philosophical writings, this was always in a way that gave intense consideration to conceptual difficulties and counterarguments. Meanwhile, others of her writings are like Wittgenstein’s in that they deliver no thesis at all but rather take up a question and simply attack it from all sides. In her remembrances of Wittgenstein, Anscombe wrote that he once reproached her for the tendency they both shared to get stuck in philosophical problems. “You know,” he told her, “you strike me as like a person who is walking along a road and comes to a lamp post which is in his way. And [this person] says: ‘There’s a lamp post. I can’t go on.’ It doesn’t occur to you to walk around the lamp post—I have a prejudice, which is that problems are insoluble.”

Wittgenstein could be critical of Anscombe’s written work to a degree that most academics today could barely imagine. Her notebooks recall how, of some of her writing, “he said, ‘Bought for a farthing’ and ‘Shit on the floor’—though the way he put this latter to me was ‘Not house-trained.’” Her husband Peter Geach once told her that having Wittgenstein come to stay with them “was like having a young atom bomb in the house.” Yet Anscombe also wrote of how “kind and considerate” Wittgenstein was, always prepared to help and advise even when this meant interrupting his work, and of how he “hated meanness” and was not “carelessly amiable or carelessly generous.” (Upon discovering once that Anscombe had no wastepaper basket at her lodging in Oxford, Wittgenstein said “You are a writer, you have to have a wastepaper basket”—and he took her out to buy one.) And she also expressed a wish to capture better in her remembrances of her teacher “how funny he could be—but it is possible that the jokes which came often in his lectures and his talks were just for the moment.”

Anscombe’s attitude toward religious topics stood in stark contrast to Wittgenstein’s. While she was a convert to Catholicism whose earliest encounter with philosophy came in an attempt to formalize a proof of God’s existence, Wittgenstein was raised in a Catholic household but had decided around the age of nine that, as Anscombe put it, “the Christian religion (that Catholic one which they were taught) was all a rubble.” Though some of Wittgenstein’s unpublished remarks from the 1930s show him expressing an openness to Christianity, he is reported to have said, in reference to Anscombe and another Catholic student of his, Yorick Smythies, that “I could not possibly bring myself to believe all the things they believe.” In his posthumous work On Certainty, Wittgenstein described this kind of clash between irreconcilable attitudes as one in which two worldviews are so totally opposed that there is no way to give reasons that can be engaged by the other side. The discovery of having been wrong to such an extent would be such that “the foundation of all judging would be taken away from me.”

Despite all this, at one point in 1950 Wittgenstein asked Anscombe to put him in touch with a “non-philosophical” priest, wishing as Ray Monk puts it “to talk to [the] priest as a priest” rather than “to discuss philosophical problems.” While the priest took this as part of an attempt by Wittgenstein to return to his childhood Catholicism, Anscombe herself reportedly doubted this. There were, however, arrangements made by this priest for Wittgenstein to live the life of a brother in a Dominican priory—a plan that had to be abandoned due to his bad health. When Wittgenstein died in 1951 Anscombe was one of a small group at his side that included Yorick Smythies, who brought with him the priest Wittgenstein had met. It was agreed that, since Wittgenstein had expressed hope that his Catholic friends would pray for him, this priest should be allowed to administer last rites.

Wittgenstein was given a Catholic burial the next morning—a decision that was, as Monk argues, surely improper given his professed lack of faith, even as it reflected the religious intensity with which Wittgenstein had lived.

 

Anscombe’s Intention is an extraordinarily dense and difficult book, even by the standards of contemporary philosophy.

After her contribution to the pamphlet with Norman Daniel, the earliest of Anscombe’s published writings is from 1948, based on a debate she had with C. S. Lewis, who was then a fellow at Magdalen College, Oxford. The debate took place in Oxford’s Socratic Club, and concerned the third chapter of Lewis’s book Miracles, which argues that human thought cannot be relied on “if it can be fully explained as the result of irrational causes.” This argument was supposed to show that the only way to have a reasonable belief in the reliability of human reason is to believe in a supernatural God.

Anscombe criticized Lewis’s argument, claiming that it was based “on a confusion between the concepts of cause and reason.” In evaluating, for example, the quality of the argument in a piece of writing, our concern with whether it expresses good reasoning is not about “the circumstances of its production,” but rather about whether the evidence it offers is sufficient to prove its conclusion. She also argued that the term “explanation” can encompass many different things, and that a causal explanation of human thought and behavior in terms of regular patterns in the universe would not preclude there also being explanations in terms of the reasons why people act and believe as they do. Both of these arguments likely had their roots in Anscombe’s interactions with Wittgenstein, as they mirrored ideas that were central to his Philosophical Investigations, and that Anscombe would develop in her own work of the following decade.

There was for some time a lot of controversy over how Lewis was affected by this episode. Anscombe wrote to Wittgenstein the day after the debate that Lewis had been “much more decent in discussion than I expected, though he was glib and played all sorts of tricks to obscure the issue.” She did add, however, that during the discussion the secretary of the club “started going for Lewis, who had said something about having written the book ‘at a fairly popular level’—he [the secretary] reproached him almost in moral terms, that one should not, for the sake of popularizing, put up a bad argument.” While several of Lewis’s biographers claimed that the debate humiliated him and was the end of his career as a public intellectual, Anscombe later wrote that those who knew Lewis reported no such thing at the time, and noted that Lewis revised the argument of that chapter for the second edition of Miracles, presenting it in a way that she found more appropriate “to the actual depth and difficulty of the question being discussed.”

 

The closing paragraphs of Anscombe’s pamphlet “Mr. Truman’s Degree” raised the question of “why so many Oxford people are willing to flatter” a man who had approved the massacre of entire cities. “I get some small light on this subject,” Anscombe wrote, “when I consider the productions of Oxford moral philosophy since the First World War, which I have lately had occasion to read.” (While her early research interests had been in metaphysics and the philosophy of mind, it was when her Somerville colleague Philippa Foot spent a year visiting in America that Anscombe began reading modern ethicists in order to take over Foot’s course in moral philosophy.) One important strand that Anscombe identified in these philosophers was “a doctrine that it is impossible to have any quite general moral laws.” According to this doctrine:

[S]uch laws as “It is wrong to lie” or “Never commit sodomy” are rules of thumb which an experienced person knows when to break. Further, both his selection of these as the rules on which to proceed, and his tactful adjustments of them in particular cases, are based on their fitting together with the “way of life” which is his preference.… These philosophies, then, contain a repudiation of the idea that any class of actions, such as murder, may be absolutely excluded.

This, again, is what Anscombe would call the consequentialist doctrine that any type of action can in principle be justified by considering its likely consequences. According to this logic, it was because his action ended up saving lives, by bringing an earlier end to the war, that Truman was justified in massacring the citizens of Hiroshima and Nagasaki.

In “Modern Moral Philosophy,” the influential 1958 paper in which she introduced the term “consequentialism,” Anscombe went to greater length in identifying the error that her Oxford colleagues had committed. This followed a BBC radio address given about a year earlier, in which Anscombe had posed the question “Does Oxford moral philosophy corrupt youth?” and answered it in the negative: the youth were not corrupted, she said, since these philosophers only taught the bad moral views that young people held anyway. Anscombe’s 1958 paper began with a whirlwind history in which she dismissed a series of moral philosophers from David Hume (“sophistical”) to Immanuel Kant (“useless”) to John Stuart Mill (“stupid”) to Henry Sidgwick (“dull” and “vulgar”), and then took aim at the “shallow,” “provincial,” and “corrupt” work of her contemporaries. The latter criticism centered on a conception of intentional action that Anscombe located in the work of Sidgwick, according to which a person “must be said to intend any foreseen consequences of [their] voluntary action.” On Anscombe’s reading, Sidgwick used this definition “to put forward an ethical thesis which would now be accepted by many people: the thesis that it does not make any difference to a man’s responsibility for something that he foresaw, that he felt no desire for it, either as an end or as a means to an end.”

Anscombe illustrated the upshot of this thesis with a simple example. According to a view like Sidgwick’s, there is no difference between the responsibility a man has for withdrawing material support from his children if he does this in order to achieve some further end, and the responsibility the same man would have if he was imprisoned for refusing to commit a disgraceful act. In both cases the man foresees that his choice will have the consequence of withdrawing material support from his children. Therefore, according to Sidgwick’s view, in each case the man is responsible in the same way for this outcome.

It is straightforward to extend this analysis to Truman’s decision to bomb the Japanese cities. Truman could foresee that his decision would lead to the deaths of thousands of innocent civilians. Yet, his defenders claim, a similar or greater number of civilians would have been killed had he chosen not to drop the bombs. On this analysis, Truman would have been equally responsible for the civilian deaths in either case. So the only thing that matters is whether he made the choice that led to better consequences overall—that is, to fewer total deaths.

Anscombe noted in “Modern Moral Philosophy” how surprising it was that none of the philosophers who accepted this position displayed any awareness of how their conclusions were “quite incompatible with the Hebrew–Christian ethic.” According to this ethic, she wrote, “there are certain things forbidden whatever consequences threaten,” and faced with the possibility of doing these things “you are not to be tempted by fear or hope of consequences.” But she saw that in her context she could not respond to this situation simply by defending traditional moral absolutes. Instead, the way forward was to begin “by banishing ethics totally from our minds,” in order to consider “simply as part of the philosophy of psychology” the concepts that ethical thinking presupposes. Among these she listed “action,” “intention,” and “wanting”—all of which are explored at length in the short book she had published a year earlier under the simple title Intention.

 

Anscombe’s Intention is an extraordinarily dense and difficult book, even by the standards of contemporary philosophy. It is just ninety-four pages long, comprising fifty-two numbered sections that range in length from a single paragraph to four or five pages. In this space the book treats an exhausting range of topics—and yet it has no obvious structure, no theses introduced at the beginning or stated clearly at the end, and barely any reference to the authors whose work it engages. It baffled several reviewers when it first appeared, and for a while went out of print. Yet when Harvard University Press reissued Anscombe’s book in 2001, the following quotation from the philosopher Donald Davidson appeared on the cover: “Anscombe’s Intention is the most important treatment of action since Aristotle.”

Anscombe would likely have objected that such praise overlooked at least the importance of Thomas Aquinas, whose influence is everywhere in Intention, even though his name appears only in one stray footnote. Anscombe’s daughter, Mary Geach, wrote in 2011 that her mother “drew on [Aquinas’s] thought to an unknowable extent: she said to me that it aroused prejudice in people to tell them that a thought came from him: to my sister she said that to ascribe a thought to him made people boringly ignore the philosophical interest of it, whether they were for Aquinas or against him.” Because of this, rather than repeating Aquinas’s theses and rehearsing his arguments for them—an approach entirely out of keeping with the way Aquinas himself built on the work of philosophers like Aristotle and St. Augustine—Anscombe’s writing appropriates Aquinas’s ideas in a fresh and novel guise, free of scholastic terminology and ready to be engaged by the contemporary reader.

Because of its scope and style, Intention resists easy summary. Anscombe is opposed throughout the book to thinking of intention primarily as a matter of one’s internal psychology—as the objective one has in doing a certain thing, or the willingness to do a thing on a certain occasion. At one point she identifies Wittgenstein as having advanced such a view in his Tractatus: “The world is independent of my will,” Wittgenstein wrote, and so action depends on a “presumed physical connexion” between one’s will and one’s bodily movements. In a notebook that likely dates from the 1950s, Anscombe cited this passage and wrote of feeling “more certain that there is a mistake here than about anything else in the Tractatus.” She continued: “I wish to say that ‘I do what happens’ when I act. The extraordinary thing is that this assumes an air of paradox.” This quoted remark reappeared in the text of Intention, where Anscombe wrote that though “everyone who heard this formula found it extremely paradoxical,” in fact it can be shown to make good sense.

In order to save this remark from paradox, Anscombe argued in her book that we use the concept of intention to describe what happens in most of our ordinary ways of describing human life. Imagine, for example, that you come into Anscombe’s study and find her sitting at her desk, with a pen in her hand that she is moving across the page. What is she doing? Writing, you will answer—and in describing her movements in this way you have already gone beyond a description in terms of physical bodies and forces. Mere physical objects can shatter, rise, and roll down hills, but they cannot write, jump, or walk. To describe a movement with words like these is to describe it as the execution of an intention.

How does this account apply to the case of Truman? The analysis of intention that Anscombe rejected holds that since Truman did not want the citizens of Hiroshima and Nagasaki to die—since their deaths were not part of his ultimate objective—they therefore fall outside the scope of his intention. By contrast, Anscombe argues that any sensible description of what Truman did must include the fact that he used these civilian deaths as a means to his end. These deaths were not merely incidental, since it was by killing the civilians that Truman brought the war to a close. Truman had innocent people killed in order to achieve his aims—and to do such a thing is to commit an act of murder.

 

To do the truth is not merely to grasp or to speak it; it also entails the kind of activism and advocacy that were such a part of Anscombe’s life.

Apart from her scholarly work, Anscombe also wrote and lectured extensively for wider audiences, usually of Catholics, on matters of popular concern. A frequent topic of this popular work is the Catholic teaching on contraception—a topic Anscombe wrote about as early as 1963, in an exchange with the Dominican friar Herbert McCabe in the pages of New Blackfriars. Later on, in an essay from 1972 published in The Human World under the title “Contraception and Chastity,” Anscombe defended what she called the Christian “ideal of chastity” and argued that the use of contraceptives is in conflict with it.

For Anscombe, what made the Christian teaching on sexuality so important was precisely that this teaching was not “traditional”: the teaching put Christians “at odds with the heathen world,” not only in the life of monastics but “as part of the ordinary calling of a Christian.” And, she argued, it is this view of marriage and family life that provides the rationale for the Christian ideal of chastity:

[T]he ground of [Christian] objection to fornication and adultery was that sexual intercourse is only right in the sort of set-up that typically provides children with a father and mother to care for them. If it’s all right to exclude children, if you can turn intercourse into something other than the reproductive type of act (I don’t mean of course that every act is reproductive any more than every acorn leads to an oak-tree but it’s a reproductive type of act) then why, if you can change it, should it be restricted to the married? Restricted, that is, to partners bound in a formal, legal, union whose fundamental purpose is the bringing up of children?

Anscombe’s argument here is supposed to be a reductio ad absurdum of the claim that contraceptive intercourse is permissible: if this is allowed, she says, then all other restrictions on sexual behavior go with it. It seems possible to resist this conclusion by holding that using contraceptives only sometimes would not sever entirely the link between sex and reproduction. Just as a writer lands most of her words in the wastepaper basket, so most of a married couple’s sexual acts won’t result in any children. And what is the difference between using contraceptives and refraining from intercourse during fertile periods in order not to become pregnant?

Questions like these were the focus of two replies to Anscombe’s article that were published in a subsequent issue of The Human World, one by Peter Winch and the other by Bernard Williams and Michael Tanner—all three professional philosophers, the latter two colleagues of Anscombe’s at Cambridge, where in 1970 she had taken up the chair previously held by Wittgenstein. Winch’s reply was short and substantive, arguing that the method of avoiding procreative intercourse does seem to change the character of “an act of intercourse considered as intentional,” in just the same way as taking a contraceptive pill. Williams and Tanner made a similar argument at greater length, and also voiced displeasure with what they called Anscombe’s “offensive” conclusions and spoke of how hard it was “to suppress feelings of outrage at some of her attacks on the spirit of the age, and the relish with which she launches them.”

Anscombe’s reply to these substantive arguments appealed to some simple analogies. In replying to Winch she asked the reader to imagine a man who operates some machinery in the course of doing his job, compared with another who deliberately sabotages this machinery and then manipulates it, perhaps by turning a crank, in a way that is superficially the same as the first man. The “wider context” between the two men’s actions means that there is a difference in what each of them does—since the fact that the second man has sabotaged the machine means that he is not doing his job, or even “operating” the machine in a strict sense at all. So have the contracepting couple “sabotaged” the sex act by preventing it from achieving its natural end. In replying to Williams and Tanner (whom she addressed as “my friendly neighborhood philosophers”) she pointed to the difference between arranging a meeting at a time when one knows a certain person will not be able to come, in order thereby to exclude that person, and physically barring an unwanted person from a meeting. The former, she wrote, “may be correctly describable as doing my organiser’s duties, namely to arrange the meeting.” But in physically barring an unwanted person, “I would be transgressing [those duties] by arranging to refuse him admission.”

This argument raises the question of whether a married couple has any duty toward their would-be children corresponding to the one that Anscombe’s organizer has to his potential guests. That is a question about the end or aim of married life, and such a question cannot be reduced to the casuistic application of moral principles. Here is how Anscombe addressed that wider question in the 1972 essay:

What people are for is to home in on God, God who is the one truth that is infinitely worth knowing, the possession of which you could never get tired of, like the water which if you have you can never thirst again, because your thirst is slaked forever and always. It’s this potentiality, this incredible possibility, of the knowledge of God and of sharing in His nature which Christianity holds out to people and because of this potentiality every life, right up to the last, is infinitely precious. Its potentialities in all things the world cares about may be slight; but there is always the possibility of what it’s for.

In this context, Williams and Tanner’s complaints on behalf of “the spirit of the age,” and their charge that Anscombe was “preaching impoverishment of life,” come into a different light, as she noted in her reply to them: “That one must be prepared to lose one’s life to save it, that ‘being poor in spirit’ is blessed, that what looks like deprivation and mutilation may be the path of life, the alternative death: all this Christianity has indeed taught.” She then added how strange it is “that ordinary chaste and faithful marriage should seem to exemplify” this spiritual poverty: “But that’s what our age is like.”

           

It is hard to imagine a phrase less descriptive of the life of Elizabeth Anscombe than Williams and Tanner’s charge of “impoverishment.” She was, by all accounts, an astoundingly rich personality, not at all mediocre or ordinary. Her house was filled with children as well as all sorts of visitors. She joked and swore, was famous for smoking cigars and drinking champagne, and loved to eat good food and cook it with her children. One great Oxford philosopher, Sir Anthony Kenny, recalls how in his days as a graduate student it was possible to drop into Anscombe’s house “at any hour of day or night and start discussion of a philosophical problem.” Sir Michael Dummett—who also converted to Catholicism, and who disagreed with Anscombe about contraception—recalls that tutorial meetings with her would last up to three hours rather than the usual one hour.

While not a feminist in any usual sense, Anscombe did keep her maiden name (on aesthetic grounds, apparently—“G.E.M. Anscombe” sounded better, she thought, than “G.E.M. Geach”), and she wore pants exclusively, often under a tunic. This made for some good stories. In one, Anscombe entered a restaurant in Boston where she was told that ladies were not permitted to wear pants, and so she took her pants off. In another, someone at the university told her that ladies had to wear skirts when they were lecturing, and so she began carrying a plastic bag with a skirt in it and then putting it on, over her trousers, just outside the lecture room.

The characteristics that made Anscombe one of the most exhilarating and intellectually formidable philosophers of her time also make most of her scholarly work quite inaccessible to non-specialists. Her popular writings, many of which are collected in Faith in a Hard Ground (2008), are a different story, though these too are not the sort of thing one is used to finding in a popular magazine. Her writing is focused, incisive, uncompromising in its commitment to what she called “doing the truth.” To do the truth is not merely to grasp or to speak it; it also entails the kind of activism and advocacy that were such a part of Anscombe’s life. A remark in one of her notebooks glosses this phrase as equivalent to “acting truthfully”—acting, that is, in such a way that this truth that we long for fills us up entirely as its vessel, animating our life and shining forth through our deeds.

In the final hours before her death, Anscombe was attended by her husband and four of her children, and she died as they finished reciting the sorrowful mysteries of the rosary. Anthony Kenny, who had been a student of Anscombe’s and then carried on with her an extensive correspondence via postcard after confessing to her that he was losing his Catholic faith, recently told the story of her burial. Following a funeral Mass in Blackfriars, Cambridge, the mourners processed to the grounds in Ascension Parish where Wittgenstein had been buried some fifty years earlier. Anscombe had secured special permission to be buried next to her teacher, and the grave was dug at double the usual depth, so her husband could be laid to rest above her. Peter Geach followed her there in 2013.

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Hospitality & Tourism: Bilingual All Inclusive Director of Food and Beverage Operations - Marriott Hotels - (19155548) - Fort Lauderdale, Florida

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Here's To Your Journey with Marriott Hotels Resorts Suites Marriott International is the world's largest hotel company, with more brands, more hotels and more opportunities for associates to grow and succeed. We believe a great career is a journey of discovery and exploration. So, we ask, where will your journey take you? The CALA Regional Office - WESTON, located at 1200 S. Pine Island Road, Plantation, Florida, 33324 is currently hiring a Bilingual All Inclusive Director of Food and Beverage Operations. Responsibilities include: The Bilingual All Inclusive Director of Food and Beverage Operations is a key member of the CALA Continent Lodging Service team. Reporting into the VP of Operations, CLS CALA this position provides operational leadership and consultation for All-Inclusive lodging brands and acts as a business partner to the VP Ops and VP & Managing Director, All-Inclusive, as well as GMs, Executive Committee Members, Department Heads, and other Continent team members. Primary responsibilities include driving Operational Excellence, execution of brand & discipline priorities, and technical & business expertise for operations. Location: Plantation, FL or role may be located elsewhere in the region where segment growth is expected. EXPECTED CONTRIBUTIONS Provide consultation & support for all Food and Beverage functions in the continent promoting organizational alignment to the brand, discipline, and business priorities. Act as the All-Inclusive Food & Beverage expert; driving on property incremental sales and marketing opportunities as well as cost management in order to optimize overall operational food and beverage performance. Act as the strategic business partner to the All-Inclusive Operations stakeholders and provides technical and business expertise to assist properties in achieving optimum performance in the balanced scorecard goals including revenue generation. Partner and inform the F&B Concept Development Teams to ensure that Market and Property relevant details are captured and represented in the finished product. Partner to support work processes that drive innovation, enhance brand differentiation, and speed to market. Accountable for aligning Food and Beverage associates on the vision and mission of providing superior branded guest food and beverage experiences. Identify business opportunities or risks by keeping abreast of industry, competitor, economic, and internal trends. Develop processes to enhance communication and sharing of best practices across the continent within and outside the All-inclusive portfolio. Act as the All-Inclusive expert in all Food and Beverage Operations. Fully versed on total Hotel Operations Brand Standards and MI's Quality Assurance processes and programs. Promote and sell ideas persuasively to properties for stimulating business opportunities, improving service, and increasing profitability. Support and coordinate new hotel openings to include market research, concept development, space plan reviews, talent selection, and task force needs. Monitor GuestVoice and appropriate metrics to identify and manage business risks. Ensure consistent execution & pull through of segment, brand and enterprise wide Initiatives, Products, Programs, and Services. Identify opportunities to improve product quality, guest experience, service delivery, and financial performance. Ensure a communication plan is in place to share ideas, best practices, concerns, and execution issues from the market to CLS Maintain close and productive working relationships with the VP Ops and Managing Director - All Inclusive to resolve hotel operational issues and participate in property visits as needed. Respond to and resolves operational requests from key stakeholders. Coordinate the execution of discipline specific training classes. Involved in Recruitment efforts to attract, develop, and retain top talent for operations. Active participant in the development of a global pipeline of talent for Food and Beverage Operations. Assist as needed with other segments Food and Beverage Operations execution of Brand Standards, Products, Programs, and Services. CANDIDATE PROFILE - KEY TALENTS AND EXPERIENCE DESIRED REQUIRED: 7+ years of progressively responsible work experience in hotel industry leading operations disciplines. Above property multi-unit experience preferred. (e.g., combined experience to include food & beverage, spa and retail services, rooms operations, event management, quality assurance and prior strategic leadership roles or GM assignments.). All-Inclusive hotel experience highly preferred Must possess detailed knowledge of the core principles of All-Inclusive Hotel Operations. (Food & Beverage) Ability to operate in a matrix organization. Possess excellent project management skills and ability to independently manage multiple projects and competing priorities. Track record of putting in place strong systems and processes to effectively implement and execute multiple programs. Must have strong knowledge in areas related to all food & beverage and event management, SOPs and P&L budgeting. Luxury experience preferred Resort experience required Must be a self-starter who can work independently and be a strong team player that contributes to the effectiveness of the broader MI team. Proven success prioritizing and managing multiple projects and stakeholders simultaneously. Possess strong oral and written communication skills, excellent interpersonal skills; able to collaborate effectively with General Managers, Executive Committee Members, and Key Stakeholders. Ability to positively influence without direct authority. Ability to manage and excel in a culturally diverse work environment and a champion for diversity. 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Malone Interview (CNBC), Iger Book, Bubble Watch

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People keep talking about how crazy the market is, up more than 25% this year. It's a big year to be sure. But on the the other hand, even though the market has been decent in recent years, it hasn't been particularly bubblicious.

To put the 25% return into context, I think it's a good idea to look at it over 2 years or 3 years.  Since the end of 2017, for example, the market has return an annualized 8.4%/year.  Pretty good to be sure.  Since the end of 2016, its up around 12%/year.  Going back five years, it's up 8.8%/year (these figures exclude dividends).

Not bad at all, but not bubble-like either. If you were going to train an AI machine to look for bubbles, you would look at valuations (interest rate adjusted), sentiment etc. But one of the biggest factors that I would include would be historical returns over various time frames; strong performance reinforces the positive loop of increasing positive sentiment -> higher prices -> better-looking historical returns -> increasing optimism and 'proof' (both statistical and social) of the greatness of stocks etc.

The 10-year return is 10.9%/year, but that's off a depressed level due to the great recession. Over 20 years, the market has gone up only 4%/year.

Here is a table of the S&P 500 index change over various time periods.

S&P 500 Annualized Returns Through November 2019 (excl. dvd)

1-year return:    25.30%
2-year return:      8.39%
3-year return:    11.95%
4-year return:    11.34%
5-year return:      8.81%
10-year return:  10.91%
20-year return:    3.87%
30-year return:    7.55%
50-year return:    7.31%

S&P 500 Annualized Returns Through December 1999 (excl dvd)

1-year return:   19.53%
2-year return:   23.05%
3-year return:   25.64%
4-year return:   24.28%
5-year return:   26.18%
10-year return: 15.31%
20-year return: 13.95%
30-year return:   9.67%
50-year return:   9.36%


This is pretty insane. The annualized return over 5 years to December 1999 was 26%! And we are sort of freaking out that the market is up over 25% year-to-date in a single year, and not even double digits annualized over 2 years.

So anyway, that's why it doesn't really feel like a bubble. People aren't quitting their jobs (to trade stocks), buying new cars (with their capital gains), bigger houses and things like that we saw back in 2000. Most people I talk to still tend to hate stocks, the financial crisis still fresh in their minds.


Iger Book

I just finished the Iger book, and it was also a pretty great read. Iger seems like a genuinely nice guy. CEO's tend to have an image of not being nice guys, so it's great to see someone like him make it to the top. It's possible to be decent, honest and honorable and still do well.

Buffett did mention DIS as one of the well-managed companies (along with GE at one point); his relationship with DIS goes back to when DIS bought Capital Cities during the Eisner years (and Iger was working for Thomas Murphy / Dan Burke). And I think it goes even further back than that, actually.

It's fascinating to read about the events that we've been reading about in the newspapers from the people that were involved. This one involves Buffett / Murphy / Burke, Steve Jobs, George Lucas, Pixar and a lot of what is going on in media today. This connects (unintended) to the Malone interview below.

Anyway, this book is a quick read so go get it. By the way, I have not subscribed to Disney+ yet as I am big into Netflix and there is just so much stuff there that I can barely scratch the surface of what I want to watch (by the time I cancelled the DVD part of my Netflix subscription, I had more than 400 DVD's in the queue). My favorite things are the European cop dramas (French, Belgian, German, Norwegian etc.), the Indian and Japanese shows, and of course many U.S.-based shows too. I just watched The Irishman which is really good (creepy is the special effects to make these close-to-80 year olds look middle-aged), but at the same time I also thought, gee, do we really need another wise-guy movie?

OTT Tangent
People keep talking about the competition in direct-to-consumer streaming and how increasing competition will hurt Netflix etc. This is probably true to some extent; when Netflix was the only game in town, that's one thing, but with many participants jumping in, that's another story altogether.

On the other hand, when you think about it, this is not really an either-or world. People aren't going to sit there and debate whether to switch from Netflix to Disney+ or Apple. Netflix charges $14/month or some such thing, and Disney+ is even cheaper.

A lot of people are still paying $100/month or more for the conventional video package ( I dropped that a couple of years ago mostly because I don't watch most of the channels (ESPN, for example), but what bothered me even more was that they were charging me $14/month for each cable box in the house, which seemed ridiculous to me. Those things can't cost more than $100 (look at Roku at $20; and if it actually does cost more than $100, it's for functionality that I don't need), and they are charging $14/month forever; this makes absolutely no sense.

If you cut the chord, you have $100/month in video budget you can allocate (you still need to pay for the internet), so you can have Netflix, Hulu, Disney+, HBO and a few other things and still be under $100...


Malone Interview
There are a few annual events that are really exciting to me. Of course the Berkshire annual meeting (I just watch the video later), annual report, JPM annual report etc.

And another one of those is the CNBC John Malone interview by David Faber. Faber is one of the few people (of the reporters/anchors), if not the only one, who seems to understand the market and business.

Anyway, I jotted down some notes while watching the recent interview (done during the Liberty Media investor day). This is not everything, though, but a large part of it. He also talked about regulation, GOOG etc, for example, so go check out the video.

Here are Malone's thoughts on various topics:

Who is best positioned in streaming right now?
Malone answered by rephrasing the question to, "Who will be around in five years?"
Disney and Netflix.

DIS
Disney has great content, a great global brand, but doesn't have a large direct relationship with customers so must piggy back on those who do, like Verizon.

NFLX
Netflix, so far in the lead, good base / revenue stream.

AAPL
Apple may surprise. Slim content, but has great distribution in their direct customer relationships. They offer free for one year to buyers of AAPL products etc...
AAPL has optionality; see how it goes and decide how much they want to spend (how much they can afford).

HBO, AMZN
HBO is a decent service, but doesn't have the revenue stream to match Netflix.
AMZN has a totally different monetization strategy so... not primary biz.
Content is for marketing. AMZN may evolve to become a bundler of others' content

Tech companies want to be the platform, get info on customers, be gateway,
let others waste money on content.

DIS will be successful.

Direct relationship w/ customer in scale with growth and pricing power is a powerful business model.
DIS knows they need direct consumer relationship.

HBO Max: HBO content budget was $2bn/year.
If you want HBO, you already have it, so not much gain in new customers in the U.S.?   Malone doesn't see the growth. Maybe even attrition.
HBO budget is not enough to protect for the long term.  Takes years to develop content internationally. Don't own rights to intl distribution.  Problem seeing scale at HBO to get to top of direct consumer biz.  HBO is the same as it's been for 25 years. If you want it, you already have it so where is the growth?HBO may capture wholesale spread (as big bundle moves to direct).

ATT will face challenges. Historically has been the biggest dog in every fight, but not now, and not in this space (streaming media). About scale and globality. Need global scale, or won't get enough scale to compete in this space. This will be the challenge for ATT, HBO. FANG companies are all global. If you're only in the U.S., how do you compete?

Sports is glue that keeps big bundle together... will eventually blow up. Not sure when... big bundle still overpriced due to sports content...

Content Cost
At some point, hail Mary passes for some will prove to not be working so content cost will moderate. Some will fail (and stop spending) etc...

NFLX will have to moderate spend at some point.  Bundling of these services will happen too. Distributors may bundle too, if it reduces churn etc... will evolve like traditional cable. Comcast offers Netflix etc.

Cord cutting will level off. Erosion won't stop completely, though...

Cutting video increases margins at cable companies as margins for broadband is higher. Happening naturally.

Satellite will end up serving people with no other options, rural etc.

Linear TV will lose subscribers, ads, but as you get direct relationships, value of ads go up as you know more about customers.  Ad rev potential goes up; more focused ads etc.  Have to fight decline in reach due to decline of big bundle.  Provide content direct through app and sell content to others etc. Random access via app; if you subscribe to Discovery Channel, you get stuff through app too (not everything).

Cable industry changed when congress changed retransmission constraints; Margins started to go down. Content providers were able to extract more and more...

Will be profitable for people with unique situations, consistent, stable demand, pricing power, level of uniqueness...  those businesses ultimately gets regulated. 

Discovery
Discovery owns content globally, generating free cash, need to migrate to direct to consumer.
Malone bought more stock this week (November 2019).  Discovery will solve issues. Stock is dramatically undervalued. Malone bought $75 mn worth of stock. Growing, generating free cash. Market cap to levered free cash flow, cheapest on screen... They own all their content, generates tons of cash, investment grade b/s, they are growing while others are shrinking (5.5x cash flow). Cheap for good company...
Malone paid $28.03/share. 

CBS/VIA
They have no global presence. Lot of content is bought. CBS is totally dependent on sports rights so not sure about long-term profitability.  Not sure if CBS has enough power to carry all the channels.
VIA underinvested for many years, bought back stock at high prices, tactical mistake.
How important is MTV, Nickleodean to distributors? Question sustainability of model, and also they are U.S. only.

Yes, stock is historically cheap, but...  licensing out content to others. Ice cube melts faster when you don't put content on your own channel.

CBS/VIA needs to get global for long term sustainability. Find niche, glue to make customers sticky. Something unique.

Lions Gate
Sold LionsGate; didn't see them execute strategy of using library/content to drive Starrs. They focused too much on selling content instead of driving their own distribution.

Need global scale, or niche in small area that big guys don't care about to survive.

Wired and Wireless Together
Liberty Global followed strategy based on belief that combination of wired and wireless would lead to synergies. Turned out to be true.  Belgium, Holland (combined with Vodaphone).  Once they built scale, they were able to acquire. Synergies were real and very substantial.

In U.S, for Charter, same idea. Keep growing until they understand the economics of a combination. At the moment, not far along enough on that path.  Once scale is achieved, think about building own network. Hybrid tranmission over time. Could be joint ventures, mergers etc.

Malone interested in Altice, but Patrick wants control etc...

Uber
Not an expert, but doesn't understand Uber, how is scale going to make it profitable? Like selling hot dogs at a loss and making it up in volume. Can't see how scale changes economics. Can't understand why Dara took job.

Politics
Worries about attack on success and wealth in this country.
Worries about where country is going.

If Warren wins, wealth destruction will exceed wealth transfer.  Has places in Ireland, Canada, Bahamas etc... (that he can escape to),  but Malone rather stay here, be optimistic about balance.

Malone is Libertarian, would vote for Bloomberg.

Trump has right strategy, but not the right guy; he doesn't build a team. A lot of people that worked for him trying to take him down now. 


          

Why “5-Year Plan” is Stupid: A Career Path in Drug Discovery and Commercialization, Nov 25

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We are often taught that the best plan wins. We see it in movies and sports all the time. From high school, career counselors help us plan to get into the best college, then best graduate school and ultimately through to our professional lives. L.-C. Campeau’s experience is quite the opposite. This talk will meander through the peaks and valleys of his formal training and professional career. He will share some of his thoughts on personal development and key insights from his last 12 years in professional life.

Dr. Campeau obtained his Ph. D. degree in 2008 with the late Professor Keith Fagnou at the University of Ottawa in Canada as an OGSST & NSERC post-graduate scholar, after completing his B.Sc. in Biopharmaceutical Sciences. He first joined Merck Research Laboratories at Merck-Frosst in Montreal in 2007. During his tenure at Merck-Frosst, L.-C. amassed several scientific accomplishments and pipeline impacts, including key contributions to the discovery of Doravirine which was recently approved by the FDA for the treatment of HIV and sold under the brand name Pifeltro™ and Delstrigo™. In 2010, he moved from Montreal to New Jersey, where he has served in roles of increasing responsibility ever since including Director and Head of the Catalysis and Automation Laboratory and then Director in Process Chemistry, where he led teams through very challenging assignments on manufacturing route development. In 2016, L.-C. was appointed Executive Director. He is currently the Head of the Process Chemistry and Discovery Process Chemistry groups, leading a team of >85 smart creative scientists at all Discovery sites and at the CMC hub in Rahway, responsible for eliminating synthetic bottlenecks to accelerate the discovery of novel therapeutics all the way through manufacturing route definition and filing of new products.
          

Multi-Scale Structure Control for Advanced Functional Materials, Dec 5

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Abstract: Economic growth demands better products; hence, better materials. Specifically, product space in energy, defense, aerospace, and automotive industries requires materials that are multi-functional, lightweight, reliable, and tough. In addition, environmental regulations require sustainability. Comprehensive optimization of these requirements is possible through multi-scale structure control in multi-material systems. In this talk, I will discuss how we can control structure from nano-to-macro-scale using additive manufacturing and solution synthesis routes. Examples from hierarchical composites and ceramics will be provided with a design perspective. The use of kHz-range vibrations in local three-dimensional structure control will be introduced. Our recent work showed that vibration-assisted fused filament fabrication (VA-FFF) technique enhanced strength, toughness, and reliability of short-fiber-reinforced composites. We also reported improved mechanical, electrical, and optical properties in polymers via quantum dots and nano-scale structure control. The mechanistic origins of the toughness and reliability increases in additively manufactured biomimetic porous materials will be detailed. I will describe machine learning and high-throughput approaches towards the discovery of new electro-active material systems for the next-generation product innovation. In addition, the discussion will include evidence-based engineering education approaches and problems. For example, sustainable innovation of better products is strongly correlated to creativity at individual level, but how can we cultivate creative engineers? I will exemplify the use of virtual reality and artificial intelligence education approaches to enhance creativity and diversity.

Biography: Dr. Keles is an Assistant Professor of Chemical and Materials Engineering at San Jose State University. He received his B.S. and M.S. degrees from the Department of Metallurgical and Materials Engineering at Middle East Technical University, and his Ph.D. in Materials Engineering from Purdue University in 2013. Following, he joined Illinois Institute of Technology as a research associate, where he investigated the reliability of porous glasses and porous pharmaceutical compacts. His work on the deviations from Weibull statistics in porous ceramics was highlighted at the Gordon Research Conferences and awarded by the American Ceramic Society. His current research interests are multi-scale structure control, materials informatics, and engineering education. In 2019, Dr. Keles was selected as the advisor of the year at SJSU for his contributions to materials student clubs. He is also a photographer and digital artist who uses aesthetically appealing images and computer visualizations to improve student engagement, to aid student learning, and to foster creativity in engineering students. His work at the intersection of engineering, education, and arts was also highlighted in the The Member Journal of TMS.
          

E4 Sets Premiere Date For ‘Star Trek: Discovery’

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Star Trek: Discovery will premiere on E4 on Sunday December 15th at 8pm, it has been announced.

The post E4 Sets Premiere Date For ‘Star Trek: Discovery’ appeared first on TVWise.


          

Entertainments Duty Act - 21 Protection of informers from discovery

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Protection of informers from discovery Subject to this section, no complaint as to an offence alleged to have been committed under this Act or any rules made thereunder shall be a...
          

Protecting users from government-backed hacking and disinformation

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Google's Threat Analysis Group (TAG) works to counter targeted and government-backed hacking against Google and our users. This is an area we have invested in deeply for over a decade. Our daily work involves detecting and defeating threats, and warning targeted users and customers about the world’s most sophisticated adversaries, spanning the full range of Google products including Gmail, Drive and YouTube.

In the past, we’ve posted on issues like phishing campaigns, vulnerabilities and disinformation. Going forward, we’ll share more technical details and data about the threats we detect and how we counter them to advance the broader digital security discussion.

TAG tracks more than 270 targeted or government-backed groups from more than 50 countries. These groups have many goals including intelligence collection, stealing intellectual property, targeting dissidents and activists, destructive cyber attacks, or spreading coordinated disinformation. We use the intelligence we gather to protect Google infrastructure as well as users targeted with malware or phishing.

Phishing

We’ve had a long-standing policy to send users warnings if we detect that they are the subject of state-sponsored phishing attempts, and have posted periodically about these before. From July to September 2019, we sent more than 12,000 warnings to users in 149 countries that they were targeted by government-backed attackers. This is consistent (+/-10%) with the number of warnings sent in the same period of 2018 and 2017.

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Distribution of government-backed phishing targets in Q3 (Jul-Sep 2019)

Over 90 percent of these users were targeted via “credential phishing emails” similar to the example below. These are usually attempts to obtain the target’s password or other account credentials to hijack their account. We encourage high-risk users—like journalists, human rights activists, and political campaigns—to enroll in our Advanced Protection Program (APP), which utilizes hardware security keys and provides the strongest protections available against phishing and account hijackings. APP is designed specifically for the highest-risk accounts.

In the simple phishing example below, an attacker has sent a phishing email with a security alert lure from “Goolge” suggesting the user secure their account. The user clicks the link, enters their password, and may also get asked for a security code if they have two-factor authentication enabled, allowing the attacker to access their account.

sample gmail lure.png

Sample lure used to phish Gmail users

Threat detection

Last week at CyberwarCon, we presented analysis about previously undisclosed campaigns from a Russia-nexus threat group called “Sandworm” (also known as “Iridium”). It’s a useful example of the type of detailed threat detection work that TAG does. Although much of Sandworm’s activity targeting Ukraine and their attacks against the 2018 Winter Olympics have been covered publicly, some campaigns have not been reported. 

In December 2017, TAG discovered a series of campaigns from Sandworm attempting to deploy Android malware. The first campaign targeted users in South Korea, where Sandworm was modifying legitimate Android applications with malware. They then uploaded these modified apps to the Play Store using their own attacker-controlled developer accounts. During this campaign, Sandworm uploaded eight different apps to the Play Store, each with fewer than 10 total installs. 

malicious apps targeting users in south korea.png

Malicious apps targeting users in South Korea

We also identified an earlier September 2017 Android campaign from Sandworm where they used similar tactics and deployed a fake version of the UKR.net email app on the Play Store. This application had approximately 1,000 total installs. We worked with our colleagues on the Google Play Protect Team to write detections for this malware family, and eliminate it.

In November 2018, we saw evidence that Sandworm shifted from using attacker-controlled accounts to try and upload malicious apps to compromising legitimate developers. Throughout November, Sandworm targeted software and mobile app developers in Ukraine via spear phishing emails with malicious attachments. In at least one case, they compromised an app developer with several published Play Store apps—one with more than 200,000 installs. 

After compromising the developer, Sandworm built a backdoor in one of the legitimate apps and attempted to publish it on the Play Store. They did this by adding their implant code into the application package, signing the package with the compromised developer’s key, and then uploading it to the Play Store. However, the Google Play Protect team caught the attempt at the time of upload. As a result, no users were infected and we were able to re-secure the developer’s account.

Disinformation

TAG is one part of Google and YouTube’s broader efforts to tackle coordinated influence operations that attempt to game our services. We share relevant threat information on these campaigns with law enforcement and other tech companies. Here are some examples that have been reported recently that TAG worked on:

  • TAG recently took action against Russia-affiliated influence operations targeting several nations in Africa. The operations use inauthentic news outlets to disseminate messages promoting Russian interests in Africa. We have observed the use of local accounts and people to contribute to the operation, a tactic likely intended to make the content appear more genuine. Targeted countries included the Central African Republic, Sudan, Madagascar, and South Africa, and languages used included English, French, and Arabic. Activity on Google services was limited, but we enforced across our products swiftly. We terminated the associated Google accounts and 15 YouTube channels, and we continue to monitor this space. This discovery was consistent with recent observations and actions announced by Facebook. 

  • Consistent with a recent Bellingcat report, TAG identified a campaign targeting the Indonesian provinces Papua and West Papua with messaging in opposition to the Free Papua Movement. Google terminated one advertising account and 28 YouTube channels.

Partnerships

TAG works closely with other technology companies—including platforms and specialized security firms—to share intelligence and best practices. We also share threat information with law enforcement. And of course there are multiple teams at Google at work on these issues with whom we coordinate. 

Going forward, our goal is to give more updates on the attacks that TAG detects and stops. Our hope is that shining more light on these actors will be helpful to the security community, deter future attacks, and lead to better awareness and protections among high-risk targets.


          

'Monster' black hole found. Scientists didn't think stellar black holes could be so big

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An international team of scientists say they have discovered a stellar-mass black hole with a mass 70 times greater than the sun — so large it defies current theories on how black holes of its kind form. The discovery of the “monster” black hole was announced this week and reported in the latest issue of Nature. The […]

The post 'Monster' black hole found. Scientists didn't think stellar black holes could be so big appeared first on RocketNews | Top News Stories From Around the Globe.


          

rev.joshua skirvin commented on the blog post 'DISCOVERY OF THE CENTURY | “This Will Change The Entire Humanity” | Gregg Braden and Bruce Lipton'

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rev.joshua skirvin commented on the blog post 'DISCOVERY OF THE CENTURY | “This Will Change The Entire Humanity” | Gregg Braden and Bruce Lipton'

          

rev.joshua skirvin posted blog posts

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rev.joshua skirvin posted blog posts

          

Patient Care Programs Coordinator ~ Vanderbilt Eye Institute | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient
          

Team Leader (m/f/d) – Biomarker discovery in Ludwigshafen am Rhein/Germany

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AbbVie (NYSE:ABBV) is a global, research-based biopharmaceutical company formed in 2013 following separation from Abbott Laboratories. The company's mission is to use its expertise, dedicated people and unique approach to innovation to develop and market advanced therapies that address some of the world's most complex and serious diseases. AbbVie employs approximately 30,000 people worldwide and markets medicines in more than 170 countries. For our location in Ludwigshafen, Germany we are…
          

Comment on Is US Oil Production Growth Slowing??? by Dennis Coyne

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Matt, The shock model is top down rather than bottom up. I take World discovery data and fit a dispersive discovery model to that data, with an assumed total of 2800 Gb for conventional discoveries. No attempt is made to break out the discoveries by nation. As the model is for World output (also not broken down by nation) I do not have an answer for (a). If you are interested you could look at Laherrere's work. https://aspofrance.org/2018/08/31/extrapolation-of-oil-past-production-to-forecast-future-production-in-barrels/ Oil Sands model and tight oil model shown below. I agree Oil sands will mostly moderate the decline, the peak will mostly be about tight oil.
          

Tips Originating From A San Diego Video Production: Pre-Interview Your Subjects

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dictionary.comWithin day-to-day of my discovery, a story in the Arkansas Democrat-Gazette (via Associated Press) noted that Kroger was creating a majo...
          

16 educators share their digital learning strategies

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Digital learning has limitless possibilities--get some inspiration from how these educators are using edtech tools in their classrooms, like this male teacher helping students on laptops in the classroom.Digital learning tools are invaluable when they're used by confident educators. In fact, when used appropriately, digital and mobile learning resources engage students--and they can even help boost achievement. Online literacy platforms, virtual field trips, STEM simulations and modeling--these are just some of the tools that help elevate instruction in classrooms across the country. Here, 13 educators share snapshots of the digital learning tools they're using in their classrooms. I use edtech in my classroom to differentiate instruction and take my literacy curriculum to the next level. To accomplish this, I use Achieve3000, a digital platform designed to support accelerated literacy growth through differentiated content and assessments. This program gives my class access to digital texts and news articles that are adapted to each student’s independent reading level. I know my students are engaged when many of the article topics result in classroom debates and discussions for later research and presentation. Most importantly, my students are able to track their individual progress on the program. They are extremely proud when they are able to chart the increases in their Lexile levels as their reading comprehension skills improve. Digital learning tools support me in keeping my literacy curriculum current, in tailoring instruction to meet the needs of my students, and in showing my students the results of their hard work and efforts. By Michelle Downey, English Department, Piedmont High School Simply say the words ‘field’ and ‘trip’ in front of a classroom of students, and the excitement becomes visible. While teachers have always known the value field trips bring, we also are familiar with the logistical planning and budgeting that goes into them. Thanks to the power of technology, teachers now have the ability to introduce students to a variety of powerful experiences without ever having to leave the classroom. Free resources from TGR EDU: Explore, a career exploration program from Tiger Woods’ TGR Foundation and Discovery Education, make my field trips more accessible than ever. Recently, I took my class on a virtual field trip to Menlo Park, California, where we received a behind-the-scenes look at Facebook’s headquarters. As a class, we explored some of the innovative careers that fuel the Silicon Valley powerhouse, and modern technologies that gather data to solve problems--without leaving the classroom. These virtual field trips help students visualize their ambitions, see it in action in the real world, and strive for every career possibility. By Josh Prater, United States History Teacher at Pasadena ISD, Sam Rayburn High School Districts across the U.S. know the familiar pressure of state assessments. This pressure only intensifies when punitive measures result from assessment scores. I’ve found that digital tools are incredibly helpful in ensuring that we’re meeting state standards while also serving our main stakeholders: students. Educators at Oxford Community Schools use Illuminate Education to manage and track student data and assessments, gain a view into student progress, and, most importantly, support the whole child. We’ve paired a data-driven approach with a multi-tiered system of support (MTSS) to ensure every student is receiving what they need to be successful inside and outside of the classroom. Without the help of digital learning technology, this simply wouldn’t be possible. By Ken Weaver, Deputy Superintendent of Curriculum & Instruction, Oxford Community Schools Being able to help staff and students learn the latest skills and pedagogies related to technology in education is a passion of mine. In my professional role, I’m deeply aware of the benefits that digital learning brings to the classroom. Nipissing-Parry Sound Catholic District School Board uses Edsby, a comprehensive K-12 learning and data system, to keep our thousands of teachers, students and parents in-the-loop about progress and updates. And I’ve seen the benefit on the parent side as well – my own son just started school, and I can’t tell you how great it is to get a notification about what he’s been working on in class. Edtech is a game changer, especially when it’s such a comprehensive single platform, and so user-friendly. By Peter Anello, Technology-Enabled Learning and Teaching (TELT) Contact, Nipissing-Parry Sound Catholic District School Board When the district I work in announced our transition to a phonics-based literacy approach using a new reading program two years ago, I was a little skeptical. Gradually moving toward a blended learning environment for teaching reading meant we had to trust a program to deliver effective lessons that meshed well with teacher support. We all went into training with some concerns. Some of my students with reading disabilities came to my class reading 35 words a minute. Without adequate progress, they’re liable to feel defeated and believe that their inability to read is just part of their school experience. During the first year using the new program, Reading Horizons Discovery, the students and I were actively learning it together. In that time, I grew confident with the program and saw student progress I’d never seen before. To see them smile and get to 90 words a minute made my year. We usually start with a whole-group lesson. I like to get my students standing up and working around the room before they log in to their computers for a lesson. During this time, I use my assessment data to pull students aside for individual lessons based on who didn’t pass the last lesson or who needs more support. The computer component allows me to identify what my students understand and what they don’t so that I can provide help where they need it. While the computer components of my class are beneficial for both myself and my students, walking through activities face-to-face with students is still crucial.
          

5 new strategies for digital content

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Using digital content can save teachers time and bring real-world relevance to classrooms.For the past decade of my career, I’ve worked to empower and inspire educators in their use of digital content and technology. From teaching educators in graduate level courses and delivering school level professional development to producing digital learning content and designing educational products and services, my career has had one common purpose: to learn how to best support educators’ use of digital content. This work has been informed by hours interviewing, surveying, observing, and conversing with educators in all roles, grade-levels, and subject areas. Throughout this process, I have observed time and again that when we give educators practical strategies to use digital content, they are more effective at teaching with that content and engaging students in the learning process. Below are five new strategies educators at any level can use to more effectively use digital content to jumpstart classroom learning: Try to discover and implement one new instructional strategy per week to grow your teacher toolbox. With so many requirements of teachers, professional learning can sometimes take a back seat. Practical professional learning can be as easy as trying one new idea for sparking conversations, jumpstarting writing, and exploring concepts. One of my favorite strategies, Snowball Fight, asks students to write and reflect on what they learn at intentional pause-points in a video. After writing a fact they learned from the prior segment, students crumble their papers and toss them into the middle of the room (not at each other!). After the next video segment, students pick up a different paper and add another fact related to what they learned. As the process repeats and wraps-up, each paper provides an opportunity for discussion and reflection to correct misunderstandings and dive deeper into the content being learned through multiple perspectives. Offer students shared learning experiences through virtual field trips that take your students outside of your classroom walls. Speaking of snow, one of my favorite times of the year is when I travel to Churchill, Manitoba for the annual polar bear migration. Each fall, students come along on our journey to virtually to ask questions of scientists, observe polar bears in their native habitat, and learn how the tundra is connected to their homes. These “event-based virtual field trips create a single point in time where classrooms from around the world connect to form a unique and diverse community that takes a deep-dive on a particular topic or moment in history.” I encourage all educators to integrate Virtual Field Trips into their classroom instruction. It is a great way to expand your students’ horizons.  Related content: 5 ways to get the most out of virtual field trips Enable students to remix content and apply what they learn in a digital medium. Content creation and collaboration spaces empower students and teachers to design, build, and share content in creative ways. With high quality content creation tools, students can create a concept map, organize a digital portfolio, record and upload a read-aloud, prepare a scientific explanation, or produce a character analysis. Giving students opportunities to apply their knowledge supports each of the Four C’s that are pivotal for student success. Connect with other educators to learn practical ideas for digital content integration. Whether in-person or online, professional learning networks (PLNs) continue to provide a safe place for educators to collaborate and continue learning. Through our surveys, we continue to hear that educators want to share resources and connect with other like-minded educators. By getting involved in a community like the Discovery Educator Network, you can access ideas, pictures, and videos demonstrating how other teachers use digital content in their classrooms.
          

OSGeoLive Distro Opens Doors to Geospatial Worlds

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OSGeoLive is a unique Linux distro. It pulls together a large library of Linux tools and applications that support geospatial workloads. It is not designed to be a general usability Linux operating system, but if you add the software it's missing, you can happily use it for other computing tasks.

I was particularly intrigued by some of its standalone applications and Web app offerings. Browsing through this distro's feature tools was a fun-filled discovery experience.

Nothing needed to be set up or configured. One click led to another. With each new screen came interesting information that teased my inquisitive mind. The experience actually sparked an interest in the world of geospatial elements.

Read more


          

Legal: Associate Attorney - Albany, New York

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Busy Albany litigation firm seeks associate attorney with 3 to 4 years of experience in civil litigation. Applicant should have experience in handling discovery including drafting demands/responses and conducting depositions. Good research and writing skills are necessary. The firm offers a competitive salary and a solid opportunity for career development in a positive, professional environment. Please send resumes and cover letter with salary requirement to Edwin Negron at . All submissions will be kept strictly confidential. ()
          

PNA length restriction of antibacterial activity of peptide-PNA conjugates in Escherichia coli through effects of the inner membrane

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PNA length restriction of antibacterial activity of peptide-PNA conjugates in Escherichia coli through effects of the inner membrane

Goltermann, L., Yavari, N., Zhang, M., Ghosal, A. & Nielsen, P. E., 2019, In : Frontiers in Microbiology. 10, MAY, 8 p., 1032.

Research output: Contribution to journalJournal articleResearchpeer-review

Peptide Nucleic Acid (PNA)-peptide conjugates targeting essential bacterial genes are showing promise as antisense antimicrobials in drug discovery. Optimization has focused on selection of target genes and exact localization around the ribosome binding site, but surprisingly a length optimum around 10-12 nucleobases has been found. Addressing this observation, we have investigated the relationship between PNA-length, PNA-RNA duplex stability and antimicrobial activity in E. coli in more detail. For PNAs of identical length of ten nucleobases the expected reverse correlation between the thermal stability (Tm) of the PNA-RNA duplex and the MIC for single mismatched PNAs was found. Also the expected direct correlation between the length of the PNA and the PNA-RNA duplex stability was found. Nonetheless, 10-mer PNAs [in a 6-18 mer extension series of (KFF)3K- and (RXR)4 conjugates] were the most active as antisense antimicrobials in both wild type E. coli MG1655 and AS19, suggesting that the size constraint is related to the bacterial uptake of PNA-peptide conjugates. This conclusion was supported by flow cytometry data showing higher bacterial uptake of shorter PNA fluorophore labeled conjugates. Interestingly, the size-limited uptake seems independent on outer membrane integrity (AS19), and thus the results suggest that the inner membrane limits the molecular size for peptide-PNA passage.

Original languageEnglish
Article number1032
JournalFrontiers in Microbiology
Volume10
Issue numberMAY
Number of pages8
ISSN1664-302X
DOIs
Publication statusPublished - 2019

          

Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

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Structure-activity study, characterization and mechanism of action of an antimicrobial peptoid D2 and its D- and L-peptide analogues

Greco, I., Hansen, J. E., Jana, B., Molchanova, N., Oddo, A., Thulstrup, P. W., Damborg, P. P., Guardabassi, L. & Hansen, P. R., 2019, In : Molecules. 24, 6, 16 p., 1121.

Research output: Contribution to journalJournal articleResearchpeer-review

Methicillin-resistant Staphylococcus pseudintermedius (MRSP) constitutes an emerging health problem for companion animals in veterinary medicine. Therefore, discovery of novel antimicrobial agents for treatment of Staphylococcus-associated canine infections is urgently needed to reduce use of human antibiotics in veterinary medicine. In the present work, we characterized the antimicrobial activity of the peptoid D2 against S. pseudintermedius and Pseudomonas aeruginosa, which is another common integumentary pathogen in dogs. Furthermore, we performed a structure–activity relationship study of D2, which included 19 peptide/peptoid analogs. Our best compound D2D, an all d-peptide analogue, showed potent minimum inhibitory concentrations (MICs) against canine S. pseudintermedius (2–4 µg/mL) and P. aeruginosa (4 µg/mL) isolates as well as other selected dog pathogens (2–16 µg/mL). Time–kill assays demonstrated that D2D was able to inhibit MRSP in 30 min at 1× MIC, significantly faster than D2. Our results suggest that at high concentrations D2D is rapidly lysing the bacterial membrane while D2 is inhibiting macromolecular synthesis. We probed the mechanism of action at sub-MIC concentrations of D2, D2D, the l-peptide analog and its retro analog by a macromolecular biosynthesis assay and fluorescence spectroscopy. Our data suggest that at sub-MIC concentrations D2D is membrane inactive and primarily works by cell wall inhibition, while the other compounds mainly act on the bacterial membrane.
Original languageEnglish
Article number1121
JournalMolecules
Volume24
Issue number6
Number of pages16
ISSN1420-3049
DOIs
Publication statusPublished - 2019

          

Administration, Clerical: Litigation Paralegal - Steady Hours - Albany, New York

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Experienced Litigation Paralegal needed for a Albany firm. Convenient Location - Free Parking. Ideal candidates will have 4-6 years of Litigation experience and some knowledge of commercial real estate transactions. Position involves independently preparing discovery responses and motions in State and Federal courts, simple research, reviewing documents, interacting with clients and claim representatives, preparing matters for trial, and associated clerical tasks. This is an excellent opportunity for a great candidate looking for a career position. Apply today! We are an equal employment opportunity employer and will consider all qualified candidates without regard to disability or protected veteran status. ()
          

High Times for Pathway Discovery: Phytocannabinoids - Origins, Biosynthesis and Synthetic Biology

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High Times for Pathway Discovery: Phytocannabinoids - Origins, Biosynthesis and Synthetic Biology

Gülck, T., 2019, Department of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen.

Research output: Book/ReportPh.D. thesisResearch

Phytocannabinoids are a diverse group bio-active natural products found in flowering plants like Cannabis sativa, some liverworts and a few fungi. In humans, they interact with endocannabinoid receptors, ligand-gated ion channels and transcription factors making them potent sources for medicine and popular recreational drugs. In fact, phytocannabinoids are very effective in the treatment of neuropathic pain, chemotherapy-associated nausea, anxiety and AIDS-related loss of appetite. Unfortunately, only few phytocannabinoids are accessible in sufficient amounts that enable clinical trials or product development. My research addresses this issue through the advancement of biotechnological production methods such as heterologous biosynthesis. Heterologous biosynthesis means constructing a biosynthetic pathway in an organism other than the original producer and has the potential to make greater quantities of rare phytocannabinoids accessible. This requires in-depth knowledge of the involved enzymes, their encoding genes, regulation and subcellular localization. In this thesis, I present gene discovery of cannabigerolic acid synthase, the last unknown step in cannabinoid biosynthesis in Cannabis sativa. Furthermore, we use this gene to bioengineer the heterologous hosts Nicotiana benthamiana (tobacco) and Saccharomyces cerevisiae (yeast) towards production of cannabinoids. Our bioengineering work includes biotechnological glycosylation of cannabinoids in yeast. This achievement expands the chemical space within cannabinoids and increases the prospects for cannabinoids as drug leads.
Original languageEnglish
PublisherDepartment of Plant and Environmental Sciences, Faculty of Science, University of Copenhagen
Publication statusPublished - 2019

          

Breath of the Wild Link's bombs are even scarier and more versatile in Super Smash Bros. Ultimate than we thought

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Link's Breath of the Wild redesign in Super Smash Bros. Ultimate saw him come equipped with his remote bombs as a special move. Just as they sound, these explosives can be thrown and detonated at will, and we recently got a glimpse at just how potent they can be thanks to FURY|RaZe and their discovery of the bomb drop loops.

Well, RaZe is back with another Link video this time showing a series of clips that further prove ...


          

Legal: Litigation Paralegal - Los Angeles, California

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Please make sure to include a resume when applying. Covington & Burling LLP has an immediate opening for a -mid-level Litigation Paralegal with work experience gained at Amlaw 100 firms or specialized litigation boutique law firms working on complex litigation, investigation, and/or arbitration matters. The Paralegal may be based out of the Firm's Palo Alto or San Francisco office.Duties & Responsibilities:Working with paralegals and/or attorneys, perform all elements of litigation case management, including document and file management, case calendaring, discovery support, and trial prep and logistics activities.Interact with outside entities (e.g. courts, government agencies, expert witnesses, corporations, vendors and other law firms) to coordinate activities as needed in support of assigned cases.Draft, review, and/or analyze routine legal documents as requested by attorneys; conduct legal research under attorney supervision.Create and maintain effective working relationships with others to facilitate a positive and productive work environment.Continuously refining, developing, and expanding skills in anticipation of changes in the work environment or profession.Adhere to Firm policies, practices, and priorities; and perform other duties as requested by Firm management. -Requirements: -At least 2 years work experience as a Litigation Paralegal in an Amlaw 100 firm or suitable specialized litigation or other dispute resolution firm.Experience with all stages of litigation, including use of current e-discovery database tools, modern e-filing practices, and trial preparation activities required; experience working at trial or arbitration proceedings strongly preferred.Ability to communicate (both written and verbal) with individuals at all levels of the firm in an appropriate and professional manner; strong service orientation, sense of accountability and attention to detail.Ability to take ownership of projects and proactively handle all paralegal responsibilities without prompting from administration or attorneys.Demonstrated ability to coordinate and perform multiple tasks simultaneously; work equally well as part of a team in both a leadership and subordinate role; and excellent organizational skills.Ability to work well under deadlines and pressure typical of complex modern litigation, investigation, and arbitration matters.Proficient with Microsoft Office software products including Word, Excel, Outlook and PowerPoint.Proficient with cite-checking, Bluebook rules, and California Style Manual preferred.Available for overtime work and reasonable business travel as needed. -BS/BA from an accredited college or university highly preferred. -Paralegal certificate preferred.Covington & Burling LLP is an equal opportunity employer and does not discriminate in any aspect of employment, including hiring, salary, promotion, discipline, termination, and benefits, on the basis of race, color, ethnicity, religion, national origin, gender, gender identity or expression, age, marital status, sexual orientation, family responsibility, disability (including physical handicap), or any other improper criterion. - - ()
          

Legal: Senior Real Estate Litigation Attorney - San Diego, California

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JOIN A FIRM WHERE YOU CAN HAVE IT ALL - WORK/LIFE INTEGRATION IN ACTION. Goode, Hemme & Barger is an established boutique law firm that offers the flexibility of schedule and rewarding work. We provide our team with a reasonable workload, flexible schedules, and attainable billable hour requirements - while expecting a dedicated effort. RICH HISTORY OF SUCCESS & SUPPORT Our firm has a rich history with a strong track record of success. The partners are committed to supporting their team in business development, learning opportunities, and provides the freedom to work independently with a foundation of trust to perform your work. TEAM FIRST / WORK-FAMILY CULTURE If you are looking for a place to focus, or grow in ways you have not yet imagined, and belong to a dynamic team - look no further. Our firm offers a work-family culture with a deep commitment to excellence lead by an enjoyable and collaborative team. The leadership team cares about the well-being of our team members through life's ups and downs. This innovative yet dedicated law firm is inclusive, approachable, collaborative, and caring. Our law firm offers an environment where each team member can feel a sense of independence and belonging. PASSION FOR LAW & DEDICATION TO CLIENT SERVICE Goode, Hemme & Barger's mission is to provide outstanding service, exceptional results, and a more compassionate voice for our client's legal needs. Our skilled attorneys and team members understand that the prompt resolution of a dispute is the goal for our clients. But, if litigation is needed, our team has the skills and experience to go above and beyond for our clients. DEDICATED TO OUR COMMUNITY Our firm is passionately engaged in San Diego through offering legal pro bono work, charitable giving, volunteer work, and board leadership. We are seeking individuals who are driven to impact our community not just through excellent legal representation but by giving back to all stakeholders in our community in a dedicated and meaningful way. Are you an experienced Real Estate and/or Business Litigator that is looking for a long-term career opportunity? Apply now to learn more. Our firm has over 34 years of history serving the Southern California area, and we are now expanding and preparing for the long-term future. We are actively seeking a Real Estate and/or Business Litigator with 10 years of experience. For top candidates that have a portable book of business, we offer an expedited track to partnership. Responsibilities & Duties: Litigation duties: initial case review, drafting pleadings and motions, propounding and responding to discovery, arguing motions, preparing matters for trial, and participating in mediations. Client needs - Gathering evidence, communicating with clients, and ensuring prompt and respectful communications, maintaining communication, and exceeding client expectations. Firm citizenship: respectful communications at all times, consistency and reliability, great attitude and energy, excellent demeanor when under pressure, team player, contributor. Handle a variety of matters in a high volume, fast-paced office. The ideal candidate must be able to manage files independently, multi-task, and manage the workload as well as client expectations. Trial experience preferred. The candidate will directly deal with clients and potential clients. Experience & Qualifications: Admission to the CA bar is required. 8 years' experience in Real Estate and/or Business Litigation highly preferred. Previous Litigation experience required. Comfortable working independently or with a team. Required areas of expertise - Real Estate Litigation and/or Business Litigation Areas of expertise (Not required) - Employment Litigation, Real Estate Transaction, Probate. The ideal attorney will have an existing client base and a minimum of eight years of experience. Compensation & Benefits: This position includes a complete benefits package (health, dental, 401K, bar dues, cell allowance, CLE). Salary, incentives, and bonuses will be commensurate with experience, qualification, and ability. Please email resume and writing sample. The annual compensation includes a base salary that can be supplemented with a percentage of collections from matters originating from your efforts. We are very interested in candidates that have a current portable book of business with bandwidth to take on more work. ()
          

Other: Calendar/Docket Clerk - Newport Beach, California

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DescriptionOur client is one of the top trial firms in the nation. They are seeking a docketing clerk to assist their Newport Beach office ASAP! Successful candidates will have recent experience with CompuLaw and familiarity with litigation deadlines. This position will review legal documents to calculate, record and disseminate important events and deadlines pursuant to applicable rules and practices (state and federal).FOR IMMEDIATE CONSIDERATION, please send your resume in WORD format and qualifications to Natalie.Tran@RobertHalfLegal.com AND in the subject of your email, please include the title of the position you are applying for: Docketing ClerkResponsibilities: Calendar relevant event dates, deadlines and reminders via CompuLaw Interpret and advise on applicable civil rules of procedure, local rules and practices in State and Federal courts with respect to calendaring Respond to written or verbal requests/inquiries from attorneys and staff regarding calendared events and deadlines, pleadings, and court procedures Communicate effectively in writing and orally with all levels of the firm and courtsRequirements: Recent exposure to CompuLaw Familiarity with litigation deadlines (state and federal) Strong knowledge of legal docket calendaring and accurate at data entry Ability to organize and prioritize a high volume workload, and manage competing prioritiesRequirementsFOR IMMEDIATE CONSIDERATION, please send your resume in WORD format and qualifications to Natalie.Tran@RobertHalfLegal.com AND in the subject of your email, please include the title of the position you are applying for: Docketing ClerkLocated in major North American and global markets, Robert Half Legal is the premier provider of legal staffing and consulting solutions on a full-time, project, and temporary basis, serving both law firms and corporate legal departments. We also provide project and eDiscovery teams and workspace for a wide range of initiatives, including litigation support, mergers and acquisitions and document review matters. Our dedicated teams' industry experience allows us to quickly match skilled legal professionals with the best available jobs. We offer challenging opportunities, competitive compensation and benefits, and skills-enhancement training.Call your local Robert Half Legal office at 888-490-5592 to discover more about this position. Apply for this job now or contact our branch office for additional information.All applicants applying for U.S. job openings must be authorized to work in the United States. All applicants applying for Canadian job openings must be authorized to work in Canada.Robert Half is not a law firm and does not provide legal representation. 2019 Robert Half Legal. An Equal Opportunity Employer M/F/Disability/Veterans.By clicking 'Apply Now' you are agreeing to Robert Half Terms of Use.Salary: DOELocation: Newport Beach, CADate Posted: November 22, 2019Employment Type: TemporaryJob Reference: 00350-0011260223Staffing Area: Legal ()
          

VirtualCytometry – Webserver for the Study of Immune Cell Differentiation using single-cell RNA sequencing data

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VirtualCytometry :: DESCRIPTION VirtualCytometry is a webserver that provides computational platform for the study of immune cell differentiation using scRNA-seq data by enabling identification and validation of genes involved in immune cell differentiations via ‘Discovery Module’ and ‘Hypothesis Test Module’ respectively. ::DEVELOPER Network Biomedicine Laboratory at Yonsei University, Korea :: SCREENSHOTS N/A :: REQUIREMENTS Web browser … Continue reading VirtualCytometry – Webserver for the Study of Immune Cell Differentiation using single-cell RNA sequencing data
          

IMS Discovery - Week 11

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This week we've consolidated all the detail from our LDG funding bid, tender requirements, YouTube show & tell, blog posts, Slack channel and inception week into a distilled Discovery Plan and Stakeholder Map.


          

S2E12: Baby Doe - The Murder of Bella Bond

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Writer: Fiona Guy In 2015 the discovery of a child’s body on a secluded area of beach sparked a quest to find the child’s real identity and who was responsible for her death. The death of a young child is a tragic event. The death of a young child due to murder is an event that lights a fire under all involved, to seek the truth and achieve justice for that child and life they have lost. Justice is not a straight-forward concept in this case as you will hear. I will leave it up to you listener to decide for yourself, if justice, in this case, was truly achieved. CW: Child Death, Drug Abuse Sources: See Website Want to contribute even more to End the Backlog? Use promo code GIVEBACK for any of the shows below to get the first month to their Premium channel, FREE! All proceeds made will be donated.  Out of the Shadows: https://www.himalaya.com/Out  The Box of Oddities: https://www.himalaya.com/BOO Crime Salad: https://www.himalaya.com/crimesalad Invisible Choir: https://www.himalaya.com/choir True Crime Historian: https://www.himalaya.com/TrueCrime
          

'Diamond in a Diamond' Joins Alrosa's Collection of Rare Finds... and Is Not for Sale

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Russia’s Alrosa diamond mining company announced Thursday that the curious "diamond in a diamond" revealed on social media in early September has been added to its collection of rare finds — and is not for sale.



In early September, Alrosa surprised its Instagram followers with a video that seemed to show a tiny rough diamond moving freely in the cavity of a larger one. The caption read, “A diamond in a diamond? We couldn’t help but share this very special find with you.”

At the time, Alrosa wasn’t quite sure what to make of the phenomenon. Nobody at the mining company had ever seen anything like it. Five weeks later, Alrosa scientists confirmed that both the host and smaller crystal were diamonds.

They named the double-diamond “Matryoshka” because its strange configuration is reminiscent of the popular Russian nesting dolls. The specimen, which weighs only 0.62 carats, was discovered in Yakutia at Alrosa's Nyurba mining and processing division.

Matryoshka joins Alrosa's ever-growing collection of diamond wonders. These include crystals that resemble a soccer ball, a Valentine heart, a skull and a fish.

Interestingly, some of Alrosa's most unusually shaped diamonds have come to light at the most opportune times.



For instance, an Alrosa discovery in July of 2018 had us wondering out loud if Mother Nature was a World Cup soccer fan. Just three days prior to the Russian national soccer team’s exciting quarterfinal match against Croatia in the 2018 FIFA World Cup™, Alrosa discovered a diamond that looks amazingly like a soccer ball.



In February of 2019, Alrosa revealed a 65.7-carat rough diamond that had an uncanny resemblance to a Valentine heart.

“Diamonds of a distinctive shape that resemble some object or symbol are extremely rare in nature," Alrosa's deputy CEO Evgeny Agureev said at the time. "Most rough diamonds are octahedron-shaped or do not have a particular shape at all. The appearance of a heart-shaped rough diamond, especially on the eve of Valentine's Day, seems to be a symbolic gift of nature not only to our company, but also to all loving couples.”



Alrosa noted that a 24-carat, skull-shaped stone was unearthed prior to Halloween in 2018.



In August of 2019, the company posted to Instagram a photo of a rough stone resembling a fish. It had been discovered back in 2002, and was revisited to help promote the firm's ecology efforts, which include releasing hundreds of thousands of fish into the rivers near its mining operation in Yakutia.

Credits: Diamond images courtesy of Alrosa Diamonds and via Alrosa/Instagram. Soccer ball image by Pumbaa80 (Self-published work by Pumbaa80) [GFDL or CC BY-SA 3.0 ], via Wikimedia Commons.

          

24.11.2019: Herbstfarben

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Bild Titel

Herbstfarben


Sonntag nahezu ganz verschlafen. Erkältung hat wieder angezogen. Fühle mich fett und aufgedunsen. Viel Star Trek Discovery geguckt.


          

Crystal Mountain Resort opens Friday; other ski areas could soon follow

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The blast of snow that hammered the Cascades earlier this week has snowboarders and skiers looking past Thanksgiving and to the slopes. They may not have to wait much longer. Crystal Mountain Resort has gotten — and created — enough snow to open its Discovery Meadow area this Friday for the weekend. It will run 9 a.m. […]
          

10 things I loved about November; Starbucks, Mac Cosmetics and more

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Each month, WPP's chief client officer Lindsay Pattison will share her favourite client developments in the world of creativity and technology. Here she takes a look back at what caught her eye in October.

1. Another month, another excellent podcast. This time it’s Martin Renaud, CMO Mondelēz, talking all things mindful snacking, streamlining the agency model and that holy trinity of data, media and creative. Oh, and being absolutely obsessed with building brands on strong, strategic foundations.

2. Starbuck’s is piloting a ‘micro-café’ in NYC bereft of the usual coffee shop hallmarks: menu boards, comfy chairs and long queues at the cash register. Instead, the space is designed for customers to order via phone (I imagine the Starbucks app will get a whole lot of new users) and then pick up their order on arrival. The space is only 28 square metres (300 square feet) - a smart move to keep sales moving but cut down on rent and staff costs.

3. Unilever has successfully finished trialling ethical ad tech where people who watch video ads online can pick a charity to donate the 50% of the ad revenue to. First up was Knorr and Lynx on traditional advertising sites (powered by the technology Good Loop), now it’s Dove on Instagram stories. Watch out for the swipe up to donate to either UN Women or the local Dove Self-Esteem Project.

4. Mac Cosmetics has taken the intersection of beauty, tech and physical retail to the next level with the Shanghai Experience Centre. With customers invited to use WeChat instore to augment the experience, virtual makeup mirrors that allow you to try 18 different lipstick colours in 30 seconds, and social reviews available at each product station - this is a space that seamlessly blends product discovery, social engagement and purchase.

5. This is so neat and incredibly powerful. Using old black & white war footage juxtaposed with familiar icons and sounds from the gaming world, gamers are being asked to #PauseToRemember on 11 November, 11am (Remembrance Day). The message? War is not a game.

6. Livestream shopping generated $4.4bn in Chinese sales in 2018. One of H&M’s brands, Monki, has embraced it with a recent livestream, filming their editor-in-chief and chief buyer discussing trends and inspecting Monki products live to 19 markets. It was hosted on Monki’s website instead of a third-party app, which meant customers could interact with their host and shop the products.

7. It feels like the beverage arena is as hotly contested as the streaming one right now. That arena has a new player in the form of Coca-Cola’s new flavoured seltzer water brand - AHA. It's Coca-Cola’s first new drink in more than a decade, and it’s well worth the wait. I love the packaging, the crisp-sounding flavours (think lime & watermelon, citrus & green tea) and the splash of caffeine is right up my street.

8. Like many of you reading this column, I’ve long been a fan of Whitney Wolfe Herd, founder and CEO of Bumble. Well, former CEO of Bumble – because she’s now moved up to CEO of MagicLab, Bumble (and Badoo’s) parent company, recently valued at $3bn thanks to Blackstone taking a majority stake.

9. I’ve always thought C-suite titles are a good reflection of industry trends. Today we have chief people officers, chief ethics officers, and at Google, a chief decision scientist. What is a chief decision scientist? Cassie Kozyrkov uses applied data science, AI and behavioural science to create better tools and products - a discipline that she calls decision intelligence. In real life, it also means letting “well thought-out projects flourish, as well as identifying ill-advised projects so these can be shut down before they begin.”

10. And to finish, Prada and Adidas have confirmed a long-term collaboration, with the first products dropping this December. The projects aim? ‘Investigate the realms of heritage, technology and innovation - and to challenge conventional wisdom through unexpected strategies.’ One for all sneaker-heads to keep their eye on ahead of Christmas…


          

The agency noted that methane levels can fluctuate from day to

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mindy kaling dishes about why she hates being a bridesmaid

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Carobon Fibre Style Plastique ABS Cadre de décoration Panneau de navigation GPS pour Discovery Sport Accessoires Auto

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Library Services Technician

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The Library Technician carries out cataloging duties for the NTC Library and is responsible for the administration of the Integrated Library System (ILS), the discovery service, and inventory of library collections.  In addition this position provides reference services for faculty and students at all NTC campuses including online learners, maintains online databases, compiles Library statistical […]
          

Max & Murphy Podcast: Debating Major Criminal Justice Reforms Taking Effect in January

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Max & Murphy Podcast: Debating Major Criminal Justice Reforms Taking Effect in January admin Sun, 12/01/2019 - 18:11
Channels

          

A spot on Earth with no life discovered

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It becomes impossible to imagine Earth with no life on it; but a recent discovery has shocked everyone with a place on the planet that has no life.
          

A Discovery of Witches - Magic is desire made real by DragoninadressStore

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7.99 GBP

A Discovery of Witches inspired - Magic is desire made real

Ceramic Tea/Coffee Mug, Bone China Mug or Stainless Steel Travel Mug

Sublimation printed and heat pressed.

White mug, Coloured images and black text

Available in 11oz UK standard mug size or larger 15oz ceramic mug, 10oz Bone China Mug and 14oz travel mug.

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Travel Mug is Dishwasher safe but for best results, hand wash.

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99 Discovery Wiring Diagrams

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99 Discovery Wiring Diagrams
          

Pharmacy Technician | Vanderbilt Health

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Nashville, Tennessee, Description Day Shift - Pharmacy Technician Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating a
          

How to use an IDX app in your leads workflow

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IDX apps are a powerful tool for your business. They can help engage potential and existing clients, improve brand loyalty, and get people addicted to your services. But to get the most benefit, you need to know when to promote your app and how to use it within your existing workflow. Timing is everything. Typical journey of buyers & sellers First, let's talk real quick about the basic digital journey that almost every buyer and seller takes: 1. Search online When someone decides to buy or sell a house, they tend to start in one of two places: referrals or web searches. In either scenario, the person is trying to find more information about the real estate process. People who don't want to start with an agent will search terms like "Vancouver real estate" in search engines to see what comes up. Likewise, we know from our real estate market research that buyers and sellers vet real estate agents online as the next step after they've received a referral. This means that regardless of whether someone starts their search on the internet or through friends, they're going to be browsing the web next. 2. Website discovery Once a potential client finds your website, they're going to look around. They will probably check out your home page, click on a few listings, and hover on your navigation. If the buyer or seller likes what they see, they'll explore further. It typically goes one of two ways from here. Either the user registers on the site and becomes a lead, triggering your lead follow-up process. Or they don't find what they're looking for and leave the site, likely forever. Here's where your app first comes into play. If you're one of the few Realtors who is differentiating themselves with an app, you can give your users a third option: download and install your app. Realtors should use their websites to promote their apps—especially to people on mobile devices. Apps create a better user experience and, if potential buyers download your app, the likelihood they'll become clients is much stronger. 3. App discovery If you managed to successfully get your website visitors onto your app, give yourself a high five. More than 70 of active app users on REW-built apps visit the site at least three times per week. That's a pretty powerful statistic because it indicates that users are hooked on the apps. Getting people to install your app is the single biggest hurdle in the entire process but it's a critical step for your app's success. Do everything you can to get people to try your app Once they do, you may very well have new customers for life. 4. App engagement This is where the magic starts to happen. Once someone downloads your app, they're going to try it out. If they like what they see and find what they're looking for, they're going to be hooked. The best part about real estate apps is they're focused on exactly what buyers want: homes. Push notifications and alerts remind visitors to come back to the app, and—if your app is through REW—all the homes viewed in the app will be recorded in your CRM. How to naturally promote your app If anyone contacts you or indicates they are searching for homes in any manner, the next step should be to recommend your app. Send them your link and let them know how the app will help them achieve their goals. But just in case they don't contact you, you'll want to make the app an obvious option on your website too. There's a very limited window of opportunity to get users on your app and your goal is to make it as easy as possible to find and download your app. Here are a few ways you can promote your app through your website: Intercept ads - particularly those that detect mobile devices Download buttons in visible locations on the website On the "thank you" page of any form In the auto-email received after a form submission Using app data to convert leads into clients The final piece of the app puzzle is converting those app leads into actual clients. If you use an app that automatically syncs data with your lead management platform, like our branded IDX apps do with REW CRM, you can use your existing action plans and follow-up procedures. Within the CRM, you'll be able to see exactly which properties your leads interacted with, as well as their saved searches and historical activity. Use this information to get in touch, foster meaningful connections and deliver additional info that's of value. Even just a, "Hey, I saw you looking at 246 Chesterman on my app. It's a gorgeous property. Want to check it out?" will go a long way in building new relationships. At the end of the day, your app is another way to help people find information and get clients engaged with your brand. In return, their data will provide you with invaluable insights that you can couple with your follow-up strategy and use to transform those leads into clients.
          

What protects killer immune cells from harming themselves?

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White blood cells, which release a toxic potion of proteins to kill cancerous and virus-infected cells, are protected from any harm by the physical properties of their cell envelopes, find scientists. Until now, it has been a mystery to scientists how these white blood cells -- called cytotoxic lymphocytes -- avoid being killed by their own actions and the discovery could help explain why some tumors are more resistant than others to recently developed cancer immunotherapies.
          

Ahab, Jezebel, and Naboth

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Series: N/A

Service: Sun PM

Type: Sermon

Speaker: Steve Sebree

Ahab and Jezebel's conflict with the Lord, his prophet Elijah, and the vineyard owner Naboth are notorious. Steve explains some of the issues leading up to this conflict, as well as the conflict itself. He brings out the insight that Naboth's vineyard would have been an important addition to Ahab's palace, as Ahab and Jezebel served hundreds in their idolatrous feasts. Steve also brings the most recent archaeological findings of Jezreel and the fantastic discovery of what seems to have been Ahab and Jezebel's palace as well as the winepress of Naboth!
          

Sheffield #Discovery-II-D-12, 508x915x406mm, Renishaw MH20i/TP20, PC-DMIS, 2015 MEASURING MACHINES (Including Coordinate Measuring Machines CMM's)

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MEASURING MACHINES (Including Coordinate Measuring Machines CMM's)
CMMXYZ, Mississauga, ON 800-606-9266 (Email: sales@cmmxyz.com) Jim Jewell
          

Chamber Celebrates 100th Business

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For additional information contact:

Mara Kuhn

Communications Manager

501.321.1700

mara.kuhn@growinghotsprings.com

Chamber Celebrates 100th Business to Open in Downtown Hot Springs since the 2014 Majestic Hotel Fire

(Hot Springs, AR)  May 3, 2018 – On Thursday, the Greater Hot Springs Chamber of Commerce celebrated the 100th new business to open in downtown Hot Springs since the 2014 Majestic Hotel fire with a special ribbon cutting at Vault, the highly anticipated new downtown restaurant.

“One hundred new businesses opening in four years is an incredible milestone. It’s real proof of a very strong economy in downtown Hot Springs,” said Cole McCaskill, Vice President of Economic Development with the Hot Springs Metro Partnership.

“Even more impressive is that of the 100 new businesses, 90 of them are still open and 66 of them were net-new additions to downtown, meaning they occupied and opened in a retail space that was previously vacant as opposed to replacing a recently closed business.”


Cole McCaskill, Vice President of Economic Development with the Hot Springs Metro Partnership, second left, speaks as U.S. Senator John Boozman, left, Congressman Bruce Westerman, and Gary Troutman, President and CEO of the Hot Springs Metro Partnership and Greater Hot Springs Chamber of Commerce look on.

In addition to 100 new businesses since the fire, Downtown Hot Springs has seen 82 commercial property sales and more than $80 million in investment. The Majestic Hotel was one of Hot Springs’ oldest structures. It unfortunately that became dormant and fell into disrepair before catching fire in February 2014.

The loss of one of Hot Springs’ historic and iconic buildings mobilized city and business leaders into action to revitalize and preserve the downtown area. Downtown Hot Springs, “America’s First Resort,” is famous nationwide for its history and culture. It is important to the people of Hot Springs to see this area flourish.

In the weeks following the fire, civic groups formed the “Downtown Game Plan Task Force” comprised of community leaders and downtown stakeholders that sought to prevent future tragedies like the fire and to improve the course of downtown which had suffered from a lack of investment for several decades.

That group met publicly and privately for four months and ultimately released a set of recommendations for the progress of downtown. The HSMP adopted those recommendations as a strategy and hired McCaskill as downtown development director in June 2014.

Each year since the fire, downtown has experienced subsequent rising investment levels.

In 2015, downtown saw the nearly year-long master planning process from ideation to completion with the facilitation by Thomas P. Miller and Associates from Indianapolis.

That strategic planning process sought input from downtown business owners, Garland County residents and visitors for what they’d like to see in downtown. The Downtown Redevelopment Guide was published and its goals and strategies were adopted to provide a framework for growth and development for downtown by the City of Hot Springs and the HSMP.

The Chamber and HSMP look forward to future growth and expansion in the downtown area.

The 100 New Businesses Opened Downtown Since Majestic Fire:

1.         Kilwins Chocolates

2.         Kollective Coffee+Tea

3.         Wolfheart Gallery

4.         All Things Natural

5.         Render Creative Group

6.         Henderson State University- Hot Springs

7.         Copper Penny Pub

8.         Oxy-Zen

9.         Mountain’s Edge (significant remodel and reopening)

10.       Bathhouse Row Winery

11.       Tropical Winery

12.       Deluca’s Pizza

13.       Air FX Heat & Air

14.       Evil-O Olive Oils

15.       Café 135

16.       4D Adventure

17.       State & Pride Provisions Co.

18.       Red Light Roastery

19.       KUHS Community Radio

20.       Mountain Valley Armory

21.       Red Sunflower Boutique

22.       Hotel Hot Springs

23.       Rock Paper Scissors Salon

24.       Dakotas Hair Designs

25.       Vina Morita (move and expansion)

26.       Gr8 Escapes Arkansas

27.       Zoe’s In The District

28.       Gehrki Commercial Real Estate

29.       Dapper & Debonair

30.       Rocket Fizz

31.       The Civil War Museum West

32.       Tosha Kitchen

33.       Escape Hot Springs

34.       A Narrow Escape

35.       Magic Springs Retail Store

36.       J.J.’s Peddie Cabs

37.       Quarters Café

38.       Brick City Pizza

39.       Prohibition Press

40.       Park Avenue Coin Shop

41.       Hot Springs Village Discovery Center

42.       Gypsy Girl

43.       Craft Beer Cellar

44.       Kringles in the Park

45.       Maharaja Boutique

46.       Galaxy Connection

47.       Spa City Cycling

48.       ESQ. Realty Group

49.       Crow Law Firm

50.       Metaphysical Connection

51.       The Waters Hotel

52.       The Avenue

53.       Blush Boutique

54.       Spa Souvenirs

55.       Pour Some Sugar on Me Sweet Shoppe

56.       Downtowner Marketplace

57.       Direct Insurance

58.       Revelation Teens

59.       Whittington Gallery

60.       Mountain Valley Armory (new construction & expansion)

61.       Ambrosia Bakery

62.       State & Pride Provisions Co. (Doubled in Size)

63.       A Bite of Hot Springs

64.       Riley Art Glass Studio

65.       Beef Jerky Outlet

66.       Odie & Tilly’s Boutique

67.       Park Avenue Food Court/ Its Gud Fud

68.       Dame Fortune’s Cottage Court

69.       Thai-Me and Argentinian Coffee

70.       Legoria’s Rhythm and Rocks Jazz Bistro

71.       Plum & Pretty Boutique

72.       Dogs on the Run- Hot Dog Vendor- Arlington Park

73.       The Loft Salon & Spa

74.       NU2U

75.       Wills Cinnamon Shop

76.       Roanoke Church Whittington

77.       Lox Salon

78.       Home Instead

79.       Jack Knife Barbershop

80.       Next Gen Tie-dyes & Apparel

81.       TLI Print- (Property Acquisition, Renovation and Expansion)

82.       Mirror, Mirror Salon

83.       Belle of Hot Springs Retail Store

84.       Bubba Brews Spa City Taproom

85.       Maxwell Blade’s Malco

86.       Oddities Museum

87.       Culinary District Cafe

88.       Handmade Holiday Shop

89.       SQZBX

90.       Park Avenue Parking Lot

91.       TRex Fun Spot (new construction and expansion)

92.       Grateful Head Pizza

93.       Urban Living & Development

94.       Core Public House

95.       Hot Springs Advertising

96.       Healthy Connections Administration Office

97.       Majestic Bakery & Café

98.       ParadICE Cream

99.       Taylor’s Lunchbox

100.    Vault


 

 

The Greater Hot Springs Chamber of Commerce is Hot Springs’ leading advocate and champion for business.

For further information, contact Mara Kuhn at 501.321.1700 or mara.kuhn@growinghotsprings.com

 

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Pharmacy Technician-2nd Shift | Vanderbilt Health

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Nashville, Tennessee, Description Pharmacy Technician III Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and o
          

Korrigans

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Krakon Games a lancé une campagne pour financer une nouvelle armée de Nains du chaos en 28mm, les Korrigans,  ainsi que quelques renforts pour les armées Gnomes.
Vous trouverez uniquement de l'infanterie en dehors d'un gnome sur sa limace géante.
Plus que 9 jours pour les enrôler.
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Krakon Games has launched a campaign to fund a new army of 28mm chaos Dwarves, the Korrigans, as well as some reinforcements for the Gnome armies.
You will find only infantry outside a gnome on its giant slug.
Only 9 days to enlist them.



          

The Trapdoor Inn

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Voilà une campagne dont l'objectif était de 11$ et il est bien sûr atteint.
Cette mini-campagne a encore 4 jours à vivre et elle vous propose des personnages fantasy au sein d'un diorama qui représente une auberge avec une trappe au sol.
Les différents pledges vous permettent d'obtenir des productions précédentes et bien sûr celles de cette campagne en fichiers STL et OBJ.
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This is a campaign with a goal of $ 11 and of course it has been achieved.  
This mini-campaign still has 4 days to live and it offers you fantasy characters in a diorama that represents an inn with a hatch on the ground.
The different pledges allow you to obtain the previous productions and of course those of this campaign in STL and OBJ files.



          

Servants of chaos II : les Nains

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Ridgeback Games a lancé la suite de la campagne Servants of Chaos. Cette fois des nains mais aussi quelques orcs et humains sont disponibles en 32 et en 75mm.
La campagne est financée à cinq jours de la fin.
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Ridgeback Games launched the sequel to the Servants of Chaos campaign. This time dwarves but also some orcs and humans are available in 32 and 75mm.
The campaign is funded five days from the end.






          

Mud brick starter

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Ils sont pré-assemblés et pré-peints en 28mm, Fogou Models nous propose des bâtiments en briques de boue pour des combats se situant sous d'autres latitudes.
A 13 jours de la fin, la campagne est très largement financée.
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They are pre-assembled and pre-painted in 28mm, Fogou Models offers us mud brick buildings for fights located in other latitudes.
13 days from the end, the campaign is largely funded.



          

Create more demand for local gas — ENI Ghana MD

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The Managing Director of ENI Ghana, Mr Roberto Daniele, has said the country needs to cut its importation of gas from external sources and make use of what is produced domestically.

He said gas produced collectively from the Jubilee, Tweneboa Nnyera and Ntomme (TEN) and the Sankofa Gye Nyame (SGN) fields was enough to meet local demand, adding that as the situation stood now, excess gas was still being re-injected into the fields because of processing capacity constraint.

ENI Ghana is the operator of the SGN fields which has the capacity to produce about a 180 million standard cubic feet of gas (mscf) per day, while combined gas production from the Jubilee and TEN fields is estimated at 300mscf per day.

Speaking in an interview with the Daily Graphic at the 2019 Ghana Gas Forum in Accra last Wednesday, Mr Daniele reiterated that the country had no reason to import gas because domestic gas sources were enough if fully optimised.

“There is no need to import additional gas. We have extra gas available today so there is no need for importation.

“We need to create the demand for the available gas. We need to optimise our resources and not bring in resources from outside,” he said after addressing a session at the forum.

Mr Daniele explained that it was time to make use of the domestic gas resources by creating enough demand for it to remain attractive in the industry, as well as continued investments in the upstream industry which would influence prices, bring more stability and competition.

Prospects

He explained that there was more potential to increase gas production in Ghana because operators continued to identify new opportunities for exploration.

ENI, he said, recently acquired a new block and gave an indication that exploration activity on it would be intensive from next year.

“We have done a discovery in block four this year, so we will have an appraisal well coming next year for us to complete the exploration activity,” he said.

He explained that more operators coming into the oil and gas sector in Ghana was not a competition, instead it afforded a collective opportunity to exploit the resources for the benefit of all players.

“We are not competing. In fact, we are very happy if other partners will come into the country. It is positive for the country and it will create the right volume for the country to be competitive and everyone will benefit,” he said.

He noted that although the prospects were huge, it would be too speculative to tell how much the new field would add on to ENI’s production figures in Ghana, explaining that more appraisal wells would be drilled to ascertain the levels before coming out with figures.

“For the existing wells, we can already produce more than we are doing.

We can produce at least 40 per cent more than what we are doing now.

This means there is no need to import gas,” he said.

CEO Interactive Session

As part of the two-day 2019 Ghana Gas Forum, there was a CEOs interactive session that brought together players to share perspectives on the specific challenges that various companies along the gas-to-power value chain faced, and the level of confidence that surrounded government interventions aimed at resolving weaknesses in the value chain.

The two-day conference, which was organised by The Gas Consortium (TGC), was on the theme, “Promoting dynamic policymaking towards the optimisation of regional gas resources”

The General Manager, Commercial Operations at the Ghana National Gas Company, Mr Francis Boateng, who was also part of the session, explained that there were a lot of demand opportunities for gas usage in the country, especially for industries.

He said a second gas processing plant with a proposed capacity of 150mscf per day was also in the offing to enable the country to process more of its gas.


          

Library Services Technician

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The Library Technician carries out cataloging duties for the NTC Library and is responsible for the administration of the Integrated Library System (ILS), the discovery service, and inventory of library collections.  In addition this position provides reference services for faculty and students at all NTC campuses including online learners, maintains online databases, compiles Library statistical […]
          

Social Worker PRN - Vanderbilt Psychiatric Hospital | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient ca
          

Legal: Corporate Litigation Paralegal - Oklahoma City, Oklahoma

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INCEED is currently partnered with a local law firm who is looking to add a Litigation Paralegal to their team. The ideal candidate would have over 4 years of experience working within corporate litigation and would have experience billing out to clients. This person would need to be highly organized, detail oriented and professional, due to the high-end client nature of the business. -Please apply if you are interested in the ability to use your experience and background to help a great company thrive! Responsibilities: Conduct pre-claim investigation, legal research and initial case assessments Draft pleadings, motions and appellate documents and file them with the court Perform administrative duties (calendar hearings and deadlines, organize case files, manage logistics etc.) Billing out to clients Maintain pleadings and discovery indexes Organize exhibits, documents, evidence, briefs and appendices Aid attorneys with interrogatories and other discovery requests Gather relevant information from a variety of sources Liaise between trial teams and internal/external third parties Help with voir dire, jury selection and witness preparation Provide assistance with case settlements Education and Experience Requirements: 4+ years related experience with a background in corporate litigation Proven working experience as a litigation paralegal Applicable knowledge of motions, discovery, evidence, litigation documentation, court rules and procedures, practices etc. Highly organized with ability to juggle multiple deadlines in a fast-paced environment Strong writing and communication skills along with attention to detail Extensive computer and database expertise Paralegal associate's degree or other relevant certification preferred Must be able to take and pass a background check and drug screening - ()
          

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Registered Nurse 2 ~ Hepatology Nurse | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patien
          

Registered Nurse 2 ~ ASAP Clinic | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient
          

Registered Nurse PRN (As Needed) ~ Pulmonary Clinic | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient care, VUMC is
          

Registered Nurse (RN) (PRN)(As Needed) - Asthma, Sinus, Allergy Program Clinic (ASAP) | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient care, VUMC is
          

Want to be more creative? Take a hike.

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I have a confession, Reader: sometimes I lie to myself. Sometimes, I promise myself that I'll get work done, and then it's somehow 4 p.m. and the only meaningful thing I've done is…go for a really long walk.

I tell myself that taking long walks is a crucial part of my creative process. I simply cannot write without taking a walk. I've believed this pretty much forever.

But is there any scientific evidence for it? Or is it just a way of justifying my horrible procrastination?

Walking lifestyles of the (creatively) rich and famous

An unfortunate photo of New Jersey

Before we get into the empirical evidence for—or against—walking as a creativity booster, it's worth noting that there's fairly strong anecdotal evidence for it. Plenty of famous creative minds have credited walking as an important part of their process.

Beethoven, for example, loved to take long walks, often through the countryside when he was composing. In fact, it's widely accepted that these walks helped inspire his Symphony No. 6—which is also known as the Pastoral Symphony because of how it evokes the rural landscapes through which he walked.

Composers Mahler and Benjamin Britten were similarly enamored of walks. “[My afternoon walks are] where I plan out what I’m going to write in the next period at my desk," said Britten in a BBC interview with Lord Harewood, later featured in the book Britten on Music. For countless musicians, writers, and artists, a long walk is a key part of a productive daily routine.

But it's not just artists who have historically used walking as a thinking aid; plenty of thinkers and business people have too. Walter Isaacson's comprehensive biography of Steve Jobs reveals that the Apple co-founder was especially fond of walking. Following in his footsteps (pun fully intended), Facebook founder Mark Zuckerberg and Twitter founder Jack Dorsey take frequent walks, with Zuckerberg even using them as his preferred mode of interview.

What is creativity, anyway?

A walk I took in Calgary, Alberta

If so many geniuses enjoy walking, they've got to be on to something, right?

Well, maybe. In order to talk about the connection between walking and creativity, we first have to define what creativity is—and how to measure it.

As Maria Konnikova points out in The New Yorker, creativity isn't just about making something new:

In the field of psychology, there’s long been a certain haziness surrounding the definition of creativity, an I-know-it-when-I-see it attitude that has eluded a precise formulation […] What, for instance, crosses your mind when you think of creativity? Well, we know that someone is creative if he produces new things or has new ideas. A choreographer, an artist, a writer, a scientist, or a mathematician with a novel discovery—these are the creatives, the people who bring something new into the world. And yet, as John Kounios, a psychologist at Drexel University […] points out, that view is wrong, or at least not entirely right. "Creativity is the process, not the product," he says.

The ways in which researchers measure creativity reflect this process-based definition. Generally, they look at something called divergent thinking, which is the ability to come up with ideas that deviate from the norm.

A popular way to measure divergent thinking is to ask study participants to play a game called Alternate Uses. In this exercise, you're asked questions like: How many ways can you think to use a tire, besides putting it on a car's wheel?

You might think up answers like "as a tire swing" or "to do Crossfit." That's divergent thinking at work.

"To see how well you did, we could count up the number of feasible uses you mentioned (fluency), the number of different types of uses (flexibility), and how uncommon your answers were (originality)," writes Thomas Ward, a psychology professor whose research focuses on creativity.

This method is how researchers at Stanford conducted a 2014 study on the link between walking and creativity:

Three of the experiments relied on a 'divergent thinking' creativity test. Divergent thinking is a thought process or method used to generate creative ideas by exploring many possible solutions. In these experiments, participants had to think of alternate uses for a given object. They were given several sets of three objects and had four minutes to come up with as many responses as possible for each set. A response was considered novel if no other participant in the group used it. Researchers also gauged whether a response was appropriate. For example, a tire could not be used as a pinkie ring.

Turns out, exercise itself is pretty useful

My neighborhood

It's well-established scientifically that aerobic exercise in general helps improve mood. For a long time, researchers have assumed that mood improvement was why people experienced enhanced creativity post-exercise.

It intuitively makes sense: exercise makes you feel better, so you're more likely to think better too.

But more recent research indicates that exercise may improve your creative thinking independent of your mood:

Analysis of variance showed a large and significant increase in positive mood after exercise and a significant decrease in positive mood after video watching. A significant increase between the creative thinking scores of the two conditions was found on the flexibility (variety of responses) measure. A multifactorial analysis of all data failed to show a significant covariance of creative thinking with the two measures of mood.

In plain English, people think more flexibly after they've exercised—and this effect is independent of mood. So while exercise may also put you in a better frame of mind, it can still improve your creativity even if it doesn't make you happier.

The intensity of the exercise also matters. A study published in Frontiers in Human Neuroscience found that, compared to resting, moderate to intense cycling resulted in poorer performance in the Alternate Uses game. These results indicate that, when it comes to improving creative thinking, more relaxed exercise might be best.

(Don't) Walk the line

My editor Justin saw some ducks once; it was alright

That's where walking comes in. The Stanford study I mentioned earlier found that walking significantly increased participants' creativity—at least when compared to doing nothing:

The overwhelming majority of the participants in these three experiments were more creative while walking than sitting, the study found. In one of those experiments, participants were tested indoors—first while sitting, then while walking on a treadmill. The creative output increased by an average of 60 percent when the person was walking.

But while walking may help you with divergent thinking, it's not particularly useful for other kinds of problem-solving. The study notes that focused thinking to find one correct answer—also known as convergent thinking—didn't improve during or after a brief walk. In fact, they performed slightly worse. So when you need to boost your convergent thinking, you might benefit more from other methods of jumpstarting your brain.

Other studies indicate that the type of walking can also determine how much of a creativity boost you experience. One such study published in Frontiers of Psychology asked participants to think up alternate uses for chopsticks after either walking in a rectangle or freely wandering around. The free walking group performed better than those who walked a rigidly defined path, scoring better on measures of fluency, flexibility, and originality.

So should I go for a walk right now?

All of this research is to say: there's probably some link between relaxed, somewhat aimless physical movement and stronger creative thinking, but no one is 100 percent sure how it works. I, for one, will stick with my walking habit.


          

Discovery.Me podstawy koloryzacji Matrix

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Jednodniowe szkolenie przeznaczone dla nowych klientów oraz fryzjerów chcących odświeżyć fundamentalną wiedzę na temat koloryzacji Matrix. PROGRAM SZKOLENIA: Wprowadzenie nowego klienta w świat koloryzacji Matrix Omówienie podstawowych zasad koloryzacji
          

Survey Results — The State of the NetSquared Community in 2019

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Who are NetSquared's members? Why do they attend? What are their technology struggles? NetSquared's annual survey of all meetup members answers these questions and more. Plus, the results help our local organizers and partners build stronger groups with better events.

We received over 250 responses to the survey, drawing from our global meetup membership.

Executive Summary

  • Most NetSquared participants come from small "startup" nonprofits with no budget and no staff. They come to us looking for practical tips and a supportive community.
  • Participants find NetSquared valuable because it helps them network with other nonprofits, learn digital skills, and find project collaborators.
  • Event attendees are unfamiliar with TechSoup's services, but less so than they used to be. ;-)

NPS Score: Would You Recommend NetSquared to a Friend?

How likely are you to recommend this meetup to a friend or colleague?

We added a Net Promoter Score (NPS) scale this year, asking "how likely are you to recommend this meetup to a friend or colleague?"

A score of "4.7" doesn't mean much without context — the interesting results will come when we run the survey again and see if the score changes. But NPS benchmarks suggest that this is a low, but still positive score.

Organization Type: What Best Describes Your Organization?

What Best Describes Your Organization?

We asked people to share what kind of organization they represented. The top results were "nonprofit, NGO, or religious organization" (52%); "consultancy" (14%), and the random assortment that is "other" (11%).

Comments

Nonprofits are our core audience, so it's awesome to see that over half of attendees are people working in the sector. But NetSquared groups seek to create connections between NGOs and their allies, so it's good to see strong representation from key sector players like nonprofit tech consultants and business.

What Is Your Organization's Approximate Annual Budget? (US$)

What Is Your Organization's Approximate Annual Budget? (US$)

68% of respondents have a budget under US$1,000,000 and of that 42% are working with less than $100,000 per year.

Comments

The majority of NetSquared participants are small, scrappy, "startup" nonprofits just starting to grow. We are serving the section of civil society that doesn't yet have the ability to bring in paid consultants or dedicated technology staff.

When we compare the results of this survey over previous years, the average budget size for the organizations we serve is decreasing over time as NetSquared expands into more developing countries. This is an important reminder of the limited resources of the sector, especially outside the United States.

How Many Paid Full-Time Employees Work For Your Organization?

How Many Paid Full-Time Employees Work For Your Organization?

59% of respondents have less than ten staff. 31% are entirely community-driven and have zero paid employees.

Comments

NetSquared is serving the "accidental" techie, not the dedicated IT professional or programmer. Attendees are serving multiple roles in their organization.

Who Is Primarily Responsible for Technology Decisions at Your Organization?

Who Is Primarily Responsible for Technology Decisions at Your Organization?

49% have someone helping with a formal IT background. 61% of respondents report that they are the primary technology decision-maker at their organization.

Comments

Almost half of respondents have access to experienced IT help, whether from staff, a volunteer, or consultant. The rest are making do with "accidental techies". Very few organizations are leveraging consultants or external IT staff, probably because they are too small to afford external assistance.

What Is Your Role At Your Organization?

What is Your Role at your organization?

We asked respondents to select up to three roles they play in their organization. The top responses were:

  • Executive, Management, Director (41% — ⬆️ 12% compared to previous survey)
  • IT and Technology (32% — ⬆️ 2% compared to previous survey)
  • Marketing or Communications (21% — ⬇️️ 10% compared to previous survey)
  • Board Member (20% — ⬆️ 6% compared to previous survey)

Comments

There’s been a big jump in the percentage of nonprofit leaders attending NetSquared events. Executive Directors are no longer ignoring the significant positive impact that technology investments can make for their organizations.

TECHSOUP

The next series of questions focus on the respondent's knowledge of NetSquared's parent charity, TechSoup.

Which Techsoup Resources Do You Use?

Which TechSoup Resources do you use?

Besides the NetSquared meetups the most popular TechSoup resources are the blog (35%), product pages (33%), and webinars (31%).

Comments

Annotated version of Which Techsoup Resources Do You Use

Two and a half years ago I surveyed the NetSquared members and discovered that they weren't aware of the resources available from TechSoup. So we set to work to change that with communications to organizers and direct messaging to attendees via Meetup (which has only been possible with the rollout of Meetup Pro since the last survey). 🎉🎉AND WE’VE MADE BIG PROGRESS!🎉🎉

Is Your Nonprofit, Charity, Foundation, or Library Registered with TechSoup?

Is your organizaton registered with TechSoup?

54% of nonprofit respondents report that they have a TechSoup account (and you all should! It's free and it'll save you money!)

Comments

The percentage of TechSoup account-holders is up, but the "I don't know" option remains high at 17% (vs. 19% last time). I suspect that many of the "I don't know" nonprofits do have an account, but don't know about it because it's administered by their IT manager.

NETSQUARED MEETUPS

The next set of questions are focused on the respondent's participation in their local meetup groups.

How Did You Discover NetSquared?

How did you discover NetSquared?

Meetup is the most important tool for NetSquared discovery, with almost 50% of respondents citing it as their entry point to the community. Referrals from a friend are also important, with 25% reporting that it's a personal contact that brought them to NetSquared.

Comments

Increase in TechSoup discovery

The biggest change since the last survey is the HUGE increase in the percentage of NetSquared attendees finding the meetups via TechSoup channels. This is thanks to the increase in email marketing support from TechSoup USA.

What Are the Top Two Reasons You Participate in This Meetup?

What are the top two reasons you attend NetSquared meetups?

We asked people to select two choices from a list. The top options were:

  • Network with nonprofit staff (62%)
  • Learn digital skills (58%)
  • Find project collaborators (29%)

Comments

Once again networking & community is the top choice. People attend NetSquared events for the people.

NetSquared is very successful at being a place to find a community of practice and develop digital skills. However, we don't offer any explicit support for people to find project collaborators or volunteering their skills. This is all happening organically through the networking, but with supporting programs we could help more attendees contribute. 🙏🏾

Have You Shared Information You've Learned at a Meetup?

Have you shared information you've learend at a meetup?

Comments

NetSquared attendees are promiscuous! 76% have shared knowledge they’ve gained at an event. And 18% report that it drove them to try a new product or change the way they work.

Has the Meetup Been Useful in Increasing Your Adoption of Technology?

 NetSquared has increased the adoption of new technology for 59% of attendees

59% of respondents report that attending NetSquared events is useful in helping them increase their adoption of new technology.

How Does NetSquared Help Your Nonprofit?

NetSquared helps nonprofits make better IT decisions

The top three responses answers to this impact question were:

  • Makes connections that help me do my job better (63%)
  • Make better IT or digital marketing decisions (60%)
  • Reach more people (60%)

Comments

Measuring the impact of a distributed network like NetSquared can be difficult, but these questions start to help us determine the difference we make for our nonprofit members. The top answers reflects the value attendees find in networking, and the ability to make better tech decisions and reach more people speaks to the skill development we offer attendees.

 

NetSquared Impact Testimonials

Finally, the last section of the survey analysis features quotes from some of the text replies to the questions "How has attending NetSquared meetups helped your organization?" We have edited some entries for brevity or clarity.

 

Testimonial from Tech for Good Brighton Meetup

NetSquared testimonial —new software and experts NetSquared very valuable to me

NetSquared testimonial — NetSquared helped me prepare a presentation for the board to persuade them to take digital transformation seriously

 

“NetSquared has introduced me to new technology, newer ways to connect with people and to find collaborators. Thanks ”

“I learned about upgrading a website and when I got back home asked my website guy to implement some of them with success.”

“I always learn something at these MeetUps! The organizers are very welcoming and encouraging. Wonderful group of people.”

“Working at a non-profit, you are strapped for time and resources so it is incredibly helpful to get help when it comes to technology. ”

“In one nonprofit, NetSquared experience helped me develop a Collection Management System with offsite backup. In another nonprofit, NetSquared enabled me to know to create a Communications Officer which is now one of the primary officers.” — Leo Kellogg, Torch Foundation

“As a consultant serving the nonprofit sector, I love seeing what technologies people are most interested in, and learning more about their needs. It really helps me do a better job serving clients, whenever I understand their perspectives and priorities better.”

“I not only learn about programs and techniques that I put to valuable use but I also meet experts who I can consult with. The meetings are very valuable to me.” — Frank Brill, EnviroPolitics

“We found the help and cost savings have been really helpful, and we will no doubt take up the discounts on any commercial software that we need to us in the future. ”

“I have enjoyed attending sessions with NetSquared and learned a lot of new things. It has allowed me to network and bounce my ideas with like minded groups.”

 

Changes to the Next Survey

No survey is perfect, especially this one! Here's some tweaks we will consider for the next survey:

  • Add question "Have you ever attended a NetSquared event?" (allows us to filter results to see active vs inactive members)

  • Revise question "What TechSoup Resources Do You Use?"

    • Change "information pages about specific products" to "product pages"
    • Add option "TechSoup discount and donation programs"

          

5372 Gold Creek Cir, DISCOVERY BAY CA $499,000, 5 beds, 3 baths

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property photo 5 beds, 3 baths, 2,583 sqft, .15 acres, Residential
Courtesy of Wilko Schutzendorf, Berkshire Hathaway-Franciscan
          

A Discovery at 59 Allen Street

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Much of the plastic enshrouding 59 Allen Street has now been taken down, revealing a detail that went unnoticed before the paint was removed: a brick semicircular arch over what must have been a window--a much larger window than the one that is there now.

The presence of this detail in the brick work raises some questions about the window that was originally there. The engraving of the house that appears on an 1858 map of Columbia County shows a tripartite window in this position with rectangular hood mouldings.

By 1954, when Howard Gibson took this picture of a fire in a nearby house on Allen Street, the smaller window that is there now is in place, with a rectangular hood moulding, similar to what appears in the 19th-century engraving, which is now missing.

So, why is there this brick semicircular arch? It would not have been needed for the window that appears in the 1858 engraving. The house was built in 1851, so it seems reasonable to assume that the engraving shows the house as it was originally.
COPYRIGHT 2019 CAROLE OSTERINK
          

Ophthalmic Technician ~ Vanderbilt Eye Institute (Lebanon) | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient
          

Ophthalmic Technician 2 ~ Vanderbilt Eye Institute (Hendersonville) | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patien
          

Ophthalmic Technician 2 ~ Vanderbilt Eye Institute (Lebanon) | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient
          

“Investigation Was A Scam”: Judicial Watch Obtains Emails Showing FBI Worked With Clinton Lawyer

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In yet another massive discovery that shows the Clinton email investigation “was a scam,” Judicial Watch just obtained more emails between Lisa Page and Peter Strzok showing that the Federal Bureau of Investigation delivered special access and accommodations to Clinton’s lawyer and ‘witnesses.’ Any other American would NOT have had this level of help during... View Article
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The post “Investigation Was A Scam”: Judicial Watch Obtains Emails Showing FBI Worked With Clinton Lawyer appeared first on Conservative Daily Post.


          

Astronaut - the new backdrop in our collection!

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Astronaut - the new backdrop in our collection!
We present to you the new backdrop in our collection!
Available now in our SHOP
 
 
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"Astronaut" is an artwork by Artrama, made as a part of the story of the compilation
"The Astronauts in the Solar System" by DJ Masala.

Listen to the compilation here ⊳

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The human race was always eager for a search of the unknown, outside of our planet, and also inside of ourselves. This search is a magnificent and unpredictable journey, because the cosmos is inconceivably big, and we can find unexpected things hiding in its corners. Every astronaut has to be brave and ready to conquer all the obstacles that lay on its way. Each of us can be this brave astronaut, as we step on this way of inner cosmos discovery. We are the outer and inner cosmos, and each step is the part of the great journey into unknown depths of reality.
 
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Land Rover Discovery, il rimorchio non si sente più

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Ancora una prova di come sia semplice guidare un rimorchio in retromarcia grazie al sistema Advanced Tow Assist


          

Best practices to optimize insurance coverage discovery and denial prevention efforts

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Erie's Gabler asks feds for more info in fraud case

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Defense compares sifting through discovery to searching for a needle in 'a giant haystack.'
          

Graduate Practical Nurse (GPN) ~ GI Clinic | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patient
          

Banyana Banyana’s Mthandi returns to Discovery Walter Sisulu Soccer Challenge

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Dec 2, 2019 | General News, News, Youth Development 2 December 2019 – Arriving at Nike Football Centre in Soweto for the start of the 2019 Discovery Walter Sisulu Soccer Challenge on Sunday, 1 December 2019, Banyana Banyana striker Amanda Mthandi was smiling from ear to ear. Not only was Mthandi looking forward to some exciting action on the day […]
          

Legal: Insurance Defense Paralegal - Fort Lauderdale, Florida

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A civil defense law firm with offices located in downtown Miami and Fort Lauderdale is seeking an experienced and professional full-time paralegal with a minimum of 3 years working in a defense law firm specializing in personal injury litigation. Candidate must be highly organized with strong research and writing skills and fully computer literate. Candidate must be able to work independently and comply with all law firm policies and procedures. Responsibilities: Managing files for litigation matters Intake and organization of voluminous production documents received from clients and opposing parties Preparing pleadings, discovery demands, discovery responses and other litigation documents at the request of the attorney Preparation of materials for depositions, hearings, mediations, and trials to assist attorneys Ability to prioritize work load based on deadlines Communicate with attorneys to assist in all aspect of litigation Ability to meet billing requirements Requirements: Experience handling both liability and damages issues Background in medical discovery and catastrophic injury cases Excellent communication skills Ability to interact with attorneys, paralegals, and other office staff in a professional manner Ability to interact with Court personnel, opposing counsel, and clients in a professional manner Must be detail-oriented with strong organizational skills Must be able to work as part of a team or individually Willingness to complete assigned tasks in a timely fashion Strong knowledge of Microsoft word, Excel, and Outlook Knowledge of ProLaw a plus Qualifications: Advanced knowledge and successful experience in managing a full case load from inception to post-trial A self-starter with excellent verbal and written skills A college degree and/or Paralegal Certification is required ()
          

Legal: Litigation Paralegal - Fort Lauderdale, Florida

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Skills - Paralegal Certificate Job Summary: Seeking experienced Commercial Litigation Paralegal in Fort Lauderdale for a well established multi-practice, commercial law firm. Requirements or Qualifications: A minimum of six years' experience working as a litigation paralegal in a large law firm (from case development to initial pleadings through discovery, trial and post-trial practice). Possess extensive trial, mediation and arbitration experience, and thorough knowledge of state and federal court systems and procedures and laws relating to evidence and trial practice. Certified paralegal with thorough knowledge of Summation, Concordance or Relativity technologies. Application Process: Contact: ******************* Selection Criteria:Application Due Date: November 15 2019 itional Information: ()
          

My Discovery While On Vacation…

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I know, I know, you’re sick of hearing about my vacation. Don’t worry, I’m not sharing vacation pics again. Rather, I want to talk about what I “discovered” in my weeks away from the screens. I believe that most serious investors are smart enough to buy cheap stocks—it’s the harder “other stuff” that separates those who excel in this industry from everyone else. I ... Read More

The post My Discovery While On Vacation… appeared first on AdventuresInCapitalism | Small Companies--Big Upside.


          

Hospitality & Tourism: Dishwasher - Boynton Beach, Florida

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About Discovery Senior Living Discovery Senior Living is a family of companies which includes: Discovery Management Group, Discovery Development Group, Discovery Design Concepts, Discovery Realty Group, Discovery Marketing Group, and Discovery At Home, a Medicare-certified home healthcare company. With almost three decades of experience, the award-winning management group has been developing, building, marketing, and operating upscale, luxury senior-living communities across the United States. With a flourishing portfolio of more than 9,500 existing home or homes under development, Discovery Senior Living has become a recognized industry leader in creating world-class, resort-style communities.Discovery Senior Living is looking for a Dishwasher to join our community ***. Responsibilities: Operates dish-washing machine to properly wash and sanitize all dishes, silverware, glasses, utensils, and cooking equipment. Maintains clean, sanitary, clutter free and safe environment in food services areas by sweeping, mopping and pressure washing floors, cleaning and sanitizing dish machine. Cleans production equipment as needed or directed by supervisor. Maintains or exceed standards of appearance, cleanliness, hygiene, and health standards. Follows daily and weekly cleaning schedules. Practices all safety and loss prevention procedures. Records and maintains documentation for the following measures for service standards and regulatory compliance. Assists in receiving of food and non-food supplies. Qualifications: High school diploma or equivalent preferred. One (1) year previous experience preferred. Ability to work flexible hours as needed. Ability to handle multiple priorities. Benefits:In addition to a rewarding career and competitive salary, Discovery offers a comprehensive benefit package. Eligible team members are offered a comprehensive benefit package including medical, dental, vision, life and disability insurances, paid time off and paid holidays. Team members are eligible to participate in our outstanding 401(k) plan with company match our Employee Assistance Program and accident insurance policies. Thank you for your interest in Discovery Senior Living careers. If you have any questions about the position you are applying for, please contact the community directly. EOE ()
          

Bone breakthrough may lead to more durable airplane wings

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Cornell researchers have made a new discovery about how seemingly minor aspects of the internal structure of bone can be strengthened to withstand repeated wear and tear, a finding that could help treat patients suffering from osteoporosis. It could also lead to the creation of more durable, lightweight materials for the aerospace industry.
          

Administration, Clerical: Administrative Assistant - Sheraton Dallas Hotel (17002EZS) - Dallas, Texas

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Heres To Your Journey with Sheraton Sheraton is one of Marriott Internationals 30 renowned hotel brands. As the worlds leading Hospitality Company, we offer unmatched opportunities for associates to grow and succeed. We believe a great career is a journey of discovery and exploration. The Sheraton Dallas Hotel located at 400 N Olive St, Dallas, TX 75201 is currently hiring a Administrative Assistant. Responsibilities include: Enter and retrieve information contained in computer databases using a keyboard, mouse, or trackball to update records, files, reservations, and answer inquiries from guests. Transmit information or documents using a computer, mail, or facsimile machine. Operate standard office equipment other than computers. Prepare letters, memos, and other documents using word processing, spreadsheet, database, or presentation software. Handle incoming and outgoing mail, including date stamping and distributing incoming mail. Create and maintain computer- and paper-based filing and organization systems for records, reports, documents, etc. Compile, copy, sort, and file records of office activities, business transactions, and other activities. Enter and locate work-related information using computers and/or point of sale systems. Follow all company policies and procedures, ensure uniform and personal appearance are clean and professional, maintain confidentiality of proprietary information, and protect company assets. Welcome and acknowledge all guests according to company standards, anticipate and address guests' service needs, assist individuals with disabilities, and thank guests with genuine appreciation. Speak with others using clear and professional language, prepare and review written documents accurately and completely, and answer telephones using appropriate etiquette. Develop and maintain positive working relationships with others, support team to reach common goals, and listen and respond appropriately to the concerns of other employees. Move, lift, carry, push, pull, and place objects weighing less than or equal to 10 pounds without assistance. Perform other reasonable job duties as requested by Supervisors. To apply now, go to: https://marriott.taleo.net/careersection/2/jobdetail.ftl?job=17002EZS Marriott International is consistently recognized as an employer of choice globally by FORTUNE magazine, DiversityInc and Great Places to Work Institute, among others. Visit www.marriott.com/careers to learn more about our workplace culture and career opportunities. Chat, engage and follow us on social media. https://www.facebook.com/marriottjobsandcareers http://www.twitter.com/marriottcareers http://www.linkedin.com/company/marriott-international http://www.instagram.com/marriottcareers @lifeatmarriott on Snapchat So, we ask, where will your journey take you? Marriott International is an equal opportunity employer committed to hiring a diverse workforce and sustaining an inclusive culture. Marriott International does not discriminate on the basis of disability, veteran status or any other basis protected under federal, TX or local laws. ()
          

IT / Software / Systems: Retail Store Manager - Garland, Texas

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KCI Wireless Job Invitation for Retail Store Manager Hi, there! We are KCI Wireless, and were stoked to welcome you to the exciting, ever-changing world of Wireless sales and service! KCI Wireless is a T-Mobile Premier Retailer for the T-Mobile and Metro by T-Mobile brands who serve over 73 million Americans. Our proud story of success over the past 26 years, led and influenced by our DOPE Team carries a legacy of Success, Growth, and True Uniqueness. The Big Picture, a Rockstar High Impact & Performing, Retail Store Manager As a Retail Store Manager, WE know retail sales inside and out, and were ready to make that next move to a leadership role like no other. WE are Sales Manager Performance Rockstars who never accept anything but 100%. WE take Personal Accountability, hold our Front-line to Standards & Goals, and know that learning and executing is simply a part of the Retail Team of Leaderships DNA. In this role, WE manage talent, inspire our team, and make sure every customer comes away with a great experience. WE Maximize our Performance Results and Income Potential. These are the qualities that it takes to be successful with us. Do you have what it takes? Are you a Rockstar? Then join Us and be a part of a Great team! As a Retail Store Manager, you will have the opportunity to: Recruit, coach, and develop the talent on your team. Create a self-discovery environment to help others become future leaders. Be known for Rockstars.Analyze your business and identify key areas of stores success and opportunities. Make decisions on strategies to drive improved business results and communicate them to your team. Become a true business owner.Be that leader that is actively involved in creating the culture for your store. Engaging with your team and assisting them to deliver a great customer experience while teaching them on how to be successful in wireless sales.Utilize your planning and organizational skills to set your store up for success. Create an environment that represents the T-Mobile brand. Teach your teams how to create a safe, secure, and profitable environment.Utilize your skills in analyses and problem-solving. Leverage the ability to partner with others to achieve better results for your team and the company.Create and execute communication strategies for individuals, the store team, and others through meetings, emails, and group discussions. The experience you'll bring. This is the big leagues. Youve got a lot of responsibility and people looking to you for guidance and leadership. Ready to bring it? Good. Heres a little more on what were looking for: Youve got prior sales and sales management experience with a customer-focused retailer This includes previous consultative sales in consumer technology, coupled with a demonstrated record of high achievementYouve also got experience in operational, financial and performance management, having previously managed site profit and loss Youve got a unique ability to lead and coach people to deliver great resultsPeople who know you would say youre an amazing communicator, both with customers and teammatesYouve got solid computer proficiencyA high school degree or GED is essential, while a bachelors degree is preferred PandoLogic. Keywords: Store Manager, Location: Garland, TX - 75046 ()
          

Education / Teaching: Assistant Professor Tenure System - East Lansing, Michigan

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h3Working/Functional Title/h3 Assistant Professor Tenure System h3Position Summary/h3 Michigan State University#8217;s Eli Broad College of Business, Department of Supply Chain Management, has an opening for a tenure system assistant professor in sourcing/supply management or related areas at the intersection of sourcing and operations for the 2020-2021 academic year. Duties include research, teaching, and service. Salary and terms are negotiable depending on experience and rank. h3Required Degree/h3 Doctorate h3Minimum Requirements/h3 The position requires a Ph.D. or equivalent degree from an accredited university. The successful candidate will be expected to teach sourcing/supply management courses at the undergraduate and graduate levels. h3Desired Qualifications/h3 We seek an individual conducting high quality research in contemporary sourcing/supply management topics or related areas at the intersection of sourcing and operations that appeal to leading journals as well as industry. Examples of topical areas include, but are not limited to, supply chain risk, supply networks, leveraging supplier capabilities, buyer-supplier relationships, green procurement, and electronic sourcing (including blockchain, artificial intelligence, and cognitive procurement). #160;Candidates with expertise and interest in business analytics will be given priority.#160; An ideal candidate will have prior experience in teaching sourcing/supply management courses. h3Required Application Materials/h3 CV, cover letter h3Special Instructions/h3 Review of applications will begin October 31, 2019 and continue until the position is filled. To ensure full consideration, applications should be received by November 25, 2019. For additional information, please contact Dr. Tobias Schoenherr (****************). h3Review of Applications Begins On/h3 10/31/2019 h3Website/h3 ******************************** h3MSU Statement/h3 Michigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges. ()
          

Other: Specialist - Curric Dev-On-Call - East Lansing, Michigan

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Specialist - Curric Dev-On-Call Job no: 612001 Work type: Faculty/Academic Staff Major Administrative Unit / College: College Of Osteopathic Medicine Department: Institute For Global Health 10034463 Salary: Pay Commensurate with Experience Location: East Lansing Categories: Faculty Academic Staff On-Call, Non-Union, On-Call, Health Care Professional Position Summary The Institute for Global Health within the College of Osteopathic Medicine at Michigan State University is seeking outstanding candidates for anticipated fixed-term (non-tenure system) faculty positions in the Master of Science in Global Health program. Primary responsibilities will be course development of online graduate courses and contributing to the program assessment and quality. Applicants in this pool are reviewed as needed when the program has an immediate need to fill a vacancy, beginning as soon as possible. Required Degree Masters Minimum Requirements Master's degree (global health or related discipline) International field experience High level of interpersonal, verbal, visual and written communication skills Experience with a wide range of computer software, hardware, and computing tools Must be familiar with the following technologies: D2L and other learning management systems Google Apps and other cloud-based software Online communication tools (Zoom, Google, etc.) Desired Qualifications A PhD in global health or related field and recent global health experience; Hires will be ranked based on education, experience, commitment to working as part of a team, commitment to student experience, and excellence in communication and leadership skills. Required Application Materials CV/resume and cover letter Responses to the following questions: 1. Please describe your interest and experience in global health field work (200 word limit) 2. Please describe your experience in course development and instruction (200 word limit) Work Hours Hours will vary due to availability of applicant and need of department. Review of Applications Begins On 10/11/2019 MSU Statement Michigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges. Advertised: Sep 27, 2019 Eastern Daylight Time Applications close: Sep 26, 2021 Eastern Daylight Time ()
          

Other: Specialist - Advisor-Fixed Term - East Lansing, Michigan

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Specialist - Advisor-Fixed Term Job no: 622020 Work type: Faculty/Academic Staff Major Administrative Unit / College: International Studies And Programs Department: International Studies And Programs Dean 10054474 Salary: Salary Commensurate with Experience Location: East Lansing Categories: Part Time (1-49.9%), Fixed Term Academic Staff, Advising/Counseling Working/Functional Title Fulbright Advisor Position Summary Michigan State University seeks an individual for a one-year (twelve month) appointment as a Specialist-Advisor, with as working title of Fulbright Advisor, at 25% effort that will work to provide accurate information and guidance to current and prospective students on various Fulbright student scholarship program types and assist with finding the best program for an individual's particular interests, skills and experiences. Essential Duties & Responsibilities Advising (25%) Serving as MSU's principal advisor and representative to current and prospective outgoing student Fulbrighters. This includes answering inquiries; working with individual applicants on their project proposals and procedural matters; and submitting applications and supporting materials for those requiring institutional submissions Serving as MSU's official liaison with the Department of State, Department of Education, Institute for International Education, national Fulbright commissions and U.S. embassies. and other government and nongovernmental entities involved with the programs Promoting Fulbright programs, including actively promoting and recruiting students to apply. This includes organizing workshops and other informational sessions and outreach for prospective applicants Serving as the ISP Dean's Office Fulbright liaison with other units on campus, such as colleges and departments/schools, academic advisors, Graduate School, Honors College and Associate Provost for Undergraduate Education Working with other ISP units and affiliates, such as area studies and thematic centers and institutes, and the Office for International Students & Scholars, to advance the university's Fulbright engagement and to provide venues for student Fulbrights to make public presentations about their experiences Ensuring that the content on MSU's Fulbright website remains current and updated Required Degree Masters Desired Degree Doctorate Minimum Requirements A master's degree; One to three years of experience with student scholarship or cohort group management; One to three years of experience with student advising or mentoring; Highly organized and motivated individual; Excellent written and oral communication skills. Desired Qualifications International experience as well as experience working with high achieving students, an honors program or similar programmatic area. Required Application Materials CV and letter of interest Website Department Statement The Fulbright Program is the flagship international educational exchange program sponsored by the U.S. government, designed to increase mutual understanding between the people of the U.S. and the people of other countries. Fulbright is active in more than 160 countries. The program provides grants to cover round trip air travel, a monthly living stipend (to cover food, lodging, local transportation, and miscellaneous expenses), supplemental health and accident insurance, and, in some cases, tuition waivers, and research allowances. MSU Statement Michigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges. Advertised: Nov 18, 2019 Eastern Standard Time Applications close: Dec 2, 2019 Eastern Standard Time ()
          

Other: Specialist - Outreach-Fixed Term - East Lansing, Michigan

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Specialist - Outreach-Fixed Term Job no: 564734 Work type: Faculty/Academic Staff Major Administrative Unit / College: College Of Osteopathic Medicine Department: Neurology And Ophthalmology Com 10034625 Salary: Salary Commensurate with Experience Location: East Lansing Categories: Full Time (90-100%), Fixed Term Academic Staff, Health Care Professional, Health Care Support, Non-Union Position Summary Physician Assistant will work with a high level of autonomy in collaboration with vascular neurologists and neuro-interventionalists and other health care professionals to provide health care across the continuum of care for patients with Neurological disorders, in particular, cerebrovascular disease/stroke in an outpatient setting. The physician assistant will provide specialty care with aspects of medical care focusing on the patient as a whole person. The provision of care includes but is not limited to: comprehensive assessment, ordering, conducting and interpreting diagnostic tests, prescription of pharmacological agents and treatments, and non-pharmacological therapies. Will provide teaching to patients and family related to disease management awareness and prevention. Assumes lead roles in educational projects, course development and presentations in specified focus areas. Participates in research projects in conjunction with departmental faculty. This is a full time position in a multi-specialty neurology clinic within a university department. Required Degree Masters -Master of Science in Physician Assistant Minimum Requirements Graduate of an accredited PA educational program. Current NCCPA certification and eligibility for licensure in the State of Michigan. Desired Qualifications Two to five years of clinical experience is preferred but not required. Neurology experience is preferred but not required. Excellent verbal, written and oral communication skills. Demonstrated leadership ability. Flexibility to adjust schedule to meet patient and staff needs. Ability to manage time and stress effectively and adapt to unpredictable situations within the patient care setting. The successful candidate will receive sufficient and focused training and orientation to become a successful and integral part of the HealthTeam. Required Application Materials Letter of Interest CV Special Instructions Review of applications will continue until the position is filled. Review of Applications Begins On 04/26/2019 Summary of Health Risks Exposure to human blood, serum, tissue and other body fluids; and materials covered under Universal Precautions; TB risk or work within 3 feet of human patients in a health care setting or have potential exposure to animals or to specimens with Mycobacterium. Website MSU Statement Michigan State University has been advancing the common good with uncommon will for more than 160 years. One of the top research universities in the world, MSU pushes the boundaries of discovery and forges enduring partnerships to solve the most pressing global challenges while providing life-changing opportunities to a diverse and inclusive academic community through more than 200 programs of study in 17 degree-granting colleges. Advertised: Apr 16, 2019 Eastern Daylight Time Applications close: Apr 16, 2021 Eastern Daylight Time ()
          

Fine-tuning gene expression during stress recovery

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Credit: Hokkaido University Scientists have discovered non-coding RNA has a novel role to fine-tune gene expressions during stress recovery, getting closer to uncovering a 30-year-old nuclear mystery. Hokkaido University researchers are beginning to uncover the functions of mysterious organelles in the nucleus and their relation to stress, 30 years after their discovery. The organelles, called […]
          

Viu, Discovery team on factual, lifestyle programming

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Viu, Discovery team on factual, lifestyle programming Details Joseph O'Halloran | 29 November 2019 PCCW Media Group’s OTT service Viu has embarked on a collaboration with content giant Discovery to bring factual and lifestyle entertainment content to digital audiences in Southeast Asia. The deal will see Viu subscribers gain access to Discovery Networks Asia Pacific channels on an on-demand basis, including Discovery, Discovery Asia, Animal Planet, Food Network, TLC and HGTV. Such channels offer genres such as lifestyle content, reality content and docuseries. The content will be available in six markets, including Hong Kong, Indonesia, Malaysia, the Philippines, Singapore, and Thailand. Viu subs will also have access to Asian Food Network content. Content will be in English, Bahasa Melayu, Bahasa Indonesia, Traditional Chinese, and Thai subtitles per as-available basis. Commenting on the deal, Viu chief executive officer Janice Lee said: “Having firmly established a highly engaged user base in the past few years, our collaboration with Discovery marks a further step in the continual expansion of our offerings to enrich the content experience for our viewers through international and regional collaborations as well as through the development of Viu Original. With Discovery we see the opportunity to offer top quality factual and lifestyle entertainment, including travel, lifestyle and living, that resonates with a broad spectrum of our audience on the Viu platform.” Discovery Networks Asia Pacific vice president and general manager Anna Pak Southeast added: “We are excited to partner with Viu and expand the reach of our brands to digital audiences. With its large and growing fanbase, Viu is an obvious partner as a leading OTT platform in APAC and our partnership will bring new business opportunities to Discovery. “Our earlier collaboration with Viu on No Sleep No FOMO provided us with a deeper understanding of Viu’s expanding user base across the region and the high-quality service it provides. This is particularly important to us as a premium brand and our efforts to offer our modernised Asian Food Network content to a broader
          

Egypt: Archeologists find 3,500-year-old wooden coffins

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  Three people, at least two of them women, were buried in the city of Luxor some 3,500 years ago. A team of French archeologists has discovered their coffins in the necropolis of al-Asasif, complete with original paint. Egyptian authorities on Wednesday confirmed the latest archeological discovery to come from the ancient city of Luxor— three […]

The post Egypt: Archeologists find 3,500-year-old wooden coffins appeared first on Cairo Herald.


          

Could hibernation treat obesity? Obese people share similar genes with hibernating animals

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The discovery, reported today in a new study by the University of Utah, could shed light on the root causes of metabolic disorders and ways to treat, or even cure, them.
          

Custom and Lab filtration Specialist Nordics/BeNeLux

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Custom and Lab filtration Specialist Nordics/BeNeLux - Altele

General Electric Healthcare GE Healthcare provides transformational medical technologies and services to meet the demand for increased access, enhanced quality and more affordable healthcare around the world.  GE works on things that matter - great people and technologies taking on tough challenges. From medical imaging, software & IT, patient monitoring and diagnostics to drug discovery, biopharmaceutical manufacturing technologies and performance improvement solutions, GE Healthcare helps medical professionals deliver great healthcare to their patients.   GE is committed to taking on the world’s toughest challenges. In order to fulfill that promise we rely on a culture of leadership, diversity and inclusiveness. We aim to employ the world’s brightest minds to help us create a limitless source of ideas and opportunities. We believe in hiring talented people of varied backgrounds, experiences and styles…people like you! As Custom and Lab filtration Specialist you will be responsible...

    Companie: GE Healthcare
    Tipul locului de muncă: Full-time

          

Engineering: Sr. Principal Mechanical Engineer - Huntington Beach, California

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At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems in air and space that impact people's lives around the world today, and for generations to come. Our work preserves freedom and democracy, and advances human discovery and our understanding of the universe. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have a lot of fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history. Northrop Grumman Aerospace Systems is seeking a Principle Engineer Mechanical to join the Mechanical Ground Systems Engineering team to develop Mechanical Ground Support Equipment (MGSE) in support of the Integration and Test (I&T) of Space Systems located in Redondo Beach, CA. The candidate will use a systems engineering approach to analyze requirements and design a mechanical solution by creating 3D models and drawings utilizing CATIA V5. In particular, the candidate will create layout drawings, fabrication drawings and engineering change orders, give design review presentations and perform fundamental types of analysis (e.g. strength of materials). Other tasks will include fabrication engineering liaison support, hardware testing, and supporting I&T operations as related to MGSE usage and processing. Basic Qualifications: Bachelor of Science Degree in a STEM (Science, Technology, Engineering, or Math) field with at least 9 years of engineering experience; OR Master of Science in a STEM (Science, Technology, Engineering, or Math) field with at least 7 years of engineering experience Experience creating 3D models and drawings for fabrication utilizing CAD Practical working experience with Geometric Dimensioning & Tolerance (GD&T) Candidate must have and be able to maintain an active U.S. Government security clearance at the Top Secret level with a background investigation date within 6 years, OR must have and be able to maintain an active U.S. Government SCI access with a Single Scope Background Investigation (SSBI) completed within the last 5 years. Preferred Qualifications: Degree in Mechanical or Aerospace Engineering Previous experience with CATIA V5 Previous experience with Risk and Earned Value Management Systems (EVMS) Previous experience leading and mentoring engineers Experience in Support Equipment or Tooling design; weldments, load bearing fixtures, and lifting equipment Experience in I&T operations as related to MGSE usage and processing Active SCI/SSBI Northrop Grumman is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO/AA and Pay Transparency statement, please visit www.northropgrumman.com/EEO. U.S. Citizenship is required for most positions. ()
          

Hospitality & Tourism: Concierge Attendant - Torrance Marriott Redondo Beach (17001NQM) - Downey, California

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Heres To Your Journey with Marriott Hotels Resorts Suites Marriott Hotels Resorts Suites is one of Marriott Internationals 30 renowned hotel brands. As the worlds leading hospitality company, we offer unmatched opportunities for associates to grow and succeed. We believe a great career is a journey of discovery and exploration. The Torrance Marriott Redondo Beach, located at 3635 Fashion Way, Torrance, CA, 90503 is currently hiring a Concierge Attendant. Responsibilities include: Complete final breakdown of function, by cleaning the room, and cleaning and returning equipment to its proper location. Complete closing duties, including storing all reusable goods, locking doors, breaking down goods, etc. Set up, stock, and maintain work areas. Monitor and maintain cleanliness, sanitation, and organization of assigned station and service areas. Transport dirty linen to correct area to be cleaned, separate napkins from tablecloths, and restock linen shelves with clean linens. Maintain cleanliness of work areas throughout the day, practicing clean-as-you-go procedures. Assist other departments when needed to ensure optimum service to guests. Follow all company and safety and security policies and procedures; report any maintenance problems, safety hazards, accidents, or injuries; complete safety training and certifications. Ensure uniform and personal appearance are clean and professional. Maintain confidentiality of proprietary information; protect company assets. Support all co-workers and treat them with dignity and respect. Support team to reach common goals. Comply with quality assurance expectations and standards. Move, lift, carry, push, pull, and place objects weighing less than or equal to 50 pounds without assistance. Assist with moving, lifting, carrying, and placing of objects weighing in excess of 75 pounds. Stand, sit, or walk for an extended period of time or for an entire work shift. Read and visually verify information in a variety of formats (e. g., small print). Grasp, turn, and manipulate objects of varying size and weight, requiring fine motor skills and hand-eye coordination. Reach overhead and below the knees, including bending, twisting, pulling, and stooping. Move over sloping, uneven, or slippery surfaces and steps. Move up and down stairs and/or service ramps. Welcome and acknowledge all guests according to company standards. Speak with others using clear and professional language, and answer telephones using appropriate etiquette. Perform other reasonable job duties as requested by Supervisors. Marriott International is an equal opportunity employer committed to hiring a diverse workforce and sustaining an inclusive culture. Marriott International does not discriminate on the basis of disability, veteran status or any other basis protected under federal, state or local laws. ()
          

Engineering: Sr. Principal Mechanical Design Engineer 4 - Culver City, California

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At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems in air and space that impact people's lives around the world today, and for generations to come. Our work preserves freedom and democracy, and advances human discovery and our understanding of the universe. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have a lot of fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history. Northrop Grumman Aerospace Systems located in Redondo Beach, CA has an opening for a Sr. Principal Mechanical Design Engineer 4. The selected candidate will support Spacecraft programs and Advanced Technologies and will participate in the resolution of complex mechanical design problems for space based platforms and missions involving composite and metallic spacecraft structures. The candidate will perform mechanical design of spacecraft structures, deployables, and opto-mechanical design. Duties include requirements definition, conceptual design, preliminary / layout, and detail design, drawing release, design review presentations, and support to fabrication. Responsibilities will include leading a work package including interfacing with customer, technical support, proposal technical inputs, cost estimating, directing and mentoring junior engineers, and meeting schedule and cost commitments. The candidate will work closely with stress, manufacturing, materials and processes and test to develop design requirements, define structural load paths, develop CAD models and prepare engineering drawings to fabricate flight and structural test articles. He/she will provide close integration and oversight of Suppliers to verify/validate mechanical design requirements and ensure qualification/certification deliverables are provided and meet requirements. The position requires extensive experience in: both Composite and Metallic Mechanical Design; knowledge of other related disciplines; exposure to scheduling, budgeting, & risk management; and full understanding of requirements for SRR, IDR, PDR & CDR. Basic Qualifications: Bachelors of Science Degree in Engineering (Mechanical Engineering, Civil Engineering, Aerospace Engineering) with 9 years of experience designing composite and/or metallic primary and secondary Aerospace structures OR Master's Degree in Engineering (Mechanical Engineering, Civil Engineering, Aerospace Engineering) with 7 years of experience designing composite and/or metallic primary and secondary Aerospace structures OR a PhD in Engineering (Mechanical Engineering, Civil Engineering, Aerospace Engineering) with 4 years of experience designing composite and/or metallic primary and secondary Aerospace structures. Working knowledge of CAD Experience with engineering drawings and related Bill-of-Materials. Experience with Geometric Dimensioning &Tolerance applications (GD&T). Experience withtolerance stack-up analysis. Experience working in anAerospace design team environment. Ability to obtain and maintainSCI or DoD Secret clearance Excellent verbal and written communication skills, be skilled in use of the Microsoft Office software suite (Outlook, Word, Excel, PowerPoint). Preferred Qualifications: Working knowledge of CATIA V5 or NX 10 Experience working on Special Access Programs is preferred. Participation in multiple design cycles in spacecraft development programs is desirable. Current (in scope) DoD Secret and SCI clearances is preferred. Previous leadership of a spacecraft structural engineering team is preferred. Northrop Grumman is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO/AA and Pay Transparency statement, please visit www.northropgrumman.com/EEO. U.S. Citizenship is required for most positions. NGLinkedAS 1NGSPACE ()
          

Engineering: Sr. Principal Mechanical Design Engineer 4 - Lynwood, California

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At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems in air and space that impact people's lives around the world today, and for generations to come. Our work preserves freedom and democracy, and advances human discovery and our understanding of the universe. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have a lot of fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history. Northrop Grumman Aerospace Systems located in Redondo Beach, CA has an opening for a Sr. Principal Mechanical Design Engineer 4. The selected candidate will support Spacecraft programs and Advanced Technologies and will participate in the resolution of complex mechanical design problems for space based platforms and missions involving composite and metallic spacecraft structures. The candidate will perform mechanical design of spacecraft structures, deployables, and opto-mechanical design. Duties include requirements definition, conceptual design, preliminary / layout, and detail design, drawing release, design review presentations, and support to fabrication. Responsibilities will include leading a work package including interfacing with customer, technical support, proposal technical inputs, cost estimating, directing and mentoring junior engineers, and meeting schedule and cost commitments. The candidate will work closely with stress, manufacturing, materials and processes and test to develop design requirements, define structural load paths, develop CAD models and prepare engineering drawings to fabricate flight and structural test articles. He/she will provide close integration and oversight of Suppliers to verify/validate mechanical design requirements and ensure qualification/certification deliverables are provided and meet requirements. The position requires extensive experience in: both Composite and Metallic Mechanical Design; knowledge of other related disciplines; exposure to scheduling, budgeting, & risk management; and full understanding of requirements for SRR, IDR, PDR & CDR. Basic Qualifications: Bachelors of Science Degree in Engineering (Mechanical Engineering, Civil Engineering, Aerospace Engineering) with 9 years of experience designing composite and/or metallic primary and secondary Aerospace structures OR Master's Degree in Engineering (Mechanical Engineering, Civil Engineering, Aerospace Engineering) with 7 years of experience designing composite and/or metallic primary and secondary Aerospace structures OR a PhD in Engineering (Mechanical Engineering, Civil Engineering, Aerospace Engineering) with 4 years of experience designing composite and/or metallic primary and secondary Aerospace structures. Working knowledge of CAD Experience with engineering drawings and related Bill-of-Materials. Experience with Geometric Dimensioning &Tolerance applications (GD&T). Experience withtolerance stack-up analysis. Experience working in anAerospace design team environment. Ability to obtain and maintainSCI or DoD Secret clearance Excellent verbal and written communication skills, be skilled in use of the Microsoft Office software suite (Outlook, Word, Excel, PowerPoint). Preferred Qualifications: Working knowledge of CATIA V5 or NX 10 Experience working on Special Access Programs is preferred. Participation in multiple design cycles in spacecraft development programs is desirable. Current (in scope) DoD Secret and SCI clearances is preferred. Previous leadership of a spacecraft structural engineering team is preferred. Northrop Grumman is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO/AA and Pay Transparency statement, please visit www.northropgrumman.com/EEO. U.S. Citizenship is required for most positions. NGLinkedAS 1NGSPACE ()
          

Discovery

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Discovery
          

Other: Sr. Principal Communications System Engineer (Restricted Clearance Required) - Monterey Park, California

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At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems in air and space that impact people's lives around the world today, and for generations to come. Our work preserves freedom and democracy, and advances human discovery and our understanding of the universe. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have a lot of fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history.Northrop Grumman Aerospace Systems is seeking a Communications Systems Engineer4 to work in Redondo Beach, California. The Communications Systems Engineer4 will support architecture trades, design analysis, and performance modeling through computer simulation. This individual will provide systems engineering support to hardware developments for air, space, and ground systems utilizing state-of-the-art antenna, RF, digital, and microelectronics technologies. Project roles span all phases of product development cycle, from new business acquisition, and IRAD/ technology development to established programs delivering integrated hardware and software systems. Systems engineering activities include system architecture design, trade studies, specification development, requirement definition and allocation, performance analysis and simulation; system modeling and simulation tool development, and support to hardware design, manufacturing, integration and test.Essential experience in the following areas: Communication systems RF and digital hardware design Baseband and digital signal processing Waveform design Signal detection and estimation Synchronization theory Networking SOUTHBAYJOB . Basic Qualifications: Bachelors of Science degree in a STEM (Science, Technology, Engineering, or Math) field from an ABET accredited institution and9 years of engineering experience in an aerospace environment OR Masters of Science degree in a STEM (Science, Technology, Engineering, or Math) field from an ABET accredited institution and7 years of engineering experience in an aerospace environment OR Doctorate of Science degree in a STEM (Science, Technology, Engineering, or Math) field from an ABET accredited institution and4 years of engineering experience in an aerospace environment Practical working experience with system architecture design, trade studies, and performance analysis and simulation Technical experience with supporting hardware development utilizing antenna, RF, digital, and microelectronic technologies Currently possess an Active In-Scope SSBI clearance Preferred Qualifications: AdvancedDegree in Electrical Engineering, Physics, or Computer Science Completed relevant coursework in Communication Theory and Digital Signal Processing Experience with baseband and digital signal processing, and waveform design Possess strong leadership qualities, as well as strong verbal and written communication skills Northrop Grumman is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO/AA and Pay Transparency statement, please visit www.northropgrumman.com/EEO. U.S. Citizenship is required for most positions. ()
          

IT / Software / Systems: Software Engineer (Clearance Required) - Buena Park, California

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At Northrop Grumman, our employees have incredible opportunities to work on revolutionary systems in air, space and on the ground that impact people's lives around the world today, and for generations to come. Our work preserves freedom and democracy, and advances human discovery and our understanding of the universe. We look for people who have bold new ideas, courage and a pioneering spirit to join forces to invent the future, and have a lot of fun along the way. Our culture thrives on intellectual curiosity, cognitive diversity and bringing your whole self to work - and we have an insatiable drive to do what others think is impossible. Our employees are not only part of history, they're making history. Northrop Grumman Aerospace Systems is seeking experienced Software Engineers to join our diverse team, developing, enhancing and maintainingcapabilities for Overhead Persistent Infrared (OPIR) satellite payload andground systemsfor payload data processing. This position islocated inAzusa, CA at the foot of the San Gabriel Mountains in Los Angeles County. Our software engineering teams offer flexible work arrangements as well as career,technical and personaldevelopment opportunities. In this role, the selected candidate will be expected to: Communicate and work effectively with team members and leads in an agile and dynamic team environment Take ownership of tasks assigned by team lead Design, develop, document, test, integrate and debug software written in various computer languages Meet project milestones while ensuring software standards are met Develop technical solutions to complex problems Interface with other groups and subject matter experts within and outside of the project Basic Qualifications: Bachelor's Degree in a Science, Technology, Engineering or Mathematics (STEM) discipline with 2 years related experience OR Master's Degree in STEM discipline with 0 years related experience Proficiency in one or more of the following: C/C++, Java, Python * Possess knowledge of the software lifecycle Active/Current DoD Secret or Top Secret Clearance or SCI program access is required. Preferred Qualifications: Demonstrated ability to implement process improvement, streamline activities, and develop efficiencies Excellent communication and organizational skills; strong interpersonal and analytic skills Previous in-depth domain knowledge of program software design and code * Experience in standard Software Engineering processes and development lifecycle including software architecture, design, development, integration, test and verification, including experience in writing software test plans and test procedures Experience in Object Oriented Design and Unix/Linux platform development Experience with software configuration management and version control tools such as ClearCase, Git/GitHub, Subversion Experience in Agile/Scrum development concepts, methodologies and tools Experience in Real Time Operating Systems (RTOS) such as VxWORKS Northrop Grumman is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO/AA and Pay Transparency statement, please visit www.northropgrumman.com/EEO. U.S. Citizenship is required for most positions. ()
          

The Long Lost Art of Being Found

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Among the most of remarkable Hollywood tales is the discovery of movie actress Lana Turner at the soda fountain in Schwab’s drug store in Hollywood,…

The post The Long Lost Art of Being Found appeared first on mythehealth.


          

Loosely Coupled Organizations Revisisted

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Over the past two decades organizational analysts have become increasingly intrigued by those complex organizations which, despite appearing to be highly rationalized, paradoxically seem to lack expected levels of internal coordination and control of their productive activities and employees. The resulting body of research has popularized several new labels for such organizations - loosely coupled systems and organized anarchies.

This essay evaluates this line of research by focussing on its analysis of schools, which are usually considered to be the epitome of loosely structured organizations. In brief, I disagree with this perspective's conclusions and argue that distinguishing the mode and degree of organizational coupling and control depend on where, by what criteria and how one looks. My contention is that although this debunking perspective ostensibly rejects tidy rational and efficiency models of organization, ironically it unwittingly employs many of the latter's assumptions of organizational behavior. In particular, these analysts adopt, I argue, a framework that precludes the discovery of both the degree and forms of organizational control within schools.

Subsequently, by re-examining and re-interpreting the existing research on school organization, this paper identifies and illustrates a range of institutional and organizational mechanisms by which schools and the work of teachers are constrained and circumscribed.


          

The Billionaire Murders: The Mysterious Deaths of Barry and Honey Sherman by Kevin Donovan

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BrianEWilliams's review: "This an examination of the suspicious deaths of Toronto billionaires, Barry & Honey Sherman, in December 2017. The author Kevin Donovan is a Toronto investigative journalist. He begins with an account of the discovery of the bodies in the Shermans' home which actually happened when a realtor was taking potential buyers through the house. The writing then moves on to the police investigation. Interspersed with his reporting about the investigation he explores the victim's lives: their family, their business, their philanthropy, He casts doubts on the professionalism of the Toronto police: they decided early on that it was a murder-suicide despite a lack of evidence of such. Thus, they did not explore other possible options until forced to do so by a private investigation undertaken on behalf of the family. The biographical information about the Shermans and their lives is fascinating. While they had lots of money, they lived frugally. Barry was prone to invest money in losing ventures; who knew that he . invested in movies and craft beer start-ups? The Shermans are sympathetically portrayed. In the end, Donovan advances some views on the identity of their killer: someone with intimate knowledge of the couple and their routine, snd that their home did not have security cameras. He dismisses the idea it was a professional killing; the set up of bodies to look like a murder-suicide was too amateurish (even though it led the Toronto police astray). This reader is left with an impression that the identity of the killer is known, but proof is so far lacking. Also, wondering about whether the Toronto police are up to the task of investigating a high-profile murder. A good read."
          

Attorney

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Attorney

Raymond is a self-employed Attorney in the New Fairfield, CT area. Having practice law for over 35 years now, Raymond represents a wide range of clients in various cases, from family law matters such as wills and divorce to criminal court hearings. Raymond walks us through the life-cycle of a case, from meeting the client through discovery and trial.

Added by: CandidCareerTeam
Tags: attorney, law, lawyer, legal, litigation, general, private, practice, court, hearing, justice, investigation, discovery, wcsu
Date: 2018-05-08




          

541: Jon Warner – The Winning Start-up Formula

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Often when launching a new company or business, we are looking for a map that will guide us from seed to conception. On my journey, I looked for any source that would help me on my path. Some strategies worked, but many of them did not.

Looking back, I have to think of how helpful it would have been if someone would have been able to provide a map or guideline that spoke to my specific needs. A plan that lays out the process, framework, and proper sequencing of events that will reap the most significant benefits. 

To dive deeper into launching a start-up, I’ve brought on serial entrepreneur, advisor, and author Jon Warner. Five-time company CEO, Jon Warner is a widely respected entrepreneurship expert and mentor having founded and led 3 start-ups. Jon is a noted speaker at businesses, colleges, and conferences across the world. He also lectures on entrepreneurship at both undergraduate and MBA levels. Jon is also a prolific author, having published 40 books, all concerning business, management, leadership, entrepreneurship, and innovation.

To find out how the vital steps to launching a successful start-up, download this episode now.

THE CURIOSITY WARRIOR

"No plan survives first contact with the customer." - Jon Warner

Highlights -

  • The necessary framework for a start-up company. 
  • The concept of a lean start-up created by Toyota. 
  • Put customer needs before your needs. 
  • Execute every plan in the proper sequence. 
  • Structure and schedule your day by keeping the end in mind. 
  • Understand the difference between customer discovery and customer research. 
  • Make sure that you always distinguish yourself from the competition. 

Guest Contact -

Contact Jeffrey -

Mentions -

Steve Blank Book: Four Steps to the Epiphany

Resources -

Have Your Website Brand Message Reviewed! Is your website and are all your marketing materials speaking the right LINGO of your ideal customers? Often it's not which is why you're not converting traffic and leads to clients and attracting your most profitable customers. Fill out the simple LINGO Review application and I'll take a look at your website. If I have suggestions for you to improve your brand message (I almost always do), we'll set up a complimentary 30-minute call to discuss. A select number of websites are also chosen for my LINGO Review Video Series. Fill out the application today and let's get your business speaking the right LINGO!

Music by Jawn


          

Call for applications: Women in Politics – confidence, influence and effective leadership

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Background:

As key global players and partners in the full implementation of the Women Peace and Security (WPS) agenda, the United Nations and European Union consistently promote gender equality, women's empowerment and women's rights in line with UN Security Council resolution 1325 and the nine other resolutions on WPS. The EU Council conclusions on Women, Peace and Security adopted on 10 December 2018, state that implementation of the WPS agenda can only be achieved by “integrating a gender perspective and women's participation in all contexts, from conflict analysis to subsequent actions, including dialogue facilitation, mediation, peace negotiations and other conflict prevention and resolution tools.” 

Almost twenty years after the adoption of UNSCR 1325, women in Kosovo remain underrepresented in decision-making bodies at central and local levels despite the presence of well-established women’s networks, highly-effective women leaders and an advanced legislative framework that obliges legislative, executive and judicial bodies to adopt and implement special measures to ensure equal representation of women and men. While the 30 per cent quotas under the electoral laws are met in Kosovo Parliament and Municipal Assemblies, the requirement of equal participation of men and women under the Law on Gender Equality has not been met. Very few women occupy decision making positions in political parties. Women's representation at government remains below the legal requirement of 50 per cent. At the local level, although there was a percentage point increase in the representation of women in Municipal Assemblies, there are no women holding mayoral positions. This was also noted in the 2019 EU progress Report along with the lack of implementation of the respective legal framework. In addition, women’s limited participation in current political negotiations in the broader region, including Kosovo, has been highlighted as a concern by the EU and in recent reports of the United Nations Secretary-General on Kosovo. 

Project Description:

The project consists of three different components with a focus on enabling women to reflect about their experiences, to examine their patterns of behaviour that might be standing in their way towards more full participation in the public life in Kosovo and to distinguish these from the structural limitations to exercising their leadership more fully.

 

First, a five-day leadership training for 15 women leaders and influencers will be held in Pristina between 9-13 December 2019. It will blend elements of personal self-discovery, practical skills and leadership strategies to master challenges in the workplace and public life (including political parties and offices). During the training a personalized learning and roadmap will be developed for each participant followed by coaching sessions. The coaching sessions will be provided to all the women individually. Second, the selected 15 women will participate at a networking event that will be organized in Brussels (in February 2019). This two-day study visit will be an opportunity for the women leaders to meet with other prominent women from the EU institutions (Commission, Parliament) and the European Women's Lobby. The networking will enable the women to establish contacts and future cooperation in the field of empowerment of women and gender equality. Third, a workshop on “Good Governance and accountability” with special focus on gender responsive and inclusive political processes will be held in Pristina in February 2019. In this workshop participants will discuss how to ensure that the principles of inclusive, accountable governance go beyond rhetoric, be that in government institutions, within the political parties, in civil society organizations, media and other spheres of public life. 

 

1.    

 

Project title:

 

 “Women in Politics – Confidence, influence and effective leadership” – Phase 2

 

“Ensuring Gender Responsive and Inclusive Political Dialogue Processes”

2.

Call for applications issued on:

 

Deadline for applications:

 15 November 2019

     

28 November 2019, 5:00 p.m.

3.

Organizer:

European Union Special Representative in Kosovo and United Nations

4.

Number of candidates to be selected:

 

15

5.

Qualifications and skills:

Politically affiliated women or women with strong political interest that come from academia, civil society or media. Extensive professional experience in one of the fields of relevance in public/political life; Strong willingness and motivation to take on senior posts or to play a key influencing role in the future;6. 6.

General Professional Experience:

University degree as a minimum, advanced qualification is an asset; Computer literate; Advanced interpersonal and communication skills;

7.

How to Apply:

 

Applicants are required to send their applications in English (CV and motivation letter) by e-mail to: Albana GJINOLLI Albana.GJINOLLI@eusrinkosovo.eu (link sends e-mail) and copying Annette M. Fath-Lihic Annette.fath-lihic@ext.eeas.europa.eu (link sends e-mail)

 


          

Johnson Bolsters Security Message After London Knife Attack

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Johnson Bolsters Security Message After London Knife Attack(Bloomberg) -- Sign up to our Brexit Bulletin, follow us @Brexit and subscribe to our podcast.Boris Johnson’s Conservatives will paint their party as one of law and order on Monday, while London reels from a terror attack and prepares to welcome Donald Trump this week for a NATO summit.Both the president’s visit and the deadly assault threaten to derail campaigning and crimp the Tories’ lead over Labour, less than two weeks before the U.K. votes in the general election.When Trump lands in London on Monday, Johnson will be hoping he doesn’t say anything that hinders his lead in the polls. Trump’s support would play into the hands of Labour leader Jeremy Corbyn, who says the two men are right-wing soul mates who pose a threat to the U.K.’s National Health Service.The Tories Secretly Fear Trump Could Wreck Johnson’s ElectionJohnson is also trying to distance himself from the previous Tory administration after convicted terrorist Usman Khan killed two people on Friday in central London. Khan had been released early from jail in December 2018 and was attending a conference on prisoner rehabilitation when he launched his attack.A poll released Monday added to signs that Labour is slowly eating into the Conservatives’ lead before the Dec. 12 vote. While the Tories stood at 42% in the latest Survation poll, they were ahead by just 9 percentage points, down from 14 two weeks ago.Johnson is seeking to capitalize on his strengths. Voters trust Johnson significantly more than Corbyn on security. A YouGov poll for the Sunday Times showed found 44% of voters have confidence in Johnson. For Corbyn, 67% of voters don’t have confidence in him, while just 21% do.With that in mind, Home Secretary Priti Patel will double down on the Tories’ message that delivering Brexit could bolster U.K. security. She’ll reiterate that Brexit can give back to the U.K. control of its borders to help reduce smuggling of goods, people and curb terrorism.Her comments come amid a row between Johnson and Corbyn over the early release of the attacker. Corbyn blamed a decade of spending cuts to the prison service for weakening its ability to detect the risk, while Johnson pledged to end a 2008 law that was brought in under a Labour government that gives prisoners automatic early release.Patel also will speak following the late October discovery of 39 bodies in the back of a lorry in Kent, southeast England, after having been smuggled across the border into the U.K.“People traffickers don’t think twice about risking people’s lives for profit,” Patel will say. “And most shockingly of all we know that terrorists have been able to enter the country by exploiting free movement.”Corbyn will seek to return to a debate on the cost of living, with a promise to cut train fares through state ownership of the railways. On Saturday, millions of commuters learned they will have to pay an average of 2.7% more for rail tickets from Jan. 2., which is about 100 pounds ($129) more per year.The party leader is due to announce more details of Labour’s plan for public ownership of the railways, including a 33% cut to regulated fares that the party says will save the average commuter 1,097 pounds a year.”Taking back control of our railways is the only way to bring down fares and create a railway network that is fit for the future,” he’ll say.(Updates with Survation poll results in fifth paragraph)To contact the reporters on this story: Jessica Shankleman in London at jshankleman@bloomberg.net;David Goodman in London at dgoodman28@bloomberg.netTo contact the editors responsible for this story: Tim Ross at tross54@bloomberg.net, Steve GeimannFor more articles like this, please visit us at bloomberg.com©2019 Bloomberg L.P.



          

Forest Management drops an ambient record made from Debussy vinyl

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Forest Management drops an ambient record made from Debussy vinyl, the Chosen Few celebrate the legacy of Sauer’s with a Thanksgiving house and disco party, and more. When Gossip Wolf covered Uptown experimental tape label Reserve Matinee last spring, it led to another discovery: Forest Management, the serene drone project of label cofounder John Daniel.…
          

Art Time with Nancy

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Event date: December 10, 2019
Event Time: 09:30 AM - 10:15 AM
Location:
1506 8th St.
Coralville, IA 52241
Description:
A discovery and celebration of a child's creativity!

          

[원서] Donald J. Abraham - Burger`s Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2)-Wiley-Interscience (2003)

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Download : Donald J Abraham Burger`s Medicinal Chemistry and Drug Discovery Drug Discovery and Drug Development (Volume 2) Wiley Interscience (2003).pdf






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[원서] Donald J. Abraham - Burger`s Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2)-Wiley-Interscience (2003) , [원서] Donald J. Abraham - Burger`s Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2)-Wiley-Interscience (2003)화학솔루션 , 솔루션


순서





[원서] Donald J. Abraham - Burger`s Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2)-Wiley-Interscience (2003)
솔루션,화학,솔루션

Donald%20J%20Abraham%20%20Burger`s%20Medicinal%20Chemistry%20and%20Drug%20Discovery%20Drug%20Discovery%20and%20Drug%20Development%20(Volume%202)%20Wiley%20Interscience%20(2003)_pdf_01.gif Donald%20J%20Abraham%20%20Burger`s%20Medicinal%20Chemistry%20and%20Drug%20Discovery%20Drug%20Discovery%20and%20Drug%20Development%20(Volume%202)%20Wiley%20Interscience%20(2003)_pdf_02.gif Donald%20J%20Abraham%20%20Burger`s%20Medicinal%20Chemistry%20and%20Drug%20Discovery%20Drug%20Discovery%20and%20Drug%20Development%20(Volume%202)%20Wiley%20Interscience%20(2003)_pdf_03.gif Donald%20J%20Abraham%20%20Burger`s%20Medicinal%20Chemistry%20and%20Drug%20Discovery%20Drug%20Discovery%20and%20Drug%20Development%20(Volume%202)%20Wiley%20Interscience%20(2003)_pdf_04.gif Donald%20J%20Abraham%20%20Burger`s%20Medicinal%20Chemistry%20and%20Drug%20Discovery%20Drug%20Discovery%20and%20Drug%20Development%20(Volume%202)%20Wiley%20Interscience%20(2003)_pdf_05.gif Donald%20J%20Abraham%20%20Burger`s%20Medicinal%20Chemistry%20and%20Drug%20Discovery%20Drug%20Discovery%20and%20Drug%20Development%20(Volume%202)%20Wiley%20Interscience%20(2003)_pdf_06.gif

MEDICINAL CHEMISTRY AND DRUG DISCOVERY
Sixth Edition Volume 1: Drug Discovery
Edited by

Donald J.Abraham
Department of Medicinal Chemistry School of Pharmacy - r- m Vir iversity

..

Burger`s Medicinal Chemistry and Drug Discovery is available Online in full color at www.mrw.interscience.wiley.com/bmcdd.

A John Wiley and Sons, Inc., Pu…(skip)
[원서] Donald J. Abraham - Burger`s Medicinal Chemistry and Drug Discovery, Drug Discovery and Drug Development (Volume 2)-Wiley-Interscience (2003)





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2018-P $1 Tuvalu Star Trek Discovery 1oz .9999 Silver 2-Coin Set PCGS PR70DCAM

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$99.00 (1 Bid)
End Date: Monday Dec-2-2019 18:13:24 PST
Bid now | Add to watch list

          

Hospitality & Tourism: Barista - Sheraton Denver Downtown Hotel (17001N39) - Denver, Colorado

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Heres To Your Journey with Sheraton Sheraton is one of Marriott Internationals 30 renowned hotel brands. As the worlds leading hospitality company, we offer unmatched opportunities for associates to grow and succeed. We believe a great career is a journey of discovery and exploration. The Sheraton Denver Downtown Hotel, located at 1550 Court Pl, Denver, CO, 80202 is currently hiring a Barista. Responsibilities include: Serve food courses and alcoholic beverages to guests. Set tables according to type of event and service standards. Answer questions on menu selections. Communicate with the kitchen regarding menu questions, the length of wait, recook orders, and product availability. Communicate additional meal requirements, allergies, dietary needs, and special requests to the kitchen. Record transaction in MICROS system at time of order. Check in with guests to ensure satisfaction with each food course and/or beverages. Pick-up trays and clean tables as needed to ensure a clean dining area. Maintain cleanliness of work areas, china, glass, etc., throughout the day. Maintain cleanliness of work and guest areas by clearing, collecting and returning food and beverage items to proper area. Complete closing duties, including restocking items, turning off lights, etc. Present physical and accurate check to guest and process payment. Follow all company and safety and security policies and procedures; report any maintenance problems, safety hazards, accidents, or injuries; complete safety training and certifications. Ensure uniform and personal appearance are clean and professional. Maintain confidentiality of proprietary information; protect company assets. Support all co-workers and treat them with dignity and respect. Support team to reach common goals. Comply with quality assurance expectations and standards. Move, lift, carry, push, pull, and place objects weighing less than or equal to 25 pounds without assistance. Assist with moving, lifting, carrying, and placing of objects weighing in excess of 50 pounds. Stand, sit, or walk for an extended period of time or for an entire work shift. Read and visually verify information in a variety of formats (e. g., small print). Grasp, turn, and manipulate objects of varying size and weight, requiring fine motor skills and hand-eye coordination. Reach overhead and below the knees, including bending, twisting, pulling, and stooping. Move over sloping, uneven, or slippery surfaces and steps. Move up and down stairs and/or service ramps. Welcome and acknowledge all guests according to company standards. Speak with others using clear and professional language, and answer telephones using appropriate etiquette. Perform other reasonable job duties as requested by Supervisors. To apply now, go to: marriott.taleo.net/careersection/2/jobdetail.ftl?job=17001N39 Marriott International is consistently recognized as an employer of choice globally by FORTUNE magazine, DiversityInc and Great Places to Work Institute, among others. Visit marriott.com/careers to learn more about our workplace culture and career opportunities. Marriott International is an equal opportunity employer committed to hiring a diverse workforce and sustaining an inclusive culture. Marriott International does not discriminate on the basis of disability, veteran status or any other basis protected under federal, state or local laws. ()
          

Engineering: Hardware Engineer - Disposal - Colorado Springs, Colorado

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At Northrop Grumman we develop cutting-edge technology that preserves freedom and advances human discovery. Our pioneering and inventive spirit has enabled us to be at the forefront of many technological advancements in our nation's history - from the first flight across the Atlantic Ocean, to stealth bombers, to landing on the moon. We continue to innovate with developments from launching the first commercial flight to space, to discovering the early beginnings of the universe. Our employees are not only part of history, they're making history. No matter the assignment, Northrop Grumman is committed to being a leader in Cyber, Logistics and Modernization, Autonomous Systems, C4ISR, and Strike. For us, it's about more than just performing. It means realizing the values that define us: responsibility, trust, integrity and protecting freedom worldwide. These values inspire and unite our people- who make everything we do possible. The Engineering and Sciences (E&S) organization pushes the boundaries of innovation, redefines engineering capabilities, and drives advances in various sciences. Our team is chartered with providing the skills, innovative technologies to develop, design, produce and sustain optimized product lines across the sector while providing a decisive advantage to the warfighter. Come be a part of our mission! Northrop Grumman Mission Systems (NGMS) is looking for you to join our team as a Hardware Engineer based out of Colorado Springs, CO. What You'll get to Do: Responsible for research and/or product development in system security engineering. Analyzes engineering specifications and drawings; confers with quality, material, manufacturing and subcontractors to provide and obtain technical information; and reviews production schedules and orders. Examines, measures, inspects or tests defective parts for conformance. Evaluates findings to formulate corrective actions. Plans and carries out security measure to monitor and protect sensitive data and systems. Implements and monitors security measures for the protection of computer systems, networks and information. Implements security engineering systems with requirements of business continuity, operations security, cryptography, forensics, regulatory compliance, internal counter-espionage (insider threat detection and mitigation), physical security analysis (including facilities analysis, and security management). Assesses and mitigates system security threats and risks throughout the program life cycle. Validates system security requirements definition and analysis. Implements security designs in hardware, software, data, and procedures. Supports secure systems operations and maintenance. THIS IS NOT A CYBERSECURITY POSITION. Knowledge, Skills and Ability: General frequent use and application of technical standards, principles, theories, concepts and techniques. Demonstrates the skill and ability to perform moderately complex professional tasks. Problem Solving: Provides solutions to a variety of technical problems of increasing scope and complexity as assigned. Solutions are imaginative, thorough, practicable, and consistent with organization objectives. Discretion/Latitude: Work is reviewed for soundness of technical judgment, overall adequacy and accuracy. Works under general supervision. Independently determines and develops approach to solutions. Work is reviewed upon completion for adequacy in meeting objectives. Impact: Contributes to the completion of milestones associated with specific projects. Liaison: Frequent inter-organizational and outside customer contacts. Represents the organization in providing solutions to difficult technical issues associated with specific projects.Basic Qualifications: 2 years with Bachelors, or 5 years similar experience in lieu of a degree; 0 years with Masters Active Secret-level Security Clearance Demonstrate strong people, organizational, presentation and communication skills, written and verbal Ability to work independently with multi-disciplined teams within the program Ability to travel between 10 and 25% of the year Preferred Qualifications: Security + certification or equivalent security relevant certifications Familiarity with remanence security regulations and handling physical and digital media Familiarity with engineering drawings and technical manuals, and the use thereof for operating, maintaining and troubleshooting of equipment What We Can Offer You: Northrop Grumman provides a comprehensive benefits package and a work environment that encourages your growth and supports the mutual success of our people and our company. Northrop Grumman benefits give you the flexibility and control to choose the benefits that make the most sense for you and your family. Your package will include the following: Health Plan Savings Plan Paid Time Off Additional benefits Education Assistance Training and Development Wellness Program Employee Discount Program On-Site Fitness Center (available at some locations) https://benefits.northropgrumman.com/us/en2/BenefitsOverview/Pages/default.aspx Northrop Grumman is committed to hiring and retaining a diverse workforce. We are proud to be an Equal Opportunity/Affirmative Action Employer, making decisions without regard to race, color, religion, creed, sex, sexual orientation, gender identity, marital status, national origin, age, veteran status, disability, or any other protected class. For our complete EEO/AA and Pay Transparency statement, please visit www.northropgrumman.com/EEO. U.S. Citizenship is required for most positions. ()
          

Executive: BI Manager - Denver, Colorado

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Description: Who we are At KinderCare Education, we make it our passion to nurture a sense of discovery, joy, and wonder in every child, every day, at every one of our centers. As the nation's leading private provider in accredited early childhood education, we're committed to delivering the highest-quality child care and educational opportunities for families and the dedicated professionals who serve them.-- We see the greatness in each child, and we believe teachers can change the world. Every day, our more than 33,000 employees create a world of learning, joy, and adventure for more than 158,000 children. Whether you're in one of our centers or providing support from our headquarters in Portland, Oregon, being a part of the KinderCare family means that you care deeply about positively impacting the lives of children and families through the power of education. KinderCare Education has three brands to meet the needs of busy families wherever they need us\:-- ----- We're in neighborhoods with our KinderCare Learning Centers that offer early childhood education and care for children 6 weeks to 12 years old-- ----- We're at offices with KinderCare Education at Work, our suite of family-focused benefits for organizations to offer to their employees, including on-site and near-site early learning centers, Back-up Care for last-minute child care and Care Select-- ----- And we're at schools with our Champions before and after school programs-- Job Summary\:-- KinderCare Education (KCE) is currently building out a new Business Intelligence solution, including an Enterprise Data Warehouse, and utilizing Microsoft SSAS/SSRS/Power BI for reporting and analytics.-- As part of this program, KCE is looking for a hands-on Business Intelligence Manager who thrives in a collaborative work environment. --This role involves collaborating with peers in architecting highly performant solutions that delivers timely actionable information. You will partner with peers to understand business needs and design and develop solutions using the appropriate tools. --The ideal candidate would be a self-starter, thorough in their work, and able to help build up a high competency Analytics practice with a growing team.-- Additionally, the candidate would act as mentor on best practices both for the development team and for the business in their acceptance of the new BI solution, helping them become more mature in terms of the understanding and correct utilization of their own data assets. Job Responsibilities\: The primary responsibility of the Business Intelligence Manager is to lead the team in the analysis, design, programming and production support of the Business Intelligence Solutions.-- You will also be responsible for the creation and support of standards, repeatable processes to deliver high quality solutions, and in evaluating and recommending appropriate solutions that will help achieve corporate objectives. -- Essential Functions\: 1. Provide Business Intelligence solutions including analytics, dashboards and reports to support KCE in making informed decisions that increase the bottom line through improved quality and services. 2. Design, develop and deploy SQL Server Reporting Services (SSRS) Reports, utilizing DAX to create reports from Tabular Model. 3. Manage and Lead a team of developers in the delivery of high value solutions 4. Design, develop and deploy and tune SQL Server Analysis Services Tabular Models (SSAS) as needed 5. Collaborate with the Data Warehouse architect to help design highly performant solutions 6. Collaborate with the Business Analysts in requirements gathering, prototyping and requirements validation. Analyze and verify technical requirements for completeness, consistency, feasibility, and testability. 7. Apply software engineering concepts and best practices to design a solution that meets operational requirements, such as scalability, maintainability, extensibility, and flexibility. 8. Communicate changes, enhancements, and modifications - verbally or through written documentation to project managers, sponsors and other stakeholders. 9. Champion code quality, integrity and reliability throughout the department by designing and promoting best practices. 10. Design and develop appropriate processes and procedures to ensure proactive data quality monitoring 11. Evangelize self-service Business Intelligence and help foster an environment of information-based decisions 12. Champion use of Business Intelligence to promote new capabilities thru user education, demos and discussions 13. Establish and lead the Business Intelligence User Group 14. Collaborate with a cross functional team including QA Analysts, Business Systems Analysts, Data Warehouse Architect and the product owner to ensure strategic alignment and high-quality outcomes 15. Collaborate with Peers to help establish the BI Team as a Center of ExcellenceQualification: Adaptability Requirements\: ------------------ Position requires a high degree of adaptability. --Candidate will be faced with a variety of issues on a day to day basis and will be expected to respond to these issues appropriately while dealing with multiple priorities and task assignments. -- Working Conditions\: ------------------ Work to be performed in a normal office environment during regular business hours.-- Occasional extended work hours when necessary to meet deadlines. -- Experience and Education\: ------------------ BS or BA in computer science, business, or equivalent is required ------------------ 8+ years' experience delivering Business Intelligence solutions using the MSBI Stack (SSIS, SSAS, SSRS) with at least three years as a Team Leader or Manager ------------------ Must have at least three years' experience as a lead BI Architect -- Knowledge, Skills, and Abilities\: -- Technical\: Candidates must have analytical and problem-solving skills in addition to a good grasp of both the technical and business factors of Business Intelligence Solutions Delivery. -- ------------------ Strong understanding of Business Intelligence / Data Warehouse concepts, methods and tools. ------------------ Proven experience designing, developing and deploying Enterprise Business Intelligence solutions to Production. ------------------ High Proficiency in Microsoft Business Intelligence toolset, including\: o---- SSAS (Tabular Model, DAX & MDX a must) o---- SSRS o---- Power BI o---- SSIS knowledge desirable ------------------ Strong understanding of data modeling including star-schema, OLAP and 3N ------------------ Expert level SQL Skills ------------------ Expertise in one or more Visualization and BI Platforms required ------------------ Prior project management experience, preferably in Agile ------------------ Write high quality code that is robust, performant, and easy to maintain ------------------ Prior experience with Predictive Analytics desirable -- Leadership & Attitude\: Candidates should possess an attitude of lifetime learning to stay abreast of the latest technologies and practices. -- Candidates should possess a strong sense of\: Pride, ownership and teamwork Initiative, looking to proactively provide solutions, with the ability to think logically and independently -- Communication\: -- Candidates should possess strong written and verbal communication skills and be able communicate with confidence in any situation. -- KinderCare Education is an Equal Opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, age, sex, religion, disability, sexual orientation, marital status, military or veteran status, gender identity or expression, or any other basis protected by local, state, or federal law.-- ()
          

Where'd You Go Bernadette

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AVAILABLE NOW!

RATED PG

108 minutes


My review for the book.

Based on the runaway bestseller, Where'd You Go, Bernadette is an inspiring comedy about Bernadette Fox "Academy Award winner Cate Blanchett", a loving mom who becomes compelled to reconnect with her creative passions after years of sacrificing herself for her family. Bernadette's leap of faith takes her on an epic adventure that jump-starts her life and leads to her triumphant rediscovery.



REVIEW:
What a great movie!
The hubby and I sat to watch this, I was hopeful, having read the book. He was oblivious.
Throughout the movie, the hubby was ready to bale. I told him to stay, you need to watch to the end. If it was anything like the book, the story really comes together at the end. So he stuck with it, and at the end said it was a great film. That , to me, shows the brilliance of this film.
This movie has a powerful message, not to judge a book by its cover. That is the take away from it.
A great movie for date night or any night.
Though the book was still better. It was funnier, the movie was more drama.


4/5




**Compensation may be earned from the link within. A screener was provided to facilitate this review. Opinions are owned by Freda's Voice.

          

Monster Black Hole That 'Should Not Exist' Discovered in the Milky Way

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An anonymous reader shares a report: Astronomers think our home galaxy -- the Milky Way -- is practically bursting with black holes, with estimates of up to 100 million of the invisible beasts hiding across the galactic neighborhood. It was generally assumed these black holes could reach a mass of up to 20 times that of the sun, but the discovery of a "monster" black hole, with about 70 times the mass of the sun, has surprised Chinese astronomers. In a new study, published in the journal Nature on Nov. 27, a research team from the Chinese Academy of Sciences peered across the galaxy with the Large sky Area Multi-Object fibre Spectroscopic Telescope (Lamost), based at Xinglong Observatory in China. Black holes don't emit light, so astronomers have to get crafty when they go hunting for them. Usually, this involves looking for signs a black hole is feasting on a nearby star or the gas and dust that swirls around them. If the black hole isn't feasting and if it isn't surrounded by bright gas and dust, it becomes a little trickier to locate. But, using Lamost, the team examined the movement of stars across the sky, searching for those that seemed to be orbiting an invisible object. Follow-up observations with telescopes in Spain and the US helped the researchers discover a star about eight times bigger than the sun. Intriguingly, it was orbiting a "dark companion": The monster black hole, dubbed LB-1. "Black holes of such mass should not even exist in our galaxy, according to most of the current models of stellar evolution," said Liu Jifeng, astronomer at the National Astronomical Observatory of China and first author of the study, in a press release. "LB-1 is twice as massive as what we thought possible. Now theorists will have to take up the challenge of explaining its formation."

Read more of this story at Slashdot.


          

World AIDS Day: A Celebration of Life & Light in San Jose

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Lee & Diane Brandenburg Theatre at the Children’s Discovery Museum of San José, 180 Woz Way, San José, CA
          

Enjoy your own personal Gold Rush on Route 49 in California

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WHEN James William Marshall discovered the first nugget of gold at Sutter’s Mill, word of his discovery sparked the Californian Gold Rush of 1848. Today, remnants of this period can be found throughout the Golden State, and nowhere more so than along Route 49 running for 300 miles from Vinton to Oakhurst via Sacramento and connecting travellers to world-renowned sites like Yosemite National Park, Big Trees State Park and Lake Tahoe.
          

Voyage of discovery exploring the Amazon and the Caribbean

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I WATCHED a TV documentary on the mighty Amazon and was smitten, however my wife fancied a Caribbean cruise. Fred. Olsen Cruise Lines solved the domestic, as their good ship Braemar was visiting the Amazon region along with four Caribbean islands.
          

Legoland Discovery Centre and SeaLife Aquarium at the Trafford Centre

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FOR parents of all ages, colours and creeds, Lego will be a staple of every birthday and Christmas.
          

Dental Assistant 2 (Expanded Function Dental Assistant) (EFDA) ~ Dental Clinic | Vanderbilt Health

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Nashville, Tennessee, Description Discover Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating at a global crossroads of teaching, discovery and patien
          

FiercePharmaAsia—Novartis' Shanghai R&D revamp; BeiGene's Imbruvica rival; Shionogi's antibiotic

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Novartis is shutting down its Shanghai R&D site's discovery function in favor of drug development. BeiGene nabbed a landmark FDA nod for Brukinsa, a challenger to J&J and AbbVie's Imbruvica. Shionogi's antibiotic Fetroja won FDA approval with a mortality warning. And more.
          

Land Rover Discovery Service Repair Manual

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Land Rover Discovery Service Repair Manual
          

70001-Merchandise Coor Job in Alpharetta, GA

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<p>All 1,000 of our Marshalls stores embrace discovery, from designer luggage to statement shoes. Our assortment of brands is always changing, but our mission to provide the surpri ... Save as E-mail Job Alert
          

Merchandise Associate Job in Lithonia, GA

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<p>All 1,000 of our Marshalls stores embrace discovery, from designer luggage to statement shoes. Our assortment of brands is always changing, but our mission to provide the surpri ... Save as E-mail Job Alert
          

70230-Customer Experience Coor Job in Buford, GA

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<p>All 1,000 of our Marshalls stores embrace discovery, from designer luggage to statement shoes. Our assortment of brands is always changing, but our mission to provide the surpri ... Save as E-mail Job Alert
          

백트, 비트코인 선물 거래량 계속 경신…COO "BTC 성공하려면 실질적인 유용성 필요"

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세계 최대 거래소 그룹 인터컨티넨탈익스체인지(ICE) 산하 비트코인(Bitcoin, BTC) 선물 거래소 백트(Bakkt)의 수석운영책임(COO) 아담 화이트는 비트코인이 성공하려면 실제적인 유용성이 필요하다고 발언했다.

 

아담 화이트 수석은 26일(현지시간) EJ인사이트와의 인터뷰에서 백트가 시장 투기를 일으키지 않는 상품 구축을 위해 노력하고 있으며, 특히 ‘가격발견(price discovery)’과 리스크 헤징 관리에 있어 백트의 선물 계약이 긍정적으로 역할하고 있다고 강조했다.

 

또 이 같은 시장활용 사례 증가에도 비트코인이 '유용성(utility)'을 갖춰야 한다고 주장했다.

 

그는 "비트코인과 같은 디지털 자산이 실제적인 문제를 해결하는 데 사용돼야 한다. 이를 도입(adoption), 유용성(utility)라고 한다"며 "비트코인의 도입과 유용성을 강화하기 위해 별도의 부서를 두고 새로운 상품과 서비스를 개발하고 있다"고 설명했다.

 

수석은 스테이블 코인에 대해 아직 중립적인 입장이라 밝혔다. 그러면서도 "법정화폐를 담보하는 디지털 자산은 흥미로운 분야"라면서 "향후 위상이 더 높아지면 백트 커스터디 솔루션이 지원할 가능성도 고려한다"고 덧붙였다.

 

페이스북이 추진 중인 스테이블 코인 '리브라' 프로젝트에 대해서는 "규제 반발은 당연하다. 리브라는 전례 없이 경계를 확대해가고 있다"고 평가했다.

 

그는 "이러한 프로젝트가 생겨나고 추진되는 흐름 자체가 중요하다"면서 "문제가 있겠지만 현금 등 다른 것들은 할 수 없는 스테이블 코인만이 할 수 있는 부분이 있을 것"이라 전했다.

 

백트(Bakkt)는 암호화폐 선물 거래소로써 새로운 기관투자자를 유입시킬 것이란 큰 기대를 모았다. 지난 9월에는 실물 인도 비트코인 선물 상품을 출시했으며, 올해 안에 현물 인도 상품을 출시할 계획이다. 그 외 비트코인 옵션 상품도 준비 중이다.

 

비록 출발은 저조했지만 지난 몇 주 간 거래량과 미결제약정이 급증하며 각종 기록들을 연달아 경신하고 있다. 실제로 암호화폐 전문 분석업체 스큐(Skew)에 따르면 백트의 비트코인 선물 미결제약정(open interest) 규모는 100만 달러를 돌파했으며 거래량도 꾸준히 증가 중이다.

 

한편 백트 거래량 봇 트위터 계정 백트봇(@BakktBot)에 따르면, 미국 현지시간 기준 27일 백트 비트코인 선물 거래량이 5,6713 BTC로 역대 최고치를 경신했다. 

 

▲ 출처: 백트봇 트위터     © 코인리더스


이와 관련해 유명 암호화폐 전문 애널리스트 알렉스 크루거(Alex Krüger)는 트위터를 통해 "백트 비트코인 선물의 거래량이 대폭 증가하고 있다. 그러나 중점을 두어야할 점은 거래량이 아닌 실물인수도 규모다. 11월 BTC 선물 실물인수도 규모는 11 BTC, 10월은 15 BTC를 기록했다"고 말했다.

 

 

 


          

Discovery Turbo estreia a sexta temporada de "Invasão de Garagens"

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Divulgação Discovery Turbo
A partir de terça-feira, 3 de dezembro, às 21h20, Bruno Massel e Cristy Lee retornam ao Discovery Turbo para continuarem na missão de resgate a mecânicos e funileiros amadores que estão com projetos de restauração e customização automotiva encalhados há tempos.

Na sexta temporada de INVASÃO DE GARAGENS (Garage Squad), a série segue socorrendo os entusiastas da mecânica e design. Todos os participantes perderam o gás no meio de seus grandes projetos – e, hoje, convivem com as carcaças do que deveriam ser carros possantes, empoeiradas e esquecidas nas suas garagens.

Bruno e Cristy promoverão intervenções drásticas que finalmente devolverão esses carros. Junto a uma equipe de profissionais liderados por Joe Zolper, o restaurador-chefe, Bruno, Cristy e os donos dos carros farão uma transformação completa: motor, transmissão, freios, elétrica, funilaria, tapeçaria, acessórios.

Em cada episódio de uma hora, um participante sortudo recebe a visita da turma de INVASÃO DE GARAGENS. Durante um final de semana de trabalho intenso, os especialistas transformarão esses projetos abandonados em realidade. Na visita de avaliação, Bruno, Cristy e Joe descobrem o trabalho que terão pela frente e discutem as prioridades com o dono do veículo, que vai participar como assistente em todo o processo – com apenas dois dias de força-tarefa, não há tempo a perder!

No primeiro episódio da nova temporada, a equipe da série vai ao socorro de Dee Mihalek, que mandou um vídeo com o pedido de ajuda à produção. O marido dela, Matt Mihalek, precisa de uma forcinha especializada para finalmente restaurar a caminhonete  Dodge 1978 pela qual nutre verdadeira paixão.

A Dodge 1978 tem história. Foi comprada por eles em 1990 e teve que ser vendida durante uma fase de dificuldades financeiras, quando o casal precisava de dinheiro para se casar. Agora, trinta anos depois, o dono resolveu revender a caminhonete para Matt e Dee.  No entanto, a Dodge 1978 está em frangalhos e, por mais que Matt queira dar conta do serviço, os consertos necessários estão muito além da sua capacidade de amador. Ele está há quatro anos tentando coloca-la de volta nas ruas, sem sucesso.   

Bruno, Cristy e Joe fazem a visita inicial e, apesar do carro não dar partida, acreditam que há muito potencial. Será necessário refazer motor, freios, escapamento, suspensão, além de toda a parte de “embelezamento”: tapeçaria, rodas e funilaria.  

          

How to Enjoy Family Gatherings and Potlucks without a Binge Eating Relapse

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Family gatherings and potlucks can be difficult for those of us who are recovering from an eating disorder. It combines two...

The post How to Enjoy Family Gatherings and Potlucks without a Binge Eating Relapse appeared first on Center For Discovery.


          

5 Tips for Coping with an Eating Disorder During the Holidays

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When you’re in recovery from an eating disorder, the holiday season, though it may bring significant joy and excitement, may also...

The post 5 Tips for Coping with an Eating Disorder During the Holidays appeared first on Center For Discovery.


          

6 Tips for Coping With Family Events While Recovering From Binge Eating Disorder

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It can be tough to recover from binge eating and family events don’t make things any easier. Here are 6 tips...

The post 6 Tips for Coping With Family Events While Recovering From Binge Eating Disorder appeared first on Center For Discovery.


          

Coping Methods to Get through Thanksgiving

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Thanksgiving can be a wonderful day filled with family togetherness and traditional foods. It can also be very stressful, due to...

The post Coping Methods to Get through Thanksgiving appeared first on Center For Discovery.


          

Rover Discovery 1995 Mpi Engine Full Service

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Rover Discovery 1995 Mpi Engine Full Service
          

Network Pharmacology-Based Prediction of Active Ingredients and Mechanisms of Lamiophlomis rotata (Benth.) Kudo Against Rheumatoid Arthritis

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Background:Lamiophlomis rotata (LR) showed favorable clinical effect and safety on rheumatoid arthritis (RA), but its active ingredients and mechanisms against RA remain unknown. The aim of this work was to explore the active ingredients and mechanisms of LR against RA by network pharmacology.

Methods: Compounds from LR were identified using literature retrieval and screened by absorption, distribution, metabolism, excretion, and toxicity (ADMET) evaluation. Genes related to the selected compounds or RA were identified using public databases, and the overlapping genes between compounds and RA target genes were identified using Venn diagram. Then, the interactions network between compounds and overlapping genes was constructed, visualized, and analyzed by Cytoscape software. Finally, pathway enrichment analysis of overlapping genes was carried out on Database for Annotation, Visualization, and Integrated Discovery (DAVID) platform.

Results: A total of 148 compounds in LR were identified, and ADMET screen results indicated that 67 compounds exhibited good potential as active ingredients. A total of 90 compounds-related genes and 1,871 RA-related genes were identified using public databases, and 48 overlapping genes between them were identified. Cytoscape results suggested that the active ingredients and target genes of LR against RA consisted of 23 compounds and 48 genes, and luteolin and AKT1 were the uppermost active ingredient and hub gene, respectively. DAVID results exhibited that the mechanisms of LR against RA were related to 34 signaling pathways, and the key mechanism of LR against RA might be to induce apoptosis of synovial cells by inactivating PI3K-Akt signaling pathway.

Conclusion: The active ingredients and mechanisms of LR against RA were firstly investigated using network pharmacology. This work provides scientific evidence to support the clinical effect of LR on RA, and a research basis for further expounding the active ingredients and mechanisms of LR against RA.


          

The Journey to Connect STEM from K to Careers Starts Now! Introducing the STEM Careers Coalition

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On November 8, Discovery Education launched a critical initiative to connect classrooms nationwide, from K to careers.  The STEM Careers Coalition will serve as a conduit through which students can see the work of the future, by providing resources that bring relevancy to learning and broaden students’ understanding of and engagement with STEM. This blog
          

Identification of Major Capsid Protein as a Potential Biomarker of Grouper Iridovirus-Infected Cells Using Aptamers Selected by SELEX

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Biomarkers have important roles in disease pathogenesis, and serve as important disease indicators for developing novel diagnostic and therapeutic approaches. Grouper iridovirus is a nucleocytoplasmic DNA virus, which not only causes great economic losses in mariculture but also seriously threatens the global biodiversity. However, a lack of biomarkers has limited the progress in clarifying iridovirus pathogenesis. Here, we report novel molecular probes, aptamers, for specific identification of biomarkers in grouper iridovirus-infected cells. Aptamers are selected by SELEX, which is a completely different approach from conventional antibody-based methods for biomarkers discovery. Aptamer-based technology is the unique efficient selection for cell-specific target molecules, and helps find out new biomarkers without the knowledge of characteristics of proteins expressed on virus-infected cell surface. With the implementation of a two-step strategy (aptamer selection and biomarker discovery), combined with mass spectrometry, grouper iridovirus major capsid protein was ultimately identified as a potential biomarker of aptamer Q5 for grouper iridovirus infection. The specific interactions of aptamer Q5 and MCP were experimentally validated by several assays, including EMSA, co-localization of fluorescence by LSCM, binding competition tests, and siRNA silencing tests by flow cytometry. This aptamer-based method for biomarkers discovery developed with grouper iridovirus-infected cells could be applicable to other types of virus infection, markedly improve our studies of biomarker discovery and virus pathogenesis, and further facilitate the development of diagnostic tools and therapeutic approaches to treat virus infection.


          

(PSSST *Grandma* Wonkette's Pineapple Orange Cranberry Sauce Is Better, Actually)

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For years now -- seven at least, suckers -- we have been making Aunt Wonkette's Real Cranberry Business. It's great! (Needs more sugar. Not Oprah-level four damn cups, but one would be nice.) But last year, we did not do that. We wanted pineapple, which we almost always have on hand ever since your comrade Vegan & Peeara or whatever she is named these days told us while we visited her in Charleston that pineapples are symbols of hospitality.

So fuck it, we did it live!


First: Do whatever Ken says. Buy two pounds of fresh cranberries! Wash your hands, smoke a joint, pet the dog, wash your hands again, rinse the cranberries and look for pirate teeth. If you make this the night before (or even two or three nights!) you will not have to fight for oven space, but you could do that too on the day, it's fine! Preheat oven to 375, 400, it's all cool. #cookingwithrebecca #dowhatever!

None


Cut your (fresh; always fresh) pineapple. If you have a pineapple slicer, they are so fun and I buy them for everyone, but you do not NEED a pineapple slicer. But it helps because you want small chunks not big "rustic" ones like I do with everything I am ever chopping because #lazy.

None


After you've got your slices, you can just fist that pineapple, just scrape all up and down in there, get all the good stuff.

None


Like Ken said, grate some orange peel onto the cranberries and then squeeze the juice onto it.

None


Glug glug with the bourbon, or use rum! Like the lady in the grocery store said when I saw her fresh cranberries and told her about my pineapple discovery and real quick how to do it with the pineapples and the orange zest and the liquor, WHY NOT BOTH? It's a LONG ISLAND CRANBERRY SAUCE! (I did not use both. That would probably be gross. Do not #dowhatever)

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Cup o' sugar! Don't listen to Ken, a half cup is preposterous.

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Pretty! I put the smallest sprinkle of pumpkin spice across the top and then mixed it all up with a touch more orange juice because that sounded fun. We will see! Cinnamon? Cloves? Vanilla? Nutmeg and ginger? Fuck it! #dowhatever

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Check it after a while, 15 or 20 minutes. Cranberries aren't burst? It's not done yet! That above? That's done. And fucking delicious.


Happy Thanksgiving, loves. See you on the flip!

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Discovery 2 Instructor Lab Manual

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Discovery 2 Instructor Lab Manual
          

"Better Than Stuff" - Shopping For Adventure Gifts from The Adventure Park at The Discovery Museum

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The Adventure Park at The Discovery Museum has created a wide range of gift ticket packages (at prices well below their regular prices) just for the Holiday Season, designed to bring smiles, joyful whoops and memories for a lifetime to the happy recipients.
          

Park Hyatt Doha Hotel opens in Msheireb Downtown Doha

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Msheireb Properties, the national real estate developer and as subsidiary of Qatar Foundation, in collaboration with Hyatt Hotels Corporation (NYSE: H) inaugurated today the first ever Park Hyatt hotel in Qatar in Msheireb Downtown Doha (MDD), the smartest and most sustainable fully-built city district in the world.

The grand opening was attended by HE Akbar Al Baker, Secretary General of Qatar National Tourism Council and Board Member of Msheireb Properties, accompanied by VVIPs, dignitaries, media, and influencers, who also enjoyed a pre-opening tour of the hotel. HE Mr Akbar Al Baker, Secretary General of QNTC and GCEO of Qatar Airways, said during the opening ceremony: “We are very pleased to see the hospitality offering at Msheireb Downtown Doha growing with the opening of their third hotel. In addition to boosting our award-winning hospitality portfolio, the presence of luxurious accommodation options side by side with our heritage treasures in the heart of the city create richer experiences for our visitors.” 

Park Hyatt Doha offers personalized luxury and discreet services for discerning global travellers in the heart of the Qatar’s capital, Msheireb Downtown Doha. With bespoke guest experiences, the hotel is the destination for people who savour subtle elegance, bringing to Qatar the understated luxuries this hospitality brand is famous for around the world.

Developed and owned by Msheireb Properties, Park Hyatt Doha presents 187 distinctive guest rooms and suites, three restaurants, and a luxurious spa spread over two floors, with a separate floor dedicated to men and women. In addition to the more than 2,000 square meters of meeting and event space, the hotel offers 1,750 square meters of recreation and leisure facilities, including a pool, spa, and fitness centre. Ali Al Kuwari, Acting CEO of Msheireb Properties, said: “We are celebrating today the launch of Park Hyatt Doha, another first that Msheireb Downtown Doha introduces in Qatar. The hotel is the outcome of strategic collaborations that reflect the confidence that global brands, such as the Hyatt Group, have in our project. It also embodies the spirit of Msheireb Downtown Doha, focusing on tradition and heritage to build for the future and centring around the community.”

Kurt Straub, Hyatt’s Vice President of Operations for the Middle East, Africa, and South West Asia, said: “We are delighted to bring the Park Hyatt brand to the culturally and creatively rich city of Doha.” “The Park Hyatt brand is dedicated to creating exceptional, intimate and memorable experiences, and we are thrilled to open doors and welcome guests from around the world to this unique location. The introduction of Park Hyatt Doha in Qatar strengthens our vision of being the preferred brand for global travellers and enhances the footprint of Hyatt’s luxury portfolio in the Middle East,” He added.

Stefan Gaessler, General Manager of Park Hyatt Doha, said: “Each Park Hyatt Hotel around the world is custom designed to combine sophistication with a distinctive local character. We have worked with Msheireb Properties to create something in the heart of Doha that integrates with the genuine local culture and connects us to the community. Our design and services reflect the elements that make up the modern Qatari identity with its connection to the past and forward-looking attitude at the same time. We promise our guests a luxurious experience of understated and timeless elegance as that manifested by the story of Qatar along the years.”

Park Hyatt Doha also includes 28 Park Suites, 3 Park Executive Suites, a Diplomat Suite and a Presidential Suite. All rooms enjoy floor to ceiling windows, luxury window seats, and designer marble bathroom with deep soaking tub, rain shower, and double vanity sink. In the Presidential and Diplomat Suites, guests can retreat to a private terrace with magnificent views overlooking the city or Corniche and stunning West Bay skyline. In addition to its wide range of luxurious accommodations, Park Hyatt Doha creates an enriching dining offering through its main restaurant, Opus; offering Qatari and French cuisines in parallel, Anis; a healthy eatery, and the Japanese restaurant and lounge, Sora.

Sora, a tasteful Japanese restaurant and lounge, offers magical views of Doha’s skyline from its high-rise location on the hotel’s 21st floor. Boasting an ultra-modern space where guests can experience a balance of small sharing dishes and the distinctive culinary art of Robata, the restaurant offer the highest panoramic views of Doha in Msheireb. Hosted by Japanese Chef, Takeumi Hiroaka, who is famous for his traditional Japanese cooking gear and attire, the restaurant, is the most authentic Japanese dining spot in Qatar, serving modern versions of traditional favorites such as Robata, Sushi, Sashimi, Tempura and an extensive beverage collection.

Opus offers parallel experiences of Qatari and French cuisines from an open kitchen. Guests can enjoy a “four hands” chef table concept, an expansive open-air terrace as well as private dining options. Qatari-inspired dishes, with menus curated by local celebrity chef, Shams Al Qassabi, and Park Hyatt Paris-Vendôme’s Michelin-starred chef, Jean-François Roquette, present guests the opportunity to experience cultural similarities through cuisine. Anis, on the other hand, is an all day, healthy food eatery creating generous handmade, nutritionally balanced dishes, coffees, juices and smoothies. Boasting direct street entrance, the restaurant is a social hub for health-conscious locals, office workers and visitors of the downtown district.

Park Hyatt Doha hosts a subtly luxurious Spa that serves as a relaxing sanctuary, where therapists take guests on a journey of self-discovery to create bespoke treatments that suit their individual wellbeing needs. Private, elegant, and soothing female and male spa facilities spread across two different floors, will rejuvenate and replenish with exclusive Swiss and Australian product lines and personal health consultants. Spa facilities include; whirlpool, steam room, sauna, outdoor 20m swimming pool and beauty salon, and gyms that are flooded with natural light and equipped with Technogym.

Located on Sikket Al Wadi street, in Msheireb Downtown Doha, Park Hyatt Doha has been built to US Gold LEED certified standards, with a vision to embark on environmentally sustainable initiatives, and collaborations with local suppliers. The hotel is located 16km from Hamad International Airport, and moments away from a Light Rail stop that runs through the precinct, as well as one of Doha Metro’s largest stations, Msheireb Station. The sophisticated hotel is ideally located for business and leisure travellers alike, being in the centre of the city, as well as a short walk from Msheireb Downtown Doha’s four museums, and the traditional Arabian souk, Souk Waqif.

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Fashion informatics and the network of fashion knockoffs

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Knowledge discovery techniques have a long history of application to fields of practice such as marketing and business intelligence. Fashion and other manufacturing compartments have comparably enjoyed little attention from computer scientists. With the increasing availability of multimedia data from the Web and social media, our understanding of the fashion apparel industry could be significantly enhanced through the use of knowledge discovery methods and of large scale datasets obtained from places such as Twitter and Instagram. Here, we are interested in one of the issues at the center of the contemporary structure and dynamics of the fashion industry: the practice of knockoffs. We combine Web scraping and network science techniques to give a preliminary characterization of how brands knock designs off each other. Such a study could be one of the first examples of an emergent field, which we refer to and define as “fashion informatics.”


          

Representing glycophenotypes: semantic unification of glycobiology resources for disease discovery.

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While abnormalities related to carbohydrates (glycans) are frequent for patients with rare and undiagnosed diseases as well as in many common diseases, these glycan-related phenotypes (glycophenotypes) are not well represented in knowledge bases (KBs). If glycan-related diseases were more robustly represented and curated with glycophenotypes, these could be used for molecular phenotyping to help to realize the goals of precision medicine. Diagnosis of rare diseases by computational cross-species comparison of genotype-phenotype data has been facilitated by leveraging ontological representations of clinical phenotypes, using Human Phenotype Ontology (HPO), and model organism ontologies such as Mammalian Phenotype Ontology (MP) in the context of the Monarch Initiative. In this article, we discuss the importance and complexity of glycobiology and review the structure of glycan-related content from existing KBs and biological ontologies. We show how semantically structuring knowledge about the annotation of glycophenotypes could enhance disease diagnosis, and propose a solution to integrate glycophenotypes and related diseases into the Unified Phenotype Ontology (uPheno), HPO, Monarch and other KBs. We encourage the community to practice good identifier hygiene for glycans in support of semantic analysis, and clinicians to add glycomics to their diagnostic analyses of rare diseases.


          

LA TROBE UNIVERSITY: Business Services and Communications Officer

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LA TROBE UNIVERSITY: Challenge yourself in an environment of discovery and innovation to drive service excellence to improve the student experience and success ... Banyule, Australia
          

The ART of Having Children

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The ART of Having Children jbanderson Thu, 11/21/2019 - 09:28 Life and Health Family and Relationships Science and Environment Fall 2019 Interview The ART of Having Children Is Assisted Reproductive Technology the Wave of the Future? Dan Cloer

In the face of increasing options for selecting our future children, author and medical doctor Robert Klitzman asks, “What kind of society do we want in terms of our ability to design babies?”

“I’m looking for a sperm donor,” she said.

So begins Robert Klitzman’s new book. If you’re imagining that Klitzman is a provocative new writer of edgy cosmopolitan fiction, guess again. In Designing Babies: How Technology Is Changing the Ways We Create Children (2020), the medical doctor explores the many ways in which babies are created today. These ARTs (assisted reproductive technologies) may seem like fiction, but they’re not. Increasing numbers of hopeful parents are investing in ART procedures.

In vitro fertilization (or IVF, the bringing together of sperm and egg outside the body) is the core ART process. Since Louise Brown’s birth in 1978, IVF has added more than 8 million babies to both traditional and nontraditional families. But many millions more embryos and pregnancies have been unsuccessful. The grief, frustration and financial costs can be overwhelming; even the relationship between potential parents can be ruined by the unfulfilled dream of having an ART child. Meanwhile, leftover embryos are often kept in a frozen limbo awaiting destruction, gestational adoption, or parental retrieval for another round of treatment and possible birth.

So when a friend asked Klitzman, “Do you want to be the father of my child?” he had plenty to think about. “You wouldn’t have to do anything other than donate the sperm,” she assured him. He writes that although the proposition was “tempting,” he worried, “What if I disagreed with her about how to raise our child?” He eventually told her no.

“I have often wondered if I made the right decision. I will never know. But the choice helped me understand the predicaments that countless potential parents confront.”

Robert Klitzman, Designing Babies

“We now face crucial moral, social, cultural, psychological, and existential conundrums about how to employ these technologies,” he remarks; “whether to monitor or control them and, if so, how; and more broadly, where as a species we are or should be heading; and what responsibilities, if any, we have in these realms.”

Echoing the advice of most scientists involved in this brave new world of designing babies, he writes, “We need now to enhance discussion, awareness and understandings of these issues among patients, their families, clinicians in various fields, professional organizations, policymakers, and the public at large.”

Klitzman is a professor of clinical psychiatry and director of the Masters of Bioethics Program at Columbia University. He also cofounded and codirected the Center for Bioethics and is a member of the Research Ethics Advisory Panel of the US Department of Defense and of the New York State Stem Cell Commission. His previous books include, among others, The Ethics Police? (2015) and Am I My Genes? (2012).

Vision contributor Dan Cloer spoke with Klitzman about what he discovered from writing Designing Babies. The conversation began with Chinese biophysics researcher He Jiankui’s reasons for proceeding with germ-line editing of human embryos.

 

DC He Jiankui created a set of guidelines called “Draft Ethical Principles for Therapeutic Assisted Reproductive Technologies” to support his use of CRISPR for editing human embryos last year. How would you evaluate these principles?

RK They sound good, but we need more than nice words. With ethical principles, God is in the details, so to speak. The issue with any ethical principle is how it will be interpreted and applied. And what does one do when different ethical principles conflict? In general, He’s principles are fine, but they are not complete. Most specifically, what is missing for me is that he does not address questions of risk and external review.

It’s not just that there may potentially be benefits to gene editing down the line, but what are the risks for someone today? Ideally, the CRISPR gene-editing tool might be used to intervene when no alternative treatment exists and the patient will otherwise die. In this case, there are good treatments for HIV and methods for avoiding transmission of HIV to a child. Gene editing was not necessary; the risks outweighed the benefits.

The other crucial element in international ethical guidelines is the need for a process of external review. It’s not enough for scientists to say, “I’m going to cure people. I made this invention in my laboratory, and I’m going to give it to everyone and save their lives!” There must be an outside reviewer to say, “Wait a second. What is it? What are the risks? What are you going to tell people about it?”

We know that every scientist has conflicts of interest. They want their discovery, intervention or innovation to work. Unfortunately, there have been many cases where scientists, in their eagerness to show that their idea works, overlook risks and problems. For instance, one of He’s principles was “Organizations developing genetic cures have a deep moral obligation to serve families of every background.” We know now that he had plans to develop an offshore clinic to design babies for wealthy people around the world, who would come to wherever the clinic was located. That certainly shows a conflict of interest. Was he going to provide services for poor people too? Did he feel obliged by that statement to serve everyone?

DCIVF itself is very expensive—maybe $15–20,000 for one treatment cycle. That’s a high bar for many right now, even before we start adding embryo gene sequencing and, at some point, gene editing. And there is no money-back guarantee.

RKThese technologies can help us and they can hurt us. They have the potential to make us better by eliminating some diseases, but also to make us more unequal by enhancing the children of people who can pay for it.

“I suspect that CRISPR will eventually be introduced at fertility clinics in various countries. Someone will come along and offer something—IQ, physical traits, other abilities—and it will cost thousands of dollars.”

Robert Klitzman

For technologies that we are using right now, like Preimplantation Genetics Diagnosis (PGD, used to examine IVF embryos for abnormalities), we already face questions of equity and access. It’s great that couples who may have inherited genes associated with breast cancer can have embryos examined and screened. But the procedure is expensive and often not covered by insurance. So wealthy people can afford to screen their embryos and maybe remove a disease like breast cancer from their family. Up to now, genetic diseases have been equal-opportunity killers. In the future, I think these conditions may increasingly become diseases of the poor. Obviously a lot of social questions arise when the wealthy can remove a mutation from their gene pool while others cannot.

DCYou say that your views concerning infertility changed while writing Designing Babies. “What I saw astonished me,” you write. “These men and women shed light on the myriad, unforeseen facets and ramifications of these new technologies and dramatically altered my views.” How so?

RKI started out in some ways wary of altering the genes of future generations. But I quickly realized that there are times when it might be helpful. PGD can be used to get rid of serious diseases. The key issue is to avoid bad uses and reduce the risks. Rather than saying that designing babies will be either good or bad, the question is when is it good, and when is it bad? It is not monolithic.

DCDo you see any ethical problem in creating IVF embryos that will be tested and rejected or passed on from the clinic to the lab to be used in research? What about surrogate gestation?

RKPersonally, no—but informed consent is important. We have hundreds of thousands of unused embryos in this country. Couples understandably don’t want to throw them out, but sometimes they don’t want to pay for storage either. But what is the moral status of an embryo? This is also an important question in the abortion and stem-cell debates. My opinion is that if a couple is trying to avoid passing on a gene associated with a serious disease, and some embryos have that gene, then it’s okay not to use these embryos. These are unfortunate choices that have to be made.

Similarly, I was quite wary of the idea of buying and selling eggs or sperm, or women renting their wombs [as gestational surrogates]. There are real concerns about exploitation of women and horror stories of children abandoned when the prospective parents changed their minds and no longer wanted the child after the surrogate gave birth. But as I looked into the issue through my interviews and learned about the women who were gestational surrogates, I found that many of them were not, in fact, being exploited. They knew what they were doing: “Hey, I have two or three kids of my own and if I can make $90,000 just sitting around the house, that could help me pay for my kids’ college education.”

DCSo you began to think differently because you were no longer just at your desk mulling it over academically?

RKExactly right. I wrote this book because the public debate is still focused on whether these technologies are “good” or “bad.” What’s missing are the voices of people who are personally involved, invested. Gloria Steinem tells the story of potential exploitation and impoverished women being forced to be surrogates against their will. At least in the US, the data do not support that. Certainly exploitation is bad, and we want to avoid it. But it’s not clear to me that it is happening. Doing research and finding out what the lived experiences are from the people involved really opened my eyes.

This speaks to the fact that many people don’t yet know much about these technologies. It’s true of gene editing but also of other forms of ART: buying and selling eggs and sperm, renting wombs. It affects lots of people but goes largely unexamined because there are taboos against talking about sex and reproduction. Men don’t like to talk about impotence and low sperm count, feeling it means they are not “macho.” Women feel great shame about the fact that their eggs aren’t working or that they’ve had to buy someone else’s eggs, and that they are therefore not genetically related to their child. There’s secrecy and fear. Parents are afraid that their daughter won’t love them as much if she finds out that her mom is not actually her genetic mother. But these secrets have costs. Kids may find these things out later and can become very upset and feel betrayed. Evidence suggests that children should be told from an early age that other people helped bring them into the world, or however a parent might want to communicate that.

I also came to realize how prevalent these issues are. In Denmark, for example, 7 percent of all births occur through some form of ART, and I believe that will soon be the number in the US. This is a big issue that we need to pay more attention to, on both the personal and the policy level. The CDC [Centers for Disease Control] collect some data, but there’s more to do.

DCWe don’t collect and apply data very well, you say. But there are things potential users of these technologies should know—darker things that you learned as well.

RKWe do need data, but some issues stand out even now. We know that over 40 percent of twins born through IVF have medical problems. Yet fertility doctors, using IVF, commonly implant multiple embryos to increase the odds of a successful birth; it’s a selling point for the clinic. If I’m an IVF doctor, I can say, “Look at how many live births I have.” It’s good marketing, but not so good for the baby. I did not know this, and many IVF patients don’t know it either. That’s why many European countries that provide national health-care coverage for IVF and for neonatal intensive care units have much stricter rules than we do in the US concerning the number of embryos doctors can transfer into the womb.

A lot of data could be readily gotten, but reporting is not mandatory, and many clinics don’t want to provide their statistics. Clinics that don’t report are actually increasing their business, so there’s almost a reverse incentive. Changes in policy could address this problem, but unfortunately the lack of data is not accidental. Many clinics don’t want to tell potential customers that there may be problems; they just want to say, “We’ll bring a baby into your life.” Some clinics don’t want young women they recruit as egg donors to fully understand that the procedures might cause harms, such as Ovarian Hyperstimulation Syndrome, which can have serious symptoms. Collecting and publishing more data might reveal limitations and dangers.

“I would say that more information is better for those who are considering using these procedures; but some IVF doctors don’t want all the data out there, and they have had sway.”

Robert Klitzman

DCYou’ve called the ART industry in the United States a kind of Wild West in terms of the relative lack of regulation. Is there a business opportunity here to form some sort of watchdog group?

RKThe American Society for Reproductive Medicine (ASRM) and other physician organizations have done a good job of coming up with guidelines in many areas, but I think they can go further. For example, ASRM permits selecting the sex of a baby for “family balancing.” But what does that phrase really mean? A couple has one girl and now wants a boy? Or they have four girls and now want a boy? The organization needs to be more specific. The question of enforcement also arises. In terms of egg donation, we know that young women’s eggs are biologically better. But should a doctor try to get 18- to 21-year-old women to sell their eggs? How risky is this for their own reproductive future? Guidelines say doctors should not recruit such young women, but clinics often do so anyway. Hence, even when there are guidelines, many clinics don’t follow them and resist stronger guidelines. Today there’s little if any consequence for not adhering to them.

In this “Wild West,” cowboys are often doing what they want without too much supervision. There are many wonderful IVF doctors; by no means am I saying they are all bad. But oversight and greater openness to potential limitations are important.

The danger of jumping in right now and attempting to design babies using CRISPR/gene editing is that we really don’t know the full effects. Patients should be able to make fully informed decisions.

DCIn the real Wild West, people knew it was wild because they had a model of what civilization looked like. But we don’t have a model for reference. We’re building from scratch.

RKYes. Part of this is because of ever newer technologies. But just as with implanting multiple embryos, doctors widely used—and sometimes still use—technologies that turned out to be more harmful and less beneficial than thought. A technique called ICSI [intracytoplasmic sperm injection] took one sperm from a man with a very low sperm count and injected it directly into an egg. Now ICSI is used for two thirds of all patients, without regard to the man’s fertility. But the procedure turns out to double the risk of the child having intellectual disabilities. Unfortunately many potential parents don’t realize this. It may help get you pregnant, but it can cause problems.

A major challenge of the “Wild West” is that doctors might be making a lot of money but may not always communicate the risks as well as they should, because they have a conflict of interest: profiting from what they’re doing.

DCWhere do your books Designing Babies and Am I My Genes? overlap?

RKAt one point scientists thought they would discover the cancer gene, the alcoholic gene, the schizophrenia gene. But lo and behold, we’re finding out that for most common diseases and traits, many genes are involved. Diseases can also be partly genetic, partly environmental. There’s a lot of nuance.

“Listing the potential causes of a disease is like describing the possible reasons for a traffic jam: Did a car break down? Was there an accident? Is a bridge closed? Is it icy? Is it rush hour? Or some combination of those?”

Robert Klitzman

Several companies market direct-to-consumer genetic testing, pushing the idea that these services will “give you important health information” and “help you get control of your health.” Precision medicine can indeed potentially help many people. But our genetics are complicated. Am I My Genes? explored how genetic testing serves almost as a Rorschach, with people interpreting the information in varying ways.

The idea for Designing Babies grew from my work on Genes. When I interviewed people at risk for Huntington’s, I thought I would hear about issues of discrimination or insurance. But what I heard was concerns about their kids—whether to adopt or abort, or to test embryos. I heard a very disturbing observation: “If I abort or don’t choose an embryo because it has the same mutation that I have, I should have been aborted; am I saying that my life was not worth living?” That question still haunts me. It made me want to investigate further the ethical, moral, social and psychological questions that assisted reproductive technologies present us.

The common element and challenge that comes from both books is that we still know relatively little about genes. It’s been only 60 years or so since the discovery of the DNA helix and how hereditary information is encoded. The human genome was first sequenced less than 20 years ago. Much of what we have found is not what we expected.

DCYou write about “individual procreative liberty.” Do you have any concern that in the future parents might be pressured to use ART to avoid creating an “imperfect” child? Could there be a time when national health care includes or compels IVF, and that parents who opt to have children with disease will be ostracized and lose access to social services because they willingly brought a baby into the world that would require more than its share of medical and support resources?

RKPast attempts to improve the genes of people led to horrific results. Nazi Germany sought to remove bad genes by killing people. Hitler got his ideas about eugenics from the United States and our unfortunate history of racism. In the 1920s, we had eugenics fairs and better-baby contests. So we need to be very careful about efforts to improve our genes.

Given our history, however, it’s hard to predict what the government will do. We know that at one point the government pushed sterilization of the so-called feebleminded. And the question of abortion is obviously very contentious.

The cost of IVF will be an important factor in shaping its possible future. We don’t have enough money to provide basic health services to all citizens now. So even if IVF becomes more accessible and less expensive, which I think it will to a certain degree, I don’t think it will ever be mandated. People just get pregnant “naturally” all the time, planned or unplanned. I don’t think we’re going to get to the point where we’ll just not support you unless you used IVF.

DCWhat is the most important question your book helps us explore?

RKWhat kind of society do we want in terms of our ability to design babies—whether choosing or discarding certain embryos; buying and selling human eggs, sperm, and embryos; or altering genes directly?

As with all technologies, ARTs can be used for good or for bad. How do we choose the good over the bad? Do we want to live in a world where people use all of these technologies with few limits? Undoubtedly everyone in America knows someone, whether they realize it or not, who has had infertility problems and has used these technologies. These patients’ journeys have often been lonely and isolating.

I think the book can help open up the conversation and assist us all—as individuals, as friends and family members, and as a society as a whole—in figuring out how best to use these technologies for our own good.

#0D0084 #00AED1
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Pet Shop Boys - Discovery Live In Rio / 1994 / LDRip от Лумина

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Категория: Музыка
Размер: 1.45 GB
Траффик: Раздают (отдают): 3, Скачивают (качают): 1
Добавлен: 2019-11-26 12:21:50
Описание: Оригинальное название: Pet Shop Boys - Discovery Live In Rio
Год выпуска: 1994
Жанр: Pop
Выпущено: Бразилия, Picture Music International Release
Исполнитель: Pet Shop Boys

Описание: Tур по странам Латинской Америки и Австралии. Концерт в Рио Де Жанейро по эмоциональному настрою публики был, пожалуй, одним из самых запоминающихся за всю историю гастролей Pet Shop Boys.

01. Tonight Is Forever
02. I Wouldn't Normally Do This Kind Of Thing
03. Always On My Mind
04. Domino Dancing
05. To Speak Is A Sin
06. One In A Million / Mr. Vain
07. Paninario
08. Rent
09. Suburbia
10. King's Cross
11. So Hard
12. Left To My Own Devices / Rhythm Of The Night
13. Absolutely Fabulous
14. Liberation
15. West End Girls
16. Can You Forgive Her?
17. Girls And Boys
18. It's A Sin / I Will Survive
19. Go West
20. Go West (Reprise)
21. Being Boring

Качество: LDRip
Видео: XviD, 1894 Кбит/с, 688x512, 23.976 fps
Аудио: Английский (AC3, 2 ch, 256 Кбит/с)
Продолжительность: 01:36:11
Перевод: Не требуется

Релиз: http://picplus.ru/img/1902/09/3dbacf35.png от http://s002.radikal.ru/i198/1306/cb/972fbdf9be7a.gif

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Pharmacy Technician | Vanderbilt Health

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Nashville, Tennessee, Description Day Shift - Pharmacy Technician Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating a
          

Pharmacy Technician | Vanderbilt Health

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Nashville, Tennessee, Description Day Shift - Pharmacy Technician Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and operating a
          

Pharmacy Technician-2nd Shift | Vanderbilt Health

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Nashville, Tennessee, Description Pharmacy Technician III Discovery Vanderbilt University Medical Center: Located in Nashville, Tennessee, and o
          

Children as Teachers

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“I always turn to children to be my teachers when I come up against new ideas and challenges,” writes Deb Curtis in her popular book, Really Seeing Children. “And, indeed, observing closely and reflecting on how children engage in exploration and discovery reinforced the notion that children, in fact, do more with less.”

Curtis describes what she’s learned from children about not feeling like we have to offer such a wide variety of toys. “Imagine not offering babies any toys until they find their hands for play,” she writes. “My mind started spinning as I heard Janet Gonzalez-Mena describe this approach used by Pikler Institute in Budapest, Hungary, where they have documented over 75 ways that babies learn to use their hands for play.”


          

Reflective Wheel Stripes

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Found these on a Greek site, Moto-Discovery. Inexpensive compared to the other reflective stripes I could find, VFR-specific and very rapid delivery. They don't quite fit as advertised in the instructions, they overlap when you get back round to the start, but it's easily fixed by reducing the distance between some of the sections. We'll see how they last an English winter. Lots of other VFR/VFR800X bits on there too.
          

Search Day 2019

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La 12ème édition de Search-Day, événement en accès gratuit sur la recherche en information stratégique et la maîtrise des environnements complexes, organisé par Veille Magazine, aura lieu le mardi 10 septembre 2019 (de 9h00 à 18h00) à : MBA ESG avenue Philippe-Auguste 75011 Paris.

Présentation

De la veille à la Content Intelligence. Etudes de cas, retours d'expériences, keynotes

L’intelligence stratégique demande la mise en cohérence des objectifs majeurs de l'organisation et appelle le déploiement d'une gouvernance informationnelle. Ici se situe le point de convergence entre les problématiques de recherche, de veille, d'analyse et d'aide à la décision. Les facteurs-clés de succès de ces dynamiques sollicitent la mise en synergie de démarches de gouvernance métiers :

  • des différents systèmes d'information internes et externes,
  • la maîtrise et la qualification des sources, des connaissances, des flux et des données,
  • la prise en considération des usages réels des utilisateurs métiers.

Thématiques 2019/2020

  • Discovery search, data intelligence, visualisation décisionnelle, mobilité, social monitoring
  • Droit des technologies et technologies du droit, RGPD, intelligence normative. Protection du patrimoine : PI, cyber-sécurité, Data Asset Management,
  • Web mining, ,Analyse sémantique,Intelligence artificielle, reconnaissance vocale, faciale...
  • R&D,Brevets, juridique, financière, media sociaux... Comment qualifie-t-on les sources ?
  • Spécificités d'une ingénierie projet dans le domaine de la veille.

 

sep 10 2019, 9:00am - 5:45pm CEST
PARIS, 75011, MBA ESG PARIS
Rubrique: 
Illustrations: 
Type d'évènement: 
Localisation: 
POINT (2,393596 48,851683)

          

December's SLAS Discovery Special Issue Now Available

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Newswise imageIn this issue, Guest Editor Veli-Pekka Jaakola, Ph.D., (Confo Therapeutics, Belgium) includes a series of articles focused on new screening tools and assays that find new chemical matter for medically relevant membrane protein targets. In addition, an overview of a new and emerging protein-lipid reconstitution methodology utilizing Styrene Maleic Acid (SMA) polymers is featured.
          

Gift of Sight Discovery Fund Supports Sight Saving Research at UW

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Gift of Sight Discovery Fund Supports Sight Saving Research at UW Lions Eye Bank of Wisconsin (LEBW) Gift of Sight Discovery Fund was created in 2015, in partnership with the UW Department of Ophthalmology and Visual Sciences, to promote innovative research to better understand and treat blinding diseases. Department researchers are encouraged to apply annually [...]

The post Gift of Sight Discovery Fund Supports Sight Saving Research at UW appeared first on Lions Eye Bank of Wisconsin.


          

Looking for a Boost? Could CBD be the Answer?

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CBD explained image

You might have heard of CBD. You might have seen it being advertised in health food shop windows or talked about on TV, for example. CBD – or cannabidiol has been growing in popularity over the last few years, with the discovery of more and more health benefits that it can offer to you.

CBD is a natural compound that is found in the cannabis plant. Researchers have found, over the past few years, such an increase in the potential positives to taking CBD that it’s now impossible to ignore and which has none of the negatives that have traditionally been associated with the plant.

What is CBD?

Cannabidiol is one of over 100 compounds that can be extracted from the cannabis plant. It was only discovered recently when scientists were investigating why it is that some civilisations have sworn by the medicinal properties of cannabis for thousands of years.

They found that an important part of the plant was CBD – a phytocannabinoid – which can affect the human body, bringing about a number of health benefits.

The human body has a system called the ‘endocannabinoid system’ – one which is responsible for regulating certain aspects of the body, including the central nervous system and the immune system. In basic terms, it keeps levels of certain chemicals in the ‘Goldilocks Zone’ – not too much, not too little, just right.

The endocannabinoid system works through the interaction between endocannabinoids (cannabinoids made in the body) and cannabinoid receptors. CBD acts in a similar way to the endocannabinoids and can, therefore, help to keep some bodily functions regulated.

What Can CBD Do for You?

Research shows that there’s a whole host of potential health benefits of CBD based on the different parts of the body which can be affected by the endocannabinoid system – as well as a ton of anecdotal evidence. CBD is great for your general health and well-being, but also in some more specific areas.

Some of the areas that CBD could help with include:

  • Central nervous system
  • Control of inflammation
  • Immune system
  • Digestive system
  • Mood
  • Sleep issues

As a direct result of this, you might find that CBD can help with:

  • Anxiety
  • Problems sleeping
  • Arthritis
  • Neuropathic pain
  • Neuroprotection (helping to protect the brain from illnesses such as Alzheimer’s)
  • Skin issues
  • Heart health

In fact, the list of potential benefits of CBD is almost endless. It essentially brings your body back into balance and helps it to help itself.

What’s the Difference Between CBD, Cannabis and is it Legal?

As we have already said, CBD is a compound found naturally in the cannabis plant and is completely legal. The illegal part of the cannabis plant is another compound called Tetrahydrocannabinol (or THC). This is the compound that makes you high, and, although can also be useful for certain medical issues, cannot be bought in the UK without a medical marijuana prescription.

CBD products are made from hemp, which is a strain of cannabis that has been cultivated especially to have higher levels of CBD and very low levels of THC. In fact, for it to be legal and defined as ‘hemp’ it must have less than 0.2% THC. To put that into context, strong marijuana can have a concentration of up to about 20%.

In other words, the levels of THC in hemp are extremely low and you would have to consume massive (and nigh-on impossible) amounts of it to get high.

How to Take CBD

One of the best things about CBD is there are many different ways that you can take it. Which method you decide on depends on why you are taking it and your personal taste. Methods include:

CBD Oil

CBD oil usually consists of the CBD extract which is mixed with a carrier oil which helps it to be absorbed into the body. It can be added to food, or, as is most common, taken in drops under the tongue. Sublingual drops can get to work very fast as the CBD is absorbed through the lining of the mouth and passes into the blood vessels near the surface.

The CBD will come into effect within about 15 minutes if taken sublingually but won’t stay in your system for very long either. The best CBD oils will come with a dropper to make dosing accurate and can be flavoured to help to disguise its grassy flavour.

CBD Capsules

Another option is CBD capsules. These will go through your digestive system and take a couple of hours to work. However, the CBD will stay in your system for up to eight hours, giving you a good base of CBD all today.

CBD capsule dosages are exactly measured out, meaning that you’ll have an absolutely accurate dose.

CBD Edibles

Whether you’re buying CBD chocolate, gummies or putting the oil in your food, CBD edibles work in the same way as the capsules. They are absorbed through the digestive system, take about two hours to work, but can stay in your system for up to eight hours.

Edibles can be an enjoyable way to take CBD and dosing is exact – of course, if you are adding your own CBD to your food, the amounts that you are putting in will be down to you.

CBD Topicals

CBD topical creams and gels are a great way of using CBD for the skin or inflamed muscles or joints. It doesn’t enter the bloodstream so you can just rub it in as and when you need it.

CBD is safe to use, non-addictive and has no long term side effects. However, if you are taking medication you should speak to your doctor before trying CBD as it can affect the way that the body metabolises certain drugs.

As an over 50 you are probably a little more conscious of your health than you used to be. CBD has the potential of being very beneficial to everyone, so why not give it a go?…


          

Astronomers find stellar black hole so large it shouldn't exist

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Just because there's a picture of a black hole doesn't mean astronomers have figured out how they work. Chinese-led researchers have detected a stellar black hole in the Milky Way with a mass so large that it breaks current stellar evolution models. LB-1, a black hole 15,000 light-years away, has a mass 70 times greater than that of the Sun -- previous estimates suggested that no stellar black hole would have more than 20 times the Sun's mass. Scientists expected many dying stars to shed most of their gas, making something this large impossible without readjusting theories.

Via: CNN

Source: EurekAlert, Nature


          

Post Doctoral Fellow | Eisai Inc.

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Cambridge, Massachusetts, Current Postdoctoral Fellowship Opportunities Successful translation of findings from analysis of human data into the wet lab and back is a foundation of G2D2’s approach to drug discovery. A particula
          

[Breaking the Glass] Ep. 6b - Stand on a Chair Pt. 2

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Last month I had a great conversation with 30+ year editing and producing veteran Chris Fenwick about what it takes to make it in this business. He used the analogy of "standing on a chair" to make a point. In the context of that conversation was his commentary about a female assistant editor in Hollywood who as featured in the second installment of our Breaking the Glass docu-film series. The editor, Christine Haslett, shared frustrations about not advancing as far as she would've liked in her field. JD heard Chris' commentary on her situation and felt in the context of Christine, the "stand on a chair" analogy was not only way off the mark, but he felt it also sabotaged the very message "Breaking the Glass" series is trying to convey. As he put it, "He wanted to knock the guy over who was standing in the chair" (albeit, the way he described it was a tad more, um, colorful. :)

This is an episode that will make you laugh and/or get pissed (I'm sure you'll get mad at somebody in this episode). But most of all, I hope it makes you think.

Here's the first episode of FCPX Grill after its 14-month hiatus.

About the Mini-series

Breaking the Glass is a Radio Film School podcast mini-series and short film docu-series addressing the issues of gender inequality in film and television. You can catch all the podcast and video episodes at daredreamer.fm/breakingtheglass.

Videos

Here's the BTG film episode referenced in this episode.

Here's Dane Sanders' keynote address at Engage15 that is referenced (the inspiration for Chris' "Stand on a Chair" metaphor).

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Music

Music in this episode was curated from FreeMusicArchive.org. Songs in order of appearance were:

Click here to learn about Creative Commons licenses and meanings.


          

The Best of RFS Stories Pt. 2 - GUEST Stories

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Statistics show that most podcasts peter off in the first six weeks. We're now six MONTHS strong into ours, and it's only getting better (IMHO). Six months of a "Radiolab" and "This American Life" style show about the art and craft of cinema and filmmaking, delivered EVERY WEEK, has been quite a feat. Six months of stories that will inspire, encourage and/or just flat-out entertain. Whether you're a filmmaker, a photographer, or any other kind of artist, the themes and topics we explore will connect with you.

To celebrate this milestone, we're looking back at some of our favorite stories. Tuesday I shared a few of my favorite personal stories. Today, I'm sharing a few guest stories that have stood out to me:

  • Sky City Haya producer Thom Weinland's funny discovery" about the "Wizard of Oz"
  • Me and show regular JD get into one of our typical debates
  • Celebrated spoken word artist Marshall Davis Jones is back with the funny story behind how he trained his voice and testing it out on John Leguizamo
  • FilmRiot host Ryan Connolly shares how absolutely everything went wrong on his "U.F. Oh Yeah" film set
  • Phillip Bloom offers filmmaking perspective
  • Peabody award-winning filmmaker Elaine McMillion Sheldon and I talk about women in film
  • And award-winning wedding filmmaker Kevin Shahinian gives valuable insight about finding your style

Legally License Music for Your Production

If you need to legally license music for your productions, from every genre, look no further than Song Freedom. Click here and use offer code radio for a one-time Standard Gold Level license worth $30.

Learn How Stillmotion Tells Emmy Award-winning Stories

Stillmotion's Muse Storytelling is the process they use to tell the kind of stories that has helped them garner five Emmys, and go from shooting weddings to shooting the Super Bowl. They've generously offered our listeners a special offer. Details are in the episode.

Grow in Your Craft and Career

We're also supported by YOU, the listeners. Become a Dare Dreamer FM Premium member and gain access to bonus episodes, ebooks, templates, and other resources to help you grow in your craft and career.

Music in this Episode


          

Full Size Bed With Trundle And Storage Drawers

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